WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs
Names
More detailed information about this field from each metasource.
WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs
metasource: Fairsharing.org
version: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
WITHDRAWN
metasource: Fairsharing.org
version: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Names
More detailed information about this field from each metasource.
WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
WITHDRAWN
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Names
More detailed information about this field from each metasource.
WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
WITHDRAWN
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
This source may no longer be available. No known URL could be resolved successfully.
WITHDRAWN is a database of withdrawn and discontinued drugs that were recalled from global markets due to safety concerns. The database serves as a useful resource with information about the therapeutic (or primary) targets, off-targets, toxicity types and biological pathways associated with the drugs in the database. Furthermore, genetic variations (SNPs) associated with the therapeutic and off-targets are presented within to shed light on the common genetic variations that could lead to toxicity and thereby to drug withdrawal or discontinuation in specific populations.
Description
More detailed information about this field from each metasource.
WITHDRAWN is a database of withdrawn and discontinued drugs that were recalled from global markets due to safety concerns. The database serves as a useful resource with information about the therapeutic (or primary) targets, off-targets, toxicity types and biological pathways associated with the drugs in the database. Furthermore, genetic variations (SNPs) associated with the therapeutic and off-targets are presented within to shed light on the common genetic variations that could lead to toxicity and thereby to drug withdrawal or discontinuation in specific populations.
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Withdrawn and discontinued drugs
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Webpage:
http://cheminfo.charite.de/withdrawn/Webpage
More detailed information about this field from each metasource.
http://cheminfo.charite.de/withdrawn/
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://cheminfo.charite.de/withdrawn
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Publications:
Publications
More detailed information about this field from each metasource.
WITHDRAWN--a resource for withdrawn and discontinued drugs
PMID: 26553801
metasource: Fairsharing.org
version: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://dx.doi.org/10.1093/nar/gkv1192
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
WITHDRAWN--a resource for withdrawn and discontinued drugs
PMID: 26553801
metasource: Fairsharing.org
version: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://dx.doi.org/10.1093/nar/gkv1192
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
-
WITHDRAWN--a resource for withdrawn and discontinued drugs
PubMed citations: 63.
63 articles citing: WITHDRAWN--a resource for withdrawn and discontinued drugs
Spontaneous adverse drug reaction reporting by community pharmacists: preparedness and barriers. PMID:35903525
Comparison of Drug Withdrawal Processes in the U.S. and Other Nations. PMID:35601589
Long-Term Electrical and Mechanical Function Monitoring of a Human-on-a-Chip System. PMID:35586798
An Explainable Supervised Machine Learning Model for Predicting Respiratory Toxicity of Chemicals Using Optimal Molecular Descriptors. PMID:35456666
Simultaneous triple-parametric optical mapping of transmembrane potential, intracellular calcium and NADH for cardiac physiology assessment. PMID:35388167
High-Throughput Chemical Screening and Structure-Based Models to Predict hERG Inhibition. PMID:35205076
Essential oil from Cymbopogon citratus exhibits "anti-aspergillosis" potential: in-silico molecular docking and in vitro studies. PMID:35125860
Risk for Postmarket Black Box Warnings in FDA-Approved Monoclonal Antibodies. PMID:35024565
Zebrafish Embryos and Larvae as Alternative Animal Models for Toxicity Testing. PMID:34948215
DrugEx v2: de novo design of drug molecules by Pareto-based multi-objective reinforcement learning in polypharmacology. PMID:34772471
Path4Drug: Data Science Workflow for Identification of Tissue-Specific Biological Pathways Modulated by Toxic Drugs. PMID:34721010
Blood Neurofilament Light Chain as a Potential Biomarker for Central and Peripheral Nervous Toxicity in Rats. PMID:34677616
Impacts of diphenylamine NSAID halogenation on bioactivation risks. PMID:34107285
Assessing Consistency Across Functional Screening Datasets in Cancer Cells. PMID:34081116
Engineering Cardiovascular Tissue Chips for Disease Modeling and Drug Screening Applications. PMID:33959600
The Promise of AI for DILI Prediction. PMID:33937745
Human Induced Pluripotent Stem Cells as a Screening Platform for Drug-Induced Vascular Toxicity. PMID:33790786
A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology Studies. PMID:33732695
Chemical Aspects of Human and Environmental Overload with Fluorine. PMID:33723999
Zebrafish: An emerging whole-organism screening tool in safety pharmacology. PMID:33666192
Combining In Vivo Data with In Silico Predictions for Modeling Hepatic Steatosis by Using Stratified Bagging and Conformal Prediction. PMID:33347274
Effects of Cryopreservation on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Assessing Drug Safety Response Profiles. PMID:33338435
Human biomimetic liver microphysiology systems in drug development and precision medicine. PMID:33335282
Network integration and modelling of dynamic drug responses at multi-omics levels. PMID:33060801
