R3R044 last accessed: 2022-11-04

European Hepatitis C virus database (euHCVdb)
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:16.291264

euhcvdb
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:16.291264

Other names: euHCVdb, european Hepatitis C Virus database, european hepatitis C virus sequences database, European Hepatitis C virus database (euHCVdb), euhcvdb

The euHCVdb is mainly oriented towards protein sequence, structure and function analyses and structural biology of Hepatitis C Virus.

Webpage:

http://euhcvdb.ibcp.fr/euHCVdb/

Licence:

Name: Open Data Commons (ODC) Public Domain Dedication and Licence (PDDL) 1.0
URL: http://opendatacommons.org/licenses/pddl/1.0/

Publications:

Publications
More detailed information about this field from each metasource.

euHCVdb: the European hepatitis C virus database
PMID: 17142229
metasource: Fairsharing.org
version: FAIRsharing.org: euHCVdb; European Hepatitis C Virus database; DOI: https://doi.org/10.25504/FAIRsharing.bwctv; Last edited: June 23, 2021, 10:14 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

The euHCVdb suite of in silico tools for investigating the structural impact of mutations in hepatitis C virus proteins
PMID: 19519481
metasource: Fairsharing.org
version: FAIRsharing.org: euHCVdb; European Hepatitis C Virus database; DOI: https://doi.org/10.25504/FAIRsharing.bwctv; Last edited: June 23, 2021, 10:14 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

http://dx.doi.org/10.1093/nar/gkl970
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:16.291264

euHCVdb: the European hepatitis C virus database PubMed citations: 83.

