Predicting Protein-Protein Interactions via Random Ferns with Evolutionary Matrix Representation.
PMID:35242211
Systems Biology-Derived Genetic Signatures of Mastitis in Dairy Cattle: A New Avenue for Drug Repurposing.
PMID:35011134
ConsensusPathDB 2022: molecular interactions update as a resource for network biology.
PMID:34850110
Self-Attention-Based Models for the Extraction of Molecular Interactions from Biological Texts.
PMID:34827589
Tumor relevant protein functional interactions identified using bipartite graph analyses.
PMID:34728699
Network-based protein-protein interaction prediction method maps perturbations of cancer interactome.
PMID:34727106
Investigating Pathogenetic Mechanisms of Alzheimer's Disease by Systems Biology Approaches for Drug Discovery.
PMID:34681938
Robust and accurate prediction of protein-protein interactions by exploiting evolutionary information.
PMID:34413375
Gentamicin-induced hearing loss: A retrospective study using the Food and Drug Administration Adverse Event Reporting System and a toxicological study using drug-gene network analysis.
PMID:34401547
Revealing protein-protein interactions at the transcriptome scale by sequencing.
PMID:34348091
Omics Multi-Layers Networks Provide Novel Mechanistic and Functional Insights Into Fat Storage and Lipid Metabolism in Poultry.
PMID:34306005
Geometry and symmetry in biochemical reaction systems.
PMID:34268705
Databases for Protein-Protein Interactions.
PMID:34236665
mPPI: a database extension to visualize structural interactome in a one-to-many manner.
PMID:34156447
Multiple-Molecule Drug Design Based on Systems Biology Approaches and Deep Neural Network to Mitigate Human Skin Aging.
PMID:34073305
KEA3: improved kinase enrichment analysis via data integration.
PMID:34019655
Integration of peripheral transcriptomics, genomics, and interactomics following trauma identifies causal genes for symptoms of post-traumatic stress and major depression.
PMID:33963278
Systems Medicine Design for Triple-Negative Breast Cancer and Non-Triple-Negative Breast Cancer Based on Systems Identification and Carcinogenic Mechanisms.
PMID:33802957
Genome analyses of 174 strains of Mycobacterium tuberculosis provide insight into the evolution of drug resistance and reveal potential drug targets.
PMID:33750515
Comparative analysis on the anti-inflammatory/immune effect of mesenchymal stem cell therapy for the treatment of pulmonary arterial hypertension.
PMID:33479312
Bioinformatics: new tools and applications in life science and personalized medicine.
PMID:33404829
Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications.
PMID:33375269
Chemocentric Informatics Analysis: Dexamethasone Versus Combination Therapy for COVID-19.
PMID:33251412
Implementation of homology based and non-homology based computational methods for the identification and annotation of orphan enzymes: using Mycobacterium tuberculosis H37Rv as a case study.
PMID:33076816
Integrating Single-Step GWAS and Bipartite Networks Reconstruction Provides Novel Insights into Yearling Weight and Carcass Traits in Hanwoo Beef Cattle.
PMID:33050182
Investigating Core Signaling Pathways of Hepatitis B Virus Pathogenesis for Biomarkers Identification and Drug Discovery via Systems Biology and Deep Learning Method.
PMID:32878239
Systems Biology Approaches to Understanding the Human Immune System.
PMID:32849587
Genome-wide Enrichment of De Novo Coding Mutations in Orofacial Cleft Trios.
PMID:32574564
A network analysis to identify pathophysiological pathways distinguishing ischaemic from non-ischaemic heart failure.
PMID:32243695
Systematic analysis of ovarian cancer platinum-resistance mechanisms via text mining.
PMID:32160916
Exploring Integrative Analysis Using the BioMedical Evidence Graph.
PMID:32097025
A Guide to Conquer the Biological Network Era Using Graph Theory.
PMID:32083072
Long-term survivors of early breast cancer treated with chemotherapy are characterized by a pro-inflammatory biomarker profile compared to matched controls.
PMID:32078215
Genome-wide inference of the Camponotus floridanus protein-protein interaction network using homologous mapping and interacting domain profile pairs.
PMID:32047225
NAPAbench 2: A network synthesis algorithm for generating realistic protein-protein interaction (PPI) network families.
PMID:31986158
Dissecting the Role of NF-κb Protein Family and Its Regulators in Rheumatoid Arthritis Using Weighted Gene Co-Expression Network.
PMID:31824568
Qualitative transcriptional signature for predicting pathological response of colorectal cancer to FOLFOX therapy.
PMID:31785020
Pathway Commons 2019 Update: integration, analysis and exploration of pathway data.
PMID:31647099
HMNPPID-human malignant neoplasm protein-protein interaction database.
PMID:31639057
Computational chemoproteomics to understand the role of selected psychoactives in treating mental health indications.
PMID:31511563
Differential network analysis and protein-protein interaction study reveals active protein modules in glucocorticoid resistance for infant acute lymphoblastic leukemia.
PMID:31370801
A comprehensive study on genome-wide coexpression network of KHDRBS1/Sam68 reveals its cancer and patient-specific association.
PMID:31366900
Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification.
PMID:31217907
Prediction of key regulators and downstream targets of E. coli induced mastitis.
PMID:31187384
Mining Featured Biomarkers Linked with Epithelial Ovarian CancerBased on Bioinformatics.
PMID:30970615
Disease association of human tumor suppressor genes.
