STRING
Names
More detailed information about this field from each metasource.
STRING
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
metasource: bio.tools
version: extracted_at: 2022-11-04T11:31:43.096336
Known and Predicted Protein-Protein Interactions
metasource: re3data.org
version: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
string
metasource: bio.tools
version: extracted_at: 2022-11-04T11:31:43.096336
Names
More detailed information about this field from each metasource.
STRING
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
metasource: bio.tools
version: extracted_at: 2022-11-04T11:31:43.096336
Known and Predicted Protein-Protein Interactions
metasource: re3data.orgversion: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
string
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:31:43.096336
Other names: Known and Predicted Protein-Protein Interactions, string
Names
More detailed information about this field from each metasource.
STRING
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
metasource: bio.tools
version: extracted_at: 2022-11-04T11:31:43.096336
Known and Predicted Protein-Protein Interactions
metasource: re3data.orgversion: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
string
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:31:43.096336
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations.
Description
More detailed information about this field from each metasource.
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations.
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
Cellular life depends on a complex web of functional associations between biomolecules. Among these associations, protein–protein interactions are particularly important due to their versatility, specificity and adaptability. The STRING database aims to integrate all known and predicted associations between proteins, including both physical interactions as well as functional associations. To achieve this, STRING collects and scores evidence from a number of sources: (i) automated text mining of the scientific literature, (ii) databases of interaction experiments and annotated complexes/pathways, (iii) computational interaction predictions from co-expression and from conserved genomic context and (iv) systematic transfers of interaction evidence from one organism to another. STRING aims for wide coverage; the upcoming version 11.5 of the resource will contain more than 14 000 organisms. In this update paper, we describe changes to the text-mining system, a new scoring-mode for physical interactions, as well as extensive user interface features for customizing, extending and sharing protein networks. In addition, we describe how to query STRING with genome-wide, experimental data, including the automated detection of enriched functionalities and potential biases in the user's query data. The STRING resource is available online, at https://string-db.org/.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.
metasource: re3data.orgversion: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
A database of known and predicted protein-protein interactions. The database contains information from numerous sources, including experimental repositories, computational prediction methods and public text collections. STRING is regularly updated and gives a comprehensive view on protein-protein interactions currently available.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:31:43.096336
Webpage:
https://string-db.org/Webpage
More detailed information about this field from each metasource.
https://string-db.org/
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
http://string-db.org/
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:31:43.096336
Licence:
Name: Creative Commons Attribution 4.0 International (CC BY 4.0)Licence name
More detailed information about this field from each metasource.
Creative Commons Attribution 4.0 International (CC BY 4.0)
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
CC
metasource: re3data.orgversion: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
Licence URL
More detailed information about this field from each metasource.
https://creativecommons.org/licenses/by/4.0/
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
Publications:
(8)
Publications
More detailed information about this field from each metasource.
STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
PMID: 30476243
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
STRING v10: protein-protein interaction networks, integrated over the tree of life
PMID: 25352553
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible
PMID: 27924014
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
STRING v9.1: protein-protein interaction networks, with increased coverage and integration
PMID: 23203871
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
STRING 8--a global view on proteins and their functional interactions in 630 organisms
PMID: 18940858
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
SVD-phy: improved prediction of protein functional associations through singular value decomposition of phylogenetic profiles
PMID: 26614125
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
https://doi.org/10.1093/nar/gkaa1074
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
http://dx.doi.org/10.1093/nar/gku1003
metasource: bio.tools
version: extracted_at: 2022-11-04T11:31:43.096336
Publications
More detailed information about this field from each metasource.
STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
PMID: 30476243
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
STRING v10: protein-protein interaction networks, integrated over the tree of life
PMID: 25352553
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible
PMID: 27924014
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
STRING v9.1: protein-protein interaction networks, with increased coverage and integration
PMID: 23203871
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
STRING 8--a global view on proteins and their functional interactions in 630 organisms
PMID: 18940858
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
SVD-phy: improved prediction of protein functional associations through singular value decomposition of phylogenetic profiles
PMID: 26614125
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
https://doi.org/10.1093/nar/gkaa1074
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
http://dx.doi.org/10.1093/nar/gku1003
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:31:43.096336
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STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
PubMed citations: 4681.
4681 articles citing: STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
TP53-dependent toxicity of CRISPR/Cas9 cuts is differential across genomic loci and can confound genetic screening. PMID:35927263
Methods to capture proteomic and metabolomic signatures from cerebrospinal fluid and serum of healthy individuals. PMID:35922450
Multiple roles of apolipoprotein B mRNA editing enzyme catalytic subunit 3B (APOBEC3B) in human tumors: a pan-cancer analysis. PMID:35918642
Mechanism of Danhong Injection in the Treatment of Arrhythmia Based on Network Pharmacology, Molecular Docking, and In Vitro Experiments. PMID:35915792
Integrated Analysis of Gene Expression and Methylation Data to Identify Potential Biomarkers Related to Atherosclerosis Onset. PMID:35915606
Mapping the cell-membrane proteome of the SKBR3/HER2+ cell line to the cancer hallmarks. PMID:35913978
Comparisons of Metastatic Patterns, Survival Outcomes and Tumor Immune Microenvironment Between Young and Non-Young Breast Cancer Patients. PMID:35912097
RNA-seq Based Transcriptome Analysis Reveals The Cross-Talk of Macrophage and Adipocyte of Chicken Subcutaneous Adipose Tissue during The Embryonic and Post-Hatch Period. PMID:35911745
Icariin and Competing Endogenous RNA Network: A Potential Protective Strategy Against Contrast-Induced Acute Kidney Injury. PMID:35910780
RAB39B as a Chemosensitivity-Related Biomarker for Diffuse Large B-Cell Lymphoma. PMID:35910358
Identification and Verification of Potential Biomarkers in Gastric Cancer By Integrated Bioinformatic Analysis. PMID:35910202
The Construction and Analysis of Infiltrating Immune Cell and ceRNA Networks in Diabetic Foot Ulcer. PMID:35909542
Aspirin-Mediated Reset of Preeclamptic Placental Stem Cell Transcriptome - Implication for Stabilized Placental Function. PMID:35908144
Tenogenic induction of human adipose-derived stem cells by soluble tendon extracellular matrix: composition and transcriptomic analyses. PMID:35906661
Gene networks under circadian control exhibit diurnal organization in primate organs. PMID:35906476
Genetic variation as a long-distance modulator of RAD21 expression in humans. PMID:35906355
Integrative Bioinformatics Analysis Reveals CHEK1 and UBE2C as Luminal A Breast Cancer Subtype Biomarkers. PMID:35903365
Network Pharmacology and Molecular Docking on the Molecular Mechanism of Jiawei-Huang Lian-Gan Jiang Decoction in the Treatment of Colorectal Adenomas. PMID:35899228
Alzheimer's Disease Blood Biomarkers Associated With Neuroinflammation as Therapeutic Targets for Early Personalized Intervention. PMID:35899035
Blood transcriptome analysis revealing aging gene expression profiles in red panda. PMID:35898935
A microRNA Signature for the Diagnosis of Statins Intolerance. PMID:35897722
Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer. PMID:35896617
Identification of key genes and their association with immune infiltration in adipose tissue of obese patients: a bioinformatic analysis. PMID:35894174
Genome-Wide Identification of R2R3-MYB Transcription Factor and Expression Analysis under Abiotic Stress in Rice. PMID:35893632
LncRNA-Based Classification of Triple Negative Breast Cancer Revealed Inherent Tumor Heterogeneity and Vulnerabilities. PMID:35893227
Novel Treatment Approach for Aspergilloses by Targeting Germination. PMID:35893126
lncRNA-miRNA-mRNA ceRNA Network Involved in Sheep Prolificacy: An Integrated Approach. PMID:35893032
Quantitative Proteomics and Network Analysis of Differentially Expressed Proteins in Proteomes of Icefish Muscle Mitochondria Compared with Closely Related Red-Blooded Species. PMID:35892974
The Tropomyosin Family as Novel Biomarkers in Relation to Poor Prognosis in Glioma. PMID:35892971
GPX2 and BMP4 as Significant Molecular Alterations in The Lung Adenocarcinoma Progression: Integrated Bioinformatics Analysis. PMID:35892234
An accurate prediction model of digenic interaction for estimating pathogenic gene pairs of human diseases. PMID:35891796
Transcriptome Analysis Reveals Molecular Mechanisms under Salt Stress in Leaves of Foxtail Millet (Setaria italica L.). PMID:35890498
Interrelation between Stress Management and Secretion Systems of Ralstonia solanacearum: An In Silico Assessment. PMID:35889976
Plasmodium falciparum S-Adenosylmethionine Synthetase Is Essential for Parasite Survival through a Complex Interaction Network with Cytoplasmic and Nuclear Proteins. PMID:35889137
In Silico Genomic and Metabolic Atlas of Limosilactobacillus reuteri DSM 20016: An Insight into Human Health. PMID:35889060
Transcriptome Analysis of Intracellular Amastigotes of Clinical Leishmania infantum Lines from Therapeutic Failure Patients after Infection of Human Macrophages. PMID:35889023
Meta-Analysis of RNA Sequencing Data of Arabidopsis and Rice under Hypoxia. PMID:35888167
Multi-Level Biological Network Analysis and Drug Repurposing Based on Leukocyte Transcriptomics in Severe COVID-19: In Silico Systems Biology to Precision Medicine. PMID:35887528
In Silico Identification of lncRNAs Regulating Sperm Motility in the Turkey (Meleagris gallopavo L.). PMID:35887003
Gene Expression Changes of Murine Cortex Homeostasis in Response to Sleep Deprivation Hint Dysregulated Aging-like Transcriptional Responses. PMID:35884632
An Integrated Bioinformatics Analysis towards the Identification of Diagnostic, Prognostic, and Predictive Key Biomarkers for Urinary Bladder Cancer. PMID:35884419
Identification of Endoplasmic Reticulum Stress-Related Subtypes, Infiltration Analysis of Tumor Microenvironment, and Construction of a Prognostic Model in Colorectal Cancer. PMID:35884393
Acetylome and Succinylome Profiling of Edwardsiella tarda Reveals Key Roles of Both Lysine Acylations in Bacterial Antibiotic Resistance. PMID:35884095
A Method for Bridging Population-Specific Genotypes to Detect Gene Modules Associated with Alzheimer's Disease. PMID:35883662
Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma. PMID:35883595
Seminal-Plasma-Mediated Effects on Sperm Performance in Humans. PMID:35883590
Cyst stem cell lineage eIF5 non-autonomously prevents testicular germ cell tumor formation via eIF1A/eIF2γ-mediated pre-initiation complex. PMID:35883200
Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration. PMID:35882847
Aggregative trans-eQTL analysis detects trait-specific target gene sets in whole blood. PMID:35882830
Androgens in Patients With Luminal B and HER2 Breast Cancer Might Be a Biomarker Promoting Anti-PD-1 Efficacy. PMID:35880165
N- glycoproteomic profiling revealing novel coronavirus therapeutic targets potentially involved in Cepharanthine's intervention. PMID:35879945
RGS1 and related genes as potential targets for immunotherapy in cervical cancer: computational biology and experimental validation. PMID:35879796
Pathogenomic in silico approach identifies NSP-A and Fe-IIISBP as possible drug targets in Neisseria Meningitidis MC58 and development of pharmacophores as novel therapeutic candidates. PMID:35879631
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection. PMID:35879412
The PH Domain and C-Terminal polyD Motif of Phafin2 Exhibit a Unique Concurrence in Animals. PMID:35877899
Rare Carbon-Bridged Citrinin Dimers from the Starfish-Derived Symbiotic Fungus Penicillium sp. GGF16-1-2. PMID:35877736
Mechanisms of Action of Semen Ziziphi spinosae in the Treatment of Tourette Syndrome. PMID:35875687
ContactPFP: Protein function prediction using predicted contact information. PMID:35875419
Protocol for establishing a protein-protein interaction network using tandem affinity purification followed by mass spectrometry in mammalian cells. PMID:35874475
AP1G2 Affects Mitotic Cycles of Female and Male Gametophytes in Arabidopsis. PMID:35873977
Active ingredients and molecular targets of Taraxacum mongolicum against hepatocellular carcinoma: network pharmacology, molecular docking, and molecular dynamics simulation analysis. PMID:35873910
Chromatin Separation Regulators Predict the Prognosis and Immune Microenvironment Estimation in Lung Adenocarcinoma. PMID:35873497
Oncogenetic Function and Prognostic Value of DNA Topoisomerase II Alpha in Human Malignances: A Pan-Cancer Analysis. PMID:35873470
orsum: a Python package for filtering and comparing enrichment analyses using a simple principle. PMID:35870894
Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice. PMID:35866635
Mechanism of Action of Yin Nourishing and Heat Clearing Prescription in Treating Cough Variant Asthma Based on Network Pharmacology and Molecular Docking Verification. PMID:35866040
NTD-DR: Nonnegative tensor decomposition for drug repositioning. PMID:35862409
Glia Maturation Factor β as a Novel Independent Prognostic Biomarker and Potential Therapeutic Target of Kidney Renal Clear Cell Carcinoma. PMID:35860559
HIF1α: A Novel Biomarker with Potential Prognostic and Immunotherapy in Pan-cancer. PMID:35860430
Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability. PMID:35858913
Metformin and Gegen Qinlian Decoction boost islet α-cell proliferation of the STZ induced diabetic rats. PMID:35858880
Proximity interactome analysis of Lassa polymerase reveals eRF3a/GSPT1 as a druggable target for host-directed antivirals. PMID:35858434
Antibody-mediated blockade for galectin-3 binding protein in tumor secretome abrogates PDAC metastasis. PMID:35858411
Differentiated function and localisation of SPO11-1 and PRD3 on the chromosome axis during meiotic DSB formation in Arabidopsis thaliana. PMID:35857772
Quantitative Analysis of the Protein Methylome Reveals PARP1 Methylation is involved in DNA Damage Response. PMID:35847980
Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis. PMID:35847923
Comprehensive Pan-Cancer Analysis of TRPM8 in Tumor Metabolism and Immune Escape. PMID:35847920
Anti-colon Cancer Effects of Dendrobium officinale Kimura & Migo Revealed by Network Pharmacology Integrated With Molecular Docking and Metabolomics Studies. PMID:35847793
EspF of Enterohemorrhagic Escherichia coli Enhances Apoptosis via Endoplasmic Reticulum Stress in Intestinal Epithelial Cells: An Isobaric Tags for Relative and Absolute Quantitation-Based Comparative Proteomic Analysis. PMID:35847082
DOCK4 as a Potential Biomarker Associated with Immune Infiltration in Stomach Adenocarcinoma: A Database Analysis. PMID:35846794
Multi-Omics Analysis of Molecular Characteristics and Carcinogenic Effect of NFE2L3 in Pan-Cancer. PMID:35846126
Identification of Prefrontal Cortex and Amygdala Expressed Genes Associated With Sevoflurane Anesthesia on Non-human Primate. PMID:35845920
Excessive Sodium Intake Leads to Cardiovascular Disease by Promoting Sex-Specific Dysfunction of Murine Heart. PMID:35845798
Interaction With Fungi Promotes the Accumulation of Specific Defense Molecules in Orchid Tubers and May Increase the Value of Tubers for Biotechnological and Medicinal Applications: The Case Study of Interaction Between Dactylorhiza sp. and Tulasnella calospora. PMID:35845638
Bioinformatics analysis identifies diagnostic biomarkers and their correlation with immune infiltration in diabetic nephropathy. PMID:35845512
Ferroptosis and Autophagy-Related Genes in the Pathogenesis of Ischemic Cardiomyopathy. PMID:35845045
Differential Expression Profiles of mRNA and Noncoding RNA and Analysis of Competitive Endogenous RNA Regulatory Networks in Nonalcoholic Steatohepatitis. PMID:35844837
In-silico analysis of interacting pathways through KIM-1 protein interaction in diabetic nephropathy. PMID:35843953
Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates. PMID:35842572
Platelet proteome reveals features of cell death, antiviral response and viral replication in covid-19. PMID:35842415
Identification of a novel immune-inflammatory signature of COVID-19 infections, and evaluation of pharmacokinetics and therapeutic potential of RXn-02, a novel small-molecule derivative of quinolone. PMID:35841781
Light-induced asymmetries in embryonic retinal gene expression are mediated by the vascular system and extracellular matrix. PMID:35840576
In silico prediction of putative antimicrobial targets in Xanthomonas citri pv. punicae using genome subtraction approach. PMID:35838834
Identification and Validation of Autophagy-Related Genes in Primary Ovarian Insufficiency by Gene Expression Profile and Bioinformatic Analysis. PMID:35837294
Serum alpha-1-antitrypsin level in the severity prognosis of systemic lupus erythematosus patients: Systematic exploration of novel biomarker. PMID:35836976
Identification of Hub Genes and Therapeutic Agents for IgA Nephropathy Through Bioinformatics Analysis and Experimental Validation. PMID:35836957
Screening a novel six critical gene-based system of diagnostic and prognostic biomarkers in prostate adenocarcinoma patients with different clinical variables. PMID:35836886
Overexpressed SNRPB/D1/D3/E/F/G correlate with poor survival and immune infiltration in hepatocellular carcinoma. PMID:35836882
A systematic pan-cancer analysis identifies RIOK3 as an immunological and prognostic biomarker. PMID:35836879
SERPINE1 Gene Is a Reliable Molecular Marker for the Early Diagnosis of Aortic Dissection. PMID:35836829
Maternal-fetal stress and DNA methylation signatures in neonatal saliva: an epigenome-wide association study. PMID:35836289
Differential gene screening and bioinformatics analysis of epidermal stem cells and dermal fibroblasts during skin aging. PMID:35835980
Poxviruses package viral redox proteins in lateral bodies and modulate the host oxidative response. PMID:35834477
Identification of Key Genes and Potential Pathways Associated with Mastitis Induced by E. coli. PMID:35834114
Deep learning frameworks for protein-protein interaction prediction. PMID:35832624
Comprehensive Characterization of a Novel E3-Related Gene Signature With Implications in Prognosis and Immunotherapy of Low-Grade Gliomas. PMID:35832194
A functional reference map of the RNF8 interactome in cancer. PMID:35831895
Integrated transcriptomic and regulatory network analyses uncovers the role of let-7b-5p, SPIB, and HLA-DPB1 in sepsis. PMID:35831411
SARS-CoV-2 potential drugs, drug targets, and biomarkers: a viral-host interaction network-based analysis. PMID:35831333
The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment. PMID:35831295
Mislocalization of protein kinase A drives pathology in Cushing's syndrome. PMID:35830806
Identification of the shared gene signatures and pathways between polycystic ovary syndrome and endometrial cancer: An omics data based combined approach. PMID:35830453
Computational insights into missense mutations in HTT gene causing Huntington's disease and its interactome networks. PMID:35829908
The consequences of viral infection on host DNA damage response: a focus on SARS-CoVs. PMID:35829826
Potential ferroptosis-related diagnostic and prognostic biomarkers in laryngeal cancer. PMID:35829804
Gene Expression Analysis Reveals Age and Ethnicity Signatures Between Young and Old Adults in Human PBMC. PMID:35822054
Somatic Mutations Detected in Parkinson Disease Could Affect Genes With a Role in Synaptic and Neuronal Processes. PMID:35821807
Specialized Proresolving Mediators Protect Against Experimental Autoimmune Myocarditis by Modulating Ca2+ Handling and NRF2 Activation. PMID:35818504
Systems biology models to identify the influence of SARS-CoV-2 infections to the progression of human autoimmune diseases. PMID:35818398
EXTL3 could serve as a potential biomarker of prognosis and immunotherapy for prostate cancer and its potential mechanisms. PMID:35818069
Qin Huang formula enhances the effect of Adriamycin in B-cell lymphoma via increasing tumor infiltrating lymphocytes by targeting toll-like receptor signaling pathway. PMID:35818037
The human amniotic epithelium confers a bias to differentiate toward the neuroectoderm lineage in human embryonic stem cells. PMID:35815953
Network Pharmacology and Bioinformatics Methods Reveal the Mechanism of Berberine in the Treatment of Ischaemic Stroke. PMID:35815278
The Lifestyle Modifications and Endometrial Proteome Changes of Women With Polycystic Ovary Syndrome and Obesity. PMID:35813634
Pericyte-derived extracellular vesicle-mimetic nanovesicles ameliorate erectile dysfunction via lipocalin 2 in diabetic mice. PMID:35813481
Impaired Neurodevelopmental Genes in Slovenian Autistic Children Elucidate the Comorbidity of Autism With Other Developmental Disorders. PMID:35813072
The Role of P4HA1 in Multiple Cancer Types and its Potential as a Target in Renal Cell Carcinoma. PMID:35812752
Identification of Key Endometrial MicroRNAs and Their Target Genes Associated With Pathogenesis of Recurrent Implantation Failure by Integrated Bioinformatics Analysis. PMID:35812749
Comprehensive Analysis of VCAN Expression Profiles and Prognostic Values in HCC. PMID:35812745
Integrated Transcriptome Profiling Identifies Prognostic Hub Genes as Therapeutic Targets of Glioblastoma: Evidenced by Bioinformatics Analysis. PMID:35811900
TritiKBdb: A Functional Annotation Resource for Deciphering the Complete Interaction Networks in Wheat-Karnal Bunt Pathosystem. PMID:35806459
Evolutionary Analysis and Functional Identification of Clock-Associated PSEUDO-RESPONSE REGULATOR (PRRs) Genes in the Flowering Regulation of Roses. PMID:35806340
Heat Shock Alters the Proteomic Profile of Equine Mesenchymal Stem Cells. PMID:35806237
Transcriptome Profiling of the Dorsomedial Prefrontal Cortex in Suicide Victims. PMID:35806070
Identification of Candidate Genes Regulating Drought Tolerance in Pearl Millet. PMID:35805919
Identifying Lethal Dependencies with HUGE Predictive Power. PMID:35805023
