IMGT database of human MHC
Provides a searchable repository of highly curated HLA sequences. The naming of these HLA genes and alleles and their quality control is the responsibility of the WHO Nomenclature Committee for Factors of the HLA System. Through the work of the HLA Informatics Group and in collaboration with the European Bioinformatics Institute, we are able to provide public access to this data.
Description
More detailed information about this field from each metasource.
Provides a searchable repository of highly curated HLA sequences. The naming of these HLA genes and alleles and their quality control is the responsibility of the WHO Nomenclature Committee for Factors of the HLA System. Through the work of the HLA Informatics Group and in collaboration with the European Bioinformatics Institute, we are able to provide public access to this data.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:08.554297
Webpage:
http://www.ebi.ac.uk/imgt/hla/Webpage
More detailed information about this field from each metasource.
http://www.ebi.ac.uk/imgt/hla/
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:08.554297
Publications:
Publications
More detailed information about this field from each metasource.
The IMGT/HLA database
PMID: 21071412
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:08.554297
Publications
More detailed information about this field from each metasource.
The IMGT/HLA database
PMID: 21071412
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:08.554297
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The IMGT/HLA database
PubMed citations: 119.
119 articles citing: The IMGT/HLA database
HLA imputation and its application to genetic and molecular fine-mapping of the MHC region in autoimmune diseases. PMID:34786601
Epitope-Based Immunoinformatic Approach on Heat Shock 70 kDa Protein Complex of Cryptococcus neoformans var. grubii. PMID:34471644
An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes. PMID:33074657
The deduced probable HLA-C*03:187-associated human leukocyte antigen haplotype (A*24:02-B*35:01-C*03:187-DRB1*11:01) revealed in Taiwanese unrelated hematopoietic bone marrow stem cell donors. PMID:32955526
Identification of Tumor Antigens in the HLA Peptidome of Patient-derived Xenograft Tumors in Mouse. PMID:32451349
Development of a novel monoclonal antibody that binds to most HLA-A allomorphs in a conformation-dependent yet peptide-promiscuous fashion. PMID:31970435
MHC class I allele diversity in cynomolgus macaques of Vietnamese origin. PMID:31720104
IPD-IMGT/HLA Database. PMID:31667505
HLA-A*29:01-B*07:05-C*15:29*DRB1*10:01-DQB1*05:01, a deduced probable human leukocyte antigen haplotype in association with a human leukocyte antigen-C low-incidence allele C*15:29 in Taiwanese individuals. PMID:31007487
Human leukocyte antigen-A*33:03-B*58:01-DRB1*15:140, a deduced probable human leukocyte antigen haplotype in association with a human leukocyte antigen low-incidence allele DRB1*15:140 in Taiwanese individuals: A case analysis. PMID:30692827
Non-classical human leucocyte antigens in ankylosing spondylitis: possible association with HLA-E and HLA-F. PMID:30018800
Does human leukocyte antigens sensitization matter for xenotransplantation? PMID:29913037
Human leukocyte antigen-A*24:02-B*40:247-C*03:04-DRB1*16:02, a deduced probable human leukocyte antigen haplotype associated with a low-incidence human leukocyte antigen allele B*40:247 in Taiwanese individuals: A case analysis. PMID:29875587
HLA genotyping by next-generation sequencing of complementary DNA. PMID:29179676
Potential Outer Membrane Protein Candidates for Vaccine Development Against the Pathogen Vibrio anguillarum: A Reverse Vaccinology Based Identification. PMID:29119233
Frequencies of HLA-A, B and DRB1 alleles in a large normal population living in the city of Mashhad, Northeastern Iran. PMID:29085586
Deduced probable HLA-C*07:359-associated human leukocyte antigen haplotypes found by case analysis of Taiwanese unrelated bone marrow hematopoietic stem cell donors. PMID:28757723
A deduced probable HLA-DRB1*16:35-associated HLA haplotype (A*11-B*13-DRB1*16:35) found in a case analysis of two Taiwanese unrelated bone marrow hematopoietic stem cell donors. PMID:28757709
Modeling Sequence-Dependent Peptide Fluctuations in Immunologic Recognition. PMID:28696685
How an alloreactive T-cell receptor achieves peptide and MHC specificity. PMID:28572406
2.7 million samples genotyped for HLA by next generation sequencing: lessons learned. PMID:28196473
Axial Disease in Psoriatic Arthritis study: defining the clinical and radiographic phenotype of psoriatic spondyloarthritis. PMID:27913376
Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors. PMID:27881843
A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces. PMID:27624308
Implications of the diversity of class I HLA associations in psoriatic arthritis. PMID:27455857
A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans. PMID:27409590
Comparison of a New In-House and Three Published HLA-B*15:02 Screening Methods for Prevention of Carbamazepine-Induced Severe Drug Reactions. PMID:27196420
