Deciphering signal transduction networks in the liver by mechanistic mathematical modelling.
PMID:35748700
Tryptophan Production Maximization in a Fed-Batch Bioreactor with Modified E. coli Cells, by Optimizing Its Operating Policy Based on an Extended Structured Cell Kinetic Model.
PMID:34940363
A protocol for dynamic model calibration.
PMID:34619769
Synthetic Biology in Plants, a Boon for Coming Decades.
PMID:34420149
Relating simulation studies by provenance-Developing a family of Wnt signaling models.
PMID:34351901
Benchmarking of numerical integration methods for ODE models of biological systems.
PMID:33514831
KiMoSys 2.0: an upgraded database for submitting, storing and accessing experimental data for kinetic modeling.
PMID:33247931
Executable biochemical space for specification and analysis of biochemical systems.
PMID:32915842
Best Practices for Making Reproducible Biochemical Models.
PMID:32853539
Publishing reproducible dynamic kinetic models.
PMID:32793969
libsbmljs-Enabling web-based SBML tools.
PMID:32339626
A combined experimental and modelling approach for the Weimberg pathway optimisation.
PMID:32107375
Data Management in Computational Systems Biology: Exploring Standards, Tools, Databases, and Packaging Best Practices.
PMID:31602618
Closing the gap between formats for storing layout information in systems biology.
PMID:31273380
Open Source Brain: A Collaborative Resource for Visualizing, Analyzing, Simulating, and Developing Standardized Models of Neurons and Circuits.
PMID:31201122
Delving deeper: Relating the behaviour of a metabolic system to the properties of its components using symbolic metabolic control analysis.
PMID:30485345
Harmonizing semantic annotations for computational models in biology.
PMID:30462164
"Reproducible" Research in Mathematical Sciences Requires Changes in our Peer Review Culture and Modernization of our Current Publication Approach.
PMID:30232583
Identifying frequent patterns in biochemical reaction networks: a workflow.
PMID:29992320
Tellurium notebooks-An environment for reproducible dynamical modeling in systems biology.
PMID:29906293
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux.
PMID:29615663
MAGPIE: Simplifying access and execution of computational models in the life sciences.
PMID:29244826
PharmML in Action: an Interoperable Language for Modeling and Simulation.
PMID:28575551
SED-ML web tools: generate, modify and export standard-compliant simulation studies.
PMID:28049131
FAIRDOMHub: a repository and collaboration environment for sharing systems biology research.
PMID:27899646
COMODI: an ontology to characterise differences in versions of computational models in biology.
PMID:27401413
Development of an accurate kinetic model for the central carbon metabolism of Escherichia coli.
PMID:27329289
PASMet: a web-based platform for prediction, modelling and analyses of metabolic systems.
PMID:27174940
The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable.
PMID:27051515
Reproducibility in Computational Neuroscience Models and Simulations.
PMID:27046845
Challenges in horizontal model integration.
PMID:26968798
Flux Control in Glycolysis Varies Across the Tree of Life.
PMID:26920685
The Development of Computational Biology in South Africa: Successes Achieved and Lessons Learnt.
PMID:26845152
Predictive Modeling of Drug Treatment in the Area of Personalized Medicine.
PMID:26692759
Tracing regulatory routes in metabolism using generalised supply-demand analysis.
PMID:26635009
BioModels: Content, Features, Functionality, and Use.
PMID:26225232
SEEK: a systems biology data and model management platform.
PMID:26160520
Annotation-based feature extraction from sets of SBML models.
PMID:25904997
Combining computational models, semantic annotations and simulation experiments in a graph database.
PMID:25754863
Analytical study of robustness of a negative feedback oscillator by multiparameter sensitivity.
PMID:25605374
Improving collaboration by standardization efforts in systems biology.
PMID:25538939
Computational strategies for a system-level understanding of metabolism.
PMID:25427076
BioModels: ten-year anniversary.
PMID:25414348
MOSBIE: a tool for comparison and analysis of rule-based biochemical models.
