Tag: biomarkers

The IEDB provides the scientific community with a central repository of freely accessible epitope data and epitope prediction and analysis resources. The IEDB is a publicly accessible, comprehensive immune epitope database containing peptidic linear ...

The Chemical Effects in Biological Systems (CEBS) database houses data of interest to environmental health scientists. CEBS is a public resource, and has received depositions of data from academic, industrial, and governmental laboratories.

The ITHANET Portal represents an expanding resource for clinicians and researchers dealing with haemoglobinopathies and a port of call for patients in search of professional advice. The ITHANET Portal integrates information on news, events, clinical ...

UK Biobank is a large-scale biomedical database and research resource that provides researchers access to detailed longitudinal phenotype, medical and genetic data from 500,000 volunteer participants.

Recent cancer pharmacogenomic studies profiled large panels of cell lines against hundreds of approved drugs and experimental chemical compounds. The overarching goal of these screens is to measure sensitivity of cell lines to chemical perturbations, ...

Biomarkers of exposure to disease risk factors

A manually-curated database of experimentally-supported functional lncRNA-target regulations in human diseases. Search and download the information for the Mutual exclusivity. MutExGenome is a database of Mutual Exclusive mutations in mutiple specie ...

Biomarkers: chemical, protein, chromosomal and genetic

Inborn Errors of Metabolism Knowledgebase (IEMbase) accepts an array of biochemical and clinical symptoms from a user and returns a ranked list of possible IEM disorders that match the input profile. In addition, the system can explain the rationale ...

FOBI (Food-Biomarker Ontology) is an ontology to represent food intake data and associate it with metabolomic data.

An atlas of mRNA, lncRNA and circRNA in extracellular vesicles from human biofluids.

StackIL6 is a stacking ensemble model for improving the prediction of IL-6 inducing peptides.

CIViCmine is a literature-mined database of clinically relevant cancer biomarkers from data from PubMed and Pubmed Central Open Access subset.

the small RNA Expression Atlas web application. Sign in with Google or with you SEA account below. If you have not created an account yet, then please register first. If you have received an eMail from Oasis 2 that the classification or DE analysis ...

a comprehensive database platform for identification and validation of disease related noncoding RNAs. Mar 26, 2020: ncRPheno was published on the journal of RNA Biology... ncRPheno is a comprehensive database that provides experimentally supported ...

circad is a comprehensive manually curated resource of circular RNA associated with diseases. Circular RNAs (circRNAs) are unique transcript isoforms characterised by back splicing of exon ends to form a covalently closed loop or circular conformatio ...

A human immunosuppression gene database. HisgAtlas is the first database that stores a list of immunosuppression genes collected by literature mining and manual curation. 995 human immunosuppression genes and 260 associated diseases are collected in ...

Predicting circRNA-Disease Associations Based on Improved Collaboration Filtering Recommendation System With Multiple Data. March 31, 2018, the CircR2Disease has been updated. Circular RNAs (circRNAs) are widely expressed in diverse eukaryotic spec ...

a curated database for intrapatient tumor heterogeneity. CancerTracer is a manually curated and integrated database aims to help researchers to decipher tumor heterogeneity at individual patient level. It contains two types of tumor heterogeneity da ...

Tissue-specific circRNA expression profiles and regulatory networks

A manually curated database for experimentally supported lncRNAs during various cancer metastatic events. A database for experimentally supported lncRNAs during various cancer metastatic events.

Database for ncRNA expression in human extracellular vesicles.

A Manually Curated Database for Identification of Noncoding RNA Variants Associated with Human Diseases. Jun 1, 2018: Startup of the ncRNAVar project.... Sep 10, 2019: The variant mapping was developed...

Genetic Interaction-Based Biomarkers Identification for Drug Resistance and Sensitivity in Cancer Cells | Cancer cells generally harbor hundreds of alterations in the cancer genomes and act as crucial factors in the development and progression of can ...

CancerLivER (Liver Cancer Expression Resource) is a database of liver cancer that maintains gene expression datasets and biomarkers curated from public repositories and literature respectively. It contains the following three modules for extracting a ...

Human osteoporosis-related gene database.

A database of cancer associated enhancers. A comprehensive resource on enhancer information for TCGA cancer types. CancerEnD Genome-wide association studies have successfully identified thousands of genomic loci potentially associated with hundreds ...

A database of Plant Chloroplast Inverted Repeats. Plant Chloroplast Inverted Repeats. Welcome to PCIR! Plant Chloroplast Inverted Repeats (PCIR) is an interactive, web-based platform containing various sequenced chloroplast genomes that enables det ...

dBMHCC is a comprehensive hepatocellular carcinoma (HCC) biomarker database provides a reliable prediction system for novel HCC phosphorylated biomarkers.