Machine Learning Predictor of Immune Checkpoint Blockade Response in Gastric Cancer. PMID:35804967
The Prognostic Value of the Circulating Tumor Cell-Based Four mRNA Scoring System: A New Non-Invasive Setting for the Management of Bladder Cancer. PMID:35804889
Dietary Inclusion of Dried Chicory Root Affects Cecal Mucosa Proteome of Nursery Pigs. PMID:35804609
Genomic and proteomic characterization of two strains of Shigella flexneri 2 isolated from infants' stool samples in Argentina. PMID:35804311
Differential expression profile of plasma exosomal microRNAs in acute type A aortic dissection with acute lung injury. PMID:35804020
Identification of molecular mechanisms underlying the therapeutic effects of Xintong granule in coronary artery disease by a network pharmacology and molecular docking approach. PMID:35801781
The role of toll-like receptors (TLRs) in pan-cancer. PMID:35801728
HMOX1 Attenuates the Sensitivity of Hepatocellular Carcinoma Cells to Sorafenib via Modulating the Expression of ABC Transporters. PMID:35800617
High-Altitude Genetic Selection and Genome-Wide Association Analysis of Yield-Related Traits in Elymus sibiricus L. Using SLAF Sequencing. PMID:35800604
Deciphering the Crosstalk Mechanisms of Wheat-Stem Rust Pathosystem: Genome-Scale Prediction Unravels Novel Host Targets. PMID:35800602
Exploring the Mechanisms and Molecular Targets of Taohong Siwu Decoction for the Treatment of Androgenetic Alopecia Based on Network Analysis and Molecular Docking. PMID:35800455
Gasdermins in Innate Host Defense Against Entamoeba histolytica and Other Protozoan Parasites. PMID:35795683
Atlas of phenotypic, genotypic and geographical diversity present in the European traditional tomato. PMID:35795386
Identification of Immune-Related Gene Signature in Stanford Type A Aortic Dissection. PMID:35795203
Syringin exerts anti-breast cancer effects through PI3K-AKT and EGFR-RAS-RAF pathways. PMID:35794555
Atypical cyclic di-AMP signaling is essential for Porphyromonas gingivalis growth and regulation of cell envelope homeostasis and virulence. PMID:35794154
A network pharmacology approach to explore and validate the potential targets of ginsenoside on osteoporosis. PMID:35791093
Identification of genes and key pathways underlying the pathophysiological association between nonalcoholic fatty liver disease and atrial fibrillation. PMID:35790963
Highly perturbed genes and hub genes associated with type 2 diabetes in different tissues of adult humans: a bioinformatics analytic workflow. PMID:35788821
Altered mitochondrial microenvironment at the spotlight of musculoskeletal aging and Alzheimer's disease. PMID:35788655
A Comprehensive Pan-Cancer Analysis of the Tumorigenic Role of Matrix Metallopeptidase 7 (MMP7) Across Human Cancers. PMID:35785154
Chemotherapy- and Immune-Related Gene Panel in Prognosis Prediction and Immune Microenvironment of SCLC. PMID:35784467
Exposure of Keratinocytes to Candida Albicans in the Context of Atopic Milieu Induces Changes in the Surface Glycosylation Pattern of Small Extracellular Vesicles to Enhance Their Propensity to Interact With Inhibitory Siglec Receptors. PMID:35784319
The XTH Gene Family in Schima superba: Genome-Wide Identification, Expression Profiles, and Functional Interaction Network Analysis. PMID:35783982
Genome-Wide Characterization of Superoxide Dismutase (SOD) Genes in Daucus carota: Novel Insights Into Structure, Expression, and Binding Interaction With Hydrogen Peroxide (H2O2) Under Abiotic Stress Condition. PMID:35783965
Transcriptome Profiling and Network Analysis Provide Insights Into the Pathogenesis of Vulvar Lichen Sclerosus. PMID:35783265
Low-Cost Genetic and Clinical Predictors of Response and Toxicity of Platinum-Based Chemotherapy in Advanced Non-Small Cell Lung Cancer. PMID:35783235
Aedes aegypti Aag-2 Cell Proteome Modulation in Response to Chikungunya Virus Infection. PMID:35782121
Recognition of Key Genes in Human Anaplastic Thyroid Cancer via the Weighing Gene Coexpression Network. PMID:35782055
CRISPR/Cas9-based genome-wide screening of Dictyostelium. PMID:35780186
Genome doubling enabled the expansion of yeast vesicle traffic pathways. PMID:35780185
Metabolic modeling-based drug repurposing in Glioblastoma. PMID:35778411
Single-cell specific and interpretable machine learning models for sparse scChIP-seq data imputation. PMID:35776722
PHILM2Web: A high-throughput database of macromolecular host-pathogen interactions on the Web. PMID:35776535
Inner membrane complex proteomics reveals a palmitoylation regulation critical for intraerythrocytic development of malaria parasite. PMID:35775739
The Role of Egg Yolk in Modulating the Virulence of Salmonella Enterica Serovar Enteritidis. PMID:35774398
The Bioinformatic Study Uncovers Probable Critical Genes Involved in the Pathophysiology of Biliary Atresia. PMID:35774294
Identification of Hub Genes for Early Diagnosis and Predicting Prognosis in Colon Adenocarcinoma. PMID:35774271
POLQ suppresses genome instability and alterations in DNA repeat tract lengths. PMID:35774233
Identification of hub genes and regulatory networks in histologically unstable carotid atherosclerotic plaque by bioinformatics analysis. PMID:35773742
Molecular subtypes, prognostic and immunotherapeutic relevant gene signatures mediated by DNA methylation regulators in hepatocellular carcinoma. PMID:35771147
Icariside II Restores Vascular Smooth Muscle Cell Contractile Phenotype by Enhancing the Focal Adhesion Signaling Pathway in the Rat Vascular Remodeling Model. PMID:35770073
Exonuclease 1 is a Potential Diagnostic and Prognostic Biomarker in Hepatocellular Carcinoma. PMID:35769911
Clinical significance and potential regulatory mechanism of overexpression of pituitary tumor-transforming gene transcription factor in bladder cancer. PMID:35768832
Molecular characterization of low-grade serous ovarian carcinoma identifies genomic aberrations according to hormone receptor expression. PMID:35768582
Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions. PMID:35768426
Insights into the structural peculiarities of the N-terminal and receptor binding domains of the spike protein from the SARS-CoV-2 Omicron variant. PMID:35767919
The hyaluronan-related genes HAS2, HYAL1-4, PH20 and HYALP1 are associated with prognosis, cell viability and spheroid formation capacity in ovarian cancer. PMID:35767191
Studies of neurodegenerative diseases using Drosophila and the development of novel approaches for their analysis. PMID:35765969
Genome analysis and virulence gene expression profile of a multi drug resistant Salmonella enterica serovar Typhimurium ms202. PMID:35765034
The impact of rare germline variants on human somatic mutation processes. PMID:35764656
Network-based machine learning approach to predict immunotherapy response in cancer patients. PMID:35764641
The SKBR3 cell-membrane proteome reveals telltales of aberrant cancer cell proliferation and targets for precision medicine applications. PMID:35760832
G1/S restriction point coordinates phasic gene expression and cell differentiation. PMID:35760790
Laboratory evolution of synthetic electron transport system variants reveals a larger metabolic respiratory system and its plasticity. PMID:35760776
Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia. PMID:35759659
Dysregulation of Neuropeptide and Tau Peptide Signatures in Human Alzheimer's Disease Brain. PMID:35758417
Exploring the relationship between osteoporosis and polycystic ovary syndrome based on bioinformatics. PMID:35758378
Discovering Immune-Mediated Mechanisms of Gastric Carcinogenesis Through Single-Cell RNA Sequencing. PMID:35757757
Clinical Values of the Identified Hub Genes in Systemic Lupus Erythematosus. PMID:35757684
GPHB5 Is a Biomarker in Women With Metabolic Syndrome: Results From Cross-Sectional and Intervention Studies. PMID:35757403
The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens. PMID:35756970
Identification of key miRNAs and targeted genes involved in the progression of oral squamous cell carcinoma. PMID:35756810
Prognostic and Immunological Value of GNB4 in Gastric Cancer by Analyzing TCGA Database. PMID:35756485
The Analysis of Potential Diagnostic and Therapeutic Targets for the Occurrence and Development of Gastric Cancer Based on Bioinformatics. PMID:35756405
Aged Callus Skeletal Stem/Progenitor Cells Contain an Inflammatory Osteogenic Population With Increased IRF and NF-κB Pathways and Reduced Osteogenic Potential. PMID:35755815
Epidermal Immunity and Function: Origin in Neonatal Skin. PMID:35755808
Correlation Between Immune-Related Genes and Tumor-Infiltrating Immune Cells With the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer. PMID:35754838
Qishen Yiqi Dripping Pill Protects Diabetic Nephropathy by Inhibiting the PI3K-AKT Signaling Pathways in Rats. PMID:35754685
Transcriptome analysis uncovers the autophagy-mediated regulatory patterns of the immune microenvironment in dilated cardiomyopathy. PMID:35752958
A novel 7 RNA-based signature for prediction of prognosis and therapeutic responses of wild-type BRAF cutaneous melanoma. PMID:35751033
Calculating genetic risk for dysfunction in pleiotropic biological processes using whole exome sequencing data. PMID:35751013
Analysis of commonly expressed genes between first trimester fetal heart and placenta cell types in the context of congenital heart disease. PMID:35750800
Resistance of Dickeya solani strain IPO 2222 to lytic bacteriophage ΦD5 results in fitness tradeoffs for the bacterium during infection. PMID:35750797
Identification of critical genes and molecular pathways in COVID-19 myocarditis and constructing gene regulatory networks by bioinformatic analysis. PMID:35749386
Comprehensive Bioinformatics Analysis to Reveal Key RNA Targets and Hub Competitive Endogenous RNA Network of Keratoconus. PMID:35747602
The Therapeutic Potential of ADAMTS8 in Lung Adenocarcinoma without Targetable Therapy. PMID:35743687
Antibody Arrays Identified Cycle-Dependent Plasma Biomarker Candidates of Peritoneal Endometriosis. PMID:35743637
A Dual-Acting Nitric Oxide Donor and Phosphodiesterase 5 Inhibitor Activates Autophagy in Primary Skin Fibroblasts. PMID:35743299
HOXA9 Overexpression Contributes to Stem Cell Overpopulation That Drives Development and Growth of Colorectal Cancer. PMID:35743243
The RelB-BLNK Axis Determines Cellular Response to a Novel Redox-Active Agent Betamethasone during Radiation Therapy in Prostate Cancer. PMID:35742868
Network-Based Methods for Approaching Human Pathologies from a Phenotypic Point of View. PMID:35741843
Exome Sequencing Identifies Genetic Variants Associated with Extreme Manifestations of the Cardiovascular Phenotype in Marfan Syndrome. PMID:35741789
A Quantitative Proteomic Approach Explores the Possible Mechanisms by Which the Small Molecule Stemazole Promotes the Survival of Human Neural Stem Cells. PMID:35741576
Proteomic and Metabolomic Profiles of T Cell-Derived Exosomes Isolated from Human Plasma. PMID:35741093
Comprehensive bioinformatic analysis reveals a cancer-associated fibroblast gene signature as a poor prognostic factor and potential therapeutic target in gastric cancer. PMID:35739492
mGWAS-Explorer: Linking SNPs, Genes, Metabolites, and Diseases for Functional Insights. PMID:35736459
Inflammatory Breast Cancer: The Cytokinome of Post-Mastectomy Wound Fluid Augments Proliferation, Invasion, and Stem Cell Markers. PMID:35735628
Comprehensive Analysis of Expression and Prognostic Value of MS4As in Glioma. PMID:35734424
Bioinformatics-Led Discovery of Osteoarthritis Biomarkers and Inflammatory Infiltrates. PMID:35734177
Exploration of the Nurse Shark (Ginglymostoma cirratum) Plasma Immunoproteome Using High-Resolution LC-MS/MS. PMID:35734164
Many kinds of oxidized proteins are present more in the urine of the elderly. PMID:35733114
Specificity Analysis of Protein Methyltransferases and Discovery of Novel Substrates Using SPOT Peptide Arrays. PMID:35733022
NTN4 as a prognostic marker and a hallmark for immune infiltration in breast cancer. PMID:35732855
RNase III CLASH in MRSA uncovers sRNA regulatory networks coupling metabolism to toxin expression. PMID:35732654
Proteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death. PMID:35732625
Deepening the knowledge of rare diseases dependent on angiogenesis through semantic similarity clustering and network analysis. PMID:35731990
Systematic inference of indirect transcriptional regulation by protein kinases and phosphatases. PMID:35731801
Sleep Loss Causes Dysfunction in Murine Extraorbital Lacrimal Glands. PMID:35731510
Identification of key apoptosis-related genes and immune infiltration in the pathogenesis of psoriasis. PMID:35729678
Overexpressed VDAC1 in breast cancer as a novel prognostic biomarker and correlates with immune infiltrates. PMID:35729567
Integrative transcriptome-wide analysis of atopic dermatitis for drug repositioning. PMID:35729261
Presence of Blastocystis in gut microbiota is associated with cognitive traits and decreased executive function. PMID:35729225
A comprehensive bioinformatics analysis to identify potential prognostic biomarkers among CC and CXC chemokines in breast cancer. PMID:35725915
Multi-Omics Integration and Network Analysis Reveal Potential Hub Genes and Genetic Mechanisms Regulating Bovine Mastitis. PMID:35723402
The combined use of acetazolamide and Rhodiola in the prevention and treatment of altitude sickness. PMID:35722398
Network pharmacological analysis of active components of Tongqiao Huoxue Decoction in the treatment of intracerebral hemorrhage. PMID:35722393
Functions of three ubiquitin-conjugating enzyme 2 genes in hepatocellular carcinoma diagnosis and prognosis. PMID:35721293
DACPGTN: Drug ATC Code Prediction Method Based on Graph Transformer Network for Drug Discovery. PMID:35721178
CLP1 is a Prognosis-Related Biomarker and Correlates With Immune Infiltrates in Rheumatoid Arthritis. PMID:35721104
BPTF activates the MAPK pathway through coexpression with Raf1 to promote proliferation of T-cell lymphoma. PMID:35720479
Three Oxidative Stress-Related Genes That Associate Endometrial Immune Cells Are Considered as Potential Biomarkers for the Prediction of Unexplained Recurrent Implantation Failure. PMID:35720403
Differential Gene Expression and Weighted Correlation Network Dynamics in High-Throughput Datasets of Prostate Cancer. PMID:35719950
Comprehensive Analysis of Potential ceRNA Network and Different Degrees of Immune Cell Infiltration in Acute Respiratory Distress Syndrome. PMID:35719385
In silico drug repurposing against SARS-CoV-2 using an integrative transcriptomic profiling approach: Hydrocortisone and Benzhydrocodone as potential drug candidates against COVID-19. PMID:35718334
Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation. PMID:35717488
Regulatory T Cell-Related Gene Indicators in Pulmonary Hypertension. PMID:35712711
Immunohistochemistry and Bioinformatics Identify GPX8 as a Potential Prognostic Biomarker and Target in Human Gastric Cancer. PMID:35712475
Differential Expression of Genes Regulating Store-operated Calcium Entry in Conjunction With Mitochondrial Dynamics as Potential Biomarkers for Cancer: A Single-Cell RNA Analysis. PMID:35711942
Identification of Core Genes and Screening of Potential Targets in Intervertebral Disc Degeneration Using Integrated Bioinformatics Analysis. PMID:35711934
DNA Methylation Analysis of Turner Syndrome BAV. PMID:35711915
3,3'-Diindolylmethane plus Eflornithine suppress DNA Replication and Cell Cycle in Esophageal Squamous Cell Carcinoma in vivo. PMID:35711839
New Clues to Prognostic Biomarkers of Four Hematological Malignancies. PMID:35711821
Immune Cell Infiltration Characteristics of Pigmented Villous Nodular Synovitis and Prediction of Potential Diagnostic Markers Based on Bioinformatics. PMID:35711523
A systematic review of molecular alterations in invasive non-functioning pituitary adenoma. PMID:35711030
A 16th century Escherichia coli draft genome associated with an opportunistic bile infection. PMID:35710940
Integrated analysis reveals the pivotal interactions between immune cells in the melanoma tumor microenvironment. PMID:35710862
Identification of HOX signatures contributing to oral cancer phenotype. PMID:35710803
Genetic pain loss disorders. PMID:35710757
Mass spectrometry-based draft of the mouse proteome. PMID:35710609
Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform. PMID:35710324
Lower Expression of TWEAK is Associated with Poor Survival and Dysregulate TIICs in Lung Adenocarcinoma. PMID:35707713
Reconstruction of gene innovation associated with major evolutionary transitions in the kingdom Fungi. PMID:35706021
Comprehensive bioinformatics analysis of susceptibility genes for developmental dysplasia of the hip. PMID:35702583
Bioinformatics prediction of potential mechanisms and biomarkers underlying dilated cardiomyopathy. PMID:35702326
IL-4 and CCR7 play an important role in the development of keloids in patients with a family history. PMID:35702126
Network pharmacology and molecular docking approach to elucidate the mechanisms of Liuwei Dihuang pill in diabetic osteoporosis. PMID:35701780
Transcriptional profile changes after treatment of ischemia reperfusion injury-induced kidney fibrosis with 18β-glycyrrhetinic acid. PMID:35699239
Gene expression profiling and protein-protein interaction analysis reveals the dynamic role of MCM7 in Alzheimer's disorder and breast cancer. PMID:35698583
A novel method for assessing and measuring homophily in networks through second-order statistics. PMID:35697749
Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma. PMID:35697697
Spinal Cord Injury Impairs Lung Immunity in Mice. PMID:35697382
Monocyte Transcriptional Responses to Mycobacterium tuberculosis Associate with Resistance to Tuberculin Skin Test and Interferon Gamma Release Assay Conversion. PMID:35695527
Rare Variants in Inborn Errors of Immunity Genes Associated With Covid-19 Severity. PMID:35694544
Grapefruit Juice Flavanones Modulate the Expression of Genes Regulating Inflammation, Cell Interactions and Vascular Function in Peripheral Blood Mononuclear Cells of Postmenopausal Women. PMID:35694160
Identification of Hub Genes in Colorectal Adenocarcinoma by Integrated Bioinformatics. PMID:35693937
Bioinformatic Analysis Identifying PSMB 1/2/3/4/6/8/9/10 as Prognostic Indicators in Clear Cell Renal Cell Carcinoma. PMID:35693739
Evaluation of NOTCH family genes' expression and prognostic value in prostate cancer. PMID:35693717
Decoding the Mechanism behind the Pathogenesis of the Focal Segmental Glomerulosclerosis. PMID:35693262
A Conserved Long Intergenic Non-coding RNA Containing snoRNA Sequences, lncCOBRA1, Affects Arabidopsis Germination and Development. PMID:35693169
Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis. PMID:35692536
Gene Expression Profiles of the Aging Rat Hippocampus Imply Altered Immunoglobulin Dynamics. PMID:35692421
Comprehensive Analysis of Prognostic Value and Immune Infiltration of NLRC4 and CASP1 in Colorectal Cancer. PMID:35692355
Multiomic analysis reveals cell-type-specific molecular determinants of COVID-19 severity. PMID:35690068
MIR146A and ADIPOQ genetic variants are associated with birth weight in relation to gestational age: a cohort study. PMID:35689735
Omics-based integrated analysis identified IKZF2 as a biomarker associated with lupus nephritis. PMID:35688845
Identification of four serum miRNAs as potential markers to screen for thirteen cancer types. PMID:35687572
The dsRBP Staufen2 governs RNP assembly of neuronal Argonaute proteins. PMID:35687120
Metformin Prevents Key Mechanisms of Obesity-Related Complications in Visceral White Adipose Tissue of Obese Pregnant Mice. PMID:35684088
Genome-Wide Identification and Analysis of Ariadne Gene Family Reveal Its Genetic Effects on Agronomic Traits of Brassica napus. PMID:35682945
Genome-Wide Identification of Long Noncoding RNA and Their Potential Interactors in ISWI Mutants. PMID:35682924
Role of Nucleolin in Endometrial Precancerous Hyperplasia and Carcinogenesis: Ex Vivo and In Silico Study. PMID:35682908
Copy Number Variations Contribute to Intramuscular Fat Content Differences by Affecting the Expression of PELP1 Alternative Splices in Pigs. PMID:35681846
Loss of CHGA Protein as a Potential Biomarker for Colon Cancer Diagnosis: A Study on Biomarker Discovery by Machine Learning and Confirmation by Immunohistochemistry in Colorectal Cancer Tissue Microarrays. PMID:35681650
An epigenome-wide study of DNA methylation profiles and lung function among American Indians in the Strong Heart Study. PMID:35681244
Virtual ChIP-seq: predicting transcription factor binding by learning from the transcriptome. PMID:35681170
Evolutionary action of mutations reveals antimicrobial resistance genes in Escherichia coli. PMID:35680894
Discovering gene regulatory networks of multiple phenotypic groups using dynamic Bayesian networks. PMID:35679575
Posttranscriptional Regulation in Response to Different Environmental Stresses in Campylobacter jejuni. PMID:35678555
Proteomic dataset of Listeria monocytogenes exposed to sublethal concentrations of free and nanoencapsulated nisin. PMID:35677622
Identification of an Autophagy-Related Signature Based on Whole Bone Marrow Sequencing for the Prognosis and Immune Microenvironment Characterization of Multiple Myeloma. PMID:35677537
Primary Hepatoid Adenocarcinoma of the Lung: A Systematic Literature Review. PMID:35676912
[Huangqi Sijunzi decoction for treating cancer-related fatigue in breast cancer patients: a randomized trial and network pharmacology study]. PMID:35673907
RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells. PMID:35673573
Exploring the comorbidity mechanisms between asthma and idiopathic pulmonary fibrosis and the pharmacological mechanisms of Bu-Shen-Yi-Qi decoction therapy via network pharmacology. PMID:35672815
Network pharmacology and in vivo experiments reveal the pharmacological effects and molecular mechanisms of Simiao Powder in prevention and treatment for gout. PMID:35672755
Meta-analysis across Nellore cattle populations identifies common metabolic mechanisms that regulate feed efficiency-related traits. PMID:35672696
Network pharmacology and experimental verification based research into the effect and mechanism of Aucklandiae Radix-Amomi Fructus against gastric cancer. PMID:35672352
Network assisted analysis of de novo variants using protein-protein interaction information identified 46 candidate genes for congenital heart disease. PMID:35671298
Identification of Biomarkers of Autophagy-Related Genes Between Early and Advanced Carotid Atherosclerosis. PMID:35669594
Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress. PMID:35669581
The Vulnerability to Methamphetamine Dependence and Genetics: A Case-Control Study Focusing on Genetic Polymorphisms at Chromosomal Region 5q31.3. PMID:35669261
Identification and Expression Analysis of Calcium-Dependent Protein Kinases Gene Family in Potato Under Drought Stress. PMID:35669192
Huoxue Qianyang Qutan Recipe Protects against Early Renal Damage Induced by Obesity-Related Hypertension via the SIRT1/NF-κB/IL-6 Pathway: Integrating Network Pharmacology and Experimental Validation-Based Strategy. PMID:35668772
STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway. PMID:35668064
Signatures of glial activity can be detected in the CSF proteome. PMID:35666874
Predicting which genes will respond to transcription factor perturbations. PMID:35666184
Integrative analysis and prediction of human R-loop binding proteins. PMID:35666183
Connections for Matters of the Heart: Network Medicine in Cardiovascular Diseases. PMID:35665246
Clozapine Long-Term Treatment Might Reduce Epigenetic Age Through Hypomethylation of Longevity Regulatory Pathways Genes. PMID:35664466
Comprehensive Analysis of the Immune Cell Infiltration Landscape and Immune-Related Methylation in Retinoblastoma. PMID:35664300
Single-Cell RNA-seq Analysis Reveals Cellular Functional Heterogeneity in Dermis Between Fibrotic and Regenerative Wound Healing Fates. PMID:35664010
Altered Cellular Immunity and Differentially Expressed Immune-Related Genes in Patients With Systemic Sclerosis-Associated Pulmonary Arterial Hypertension. PMID:35663995