Re-Examining Risk of Repeated HLA Mismatch in Kidney Transplantation. PMID:26888475
How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire. PMID:26884163
Genetics of Autoimmune Thyroiditis in Type 1 Diabetes Reveals a Novel Association With DPB1*0201: Data From the Type 1 Diabetes Genetics Consortium. PMID:26405068
Discovery of novel MHC-class I alleles and haplotypes in Filipino cynomolgus macaques (Macaca fascicularis) by pyrosequencing and Sanger sequencing: Mafa-class I polymorphism. PMID:26349955
Preclinical development of HIvax: Human survivin highly immunogenic vaccines. PMID:26042612
Genome-wide analysis links NFATC2 with asparaginase hypersensitivity. PMID:25987655
A population response analysis approach to assign class II HLA-epitope restrictions. PMID:25948811
The perfect storm: HLA antibodies, complement, FcγRs, and endothelium in transplant rejection. PMID:25801125
PharmGKB summary: very important pharmacogene information for human leukocyte antigen B. PMID:25647431
Factor VIII gene variants and inhibitor risk in African American hemophilia A patients. PMID:25617427
Immunogenic peptide discovery in cancer genomes. PMID:25588790
Understanding the complexity and malleability of T-cell recognition. PMID:25582337
High intralocus variability and interlocus recombination promote immunological diversity in a minimal major histocompatibility system. PMID:25526691
Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA. PMID:25485681
RADB: a database of rheumatoid arthritis-related polymorphisms. PMID:25228593
The risk of cutaneous adverse reactions among patients with the HLA-A* 31:01 allele who are given carbamazepine, oxcarbazepine or eslicarbazepine: a perspective review. PMID:25114785
Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. PMID:24997987
HLA diversity in the 1000 genomes dataset. PMID:24988075
A human-specific allelic group of the MHC DRB1 gene in primates. PMID:24928070
PharmGKB summary: uric acid-lowering drugs pathway, pharmacodynamics. PMID:24915143
HIV-1 subtype A gag variability and epitope evolution. PMID:24892852
Nonsynonymous substitution rate heterogeneity in the peptide-binding region among different HLA-DRB1 lineages in humans. PMID:24793785
Identification of 2127 new HLA class I alleles in potential stem cell donors from Germany, the United States and Poland. PMID:24571476
MHC2SKpan: a novel kernel based approach for pan-specific MHC class II peptide binding prediction. PMID:24564280
Co-occurrence of anaerobic bacteria in colorectal carcinomas. PMID:24450771
Improved pan-specific MHC class I peptide-binding predictions using a novel representation of the MHC-binding cleft environment. PMID:24447175
Association of HLA-B*51:01 with papillary thyroid carcinoma in the Chinese Han population of the Shandong coastal areas. PMID:24308748
Pathogen selection drives nonoverlapping associations between HLA loci. PMID:24225852
HIV-1 progression links with viral genetic variability and subtype, and patient's HLA type: analysis of a Nairobi-Kenyan cohort. PMID:24142198
Killer cell immunoglobulin-like receptor (KIR) genes and their HLA-C ligands in a Ugandan population. PMID:23974321
Equivalent T cell epitope promiscuity in ecologically diverse human pathogens. PMID:23951341
Structural and biophysical insights into the role of CD4 and CD8 in T cell activation. PMID:23885256
Major histocompatibility complex genomics and human disease. PMID:23875801
Genetic variability in markers of HLA-C expression in two diverse South African populations. PMID:23861805
HLA typing from RNA-seq data using hierarchical read weighting [corrected]. PMID:23840783
Integrating peptides' sequence and energy of contact residues information improves prediction of peptide and HLA-I binding with unknown alleles. PMID:23815611
Polymorphisms and tissue expression of the feline leukocyte antigen class I loci FLAI-E, FLAI-H, and FLAI-K. PMID:23812210
ATHLATES: accurate typing of human leukocyte antigen through exome sequencing. PMID:23748956
Routine performance and errors of 454 HLA exon sequencing in diagnostics. PMID:23731822
The HIV-1 pandemic: does the selective sweep in chimpanzees mirror humankind's future? PMID:23705941
Human leukocyte antigen DQ2/8 prevalence in non-celiac patients with gastrointestinal diseases. PMID:23674852
Evolutionary history of black grouse major histocompatibility complex class IIB genes revealed through single locus sequence-based genotyping. PMID:23617616
Rapid, scalable and highly automated HLA genotyping using next-generation sequencing: a transition from research to diagnostics. PMID:23557197
Clustering and alignment of polymorphic sequences for HLA-DRB1 genotyping. PMID:23555798
Current perspectives on the intensity of natural selection of MHC loci. PMID:23549729
PREDIVAC: CD4+ T-cell epitope prediction for vaccine design that covers 95% of HLA class II DR protein diversity. PMID:23409948
Recombinant structures expand and contract inter and intragenic diversification at the KIR locus. PMID:23394822
A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population. PMID:23392739
