IPD-KIR - Killer-cell Immunoglobulin-like Receptors
Names
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IPD-KIR - Killer-cell Immunoglobulin-like Receptors
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
IPD-KIR
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Names
More detailed information about this field from each metasource.
IPD-KIR - Killer-cell Immunoglobulin-like Receptors
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
IPD-KIR
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Names
More detailed information about this field from each metasource.
IPD-KIR - Killer-cell Immunoglobulin-like Receptors
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
IPD-KIR
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
The database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.
Description
More detailed information about this field from each metasource.
The database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
The Immuno Polymorphism Database (IPD) is a set of specialist databases related to the study of polymorphic genes in the immune system. IPD currently consists of four databases: IPD-KIR, contains the allelic sequences of Killer-cell Immunoglobulin-like Receptors, IPD-MHC, is a database of sequences of the major histocompatibility complex of different species; IPD-HPA, alloantigens expressed only on platelets; and IPD-ESTAB, which provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologically characterised melanoma cell lines. The Killer-cell Immunoglobulin-like Receptors (KIR) are members of the immunoglobulin super family (IgSF) formerly called Killer-cell Inhibitory Receptors. KIRs have been shown to be highly polymorphic both at the allelic and haplotypic levels. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail, which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC), which encodes KIR genes, has been shown to be polymorphic, polygenic and complex in a manner similar to the MHC. This complexity in sequences has lead to the formation of the KIR nomenclature committee. The nomenclature committee is responsible for the naming of new allele sequences and produced its first report in 2002; this was complemented by the inclusion of the KIR data into IPD. The IPD-KIR Sequence Database contains the most up to date nomenclature and sequence alignments. Also available is an online submission tool that allows the submission of new and confirmatory KIR sequences directly to the KIR nomenclature committee. Future developments of the IPD-KIR section will involve working with the KIR nomenclature committee to provide nomenclature and tools for study of the complex haplotypes and genotypes currently seen in KIR research.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Webpage:
http://www.ebi.ac.uk/ipd/kir/Webpage
More detailed information about this field from each metasource.
http://www.ebi.ac.uk/ipd/kir/
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Licence:
Name: Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)Licence name
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Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Licence URL
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https://creativecommons.org/licenses/by-nd/4.0/
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
IPD--the Immuno Polymorphism Database
PMID: 23180793
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
IPD--the Immuno Polymorphism Database
PMID: 19875415
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications
More detailed information about this field from each metasource.
IPD--the Immuno Polymorphism Database
PMID: 23180793
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
IPD--the Immuno Polymorphism Database
PMID: 19875415
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
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IPD--the Immuno Polymorphism Database
PubMed citations: 92.
92 articles citing: IPD--the Immuno Polymorphism Database
Enhanced Extracellular Transfer of HLA-DQ Activates CD3+ Lymphocytes towards Compromised Treg Induction in Celiac Disease. PMID:35682780
Human Leukocyte Antigens in Pregnancy and Preeclampsia. PMID:35571013
KIR in Allogeneic Hematopoietic Stem Cell Transplantation: Need for a Unified Paradigm for Donor Selection. PMID:35242134
Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury. PMID:34931022
A Genome-Wide CRISPR/Cas9-Based Screen Identifies Heparan Sulfate Proteoglycans as Ligands of Killer-Cell Immunoglobulin-Like Receptors. PMID:34917099
Making a Killer: Selecting the Optimal Natural Killer Cells for Improved Immunotherapies. PMID:34777383
Comparative Analysis of SLA-1, SLA-2, and DQB1 Genetic Diversity in Locally-Adapted Kenyan Pigs and Their Wild Relatives, Warthogs. PMID:34564574