Sex-Specific Transcriptomic Signatures in Brain Regions Critical for Neuropathic Pain-Induced Depression. PMID:35663269
Identification of a Ferroptosis-Related Prognostic Signature in Sepsis via Bioinformatics Analyses and Experiment Validation. PMID:35663048
PEPPI: Whole-proteome Protein-protein Interaction Prediction through Structure and Sequence Similarity, Functional Association, and Machine Learning. PMID:35662463
Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus. PMID:35659263
WeCoNET: a host-pathogen interactome database for deciphering crucial molecular networks of wheat-common bunt cross-talk mechanisms. PMID:35658913
Salvianolic Acid B Alleviates Limb Ischemia in Mice via Promoting SIRT1/PI3K/AKT Pathway-Mediated M2 Macrophage Polarization. PMID:35656466
Prognostic and Immunological Role of PPP1R14A as a Pan-Cancer Analysis Candidate. PMID:35656324
Sleep and Late-Onset Alzheimer's Disease: Shared Genetic Risk Factors, Drug Targets, Molecular Mechanisms, and Causal Effects. PMID:35656316
Prognostic and Immune Implications of a Novel Pyroptosis-Related Five-Gene Signature in Breast Cancer. PMID:35656090
Establishment and Verification of a Gene Signature for Diagnosing Type 2 Diabetics by WGCNA, LASSO Analysis, and In Vitro Experiments. PMID:35655479
Expediting knowledge acquisition by a web framework for Knowledge Graph Exploration and Visualization (KGEV): case studies on COVID-19 and Human Phenotype Ontology. PMID:35655307
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation. PMID:35654975
Identification of Novel Characteristics in TP53-Mutant Hepatocellular Carcinoma Using Bioinformatics. PMID:35651938
Spatial Mapping of Plant N-Glycosylation Cellular Heterogeneity Inside Soybean Root Nodules Provided Insights Into Legume-Rhizobia Symbiosis. PMID:35651768
Identification of hub pathways and drug candidates in gastric cancer through systems biology. PMID:35650297
Snake venom gene expression is coordinated by novel regulatory architecture and the integration of multiple co-opted vertebrate pathways. PMID:35649579
Differential Etv2 threshold requirement for endothelial and erythropoietic development. PMID:35649376
BETA: a comprehensive benchmark for computational drug-target prediction. PMID:35649342
In Silico Integration of Transcriptome and Interactome Predicts an ETP-ALL-Specific Transcriptional Footprint that Decodes its Developmental Propensity. PMID:35646901
Resveratrol Ameliorates Lipopolysaccharide-Induced Sudden Sensorineural Hearing Loss in In Vitro Model through Multitarget Antiapoptotic Mechanism Based on Network Pharmacology and Molecular Docking. PMID:35646137
Identification and Verification of Feature Biomarkers Associated With Immune Cells in Dilated Cardiomyopathy by Bioinformatics Analysis. PMID:35646094
Deciphering the Effects and Mechanisms of Yi-Fei-San-Jie-pill on Non-Small Cell Lung Cancer With Integrating Network Target Analysis and Experimental Validation. PMID:35645820
Proteomic and Morphological Profiling of Mice Ocular Tissue During High-altitude Acclimatization Process: An Animal Study at Lhasa. PMID:35645575
Histological and Top-Down Proteomic Analyses of the Visual Pathway in the Cuprizone Demyelination Model. PMID:35644788
Mosaic loss of chromosome Y in peripheral blood cells is associated with age-related macular degeneration in men. PMID:35642040
Proteomic analysis of the ATP synthase interactome in notothenioids highlights a pathway that inhibits ceruloplasmin production. PMID:35639858
PRECOGx: exploring GPCR signaling mechanisms with deep protein representations. PMID:35639758
Using plasma proteomics to investigate viral infections of the central nervous system including patients with HIV-associated neurocognitive disorders. PMID:35639337
Amentoflavone derivatives significantly act towards the main protease (3CLPRO/MPRO) of SARS-CoV-2: in silico admet profiling, molecular docking, molecular dynamics simulation, network pharmacology. PMID:35639226
High-intensity interval training remodels the proteome and acetylome of human skeletal muscle. PMID:35638262
Identification of Ferroptosis-Related Hub Genes and Their Association with Immune Infiltration in Chronic Obstructive Pulmonary Disease by Bioinformatics Analysis. PMID:35637927
Cystatin SN promotes epithelial-mesenchymal transition and serves as a prognostic biomarker in lung adenocarcinoma. PMID:35637432
Analysis of multiple databases identifies crucial genes correlated with prognosis of hepatocellular carcinoma. PMID:35637248
Single-Cell RNA-seq Analysis Reveals Dysregulated Cell-Cell Interactions in a Tumor Microenvironment Related to HCC Development. PMID:35634447
CD20+CD22+ADAM28+ B Cells in Tertiary Lymphoid Structures Promote Immunotherapy Response. PMID:35634306
Comparative Proteomic Analysis Reveals Mx1 Inhibits Senecavirus A Replication in PK-15 Cells by Interacting with the Capsid Proteins VP1, VP2 and VP3. PMID:35632606
The Cell Surface Heparan Sulfate Proteoglycan Syndecan-3 Promotes Ovarian Cancer Pathogenesis. PMID:35628603
An Integrated Approach Reveals DNA Damage and Proteotoxic Stress as Main Effects of Proton Radiation in S. cerevisiae. PMID:35628303
Soyasapogenol C from Fermented Soybean (Glycine Max) Acting as a Novel AMPK/PPARα Dual Activator Ameliorates Hepatic Steatosis: A Novel SANDA Methodology. PMID:35628280
Identification of Hub Genes and Immune Infiltration in Pediatric Biliary Atresia by Comprehensive Bioinformatics Analysis. PMID:35626874
Multi-Omics Analyses to Identify FCGBP as a Potential Predictor in Head and Neck Squamous Cell Carcinoma. PMID:35626334
Angiopoietin-1 Upregulates Cancer Cell Motility in Colorectal Cancer Liver Metastases through Actin-Related Protein 2/3. PMID:35626145
Central and Peripheral Immune Dysregulation in Posttraumatic Stress Disorder: Convergent Multi-Omics Evidence. PMID:35625844
Immune-Related Protein Interaction Network in Severe COVID-19 Patients toward the Identification of Key Proteins and Drug Repurposing. PMID:35625619
Insights into a Cancer-Target Demethylase: Substrate Prediction through Systematic Specificity Analysis for KDM3A. PMID:35625569
Multi-Omic Data Improve Prediction of Personalized Tumor Suppressors and Oncogenes. PMID:35620468
Mechanism of Fructus Mume Pills Underlying Their Protective Effects in Rats with Acetic Acid-Inducedulcerative Colitis via the Regulation of Inflammatory Cytokines and the VEGF-PI3K/Akt-eNOS Signaling Pathway. PMID:35620404
Scrutinizing Deleterious Nonsynonymous SNPs and Their Effect on Human POLD1 Gene. PMID:35620275
Intercellular Communication-Related Molecular Subtypes and a Gene Signature Identified by the Single-Cell RNA Sequencing Combined with a Transcriptomic Analysis. PMID:35620271
Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation. PMID:35618845
Integrated bioinformatics and statistical approaches to explore molecular biomarkers for breast cancer diagnosis, prognosis and therapies. PMID:35617355
CDC25C is a prognostic biomarker and correlated with mitochondrial homeostasis in pancreatic adenocarcinoma. PMID:35615982
Comprehensive Analysis of Prognostic and immune infiltrates for FOXPs Transcription Factors in Human Breast Cancer. PMID:35614183
Proteomic profiling of concurrently isolated primary microvascular endothelial cells, pericytes, and vascular smooth muscle cells from adult mouse heart. PMID:35614104
Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain. PMID:35614064
Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis. PMID:35613904
Prognostic implications of PPL expression in ovarian cancer. PMID:35612641
OTUB2 Promotes Proliferation and Migration of Hepatocellular Carcinoma Cells by PJA1 Deubiquitylation. PMID:35611163
The RNA-bound proteome of MRSA reveals post-transcriptional roles for helix-turn-helix DNA-binding and Rossmann-fold proteins. PMID:35610211
Serum proteome alterations during conventional and extracorporeal resuscitation in pigs. PMID:35606879
Fine mapping and candidate gene analysis of a dravet syndrome modifier locus on mouse chromosome 11. PMID:35606653
Computational Systems Biology of Morphogenesis. PMID:35604563
Japanese Encephalitis Virus NS4A Protein Interacts with PTEN-Induced Kinase 1 (PINK1) and Promotes Mitophagy in Infected Cells. PMID:35604158
A Case Study to Dissect Immunity to SARS-CoV-2 in a Neonate Nonhuman Primate Model. PMID:35603150
RNA-seq and Network Analysis Reveal Unique Chemokine Activity Signatures in the Synovial Tissue of Patients With Rheumatoid Arthritis. PMID:35602512
CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling. PMID:35601606
Sorghum root epigenetic landscape during limiting phosphorus conditions. PMID:35600998
Integrated Gut-Heart Axis and Network Pharmacology to Reveal the Mechanisms of the Huoxue Wentong Formula Against Myocardial Ischemia. PMID:35600966
Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration. PMID:35594347
Identification of PBK as a hub gene and potential therapeutic target for medulloblastoma. PMID:35593307
Cx43-mediated sorting of miRNAs into extracellular vesicles. PMID:35593040
Exploration of the System-Level Mechanisms of the Herbal Drug FDY003 for Pancreatic Cancer Treatment: A Network Pharmacological Investigation. PMID:35591866
The potential effects and mechanisms of hispidulin in the treatment of diabetic retinopathy based on network pharmacology. PMID:35590353
Connecting DCX, COMT and FMR1 in social behavior and cognitive impairment. PMID:35590332
Deep Visual Proteomics defines single-cell identity and heterogeneity. PMID:35590073
Differential gene expression and hallmarks of stemness in epithelial cells of the developing rat epididymis. PMID:35590013
RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer. PMID:35589755
Multi-omics approaches for comprehensive analysis and understanding of the immune response in the miniature pig breed. PMID:35587479
FAM198B promotes colorectal cancer progression by regulating the polarization of tumor-associated macrophages via the SMAD2 signaling pathway. PMID:35587159
In-depth proteomics characterization of ∆Np73 effectors identifies key proteins with diagnostic potential implicated in lymphangiogenesis, vasculogenesis and metastasis in colorectal cancer. PMID:35586989
Berberine Alleviates Gastroesophageal Reflux-Induced Airway Hyperresponsiveness in a Transient Receptor Potential A1-Dependent Manner. PMID:35586690
Clinical Evidence and Potential Mechanisms of Complementary Treatment of Ling Gui Zhu Gan Formula for the Management of Serum Lipids and Obesity. PMID:35586687
Genomics and Pathways Involved in Maize Resistance to Fusarium Ear Rot and Kernel Contamination With Fumonisins. PMID:35586219
A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations. PMID:35584218
Machine learning approach informs biology of cancer drug response. PMID:35581546
GenePlexus: a web-server for gene discovery using network-based machine learning. PMID:35580053
Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy. PMID:35579905
Molecular mechanism of ovarian toxicity of Hook.F. a study based on network pharmacology and molecular docking. PMID:35576115
Contribution of the Immune Response in the Ileum to the Development of Diarrhoea caused by Helminth Infection: Studies with the Sheep Model. PMID:35576023
Integrated Analysis of Transcriptome Data Revealed AURKA and KIF20A as Critical Genes in Medulloblastoma Progression. PMID:35574421
METTL3 Is Associated With the Malignancy of Esophageal Squamous Cell Carcinoma and Serves as a Potential Immunotherapy Biomarker. PMID:35574315
Comprehensive Genome-Wide Identification, Characterization, and Expression Analysis of CCHC-Type Zinc Finger Gene Family in Wheat (Triticum aestivum L.). PMID:35574096
Genome-wide Characterization of the JmjC Domain-Containing Histone Demethylase Gene Family Reveals GhJMJ24 and GhJMJ49 Involving in Somatic Embryogenesis Process in Cotton. PMID:35573733
Interaction of Neurovascular Signals in the Degraded Condylar Cartilage. PMID:35573252
Mapping and Validation of scRNA-Seq-Derived Cell-Cell Communication Networks in the Tumor Microenvironment. PMID:35572582
Early Post-Vaccination Gene Signatures Correlate With the Magnitude and Function of Vaccine-Induced HIV Envelope-Specific Plasma Antibodies in Infant Rhesus Macaques. PMID:35572573
Identification of genes and pathways leading to poor prognosis of non-small cell lung cancer using integrated bioinformatics analysis. PMID:35571642
Adipose-Derived Stem Cells Exosomes Improve Fat Graft Survival by Promoting Prolipogenetic Abilities through Wnt/β-Catenin Pathway. PMID:35571532
Exploring Key Genes to Construct a Diagnosis Model of Dilated Cardiomyopathy. PMID:35571180
BioTAGME: A Comprehensive Platform for Biological Knowledge Network Analysis. PMID:35571058
High Expression of DC-STAMP Gene Predicts Adverse Outcomes in AML. PMID:35571050
Identification of microRNA-mRNA regulatory network associated with oxidative DNA damage in human astrocytes. PMID:35570825
Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line. PMID:35568821
Prognostic and Immunotherapeutic Roles of KRAS in Pan-Cancer. PMID:35563733
Short-Term Blockade of Pro-Inflammatory Alarmin S100A9 Favorably Modulates Left Ventricle Proteome and Related Signaling Pathways Involved in Post-Myocardial Infarction Recovery. PMID:35563680
Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue. PMID:35563647
Biofluid Specificity of Long Non-Coding RNA Profile in Hypertension: Relevance of Exosomal Fraction. PMID:35563588
Identification of a Major QTL and Validation of Related Genes for Tiller Angle in Rice Based on QTL Analysis. PMID:35563584
Non-Cytokine Protein Profile of the Mesenchymal Stem Cell Secretome That Regulates the Androgen Production Pathway. PMID:35563028
Identification of TALE Transcription Factor Family and Expression Patterns Related to Fruit Chloroplast Development in Tomato (Solanum lycopersicum L.). PMID:35562896
Differential expression analysis of genes and long non-coding RNAs associated with KRAS mutation in colorectal cancer cells. PMID:35562390
Accurate, high-coverage assignment of in vivo protein kinases to phosphosites from in vitro phosphoproteomic specificity data. PMID:35560139
Comprehensive Analysis of N6-Methyladenosine Regulators in the Subcluster Classification and Drug Candidates Prediction of Severe Obstructive Sleep Apnea. PMID:35559050
The Regulatory Network and Role of the circRNA-miRNA-mRNA ceRNA Network in the Progression and the Immune Response of Wilms Tumor Based on RNA-Seq. PMID:35559038
Assessment of the prognostic value of SPOCK1 in clear cell renal cell carcinoma: a bioinformatics analysis. PMID:35558273
Peptide of Trichinella spiralis Infective Larval Extract That Harnesses Growth of Human Hepatoma Cells. PMID:35558100
Identification of the key genes controlling stomach adenocarcinoma stem cell characteristics via an analysis of stemness indices. PMID:35557559
A hominoid-specific endogenous retrovirus may have rewired the gene regulatory network shared between primordial germ cells and naïve pluripotent cells. PMID:35551519
Transcriptomic Profiling Revealed Lnc-GOLGA6A-1 as a Novel Prognostic Biomarker of Meningioma Recurrence. PMID:35551164
The Immunometabolic Atlas: A tool for design and interpretation of metabolomics studies in immunology. PMID:35550647
The distribution and function of GDE2, a regulator of spinal motor neuron survival, are disrupted in Amyotrophic Lateral Sclerosis. PMID:35550203
Network Pharmacology Analysis of Hewei Jiangni Granule for Gastroesophageal Reflux Disease and Experimental Verification of Its Anti-Neurogenic Inflammation Mechanism. PMID:35547866
HOXA10 Regulates the Synthesis of Cholesterol in Endometrial Stromal Cells. PMID:35546998
Functional genome-wide short hairpin RNA library screening identifies key molecules for extracellular vesicle secretion from microglia. PMID:35545052
One-Pot Exosome Proteomics Enabled by a Photocleavable Surfactant. PMID:35543580
Andrographolide in atherosclerosis: integrating network pharmacology and in vitro pharmacological evaluation. PMID:35543243
Apex Predator Nematodes and Meso-Predator Bacteria Consume Their Basal Insect Prey through Discrete Stages of Chemical Transformations. PMID:35543104
SNAIL Induces EMT and Lung Metastasis of Tumours Secreting CXCL2 to Promote the Invasion of M2-Type Immunosuppressed Macrophages in Colorectal Cancer. PMID:35541899
Sparganin A alleviates blood stasis syndrome and its key targets by molecular docking. PMID:35541782
Artificial intelligence in cancer target identification and drug discovery. PMID:35538061
Open Search-Based Proteomics Reveals Widespread Tryptophan Modifications Associated with Hypoxia in Lung Cancer. PMID:35535361
Gene Expression Profiling of the Habenula in Rats Exposed to Chronic Restraint Stress. PMID:35534192
Serine Protease Inhibitors Restrict Host Susceptibility to SARS-CoV-2 Infections. PMID:35532162
Network Pharmacology with Experimental Investigation of the Mechanisms of Rhizoma Polygonati against Prostate Cancer with Additional Herbzymatic Activity. PMID:35531567
Identification of immune-related biomarkers associated with tumorigenesis and prognosis in skin cutaneous melanoma. PMID:35530289
Identification of Bioactive Components of Stephania epigaea Lo and Their Potential Therapeutic Targets by UPLC-MS/MS and Network Pharmacology. PMID:35529936
A Tau Pathogenesis-Based Network Pharmacology Approach for Exploring the Protections of Chuanxiong Rhizoma in Alzheimer's Disease. PMID:35529440
[METTL27 is a prognostic biomarker of colon cancer and associated with immune invasion]. PMID:35527484
Small RNA sequencing and bioinformatics analysis of RAW264.7-derived exosomes after Mycobacterium Bovis Bacillus Calmette-Guérin infection. PMID:35525953
Construction of lncRNA-miRNA-mRNA network based on ceRNA mechanism reveals the function of lncRNA in the pathogenesis of gout. PMID:35524416
RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness. PMID:35521527
Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas. PMID:35519826
Peduncle Necking in Rosa hybrida Induces Stress-Related Transcription Factors, Upregulates Galactose Metabolism, and Downregulates Phenylpropanoid Biosynthesis Genes. PMID:35519800
EpCAM as a Novel Biomarker for Survivals in Prostate Cancer Patients. PMID:35517503
Prediction and Inferred Evolution of Acid Tolerance Genes in the Biotechnologically Important Acidihalobacter Genus. PMID:35516430
Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0. PMID:35516420
A combination of metabolite profiling and network pharmacology to explore the potential pharmacological changes of secoisolariciresinol-diglycoside. PMID:35514403
Construction and validation of a prognostic model of RNA binding proteins in clear cell renal carcinoma. PMID:35513791
Application of two-dimensional difference gel electrophoresis to identify protein changes between center, margin, and adjacent non-tumor tissues obtained from non-small-cell lung cancer with adenocarcinoma or squamous cell carcinoma subtype. PMID:35512017
Bioinformatic Analyzes of the Association Between Upregulated Expression of JUN Gene via APOBEC-Induced FLG Gene Mutation and Prognosis of Cervical Cancer. PMID:35510248
Mechanism of Ba Zhen Tang Delaying Skin Photoaging Based on Network Pharmacology and Molecular Docking. PMID:35510223
scTenifoldKnk: An efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation. PMID:35510185
Systematic Analysis of Chemokines Reveals CCL18 is a Prognostic Biomarker in Glioblastoma. PMID:35509325
P. aeruginosa type III and type VI secretion systems modulate early response gene expression in type II pneumocytes in vitro. PMID:35508983
Systematic identification of ALK substrates by integrated phosphoproteome and interactome analysis. PMID:35508387
IMEx Databases: Displaying Molecular Interactions into a Single, Standards-Compliant Dataset. PMID:35507258
Biological networks in gestational diabetes mellitus: insights into the mechanism of crosstalk between long non-coding RNA and N6-methyladenine modification. PMID:35505296
Exploring YAP1-centered networks linking dysfunctional CFTR to epithelial-mesenchymal transition. PMID:35500936
Selective bromodomain and extra-terminal bromodomain inhibitor inactivates macrophages and hepatic stellate cells to inhibit liver inflammation and fibrosis. PMID:35499161
Walnut N-Acetylserotonin Methyltransferase Gene Family Genome-Wide Identification and Diverse Functions Characterization During Flower Bud Development. PMID:35498672
Construction and Validation of Angiogenesis-Related Prognostic Risk Signature to Facilitate Survival Prediction and Biomarker Excavation of Breast Cancer Patients. PMID:35498539
Pancreas Whole Tissue Transcriptomics Highlights the Role of the Exocrine Pancreas in Patients With Recently Diagnosed Type 1 Diabetes. PMID:35498413
Identification of HMOX1 as a Critical Ferroptosis-Related Gene in Atherosclerosis. PMID:35498043
Systematic Elaboration of the Pharmacological Targets and Potential Mechanisms of ZhiKe GanCao Decoction for Preventing and Delaying Intervertebral Disc Degeneration. PMID:35497916
The Nutritional Properties, Chemical Compositions, and Functional Characteristics of the Aerial Parts of Adonis coerulea. PMID:35495930
The TbD1 Locus Mediates a Hypoxia-Induced Copper Response in Mycobacterium bovis. PMID:35495699
Identifying novel SMYD3 interactors on the trail of cancer hallmarks. PMID:35495117
Deciphering the potential anti-COVID-19 active ingredients in Andrographis paniculata (Burm. F.) Nees by combination of network pharmacology, molecular docking, and molecular dynamics. PMID:35494378
Discovery of Novel Drug Candidates for Alzheimer's Disease by Molecular Network Modeling. PMID:35493947
Genome-Wide Association Study Identifies New Risk Loci for Progression of Schistosomiasis Among the Chinese Population. PMID:35493725
An integrated network representation of multiple cancer-specific data for graph-based machine learning. PMID:35487924
Identification of invasion-metastasis associated MiRNAs in gallbladder cancer by bioinformatics and experimental validation. PMID:35484565
Identifying pleiotropic variants and candidate genes for fertility and reproduction traits in Holstein cattle via association studies based on imputed whole-genome sequence genotypes. PMID:35484513
Identification and validation of prognosis-associated DNA repair gene signatures in colorectal cancer. PMID:35484177
Functional network analysis of p85 and PI3K as potential gene targets and mechanism of oleanolic acid in overcoming breast cancer resistance to tamoxifen. PMID:35482141
Listeria monocytogenes exposed to antimicrobial peptides displays differential regulation of lipids and proteins associated to stress response. PMID:35482131
Membranome 3.0: Database of single-pass membrane proteins with AlphaFold models. PMID:35481632
Overexpression of SSR2 promotes proliferation of liver cancer cells and predicts prognosis of patients with hepatocellular carcinoma. PMID:35481617
Transcriptome and Proteome Analysis in LUHMES Cells Overexpressing Alpha-Synuclein. PMID:35481270
Metabolome profiling and molecular docking analysis revealed the metabolic differences and potential pharmacological mechanisms of the inflorescence and succulent stem of Cistanche deserticola. PMID:35480642
m6A Regulator-Mediated RNA Methylation Modification Patterns are Involved in the Pathogenesis and Immune Microenvironment of Depression. PMID:35480327
Cyclin-Dependent Kinase 6 Identified as the Target Protein in the Antitumor Activity of Tetrastigma hemsleyanum. PMID:35480115
Mechanism of Jujube (Ziziphus jujuba Mill.) Fruit in the Appetite Regulation Based on Network Pharmacology and Molecular Docking Method. PMID:35480085
Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis. PMID:35480028
Activation of Complement Pathways in Kidney Tissue May Mediate Tubulointerstitial Injury in Diabetic Nephropathy. PMID:35479942
CD19 and POU2AF1 are Potential Immune-Related Biomarkers Involved in the Emphysema of COPD: On Multiple Microarray Analysis. PMID:35479834
Icariin: A Potential Molecule for Treatment of Knee Osteoarthritis. PMID:35479319
Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways. PMID:35479305
In Silico Identification and Characterization of a Hypothetical Protein From Rhodobacter capsulatus Revealing S-Adenosylmethionine-Dependent Methyltransferase Activity. PMID:35478993
