Tag: preclinical and clinical studies

The Stanford HIV Drug Resistance Database (HIVDB) is an essential resource for public health officials monitoring ADR and TDR, for scientists developing new ARV drugs, and for HIV care providers managing patients with HIVDR.

The goal of Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC) is to facilitate and coordinate the existing activities of the NHLBI Biorepository and the Data Repository and to expand their scope and usability to the sci ...

The human pluripotent stem cell registry (hPSCreg) is a public registry and data portal for human embryonic and induced pluripotent stem cell lines (hESC and hiPSC). The Registry provides comprehensive and standardized biological and legal informatio ...

The Open Data Commons for Traumatic Brain Injury (DC-TBI) was created by the TBI community to mitigate dark data in TBI research. The ODC-TBI also aims to increase transparency with individual-level data, enhance collaboration, facilitate advanced an ...

updated data repository of antimicrobial peptides | Browse, Create and Mining Antimicrobial Peptides | 157 new entries are added to in DRAMP. 33 entries are natural AMPs including 31 animal AMPs and 2 plant AMPs. 124 entries are synthetic AMPs | A br ...

PK-DB an open database for pharmacokinetics information from clinical trials as well as pre-clinical research. The focus of PK-DB is to provide high-quality pharmacokinetics data enriched with the required meta-information for computational modeling ...

The Clinical Trials Ontology (CTO) is also known as the Clinical Trial Ontology-Neurodegenerative Diseases (CTO-NDD), and describes clinical trials in the field of neurodegeneration. This resource has been created for use in the IMI-funded AETIONOMY ...

A database of global evaluation of SARS-CoV-2/hCoV-19 sequences. If you used GESS for scientific publication, we would appreciate citations to the following paper:.

The Clinical MetaData Ontology is designed to be used to classify Common Data Elements (CDEs) from different studies and clinical documents. CDEs can be efficiently searched, shared and reused by using our ontology.

The COVID-19 ontology covers the role of molecular and cellular entities in virus-host-interactions, in the virus life cycle, as well as a wide spectrum of medical and epidemiological concepts linked to COVID-19.

The FDA Adverse Event Reporting System (FAERS) is a database that contains information on adverse event and medication error reports submitted to FDA.

CORDITE is The Curated CORona Drug InTERactions Database for SARS-CoV-2. CORDITE aggregates all available knowledge on potential drugs for SARS-CoV-2. Since the outbreak in 2019, researchers are trying to find effective drugs against the SARS-CoV-2 v ...

CoronaVIR is a Web-Based Platform on Coronavirus Disease-19 to Maintain Predicted Diagnostic, Drug, and Vaccine Candidates.

Tool for the Unified Management of Clinical Information and Genetic Variants to Accelerate Variant Pathogenicity Classification.

A web resource for dendrimer pharmacokinetics investigation and prediction. Abstract: The development of nanomedicines currently suffers from a lack of efficient tools to predict pharmacokinetic behaviour without relying upon testing in large number ...

A Rapid and Accessible Tool That Exploits Genomic Data in Public Health and Clinical Microbiology Applications. Public databases for molecular typing and microbial genome diversity. A collection of open-access, curated databases that integrate popu ...

DrugRepV is a compendium of repurposed drugs and chemicals targeting epidemic and pandemic viruses.

Identifying subpathway signatures for individualized anticancer drug response by integrating multi-omics data | CancerDAP is a database molecularly characterizing subpathways involved in cellular response to 191 anticancer drugs | 1 Prospect the deta ...

Development and implementation of common data elements for venous thromboembolism research. Data Standards for Clinical Research. The International Society on Thrombosis and Haemostasis' Common Data Elements (CDE) provides pre-defined data standard ...

Vaccinomics and RNA-based therapeutics database for infectious hemorrhagic fever-causing mammarenaviruses.

Facilitating drug discovery with enriched comparative data of targeted agents.

Autophagy and Tumor Database (ATdb) is a database used to compile the published information concerning autophagy and tumor research. Such a database can be used for optaining an in-depth understanding of the complex correlations between autophagy and ...

A curated database of reconstructed individual patient-level data from 153 oncology clinical trials.

Cov19VaxKB: COVID-19 Vaccine Knowledge Base.

CMTTdb (The Cancer Molecular-Targeted Therapy database) is an integrated database to store relevant information about molecular targeted agents as well as their combinatorial approaches in clinical trials and studies for cancer treatment. It contains ...

A Database of Predicted T-cell Epitopes from Overly Expressed Proteins in Metastatic Cutaneous Melanoma | Browse and download predicted melanoma epitopes with high expected clinical efficacy in anti-cancer immunotherapy | This page acts as a gateway ...