PMID:30945018
Investigating Common Pathogenic Mechanisms between Homo sapiens and Different Strains of Candida albicans for Drug Design: Systems Biology Approach via Two-Sided NGS Data Identification.
PMID:30769958
Analysis of Topological Parameters of Complex Disease Genes Reveals the Importance of Location in a Biomolecular Network.
PMID:30769902
Network spectra for drug-target identification in complex diseases: new guns against old foes.
PMID:30596144
iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data.
PMID:30567491
Network Pharmacology to Unveil the Biological Basis of Health-Strengthening Herbal Medicine in Cancer Treatment.
PMID:30469422
Context-specific interactions in literature-curated protein interaction databases.
PMID:30340458
A mitochondrial proteome profile indicative of type 2 diabetes mellitus in skeletal muscles.
PMID:30266947
Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling.
PMID:30239736
Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation.
PMID:30143610
Investigating genetic-and-epigenetic networks, and the cellular mechanisms occurring in Epstein-Barr virus-infected human B lymphocytes via big data mining and genome-wide two-sided NGS data identification.
PMID:30133498
PPInS: a repository of protein-protein interaction sitesbase.
PMID:30127348
Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken.
PMID:30086717
Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery.
PMID:30082644
An unsupervised machine learning method for discovering patient clusters based on genetic signatures.
PMID:30016722
Functional analysis of gene expression profiling-based prediction in bladder cancer.
PMID:29805577
Discovering novel SNPs that are correlated with patient outcome in a Singaporean cancer patient cohort treated with gemcitabine-based chemotherapy.
PMID:29751792
Determining the minimum number of protein-protein interactions required to support known protein complexes.
PMID:29698482
JAMI: a Java library for molecular interactions and data interoperability.
PMID:29642846
Systematic Evaluation of Molecular Networks for Discovery of Disease Genes.
PMID:29605183
Key genes and regulatory networks involved in the initiation, progression and invasion of colorectal cancer.
PMID:29568567
Gastric cancer biomarkers; A systems biology approach.
PMID:29556568
Predicted Arabidopsis Interactome Resource and Gene Set Linkage Analysis: A Transcriptomic Analysis Resource.
PMID:29530937
Extracellular vesicle RNAs reflect placenta dysfunction and are a biomarker source for preterm labour.
PMID:29516617
Brain-specific functional relationship networks inform autism spectrum disorder gene prediction.
PMID:29507298
An Integrated Lipidomics and Phenotype Study Reveals Protective Effect and Biochemical Mechanism of Traditionally Used Alisma orientale Juzepzuk in Chronic Kidney Disease.
PMID:29472858
Bioinformatic analysis of gene expression profiling of intracranial aneurysm.
PMID:29328431
Feature genes in metastatic breast cancer identified by MetaDE and SVM classifier methods.
PMID:29328377
Systematic target function annotation of human transcription factors.
PMID:29325558
The node-weighted Steiner tree approach to identify elements of cancer-related signaling pathways.
PMID:29297291
The integration of weighted gene association networks based on information entropy.
PMID:29272314
Dynamic covalent chemistry enables formation of antimicrobial peptide quaternary assemblies in a completely abiotic manner.
PMID:29256509
MiRIAD update: using alternative polyadenylation, protein interaction network analysis and additional species to enhance exploration of the role of intragenic miRNAs and their host genes.
PMID:29220447
Repository corticotrophin injection exerts direct acute effects on human B cell gene expression distinct from the actions of glucocorticoids.
PMID:29205315
Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches.
PMID:29186305
The UCSC Genome Browser database: 2018 update.
PMID:29106570
Multi-dimensional histone methylations for coordinated regulation of gene expression under hypoxia.
PMID:28977425
Protein-Protein Interactions in Virus-Host Systems.
PMID:28861068
ePlant: Visualizing and Exploring Multiple Levels of Data for Hypothesis Generation in Plant Biology.
PMID:28808136
Genetic and functional characterization of disease associations explains comorbidity.
PMID:28740175
Identification of pivotal genes and pathways for spinal cord injury via bioinformatics analysis.
PMID:28731189
Special role of JUN in papillary thyroid carcinoma based on bioinformatics analysis.
PMID:28673327
HGPEC: a Cytoscape app for prediction of novel disease-gene and disease-disease associations and evidence collection based on a random walk on heterogeneous network.
PMID:28619054
Determining Complex Structures using Docking Method with Single Particle Scattering Data.
PMID:28487857
Accurate prediction of protein-protein interactions by integrating potential evolutionary information embedded in PSSM profile and discriminative vector machine classifier.
PMID:28423569
Study of intra-inter species protein-protein interactions for potential drug targets identification and subsequent drug design for Escherichia coli O104:H4 C277-11.
PMID:28401513
Deficiency in Sperm-Egg Protein Interaction as a Major Cause of Fertilization Failure.
PMID:28280854
A Comprehensive Gene Expression Meta-analysis Identifies Novel Immune Signatures in Rheumatoid Arthritis Patients.
PMID:28210261
TrypsNetDB: An integrated framework for the functional characterization of trypanosomatid proteins.
PMID:28158179
Binding of small molecules at interface of protein-protein complex - A newer approach to rational drug design.
PMID:28149177
Computational methods in drug discovery.
PMID:28144341
The integration of weighted human gene association networks based on link prediction.
PMID:28137253
Systematic analysis of molecular mechanisms for HCC metastasis via text mining approach.