Genotyping of Eight Human Platelet Antigen Systems in Serbian Blood Donors: Foundation for Platelet Apheresis Registry. PMID:34539316
Killer-cell immunoglobulin-like receptor/human leukocyte antigen-C combination and 'great obstetrical syndromes' (Review). PMID:34504623
HLA-C and KIR permutations influence chronic obstructive pulmonary disease risk. PMID:34464355
Association of KIR Genes and MHC Class I Ligands with Atopic Dermatitis. PMID:34408014
Donor Killer Immunoglobulin Receptor Gene Content and Ligand Matching and Outcomes of Pediatric Patients with Juvenile Myelomonocytic Leukemia Following Unrelated Donor Transplantation. PMID:34407489
Relevance of Polymorphic KIR and HLA Class I Genes in NK-Cell-Based Immunotherapies for Adult Leukemic Patients. PMID:34359667
Using de novo assembly to identify structural variation of eight complex immune system gene regions. PMID:34343164
High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING. PMID:34339413
MiDAS-Meaningful Immunogenetic Data at Scale. PMID:34228721
HLA-E-restricted HIV-1-specific CD8+ T cell responses in natural infection. PMID:34228645
Sustained viremia suppression by SHIVSF162P3CN-recalled effector-memory CD8+ T cells after PD1-based vaccination. PMID:34125864
The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates. PMID:33013938
Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis. PMID:32804949
SOAPTyping: an open-source and cross-platform tool for sequence-based typing for HLA class I and II alleles. PMID:32640979
Polymorphic Region-Specific Antibody for Evaluation of Affinity-Associated Profile of Chimeric Antigen Receptor. PMID:32368617
Complex Linkage Disequilibrium Effects in HLA-DPB1 Expression and Molecular Mismatch Analyses of Transplantation Outcomes. PMID:32301906
High-Throughput Screening of Blood Donors for Twelve Human Platelet Antigen Systems Using Next-Generation Sequencing Reveals Detection of Rare Polymorphisms and Two Novel Protein-Changing Variants. PMID:32110192
Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools. PMID:31722398
MHC class I allele diversity in cynomolgus macaques of Vietnamese origin. PMID:31720104
MHC genotyping from rhesus macaque exome sequences. PMID:31321455
HLA-F on Autologous HIV-Infected Cells Activates Primary NK Cells Expressing the Activating Killer Immunoglobulin-Like Receptor KIR3DS1. PMID:31270222
Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation. PMID:31231370
Developing pharmacogenetic screening methods for an emergent country: Vietnam. PMID:31198488
The expanding role of systems immunology in decoding the T cell receptor repertoire. PMID:31106281
Novel Approach to Cell Surface Discrimination Between KIR2DL1 Subtypes and KIR2DS1 Identifies Hierarchies in NK Repertoire, Education, and Tolerance. PMID:31024561
Diversity of KIR, HLA Class I, and Their Interactions in Seven Populations of Sub-Saharan Africans. PMID:30918042
Computational KIR copy number discovery reveals interaction between inhibitory receptor burden and survival. PMID:30864318
Major histocompatibility complex class I diversity limits the repertoire of T cell receptors. PMID:30796191
Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors. PMID:30758400
Reduced bonobo MHC class I diversity predicts a reduced viral peptide binding ability compared to chimpanzees. PMID:30630404
Design and Validation of a Multiplex KIR and HLA Class I Genotyping Method Using Next Generation Sequencing. PMID:30619344
Extensive Alternative Splicing of KIR Transcripts. PMID:30564240
Cost-effective and fast KIR gene-content genotyping by multiplex melting curve analysis. PMID:30468002
Immuno-informatics Analysis to Identify Novel Vaccine Candidates and Design of a Multi-Epitope Based Vaccine Candidate Against Theileria parasites. PMID:30374343
Killer immunoglobulin-like receptor genotype did not correlate with response to anti-PD-1 antibody treatment in a Japanese cohort. PMID:30374122
Genotypic and Mechanistic Characterization of Subtype-Specific HIV Adaptation to Host Cellular Immunity. PMID:30305354
Bridging immunogenetics and immunoproteomics: Model positional scanning library analysis for Major Histocompatibility Complex class II DQ in Tursiops truncatus. PMID:30070993
Trans-Allelic Model for Prediction of Peptide:MHC-II Interactions. PMID:29988560
Nomenclature for the KIR of non-human species. PMID:29869002
Automated typing of red blood cell and platelet antigens: a whole-genome sequencing study. PMID:29780001
Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico. PMID:29093100
Identification of the major histocompatibility complex class-II DM and DO alleles in a cohort of northern pig-tailed macaques (Macaca leonina). PMID:29030661
Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation. PMID:28930983
Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B. PMID:28348269
Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes. PMID:28264973
Beyond the MHC: A canine model of dermatomyositis shows a complex pattern of genetic risk involving novel loci. PMID:28158183
Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C. PMID:28122963
The Impact of HLA Class I-Specific Killer Cell Immunoglobulin-Like Receptors on Antibody-Dependent Natural Killer Cell-Mediated Cytotoxicity and Organ Allograft Rejection. PMID:28066408
IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex. PMID:27899604
Identification of MHC Haplotypes Associated with Drug-induced Hypersensitivity Reactions in Cynomolgus Monkeys. PMID:27879435
Deciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology. PMID:27779741
Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts. PMID:27723741
Preferred SLA class I/class II haplotype combinations in German Landrace pigs. PMID:27484460
The influence of positive selection and trans-species evolution on DPB diversity in the golden snub-nosed monkeys (Rhinopithecus roxellana). PMID:27209173
A novel RNAseq-assisted method for MHC class I genotyping in a non-model species applied to a lethal vaccination-induced alloimmune disease. PMID:27188848
The major histocompatibility complex in Old World camelids and low polymorphism of its class II genes. PMID:26931144
The effects of killer cell immunoglobulin-like receptor (KIR) genes on susceptibility to HIV-1 infection in the Polish population. PMID:26888639
Sequence diversity between class I MHC loci of African native and introduced Bos taurus cattle in Theileria parva endemic regions: in silico peptide binding prediction identifies distinct functional clusters. PMID:26852329
Cloning, sequencing, and polymorphism analysis of novel classical MHC class I alleles in northern pig-tailed macaques (Macaca leonina). PMID:26782049
Bridging ImmunoGenomic Data Analysis Workflow Gaps (BIGDAWG): An integrated case-control analysis pipeline. PMID:26708359
Association of Killer Cell Immunoglobulin- Like Receptor Genes in Iranian Patients with Rheumatoid Arthritis. PMID:26658904
Comprehensive red blood cell and platelet antigen prediction from whole genome sequencing: proof of principle. PMID:26634332
Ancient Genetic Signatures of Orang Asli Revealed by Killer Immunoglobulin-Like Receptor Gene Polymorphisms. PMID:26565719
Discovery of novel MHC-class I alleles and haplotypes in Filipino cynomolgus macaques (Macaca fascicularis) by pyrosequencing and Sanger sequencing: Mafa-class I polymorphism. PMID:26349955
Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes. PMID:26311903
Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population. PMID:26292085
The assembly and characterisation of two structurally distinct cattle MHC class I haplotypes point to the mechanisms driving diversity. PMID:26227296
Major Histocompatibility Complex class IIB polymorphism in an ancient Spanish breed. PMID:26184839
Novel DRA alleles extracted from seven macaque cohorts. PMID:25626611
A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia. PMID:25561558
Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA. PMID:25485681
Association between CTL Precursor Frequency to HLA-C Mismatches and HLA-C Antigen Cell Surface Expression. PMID:25386183
Characterization of binding specificities of bovine leucocyte class I molecules: impacts for rational epitope discovery. PMID:25186069
KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand. PMID:25139336
Future directions of clinical laboratory evaluation of pregnancy. PMID:25042633
Use of "one-pot, mix-and-read" peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle. PMID:24775445
MHC polymorphism in Caribbean African green monkeys. PMID:24676686
Study of MHC class II region polymorphism in the Filipino cynomolgus macaque population. PMID:24569954
Mutational and structural analysis of KIR3DL1 reveals a lineage-defining allotypic dimorphism that impacts both HLA and peptide sensitivity. PMID:24563253
KIR3DL01 recognition of Bw4 ligands in the rhesus macaque: maintenance of Bw4 specificity since the divergence of apes and Old World monkeys. PMID:24453246
Analysis of maternal microchimerism in rhesus monkeys (Macaca mulatta) using real-time quantitative PCR amplification of MHC polymorphisms. PMID:24451553
Full-length novel MHC class I allele discovery by next-generation sequencing: two platforms are better than one. PMID:24241691
Allelic variation in KIR2DL3 generates a KIR2DL2-like receptor with increased binding to its HLA-C ligand. PMID:23686481
Alleles of the major histocompatibility complex play a role in the pathogenesis of pancreatic acinar atrophy in dogs. PMID:23604463
A database for curating the associations between killer cell immunoglobulin-like receptors and diseases in worldwide populations. PMID:23584834 -
IPD--the Immuno Polymorphism Database
PubMed citations: 70.