A constructing a bilingual website with validated database for Herb and Western medicine interactions using Ginseng, Ginkgo and Dong Quai as examples.

A Comprehensive Database for Drug Repositioning Inspired by Experimental Knowledge | Drug Repositioning Drug repositioning, or the identification of new indications for approved therapeutic drugs, has gained substantial traction with both academics a ...

A comprehensive and curated portal for translational research.

A database and semantic analysis engine for literature, clinical trials and patents related to probiotics.

A database of biomarkers of cancer stem cells.

A library of peptide-based cancer vaccines and their clinical attributes, named CancerVaccine

A platform for evidence-based drug annotation for genetic variants in cancer

A database for anti-cancer compounds with targets and side effect profiles.

Virtual BioBanking (ViBiBa) for the DETECT multicenter trial program.

A Repository of Experimentally Characterized O-Glycoproteins to Facilitate Studies on O-Glycosylation. Numerous studies on cancer, biopharmaceuticals, and clinical trials have necessitated comprehensive and precise analysis of protein O-glycosylation ...

Applications of the Microphysiology Systems Database for Experimental ADME-Tox and Disease Models | The MPS-Db aggregates MPS data with linked preclinical and clinical databases for analysis in the context of human exposure. Built in tools enable the ...

COVIEdb is a database for potential immune epitopes of coronaviruses.

One-stop and comprehensive annotation system for individual cancer genome at multi-omics level.

Cancer Antigens Database (CAD) designed to facilitate users to perform a complete exploration of cancer antigens online.

The Integrated Aging Studies Databank and Repository (IASDR) IASDR serves as a resource for the scientific community to foster new scientific questions and analyses

APPECO (Applying Evidence with Confidence) is a tool that aims to help you find and use the best evidence for the rehabilitation of patients with Multiple Sclerosis.

An interactive retrieval system for clinical trial studies with context-dependent protocol elements. Clinical trial protocol includes all the steps that should be conducted in clinical trial and all clinical trial start with development of the proto ...

The Biomedical Research Hub (BRH) is a cloud-based and multifunctional web interface that provides a secure environment for discovery and analysis of scientific results and data.

Complementary and Alternative Medicine Clinical Trials Database for COVID-19 Disease (CoVAM) is a user-friendly database which gives update on registered clinical trials of complementary and alternative medicine on COVID-19 disease.

SAMS is a database and phenotyping tool for precision medicine. Physicians can enter clinical signs from the Human Phenotype Ontology as well complete diagnoses, and patients can be involved by sharing the symptoms they encounter.

The ReACH registry collected clinical information from 51 pediatric ACH patients during its six years of existence, corresponding to ~ 60% of ACH patients aged 3 months to 14 years that were anticipated to live in the Czechia and Slovak Republic

COVID-19 Knowledge Extractor (COKE) is a tool and a web portal to extract drug - target protein associations from the CORD-19 corpus of scientific publications on COVID-19.

A Genome-wide Positioning Systems Platform to Catalyze Multi-omics for Alzheimer’s Therapeutic Discovery. A Network-based multi-omics analysis informs Alzheimer's patient care and therapeutic development.

OpenTrials is a collaboration between Open Knowledge International and Dr Ben Goldacre from the University of Oxford DataLab. It aims to locate, match, and share all publicly accessible data and documents, on all trials conducted, on all medicines an ...

Molecular Prognostic Indicators in Cirrhosis Database for Clinical Context-Specific in Silico Prognostic Biomarker Validation. Molecular Prognostic Indicators in Cirrhosis. Database for clinical context-specific in silico prognostic biomarker valid ...

An integrative resource for investigating genetic model of drug response in cancer. An integrative database for investigating genetic model of drug response in cancer. iGMDR database collects predictive models of response for anti-cancer drugs. Th ...

PharmOmics is a A Species- and Tissue-specific Drug Signature Database and Online Tool for Toxicity Prediction and Drug Repurposing. It is a Web server for Identifying Pathological Pathways, Networks, and Key Regulators via Multidimensional Data Inte ...

CONSORT-TM is a corpus annotated with CONSORT checklist items, and studied baseline sentence classification methods as well as their combinations to recognize a subset of these items.

COVID-19 antibody therapeutics tracker is a global online database of antibody therapeutics for the prevention and treatment of COVID-19.

A database of exclusive proteins from Leishmania parasite. Leishmania Exclusive Protein Database. The Leishmania Exclusive Protein database (Leish-ExP) is a repository of protein sequences specific to five Leishmania species and genus. Leishmania i ...