Drug delivery strategy in hepatocellular carcinoma therapy.
PMID:35248060
A community challenge for a pancancer drug mechanism of action inference from perturbational profile data.
PMID:35106508
De novo individualized disease modules reveal the synthetic penetrance of genes and inform personalized treatment regimens.
PMID:34876496
ScaffComb: A Phenotype-Based Framework for Drug Combination Virtual Screening in Large-Scale Chemical Datasets.
PMID:34723439
Identification of miRNA Signature Associated With Erectile Dysfunction in Type 2 Diabetes Mellitus by Support Vector Machine-Recursive Feature Elimination.
PMID:34707644
Prediction and identification of synergistic compound combinations against pancreatic cancer cells.
PMID:34585118
Synergistic Interactions of Cannabidiol with Chemotherapeutic Drugs in MCF7 Cells: Mode of Interaction and Proteomics Analysis of Mechanisms.
PMID:34576262
Machine learning methods, databases and tools for drug combination prediction.
PMID:34477201
Revealing biomarkers associated with PARP inhibitors based on genetic interactions in cancer genome.
PMID:34471490
Comparative analysis of molecular fingerprints in prediction of drug combination effects.
PMID:34401895
Machine learning in the prediction of cancer therapy.
PMID:34377366
Machine learning approaches for drug combination therapies.
PMID:34368832
Metabolomic Identification of Anticancer Metabolites of Australian Propolis and Proteomic Elucidation of Its Synergistic Mechanisms with Doxorubicin in the MCF7 Cells.
PMID:34360606
Artificial intelligence and machine learning methods in predicting anti-cancer drug combination effects.
PMID:34347041
pdCSM-cancer: Using Graph-Based Signatures to Identify Small Molecules with Anticancer Properties.
PMID:34213323
A Systems Approach to Brain Tumor Treatment.
PMID:34202449
Using response surface models to analyze drug combinations.
PMID:34119666
DrugComb update: a more comprehensive drug sensitivity data repository and analysis portal.
PMID:34060634
LigAdvisor: a versatile and user-friendly web-platform for drug design.
PMID:34023895
Utilizing graph machine learning within drug discovery and development.
PMID:34013350
Improved Treatment Outcomes by Using Patient Specific Drug Combinations in Mammalian Target of Rapamycin Activated Advanced Metastatic Cancers.
PMID:33935721
Drug target ranking for glioblastoma multiforme.
PMID:33902757
The Landscape of Signaling Pathways and Proteasome Inhibitors Combinations in Multiple Myeloma.
PMID:33799793
The tumor therapy landscape of synthetic lethality.
PMID:33627666
The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia.
PMID:33597638
Cytotoxicity of Seaweed Compounds, Alone or Combined to Reference Drugs, against Breast Cell Lines Cultured in 2D and 3D.
PMID:33572635
Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry.
PMID:33539432
Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51.
PMID:33531658
Modifying Adaptive Therapy to Enhance Competitive Suppression.
PMID:33260773
canSAR: update to the cancer translational research and drug discovery knowledgebase.
PMID:33219674
CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics.
PMID:33196823
A Middle-Out Modeling Strategy to Extend a Colon Cancer Logical Model Improves Drug Synergy Predictions in Epithelial-Derived Cancer Cell Lines.
PMID:33195403
H-RACS: a handy tool to rank anti-cancer synergistic drugs.
PMID:33173014
Optimized Combination of HDACI and TKI Efficiently Inhibits Metabolic Activity in Renal Cell Carcinoma and Overcomes Sunitinib Resistance.
PMID:33126775
A novel estimator of the interaction matrix in Graphical Gaussian Model of omics data using the entropy of non-equilibrium systems.
PMID:33067612
Anticancer drug synergy prediction in understudied tissues using transfer learning.
PMID:33040150
Graph-based prediction of Protein-protein interactions with attributed signed graph embedding.
PMID:32693790
SYNERGxDB: an integrative pharmacogenomic portal to identify synergistic drug combinations for precision oncology.
PMID:32442307
PaccMann: a web service for interpretable anticancer compound sensitivity prediction.
PMID:32402082
Deep graph embedding for prioritizing synergistic anticancer drug combinations.
PMID:32153729
Charting the Fragmented Landscape of Drug Synergy.
PMID:32113653
Exploration of databases and methods supporting drug repurposing: a comprehensive survey.
PMID:32055842
DrugCombDB: a comprehensive database of drug combinations toward the discovery of combinatorial therapy.
PMID:31665429