PMID:28108733
Automatic query generation using word embeddings for retrieving passages describing experimental methods.
PMID:28077568
Improving protein complex prediction by reconstructing a high-confidence protein-protein interaction network of Escherichia coli from different physical interaction data sources.
PMID:28049415
Genomic expression differences between cutaneous cells from red hair color individuals and black hair color individuals based on bioinformatic analysis.
PMID:28030792
A scored human protein-protein interaction network to catalyze genomic interpretation.
PMID:27892958
Prediction of interacting proteins from homology-modeled complex structures using sequence and structure scores.
PMID:27857563
HINT: a database of annotated protein-protein interactions and their homologs.
PMID:27857549
Integrating network, sequence and functional features using machine learning approaches towards identification of novel Alzheimer genes.
PMID:27756223
Exploring the interactions of the RAS family in the human protein network and their potential implications in RAS-directed therapies.
PMID:27713118
Celecoxib exhibits an anti-gastric cancer effect by targeting focal adhesion and leukocyte transendothelial migration-associated genes.
PMID:27698798
Comprehensive Proteome Profiling of Platelet Identified a Protein Profile Predictive of Responses to An Antiplatelet Agent Sarpogrelate.
PMID:27601597
A Shortest Dependency Path Based Convolutional Neural Network for Protein-Protein Relation Extraction.
PMID:27493967
Small-molecule binding sites to explore protein-protein interactions in the cancer proteome.
PMID:27452673
Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling Networks.
PMID:27403431
HPIDB 2.0: a curated database for host-pathogen interactions.
PMID:27374121
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins.
PMID:27374120
A new strategy for exploring the hierarchical structure of cancers by adaptively partitioning functional modules from gene expression network.
PMID:27349736
FOXR2 Interacts with MYC to Promote Its Transcriptional Activities and Tumorigenesis.
PMID:27346356
BioTriangle: a web-accessible platform for generating various molecular representations for chemicals, proteins, DNAs/RNAs and their interactions.
PMID:27330567
Data-based Reconstruction of Gene Regulatory Networks of Fungal Pathogens.
PMID:27148247
Sequence-based prediction of protein-protein interactions using weighted sparse representation model combined with global encoding.
PMID:27112932
Network-Based Protein Biomarker Discovery Platforms.
PMID:27103885
Exploring Polypharmacology in Drug Discovery and Repurposing Using the CANDO Platform.
PMID:27013226
Proteomics-Based Analysis of Protein Complexes in Pluripotent Stem Cells and Cancer Biology.
PMID:27011181
Comparative Proteomic Analysis of Advanced Ovarian Cancer Tissue to Identify Potential Biomarkers of Responders and Nonresponders to First-Line Chemotherapy of Carboplatin and Paclitaxel.
PMID:26997873
PIPINO: A Software Package to Facilitate the Identification of Protein-Protein Interactions from Affinity Purification Mass Spectrometry Data.
PMID:26966684
Tyrosine Phosphorylation Based Homo-dimerization of Arabidopsis RACK1A Proteins Regulates Oxidative Stress Signaling Pathways in Yeast.
PMID:26941753
Key Immune Events of the Pathomechanisms of Early Cardioembolic Stroke: Multi-Database Mining and Systems Biology Approach.
PMID:26927091
An interactive web-based application for Comprehensive Analysis of RNAi-screen Data.
PMID:26902267
Comparative analysis of housekeeping and tissue-selective genes in human based on network topologies and biological properties.
PMID:26897376
Rsite2: an efficient computational method to predict the functional sites of noncoding RNAs.
PMID:26751501
Fundamentals of protein interaction network mapping.
PMID:26681426
Using Weighted Sparse Representation Model Combined with Discrete Cosine Transformation to Predict Protein-Protein Interactions from Protein Sequence.
PMID:26634213
Transcriptator: An Automated Computational Pipeline to Annotate Assembled Reads and Identify Non Coding RNA.
PMID:26581084
Identification of key genes associated with the human abdominal aortic aneurysm based on the gene expression profile.
PMID:26498477
Discovering distinct functional modules of specific cancer types using protein-protein interaction networks.
PMID:26495282
Interlog protein network: an evolutionary benchmark of protein interaction networks for the evaluation of clustering algorithms.
PMID:26437714
Integrative analysis of human protein, function and disease networks.
PMID:26399914
Meta-Analysis of Large-Scale Toxicogenomic Data Finds Neuronal Regeneration Related Protein and Cathepsin D to Be Novel Biomarkers of Drug-Induced Toxicity.
PMID:26335687
A computational framework for the prioritization of disease-gene candidates.
PMID:26330267
Network Modules of the Cross-Species Genotype-Phenotype Map Reflect the Clinical Severity of Human Diseases.
PMID:26301634
Bioinformatics analysis to identify the differentially expressed genes of glaucoma.
PMID:26135629
Surfing the Protein-Protein Interaction Surface Using Docking Methods: Application to the Design of PPI Inhibitors.
PMID:26111183
Proteins interaction network and modeling of IGVH mutational status in chronic lymphocytic leukemia.
PMID:26088082
Dynamic network-based relevance score reveals essential proteins and functional modules in directed differentiation.
PMID:25977693
A novel method for identifying disease associated protein complexes based on functional similarity protein complex networks.
PMID:25969691
NetworkAnalyst for statistical, visual and network-based meta-analysis of gene expression data.