From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery. PMID:32848750
From Human Pluripotent Stem Cells to 3D Cardiac Microtissues: Progress, Applications and Challenges. PMID:32785039
In silico prediction of chemical neurotoxicity using machine learning. PMID:32670548
h-FIBER: Microfluidic Topographical Hollow Fiber for Studies of Glomerular Filtration Barrier. PMID:32607437
Nanotoxicology and Nanosafety: Safety-By-Design and Testing at a Glance. PMID:32605255
One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility. PMID:32464151
Harnessing the power of novel animal-free test methods for the development of COVID-19 drugs and vaccines. PMID:32447523
Comparing Machine Learning Algorithms for Predicting Drug-Induced Liver Injury (DILI). PMID:32422053
Limitations of Animal Studies for Predicting Toxicity in Clinical Trials: Part 2: Potential Alternatives to the Use of Animals in Preclinical Trials. PMID:32363250
Production of Human Pluripotent Stem Cell-Derived Hepatic Cell Lineages and Liver Organoids: Current Status and Potential Applications. PMID:32283585
Limitations of Animal Studies for Predicting Toxicity in Clinical Trials: Is it Time to Rethink Our Current Approach? PMID:31998852
In silico analysis of alternative splicing on drug-target gene interactions. PMID:31924844
Evidence to Support Inclusion of Pharmacogenetic Biomarkers in Randomised Controlled Trials. PMID:31480618
Engineered Cardiac Tissues Generated in the Biowire™ II: A Platform for Human-Based Drug Discovery. PMID:31385592
Comparison of zebrafish larvae and hiPSC cardiomyocytes for predicting drug induced cardiotoxicity in humans. PMID:31359052
Herb-Induced Liver Injury: Phylogenetic Relationship, Structure-Toxicity Relationship, and Herb-Ingredient Network Analysis. PMID:31349548
Subchronic and chronic toxicity evaluation of inorganic nanoparticles for delivery applications. PMID:31295521
ADMET-score - a comprehensive scoring function for evaluation of chemical drug-likeness. PMID:30774861
A Comprehensive Map of FDA-Approved Pharmaceutical Products. PMID:30563197
Comparison of Quantitative and Qualitative (Q)SAR Models Created for the Prediction of Ki and IC50 Values of Antitarget Inhibitors. PMID:30364128
Cardiovascular disease models: A game changing paradigm in drug discovery and screening. PMID:30343824
Drug Repurposing Prediction for Immune-Mediated Cutaneous Diseases using a Word-Embedding-Based Machine Learning Approach. PMID:30342048
Topological alternate centrality measure capturing drug targets in the network of MAPK pathways. PMID:30259868
Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system. PMID:30130706
A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents. PMID:30103549
Intact Cell Lipidomics Reveal Changes to the Ratio of Cardiolipins to Phosphatidylinositols in Response to Kanamycin in HeLa and Primary Cells. PMID:29947513
ProTox-II: a webserver for the prediction of toxicity of chemicals. PMID:29718510
Manipulation-free cultures of human iPSC-derived cardiomyocytes offer a novel screening method for cardiotoxicity. PMID:29620051
Investigation assessing the publicly available evidence supporting postmarketing withdrawals, revocations and suspensions of marketing authorisations in the EU since 2012. PMID:29362275
Have the Findings from Clinical Risk Prediction and Trials Any Key Messages for Safety Pharmacology? PMID:29163223
SuperDRUG2: a one stop resource for approved/marketed drugs. PMID:29140469
Self-contained, low-cost Body-on-a-Chip systems for drug development. PMID:29065797
Natural products modulating the hERG channel: heartaches and hope. PMID:28497823
Mouse Models for Drug Discovery. Can New Tools and Technology Improve Translational Power? PMID:28053071
The ChEMBL database in 2017. PMID:27899562
Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come? PMID:27641943
A k-nearest neighbor classification of hERG K(+) channel blockers. PMID:26860111
Post-marketing withdrawal of 462 medicinal products because of adverse drug reactions: a systematic review of the world literature. PMID:26843061
The 2016 database issue of Nucleic Acids Research and an updated molecular biology database collection. PMID:26740669 - http://dx.doi.org/10.1093/nar/gkv1192
Tags:
Tags
More detailed information about this field from each metasource.
drug
metasource: Fairsharing.org
version: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
drug metabolic process
metasource: Fairsharing.org
version: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
drug report
metasource: Fairsharing.org
version: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
target
metasource: Fairsharing.org
version: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
toxicity
metasource: Fairsharing.org
version: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
other molecular biology databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
drugs and drug design
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Tags
More detailed information about this field from each metasource.
drug
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
drug metabolic process
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
drug report
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
target
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
toxicity
metasource: Fairsharing.orgversion: FAIRsharing.org: WITHDRAWN; WITHDRAWN: A Resource for Withdrawn and Discontinued Drugs; DOI: https://doi.org/10.25504/FAIRsharing.OTYQFw; Last edited: April 30, 2019, 2:11 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
other molecular biology databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
drugs and drug design
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
drug drug metabolic process drug report target toxicity molecular biology drug
Need help integrating and/or managing biomedical data?