Proteome-wide identification of palmitoylated proteins in mouse testis. PMID:35477839
High expression of RIPK2 is associated with Taxol resistance in serous ovarian cancer. PMID:35477477
The identification of liver metastasis- and prognosis-associated genes in pancreatic ductal adenocarcinoma. PMID:35477379
The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses. PMID:35475759
Putative functions of EpsK in teichuronic acid synthesis and phosphate starvation in Bacillus licheniformis. PMID:35475252
Motif-centric phosphoproteomics to target kinase-mediated signaling pathways. PMID:35474870
Differences Between Sorafenib and Lenvatinib Treatment from Genetic and Clinical Perspectives for Patients with Hepatocellular Carcinoma. PMID:35473892
The potential mechanism of Fructus Ligustri Lucidi promoting osteogenetic differentiation of bone marrow mesenchymal stem cells based on network pharmacology, molecular docking and experimental identification. PMID:35473508
Single-cell RNA-Seq of human esophageal epithelium in homeostasis and allergic inflammation. PMID:35472002
Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2. PMID:35469023
Glycation modulates glutamatergic signaling and exacerbates Parkinson's disease-like phenotypes. PMID:35468899
Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors. PMID:35467532
Monitoring of inflammation using novel biosensor mouse model reveals tissue- and sex-specific responses to Western diet. PMID:35466363
Development an Immune-Related MicroRNA Risk Index in Hepatocellular Carcinoma. PMID:35466321
Potential Candidates for Biomarkers in Bipolar Disorder: A Proteomic Approach through Systems Biology. PMID:35466093
Deciphering Molecular Mechanism Underlying Self-Flocculation of Zymomonas mobilis for Robust Production. PMID:35465724
The Dysregulation of SOX Family Correlates with DNA Methylation and Immune Microenvironment Characteristics to Predict Prognosis in Hepatocellular Carcinoma. PMID:35465267
Integrated Bioinformatics Analysis Identifies a New Stemness Index-Related Survival Model for Prognostic Prediction in Lung Adenocarcinoma. PMID:35464867
Bioinformatics and System Biology Approach to Identify the Influences of COVID-19 on Rheumatoid Arthritis. PMID:35464423
Development and Validation of Novel Prognostic Models for Immune-Related Genes in Osteosarcoma. PMID:35463956
Integrated Bioinformatics-Based Analysis of Hub Genes and the Mechanism of Immune Infiltration Associated With Acute Myocardial Infarction. PMID:35463752
Integrated Bioinformatics Analysis and Verification of Gene Targets for Myocardial Ischemia-Reperfusion Injury. PMID:35463067
Genome-wide identification, characterization of expansin gene family of banana and their expression pattern under various stresses. PMID:35463044
PtncRNAdb: plant transfer RNA-derived non-coding RNAs (tncRNAs) database. PMID:35462956
Proprietary Medicines Containing Bupleurum chinense DC. (Chaihu) for Depression: Network Meta-Analysis and Network Pharmacology Prediction. PMID:35462897
RNA Editing-Associated Post-Transcriptional Gene Regulation in Rheumatoid Arthritis. PMID:35462874
Genome-wide identification, molecular characterization, and gene expression analyses of honeysuckle NHX antiporters suggest their involvement in salt stress adaptation. PMID:35462769
Association of heat shock protein 8 with atopic march in a murine experimental model. PMID:35462760
Carry-over effects of dry period heat stress on the mammary gland proteome and phosphoproteome in the subsequent lactation of dairy cows. PMID:35459770
Plasma Proteomic Profile of Patients with Tick-Borne Encephalitis and Co-Infections. PMID:35457192
Identification and Characterization of the MIKC-Type MADS-Box Gene Family in Brassica napus and Its Role in Floral Transition. PMID:35457106
Molecular Traits and Functional Exploration of BES1 Gene Family in Plants. PMID:35457060
Radiation-Induced Bystander Effect Mediated by Exosomes Involves the Replication Stress in Recipient Cells. PMID:35456987
Molecular Evolutionary Rate Predicts Intraspecific Genetic Polymorphism and Species-Specific Selection. PMID:35456514
Identification and Characterization of SOG1 (Suppressor of Gamma Response 1) Homologues in Plants Using Data Mining Resources and Gene Expression Profiling. PMID:35456473
Proteomics and Metabolomics Profiling of Platelets and Plasma Mediators of Thrombo-Inflammation in Gestational Hypertension and Preeclampsia. PMID:35455936
Integrated In Silico Analyses Identify PUF60 and SF3A3 as New Spliceosome-Related Breast Cancer RNA-Binding Proteins. PMID:35453681
Mycobacterium tuberculosis Affects Protein and Lipid Content of Circulating Exosomes in Infected Patients Depending on Tuberculosis Disease State. PMID:35453532
Transcriptomic Analysis of E. coli after Exposure to a Sublethal Concentration of Hydrogen Peroxide Revealed a Coordinated Up-Regulation of the Cysteine Biosynthesis Pathway. PMID:35453340
Modular and mechanistic changes across stages of colorectal cancer. PMID:35448980
Blood miRNAs Are Linked to Frequent Asthma Exacerbations in Childhood Asthma and Adult COPD. PMID:35447890
Plasma Proteomic Analysis Distinguishes Severity Outcomes of Human Ebola Virus Disease. PMID:35446128
Bioinformatic Analysis of the Effect of Silver Nanoparticles on Colorectal Cancer Cell Line. PMID:35445138
Identification of Immune-Related Key Genes as Potential Diagnostic Biomarkers of Sepsis in Children. PMID:35444449
Multi-omics integration and interactomics reveals molecular networks and regulators of the beneficial effect of yoga and exercise. PMID:35444372
ELOVL2-AS1 inhibits migration of triple negative breast cancer. PMID:35441059
Epigenetic drug screening defines a PRMT5 inhibitor-sensitive pancreatic cancer subtype. PMID:35439169
Hyper-Methylated Hub Genes of T-Cell Receptor Signaling Predict a Poor Clinical Outcome in Lung Adenocarcinoma. PMID:35432532
Identifying Key Biomarkers and Immune Infiltration in Female Patients with Ischemic Stroke Based on Weighted Gene Co-Expression Network Analysis. PMID:35432523
Identification and Verification of Potential Hub Genes in Amphetamine-Type Stimulant (ATS) and Opioid Dependence by Bioinformatic Analysis. PMID:35432486
miR-144-3p Is a Biomarker Related to Severe Corticosteroid-Dependent Asthma. PMID:35432357
Network Pharmacological Study on Mechanism of the Therapeutic Effect of Modified Duhuo Jisheng Decoction in Osteoporosis. PMID:35432213
Identification of Novel Key Molecular Signatures in the Pathogenesis of Experimental Diabetic Kidney Disease. PMID:35432190
NUSAP1 Could be a Potential Target for Preventing NAFLD Progression to Liver Cancer. PMID:35431924
MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis. PMID:35430453
Identification of Novel Genes and Associated Drugs in Cervical Cancer by Bioinformatics Methods. PMID:35428744
DualGCN: a dual graph convolutional network model to predict cancer drug response. PMID:35428192
LPInsider: a webserver for lncRNA-protein interaction extraction from the literature. PMID:35428172
Classification of human chronic inflammatory skin disease based on single-cell immune profiling. PMID:35427179
Systematic Characterization of the Clinical Relevance of KPNA4 in Pancreatic Ductal Adenocarcinoma. PMID:35425701
SOX18-associated gene signature predicts sepsis outcome. PMID:35422958
Construction and Bioinformatics Analysis of circRNA-miRNA-mRNA Network in Acute Myocardial Infarction. PMID:35422846
Bioinformatics Analysis Identified the Hub Genes, mRNA-miRNA-lncRNA Axis, and Signaling Pathways Involved in Rheumatoid Arthritis Pathogenesis. PMID:35422654
Hidden information on protein function in censuses of proteome foldedness. PMID:35422070
Research and experimental verification of the molecular mechanism of berberine in improving premature ovarian failure based on network pharmacology. PMID:35420511
Microarray screening reveals two non-conventional SUMO-binding modules linked to DNA repair by non-homologous end-joining. PMID:35420136
The Potential Role of Genomic Signature in Stage II Relapsed Colorectal Cancer (CRC) Patients: A Mono-Institutional Study. PMID:35418781
Cancer Relevance of Human Genes. PMID:35417011
Flap endonuclease 1 and DNA-PKcs synergistically participate in stabilizing replication fork to encounter replication stress in glioma cells. PMID:35414100
Uncovering the potential mechanism of Xue Fu Zhu Yu Decoction in the treatment of intracerebral hemorrhage. PMID:35413898
Whole blood transcriptome profiling identifies candidate genes associated with alopecia in male giant pandas (Ailuropoda melanoleuca). PMID:35413801
Single-cell RNA sequencing coupled to TCR profiling of large granular lymphocyte leukemia T cells. PMID:35411048
Molecular mechanism by which CDCP1 promotes proneural-mesenchymal transformation in primary glioblastoma. PMID:35410293
Applying Protein-Protein Interactions and Complex Networks to Identify Novel Genes in Retinitis Pigmentosa Pathogenesis. PMID:35409321
A Single Bout of Ultra-Endurance Exercise Reveals Early Signs of Muscle Aging in Master Athletes. PMID:35409073
Proteomic Analysis of Methylglyoxal Modifications Reveals Susceptibility of Glycolytic Enzymes to Dicarbonyl Stress. PMID:35409048
Environmental Phenol and Paraben Exposure Risks and Their Potential Influence on the Gene Expression Involved in the Prognosis of Prostate Cancer. PMID:35409038
Systematic Analysis and Expression Profiles of the 4-Coumarate: CoA Ligase (4CL) Gene Family in Pomegranate (Punica granatum L.). PMID:35408870
Functional Protein Composition in Femoral Glands of Sand Lizards (Lacerta agilis). PMID:35408771
The Anti-Constipation Effects of Raffino-Oligosaccharide on Gut Function in Mice Using Neurotransmitter Analyses, 16S rRNA Sequencing and Targeted Screening. PMID:35408632
Redox and Hormonal Changes in the Transcriptome of Grape (Vitis vinifera) Berries during Natural Noble Rot Development. PMID:35406844
RNA Editing in Glioma as a Sexually Dimorphic Prognostic Factor That Affects mRNA Abundance in Fatty Acid Metabolism and Inflammation Pathways. PMID:35406793
Construction of disease-specific cytokine profiles by associating disease genes with immune responses. PMID:35404985
Unbiased proteomics, histochemistry, and mitochondrial DNA copy number reveal better mitochondrial health in muscle of high-functioning octogenarians. PMID:35404238
Proteomic-Based Machine Learning Analysis Reveals PYGB as a Novel Immunohistochemical Biomarker to Distinguish Inverted Urothelial Papilloma From Low-Grade Papillary Urothelial Carcinoma With Inverted Growth. PMID:35402263
Cellular Interaction Analysis Characterizing Immunosuppressive Microenvironment Functions in MM Tumorigenesis From Precursor Stages. PMID:35401705
Comprehensive Analysis of YTHDF1 Immune Infiltrates and ceRNA in Human Esophageal Carcinoma. PMID:35401696
Genome-Wide Identification and Expression Analysis of the Thioredoxin (Trx) Gene Family Reveals Its Role in Leaf Rust Resistance in Wheat (Triticum aestivum L.). PMID:35401694
An Autoantigen Atlas From Human Lung HFL1 Cells Offers Clues to Neurological and Diverse Autoimmune Manifestations of COVID-19. PMID:35401574
Genomic Evidence Supports the Recognition of Endometriosis as an Inflammatory Systemic Disease and Reveals Disease-Specific Therapeutic Potentials of Targeting Neutrophil Degranulation. PMID:35401535
Utilising Network Pharmacology to Explore Underlying Mechanism of Astragalus membranaceus in Improving Sepsis-Induced Inflammatory Response by Regulating the Balance of IκBα and NF-κB in Rats. PMID:35399630
Jasmonates and Histone deacetylase 6 activate Arabidopsis genome-wide histone acetylation and methylation during the early acute stress response. PMID:35399062
Hypothetical protein predicted to be tumor suppressor: a protein functional analysis. PMID:35399005
miR-211-3p enhances induction chemotherapy insensitivity by upregulating CSF2/CCL20/TNF signaling in hypopharyngeal squamous cell carcinoma. PMID:35397087
Novel integrated workflow allows production and in-depth quality assessment of multifactorial reprogrammed skeletal muscle cells from human stem cells. PMID:35396689
The tobacco phosphatidylethanolamine-binding protein NtFT4 increases the lifespan of Drosophila melanogaster by interacting with the proteostasis network. PMID:35396341
Pan-cancer analysis on the role of PIK3R1 and PIK3R2 in human tumors. PMID:35395865
Single-Cell Transcriptome Analysis Reveals the Role of Pancreatic Secretome in COVID-19 Associated Multi-organ Dysfunctions. PMID:35394619
Proteomic and Phosphoproteomic Changes of MAPK-Related Inflammatory Response in an Animal Model of Neuropathic Pain by Differential Target Multiplexed SCS and Low-Rate SCS. PMID:35392631
Marek's Disease Virus and Reticuloendotheliosis Virus Coinfection Enhances Viral Replication and Alters Cellular Protein Profiles. PMID:35392111
Exploring Active Compounds and Mechanisms of Angong Niuhuang Wan on Ischemic Stroke Based on Network Pharmacology and Molecular Docking. PMID:35388303
Network Pharmacology Integrated with Transcriptomics Deciphered the Potential Mechanism of Codonopsis pilosula against Hepatocellular Carcinoma. PMID:35388300
Corticolimbic DCC gene co-expression networks as predictors of impulsivity in children. PMID:35388180
eccDNAdb: a database of extrachromosomal circular DNA profiles in human cancers. PMID:35388171
Potential Therapeutic Targets of Rehmannia Formulations on Diabetic Nephropathy: A Comparative Network Pharmacology Analysis. PMID:35387335
Molecular Mechanism Underlying Effects of Wumeiwan on Steroid-Dependent Asthma: A Network Pharmacology, Molecular Docking, and Experimental Verification Study. PMID:35386850
In-Silico and In-Vitro Analysis of Human SOS1 Protein Causing Noonan Syndrome - A Novel Approach to Explore the Molecular Pathways. PMID:35386434
A systems biology study unveils the association between a melatonin biosynthesis gene, O-methyl transferase 1 (OMT1) and wheat (Triticum aestivum L.) combined drought and salinity stress tolerance. PMID:35386021
Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer. PMID:35385746
Genetic estimates of correlation and causality between blood-based biomarkers and psychiatric disorders. PMID:35385317
Tissue Specific Dual RNA-Seq Defines Host-Parasite Interplay in Murine Visceral Leishmaniasis Caused by Leishmania donovani and Leishmania infantum. PMID:35384718
Physical and functional interactome atlas of human receptor tyrosine kinases. PMID:35384245
Single-Cell Chromatin and Gene-Regulatory Dynamics of Mouse Nephron Progenitors. PMID:35383123
New insights into the genetic etiology of Alzheimer's disease and related dementias. PMID:35379992
Comprehensive Analysis of the Expression and Prognostic Significance of the CENP Family in Breast Cancer. PMID:35378917
Plasma proteome profiling combined with clinical and genetic features reveals the pathophysiological characteristics of β-thalassemia. PMID:35378860
Potential Molecular Mechanism of Yishen Capsule in the Treatment of Diabetic Nephropathy Based on Network Pharmacology and Molecular Docking. PMID:35378831
Proteomic Response Revealed Signaling Pathways Involving in the Mechanism of Polymyxin B-Induced Melanogenesis. PMID:35377227
Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques. PMID:35377064
Protein Network Analysis Reveals a Functional Connectivity of Dysregulated Processes in ALS and SMA. PMID:35372839
The Prognostic Significance and Gene Expression Characteristics of Gastric Signet-Ring Cell Carcinoma: A Study Based on the SEER and TCGA Databases. PMID:35372476
Development and Validation of Ischemic Events Related Signature After Carotid Endarterectomy. PMID:35372347
MD2 Is a Potential Biomarker Associated with Immune Cell Infiltration in Gliomas. PMID:35372062
Systematic Analysis of the Expression and Prognosis of Fcγ Receptors in Clear Cell Renal Cell Carcinoma. PMID:35372055
APOE Is a Prognostic Biomarker and Correlates with Immune Infiltrates in Papillary Thyroid Carcinoma. PMID:35371313
Cleavage Stimulation Factor Subunit 2: Function Across Cancers and Potential Target for Chemotherapeutic Drugs. PMID:35370655
Novel Zinc-Related Differentially Methylated Regions in Leukocytes of Women With and Without Obesity. PMID:35369101
Identification of Potential Diagnostic and Prognostic Biomarkers for Gastric Cancer Based on Bioinformatic Analysis. PMID:35368700
Ultrastructural and proteomic profiling of mitochondria-associated endoplasmic reticulum membranes reveal aging signatures in striated muscle. PMID:35368021
bZIP transcription factors PcYap1 and PcRsmA link oxidative stress response to secondary metabolism and development in Penicillium chrysogenum. PMID:35366869
Dissection of valine-glutamine genes and their responses to drought stress in Arachis hypogaea cv. Tifrunner. PMID:35366145
Molecular mechanisms of Huanglian jiedu decoction on ulcerative colitis based on network pharmacology and molecular docking. PMID:35365737
Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor. PMID:35365682
Current progress and open challenges for applying deep learning across the biosciences. PMID:35365602
A network biology approach to identify crucial host targets for COVID-19. PMID:35364279
Overexpression of the WOX5 gene inhibits shoot development. PMID:35362363
The D2R-DISC1 protein complex and associated proteins are altered in schizophrenia and normalized with antipsychotic treatment. PMID:35361701
A Multi-Omics Pan-Cancer Analysis of 4EBP1 in Cancer Prognosis and Cancer-Associated Fibroblasts Infiltration. PMID:35360872
The High Expression of Minichromosome Maintenance Complex Component 5 Is an Adverse Prognostic Factor in Lung Adenocarcinoma. PMID:35360518
Genome-Wide Identification, Evolution and Expression Analysis of the Glutathione S-Transferase Supergene Family in Euphorbiaceae. PMID:35360301
Network Pharmacology Identifies Therapeutic Targets and the Mechanisms of Glutathione Action in Ferroptosis Occurring in Oral Cancer. PMID:35359830
Comprehensive Analysis of the Differential Expression and Prognostic Value of Histone Deacetylases in Glioma. PMID:35359455
Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix Adenocarcinoma. PMID:35359411
Characterization of Soluble Cell-Free Coelomic Fluid Proteome from the Starfish Marthasterias glacialis. PMID:35359330
Integrative epigenomic and transcriptomic analyses reveal metabolic switching by intermittent fasting in brain. PMID:35357643
SNRPD1/E/F/G Serve as Potential Prognostic Biomarkers in Lung Adenocarcinoma. PMID:35356432
Application of Transcriptomics for Predicting Protein Interaction Networks, Drug Targets and Drug Candidates. PMID:35356062
The Shared Mechanism and Candidate Drugs of Multiple Sclerosis and Sjögren's Syndrome Analyzed by Bioinformatics Based on GWAS and Transcriptome Data. PMID:35356004
Antigen-Presenting B Cells Program the Efferent Lymph T Helper Cell Response. PMID:35355990
Yishen Qingli Heluo Granule in the Treatment of Chronic Kidney Disease: Network Pharmacology Analysis and Experimental Validation. PMID:35355655
DNA methylation signatures in human neonatal blood following maternal antenatal corticosteroid treatment. PMID:35354798
Genome-wide identification and analysis of prognostic features in human cancers. PMID:35354049
Labeling of heterochronic ribosomes reveals C1ORF109 and SPATA5 control a late step in human ribosome assembly. PMID:35354024
Inflammation and Brain Structure in Schizophrenia and Other Neuropsychiatric Disorders: A Mendelian Randomization Study. PMID:35353173
Coronavirus Host Genetics South Africa (COHG-SA) database-a variant database for gene regions associated with SARS-CoV-2 outcomes. PMID:35351987
Human forebrain organoids reveal connections between valproic acid exposure and autism risk. PMID:35351869
DAMPs/PAMPs induce monocytic TLR activation and tolerance in COVID-19 patients; nucleic acid binding scavengers can counteract such TLR agonists. PMID:35349874
Crystal structure and metal binding properties of the periplasmic iron component EfeM from Pseudomonas syringae EfeUOB/M iron-transport system. PMID:35348940
Diseases 2.0: a weekly updated database of disease-gene associations from text mining and data integration. PMID:35348648
Aryl-hydrocarbon receptor-interacting protein regulates tumorigenic and metastatic properties of colorectal cancer cells driving liver metastasis. PMID:35347323
Liver X receptor-agonist treatment rescues degeneration in a Drosophila model of hereditary spastic paraplegia. PMID:35346366
Microbial and molecular differences according to the location of head and neck cancers. PMID:35346218
Integrative analyses of biomarkers and pathways for heart failure. PMID:35346191
Integrated Analysis of Microarray Studies to Identify Novel Diagnostic Markers in Bladder Pain Syndrome/Interstitial Cystitis with Hunner Lesion. PMID:35342305
Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression. PMID:35340765
The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective. PMID:35338126
Targeting of Protein Kinase CK2 Elicits Antiviral Activity on Bovine Coronavirus Infection. PMID:35336959
Update of gene expression/methylation and MiRNA profiling in colorectal cancer; application in diagnosis, prognosis, and targeted therapy. PMID:35333898
Whole-genome sequencing and gene sharing network analysis powered by machine learning identifies antibiotic resistance sharing between animals, humans and environment in livestock farming. PMID:35333870
Overexpressing PLOD Family Genes Predict Poor Prognosis in Pancreatic Cancer. PMID:35330878
Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy. PMID:35330838
HSPB8 is a Potential Prognostic Biomarker that Correlates With Immune Cell Infiltration in Bladder Cancer. PMID:35330734
Identification of Potential Genes Encoding Protein Transporters in Arabidopsis thaliana Glucosinolate (GSL) Metabolism. PMID:35330077
Collagen Family and Other Matrix Remodeling Proteins Identified by Bioinformatics Analysis as Hub Genes Involved in Gastric Cancer Progression and Prognosis. PMID:35328635
Pediatric Brain Tumors: Signatures from the Intact Proteome. PMID:35328618
Tissue-Specific Methylation Biosignatures for Monitoring Diseases: An In Silico Approach. PMID:35328380
Tumor Heterogeneity and Molecular Characteristics of Glioblastoma Revealed by Single-Cell RNA-Seq Data Analysis. PMID:35327982
Network Theoretical Approach to Explore Factors Affecting Signal Propagation and Stability in Dementia's Protein-Protein Interaction Network. PMID:35327643
A Bioinformatics-Assisted Review on Iron Metabolism and Immune System to Identify Potential Biomarkers of Exercise Stress-Induced Immunosuppression. PMID:35327526
Fibrin, Bone Marrow Cells and Macrophages Interactively Modulate Cardiomyoblast Fate. PMID:35327330
Comprehensive Analyses of Bone and Cartilage Transcriptomes Evince Ion Transport, Inflammation and Cartilage Development-Related Genes Involved in Chickens' Femoral Head Separation. PMID:35327184
Polymyxin Induces Significant Transcriptomic Perturbations of Cellular Signalling Networks in Human Lung Epithelial Cells. PMID:35326770
In Silico Analysis of Ion Channels and Their Correlation with Epithelial to Mesenchymal Transition in Breast Cancer. PMID:35326596
The Matrisome Is Associated with Metabolic Reprograming in Stem-like Phenotypes of Gastric Cancer. PMID:35326589
Tandem Mass Tagging-Based Quantitative Proteomics Analysis Reveals Damage to the Liver and Brain of Hypophthalmichthys molitrix Exposed to Acute Hypoxia and Reoxygenation. PMID:35326239
Vitreous Humor Proteome: Targeting Oxidative Stress, Inflammation, and Neurodegeneration in Vitreoretinal Diseases. PMID:35326156
Analysis of the expression and prognosis for leukocyte immunoglobulin-like receptor subfamily B in human liver cancer. PMID:35321724
Identifying large-scale interaction atlases using probabilistic graphs and external knowledge. PMID:35321220
Defining mammary basal cell transcriptional states using single-cell RNA-sequencing. PMID:35318370
Using bioinformatics and systems biology to discover common pathogenetic processes between sarcoidosis and COVID-19. PMID:35317263
Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression. PMID:35317119
