Tag: drug metabolism

Drug-related information: medical indications, adverse drug effects, drug metabolism and Gene Ontology terms of the target proteins.

DrugCentral is online drug information that provides information on active ingredients, chemical entities, pharmaceutical products, drug mode of action, indications, and pharmacologic mode of action. DrugCentral monitors FDA, EMA, and PMDA for new dr ...

Cytochrome P450 alleles and drug interactions

KiMoSys is a user-friendly platform that includes a public data repository of relevant published measurements, including metabolite concentrations (time-series and steady-state), flux data, and enzyme measurements in order to build ODE-based kinetic ...

Reframedb is a comprehensive open-access, drug repositioning screening set of 12,000 compounds that was assembled by combining three widely-used commercial drug competitive intelligence databases (Clarivate Integrity, GVK Excelra GoStar and Citeline ...

Protein-protein and drug-protein interactions for studies of drug repositioning

PK-DB an open database for pharmacokinetics information from clinical trials as well as pre-clinical research. The focus of PK-DB is to provide high-quality pharmacokinetics data enriched with the required meta-information for computational modeling ...

> COMMON LINK WITH (PUB. & NAME DIFFERENT) bio.tools/predrbr (DENGLAB.ORG), bio.tools/deepsacon (DENGLAB.ORG), bio.tools/predhs (DENGLAB.ORG) | an integrative cancer drug combination data portal | DrugComb is an open-access, community-driven data por ...

DrugCombDB is a comprehensive database dedicated to integrating drug combinations from various data sources, include 1) high-throughput screening assays of drug combinations, 2) external databases, and 3) manual curations from PubMed literature.

An acronym for the project "A pipeline for the discovery, sustainable production and commercial utilisation of known and novel high-value triterpenes with new or superior biological activities”. This is an EU-funded collaborative project on establish ...

A web resource for dendrimer pharmacokinetics investigation and prediction. Abstract: The development of nanomedicines currently suffers from a lack of efficient tools to predict pharmacokinetic behaviour without relying upon testing in large number ...

Anti-Inflamamtory Compounds Database for drug discovery.

PepTherDia is a database and tool for structural composition analysis of approved peptide therapeutics and diagnostics. Manually curated database containing a searchable list of approved peptide drugs and diagnostic agents. On these compounds, we hav ...

Facilitating drug discovery with enriched comparative data of targeted agents.

A constructing a bilingual website with validated database for Herb and Western medicine interactions using Ginseng, Ginkgo and Dong Quai as examples.

Natural product-based drug combination and its disease-specific molecular regulation.

NICEdrug.ch is a resource allowing systematic and large-scale computational analysis of drug biochemistry (metabolic precursors or prodrugs and metabolic fate or degradation), enzymatic targets, and toxicity in the context of cellular metabolism, i.e ...

DDIEM - Drug Database for inborn errors of metabolism is a database on therapeutic strategies for inborn errors of metabolism. These strategies are classified by mechanism and outcome in DDIEM ontology. DDIEM uses this ontology to categorize the expe ...

A large and continuously updated drug combination database.

A comprehensive and curated portal for translational research.

DrugSimDB is a comprehensive database of multi-modal drug similarity measures by integrating variety of heterogenous datasets.

A database for anti-cancer compounds with targets and side effect profiles.

Web-Based Database and Predictor of Anti-Inflammatory Natural Products.

The Brazilian Compound Library (BraCoLi) a repository of chemical and biological information for drug design.

Knowledgebase of Microbes’ Battling Agents for Therapeutics.

CASTLE (Computational Analysis of SynThetic LEthals) is a collection of synthetic lethal data for various pathogenic organisms, generated computationally. Here, you can find synthetic lethal genes and reactions for more than 70 organisms.

PharmOmics is a A Species- and Tissue-specific Drug Signature Database and Online Tool for Toxicity Prediction and Drug Repurposing. It is a Web server for Identifying Pathological Pathways, Networks, and Key Regulators via Multidimensional Data Inte ...

Applications of the Microphysiology Systems Database for Experimental ADME-Tox and Disease Models | The MPS-Db aggregates MPS data with linked preclinical and clinical databases for analysis in the context of human exposure. Built in tools enable the ...

Exposome of Human Milk across India (ExHuMId) is a curated resource and analysis of exposome of human milk across India.

A Genome-wide Positioning Systems Platform to Catalyze Multi-omics for Alzheimer’s Therapeutic Discovery. A Network-based multi-omics analysis informs Alzheimer's patient care and therapeutic development.