83 articles citing: euHCVdb: the European hepatitis C virus database

Sheet, Surveillance, Strategy, Salvage and Shield in global biodefense system to protect the public health and tackle the incoming pandemics. PMID:35093353
An Antigenically Diverse, Representative Panel of Envelope Glycoproteins for Hepatitis C Virus Vaccine Development. PMID:34655573
HCV genome-wide analysis for development of efficient culture systems and unravelling of antiviral resistance in genotype 4. PMID:33833066
Automated, phylogeny-based genotype delimitation of the Hepatitis Viruses HBV and HCV. PMID:31667012
Cyclophilin A allows the allosteric regulation of a structural motif in the disordered domain 2 of NS5A and thereby fine-tunes HCV RNA replication. PMID:31315928
Near-Neighbor Interactions in the NS3-4A Protease of HCV Impact Replicative Fitness of Drug-Resistant Viral Variants. PMID:31051172
Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A. PMID:28231271
Identification of Novel Functions for Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly. PMID:28179528
Protein Bioinformatics Databases and Resources. PMID:28150231
A Point Mutation in the N-Terminal Amphipathic Helix α0 in NS3 Promotes Hepatitis C Virus Assembly by Altering Core Localization to the Endoplasmic Reticulum and Facilitating Virus Budding. PMID:28053108
HCVIVdb: The hepatitis-C IRES variation database. PMID:27527702
Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins. PMID:27198619
Sequencing Analysis of NS3/4A, NS5A, and NS5B Genes from Patients Infected with Hepatitis C Virus Genotypes 5 and 6. PMID:27147726
Common molecular mechanism of the hepatic lesion and the cardiac parasympathetic regulation in chronic hepatitis C infection: a critical role for the muscarinic receptor type 3. PMID:27000565
Comprehensive Screening for Naturally Occurring Hepatitis C Virus Resistance to Direct-Acting Antivirals in the NS3, NS5A, and NS5B Genes in Worldwide Isolates of Viral Genotypes 1 to 6. PMID:26856832
Natural HCV variants with increased replicative fitness due to NS3 helicase mutations in the C-terminal helix α18. PMID:26787124
Analysis of Hepatitis C Virus Genotype 1b Resistance Variants in Japanese Patients Treated with Paritaprevir-Ritonavir and Ombitasvir. PMID:26643326
Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance. PMID:26392503
Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion. PMID:26246575
NS5A Sequence Heterogeneity and Mechanisms of Daclatasvir Resistance in Hepatitis C Virus Genotype 4 Infection. PMID:26170396
Resistance analysis of baseline and treatment-emergent variants in hepatitis C virus genotype 1 in the AVIATOR study with paritaprevir-ritonavir, ombitasvir, and dasabuvir. PMID:26100711
A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein Is Essential for Hepatitis C Virus RNA Replication. PMID:26085105
In vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitor. PMID:25534735
Hepatitis C virus genotype 7, a new genotype originating from central Africa. PMID:25520447
In vitro and in vivo antiviral activity and resistance profile of ombitasvir, an inhibitor of hepatitis C virus NS5A. PMID:25451055
Unraveling the web of viroinformatics: computational tools and databases in virus research. PMID:25428870
Aminoterminal amphipathic α-helix AH1 of hepatitis C virus nonstructural protein 4B possesses a dual role in RNA replication and virus production. PMID:25392992
Comparison of daclatasvir resistance barriers on NS5A from hepatitis C virus genotypes 1 to 6: implications for cross-genotype activity. PMID:24936600
NS2 proteins of GB virus B and hepatitis C virus share common protease activities and membrane topologies. PMID:24741107
Hepatitis C virus NS5A inhibitors and drug resistance mutations. PMID:24659881
BCL2DB: database of BCL-2 family members and BH3-only proteins. PMID:24608034
Evolution of a cell culture-derived genotype 1a hepatitis C virus (H77S.2) during persistent infection with chronic hepatitis in a chimpanzee. PMID:24429362
Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug. PMID:24419349
Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource. PMID:24115039
Identification of alpha interferon-induced envelope mutations of hepatitis C virus in vitro associated with increased viral fitness and interferon resistance. PMID:24049176
Persistence of resistant variants in hepatitis C virus-infected patients treated with the NS5A replication complex inhibitor daclatasvir. PMID:23403428
Intragenic complementation of hepatitis C virus NS5A RNA replication-defective alleles. PMID:23236071
Disulfide bonds in hepatitis C virus glycoprotein E1 control the assembly and entry functions of E2 glycoprotein. PMID:23175356
Resistance studies of a dithiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems. PMID:23165461
Structural and molecular basis of interaction of HCV non-structural protein 5A with human casein kinase 1α and PKR. PMID:23148689
HBVdb: a knowledge database for Hepatitis B Virus. PMID:23125365
In vitro activity of daclatasvir on hepatitis C virus genotype 3 NS5A. PMID:23089758
Two crucial early steps in RNA synthesis by the hepatitis C virus polymerase involve a dual role of residue 405. PMID:22532694
Base pairing between hepatitis C virus RNA and microRNA 122 3' of its seed sequence is essential for genome stabilization and production of infectious virus. PMID:22532678
Ketoamide resistance and hepatitis C virus fitness in val55 variants of the NS3 serine protease. PMID:22252823
Hepatitis C virus RNA elimination and development of resistance in replicon cells treated with BMS-790052. PMID:22214777
In vitro activity of BMS-790052 on hepatitis C virus genotype 4 NS5A. PMID:22203595
Peptidomimetic escape mechanisms arise via genetic diversity in the ligand-binding site of the hepatitis C virus NS3/4A serine protease. PMID:22155364
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor. PMID:22006008
Naturally occurring genotype 2b/1a hepatitis C virus in the United States. PMID:21967740
Transmission of clonal hepatitis C virus genomes reveals the dominant but transitory role of CD8⁺ T cells in early viral evolution. PMID:21900166
Development and application of hepatitis C reporter viruses with genotype 1 to 7 core-nonstructural protein 2 (NS2) expressing fluorescent proteins or luciferase in modified JFH1 NS5A. PMID:21697486
Distinct functions of NS5A in hepatitis C virus RNA replication uncovered by studies with the NS5A inhibitor BMS-790052. PMID:21593143
Regulation of the production of infectious genotype 1a hepatitis C virus by NS5A domain III. PMID:21525356
Domain 3 of NS5A protein from the hepatitis C virus has intrinsic alpha-helical propensity and is a substrate of cyclophilin A. PMID:21489988
Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly. PMID:21187906
Identification of new functional regions in hepatitis C virus envelope glycoprotein E2. PMID:21147916
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A. PMID:21060866
NMR structure and ion channel activity of the p7 protein from hepatitis C virus. PMID:20667830
Resistance analysis of the hepatitis C virus NS5A inhibitor BMS-790052 in an in vitro replicon system. PMID:20585111
Co-lethality studied as an asset against viral drug escape: the HIV protease case. PMID:20565756
Dimerization of the hepatitis C virus nonstructural protein 4B depends on the integrity of an aminoterminal basic leucine zipper. PMID:20506268
Enhanced protocol for determining the 3' terminus of hepatitis C virus. PMID:20381536
Contribution of charged and polar residues for the formation of the E1-E2 heterodimer from Hepatitis C Virus. PMID:20195665
Virological footprint of CD4+ T-cell responses during chronic hepatitis C virus infection. PMID:20107020
Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics. PMID:19680534
The evolution of the major hepatitis C genotypes correlates with clinical response to interferon therapy. PMID:19668364
Low pH-dependent hepatitis C virus membrane fusion depends on E2 integrity, target lipid composition, and density of virus particles. PMID:19411248
Identification of a novel determinant for membrane association in hepatitis C virus nonstructural protein 4B. PMID:19357161
Seroconversion to hepatitis C virus alternate reading frame protein during acute infection. PMID:19350656
Hepatitis C virus NS5A protein is a substrate for the peptidyl-prolyl cis/trans isomerase activity of cyclophilins A and B. PMID:19297321
Hepatitis C virus infection protein network. PMID:18985028
1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors. PMID:18852280
Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex. PMID:18799730
A genetic interaction between hepatitis C virus NS4B and NS3 is important for RNA replication. PMID:18715921
Structural and functional characterization of nonstructural protein 2 for its role in hepatitis C virus assembly. PMID:18644781
Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase. PMID:18574240
Cell culture adaptation of hepatitis C virus and in vivo viability of an adapted variant. PMID:17881454
Sequence diversity of hepatitis C virus: implications for immune control and therapy. PMID:17828811
Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions. PMID:17658949
The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specific glycans on the E2 envelope protein. PMID:17522218
New pandemics: HIV and AIDS, HCV and chronic hepatitis, influenza virus and flu. PMID:17270043
Conserved determinants for membrane association of nonstructural protein 5A from hepatitis C virus and related viruses. PMID:17192310
The euHCVdb suite of in silico tools for investigating the structural impact of mutations in hepatitis C virus proteins PubMed citations: 4.