Insights into the Differential Preservation of Bone Proteomes in Inhumed and Entombed Cadavers from Italian Forensic Caseworks. PMID:35316604
Elevation of ADAM12 facilitates tumor progression by enhancing metastasis and immune infiltration in gastric cancer. PMID:35315496
Systematic analysis of the expression and prognostic value of ITPR1 and correlation with tumor infiltrating immune cells in breast cancer. PMID:35313846
Overexpression of CISD1 Predicts Worse Survival in Hepatocarcinoma Patients. PMID:35313629
Diagnostic Value, Prognostic Value, and Immune Infiltration of LOX Family Members in Liver Cancer: Bioinformatic Analysis. PMID:35311155
NcRNA-Mediated High Expression of HMMR as a Prognostic Biomarker Correlated With Cell Proliferation and Cell Migration in Lung Adenocarcinoma. PMID:35311097
New spinocerebellar ataxia subtype caused by SAMD9L mutation triggering mitochondrial dysregulation (SCA49). PMID:35310830
The Pan-Cancer Crosstalk Between the EFNA Family and Tumor Microenvironment for Prognosis and Immunotherapy of Gastric Cancer. PMID:35309935
Genome-wide Identification, Expression, and Functional Analysis of MdMSI Genes in Apples (Malus domestica Borkh.). PMID:35309144
Construction of a Pyroptosis-Related Signature for Prognostic Prediction and Characterization of Immune Microenvironment in Acute Myelogenous Leukemia. PMID:35308573
A Comparative Study of Systems Pharmacology and Gene Chip Technology for Predicting Targets of a Traditional Chinese Medicine Formula in Primary Liver Cancer Treatment. PMID:35308212
CDK Inhibition Reverses Acquired 5-Fluorouracil Resistance in Hepatocellular Carcinoma Cells. PMID:35308136
Understanding the activating mechanism of the immune system against COVID-19 by Traditional Indian Medicine: Network pharmacology approach. PMID:35305722
Identification of hub genes and transcription factors in patients with rheumatoid arthritis complicated with atherosclerosis. PMID:35304503
The colonic pathogen Entamoeba histolytica activates caspase-4/1 that cleaves the pore-forming protein gasdermin D to regulate IL-1β secretion. PMID:35303042
Antifungals influence the immune-related transcriptomic landscape of human monocytes after Aspergillus fumigatus infection. PMID:35301416
Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor. PMID:35301315
Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms. PMID:35301122
An Oxidative Stress-Related Genes Signature for Predicting Survival in Bladder Cancer: Based on TCGA Database and Bioinformatics. PMID:35300137
Identification of the Potential Key Genes and Pathways Involved in Lens Changes of High Myopia. PMID:35300133
Exploring the Mechanism of Yiqi Qingre Ziyin Method in Regulating Neuropeptide Expression for the Treatment of Atrophic Rhinitis. PMID:35299869
Identification of IL20RB as a Novel Prognostic and Therapeutic Biomarker in Clear Cell Renal Cell Carcinoma. PMID:35299868
Peripheral blood mononuclear cell gene expression and cytokine profiling in patients with intermittent claudication who exhibit exercise induced acute renal injury. PMID:35298547
Identifying causal genes for depression via integration of the proteome and transcriptome from brain and blood. PMID:35296807
Cancer cell-intrinsic resistance to BiTE therapy is mediated by loss of CD58 costimulation and modulation of the extrinsic apoptotic pathway. PMID:35296559
Identification of CXCL10 as a Prognostic Biomarker for Clear Cell Renal Cell Carcinoma. PMID:35296026
MCTS1 as a Novel Prognostic Biomarker and Its Correlation With Immune Infiltrates in Breast Cancer. PMID:35295953
Bioinformatics-Guided Analysis Uncovers AOX1 as an Osteogenic Differentiation-Relevant Gene of Human Mesenchymal Stem Cells. PMID:35295843
Exploring the Mechanism of Danshensu in the Treatment of Doxorubicin-Induced Cardiotoxicity Based on Network Pharmacology and Experimental Evaluation. PMID:35295262
BRCA1 mutations in high-grade serous ovarian cancer are associated with proteomic changes in DNA repair, splicing, transcription regulation and signaling. PMID:35292711
Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice. PMID:35290904
FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation. PMID:35290126
TCN1 is a potential prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma. PMID:35287670
Splice-disrupt genomic variants in prostate cancer. PMID:35286517
Integrated multi-omics analysis reveals miR-20a as a regulator for metabolic colorectal cancer. PMID:35284668
Comprehensive bioinformatics analysis of functional molecules in colorectal cancer. PMID:35284121
Identification of a glycolysis-related gene signature for predicting pancreatic cancer survival. PMID:35284107
DNA Methylation Markers and Prediction Model for Depression and Their Contribution for Breast Cancer Risk. PMID:35283726
LncRNA-miRNA-mRNA Network Analysis Reveals the Potential Biomarkers in Crohn's Disease Rats Treated with Herb-Partitioned Moxibustion. PMID:35282268
A transcriptomic analysis based on aberrant methylation levels revealed potential novel therapeutic targets for nasopharyngeal carcinoma. PMID:35282089
Comprehensive Transcriptome Analysis of Patients With Keratoconus Highlights the Regulation of Immune Responses and Inflammatory Processes. PMID:35281826
Streptococcus pneumoniae and Influenza A Virus Co-Infection Induces Altered Polyubiquitination in A549 Cells. PMID:35281454
Establishment of a 7-microRNA prognostic signature and identification of hub target genes in colorectal carcinoma. PMID:35281422
Analysis of prognostic and therapeutic values of drug resistance-related genes in the lung cancer microenvironment. PMID:35281414
Temporal regulation of alternative splicing events in rice memory under drought stress. PMID:35281128
Extracellular Vesicles From Kidney Allografts Express miR-218-5p and Alter Th17/Treg Ratios. PMID:35281056
Co-Expression and Combined Prognostic Value of CSPG4 and PDL1 in TP53-Aberrant Triple-Negative Breast Cancer. PMID:35280756
Based on the Network Pharmacology to Investigate the Mechanism of Qingjie Fuzheng Granules against Colorectal Cancer. PMID:35280511
Investigating the molecular mechanism of Compound Danshen Dropping Pills for the treatment of epilepsy by utilizing network pharmacology and molecular docking technology. PMID:35280369
Integrative Analyses of Genes Associated With Otologic Disorders in Turner Syndrome. PMID:35273637
Excessive replacement changes drive evolution of global sheep prion protein (PRNP) sequences. PMID:35273383
miR-378 affects metabolic disturbances in the mdx model of Duchenne muscular dystrophy. PMID:35273230
Causal association evaluation of diabetes with Alzheimer's disease and genetic analysis of antidiabetic drugs against Alzheimer's disease. PMID:35272707
mTOR activity is essential for retinal pigment epithelium regeneration in zebrafish. PMID:35271573
Genome-Wide Identification of Cotton (Gossypium spp.) Glycerol-3-Phosphate Dehydrogenase (GPDH) Family Members and the Role of GhGPDH5 in Response to Drought Stress. PMID:35270062
Deciphering the Host-Pathogen Interactome of the Wheat-Common Bunt System: A Step towards Enhanced Resilience in Next Generation Wheat. PMID:35269732
A Hybrid Machine Learning and Network Analysis Approach Reveals Two Parkinson's Disease Subtypes from 115 RNA-Seq Post-Mortem Brain Samples. PMID:35269707
Transcriptomic and Network Analyses Reveal Immune Modulation by Endocannabinoids in Approach/Avoidance Traits. PMID:35269678
Transcriptomics of Parental Care in the Hypothalamic-Septal Region of Female Zebra Finch Brain. PMID:35269661
Proximity Profiling of the CFTR Interaction Landscape in Response to Orkambi. PMID:35269585
G-Protein Coupled Receptor Dysregulation May Play Roles in Severe Preeclampsia-A Weighted Gene Correlation Network Analysis of Placental Gene Expression Profile. PMID:35269385
A Computational Text Mining-Guided Meta-Analysis Approach to Identify Potential Xerostomia Drug Targets. PMID:35268532
Paediatric Behçet's Disease: A Comprehensive Review with an Emphasis on Monogenic Mimics. PMID:35268369
PathwAX II: Network-based pathway analysis with interactive visualization of network crosstalk. PMID:35266519
Cerebrospinal fluid of progressive multiple sclerosis patients reduces differentiation and immune functions of oligodendrocyte progenitor cells. PMID:35266197
Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes. PMID:35264221
Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies-the role of HAS2, SHB and HBEGF. PMID:35264144
MUC20 as a novel prognostic biomarker in ccRCC correlating with tumor immune microenvironment modulation. PMID:35261796
Predisposition to atrioventricular septal defects may be caused by SOX7 variants that impair interaction with GATA4. PMID:35260939
A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease. PMID:35260714
Hematopoietic differentiation is characterized by a transient peak of entropy at a single-cell level. PMID:35260165
ETS-related gene (ERG) undermines genome stability in mouse prostate progenitors via Gsk3β dependent Nkx3.1 degradation. PMID:35259458
Biological mechanisms of aging predict age-related disease co-occurrence in patients. PMID:35259281
6-Hydroxydopamine Induces Neurodegeneration in Terminally Differentiated SH-SY5Y Neuroblastoma Cells via Enrichment of the Nucleosomal Degradation Pathway: a Global Proteomics Approach. PMID:35258800
Bioinformatic Analysis of Prognostic Value of Pyroptosis-Related Genes and Its Effect on Immune Cell Infiltration in Pancreatic Adenocarcinoma. PMID:35256857
Network pharmacology analysis reveals neuroprotection of Gynostemma pentaphyllum (Thunb.) Makino in Alzheimer' disease. PMID:35255879
Comprehensive analyses of prognostic biomarkers and immune infiltrates among histone lysine demethylases (KDMs) in hepatocellular carcinoma. PMID:35254477
LINC01094 Predicts Poor Prognosis in Patients With Gastric Cancer and is Correlated With EMT and Macrophage Infiltration. PMID:35254147
Association of SPI1 Haplotypes with Altered SPI1 Gene Expression and Alzheimer's Disease Risk. PMID:35253752
In-Depth Serum Proteomics by DIA-MS with In Silico Spectral Libraries Reveals Dynamics during the Active Phase of Systemic Juvenile Idiopathic Arthritis. PMID:35252692
Genes Involved in Maintaining Mitochondrial Membrane Potential Upon Electron Transport Chain Disruption. PMID:35252167
Uncover New Reactivity of Genetically Encoded Alkyl Bromide Non-Canonical Amino Acids. PMID:35252115
Inward Outward Signaling in Ovarian Cancer: Morpho-Phospho-Proteomic Profiling Upon Application of Hypoxia and Shear Stress Characterizes the Adaptive Plasticity of OVCAR-3 and SKOV-3 Cells. PMID:35251951
CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts. PMID:35251476
Quantitative Proteomics Analysis Expands the Roles of Lysine β-Hydroxybutyrylation Pathway in Response to Environmental β-Hydroxybutyrate. PMID:35251473
Molecular Mechanism Investigation on Monomer Kaempferol of the Traditional Medicine Dingqing Tablet in Promoting Apoptosis of Acute Myeloid Leukemia HL-60 Cells. PMID:35251215
Computational Systems Biology of Alfalfa - Bacterial Blight Host-Pathogen Interactions: Uncovering the Complex Molecular Networks for Developing Durable Disease Resistant Crop. PMID:35251063
SARS-CoV-2 Infection Triggers Phosphorylation: Potential Target for Anti-COVID-19 Therapeutics. PMID:35251015
Maternal Immune Activation and Interleukin 17A in the Pathogenesis of Autistic Spectrum Disorder and Why It Matters in the COVID-19 Era. PMID:35250672
Resveratrol Targets AKT1 to Inhibit Inflammasome Activation in Cardiomyocytes Under Acute Sympathetic Stress. PMID:35250567
Prognostic Significance and Therapeutic Target of CXC Chemokines in the Microenvironment of Lung Adenocarcinoma. PMID:35250303
Potential Role of the Chemotaxis System in Formation and Progression of Intracranial Aneurysms Through Weighted Gene Co-Expression Network Analysis. PMID:35250300
Transcriptional response of murine microglia in Alzheimer's disease and inflammation. PMID:35247975
Single-cell Characterization of the Cellular Landscape of Acral Melanoma Identifies Novel Targets for Immunotherapy. PMID:35247927
Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2. PMID:35246634
Stress vulnerability shapes disruption of motor cortical neuroplasticity. PMID:35246507
Abnormal expression and the significant prognostic value of aquaporins in clear cell renal cell carcinoma. PMID:35245343
The implication of holocytochrome c synthase mutation in Korean familial hypoplastic amelogenesis imperfecta. PMID:35243551
The Peptide-Drug Conjugate Melflufen Modulates the Unfolded Protein Response of Multiple Myeloma and Amyloidogenic Plasma Cells and Induces Cell Death. PMID:35243210
Network pharmacology analysis and experimental study strategy reveals the potential mechanism of puerarin against rotavirus. PMID:35242859
Integrative Genomics Sheds Light on Evolutionary Forces Shaping the Acidithiobacillia Class Acidophilic Lifestyle. PMID:35242113
High-content analysis of microRNAs involved in the phenotype regulation of vascular smooth muscle cells. PMID:35241704
Prognostic value and immune relevancy of a combined autophagy-, apoptosis- and necrosis-related gene signature in glioblastoma. PMID:35241019
In silico analysis highlighting the prevalence of BCL2L1 gene and its correlation to miRNA in human coronavirus (HCoV) genetic makeup. PMID:35240314
CTP sensing and Mec1ATR-Rad53CHK1/CHK2 mediate a two-layered response to inhibition of glutamine metabolism. PMID:35239666
Laser Capture Microdissection-Based mRNA Expression Microarrays and Single-Cell RNA Sequencing in Atherosclerosis Research. PMID:35237997
A master autoantigen-ome links alternative splicing, female predilection, and COVID-19 to autoimmune diseases. PMID:35237749
A New Prognostic Risk Score: Based on the Analysis of Autophagy-Related Genes and Renal Cell Carcinoma. PMID:35237298
Molecular hallmarks of heterochronic parabiosis at single-cell resolution. PMID:35236985
Gramicidin S and melittin: potential anti-viral therapeutic peptides to treat SARS-CoV-2 infection. PMID:35236909
Mechanistic basis of choline import involved in teichoic acids and lipopolysaccharide modification. PMID:35235350
Mass spectrometry and proteome analysis to identify SARS-CoV-2 protein from COVID-19 patient swab samples. PMID:35233542
DGAT2 Inhibition Potentiates Lipid Droplet Formation To Reduce Cytotoxicity in APOL1 Kidney Risk Variants. PMID:35232775
Identification of cell type specific ACE2 modifiers by CRISPR screening. PMID:35231079
Network Approaches for Precision Oncology. PMID:35230690
Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome. PMID:35230102
VPS29 Exerts Opposing Effects on Endocytic Viral Entry. PMID:35229640
Unheeded SARS-CoV-2 proteins? A deep look into negative-sense RNA. PMID:35229157
Pyroptosis-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with UCEC. PMID:35228898
Neuronal-glial communication perturbations in murine SOD1G93A spinal cord. PMID:35228715
Digital spatial profiling of collapsing glomerulopathy. PMID:35227689
Multi-omics evaluation of SARS-CoV-2 infected mouse lungs reveals dynamics of host responses. PMID:35224468
Predicting Diagnostic Gene Biomarkers Associated With Immune Checkpoints, N6-Methyladenosine, and Ferroptosis in Patients With Acute Myocardial Infarction. PMID:35224064
EGR1 and KLF4 as Diagnostic Markers for Abdominal Aortic Aneurysm and Associated With Immune Infiltration. PMID:35224035
Guanylate-Binding Protein 1 as a Potential Predictor of Immunotherapy: A Pan-Cancer Analysis. PMID:35222540
High Expression of PLAGL2 is Associated With Poor Prognosis in High-Grade Glioma. PMID:35222518
A DNA-Methylation-Driven Genes Based Prognostic Signature Reveals Immune Microenvironment in Pancreatic Cancer. PMID:35222383
Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis. PMID:35222279
SCNN1A Overexpression Correlates with Poor Prognosis and Immune Infiltrates in Ovarian Cancer. PMID:35221714
Olfactomedin-4 improves cutaneous wound healing by promoting skin cell proliferation and migration through POU5F1/OCT4 and ESR1 signalling cascades. PMID:35218417
Syndromic male subfertility: A network view of genome-phenome associations. PMID:35218153
Organoids from human tooth showing epithelial stemness phenotype and differentiation potential. PMID:35217915
Investigating Glioblastoma Multiforme Sub-Proteomes: A Computational Study of CUSA Fluid Proteomic Data. PMID:35216175
Uncovering a Hub Signaling Pathway of Antimicrobial-Antifungal-Anticancer Peptides' Axis on Short Cationic Peptides via Network Pharmacology Study. PMID:35216171
Exploring New Functional Aspects of HTLV-1 RNA-Binding Protein Rex: How Does Rex Control Viral Replication? PMID:35216000
Deciphering the Interactions of SARS-CoV-2 Proteins with Human Ion Channels Using Machine-Learning-Based Methods. PMID:35215201
Proteomic Profiling and In Silico Characterization of the Secretome of Anisakis simplex Sensu Stricto L3 Larvae. PMID:35215189
Identification of One Major QTL and a Novel Gene OsIAA17q5 Associated with Tiller Number in Rice Using QTL Analysis. PMID:35214873
Gene expression associated with human brain activations in facial expression recognition. PMID:35212890
A tRNA modifying enzyme as a tunable regulatory nexus for bacterial stress responses and virulence. PMID:35212379
Identification of a new RNA-binding proteins-based signature for prognostic prediction in gastric cancer. PMID:35212295
The Efficacy Mechanism of Epigallocatechin Gallate against Pre-Eclampsia based on Network Pharmacology and Molecular Docking. PMID:35211881
FOXM1/lncRNA TYMSOS/miR-214-3p-Mediated High Expression of NCAPG Correlates With Poor Prognosis and Cell Proliferation in Non-Small Cell Lung Carcinoma. PMID:35211508
Mutation of MUC16 Is Associated With Tumor Mutational Burden and Lymph Node Metastasis in Patients With Gastric Cancer. PMID:35211490
Identification of Hypoxia-Immune-Related Gene Signatures and Construction of a Prognostic Model in Kidney Renal Clear Cell Carcinoma. PMID:35211477
HDL-Associated Lipoproteins: Potential Prognostic Biomarkers for Gram-Negative Sepsis. PMID:35210815
Computational Drug Repurposing Based on a Recommendation System and Drug-Drug Functional Pathway Similarity. PMID:35209193
The Study of Microbe-Host Two-Way Communication. PMID:35208862
c-Met and EPHA7 Receptor Tyrosine Kinases Are Related to Prognosis in Clear Cell Renal Cell Carcinoma: Focusing on the Association with Myoferlin Expression. PMID:35205843
The Random Plots Graph Generation Model for Studying Systems with Unknown Connection Structures. PMID:35205591
The Role of VHL in the Development of von Hippel-Lindau Disease and Erythrocytosis. PMID:35205407
Methods to Improve Molecular Diagnosis in Genomic Cold Cases in Pediatric Neurology. PMID:35205378
Gene Ontology Groups and Signaling Pathways Regulating the Process of Avian Satellite Cell Differentiation. PMID:35205287
Identification of DPP4/CTNNB1/MET as a Theranostic Signature of Thyroid Cancer and Evaluation of the Therapeutic Potential of Sitagliptin. PMID:35205190
Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC. PMID:35204804
MiR-182-5p Modulates Prostate Cancer Aggressive Phenotypes by Targeting EMT Associated Pathways. PMID:35204688
Role of MBL2 Polymorphisms in Sepsis and Survival: A Pilot Study and In Silico Analysis. PMID:35204551
Identification of Potential Targets Linked to the Cardiovascular/Alzheimer's Axis through Bioinformatics Approaches. PMID:35203598
Cobalt Neurotoxicity: Transcriptional Effect of Elevated Cobalt Blood Levels in the Rodent Brain. PMID:35202246
Assessment of Zearalenone-Induced Cell Survival and of Global Gene Regulation in Mouse TM4 Sertoli Cells. PMID:35202126
Stx2 Induces Differential Gene Expression and Disturbs Circadian Rhythm Genes in the Proximal Tubule. PMID:35202097
Unraveling of interacting protein network of chaperonin TCP1 gamma subunit of Leishmania donovani. PMID:35199315
Effect of imputation on gene network reconstruction from single-cell RNA-seq data. PMID:35199064
p53-mediated neurodegeneration in the absence of the nuclear protein Akirin2. PMID:35198879
TMAO-Activated Hepatocyte-Derived Exosomes Are Widely Distributed in Mice with Different Patterns and Promote Vascular Inflammation. PMID:35198242
Ibrutinib reverses IL-6-induced osimertinib resistance through inhibition of Laminin α5/FAK signaling. PMID:35197546
MicroRNA miR-3646 promotes malignancy of lung adenocarcinoma cells by suppressing sorbin and SH3 domain-containing protein 1 via the c-Jun NH2-terminal kinase signaling pathway. PMID:35196185
Untargeted sequencing of circulating microRNAs in a healthy and diseased older population. PMID:35194110
Metaproteomic profiling of fungal gut colonization in gnotobiotic mice. PMID:35193703
Clinical implications and molecular mechanisms of Cyclin-dependent kinases 4 for patients with hepatocellular carcinoma. PMID:35193513
Genome-wide CRISPR/Cas9 screening identifies determinant of panobinostat sensitivity in acute lymphoblastic leukemia. PMID:35192680
Cultivating Lentinula edodes on Substrate Containing Composted Sawdust Affects the Expression of Carbohydrate and Aromatic Amino Acid Metabolism-Related Genes. PMID:35191774
S-Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S-Nitrosylation and Preeclampsia. PMID:35191317
MEFV and NLRP3 Inflammasome Expression Is Attributed to Immature Macrophages and Correlates with Serum Inflammatory Proteins in Crohn´s Disease Patients. PMID:35190924
Comprehensive Network Analysis Identified SIRT7, NTRK2, and CHI3L1 as New Potential Markers for Intervertebral Disc Degeneration. PMID:35190738
Proteome-defined changes in cellular pathways for decidua and trophoblast tissues associated with location and viability of early-stage pregnancy. PMID:35189928
A Comprehensive Prognostic Analysis of POLD1 in Hepatocellular Carcinoma. PMID:35189839
CENPF as an independent prognostic and metastasis biomarker corresponding to CD4+ memory T cells in cutaneous melanoma. PMID:35189004
Identification of Potential Biomarkers of Type 2 Diabetes Mellitus-Related Immune Infiltration Using Weighted Gene Coexpression Network Analysis. PMID:35187175
Synthesis and Antitumor Evaluation of Menthone-Derived Pyrimidine-Urea Compounds as Potential PI3K/Akt/mTOR Signaling Pathway Inhibitor. PMID:35186896
FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma. PMID:35186752
Characterization of Cell Cycle-Related Competing Endogenous RNAs Using Robust Rank Aggregation as Prognostic Biomarker in Lung Adenocarcinoma. PMID:35186743
Single-Cell Technologies to Decipher the Immune Microenvironment in Myeloid Neoplasms: Perspectives and Opportunities. PMID:35186713
A Calmodulin-Like Gene (GbCML7) for Fiber Strength and Yield Improvement Identified by Resequencing Core Accessions of a Pedigree in Gossypium barbadense. PMID:35185964
Immune Response Is Key to Genetic Mechanisms of SARS-CoV-2 Infection With Psychiatric Disorders Based on Differential Gene Expression Pattern Analysis. PMID:35185890
Identification of a novel four-gene diagnostic signature for patients with sepsis by integrating weighted gene co-expression network analysis and support vector machine algorithm. PMID:35184762
Transcription factor protein interactomes reveal genetic determinants in heart disease. PMID:35182466
DVPred: a disease-specific prediction tool for variant pathogenicity classification for hearing loss. PMID:35182233
New insights on familial colorectal cancer type X syndrome. PMID:35181726
Quantitative multiplexed proteomics analysis reveals reshaping of the lysine 2-hydroxyisobutyrylome in Fusarium graminearum by tebuconazole. PMID:35180840
Evaluating the detection ability of a range of epistasis detection methods on simulated data for pure and impure epistatic models. PMID:35180244
Anhydroicaritin Inhibits EMT in Breast Cancer by Enhancing GPX1 Expression: A Research Based on Sequencing Technologies and Bioinformatics Analysis. PMID:35178395
Identification of key genes and biological pathways in Chinese lung cancer population using bioinformatics analysis. PMID:35178291
Quantitative Proteomics Reveals the Role of Lysine 2-Hydroxyisobutyrylation Pathway Mediated by Tip60. PMID:35178156
Integrated Metabolomics and Network Pharmacology Revealed Hong-Hua-Xiao-Yao Tablet's Effect of Mediating Hormone Synthesis in the Treatment of Mammary Gland Hyperplasia. PMID:35177987
Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications. PMID:35177642
Evaluating the cytotoxicity and pathogenicity of multi-walled carbon nanotube through weighted gene co-expression network analysis: a nanotoxicogenomics study. PMID:35176998
Deciphering specific miRNAs in brain tumors: a 5-miRNA signature in glioblastoma. PMID:35175428
Characterization of the Cellular Microenvironment and Novel Specific Biomarkers in Pterygia Using RNA Sequencing. PMID:35174178
TMAO-Activated Hepatocyte-Derived Exosomes Impair Angiogenesis via Repressing CXCR4. PMID:35174166
Nucleolar and Coiled-Body Phosphoprotein 1 Is Associated With Stemness and Represents a Potential Therapeutic Target in Triple-Negative Breast Cancer. PMID:35174077
Deciphering the involvement of iron targets in colorectal cancer: a network biology approach. PMID:35173863
Prognostic Biomarker DDOST and Its Correlation With Immune Infiltrates in Hepatocellular Carcinoma. PMID:35173766
KeyPathwayMineR: De Novo Pathway Enrichment in the R Ecosystem. PMID:35173764
HJURP Promotes Malignant Progression and Mediates Sensitivity to Cisplatin and WEE1-inhibitor in Serous Ovarian Cancer. PMID:35173547
Identification Prognostic Value and Correlation with Tumor-Infiltrating Immune Cells of Tripartite-Motif Family Genes in Hepatocellular Carcinoma. PMID:35173473
Up regulated virulence genes in M. tuberculosis H37Rv gleaned from genome wide expression profiles. PMID:35173382
Elevated levels of serum CDCP1 in individuals recovering from severe COVID-19 disease. PMID:35172279
Transcriptional analysis of lung fibroblasts identifies PIM1 signaling as a driver of aging-associated persistent fibrosis. PMID:35167499
Notch-mediated Ephrin signaling disrupts islet architecture and β cell function. PMID:35167496
Using Surface Hydrophobicity Together with Empirical Potentials to Identify Protein-Protein Binding Sites: Application to the Interactions of E-cadherins. PMID:35167069
Negative Modulation of the Angiogenic Cascade Induced by Allosteric Kinesin Eg5 Inhibitors in a Gastric Adenocarcinoma In Vitro Model. PMID:35164221
Transcriptional Regulation of Yin-Yang 1 Expression through the Hypoxia Inducible Factor-1 in Pediatric Acute Lymphoblastic Leukemia. PMID:35163649
Transcriptomic Profile of Canine DH82 Macrophages Infected by Leishmania infantum Promastigotes with Different Virulence Behavior. PMID:35163386
Identification of a Novel Theranostic Signature of Metabolic and Immune-Inflammatory Dysregulation in Myocardial Infarction, and the Potential Therapeutic Properties of Ovatodiolide, a Diterpenoid Derivative. PMID:35163208
Mapping PP1c and Its Inhibitor 2 Interactomes Reveals Conserved and Specific Networks in Asexual and Sexual Stages of Plasmodium. PMID:35162991
De Novo Transcriptome of Mammillaria bombycina (Cactaceae) under In Vitro Conditions and Identification of Glyoxalase Genes. PMID:35161380
Voluntary Wheel Running in Old C57BL/6 Mice Reduces Age-Related Inflammation in the Colon but Not in the Brain. PMID:35159375
An Integrated In Silico, In Vitro and Tumor Tissues Study Identified Selenoprotein S (SELENOS) and Valosin-Containing Protein (VCP/p97) as Novel Potential Associated Prognostic Biomarkers in Triple Negative Breast Cancer. PMID:35158912
Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway. PMID:35156921
gpuZoo: Cost-effective estimation of gene regulatory networks using the Graphics Processing Unit. PMID:35156023
Study on the Active Constituents and Molecular Mechanism of Zhishi Xiebai Guizhi Decoction in the Treatment of CHD Based on UPLC-UESI-Q Exactive Focus, Gene Expression Profiling, Network Pharmacology, and Experimental Validation. PMID:35155889
Over-Expression and Prognostic Significance of FATP5, as a New Biomarker, in Colorectal Carcinoma. PMID:35155561
Downregulation of NAGLU in VEC Increases Abnormal Accumulation of Lysosomes and Represents a Predictive Biomarker in Early Atherosclerosis. PMID:35155448
Identification of Circular RNA-Based Immunomodulatory Networks in Colorectal Cancer. PMID:35155186
Predicting Radioresistant Biomarkers in Nasopharyngeal Carcinoma Patients Via Protein-Protein Interaction Network Analysis. PMID:35155161
Network Pharmacology Analysis on the Mechanism of Huangqi Sijunzi Decoction in Treating Cancer-Related Fatigue. PMID:35154614
The correlation and role analysis of SLC30A1 and SLC30A10 in cervical carcinoma. PMID:35154468
Herbal Formula Modified Bu-Shen-Huo-Xue Decoction Attenuates Intervertebral Disc Degeneration via Regulating Inflammation and Oxidative Stress. PMID:35154344
In Vivo and In Vitro Matured Oocytes From Mice of Advanced Reproductive Age Exhibit Alternative Splicing Processes for Mitochondrial Oxidative Phosphorylation. PMID:35154017
Alteration of EIF2 Signaling, Glycolysis, and Dopamine Secretion in Form-Deprived Myopia in Response to 1% Atropine Treatment: Evidence From Interactive iTRAQ-MS and SWATH-MS Proteomics Using a Guinea Pig Model. PMID:35153787
Identification of the Expression and Clinical Significance of E2F Family in Clear Cell Renal Cell Carcinoma. PMID:35153510
Novel Insights into the Stemness and Immune Privilege of Mesenchymal Stem Cells from Human Wharton Jelly by Single-Cell RNA Sequencing. PMID:35153292
Proteomic Profiles of Staphylococcus aureus Strains Associated with Subclinical Bovine Mastitis. PMID:35150342
In silico bioinformatics analysis for identification of differentially expressed genes and therapeutic drug molecules in Glucocorticoid-resistant Multiple myeloma. PMID:35150335
Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism. PMID:35150276
Machine learning prediction and tau-based screening identifies potential Alzheimer's disease genes relevant to immunity. PMID:35149761
Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease. PMID:35148841
Deceleration of the cell cycle underpins a switch from proliferative to terminal divisions in plant stomatal lineage. PMID:35148836
The molecular mechanism of Ligusticum wallichii for improving idiopathic pulmonary fibrosis: A network pharmacology and molecular docking study. PMID:35147109
Bioinformatic Approach to Unveil Key Differentially Expressed Proteins in Human Sperm After Slow and Rapid Cryopreservation. PMID:35145967
Arabidopsis Glutathione-S-Transferases GSTF11 and GSTU20 Function in Aliphatic Glucosinolate Biosynthesis. PMID:35145536
Identification of Shared Genes and Pathways in Periodontitis and Type 2 Diabetes by Bioinformatics Analysis. PMID:35145474
ILF2 enhances the DNA cytosine deaminase activity of tumor mutator APOBEC3B in multiple myeloma cells. PMID:35145187
Molecular basis of the association between transcription regulators nuclear respiratory factor 1 and inhibitor of DNA binding protein 3 and the development of microvascular lesions. PMID:35143811
Advancing drug safety science by integrating molecular knowledge with post-marketing adverse event reports. PMID:35143713
Second Heart Field-Derived Cells Contribute to Angiotensin II-Mediated Ascending Aortopathies. PMID:35143327
DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis. PMID:35143160
Further delineation of familial polycystic ovary syndrome (PCOS) via whole-exome sequencing: PCOS-related rare FBN3 and FN1 gene variants are identified. PMID:35141985
Construction and Comprehensive Analysis of a circRNA-miRNA-mRNA Regulatory Network to Reveal the Pathogenesis of Hepatocellular Carcinoma. PMID:35141281
Analyzing large scale gene expression data in colorectal cancer reveals important clues; CLCA1 and SELENBP1 downregulated in CRC not in normal and not in adenoma. PMID:35141024
Network Pharmacology and Molecular Docking Analysis on Pharmacological Mechanisms of Astragalus membranaceus in the Treatment of Gastric Ulcer. PMID:35140802
Network Pharmacology- and Molecular Docking-Based Identification of Potential Phytocompounds from Argyreia capitiformis in the Treatment of Inflammation. PMID:35140801
The Material Basis and Mechanism of Xuefu Zhuyu Decoction in Treating Stable Angina Pectoris and Unstable Angina Pectoris. PMID:35140797
LncRNA-miRNA-mRNA Networks of Gastrointestinal Cancers Representing Common and Specific LncRNAs and mRNAs. PMID:35140741
CX3CR1 Acts as a Protective Biomarker in the Tumor Microenvironment of Colorectal Cancer. PMID:35140706
The Multi-Omics Analysis of Key Genes Regulating EGFR-TKI Resistance, Immune Infiltration, SCLC Transformation in EGFR-Mutant NSCLC. PMID:35140497
SPINK5 is a Prognostic Biomarker Associated With the Progression and Prognosis of Laryngeal Squamous Cell Carcinoma Identified by Weighted Gene Co-Expression Network Analysis. PMID:35140453
Investigating the development of diarrhoea through gene expression analysis in sheep genetically resistant to gastrointestinal helminth infection. PMID:35140270
Human transcription factor protein interaction networks. PMID:35140242
Targeted proteomics improves cardiovascular risk prediction in secondary prevention. PMID:35139537
The atlas of ACE2 expression in fetal and adult human hearts reveals the potential mechanism of heart-injured patients infected with SARS-CoV-2. PMID:35138176
Prediction the Molecular Mechanism of Shengmai Injection in Acute Treatment of COVID-19 Based on Network Pharmacology. PMID:35136386
Molecular regulations of circadian rhythm and implications for physiology and diseases. PMID:35136018
Lactate Rewires Lipid Metabolism and Sustains a Metabolic-Epigenetic Axis in Prostate Cancer. PMID:35135811
Genomewide transcriptional response of Escherichia coli O157:H7 to norepinephrine. PMID:35135480
Protein phase separation hotspots at the presynapse. PMID:35135293
Interpretable network-guided epistasis detection. PMID:35134928
The mechanism of triptolide in the treatment of connective tissue disease-related interstitial lung disease based on network pharmacology and molecular docking. PMID:35132912
Genome-wide association meta-analysis identifies 29 new acne susceptibility loci. PMID:35132056
Elucidating the material basis and potential mechanisms of Ershiwuwei Lvxue Pill acting on rheumatoid arthritis by UPLC-Q-TOF/MS and network pharmacology. PMID:35130279
Kaempferol and Apigenin suppresses the stemness properties of TNBC cells by modulating Sirtuins. PMID:35129762
The aqueous humor proteome is intrinsically disordered. PMID:35128080
Prognostic Bone Metastasis-Associated Immune-Related Genes Regulated by Transcription Factors in Mesothelioma. PMID:35127947
Molecular Mechanisms of Cardiac Injury Associated With Myocardial SARS-CoV-2 Infection. PMID:35127841
Single-Cell RNA-Seq Reveals the Promoting Role of Ferroptosis Tendency During Lung Adenocarcinoma EMT Progression. PMID:35127731
A Broad m6A Modification Landscape in Inflammatory Bowel Disease. PMID:35127705
A Preliminary Inquiry Into the Potential Mechanism of Huang-Lian-Jie-Du Decoction in Treating Rheumatoid Arthritis via Network Pharmacology and Molecular Docking. PMID:35127697
Identification of the hub genes and transcription factor-miRNA axes involved in Helicobacter pylori-associated gastric cancer. PMID:35126731
Identification of the Association Between Toll-Like Receptors and T-Cell Activation in Takayasu's Arteritis. PMID:35126357
Salvia miltiorrhiza Bge. (Danshen) for Inflammatory Bowel Disease: Clinical Evidence and Network Pharmacology-Based Strategy for Developing Supplementary Medical Application. PMID:35126100
Prediction of occult tumor progression via platelet RNAs in a mouse melanoma model: a potential new platform for early detection of cancer. PMID:35123499
Combined inhibition of XIAP and BCL2 drives maximal therapeutic efficacy in genetically diverse aggressive acute myeloid leukemia. PMID:35121960
Prognosis and tumor biology of pancreatic cancer patients with isolated lung metastases: translational results from the German multicenter AIO-YMO-PAK-0515 study. PMID:35121522
Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies. PMID:35119362
Comprehensive analysis of FKBP4/NR3C1/TMEM173 signaling pathway in triple-negative breast cancer cell and dendritic cell among tumor microenvironment. PMID:35118194
Exosomal miRNA Profiling is a Potential Screening Route for Non-Functional Pituitary Adenoma. PMID:35118066
Non-SMC condensin I complex subunit H (NCAPH), a regulator of cell cycle, predicts poor prognosis in lung adenocarcinoma patients: a study mainly based on TCGA and GEO database. PMID:35117357
Comprehensive analysis of the NME gene family functions in breast cancer. PMID:35117245
Bioinformatic analysis of the expression and prognosis of ZNF589 in human breast cancer. PMID:35116546
Functions of CXC chemokines as biomarkers and potential therapeutic targets in the hepatocellular carcinoma microenvironment. PMID:35116536
Identification of prognostic genes and tumor-infiltrating immune cells in the tumor microenvironment of esophageal squamous cell carcinoma and esophageal adenocarcinoma. PMID:35116502
Identification and validation of tumor microenvironment-related prognostic biomarkers in breast cancer. PMID:35116294
Random survival forest model identifies novel biomarkers of event-free survival in high-risk pediatric acute lymphoblastic leukemia. PMID:35116134
Anti-Liver Fibrosis Activity and the Potential Mode of Action of Ruangan Granules: Integrated Network Pharmacology and Metabolomics. PMID:35115923
Screening of compounds to identify novel epigenetic regulatory factors that affect innate immune memory in macrophages. PMID:35115604
Systems pharmacology-based drug discovery and active mechanism of natural products for coronavirus pneumonia (COVID-19): An example using flavonoids. PMID:35114443
Screening and identification of novel candidate biomarkers of focal cortical dysplasia type II via bioinformatics analysis. PMID:35112146
LCN2 as a Potential Diagnostic Biomarker for Ulcerative Colitis-Associated Carcinogenesis Related to Disease Duration. PMID:35111677
Integrated Analysis of Basic Helix Loop Helix Transcription Factor Family and Targeted Terpenoids Reveals Candidate AarbHLH Genes Involved in Terpenoid Biosynthesis in Artemisia argyi. PMID:35111184
Human Leucocyte Antigen G and Murine Qa-2 Are Critical for Myeloid Derived Suppressor Cell Expansion and Activation and for Successful Pregnancy Outcome. PMID:35111157
Autism genes converge on asynchronous development of shared neuron classes. PMID:35110736
DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor. PMID:35110406
DDX10 promotes the proliferation and metastasis of colorectal cancer cells via splicing RPL35. PMID:35109823
Quantitative proteomic analysis of GnRH agonist treated GBM cell line LN229 revealed regulatory proteins inhibiting cancer cell proliferation. PMID:35109816
Transcriptome landscape of early inflorescence developmental stages identifies key flowering time regulators in chickpea. PMID:35106703
PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation. PMID:35105861
Cytoplasmic switch of ARS2 isoforms promotes nonsense-mediated mRNA decay and arsenic sensitivity. PMID:35104878
Predicting Coupled Herbs for the Treatment of Hypertension Complicated with Coronary Heart Disease in Real-World Data Based on a Complex Network and Machine Learning. PMID:35103067
Splicing is an alternate oncogenic pathway activation mechanism in glioma. PMID:35102191
Coxiella burnetii Virulent Phase I and Avirulent Phase II Variants Differentially Manipulate Autophagy Pathway in Neutrophils. PMID:35100012
Novel stress granule-like structures are induced via a paracrine mechanism during viral infection. PMID:35098996
A network pharmacology approach to predict potential targets and mechanisms of "Ramulus Cinnamomi (cassiae) - Paeonia lactiflora" herb pair in the treatment of chronic pain with comorbid anxiety and depression. PMID:35098831
Potential roles of hsa_circ_000839 and hsa_circ_0005986 in breast cancer. PMID:35098570
Protein signatures to distinguish aggressive from indolent prostate cancer. PMID:35098564
Potential Clinical Value of Biomarker-Guided Emergency Triage for Thoracic Aortic Dissection. PMID:35096998
Screening and Identification of Novel Potential Biomarkers for Breast Cancer Brain Metastases. PMID:35096583
In-Silico Multi-Omics Analysis of the Functional Significance of Calmodulin 1 in Multiple Cancers. PMID:35096010
Gene Co-Expression Network Analysis Identifies Vitamin D-Associated Gene Modules in Adult Normal Rectal Epithelium Following Supplementation. PMID:35096006
Comprehensive Analysis of Hub Genes Associated With Competing Endogenous RNA Networks in Stroke Using Bioinformatics Analysis. PMID:35096003
Role of IGF2 in the Study of Development and Evolution of Prostate Cancer. PMID:35095996
Cytohesin-2/ARNO: A Novel Bridge Between Cell Migration and Immunoregulation in Synovial Fibroblasts. PMID:35095899
Analysis and Validation of Hub Genes in Blood Monocytes of Postmenopausal Osteoporosis Patients. PMID:35095774
Targeting HSP90 Inhibits Proliferation and Induces Apoptosis Through AKT1/ERK Pathway in Lung Cancer. PMID:35095481
Multiple Molecular Pathways Are Influenced by Progranulin in a Neuronal Cell Model-A Parallel Omics Approach. PMID:35095393
Genome-wide analysis reveals a rhamnolipid-dependent modulation of flagellar genes in Pseudomonas aeruginosa PAO1. PMID:35094149
The oncogenic role of treacle ribosome biogenesis factor 1 (TCOF1) in human tumors: a pan-cancer analysis. PMID:35093935
The miR-23b/27b/24-1 Cluster Inhibits Hepatic Fibrosis by Inactivating Hepatic Stellate Cells. PMID:35093591
Pan-cancer analysis combined with experiments explores the oncogenic role of spindle apparatus coiled-coil protein 1 (SPDL1). PMID:35093072
Making sense of the linear genome, gene function and TADs. PMID:35090532
Multi-omic landscaping of human midbrains identifies disease-relevant molecular targets and pathways in advanced-stage Parkinson's disease. PMID:35090094
Integrin-linked kinase (ILK): the known vs. the unknown and perspectives. PMID:35089438
Prediction of Mechanosensitive Genes in Vascular Endothelial Cells Under High Wall Shear Stress. PMID:35087573
Naringenin Regulates FKBP4/NR3C1/NRF2 Axis in Autophagy and Proliferation of Breast Cancer and Differentiation and Maturation of Dendritic Cell. PMID:35087512
High expression of tight junction protein 1 as a predictive biomarker for bladder cancer grade and staging. PMID:35087173
Progesterone differentially affects the transcriptomic profiles of cow endometrial cell types. PMID:35086476
A cluster of blood-based protein biomarkers reflecting coagulation relates to the burden of cerebral small vessel disease. PMID:35086368
Simple But Efficacious Enrichment of Integral Membrane Proteins and Their Interactions for In-Depth Membrane Proteomics. PMID:35085786
Proteomic profiling of cisplatin-resistant and cisplatin-sensitive germ cell tumour cell lines using quantitative mass spectrometry. PMID:35084545
Pyroptosis in glioblastoma: A crucial regulator of the tumour immune microenvironment and a predictor of prognosis. PMID:35083859
Matrin3: Disorder and ALS Pathogenesis. PMID:35083279
Elevated Expression of Gamma-Glutamyl Hydrolase Is Associated With Poor Prognosis and Altered Immune Signature in Uterine Corpus Endometrial Carcinoma. PMID:35082830
The Polygenic Map of Keloid Fibroblasts Reveals Fibrosis-Associated Gene Alterations in Inflammation and Immune Responses. PMID:35082796
APOA1 Level is Negatively Correlated with the Severity of COVID-19. PMID:35082518
Identification of let-7f and miR-338 as plasma-based biomarkers for sporadic amyotrophic lateral sclerosis using meta-analysis and empirical validation. PMID:35082326
Mitochondrial-nuclear epistasis underlying phenotypic variation in breast cancer pathology. PMID:35082309
Wounding response in Porifera (sponges) activates ancestral signaling cascades involved in animal healing, regeneration, and cancer. PMID:35079031
Bioinformatics screening the novel and promising targets of curcumin in hepatocellular carcinoma chemotherapy and prognosis. PMID:35078445
The role of SPI1-TYROBP-FCER1G network in oncogenesis and prognosis of osteosarcoma, and its association with immune infiltration. PMID:35078433
Overexpression of miR-200b-3p in Menstrual Blood-Derived Mesenchymal Stem Cells from Endometriosis Women. PMID:35075610
Phosphorylation-dependent proteome of Marcks in ependyma during aging and behavioral homeostasis in the mouse forebrain. PMID:35075585
Identification of Constituents and Exploring the Mechanism for Toutongning Capsule in the Treatment of Migraine. PMID:35075364
circVAMP3 Drives CAPRIN1 Phase Separation and Inhibits Hepatocellular Carcinoma by Suppressing c-Myc Translation. PMID:35072355
Identification of key genes associated with esophageal adenocarcinoma based on bioinformatics analysis. PMID:35071405
Antioxidant Effects and Potential Molecular Mechanism of Action of Limonium aureum Extract Based on Systematic Network Pharmacology. PMID:35071383
Comprehensive analysis of prognostic value and immune infiltration of calpains in pancreatic cancer. PMID:35070391
Identifies Immune Feature Genes for Prediction of Chemotherapy Benefit in Cancer. PMID:35069897
Immune-related gene expression in skin, inflamed and keloid tissue from patients with keloids. PMID:35069881
Identification of Therapeutic Targets and Prognostic Biomarkers among Genes from the Mediator Complex Family in the Hepatocellular Carcinoma Tumour-Immune Microenvironment. PMID:35069777
Comparison between Heat-Clearing Medicine and Antirheumatic Medicine in Treatment of Gastric Cancer Based on Network Pharmacology, Molecular Docking, and Tumor Immune Infiltration Analysis. PMID:35069767
Identification of Molecular Subtypes and Potential Small-Molecule Drugs for Esophagus Cancer Treatment Based on m6A Regulators. PMID:35069736
Landscape Analysis of Matrix Metalloproteinases Unveils Key Prognostic Markers for Patients With Breast Cancer. PMID:35069702
Comprehensive Pan-Cancer Genomic Analysis Reveals PHF19 as a Carcinogenic Indicator Related to Immune Infiltration and Prognosis of Hepatocellular Carcinoma. PMID:35069553
A Practical Strategy for Exploring the Pharmacological Mechanism of Luteolin Against COVID-19/Asthma Comorbidity: Findings of System Pharmacology and Bioinformatics Analysis. PMID:35069542
Transcriptome Profiling Based on Larvae at Different Time Points After Hatching Provides a Core Set of Gene Resource for Understanding the Metabolic Mechanisms of the Brood-Care Behavior in Octopus ocellatus. PMID:35069236
Utilizing network pharmacology and experimental validation to explore the potential molecular mechanisms of BanXia-YiYiRen in treating insomnia. PMID:35067174
A proteomics approach identifies novel resident zebrafish Balbiani body proteins Cirbpa and Cirbpb. PMID:35065906
Identification of differentially methylated genes in first-trimester placentas with trisomy 16. PMID:35064135
Prediction of Novel Drug Targets and Vaccine Candidates against Human Lice (Insecta), Acari (Arachnida), and Their Associated Pathogens. PMID:35062669
Homologous recombination DNA repair gene RAD51, XRCC2 & XRCC3 polymorphisms and breast cancer risk in South Indian women. PMID:35061678
Inverse Potts model improves accuracy of phylogenetic profiling. PMID:35060594
Bioinformatics analysis of recurrent deletion regions in neuroblastoma. PMID:35059899
Age-related differences in hamstring tendon used as autograft in reconstructive anterior cruciate ligament surgery. PMID:35059770
Thrombocytopenia in COVID‑19 and vaccine‑induced thrombotic thrombocytopenia. PMID:35059730
High-Mobility Group AT-Hook 1 Served as a Prognosis Biomarker and Associated with Immune Infiltrate in Hepatocellular Carcinoma. PMID:35058711
Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal disease. PMID:35057801
Changes in the Transcriptome Profiles of Human Amnion-Derived Mesenchymal Stromal/Stem Cells Induced by Three-Dimensional Culture: A Potential Priming Strategy to Improve Their Properties. PMID:35055049
Exosomal and Plasma Non-Coding RNA Signature Associated with Urinary Albumin Excretion in Hypertension. PMID:35055008
Searching for New Z-DNA/Z-RNA Binding Proteins Based on Structural Similarity to Experimentally Validated Zα Domain. PMID:35054954
Telomere and Telomerase-Associated Proteins in Endometrial Carcinogenesis and Cancer-Associated Survival. PMID:35054812