70 articles citing: IPD--the Immuno Polymorphism Database
Pangenome-based genome inference allows efficient and accurate genotyping across a wide spectrum of variant classes. PMID:35410384
ERAP, KIR, and HLA-C Profile in Recurrent Implantation Failure. PMID:34745129
Donor Killer Immunoglobulin Receptor Gene Content and Ligand Matching and Outcomes of Pediatric Patients with Juvenile Myelomonocytic Leukemia Following Unrelated Donor Transplantation. PMID:34407489
Targeting NK Cell Inhibitory Receptors for Precision Multiple Myeloma Immunotherapy. PMID:33304346
Human Platelet Antigen Datasets for Malays, Chinese, and Indians in Peninsular Malaysia. PMID:32539307
KIR and HLA-C genes in male infertility. PMID:32436047
Immunogenetics in stem cell donor registry work: The DKMS example (Part 2). PMID:32034894
The IPD Project: a centralised resource for the study of polymorphism in genes of the immune system. PMID:31641782
Nomenclature report 2019: major histocompatibility complex genes and alleles of Great and Small Ape and Old and New World monkey species. PMID:31624862
Monkeying Around: Using Non-human Primate Models to Study NK Cell Biology in HIV Infections. PMID:31191520
Fluctuating and Geographically Specific Selection Characterize Rapid Evolution of the Human KIR Region. PMID:31156615
Allele and haplotype frequencies of human platelet and leukocyte antigens in platelet donors. PMID:30758400
Design and Validation of a Multiplex KIR and HLA Class I Genotyping Method Using Next Generation Sequencing. PMID:30619344
Extensive Alternative Splicing of KIR Transcripts. PMID:30564240
Single-cell reconstruction of the early maternal-fetal interface in humans. PMID:30429548
Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop. PMID:30321631
KIR content genotypes associate with carriage of hepatitis B surface antigen, e antigen and HBV viral load in Gambians. PMID:29149205
AIDS in chimpanzees: the role of MHC genes. PMID:28695283
Integrated computational prediction and experimental validation identifies promiscuous T cell epitopes in the proteome of Mycobacterium bovis. PMID:28348866
2.7 million samples genotyped for HLA by next generation sequencing: lessons learned. PMID:28196473
Allelic Polymorphism Determines Surface Expression or Intracellular Retention of the Human NK Cell Receptor KIR2DL5A (CD158f). PMID:28144240
Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy. PMID:27815424
High-Accuracy HLA Type Inference from Whole-Genome Sequencing Data Using Population Reference Graphs. PMID:27792722
Genetic barriers in transplantation medicine. PMID:27683631
A novel RNAseq-assisted method for MHC class I genotyping in a non-model species applied to a lethal vaccination-induced alloimmune disease. PMID:27188848
Gene Association with Leprosy: A Review of Published Data. PMID:26793196
Comprehensive red blood cell and platelet antigen prediction from whole genome sequencing: proof of principle. PMID:26634332
Choosy Wolves? Heterozygote Advantage But No Evidence of MHC-Based Disassortative Mating. PMID:26610365
KIR Genes and Patterns Given by the A Priori Algorithm: Immunity for Haematological Malignancies. PMID:26495028
The killer-cell immunoglobulin-like receptors of macaques. PMID:26284482
KIR and HLA under pressure: evidences of coevolution across worldwide populations. PMID:26099314
Evaluation of host genetics on outcome of tuberculosis infection due to differences in killer immunoglobulin-like receptor gene frequencies and haplotypes. PMID:26077983
Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo. PMID:25867094
Time to seroconversion in HIV-exposed subjects carrying protective versus non protective KIR3DS1/L1 and HLA-B genotypes. PMID:25330014
Rapid induction of single donor chimerism after double umbilical cord blood transplantation preceded by reduced intensity conditioning: results of the HOVON 106 phase II study. PMID:25107890
Molecular characterization of swine leukocyte antigen class I genes by sequence-based and PCR-SSP method in Guizhou minipigs. PMID:25096513
A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples. PMID:24720548
Exome capture from saliva produces high quality genomic and metagenomic data. PMID:24708091
Improved pan-specific MHC class I peptide-binding predictions using a novel representation of the MHC-binding cleft environment. PMID:24447175
Copy number and nucleotide variation of the LILR family of myelomonocytic cell activating and inhibitory receptors. PMID:24257760