PMID:25950236
Identifying module biomarker in type 2 diabetes mellitus by discriminative area of functional activity.
PMID:25888350
Inbreeding Affects Gene Expression Differently in Two Self-Incompatible Arabidopsis lyrata Populations with Similar Levels of Inbreeding Depression.
PMID:25855783
Comprehensive data resources and analytical tools for pathological association of aminoacyl tRNA synthetases with cancer.
PMID:25824651
Expression profile of mitrogen-activated protein kinase (MAPK) signaling genes in the skeletal muscle & liver of rat with type 2 diabetes: role in disease pathology.
PMID:25758573
An integrative approach for a network based meta-analysis of viral RNAi screens.
PMID:25691914
Network representations of immune system complexity.
PMID:25625853
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
PMID:25609649
Pathway mapping and development of disease-specific biomarkers: protein-based network biomarkers.
PMID:25560835
MicroRNA Dysregulation, Gene Networks, and Risk for Schizophrenia in 22q11.2 Deletion Syndrome.
PMID:25484875
A proteome-scale map of the human interactome network.
PMID:25416956
Protein interaction networks reveal novel autism risk genes within GWAS statistical noise.
PMID:25409314
A systems biology strategy to identify molecular mechanisms of action and protein indicators of traumatic brain injury.
PMID:25399920
Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions.
PMID:25392414
Integrated analysis of microarray data of atherosclerotic plaques: modulation of the ubiquitin-proteasome system.
PMID:25333956
GroupRank: rank candidate genes in PPI network by differentially expressed gene groups.
PMID:25330105
Hope for GWAS: relevant risk genes uncovered from GWAS statistical noise.
PMID:25268625
Prioritisation and network analysis of Crohn's disease susceptibility genes.
PMID:25268122
Computational analysis of signaling patterns in single cells.
PMID:25263011
A random set scoring model for prioritization of disease candidate genes using protein complexes and data-mining of GeneRIF, OMIM and PubMed records.
PMID:25253562
Activation of diverse signalling pathways by oncogenic PIK3CA mutations.
PMID:25247763
Gene expression profiles on predicting protein interaction network and exploring of new treatments for lung cancer.
PMID:25205123
Construction and analysis of the protein-protein interaction networks based on gene expression profiles of Parkinson's disease.
PMID:25170921
Functional and genomic context in pathway analysis of GWAS data.
PMID:25154796
A bayesian framework that integrates heterogeneous data for inferring gene regulatory networks.
PMID:25152886
From pathways to networks: connecting dots by establishing protein-protein interaction networks in signaling pathways using affinity purification and mass spectrometry.
PMID:25137225
BioBenchmark Toyama 2012: an evaluation of the performance of triple stores on biological data.
PMID:25089180
Text-mining-assisted biocuration workflows in Argo.
PMID:25037308
An unsupervised text mining method for relation extraction from biomedical literature.
PMID:25036529
Predicting disease-related proteins based on clique backbone in protein-protein interaction network.
PMID:25013377
Systems biology in the context of big data and networks.
PMID:24982882
Pathway reconstruction of airway remodeling in chronic lung diseases: a systems biology approach.
PMID:24978043
Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte.
PMID:24949636
New directions for diffusion-based network prediction of protein function: incorporating pathways with confidence.
PMID:24931987
Phosphokinase antibody arrays on dendron-coated surface.
PMID:24802362
Impact of vitamin D on immune function: lessons learned from genome-wide analysis.
PMID:24795646
Modelling the yeast interactome.
PMID:24589662
PARK2 and proinflammatory/anti-inflammatory cytokine gene interactions contribute to the susceptibility to leprosy: a case-control study of North Indian population.
PMID:24578538
Corbi: a new R package for biological network alignment and querying.
PMID:24565104
RRHGE: a novel approach to classify the estrogen receptor based breast cancer subtypes.
PMID:24563630
Review of biological network data and its applications.
PMID:24465231
Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.
PMID:24413017
A protein profile of visceral adipose tissues linked to early pathogenesis of type 2 diabetes mellitus.
PMID:24403596
Computational Prediction of Protein-Protein Interaction Networks: Algo-rithms and Resources.
PMID:24396273
WikiPathways for plants: a community pathway curation portal and a case study in rice and arabidopsis seed development networks.
PMID:24280312
Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer.
PMID:24278371
Drug repositioning by kernel-based integration of molecular structure, molecular activity, and phenotype data.
PMID:24244318
Gentrepid V2.0: a web server for candidate disease gene prediction.
PMID:23947436
Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis.
PMID:23922650
JBioWH: an open-source Java framework for bioinformatics data integration.
PMID:23846595
Module-based breast cancer classification.
PMID:23819260
A nutrigenomic framework to identify time-resolving responses of hepatic genes in diet-induced obese mice.
PMID:23813319
Cataloging the biomedical world of pain through semi-automated curation of molecular interactions.
PMID:23707966
An efficient weighted graph strategy to identify differentiation associated genes in embryonic stem cells.
PMID:23638139
An integrated approach to uncover driver genes in breast cancer methylation genomes.
PMID:23579546
Gene expression analysis distinguishes tissue-specific and gender-related functions among adult Ascaris suum tissues.
PMID:23572074
t-LSE: a novel robust geometric approach for modeling protein-protein interaction networks.
PMID:23560036
The potential of text mining in data integration and network biology for plant research: a case study on Arabidopsis.
PMID:23532071
Vitexicarpin acts as a novel angiogenesis inhibitor and its target network.