An online transcriptome platform for human circRNA expressions in cancers.

CMBD (Cancer Metabolic Biomarker knowledge Database) a manually curated cancer metabolic biomarker knowledge database.

CMTTdb (The Cancer Molecular-Targeted Therapy database) is an integrated database to store relevant information about molecular targeted agents as well as their combinatorial approaches in clinical trials and studies for cancer treatment. It contains ...

TTSurv aims to correlate coding and noncoding genes with cancers by combining high-throughput data with clinical prognosis. The application focuses on the use of high-throughput data to detect ncRNAs, such as lncRNAs and microRNAs, as novel diagnosti ...

A biomarker knowledge database for heart failure heterogeneity and personalized applications.

Engrailed 1 overexpression as a potential prognostic marker in Lower Grade Glioma.

ExoBCD is a comprehensive database for exosomal biomarker discovery in breast cancer.

An integrative analysis platform for investigating differentially expressed gene-level and isoform-level human cancer markers

CRMarker is a manually curated comprehensive resource of both long noncoding and circular cancer RNA markers.

An Alzheimer's Disease Biomarker Comprehensive Database for Humans. It includes the information for all the genetic parameters like mitochondrial genes, polymorphic genes (SNP's), transcription factors, proteins, miRNAs, Associative pathway, and AD b ...

Cancer Treatment Response gene signature DataBase (CTR-DB). A database for basic and clinical researchers to access, integrate, and reuse clinical transcriptomes with cancer drug response.

A Literature-Curated Database of microRNA Expression Patterns, in Diabetic Microvascular Complications. miR2Diabetes aims to provide a comprehensive resource of miRNA dysregulation in diabetic microvascular complications (DMC). Each entry in the miR2 ...

Deeply phenotyped data on COVID-19 hospital patients with multi-morbidities requiring/at risk of requiring ventilatory support: This includes investigations, with serial biomarkers, ITU spells, interventions undertaken and outcomes.

Longitudinal routine data for 128,000 admissions to hospital as an emergency from a care home; including treatments, interventions, ITU admissions and outcomes. Deeply phenotyped longitudinal data including serial physiology, blood biomarkers.

Prospective, longitudinal cohort of patients with community liver disease. Patients selected by risk factors and followed for long term clinical outcomes.

A Prospective, observational, single centre cohort study of patients with compensated cirrhosis. Patients have been longitudinally followed for the development of clinical outcomes and have serial bio-samples and some detailed imaging including MRI d ...

Hosp patients admitted during COVID pandemic with coagulopathies including venous thromboembolic events & bleeds. Granular condition, multi-morbidity, interventions & treatments. Serial physiology, blood biomarkers, ITU spells, outcome. Deeply phenot ...

Patients admitted with a bleeding or clotting disorder. Granular care pathways. Multi-morbidity, investigations, interventions and treatments. Serial physiology, blood biomarkers, physiotherapy, outcome. Deeply phenotyped. Risk and outcomes of coag ...

Comparing the features of people with fatty liver (NASH/ASH) to those of people with no disease with the aim to develop new non-invasive tests to diagnose fatty liver disease, NASH/ASH and predict disease progression, as an alternative to liver biops ...

Hospital patients admitted during the COVID pandemic requiring/at risk of requiring ventilatory support. Granular condition, multi-morbidity, interventions and treatments. Serial physiology, blood biomarkers, ITU spells, outcome. Deeply phenotyped ...

Hospital patients admitted during the COVID pandemic with a focus on COPD. Granular condition, multi-morbidity. Serial physiology, blood biomarkers, treatments, interventions, ITU spells, outcome, pre/post admission healthcare use. Deeply phenotyped ...

Patients admitted with a COPD related event. Granular care pathways. Multi-morbidity, investigations, interventions and treatments. Serial physiology, blood biomarkers, physiotherapy, outcome. Deeply phenotyped. The impact of hospitalised patients ...

Hospital patient acuity scores (2004 onwards). Granular condition, ethnicity, multi-morbidity. Serial physiology, blood biomarkers, treatments, interventions, ITU spells, outcome, pre/post admission healthcare use. Deeply phenotyped, longitudinal. C ...

Hospital COVID patients 6.01.2020-20.08.2020). Granular severity, ethnicity, co-morbidity. Serial acuity, physiology, blood biomarkers, treatments, ITU, outcome. Deeply phenotyped, longitudinal. OMOP dataset: Hospital COVID patients: severity, acuit ...

A deeply phenotyped dataset of hospitalised COVID-19 patients in Birmingham; including granular ethnicity and multi-morbidity data confirmed in primary care; physiology, blood biomarkers, treatments, interventions, ITU admissions and outcomes. PIONEE ...