Identification and diversity of killer cell Ig-like receptors in Aotus vociferans, a New World monkey. PMID:24223188
Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans. PMID:24204327
KIR gene content in amerindians indicates influence of demographic factors. PMID:23451080
16(th) IHIW: population global distribution of killer immunoglobulin-like receptor (KIR) and ligands. PMID:23280119
Ligand specificity of Killer cell Immunoglobulin-like Receptors: a brief history of KIR. PMID:23269923
Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse. PMID:23211007
Diverse functionality among human NK cell receptors for the C1 epitope of HLA-C: KIR2DS2, KIR2DL2, and KIR2DL3. PMID:23189078
Allele-level haplotype frequencies and pairwise linkage disequilibrium for 14 KIR loci in 506 European-American individuals. PMID:23139747
Role of KIR3DS1 in human diseases. PMID:23125843
KIR2DL5: An Orphan Inhibitory Receptor Displaying Complex Patterns of Polymorphism and Expression. PMID:23060877
Natural selection on marine carnivores elaborated a diverse family of classical MHC class I genes exhibiting haplotypic gene content variation and allelic polymorphism. PMID:23001684
Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors. PMID:22948769
Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species. PMID:22526602
Cattle MHC nomenclature: is it possible to assign sequences to discrete class I genes? PMID:22419150
A shared MHC supertype motif emerges by convergent evolution in macaques and mice, but is totally absent in human MHC molecules. PMID:22322672
Review: Immunogenetics of human placentation. PMID:22177321
A community standard for immunogenomic data reporting and analysis: proposal for a STrengthening the REporting of Immunogenomic Studies statement. PMID:21988720
Vaccine-induced antibodies linked to bovine neonatal pancytopenia (BNP) recognize cattle major histocompatibility complex class I (MHC I). PMID:21878124
Conserved KIR allele-level haplotypes are altered by microvariation in individuals with European ancestry. PMID:21796155
Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques. PMID:21645414
KIR gene diversity in Mexican mestizos of San Luis Potosí. PMID:21638211
Screening and confirmatory testing of MHC class I alleles in pig-tailed macaques. PMID:21556859
KIR polymorphisms modulate peptide-dependent binding to an MHC class I ligand with a Bw6 motif. PMID:21423672
Spectrum of MHC class II variability in Darwin's finches and their close relatives. PMID:21273633
Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations. PMID:21214544
Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires. PMID:21209280
Interactions of NK cell receptor KIR3DL1*004 with chaperones and conformation-specific antibody reveal a functional folded state as well as predominant intracellular retention. PMID:21115737
Characterization of Mauritian cynomolgus macaque major histocompatibility complex class I haplotypes by high-resolution pyrosequencing. PMID:20882385
Thirty allele-level haplotypes centered around KIR2DL5 define the diversity in an African American population. PMID:20585770
The mosaic of KIR haplotypes in rhesus macaques. PMID:20204612
Tags:
Tags
More detailed information about this field from each metasource.
deoxyribonucleic acid
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
killer-cell immunoglobulin-like receptors
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
nucleic acid sequence
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
protein
metasource: Fairsharing.org
version: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
immunological databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Tags
More detailed information about this field from each metasource.
deoxyribonucleic acid
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
killer-cell immunoglobulin-like receptors
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
nucleic acid sequence
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
protein
metasource: Fairsharing.orgversion: FAIRsharing.org: IPD-KIR; IPD-KIR - Killer-cell Immunoglobulin-like Receptors; DOI: https://doi.org/10.25504/FAIRsharing.h87prx; Last edited: June 15, 2021, 1:58 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
immunological databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
dna killer-cell immunoglobulin-like receptors nucleic acid sequence protein immunology
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