4 articles citing: The euHCVdb suite of in silico tools for investigating the structural impact of mutations in hepatitis C virus proteins

Hepatitis C Virus Resistance to Carbohydrate-Binding Agents. PMID:26871442
Synthetic lethals in HIV: ways to avoid drug resistance : Running title: Preventing HIV resistance. PMID:25888435
Pathway and network approaches for identification of cancer signature markers from omics data. PMID:25553089
New opportunities to fight against infectious diseases and to identify pertinent drug targets with novel methodologies. PMID:19519478
http://dx.doi.org/10.1093/nar/gkl970

Tags:

Tags
More detailed information about this field from each metasource.

function analysis
metasource: Fairsharing.org
version: FAIRsharing.org: euHCVdb; European Hepatitis C Virus database; DOI: https://doi.org/10.25504/FAIRsharing.bwctv; Last edited: June 23, 2021, 10:14 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

molecular function
metasource: Fairsharing.org
version: FAIRsharing.org: euHCVdb; European Hepatitis C Virus database; DOI: https://doi.org/10.25504/FAIRsharing.bwctv; Last edited: June 23, 2021, 10:14 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

protein
metasource: Fairsharing.org
version: FAIRsharing.org: euHCVdb; European Hepatitis C Virus database; DOI: https://doi.org/10.25504/FAIRsharing.bwctv; Last edited: June 23, 2021, 10:14 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

protein structure
metasource: Fairsharing.org
version: FAIRsharing.org: euHCVdb; European Hepatitis C Virus database; DOI: https://doi.org/10.25504/FAIRsharing.bwctv; Last edited: June 23, 2021, 10:14 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

polypeptide_region
metasource: Fairsharing.org
version: FAIRsharing.org: euHCVdb; European Hepatitis C Virus database; DOI: https://doi.org/10.25504/FAIRsharing.bwctv; Last edited: June 23, 2021, 10:14 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

genomics databases (non-vertebrate)
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

viral genome databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

covid-19
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

rna
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

bioinformatics
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

drug design
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

genomics
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

genotypes
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

hepatitis
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

infection
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

molecular modelling
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

resistance
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

sequence analysis
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

virus
metasource: re3data.org
version: re3data.org: euHCVdb; editing status 2020-04-24; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3R044 last accessed: 2022-11-04

virology
metasource: bio.tools
version: extracted_at: 2022-11-04T11:36:16.291264

function analysis molecular function protein protein structure polypeptide region genomics viral genome covid-19 rna bioinformatics drug design genomics genotypes hepatitis infection molecular modelling resistance sequence analysis virus virology

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