PMID:23476684
Predicting the binding patterns of hub proteins: a study using yeast protein interaction networks.
PMID:23431393
Equal opportunity for low-degree network nodes: a PageRank-based method for protein target identification in metabolic graphs.
PMID:23382878
Predicting PDZ domain mediated protein interactions from structure.
PMID:23336252
Chapter 2: Data-driven view of disease biology.
PMID:23300408
Identification of MFS proteins in sorghum using semantic similarity.
PMID:23299296
PCDq: human protein complex database with quality index which summarizes different levels of evidences of protein complexes predicted from h-invitational protein-protein interactions integrative dataset.
PMID:23282181
Kaposi's sarcoma: a computational approach through protein-protein interaction and gene regulatory networks analysis.
PMID:23266878
Investigation of stable and transient protein-protein interactions: Past, present, and future.
PMID:23193082
Interactogeneous: disease gene prioritization using heterogeneous networks and full topology scores.
PMID:23185389
Systems analysis of plant functional, transcriptional, physical interaction, and metabolic networks.
PMID:23110892
Combing the hairball with BioFabric: a new approach for visualization of large networks.
PMID:23102059
Popular computational methods to assess multiprotein complexes derived from label-free affinity purification and mass spectrometry (AP-MS) experiments.
PMID:23071097
Dr. PIAS 2.0: an update of a database of predicted druggable protein-protein interactions.
PMID:23060433
What evidence is there for the homology of protein-protein interactions?
PMID:23028270
SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.
PMID:22974441
Biological function through network topology: a survey of the human diseasome.
PMID:22962330
Sets2Networks: network inference from repeated observations of sets.
PMID:22824380
The co-regulation mechanism of transcription factors in the human gene regulatory network.
PMID:22798495
Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models.
PMID:22737156
Proteome-wide prediction of protein-protein interactions from high-throughput data.
PMID:22729399
Network compression as a quality measure for protein interaction networks.
PMID:22719828
BIPS: BIANA Interolog Prediction Server. A tool for protein-protein interaction inference.
PMID:22689642
Inferring high-confidence human protein-protein interactions.
PMID:22558947
Network- and attribute-based classifiers can prioritize genes and pathways for autism spectrum disorders and intellectual disability.
PMID:22499558
Integrated inference and analysis of regulatory networks from multi-level measurements.
PMID:22482944
Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses.
PMID:22458338
HIPPIE: Integrating protein interaction networks with experiment based quality scores.
PMID:22348130
ANAP: an integrated knowledge base for Arabidopsis protein interaction network analysis.
PMID:22345505
Fast and accurate modeling of protein-protein interactions by combining template-interface-based docking with flexible refinement.
PMID:22275112
A searchable cross-platform gene expression database reveals connections between drug treatments and disease.
PMID:22233519
Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.
PMID:22219718
Classifying protein-protein interaction articles using word and syntactic features.
PMID:22151252
Defining the role of essential genes in human disease.
PMID:22096564
Chronic morphine alters the presynaptic protein profile: identification of novel molecular targets using proteomics and network analysis.
PMID:22043286
Proteomic analysis of Col11a1-associated protein complexes.
PMID:22038862
An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine.
PMID:22022502
Systems-biology approaches to discover anti-viral effectors of the human innate immune response.
PMID:21994773
Abnormal expression of FLI1 protein is an adverse prognostic factor in acute myeloid leukemia.
PMID:21917756
A physical interaction network of dengue virus and human proteins.
PMID:21911577
Insight into bacterial virulence mechanisms against host immune response via the Yersinia pestis-human protein-protein interaction network.
PMID:21911467
Predicting protein-protein interactions on a proteome scale by matching evolutionary and structural similarities at interfaces using PRISM.
PMID:21886100
Application of computational systems biology to explore environmental toxicity hazards.
PMID:21846611
NETGEM: Network Embedded Temporal GEnerative Model for gene expression data.
PMID:21824426
Enhancers regulate progression of development in mammalian cells.
PMID:21785139
Proteomic patterns of cervical cancer cell lines, a network perspective.
PMID:21696634
Integrative computational biology for cancer research.
PMID:21691773
LinkinPath: from sequence to interconnected pathway.
PMID:21636594
Constructing de novo biosynthetic pathways for chemical synthesis inside living cells.
PMID:21591680
Assessing the biological significance of gene expression signatures and co-expression modules by studying their network properties.
PMID:21408226
GeneRanker: An Online System for Predicting Gene-Disease Associations for Translational Research.
PMID:21347122
Comparative analysis of protein interaction networks reveals that conserved pathways are susceptible to HIV-1 interception.
PMID:21342548
ePlant and the 3D data display initiative: integrative systems biology on the world wide web.
PMID:21249219
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.
PMID:21249183
The Biomolecular Interaction Network Database in PSI-MI 2.5.
PMID:21233089
A knowledge-based weighting framework to boost the power of genome-wide association studies.
PMID:21217833
The role of exon shuffling in shaping protein-protein interaction networks.
PMID:21210967
Combining modularity, conservation, and interactions of proteins significantly increases precision and coverage of protein function prediction.
PMID:21171995
Defining the antigen receptor-dependent regulatory network that induces arrest of cycling immature B-lymphocytes.
PMID:21143896
GOAPhAR: An Integrative Discovery Tool for Annotation, Pathway Analysis.
PMID:21132056
Integrating diverse biological and computational sources for reliable protein-protein interactions.
