PROMISCUOUS

Names
More detailed information about this field from each metasource.

PROMISCUOUS
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:54.526649

promiscuous
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:54.526649

Other names: promiscuous

Protein-protein and drug-protein interactions for studies of drug repositioning

Webpage:

http://bioinformatics.charite.de/promiscuous2

Publications:

Publications
More detailed information about this field from each metasource.

PROMISCUOUS: a database for network-based drug-repositioning
PMID: 21071407
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:54.526649

https://doi.org/10.1093/nar/gkaa1061
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

PROMISCUOUS: a database for network-based drug-repositioning PubMed citations: 69.

69 articles citing: PROMISCUOUS: a database for network-based drug-repositioning

NF-κB Signaling and Inflammation-Drug Repurposing to Treat Inflammatory Disorders? PMID:35336746
Strategies to identify candidate repurposable drugs: COVID-19 treatment as a case example. PMID:34785660
A computational study on hydroxychloroquine binding to target proteins related to SARS-COV-2 infection. PMID:34458558
Bioinformatics Accelerates the Major Tetrad: A Real Boost for the Pharmaceutical Industry. PMID:34201152
Drug Repurposing Strategy (DRS): Emerging Approach to Identify Potential Therapeutics for Treatment of Novel Coronavirus Infection. PMID:33718434
Machine learning applications in drug development. PMID:33489002
DrugRepV: a compendium of repurposed drugs and chemicals targeting epidemic and pandemic viruses. PMID:33480398
Artificial Intelligence in Drug Discovery: A Comprehensive Review of Data-driven and Machine Learning Approaches. PMID:33437151
Epidrug Repurposing: Discovering New Faces of Old Acquaintances in Cancer Therapy. PMID:33312959
Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning. PMID:32967266
An up-to-date overview of computational polypharmacology in modern drug discovery. PMID:32452701
The implementation of drug reposition for alcoholic hepatitis based on a sub-pathway integration strategy. PMID:32309355
In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR. PMID:31244651
Drug repositioning of herbal compounds via a machine-learning approach. PMID:31138103
Computational drug repositioning using meta-path-based semantic network analysis. PMID:30598084
In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets. PMID:30596650
Predicting drug-disease associations by using similarity constrained matrix factorization. PMID:29914348
Changing Trends in Computational Drug Repositioning. PMID:29874824
Synthetic Lethality-based Identification of Targets for Anticancer Drugs in the Human Signaling Network. PMID:29855504
DR2DI: a powerful computational tool for predicting novel drug-disease associations. PMID:29687309
Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches. PMID:29186305
A simple mathematical approach to the analysis of polypharmacology and polyspecificity data. PMID:28690829
Entering the 'big data' era in medicinal chemistry: molecular promiscuity analysis revisited. PMID:28670471
Large-Scale Prediction of Drug-Target Interaction: a Data-Centric Review. PMID:28577120
DrugSig: A resource for computational drug repositioning utilizing gene expression signatures. PMID:28562632
Drug repurposing from the perspective of pharmaceutical companies. PMID:28369768
Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning. PMID:28200013
DPDR-CPI, a server that predicts Drug Positioning and Drug Repositioning via Chemical-Protein Interactome. PMID:27805045
Using Big Data to Discover Diagnostics and Therapeutics for Gastrointestinal and Liver Diseases. PMID:27773806
Repurposing FDA-approved drugs for anti-aging therapies. PMID:27484416
Emerging role of bioinformatics tools and software in evolution of clinical research. PMID:27453827
Drug reformulations and repositioning in pharmaceutical industry and its impact on market access: reassessment of nomenclature. PMID:27226826
'RE:fine drugs': an interactive dashboard to access drug repurposing opportunities. PMID:27189611
PDID: database of molecular-level putative protein-drug interactions in the structural human proteome. PMID:26504143
2D and 3D similarity landscape analysis identifies PARP as a novel off-target for the drug Vatalanib. PMID:26403354
A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case. PMID:26100720
Comprehensive prediction of drug-protein interactions and side effects for the human proteome. PMID:26057345
Inferring drug-disease associations based on known protein complexes. PMID:26044949
GraphSAW: a web-based system for graphical analysis of drug interactions and side effects using pharmaceutical and molecular data. PMID:25881043
A survey of current trends in computational drug repositioning. PMID:25832646
Implications of the small number of distinct ligand binding pockets in proteins for drug discovery, evolution and biochemical function. PMID:25690787
Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach. PMID:25525446
On the role of physics and evolution in dictating protein structure and function. PMID:25484448
Drug repurposing and human parasitic protozoan diseases. PMID:25057459
A subpathway-based method of drug reposition for polycystic ovary syndrome. PMID:25015903
Targeting molecular networks for drug research. PMID:24926314
DDI-CPI, a server that predicts drug-drug interactions through implementing the chemical-protein interactome. PMID:24875476
Drug2Gene: an exhaustive resource to explore effectively the drug-target relation network. PMID:24618344
Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation. PMID:24565337
siRNA Genome Screening Approaches to Therapeutic Drug Repositioning. PMID:24275945
Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer. PMID:24135855
DGIdb: mining the druggable genome. PMID:24122041
Target inhibition networks: predicting selective combinations of druggable targets to block cancer survival pathways. PMID:24068907
Open-source approaches for the repurposing of existing or failed candidate drugs: learning from and applying the lessons across diseases. PMID:23966771
Drug repurposing: mining protozoan proteomes for targets of known bioactive compounds. PMID:23757409
Interplay of physics and evolution in the likely origin of protein biochemical function. PMID:23690621
DrugMap Central: an on-line query and visualization tool to facilitate drug repositioning studies. PMID:23681121
Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties. PMID:23550937
Network pharmacology strategies toward multi-target anticancer therapies: from computational models to experimental design principles. PMID:23530504
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. PMID:23384594
ChemProt-2.0: visual navigation in a disease chemical biology database. PMID:23185041
CIDeR: multifactorial interaction networks in human diseases. PMID:22809392
A generalizable pre-clinical research approach for orphan disease therapy. PMID:22704758
ProBiS-2012: web server and web services for detection of structurally similar binding sites in proteins. PMID:22600737
FDA approved drugs complexed to their targets: evaluating pose prediction accuracy of docking protocols. PMID:22562231
Network systems biology for targeted cancer therapies. PMID:22176777
SuperTarget goes quantitative: update on drug-target interactions. PMID:22067455
Integrative computational biology for cancer research. PMID:21691773
Exploiting drug-disease relationships for computational drug repositioning. PMID:21690101
https://doi.org/10.1093/nar/gkaa1061

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other molecular biology databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

drugs and drug design
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

protein interactions
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:54.526649

small molecules
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:54.526649

molecular interactions, pathways and networks
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:54.526649

medicinal chemistry
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:54.526649

drug metabolism
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:54.526649

molecular biology drug protein interaction small molecule molecular interactions, pathways and networks medicinal chemistry drug metabolism

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