Characterization of the Role of Extracellular Vesicles Released from Chicken Tracheal Cells in the Antiviral Responses against Avian Influenza Virus. PMID:35054579
Identification of Tumor Antigens and Immune Subtypes for the Development of mRNA Vaccines and Individualized Immunotherapy in Soft Tissue Sarcoma. PMID:35053609
Correcting Differential Gene Expression Analysis for Cyto-Architectural Alterations in Substantia Nigra of Parkinson's Disease Patients Reveals Known and Potential Novel Disease-Associated Genes and Pathways. PMID:35053314
Smell Detection Agent Optimisation Framework and Systems Biology Approach to Detect Dys-Regulated Subnetwork in Cancer Data. PMID:35053185
Presence of a Mitovirus Is Associated with Alteration of the Mitochondrial Proteome, as Revealed by Protein-Protein Interaction (PPI) and Co-Expression Network Models in Chenopodium quinoa Plants. PMID:35053093
Computational pathology aids derivation of microRNA biomarker signals from Cytosponge samples. PMID:35051729
Mechanism research of Salvia miltiorrhiza on treating myocardial ischemia reperfusion injury according to network pharmacology combined with molecular docking technique. PMID:35049243
Identification of key genes and microRNAs for multiple sclerosis using bioinformatics analysis. PMID:35049167
Differential target multiplexed spinal cord stimulation programming modulates proteins involved in ion regulation in an animal model of neuropathic pain. PMID:35048719
Genetic and correlative light and electron microscopy evidence for the unique differentiation pathway of erythrophores in brown trout skin. PMID:35046436
Diffusion kernel-based predictive modeling of KRAS dependency in KRAS wild type cancer cell lines. PMID:35046405
STAT6 contributes to renal fibrosis by modulating PPARα-mediated tubular fatty acid oxidation. PMID:35046382
Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis. PMID:35045337
Comparative analysis of protein-protein interaction networks in metastatic breast cancer. PMID:35045088
Development of a CAFs-related gene signature to predict survival and drug response in bladder cancer. PMID:35044630
Multi-omic profiling of histone variant H3.3 lysine 27 methylation reveals a distinct role from canonical H3 in stem cell differentiation. PMID:35044400
Identification of a glioma functional network from gene fitness data using machine learning. PMID:35044082
TAF4b transcription networks regulating early oocyte differentiation. PMID:35043944
PRODeepSyn: predicting anticancer synergistic drug combinations by embedding cell lines with protein-protein interaction network. PMID:35043159
Designing of a bispecific antibody against SARS-CoV-2 spike glycoprotein targeting human entry receptors DPP4 and ACE2. PMID:35042653
Association between Arsenic Level, Gene Expression in Asian Population, and In Vitro Carcinogenic Bladder Tumor. PMID:35039759
Construction of a potential microRNA and messenger RNA regulatory network of acute lung injury in mice. PMID:35039607
Analysis of NIA and GSNOR family genes and nitric oxide homeostasis in response to wheat-leaf rust interaction. PMID:35039546
Deduction and exploration of the evolution and function of vertebrate GFPT family. PMID:35038160
The Highly Expressed IFIT1 in Nasopharyngeal Carcinoma Enhances Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma Cells. PMID:35038119
Inflammatory activation and immune cell infiltration are main biological characteristics of SARS-CoV-2 infected myocardium. PMID:35037831
Integrative multiomics and in silico analysis revealed the role of ARHGEF1 and its screened antagonist in mild and severe COVID-19 patients. PMID:35037717
The initial expression alterations occurring to transcription factors during the formation of breast cancer: Evidence from bioinformatics. PMID:35037412
Transcriptomic identification of HBx-associated hub genes in hepatocellular carcinoma. PMID:35036167
Identification and molecular characterization of the alternative spliced variants of beta carbonic anhydrase 1 (βCA1) from Arabidopsis thaliana. PMID:35036152
Pharmacological Mechanisms of Tinglizi against Chronic Heart Failure Determined by Network Pharmacology and Molecular Docking. PMID:35035498
Nitrogen use efficiency (NUE): elucidated mechanisms, mapped genes and gene networks in maize (Zea mays L.). PMID:35035142
Quantitative Metaproteomics and Activity-based Protein Profiling of Patient Fecal Microbiome Identifies Host and Microbial Serine-type Endopeptidase Activity Associated With Ulcerative Colitis. PMID:35033677
Decoding the role of macrophages in periodontitis and type 2 diabetes using single-cell RNA-sequencing. PMID:35032412
Mechanistic insights into the use of rhubarb in diabetic kidney disease treatment using network pharmacology. PMID:35029893
Proteomic Investigation in Plasma from Women with Fibromyalgia in Response to a 15-wk Resistance Exercise Intervention. PMID:35029590
Schisandrin B suppresses osteosarcoma lung metastasis in vivo by inhibiting the activation of the Wnt/β‑catenin and PI3K/Akt signaling pathways. PMID:35029287
Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson's disease. PMID:35027645
GLP2-GLP2R signal affects the viability and EGFR-TKIs sensitivity of PC9 and HCC827 cells. PMID:35027025
Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells. PMID:35024587
Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis in vivo. PMID:35024318
Shared genetic liability between major depressive disorder and osteoarthritis. PMID:35023758
Genome-wide in silico characterization and stress induced expression analysis of BcL-2 associated athanogene (BAG) family in Musa spp. PMID:35022483
Knowledge graph analytics platform with LINCS and IDG for Parkinson's disease target illumination. PMID:35021991
Chordin-like 1 is a novel prognostic biomarker and correlative with immune cell infiltration in lung adenocarcinoma. PMID:35021154
Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity. PMID:35020422
Identification of key tumor stroma-associated transcriptional signatures correlated with survival prognosis and tumor progression in breast cancer. PMID:35020130
Stimulation of adaptive gene amplification by origin firing under replication fork constraint. PMID:35018465
Genome-wide identification and expression profiling analysis of Wnt family genes affecting adipocyte differentiation in cattle. PMID:35017603
Comparative Analysis of T-Cell Spatial Proteomics and the Influence of HIV Expression. PMID:35017099
Functional analysis of the stable phosphoproteome reveals cancer vulnerabilities. PMID:35015814
Expression of type I interferon-associated genes at antiretroviral therapy interruption predicts HIV virological rebound. PMID:35013427
RNA-binding protein p54nrb/NONO potentiates nuclear EGFR-mediated tumorigenesis of triple-negative breast cancer. PMID:35013116
In-silico characterization and structure-based functional annotation of a hypothetical protein from Campylobacter jejuni involved in propionate catabolism. PMID:35012287
Comprehensive Molecular Landscape of Cetuximab Resistance in Head and Neck Cancer Cell Lines. PMID:35011716
The RNA-Binding Protein Musashi1 Regulates a Network of Cell Cycle Genes in Group 4 Medulloblastoma. PMID:35011618
The Omics Hunt for Novel Molecular Markers of Resistance to Phytophthora infestans. PMID:35009065
Arabidopsis thaliana Plant Natriuretic Peptide Active Domain Forms Amyloid-like Fibrils in a pH-Dependent Manner. PMID:35009013
Down-Regulation of miR-194-5p for Predicting Metastasis in Breast Cancer Cells. PMID:35008751
Combination of Genomic and Transcriptomic Approaches Highlights Vascular and Circadian Clock Components in Multiple Sclerosis. PMID:35008743
Meta-Analysis and Bioinformatics Detection of Susceptibility Genes in Diabetic Nephropathy. PMID:35008447
Novel Molecular Targets for Hepatocellular Carcinoma. PMID:35008303
Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease. PMID:35005195
COX-2/sEH Dual Inhibitor PTUPB Alleviates CCl 4 -Induced Liver Fibrosis and Portal Hypertension. PMID:35004731
Comprehensive Analysis Revealed that CDKN2A is a Biomarker for Immune Infiltrates in Multiple Cancers. PMID:35004697
Comprehensive Analysis of the Prognostic Values of the TRIM Family in Hepatocellular Carcinoma. PMID:35004288
Comprehensive Analyses of the Expression, Genetic Alteration, Prognosis Significance, and Interaction Networks of m6A Regulators Across Human Cancers. PMID:35003212
Inflammatory Cell Composition and Immune-Related microRNA Signature of Temporal Artery Biopsies From Patients With Giant Cell Arteritis. PMID:35003111
The In Vivo Transcriptomic Blueprint of Mycobacterium tuberculosis in the Lung. PMID:35003075
Analyses of circRNA and mRNA Profiles in Vogt-Koyanagi-Harada Disease. PMID:35003060
Host Factor Interaction Networks Identified by Integrative Bioinformatics Analysis Reveals Therapeutic Implications in COPD Patients With COVID-19. PMID:35002688
Cytochrome b561 Serves as a Potential Prognostic Biomarker and Target for Breast Cancer. PMID:35002301
Network analysis of host-pathogen protein interactions in microbe induced cardiovascular diseases. PMID:35001887
Identification of the molecular subgroups in asthma by gene expression profiles: airway inflammation implications. PMID:35000593
C2cd6-encoded CatSperτ targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane. PMID:34998468
Integrated weighted gene co-expression network analysis reveals biomarkers associated with prognosis of high-grade serous ovarian cancer. PMID:34997982
Evaluation of animal model congruence to human depression based on large-scale gene expression patterns of the CNS. PMID:34997033
Network models of prostate cancer immune microenvironments identify ROMO1 as heterogeneity and prognostic marker. PMID:34996995
Therapeutical interference with the epigenetic landscape of germ cell tumors: a comparative drug study and new mechanistical insights. PMID:34996497
Long-read transcriptome sequencing provides insight into lignan biosynthesis during fruit development in Schisandra chinensis. PMID:34996357
Limb development genes underlie variation in human fingerprint patterns. PMID:34995520
Phosphoglycerate mutase family member 5 maintains oocyte quality via mitochondrial dynamic rearrangement during aging. PMID:34995407
Inflammation Subtypes and Translating Inflammation-Related Genetic Findings in Schizophrenia and Related Psychoses: A Perspective on Pathways for Treatment Stratification and Novel Therapies. PMID:34995036
Quantitative Proteomic Analysis of Plasma Exosomes to Identify the Candidate Biomarker of Imatinib Resistance in Chronic Myeloid Leukemia Patients. PMID:34993140
Effects of Qinghuang Powder on Acute Myeloid Leukemia Based on Network Pharmacology, Molecular Docking, and In Vitro Experiments. PMID:34992668
Analysis of the Efficacy and Pharmacological Mechanisms of Action of Zhenren Yangzang Decoction on Ulcerative Colitis Using Meta-Analysis and Network Pharmacology. PMID:34992665
Key Phytochemicals and Biological Functions of Chuanxiong Rhizoma Against Ischemic Stroke: A Network Pharmacology and Experimental Assessment. PMID:34992531
Identification of COPA as a potential prognostic biomarker and pharmacological intervention target of cervical cancer by quantitative proteomics and experimental verification. PMID:34991628
Biochemical characterization of the interaction between KRAS and Argonaute 2. PMID:34988297
Trimethylamine-N-oxide-stimulated hepatocyte-derived exosomes promote inflammation and endothelial dysfunction through nuclear factor-kappa B signaling. PMID:34988179
Identification and Validation of Hub Genes Associated with Bladder Cancer by Integrated Bioinformatics and Experimental Assays. PMID:34988018
NHX Gene Family in Camellia sinensis: In-silico Genome-Wide Identification, Expression Profiles, and Regulatory Network Analysis. PMID:34987532
Integrated weighted gene coexpression network analysis identifies Frizzled 2 (FZD2) as a key gene in invasive malignant pleomorphic adenoma. PMID:34986855
Epigenetic modifications in pancreas development, diabetes, and therapeutics. PMID:34984701
CREB1K292 and HINFPK330 as Putative Common Therapeutic Targets in Alzheimer's and Parkinson's Disease. PMID:34984308
CircRTN4 promotes pancreatic cancer progression through a novel CircRNA-miRNA-lncRNA pathway and stabilizing epithelial-mesenchymal transition protein. PMID:34983537
Large-scale protein-protein post-translational modification extraction with distant supervision and confidence calibrated BioBERT. PMID:34983371
Effects of DISC1 on Alzheimer's disease cell models assessed by iTRAQ proteomics analysis. PMID:34981809
GFI1 Cooperates with IKZF1/IKAROS to Activate Gene Expression in T-cell Acute Lymphoblastic Leukemia. PMID:34980595
Meta-analysis Integrated With Multi-omics Data Analysis to Elucidate Pathogenic Mechanisms of Age-Related Knee Osteoarthritis in Mice. PMID:34979545
Analysis of Microarray Data from Medulloblastoma Tissue Samples. PMID:34978688
Identification in silico and expression analysis of a β-1-4-endoglucanase and β-galactosidase genes related to ripening in guava fruit. PMID:34978628
Implication of proliferation gene biomarkers in pulmonary hypertension. PMID:34977488
Based on Network Pharmacology Tools to Investigate the Mechanism of Tripterygium wilfordii Against IgA Nephropathy. PMID:34977095
The Tongue Squamous Carcinoma Cell Line Cal27 Primarily Employs Integrin α6β4-Containing Type II Hemidesmosomes for Adhesion Which Contribute to Anticancer Drug Sensitivity. PMID:34977030
Differentially Expressed Extracellular Vesicle, Exosome and Non-Exosome miRNA Profile in High and Low Tick-Resistant Beef Cattle. PMID:34976862
Network Pharmacology and Molecular Docking Analyses of Mechanisms Underlying Effects of the Cyperi Rhizoma-Chuanxiong Rhizoma Herb Pair on Depression. PMID:34976096
A Novel Competing Endogenous RNA Network Associated With the Pathogenesis of Graves' Ophthalmopathy. PMID:34976024
Synaptic Protein Phosphorylation Networks Are Associated With Electroacupuncture-Induced Circadian Control in the Suprachiasmatic Nucleus. PMID:34976011
Computational Prediction of Biomarkers, Pathways, and New Target Drugs in the Pathogenesis of Immune-Based Diseases Regarding Kidney Transplantation Rejection. PMID:34975915
Novel Insights Into Gene Signatures and Their Correlation With Immune Infiltration of Peripheral Blood Mononuclear Cells in Behcet's Disease. PMID:34975900
Differential Co-Expression Network Analysis Reveals Key Hub-High Traffic Genes as Potential Therapeutic Targets for COVID-19 Pandemic. PMID:34975885
Regionally Distinct Immune and Metabolic Transcriptional Responses in the Bovine Small Intestine and Draining Lymph Nodes During a Subclinical Mycobacterium avium subsp. paratuberculosis Infection. PMID:34975852
Understanding Gene Expression and Transcriptome Profiling of COVID-19: An Initiative Towards the Mapping of Protective Immunity Genes Against SARS-CoV-2 Infection. PMID:34975833
Breast Cancer Risk with Progestin Subdermal Implants: A Challenge in Patients Counseling. PMID:34975755
Robust T cell activation requires an eIF3-driven burst in T cell receptor translation. PMID:34970966
Multiplex-Heterogeneous Network-Based Capturing Potential SNP "Switches" of Pathways Associating With Diverse Disease Characteristics of Asthma. PMID:34970542
Comprehensive Analysis to Identify MAGEA3 Expression Correlated With Immune Infiltrates and Lymph Node Metastasis in Gastric Cancer. PMID:34970496
Strategies of tolerance reflected in two North American maple genomes. PMID:34967059
Increased levels of TAR DNA-binding protein 43 in the hippocampus of subjects with bipolar disorder: a postmortem study. PMID:34966974
High Expression of CEMIP Correlates Poor Prognosis and the Tumur Microenvironment in Breast Cancer as a Promisingly Prognostic Biomarker. PMID:34966410
Integration of System Biology Tools to Investigate Huperzine A as an Anti-Alzheimer Agent. PMID:34966281
Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors. PMID:34964899
Network pharmacology-based strategy to investigate the active ingredients and molecular mechanisms of Scutellaria Barbata D. Don against radiation pneumonitis. PMID:34964782
Bioinformatics study on different gene expression profiles of fibroblasts and vascular endothelial cells in keloids. PMID:34964740
Bioinformatics analysis of candidate genes and potential therapeutic drugs targeting adipose tissue in obesity. PMID:34964707
Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti-inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway. PMID:34964259
Mechanism of Elian granules in the treatment of precancerous lesions of gastric cancer in rats through the MAPK signalling pathway based on network pharmacology. PMID:34962453
Characterization of In Vivo Protein Complexes via Chemical Cross-Linking and Mass Spectrometry. PMID:34962381
Investigation and Computational Analysis of the Sulfotransferase (SOT) Gene Family in Potato (Solanum tuberosum): Insights into Sulfur Adjustment for Proper Development and Stimuli Responses. PMID:34961068
Dichotomous Responses to Chronic Fetal Hypoxia Lead to a Predetermined Aging Phenotype. PMID:34958949
Proteomic Analysis Reveals Low-Dose PARP Inhibitor-Induced Differential Protein Expression in BRCA1-Mutated High-Grade Serous Ovarian Cancer Cells. PMID:34958553
Proteogenomic Analysis Reveals Proteins Involved in the First Step of Adipogenesis in Human Adipose-Derived Stem Cells. PMID:34956370
Long Non-Coding RNA- Associated Competing Endogenous RNA Axes in T-Cells in Multiple Sclerosis. PMID:34956196
Screening for Active Compounds Targeting Human Natural Killer Cell Activation Identifying Daphnetin as an Enhancer for IFN-γ Production and Direct Cytotoxicity. PMID:34956168
Total Flavonoids of Chuju Decrease Oxidative Stress and Cell Apoptosis in Ischemic Stroke Rats: Network and Experimental Analyses. PMID:34955724
Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in schizophrenia. PMID:34952924
High GNG4 expression is associated with poor prognosis in patients with lung adenocarcinoma. PMID:34951127
A high-resolution mass spectrometry based proteomic dataset of human regulatory T cells. PMID:34950757
Nanostring technology on Fibrous Dysplasia bone biopsies. A pilot study suggesting different histology-related molecular profiles. PMID:34950753
Identification of a Five-Gene Signature Derived From MYCN Amplification and Establishment of a Nomogram for Predicting the Prognosis of Neuroblastoma. PMID:34950701
Identification and Validation of CYBB, CD86, and C3AR1 as the Key Genes Related to Macrophage Infiltration of Gastric Cancer. PMID:34950700
Comprehensive Analysis of the Effects of Genetic Ancestry and Genetic Characteristics on the Clinical Evolution of Oral Squamous Cell Carcinoma. PMID:34950653
Shu-Di-Huang and Gan-Cao Herb Pair Restored the Differentiation Potentials of Mesenchymal Stem Progenitors in Treating Osteoporosis via Downregulation of NF-κB Signaling Pathway. PMID:34950216
Identification and Clinical Validation of Key Extracellular Proteins as the Potential Biomarkers in Relapsing-Remitting Multiple Sclerosis. PMID:34950135
Proteomics Analysis of Tears and Saliva From Sjogren's Syndrome Patients. PMID:34950038
Inhibition of Podocytes DPP4 Activity Is a Potential Mechanism of Lobeliae Chinensis Herba in Treating Diabetic Kidney Disease. PMID:34950037
Computational Systems Pharmacology, Molecular Docking and Experiments Reveal the Protective Mechanism of Li-Da-Qian Mixture in the Treatment of Glomerulonephritis. PMID:34949932
GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data. PMID:34949163
SARS-CoV-2 Exacerbates Beta-Amyloid Neurotoxicity, Inflammation and Oxidative Stress in Alzheimer's Disease Patients. PMID:34948400
The Genome of the "Sea Vomit" Didemnum vexillum. PMID:34947908
NAPRT Expression Regulation Mechanisms: Novel Functions Predicted by a Bioinformatics Approach. PMID:34946971
Important Roles of Key Genes and Transcription Factors in Flower Color Differences of Nicotiana alata. PMID:34946925
Genome-Wide Analysis of the MADS-Box Gene Family in Maize: Gene Structure, Evolution, and Relationships. PMID:34946905
Machine Learning and Bioinformatics Framework Integration to Potential Familial DCM-Related Markers Discovery. PMID:34946895
Identification of a Novel Therapeutic Target against XDR Salmonella Typhi H58 Using Genomics Driven Approach Followed Up by Natural Products Virtual Screening. PMID:34946114
Transcription Regulation and Genome Rewiring Governing Sensitivity and Resistance to FOXM1 Inhibition in Breast Cancer. PMID:34944900
Integrative Analysis Identifies Multi-Omics Signatures That Drive Molecular Classification of Uveal Melanoma. PMID:34944787
8-Hydroxydaidzein Downregulates JAK/STAT, MMP, Oxidative Phosphorylation, and PI3K/AKT Pathways in K562 Cells. PMID:34944720
Activation of PPARα by Fenofibrate Attenuates the Effect of Local Heart High Dose Irradiation on the Mouse Cardiac Proteome. PMID:34944662
Deepening into Intracellular Signaling Landscape through Integrative Spatial Proteomics and Transcriptomics in a Lymphoma Model. PMID:34944421
Screening Analysis of Platelet miRNA Profile Revealed miR-142-3p as a Potential Biomarker in Modeling the Risk of Acute Coronary Syndrome. PMID:34944034
Deep Learning Analyses to Delineate the Molecular Remodeling Process after Myocardial Infarction. PMID:34943776
Genome-Wide RNAi Screening Identifies Novel Pathways/Genes Involved in Oxidative Stress and Repurposable Drugs to Preserve Cystic Fibrosis Airway Epithelial Cell Integrity. PMID:34943039
Proteomic profiling reveals engineered chitosan nanoparticles mediated cellular crosstalk and immunomodulation for therapeutic application in apical periodontitis. PMID:34938914
Identification of Therapeutic Targets and Prognostic Biomarkers Among Chemokine (C-C Motif) Ligands in the Liver Hepatocellular Carcinoma Microenvironment. PMID:34938730
Exome sequencing of deer mice on two California Channel Islands identifies potential adaptation to strongly contrasting ecological conditions. PMID:34938502
Bioinformatics-Based Analysis of lncRNA-mRNA Interaction Network of Mild Hepatic Encephalopathy in Cirrhosis. PMID:34938356
Anticancer Action of Xiaoxianxiong Tang in Non-Small Cell Lung Cancer by Pharmacological Analysis and Experimental Validation. PMID:34938346
Construction and Analysis of Immune Infiltration-Related ceRNA Network for Kidney Stones. PMID:34938320
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics. PMID:34936468
Allosteric inhibition of SHP2 uncovers aberrant TLR7 trafficking in aggravating psoriasis. PMID:34936223
An optimized genome-wide, virus-free CRISPR screen for mammalian cells. PMID:34935002
High miR-3609 expression is associated with better prognosis in TNBC based on mining using systematic integrated public sequencing data. PMID:34934431
Integrative Bioinformatics Analysis Revealed Mitochondrial Defects Underlying Hypoplastic Left Heart Syndrome. PMID:34934349
Transcriptome profiling identifies immune response genes against porcine reproductive and respiratory syndrome virus and Haemophilus parasuis co-infection in the lungs of piglets. PMID:34931503
Identification of Potential Genetic Biomarkers and Target Genes of Peri-Implantitis Using Bioinformatics Tools. PMID:34931168
De novo mutations in childhood cases of sudden unexplained death that disrupt intracellular Ca2+ regulation. PMID:34930847
Omicron N501Y mutation among SARS-CoV-2 lineages: Insilico analysis of potent binding to tyrosine kinase and hypothetical repurposed medicine. PMID:34929375
Identification of the Prognostic Value Among Suppressor Of Cytokine Signaling Family Members in Kidney Renal Clear Cell Carcinoma. PMID:34926570
LncRNA MSC-AS1 Is a Diagnostic Biomarker and Predicts Poor Prognosis in Patients With Gastric Cancer by Integrated Bioinformatics Analysis. PMID:34926534
KDM1A Identified as a Potential Oncogenic Driver and Prognostic Biomarker via Multi-Omics Analysis. PMID:34925656
Comprehensive Analysis to Identify Key Genes Involved in Advanced Atherosclerosis. PMID:34925641
Revealing the Mechanism of Astragali Radix against Cancer-Related Fatigue by Network Pharmacology and Molecular Docking. PMID:34925533
Pan-Cancer Analysis of the Solute Carrier Family 39 Genes in Relation to Oncogenic, Immune Infiltrating, and Therapeutic Targets. PMID:34925450