PMID:21106130
Multi-level reproducibility of signature hubs in human interactome for breast cancer metastasis.
PMID:21059271
Global protein interactome exploration through mining genome-scale data in Arabidopsis thaliana.
PMID:21047383
Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein.
PMID:21044957
Integrative systems biology for data-driven knowledge discovery.
PMID:21044756
HitPredict: a database of quality assessed protein-protein interactions in nine species.
PMID:20947562
ChemProt: a disease chemical biology database.
PMID:20935044
MetNetGE: interactive views of biological networks and ontologies.
PMID:20849585
The BioPAX community standard for pathway data sharing.
PMID:20829833
A yeast's eye view of mammalian reproduction: cross-species gene co-expression in meiotic prophase.
PMID:20819218
The STINT-NMR method for studying in-cell protein-protein interactions.
PMID:20814930
Measuring the physical cohesiveness of proteins using physical interaction enrichment.
PMID:20798171
Development of a novel bioinformatics tool for in silico validation of protein interactions.
PMID:20625507
Literature-based discovery of IFN-gamma and vaccine-mediated gene interaction networks.
PMID:20625487
A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.
PMID:20531406
Exploratory analysis of protein translation regulatory networks using hierarchical random graphs.
PMID:20438649
Improved microarray-based decision support with graph encoded interactome data.
PMID:20419106
Predicting protein-protein interactions in unbalanced data using the primary structure of proteins.
PMID:20361868
Construction and analysis of protein-protein interaction networks.
PMID:20334628
Bioinformatic tools for identifying disease gene and SNP candidates.
PMID:20238089
Pathway Palette: a rich internet application for peptide-, protein- and network-oriented analysis of MS data.
PMID:20198642
Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase.
PMID:20194642
High-throughput discovery and characterization of fetal protein trafficking in the blood of pregnant women.
PMID:20186258
Walk-weighted subsequence kernels for protein-protein interaction extraction.
PMID:20184736
Xenopus meiotic microtubule-associated interactome.
PMID:20174651
Lists2Networks: integrated analysis of gene/protein lists.
PMID:20152038
Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning.
PMID:20134029
Gene prioritization in Type 2 Diabetes using domain interactions and network analysis.
PMID:20122255
An ontology-based search engine for protein-protein interactions.
PMID:20122195
Comparative evolutionary analysis of protein complexes in E. coli and yeast.
PMID:20122144
Automatic inference of multicellular regulatory networks using informative priors.
PMID:20090166
CORNET: a user-friendly tool for data mining and integration.
PMID:20053712
VirtualPlant: a software platform to support systems biology research.
PMID:20007449
Expression-based network biology identifies alteration in key regulatory pathways of type 2 diabetes and associated risk/complications.
PMID:19997558
Network-based Identification of novel cancer genes.
PMID:19959820
CORUM: the comprehensive resource of mammalian protein complexes--2009.
PMID:19884131
NAViGaTOR: Network Analysis, Visualization and Graphing Toronto.
PMID:19837718
Integrating diverse information to gain more insight into microarray analysis.
PMID:19834567
Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation.
PMID:19828076
VANLO--interactive visual exploration of aligned biological networks.
PMID:19821976
PathBinder--text empirics and automatic extraction of biomolecular interactions.
PMID:19811683
Prediction of candidate primary immunodeficiency disease genes using a support vector machine learning approach.
PMID:19801557
Detection of molecular paths associated with insulitis and type 1 diabetes in non-obese diabetic mouse.
PMID:19798418
Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network.
PMID:19728866
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair.
PMID:19684605
CAPIH: a Web interface for comparative analyses and visualization of host-HIV protein-protein interactions.
PMID:19674441
Scaffolds: interaction platforms for cellular signalling circuits.
PMID:19651513
Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts.
PMID:19649302
BioNetBuilder2.0: bringing systems biology to chicken and other model organisms.
PMID:19607657
Towards inferring time dimensionality in protein-protein interaction networks by integrating structures: the p53 example.
PMID:19585003
Candidate List of yoUr Biomarker (CLUB): A Web-based Platform to Aid Cancer Biomarker Research.
PMID:19578495
PIAS proteins: pleiotropic interactors associated with SUMO.
PMID:19526197
DASMIweb: online integration, analysis and assessment of distributed protein interaction data.
PMID:19502495
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization.
PMID:19465376
SNOW, a web-based tool for the statistical analysis of protein-protein interaction networks.
PMID:19454602
Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships.
PMID:19426461
DASMI: exchanging, annotating and assessing molecular interaction data.
PMID:19420069
Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins.
PMID:19402753
Rich can get poor: conversion of hub to non-hub proteins.
PMID:19399641
Perturbation of interaction networks for application to cancer therapy.
PMID:19390668
POINeT: protein interactome with sub-network analysis and hub prioritization.
PMID:19379523
FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions.
PMID:19374773
Identifying disease-specific genes based on their topological significance in protein networks.
PMID:19309513
Global networks of functional coupling in eukaryotes from comprehensive data integration.
PMID:19246318
Disease candidate gene identification and prioritization using protein interaction networks.
PMID:19245720
A survey of available tools and web servers for analysis of protein-protein interactions and interfaces.
PMID:19240123
Enumeration of condition-dependent dense modules in protein interaction networks.
PMID:19213739
Dissecting the interface between signaling and transcriptional regulation in human B cells.
PMID:19209707
Literature-curated protein interaction datasets.