Hospital COVID patients (6th Jan 2020 onwards). Granular severity, ethnicity, co-morbidity. Serial physiology, blood biomarkers, images, treatments, ITU, outcome, pre/post admission healthcare use. Deeply phenotyped, longitudinal. Waves 1/ 2 PIONEER ...

A granular dataset of over 65,000 emergency admissions, with detailed patient flow through hospital detailing day-to-day variation in case mix. Severity, demographics, multi-morbidity, completion of review, interventions, treatments and outcomes.

Mechanical and non-invasive ventilation, tracheostomy. Ventilator settings, tidal volumes and pressures. ECMO, inotropes, other organ support, medications, investigations and serial physiology. The preceding care journey and outcomes Ventilatory stra ...

Society of Acute Medicine Audit data. Hospital patients admitted during the COVID pandemic. Granular care pathways for reconfigured services. Severity, demographics, multi-morbidity, interventions and treatments, outcomes. Flow through hospital. UHBF ...

Society of Acute Medicine Audit data. Hospital patients. Granular care pathways against national guidelines. Severity, demographics, multi-morbidity, completion of review, interventions and treatments, outcomes. Patient flow through hospital. UHBFT B ...

LBD (Lymphoma Biomarker Database) is a manually curated database of literature-supported biomarkers for lymphoma. It contains 793 biomarkers (715 single biomarkers and 78 combined biomarkers) for different subtypes of lymphoma which have been verifie ...

An Interactive Web Server to Evaluate Prognostic Biomarkers for Ovarian Cancer.

Multi-omics molecular biomarkers and database of osteoarthritis.

A database of manually curated biomarkers for Prostate Cancer.

A database of biomarkers of cancer stem cells.

Database for identification of cancer immunotherapies associating with biomarkers, targets, and clinical effects

BDdb is a comprehensive database associated with birth-defect-related diseases. It consists of multi-omics datasets involving tens of common birth-defect diseases, and BDdb supplements more than 2000 biomarkers belonging to 22 types of birth defects.

Essential Features and Use Cases of the Cerebrospinal Fluid Proteome Resource (CSF-PR) | Every year, a large number of published studies present biomarkers for various neurological disorders. Many of these studies are based on mass spectrometry prote ...

The two decades brainclinics research archive for insights in neurophysiology (TDBRAIN) database.

A unified database and server platform for muscle atrophy myomiRs, coregulatory networks and regulons. A Database of miRNAs during Muscular Atrophy. Defence Institute of Physiology and Allied Sciences,.

The Integrated Aging Studies Databank and Repository (IASDR) IASDR serves as a resource for the scientific community to foster new scientific questions and analyses

exRNADisease is a database designed for providing the landscape of different types of extracellular RNAs (mRNAs, lncRNAs, miRNAs, circRNAs, tRFRNAs and piRNAs) from body fluids in human diseases.

mapMECFS is an interactive data portal providing access to research results across many biological disciplines from studies that are focused on advancing our understanding of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS).

The Lung Cancer Metabolome Database (LCMD), a freely available online database depositing 2013 lung cancer-related metabolites identified from 65 mass spectrometry-based lung cancer metabolomics studies.

An integrated resource for High-Altitude associated genes and proteins, interacting networks and semantic-similarities. Around 140 million people live in High Altitude (HA) conditions and even a larger number visit it for tourism, adventure-seeking ...

CancerMIRNome is a web server for cancer miRNome interactive analysis and visualization based on the huamn miRNome data of 33 cancer types from The Cancer Genome Atlas (TCGA), and 40 public cancer circulating miRNome profiling datasets from NCBI Gene ...

High performance search engine for gene expression. It integrates thousands of manually curated, well described public microarray and RNAseq experiments and nicely visualizes gene expression across different biological contexts such as diseases, drug ...

Molecular Prognostic Indicators in Cirrhosis Database for Clinical Context-Specific in Silico Prognostic Biomarker Validation. Molecular Prognostic Indicators in Cirrhosis. Database for clinical context-specific in silico prognostic biomarker valid ...

A Server Platform For High Altitude Human miRNA-Gene Coregulatory Networks And Associated Regulatory-Circuits. HAHmiR DB (High-Altitude Human miRNA Database) is a unique, comprehensive, curated collection of miRNAs that have been experimentally vali ...

The BIONDA biomarker database provides structured information on all biomarker candidates published in PubMed articles. There is no limitation to any kind of diseases. To this end, PubMed article abstracts and renowned databases such as UniProt and H ...

Project Achilles is a systematic effort aimed at identifying and cataloging genetic vulnerabilities across hundreds of genomically characterized cancer cell lines. The project uses genome-wide genetic perturbation reagents (shRNAs or Cas9/sgRNAs) to ...