PolygenicPathways

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PolygenicPathways

metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

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polygenicpathways

metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

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Other names: polygenicpathways

The datasets list genes, environmental risk factors and autoantibodies in a number of polygenic diseases and provide KEGG pathway analysis etched out by susceptibility genes. Host/pathogen interactions are also characterised for herpes simplex, helicobacter pylori and the HIV-1/AIDS virus.

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Publications

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Schizophrenia susceptibility genes directly implicated in the life cycles of pathogens: cytomegalovirus, influenza, herpes simplex, rubella, and Toxoplasma gondii
PMID: 18552348

metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

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• Schizophrenia susceptibility genes directly implicated in the life cycles of pathogens: cytomegalovirus, influenza, herpes simplex, rubella, and Toxoplasma gondii PubMed citations: 47.

  47 articles citing: Schizophrenia susceptibility genes directly implicated in the life cycles of pathogens: cytomegalovirus, influenza, herpes simplex, rubella, and Toxoplasma gondii

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  Prolonged activation of cytomegalovirus early gene e1-promoter exclusively in neurons during infection of the developing cerebrum. PMID:33750455

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  Improving Therapeutic Interventions of Schizophrenia with Advances in Stem Cell Technology. PMID:32702214

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  Prior Toxoplasma Gondii Infection Ameliorates Liver Fibrosis Induced by Schistosoma Japonicum through Inhibiting Th2 Response and Improving Balance of Intestinal Flora in Mice. PMID:32295161

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  NBIA: a network-based integrative analysis framework - applied to pathway analysis. PMID:32144346

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  Maternal fatty acid concentrations and newborn DNA methylation. PMID:31858113

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  Comprehensive functional annotation of susceptibility SNPs prioritized 10 genes for schizophrenia. PMID:30705251

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  Immune Responses Induced by HSP60 DNA Vaccine against Toxoplasma gondii Infection in Kunming Mice. PMID:29996627

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  Maternal Immune Activation During the Third Trimester Is Associated with Neonatal Functional Connectivity of the Salience Network and Fetal to Toddler Behavior. PMID:29487127

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  Expression of schizophrenia biomarkers in extraocular muscles from patients with strabismus: an explanation for the link between exotropia and schizophrenia? PMID:29302405

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  Our (Mother's) Mitochondria and Our Mind. PMID:28937858

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  Toxoplasma gondii and Neospora caninum induce different host cell responses at proteome-wide phosphorylation events; a step forward for uncovering the biological differences between these closely related parasites. PMID:28803361

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  Uniting the neurodevelopmental and immunological hypotheses: Neuregulin 1 receptor ErbB and Toll-like receptor activation in first-episode schizophrenia. PMID:28646138

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  Integrative transcriptome network analysis of iPSC-derived neurons from schizophrenia and schizoaffective disorder patients with 22q11.2 deletion. PMID:27846841

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  The association between antibodies to neurotropic pathogens and schizophrenia: a case-control study. PMID:27336045

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  N-acetylgalactosaminyltransferases in cancer. PMID:27322213

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  The known and missing links between Toxoplasma gondii and schizophrenia. PMID:27041387

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  Animal models of gene-environment interaction in schizophrenia: A dimensional perspective. PMID:26510407

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  Immune aging, dysmetabolism, and inflammation in neurological diseases. PMID:26089771

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  Maternal exposure to sexually transmitted infections and schizophrenia among offspring. PMID:26022653

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  Understanding schizophrenia as a disorder of consciousness: biological correlates and translational implications from quantum theory perspectives. PMID:25912536

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  ZNF804A Transcriptional Networks in Differentiating Neurons Derived from Induced Pluripotent Stem Cells of Human Origin. PMID:25905630

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  Prenatal maternal immune disruption and sex-dependent risk for psychoses. PMID:25065485

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  MicroRNA-206: a promising theranostic marker. PMID:24465270

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  DISC1 mouse models as a tool to decipher gene-environment interactions in psychiatric disorders. PMID:24027503

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  Human cytomegalovirus UL76 elicits novel aggresome formation via interaction with S5a of the ubiquitin proteasome system. PMID:23966401

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  Future perspectives on the treatment of cognitive deficits and negative symptoms in schizophrenia. PMID:23737409

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  Toxoplasmosis and Polygenic Disease Susceptibility Genes: Extensive Toxoplasma gondii Host/Pathogen Interactome Enrichment in Nine Psychiatric or Neurological Disorders. PMID:23533776

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  Peptide sharing between influenza A H1N1 hemagglutinin and human axon guidance proteins. PMID:23378012

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  Exploring the pathogenetic association between schizophrenia and type 2 diabetes mellitus diseases based on pathway analysis. PMID:23369358

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  Effects of two commonly found strains of influenza A virus on developing dopaminergic neurons, in relation to the pathophysiology of schizophrenia. PMID:23251423

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  Genetics of schizophrenia from a clinicial perspective. PMID:23057976

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  Toxoplasma gondii and cognitive deficits in schizophrenia: an animal model perspective. PMID:22941742

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  Network-assisted Causal Gene Detection in Genome-wide Association Studies: An Improved Module Search Algorithm. PMID:22898890

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  Schizophrenia: a pathogenetic autoimmune disease caused by viruses and pathogens and dependent on genes. PMID:22567321

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  Association study of interleukin-4 polymorphisms with paranoid schizophrenia in the Polish population: a critical approach. PMID:22528336

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  Exposure to herpes simplex virus type 1 and cognitive impairments in individuals with schizophrenia. PMID:22490995

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  DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders. PMID:22461775

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  Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients. PMID:22393424

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  The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease. PMID:22389816

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  Genome-wide association study of antidepressant treatment-emergent suicidal ideation. PMID:22030708

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  The mind-body-microbial continuum. PMID:21485746

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  The viral theory of schizophrenia revisited: abnormal placental gene expression and structural changes with lack of evidence for H1N1 viral presence in placentae of infected mice or brains of exposed offspring. PMID:21277874

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  An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes? PMID:21270935

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  Cross-domain neurobiology data integration and exploration. PMID:21143788

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  Promoter variant of PIK3C3 is associated with autoimmunity against Ro and Sm epitopes in African-American lupus patients. PMID:20671926

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  Fibroblast growth factors in schizophrenia. PMID:19429845

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  The neurodevelopmental hypothesis of schizophrenia, revisited. PMID:19223657

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model organisms

metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

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molecular interactions, pathways and networks

metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

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immunoproteins, genes and antigens

metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

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pathology

metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

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virology

metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:09.034047

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model organisms molecular interactions, pathways and networks immunoproteins, genes and antigens pathology virology