PMID:19116613
Meta-analysis of expression signatures of muscle atrophy: gene interaction networks in early and late stages.
PMID:19108710
POLAR MAPPER: a computational tool for integrated visualization of protein interaction networks and mRNA expression data.
PMID:19091689
An experimentally derived confidence score for binary protein-protein interactions.
PMID:19060903
Computational and experimental approaches to chart the Escherichia coli cell-envelope-associated proteome and interactome.
PMID:19054114
Hepatitis C virus infection protein network.
PMID:18985028
Michigan molecular interactions r2: from interacting proteins to pathways.
PMID:18978014
Physical protein-protein interactions predicted from microarrays.
PMID:18829707
iRefIndex: a consolidated protein interaction database with provenance.
PMID:18823568
ProteoLens: a visual analytic tool for multi-scale database-driven biological network data mining.
PMID:18793469
OKCAM: an ontology-based, human-centered knowledgebase for cell adhesion molecules.
PMID:18790807
RNA interference screen for human genes associated with West Nile virus infection.
PMID:18690214
Integrating protein-protein interactions and text mining for protein function prediction.
PMID:18673526
Using multiple ontologies to integrate complex biological data.
PMID:18629202
The molecule role ontology: an ontology for annotation of signal transduction pathway molecules in the scientific literature.
PMID:18629146
TRANSPATH--a high quality database focused on signal transduction.
PMID:18629064
Interactome data and databases: different types of protein interaction.
PMID:18629062
Construction of a cancer-perturbed protein-protein interaction network for discovery of apoptosis drug targets.
PMID:18590547
Identifying gene-disease associations using centrality on a literature mined gene-interaction network.
PMID:18586725
Hubba: hub objects analyzer--a framework of interactome hubs identification for network biology.
PMID:18503085
Design logic of a cannabinoid receptor signaling network that triggers neurite outgrowth.
PMID:18487186
Network-based global inference of human disease genes.
PMID:18463613
VisANT: an integrative framework for networks in systems biology.
PMID:18463131
Steps towards a repertoire of comprehensive maps of human protein interaction networks: the Human Proteotheque Initiative (HuPI).
PMID:18443628
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data.
PMID:18426580
A map of human protein interactions derived from co-expression of human mRNAs and their orthologs.
PMID:18414481
Protein networks in disease.
PMID:18381899
Exploiting likely-positive and unlabeled data to improve the identification of protein-protein interaction articles.
PMID:18315856
DBMLoc: a Database of proteins with multiple subcellular localizations.
PMID:18304364
SPIKE--a database, visualization and analysis tool of cellular signaling pathways.
PMID:18289391
Linking the ovarian cancer transcriptome and immunome.
PMID:18173842
PepCyber:P~PEP: a database of human protein protein interactions mediated by phosphoprotein-binding domains.
PMID:18160410
Computational prediction of protein-protein interactions.
PMID:18095187
PARPs database: a LIMS systems for protein-protein interaction data mining or laboratory information management system.
PMID:18093328
EndoNet: an information resource about regulatory networks of cell-to-cell communication.
PMID:18045786
Integrative analysis for finding genes and networks involved in diabetes and other complex diseases.
PMID:18045462
Hubs with network motifs organize modularity dynamically in the protein-protein interaction network of yeast.
PMID:18030341
DIMA 2.0--predicted and known domain interactions.
PMID:17999995
Host pathogen protein interactions predicted by comparative modeling.
PMID:17965183
The Molecule Pages database.
PMID:17965093
CORUM: the comprehensive resource of mammalian protein complexes.
PMID:17965090
AtPID: Arabidopsis thaliana protein interactome database--an integrative platform for plant systems biology.
PMID:17962307
Improved human disease candidate gene prioritization using mouse phenotype.
PMID:17939863
Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases.
PMID:17916244
Statistical analysis of physical-chemical properties and prediction of protein-protein interfaces.
PMID:17828612
The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists.
PMID:17784955
A data integration approach for cell cycle analysis oriented to model simulation in systems biology.
PMID:17678529
A predicted interactome for Arabidopsis.
PMID:17675552
Functional atlas of the integrin adhesome.
PMID:17671451
PHIDIAS: a pathogen-host interaction data integration and analysis system.
PMID:17663773
Automating document classification for the Immune Epitope Database.
PMID:17655769
Characterization of protein-interaction networks in tumors.
PMID:17597514
Web services at the European bioinformatics institute.
PMID:17576686
In search of the biological significance of modular structures in protein networks.
PMID:17542644
Advancing translational research with the Semantic Web.
PMID:17493285
Reconstruction of human protein interolog network using evolutionary conserved network.
PMID:17493278
FatiGO +: a functional profiling tool for genomic data. Integration of functional annotation, regulatory motifs and interaction data with microarray experiments.
PMID:17478504
The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics.
PMID:17447836
Epstein-Barr virus and virus human protein interaction maps.
PMID:17446270
In silico pathway reconstruction: Iron-sulfur cluster biogenesis in Saccharomyces cerevisiae.
PMID:17408500
Reactome: a knowledge base of biologic pathways and processes.
PMID:17367534
From bytes to bedside: data integration and computational biology for translational cancer research.
PMID:17319736
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology.
PMID:17254302
RINGdb: an integrated database for G protein-coupled receptors and regulators of G protein signaling.
PMID:17173697
CellCircuits: a database of protein network models.
