Genome-wide DNA methylation patterns reveal clinically relevant predictive and prognostic subtypes in human osteosarcoma.
PMID:35260776
A community challenge for a pancancer drug mechanism of action inference from perturbational profile data.
PMID:35106508
Navigating Multi-Scale Cancer Systems Biology Towards Model-Driven Clinical Oncology and Its Applications in Personalized Therapeutics.
PMID:34900668
Omics- and Pharmacogenomic Evidence for the Prognostic, Regulatory, and Immune-Related Roles of PBK in a Pan-Cancer Cohort.
PMID:34859058
PharmacoDB 2.0: improving scalability and transparency of in vitro pharmacogenomics analysis.
PMID:34850112
The Integrative Analysis of Thrombospondin Family Genes in Pan-Cancer Reveals that THBS2 Facilitates Gastrointestinal Cancer Metastasis.
PMID:34804159
Hsp90-associated DNA replication checkpoint protein and proteasome-subunit components are involved in the age-related macular degeneration.
PMID:34629418
An overview of machine learning methods for monotherapy drug response prediction.
PMID:34619752
RTK25: A Comprehensive Molecular Profiling Strategy in Cholangiocarcinoma Using an Integrated Bioinformatics Approach.
PMID:34577598
A cross-study analysis of drug response prediction in cancer cell lines.
PMID:34524425
Drug sensitivity prediction from cell line-based pharmacogenomics data: guidelines for developing machine learning models.
PMID:34382071
Machine learning in the prediction of cancer therapy.
PMID:34377366
Interpretable deep recommender system model for prediction of kinase inhibitor efficacy across cancer cell lines.
PMID:34362938
A Personalized Therapeutics Approach Using an In Silico Drosophila Patient Model Reveals Optimal Chemo- and Targeted Therapy Combinations for Colorectal Cancer.
PMID:34336681
Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia.
PMID:34302041
Evidence of Omics, Immune Infiltration, and Pharmacogenomic for SENP1 in the Pan-Cancer Cohort.
PMID:34276383
Integrative analysis the characterization of peroxiredoxins in pan-cancer.
PMID:34246267
Thunor: visualization and analysis of high-throughput dose-response datasets.
PMID:34038546
Artificial Intelligence in Cancer Research and Precision Medicine.
PMID:33811123
Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs.
PMID:33767176
Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor.
PMID:33750001
The Aurora kinase/β-catenin axis contributes to dexamethasone resistance in leukemia.
PMID:33597638
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML.
PMID:33594052
Multiobjective optimization identifies cancer-selective combination therapies.
PMID:33370253
CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics.
PMID:33196823
DORGE: Discovery of Oncogenes and tumoR suppressor genes using Genetic and Epigenetic features.
PMID:33177077
Universal Nature of Drug Treatment Responses in Drug-Tissue-Wide Model-Animal Experiments Using Tensor Decomposition-Based Unsupervised Feature Extraction.
PMID:32973862
Targeted inhibition of KDM6 histone demethylases eradicates tumor-initiating cells via enhancer reprogramming in colorectal cancer.
PMID:32929331
RNA Sequencing of Hepatobiliary Cancer Cell Lines: Data and Applications to Mutational and Transcriptomic Profiling.
PMID:32899426
The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma.
PMID:32665698
AITL: Adversarial Inductive Transfer Learning with input and output space adaptation for pharmacogenomics.
PMID:32657371
Machine learning approaches to drug response prediction: challenges and recent progress.
PMID:32566759
Towards the routine use of in silico screenings for drug discovery using metabolic modelling.
PMID:32369553
Mining Drug-Target Associations in Cancer: Analysis of Gene Expression and Drug Activity Correlations.
PMID:32344870
The pan-cancer landscape of netrin family reveals potential oncogenic biomarkers.
PMID:32251318
Optimization of cell viability assays to improve replicability and reproducibility of cancer drug sensitivity screens.
PMID:32242081
Computational Methods for the Integrative Analysis of Genomics and Pharmacological Data.
PMID:32175273
MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma.
PMID:32157112
Exploring Integrative Analysis Using the BioMedical Evidence Graph.
PMID:32097025
Exploration of databases and methods supporting drug repurposing: a comprehensive survey.
PMID:32055842
Synergy between Non-Thermal Plasma with Radiation Therapy and Olaparib in a Panel of Breast Cancer Cell Lines.
PMID:32033118
A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells.
PMID:32029739
A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin.
PMID:31660150
A Humanized Yeast Phenomic Model of Deoxycytidine Kinase to Predict Genetic Buffering of Nucleoside Analog Cytotoxicity.
PMID:31575041
Creating reproducible pharmacogenomic analysis pipelines.
PMID:31481707
Gene Expression Analyses in Breast Cancer: Sample Matters.
PMID:31360851
In Silico Toxicology Data Resources to Support Read-Across and (Q)SAR.
PMID:31244651
Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer.
PMID:31107860
Combined Minimum-Run Resolution IV and Central Composite Design for Optimized Removal of the Tetracycline Drug Over Metal⁻Organic Framework-Templated Porous Carbon.
PMID:31100932
Encircling the regions of the pharmacogenomic landscape that determine drug response.
PMID:30914058
Dr.VAE: improving drug response prediction via modeling of drug perturbation effects.
PMID:30850846
A Comparative Study of Cluster Detection Algorithms in Protein-Protein Interaction for Drug Target Discovery and Drug Repurposing.
PMID:30837876
Free Accessible Databases as a Source of Information about Food Components and Other Compounds with Anticancer Activity⁻Brief Review.
PMID:30813234
Use of Germline Genetic Variability for Prediction of Chemoresistance and Prognosis of Breast Cancer Patients.
PMID:30545124
Cell Model Passports-a hub for clinical, genetic and functional datasets of preclinical cancer models.
PMID:30260411
More than fishing for a cure: The promises and pitfalls of high throughput cancer cell line screens.
PMID:29953899