The complex transcriptional landscape of the anucleate human platelet. PMID:23323973
T-cell epitope vaccine design by immunoinformatics. PMID:23303307
16(th) IHIW: immunogenomic data-management methods. report from the immunogenomic data analysis working group (IDAWG). PMID:23280068
Diverse functionality among human NK cell receptors for the C1 epitope of HLA-C: KIR2DS2, KIR2DL2, and KIR2DL3. PMID:23189078
Non-random mating, parent-of-origin, and maternal-fetal incompatibility effects in schizophrenia. PMID:23177929
The antigen specific composition of melanoma tumor infiltrating lymphocytes? PMID:23162762
A rationally engineered anti-HIV peptide fusion inhibitor with greatly reduced immunogenicity. PMID:23147734
The resurgence and genetic implications of New World primates in biomedical research. PMID:23099234
The IMGT/HLA database. PMID:23080122
A sequence-based approach demonstrates that balancing selection in classical human leukocyte antigen (HLA) loci is asymmetric. PMID:23065702
Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1. PMID:23055555
Natural selection on marine carnivores elaborated a diverse family of classical MHC class I genes exhibiting haplotypic gene content variation and allelic polymorphism. PMID:23001684
HIV and HLA class I: an evolving relationship. PMID:22999948
Interrogating the major histocompatibility complex with high-throughput genomics. PMID:22976473
Predicting HLA class I non-permissive amino acid residues substitutions. PMID:22905104
Inference of selection based on temporal genetic differentiation in the study of highly polymorphic multigene families. PMID:22900006
Ultra-high resolution HLA genotyping and allele discovery by highly multiplexed cDNA amplicon pyrosequencing. PMID:22866951
Peptide binding to HLA-DP proteins at pH 5.0 and pH 7.0: a quantitative molecular docking study. PMID:22862845
Development of a novel in silico docking simulation model for the fine HIV-1 cytotoxic T lymphocyte epitope mapping. PMID:22848572
The effect of HLA polymorphisms on the recognition of Gag epitopes in HIV-1 CRF01_AE infection. PMID:22848569
Immunogenetics of the NKG2D ligand gene family. PMID:22843249
Pharmacology: A false sense of non-self. PMID:22739311
HLA class I expression in the human placenta. PMID:22717873
The immune epitope database: a historical retrospective of the first decade. PMID:22681406
Standard methods for the management of immunogenetic data. PMID:22665236
Direct identification of an HPV-16 tumor antigen from cervical cancer biopsy specimens. PMID:22566864
TEPITOPEpan: extending TEPITOPE for peptide binding prediction covering over 700 HLA-DR molecules. PMID:22383964
Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types. PMID:22323587
Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. PMID:22286218
Enrichment of variations in KIR3DL1/S1 and KIR2DL2/L3 among H1N1/09 ICU patients: an exploratory study. PMID:22216211
Amino acid position 11 of HLA-DRβ1 is a major determinant of chromosome 6p association with ulcerative colitis. PMID:22170232
NF-κB regulates MICA gene transcription in endothelial cell through a genetically inhibitable control site. PMID:22170063
Predictions versus high-throughput experiments in T-cell epitope discovery: competition or synergy? PMID:22149708
BGMUT: NCBI dbRBC database of allelic variations of genes encoding antigens of blood group systems. PMID:22084196
Non-classical MHC-Ι genes in chronic hepatitis B and hepatocellular carcinoma. PMID:22015712
A community standard for immunogenomic data reporting and analysis: proposal for a STrengthening the REporting of Immunogenomic Studies statement. PMID:21988720
Affinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complex. PMID:21900604
HLA-DP2 binding prediction by molecular dynamics simulations. PMID:21898654
The shaping of modern human immune systems by multiregional admixture with archaic humans. PMID:21868630
Dana-Farber repository for machine learning in immunology. PMID:21782820
Peptide binding prediction for the human class II MHC allele HLA-DP2: a molecular docking approach. PMID:21752305
PharmGKB summary: carbamazepine pathway. PMID:21738081
Variable NK cell receptors exemplified by human KIR3DL1/S1. PMID:21690332
Rhesus macaque KIR bind human MHC class I with broad specificity and recognize HLA-C more effectively than HLA-A and HLA-B. PMID:21614583
Tags:
Tags
More detailed information about this field from each metasource.
genetic variation
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:08.554297
proteins
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:08.554297
immunoproteins and antigens
metasource: bio.tools
version: extracted_at: 2022-11-04T11:27:08.554297
Tags
More detailed information about this field from each metasource.
genetic variation
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:08.554297
proteins
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:08.554297
immunoproteins and antigens
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:27:08.554297
genetic variation proteins immunoproteins and antigens
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