PMID:17135207
Michigan Molecular Interactions (MiMI): putting the jigsaw puzzle together.
PMID:17130145
Analysis of protein sequence and interaction data for candidate disease gene prediction.
PMID:17020920
Genomic analysis of the hierarchical structure of regulatory networks.
PMID:17003135
Characterization and prediction of protein-protein interactions within and between complexes.
PMID:17003128
Stratus not altocumulus: a new view of the yeast protein interaction network.
PMID:16984220
Modelling protein-protein interaction networks via a stickiness index.
PMID:16971339
Cataloging the relationships between proteins: a review of interaction databases.
PMID:16943573
Design principles of molecular networks revealed by global comparisons and composite motifs.
PMID:16859507
Taverna: a tool for building and running workflows of services.
PMID:16845108
VIRGO: computational prediction of gene functions.
PMID:16845022
The cognitive phenotype of Down syndrome: insights from intracellular network analysis.
PMID:16815222
The interaction map of yeast: terra incognita?
PMID:16762048
Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae.
PMID:16762047
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks.
PMID:16749936
Protein complex compositions predicted by structural similarity.
PMID:16738133
Development of quantitative structure-binding affinity relationship models based on novel geometrical chemical descriptors of the protein-ligand interfaces.
PMID:16640331
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes.
PMID:16630345
A computational framework for the topological analysis and targeted disruption of signal transduction networks.
PMID:16617070
A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila.
PMID:16603075
SNPs3D: candidate gene and SNP selection for association studies.
PMID:16551372
NovelFam3000--uncharacterized human protein domains conserved across model organisms.
PMID:16533400
Protein protein interactions, evolutionary rate, abundance and age.
PMID:16533385
SCOWLP: a web-based database for detailed characterization and visualization of protein interfaces.
PMID:16512892
PhosphoregDB: the tissue and sub-cellular distribution of mammalian protein kinases and phosphatases.
PMID:16504016
In search of functional association from time-series microarray data based on the change trend and level of gene expression.
PMID:16478547
Computational analysis and prediction of the binding motif and protein interacting partners of the Abl SH3 domain.
PMID:16446784
EndoNet: an information resource about endocrine networks.
PMID:16381928
MPact: the MIPS protein interaction resource on yeast.
PMID:16381906
MIPS: analysis and annotation of proteins from whole genomes in 2005.
PMID:16381839
NPInter: the noncoding RNAs and protein related biomacromolecules interaction database.
PMID:16381834
MachineProse: an ontological framework for scientific assertions.
PMID:16357355
Ulysses - an application for the projection of molecular interactions across species.
PMID:16356269
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms.
PMID:16351748
Coupling actin dynamics to the endocytic process in Saccharomyces cerevisiae.
PMID:16231104
L2L: a simple tool for discovering the hidden significance in microarray expression data.
PMID:16168088
Tools enabling the elucidation of molecular pathways active in human disease: application to Hepatitis C virus infection.
PMID:15967031
The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta.
PMID:15951851
Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome.
PMID:15892868
Detecting remotely related proteins by their interactions and sequence similarity.
PMID:15883372
Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals.
PMID:15882449
The use of edge-betweenness clustering to investigate biological function in protein interaction networks.
PMID:15740614
Atlas - a data warehouse for integrative bioinformatics.
PMID:15723693
Oracle Database 10g: a platform for BLAST search and Regular Expression pattern matching in life sciences.
PMID:15608287
The Rat Genome Database (RGD): developments towards a phenome database.
PMID:15608243
The European Bioinformatics Institute's data resources: towards systems biology.
PMID:15608238
STRING: known and predicted protein-protein associations, integrated and transferred across organisms.
PMID:15608232
Reactome: a knowledgebase of biological pathways.
PMID:15608231
GeneNet in 2005.
PMID:15608230
The Biomolecular Interaction Network Database and related tools 2005 update.
PMID:15608229
Content-rich biological network constructed by mining PubMed abstracts.
PMID:15473905
System-based proteomic analysis of the interferon response in human liver cells.
PMID:15287976
InterWeaver: interaction reports for discovering potential protein interaction partners with online evidence.
PMID:15215354
Structure-function evolution of the transforming acidic coiled coil genes revealed by analysis of phylogenetically diverse organisms.
PMID:15207008
Computational approaches to protein-protein interaction.
PMID:15185965
Annotation transfer between genomes: protein-protein interologs and protein-DNA regulogs.
PMID:15173116
Predicting protein complex membership using probabilistic network reliability.
PMID:15140827
Charting gene regulatory networks: strategies, challenges and perspectives.
PMID:15080794
VisANT: an online visualization and analysis tool for biological interaction data.
PMID:15028117
Whole-genome annotation by using evidence integration in functional-linkage networks.
PMID:14981259
TopNet: a tool for comparing biological sub-networks, correlating protein properties with topological statistics.
PMID:14724320
IntAct: an open source molecular interaction database.
PMID:14681455
The Database of Interacting Proteins: 2004 update.
PMID:14681454
The aMAZE LightBench: a web interface to a relational database of cellular processes.
PMID:14681453
Visualization and interpretation of protein networks in Mycobacterium tuberculosis based on hierarchical clustering of genome-wide functional linkage maps.
PMID:14654685
The interrelationship between DRIM gene expression and cytogenetic and phenotypic characteristics in human breast tumor cell lines.
PMID:14503924
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs.
PMID:12824383
ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins.
PMID:12824381