PMID:25253680
KiMoSys: a web-based repository of experimental data for KInetic MOdels of biological SYStems.
PMID:25115331
What mRNA Abundances Can Tell us about Metabolism.
PMID:24957650
Optimality principles in the regulation of metabolic networks.
PMID:24957646
SensA: web-based sensitivity analysis of SBML models.
PMID:24903418
Bridging the gaps in systems biology.
PMID:24728588
Plant systems biology: insights, advances and challenges.
PMID:24671625
An online model composition tool for system biology models.
PMID:24006914
A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes.
PMID:23831062
D-Lactate production as a function of glucose metabolism in Saccharomyces cerevisiae.
PMID:23361949
Systems biology, bioinformatics, and biomarkers in neuropsychiatry.
PMID:23269912
Data management strategies for multinational large-scale systems biology projects.
PMID:23047157
A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells.
PMID:22969728
Elucidating the sources of β-catenin dynamics in human neural progenitor cells.
PMID:22952611
Condor-COPASI: high-throughput computing for biochemical networks.
PMID:22834945
OREMPdb: a semantic dictionary of computational pathway models.
PMID:22536973
What it takes to understand and cure a living system: computational systems biology and a systems biology-driven pharmacokinetics-pharmacodynamics platform.
PMID:22419971
Simplification of biochemical models: a general approach based on the analysis of the impact of individual species and reactions on the systems dynamics.
PMID:22390191
Creating interactive, web-based and data-enriched maps with the Systems Biology Graphical Notation.
PMID:22383037
Reproducible computational biology experiments with SED-ML--the Simulation Experiment Description Markup Language.
PMID:22172142
SABIO-RK--database for biochemical reaction kinetics.
PMID:22102587
Dupuytren's: a systems biology disease.
PMID:21943049
Retrieval, alignment, and clustering of computational models based on semantic annotations.
PMID:21772260
The logic of kinetic regulation in the thioredoxin system.
PMID:21266044
Consistent robustness analysis (CRA) identifies biologically relevant properties of regulatory network models.
PMID:21179566
Design principles of nuclear receptor signaling: how complex networking improves signal transduction.
PMID:21179018
Systematic integration of experimental data and models in systems biology.
PMID:21114840
Ranked retrieval of Computational Biology models.
PMID:20701772
BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models.
PMID:20587024
Simulating plant metabolic pathways with enzyme-kinetic models.
PMID:20118273
TIde: a software for the systematic scanning of drug targets in kinetic network models.
PMID:19840374
"Hot standards" for the thermoacidophilic archaeon Sulfolobus solfataricus.
PMID:19802714
Metabolic network discovery through reverse engineering of metabolome data.
PMID:19718266
Approaches to biosimulation of cellular processes.
PMID:19669467
Web-based applications for building, managing and analysing kinetic models of biological systems.
PMID:18805901
The model repository of the models of infectious disease agent study.
PMID:18632331
Systems biology towards life in silico: mathematics of the control of living cells.
PMID:18278498
A data integration approach for cell cycle analysis oriented to model simulation in systems biology.
PMID:17678529
Modeling biochemical transformation processes and information processing with Narrator.
PMID:17389034
Reactome: a knowledge base of biologic pathways and processes.
PMID:17367534
Thermodynamically feasible kinetic models of reaction networks.
PMID:17208985
Bringing metabolic networks to life: integration of kinetic, metabolic, and proteomic data.
PMID:17173670
Parameter estimate of signal transduction pathways.
PMID:17118160
Model storage, exchange and integration.
PMID:17118155
Mathematical modeling of intracellular signaling pathways.
PMID:17118154
Escalating model sizes and complexities call for standardized forms of representation.
PMID:16729046
Quantitative elementary mode analysis of metabolic pathways: the example of yeast glycolysis.
PMID:16584566
Cell-signalling dynamics in time and space.
PMID:16482094
BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems.
PMID:16381960
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway.
PMID:16293107