Prognostic Implications and Immune Infiltration Analysis of ALDOA in Lung Adenocarcinoma. PMID:34925439
Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer's Disease Brain Tissue Reveals Disease-Associated Signatures. PMID:34925024
Gender-sensitive word embeddings for healthcare. PMID:34918101
TP53 Mutation Infers a Poor Prognosis and Is Correlated to Immunocytes Infiltration in Breast Cancer. PMID:34917611
Identification of Hub Genes in Patients with Alzheimer Disease and Obstructive Sleep Apnea Syndrome Using Integrated Bioinformatics Analysis. PMID:34916831
GENPPI: standalone software for creating protein interaction networks from genomes. PMID:34915867
Genome-wide promoter analysis, homology modeling and protein interaction network of Dehydration Responsive Element Binding (DREB) gene family in Solanum tuberosum. PMID:34914734
Transcriptome Analysis of Large to Giant Congenital Melanocytic Nevus Reveals Cell Cycle Arrest and Immune Evasion: Identifying Potential Targets for Treatment. PMID:34912899
scNetViz: from single cells to networks using Cytoscape. PMID:34912541
Bioinformatics analysis for the role of CALR in human cancers. PMID:34910788
Protein-protein interactions: Methods, databases, and applications in virus-host study. PMID:34909403
Identification of transcriptional regulatory network associated with response of host epithelial cells to SARS-CoV-2. PMID:34907210
XDeathDB: a visualization platform for cell death molecular interactions. PMID:34907160
Prognostic value of CDCA3 in kidney renal papillary cell carcinoma. PMID:34905505
Multipopulational transcriptome analysis of post-weaned beef cattle at arrival further validates candidate biomarkers for predicting clinical bovine respiratory disease. PMID:34903778
Proteome and secretome profiling of zinc availability in Cryptococcus neoformans identifies Wos2 as a subtle influencer of fungal virulence determinants. PMID:34903172
Computational modeling of human-nCoV protein-protein interaction network. PMID:34902553
Case Report and Review of the Literature: Congenital Diaphragmatic Hernia and Craniosynostosis, a Coincidence or Common Cause? PMID:34900871
PCNA in Cervical Intraepithelial Neoplasia and Cervical Cancer: An Interaction Network Analysis of Differentially Expressed Genes. PMID:34900731
Plasma-Derived Extracellular Vesicles Reveal Galectin-3 Binding Protein as Potential Biomarker for Early Detection of Glioma. PMID:34900729
Network Pharmacology-Based Study on the Mechanism of Aloe Vera for Treating Cancer. PMID:34899953
Comprehensive Analyses of Type 1 Diabetes Ketosis- or Ketoacidosis-Related Genes in Activated CD56+CD16+ NK Cells. PMID:34899600
AS3MT Polymorphism: A Risk Factor for Epilepsy Susceptibility and Adverse Drug Reactions to Valproic Acid and Oxcarbazepine Treatment in Children From South China. PMID:34899152
Identifying Diagnostic and Prognostic Biomarkers and Candidate Therapeutic Drugs of Gastric Cancer Based on Transcriptomics and Single-Cell Sequencing. PMID:34899080
Exploration of the mechanism of luteolin against ischemic stroke based on network pharmacology, molecular docking and experimental verification. PMID:34898370
hsa_circ_0072389, hsa_circ_0072386, hsa_circ_0008621, hsa_circ_0072387, and hsa_circ_0072391 aggravate glioma via miR-338-5p/IKBIP. PMID:34897031
Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage. PMID:34896608
Prenatal Δ9-Tetrahydrocannabinol Exposure in Males Leads to Motivational Disturbances Related to Striatal Epigenetic Dysregulation. PMID:34895699
Regulatory modules of human thermogenic adipocytes: functional genomics of large cohort and Meta-analysis derived marker-genes. PMID:34895148
High Expression of VAV Gene Family Predicts Poor Prognosis of Acute Myeloid Leukemia. PMID:34894858
GDI2 is a novel diagnostic and prognostic biomarker in hepatocellular carcinoma. PMID:34894398
Integrative analysis of immune-related multi-omics profiles identifies distinct prognosis and tumor microenvironment patterns in osteosarcoma. PMID:34894177
Genetic determinants of endophytism in the Arabidopsis root mycobiome. PMID:34893598
Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder. PMID:34893581
Identification of prognostic and therapeutic value of CC chemokines in Urothelial bladder cancer: evidence from comprehensive bioinformatic analysis. PMID:34893045
Elucidating Drug-Like Compounds and Potential Mechanisms of Corn Silk (Stigma Maydis) against Obesity: A Network Pharmacology Study. PMID:34889899
Unsupervised construction of computational graphs for gene expression data with explicit structural inductive biases. PMID:34888618
Interrogating cell type-specific cooperation of transcriptional regulators in 3D chromatin. PMID:34888502
Integrative Analysis of Immune-Related Genes in the Tumor Microenvironment of Renal Clear Cell Carcinoma and Renal Papillary Cell Carcinoma. PMID:34888353
Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue-Multi-omics Insights From the Munich MIDY Pig Model. PMID:34888323
Clinical Value and Potential Mechanism of miRNA-33a-5p in Lung Squamous Cell Carcinoma. PMID:34888137
Prediction of the Molecular Mechanisms Underlying Erlong Zuoci Treatment of Age-Related Hearing Loss via Network Pharmacology-Based Analyses Combined with Experimental Validation. PMID:34887749
Fast and flexible analysis of linked microbiome data with mako. PMID:34887550
Strategies to package recombinant Adeno-Associated Virus expressing the N-terminal gasdermin domain for tumor treatment. PMID:34887423
The role of AKR1 family in tamoxifen resistant invasive lobular breast cancer based on data mining. PMID:34886806
Changes in the Proteome in the Development of Chronic Human Papillomavirus Infection-A Prospective Study in HIV Positive and HIV Negative Rwandan Women. PMID:34885095
Palm Oil-Rich Diet Affects Murine Liver Proteome and S-Palmitoylome. PMID:34884899
The Secretome of Human Neonatal Mesenchymal Stem Cells Modulates Doxorubicin-Induced Cytotoxicity: Impact in Non-Tumor Cells. PMID:34884877
A Comparative Transcriptomic Meta-Analysis Revealed Conserved Key Genes and Regulatory Networks Involved in Drought Tolerance in Cereal Crops. PMID:34884864
Homodimeric and Heterodimeric Interactions among Vertebrate Basic Helix-Loop-Helix Transcription Factors. PMID:34884664
A Dynamic Network of Proteins Facilitate Cell Envelope Biogenesis in Gram-Negative Bacteria. PMID:34884635
Splice-Variant Knock-Out of TGFβ Receptors Perturbates the Proteome of Ovarian Carcinoma Cells. PMID:34884451
PhosPiR: an automated phosphoproteomic pipeline in R. PMID:34882763
Identification of KLF6/PSGs and NPY-Related USF2/CEACAM Transcriptional Regulatory Networks via Spinal Cord Bulk and Single-Cell RNA-Seq Analysis. PMID:34880956
Exploration of the Key Proteins of High-Grade Intraepithelial Neoplasia to Adenocarcinoma Sequence Using In-Depth Quantitative Proteomics Analysis. PMID:34880916
Construction of a Support Vector Machine-Based Classifier for Pulmonary Arterial Hypertension Patients. PMID:34880909
High Expression of C1ORF112 Predicts a Poor Outcome: A Potential Target for the Treatment of Low-Grade Gliomas. PMID:34880897
Bioinformatic Analysis of Prognostic Value, Genetic Interaction, and Immune Infiltration of Chromobox Family Proteins in Breast Cancer. PMID:34880657
Identification and verification of the molecular mechanisms and prognostic values of the cadherin gene family in gastric cancer. PMID:34880371
Integrated analysis of the functions and prognostic values of RNA-binding proteins in neuroblastoma. PMID:34879089
Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes. PMID:34879078
Identification of ferroptosis-related genes as potential biomarkers of tongue squamous cell carcinoma using an integrated bioinformatics approach. PMID:34878732
Intermolecular Interactions Drive Protein Adaptive and Coadaptive Evolution at Both Species and Population Levels. PMID:34878126
Translating in vitro CFTR rescue into small molecule correctors for cystic fibrosis using the Library of Integrated Network-based Cellular Signatures drug discovery platform. PMID:34877817
Overexpression of 15-Hydroxyprostaglandin Dehydrogenase Inhibits A549 Lung Adenocarcinoma Cell Growth via Inducing Cell Cycle Arrest and Inhibiting Epithelial-Mesenchymal Transition. PMID:34876851
Characterization of the GATA Transcription Factor Family and Exploration of Their Relevance to Immune Infiltration and Tumor Microenvironment in Pancreatic Cancer. PMID:34876843
Trophoblast glycoprotein is a new candidate gene for Parkinson's disease. PMID:34876581
Epigenomic Changes after Acupuncture Treatment in Patients Suffering from Burnout. PMID:34875647
Combined Quantitative (Phospho)proteomics and Mass Spectrometry Imaging Reveal Temporal and Spatial Protein Changes in Human Intestinal Ischemia-Reperfusion. PMID:34874173
Hub Gene and Its Key Effects on Diffuse Large B-Cell Lymphoma by Weighted Gene Coexpression Network Analysis. PMID:34873574
Patient-matched analysis identifies deregulated networks in prostate cancer to guide personalized therapeutic intervention. PMID:34873462
Exploring the Antiglioma Mechanisms of Luteolin Based on Network Pharmacology and Experimental Verification. PMID:34873410
The impact of whole genome duplications on the human gene regulatory networks. PMID:34871317
Loss of an Intimin-Like Protein Encoded on a Uropathogenic E. coli Pathogenicity Island Reduces Inflammation and Affects Interactions with the Urothelium. PMID:34871042
Potential Molecular Targets of Tenofovir Disoproxil Fumarate for Alleviating Chronic Liver Diseases via a Non-Antiviral Effect in a Normal Mouse Model. PMID:34869594
Comprehensive Analysis and Identification of Prognostic Biomarkers and Therapeutic Targets Among FAM83 Family Members for Gastric Cancer. PMID:34869310
LIMD2 is a Prognostic and Predictive Marker in Patients With Esophageal Cancer Based on a ceRNA Network Analysis. PMID:34868263
Weighted Gene Co-Expression Network Analysis and Treatment Strategies of Tumor Recurrence-Associated Hub Genes in Lung Adenocarcinoma. PMID:34868230
Genetic Studies of Metabolic Syndrome in Arab Populations: A Systematic Review and Meta-Analysis. PMID:34868209
Metallothionein 3-Zinc Axis Suppresses Caspase-11 Inflammasome Activation and Impairs Antibacterial Immunity. PMID:34867993
A Bioactive Extract Rich in Triterpenic Acid and Polyphenols from Olea europaea Promotes Systemic Immunity and Protects Atlantic Salmon Smolts Against Furunculosis. PMID:34867959
RNA-Binding Protein Expression Alters Upon Differentiation of Human B Cells and T Cells. PMID:34867946
Computational Network Pharmacology-Based Strategy to Capture Key Functional Components and Decode the Mechanism of Chai-Hu-Shu-Gan-San in Treating Depression. PMID:34867413
Antidepressant Mechanism of Traditional Chinese Medicine Formula Xiaoyaosan in CUMS-Induced Depressed Mouse Model via RIPK1-RIPK3-MLKL Mediated Necroptosis Based on Network Pharmacology Analysis. PMID:34867405
Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis. PMID:34867397
Predicting the Prognosis of Esophageal Adenocarcinoma by a Pyroptosis-Related Gene Signature. PMID:34867395
The Pharmacological Mechanism of Guchangzhixie Capsule Against Experimental Colitis. PMID:34867387
Study of Neuronal Apoptosis ceRNA Network in Hippocampal Sclerosis of Human Temporal Lobe Epilepsy by RNA-Seq. PMID:34867172
Epigenome-wide association studies: current knowledge, strategies and recommendations. PMID:34863305
CCR9 initiates epithelial-mesenchymal transition by activating Wnt/β-catenin pathways to promote osteosarcoma metastasis. PMID:34863167
Transmembrane signaling molecules play a key role in the pathogenesis of IgA nephropathy: a weighted gene co-expression network analysis study. PMID:34861820
A proteomic atlas of ligand-receptor interactions at the ovine maternal-fetal interface reveals the role of histone lactylation in uterine remodeling. PMID:34861240
Automated High-Throughput Method for the Fast, Robust, and Reproducible Enrichment of Newly Synthesized Proteins. PMID:34860524
Multiomics profiling of the expression and prognosis of MCMs in endometrial carcinoma. PMID:34859821
Identifying essential genes across eukaryotes by machine learning. PMID:34859210
A Novel Mutation of the KLK6 Gene in a Family With Knee Osteoarthritis. PMID:34858488
LC-MS Based Draft Map of the Arabidopsis thaliana Nuclear Proteome and Protein Import in Pattern Triggered Immunity. PMID:34858452
A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation. PMID:34858137
Large-scale integration of the plasma proteome with genetics and disease. PMID:34857953
A computational exploration of resilience and evolvability of protein-protein interaction networks. PMID:34857859
Conditional transcriptional relationships may serve as cancer prognostic markers. PMID:34856998
Proteomic quantitative study of dorsal root ganglia and sciatic nerve in type 2 diabetic mice. PMID:34856394
Integrative Bioinformatics Analysis Reveals That Infarct-Mediated Overexpression of Potential miR-662/CREB1 Pathway-Induced Neuropeptide VIP Is Associated with the Risk of Atrial Fibrillation: A Correlation Analysis between Myocardial Electrophysiology and Neuroendocrine. PMID:34853624
A Novel Ferroptosis-Related Gene Signature to Predict Prognosis in Patients with Head and Neck Squamous Cell Carcinoma. PMID:34853622
Pan-cancer analysis of non-oncogene addiction to DNA repair. PMID:34853396
Vesicular and extravesicular protein analyses from the airspaces of ozone-exposed mice revealed signatures associated with mucoinflammatory lung disease. PMID:34853335
Identification of crucial genes involved in pathogenesis of regional weakening of the aortic wall. PMID:34852854
Daily rhythms in gene expression of the human parasite Schistosoma mansoni. PMID:34852797
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment. PMID:34852220
Time Series Transcriptomic Analysis of Bronchoalveolar Lavage Cells from Piglets Infected with Virulent or Low-Virulent Porcine Reproductive and Respiratory Syndrome Virus 1. PMID:34851149
Managing the life cycle of a portfolio of open data resources at the SIB Swiss Institute of Bioinformatics. PMID:34850820
Challenges and opportunities in network-based solutions for biological questions. PMID:34849568
Diversity and molecular network patterns of symptom phenotypes. PMID:34848731
Substrate Profiling of Mitochondrial Caseinolytic Protease P via a Site-Specific Photocrosslinking Approach. PMID:34847623
Integrative analysis of prognostic value and immune infiltration of spindle and kinetochore-associated family members in breast cancer. PMID:34845974
Microenvironment-associated gene HSD11B1 may serve as a prognostic biomarker in clear cell renal cell carcinoma: a study based on TCGA, RT‑qPCR, Western blotting, and immunohistochemistry. PMID:34845968
A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor. PMID:34843601
Transcriptome sequencing revealed the influence of blue light on the expression levels of light-stress response genes in Centella asiatica. PMID:34843573
Nucleo-cytoplasmic RNA distribution responsible for maintaining neuroinflammatory microenvironment. PMID:34843419
Non-coding RNAs and related molecules associated with form-deprivation myopia in mice. PMID:34841657
Comprehensive analysis of human chorionic membrane extracts regulating mesenchymal stem cells during osteogenesis. PMID:34841608
Comprehensive gene cluster analysis of head and neck squamous cell carcinoma TCGA RNA-seq data defines B cell immunity-related genes as a robust survival predictor. PMID:34841601
Human macrophage polarization in the response to Mycobacterium leprae genomic DNA. PMID:34841308
Proteome Analysis of the Hypothalamic Arcuate Nucleus in Chronic High-Fat Diet-Induced Obesity. PMID:34840970
The N6-Methyladenosine- (m6A-) Associated Genes Act as Strong Key Biomarkers for the Prognosis of Pancreatic Adenocarcinoma. PMID:34840598
Pathway Enrichment Analysis of Microarray Data Fom Human Penis of Diabetic and Peyronie's Patients, in Comparison With Diabetic Rat Erectile Dysfunction Models. PMID:34838480
Identifying the Predictive Role of Oxidative Stress Genes in the Prognosis of Glioma Patients. PMID:34836934
AGE-Rich Bread Crust Extract Boosts Oxidative Stress Interception via Stimulation of the NRF2 Pathway. PMID:34836129
Bioinformatics Analysis Identifies Precision Treatment with Paclitaxel for Hepatocellular Carcinoma Patients Harboring Mutant TP53 or Wild-Type CTNNB1 Gene. PMID:34834551
Role of Sex on the Genetic Susceptibility to Childhood Asthma in Latinos and African Americans. PMID:34834492
Diterpenes/Diterpenoids and Their Derivatives as Potential Bioactive Leads against Dengue Virus: A Computational and Network Pharmacology Study. PMID:34833913
Matrix Metalloproteinases Inhibition by Doxycycline Rescues Extracellular Matrix Organization and Partly Reverts Myofibroblast Differentiation in Hypermobile Ehlers-Danlos Syndrome Dermal Fibroblasts: A Potential Therapeutic Target? PMID:34831458
Impacts of p97 on Proteome Changes in Human Cells during Coronaviral Replication. PMID:34831176
Transcriptome Analysis of Testicular Aging in Mice. PMID:34831115
Quantitative Analysis of the Cardiac Phosphoproteome in Response to Acute β-Adrenergic Receptor Stimulation In Vivo. PMID:34830474
PAHs and PCBs Affect Functionally Intercorrelated Genes in the Sea Urchin Paracentrotus lividus Embryos. PMID:34830379
Proteomics of Cryptococcus neoformans: From the Lab to the Clinic. PMID:34830272
Excess Heritability Contribution of Alcohol Consumption Variants in the "Missing Heritability" of Type 2 Diabetes Mellitus. PMID:34830198
Ferroptosis Induction in Multiple Myeloma Cells Triggers DNA Methylation and Histone Modification Changes Associated with Cellular Senescence. PMID:34830117
Identification of NSP3 (SH2D3C) as a Prognostic Biomarker of Tumor Progression and Immune Evasion for Lung Cancer and Evaluation of Organosulfur Compounds from Allium sativum L. as Therapeutic Candidates. PMID:34829812
Identification of Disease-Related Genes That Are Common between Alzheimer's and Cardiovascular Disease Using Blood Genome-Wide Transcriptome Analysis. PMID:34829754
Integration and Visualization of Regulatory Elements and Variations of the EPAS1 Gene in Human. PMID:34828399
Effect of High Hydrostatic Pressure on Stress-Related dnaK, hrcA, and ctsR Expression Patterns in Selected Lactobacilli Strains. PMID:34828326
Detoxification, Hydrogen Sulphide Metabolism and Wound Healing Are the Main Functions That Differentiate Caecum Protein Expression from Ileum of Week-Old Chicken. PMID:34827887
Comprehensive Atlas of the Myelin Basic Protein Interaction Landscape. PMID:34827627
Identification of Prognostic Gene Biomarkers in Non-Small Cell Lung Cancer Progression by Integrated Bioinformatics Analysis. PMID:34827193
Comprehensive Analysis of CPA4 as a Poor Prognostic Biomarker Correlated with Immune Cells Infiltration in Bladder Cancer. PMID:34827136
In silico Methods for Identification of Potential Therapeutic Targets. PMID:34826045
Pilot Nanostring PanCancer pathway analysis of colon adenocarcinoma in a tertiary healthcare centre in Kerala, India. PMID:34824625
Identification of Genes Potentially Associated with Melanoma Tumorigenesis Through Co-Expression Network Analysis. PMID:34824546
Mechanism of quercetin therapeutic targets for Alzheimer disease and type 2 diabetes mellitus. PMID:34824300
A roadmap for metagenomic enzyme discovery. PMID:34821235
Interleukin 20 receptor A expression in colorectal cancer and its clinical significance. PMID:34820194
Development of a bioinformatics platform for analysis of quantitative transcriptomics and proteomics data: the OMnalysis. PMID:34820180
MicroRNA-337-3p impedes breast cancer progression by targeting cyclin-dependent kinase 1. PMID:34820014
Geometric network analysis provides prognostic information in patients with high grade serous carcinoma of the ovary treated with immune checkpoint inhibitors. PMID:34819508
ATR inhibition enables complete tumour regression in ALK-driven NB mouse models. PMID:34819497
Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis. PMID:34818551
Ten genes are considered as potential biomarkers for the diagnosis of dermatomyositis. PMID:34818375
Comparative proteomics reveals Cryptosporidium parvum manipulation of the host cell molecular expression and immune response. PMID:34818332
Genome-wide analysis of the Glutathione S-Transferase family in wild Medicago ruthenica and drought-tolerant breeding application of MruGSTU39 gene in cultivated alfalfa. PMID:34817619
Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells. PMID:34816099
A Genome-Wide Association Study Identifies Novel Risk Loci for Sarcopenia in a Taiwanese Population. PMID:34815687
The role of complement in the clinical course of hepatocellular carcinoma. PMID:34813686
Pharmacological Mechanism of Danggui-Sini Formula for Intervertebral Disc Degeneration: A Network Pharmacology Study. PMID:34805401
Immune Infiltration-Related Signature Predicts Risk Stratification and Immunotherapy Efficacy in Grade II and III Gliomas. PMID:34805164
A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity. PMID:34805145
Integrated Strategy of UHPLC-Q-TOF-MS and Molecular Networking for Identification of Diterpenoids from Euphorbia fischeriana Steud. and Prediction of the Anti-Breast-Cancer Mechanism by the Network Pharmacological Method. PMID:34804177
The Integrative Analysis of Thrombospondin Family Genes in Pan-Cancer Reveals that THBS2 Facilitates Gastrointestinal Cancer Metastasis. PMID:34804159
Prognostic Values and Clinical Significance of S100 Family Member's Individualized mRNA Expression in Pancreatic Adenocarcinoma. PMID:34804125
Identification of Potential Key Genes in the Pathogenesis of Chronic Obstructive Pulmonary Disease Through Bioinformatics Analysis. PMID:34804123
Heritability Enrichment of Immunoglobulin G N-Glycosylation in Specific Tissues. PMID:34804021
Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension. PMID:34803695
Integrating Network Pharmacology, Transcriptome and Artificial Intelligence for Investigating Into the Effect and Mechanism of Ning Fei Ping Xue Decoction Against the Acute Respiratory Distress Syndrome. PMID:34803679
Cornelia de Lange Syndrome as Paradigm of Chromatinopathies. PMID:34803598
Selecting Hub Genes and Predicting Target Genes of microRNAs in Tuberculosis via the Bioinformatics Analysis. PMID:34803519
Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density. PMID:34801069
Construction of circRNA-miRNA-mRNA network and identification of novel potential biomarkers for non-small cell lung cancer. PMID:34801043
The metabolic growth limitations of petite cells lacking the mitochondrial genome. PMID:34799698
Prognostic Value of E2F Transcription Factor Expression in Pancreatic Adenocarcinoma. PMID:34799547
Disruption of β-Catenin-Dependent Wnt Signaling in Colon Cancer Cells Remodels the Microenvironment to Promote Tumor Invasion. PMID:34799404
CD4+ effector T cells accelerate Alzheimer's disease in mice. PMID:34798897
Comparison of carbohydrate ABC importers from Mycobacterium tuberculosis. PMID:34798821
Discriminative feature of cells characterizes cell populations of interest by a small subset of genes. PMID:34797848
System Analysis of ROS-Related Genes in the Prognosis, Immune Infiltration, and Drug Sensitivity in Hepatocellular Carcinoma. PMID:34795841
Genome-Wide Identification of CBL-CIPK Gene Family in Honeysuckle (Lonicera japonica Thunb.) and Their Regulated Expression Under Salt Stress. PMID:34795693
Repeated exposure with short-term behavioral stress resolves pre-existing stress-induced depressive-like behavior in mice. PMID:34795225
Identification of the regulatory role of lncRNA HCG18 in myasthenia gravis by integrated bioinformatics and experimental analyses. PMID:34794447
ZNF76 predicts prognosis and response to platinum chemotherapy in human ovarian cancer. PMID:34793589
Global miRNA expression of bone marrow mesenchymal stem/stromal cells derived from Fanconi anemia patients. PMID:34792755
Transmission distortion and genetic incompatibilities between alleles in a multigenerational mouse advanced intercross line. PMID:34791189
Identification of Cross-Pathway Connections via Protein-Protein Interactions Linked to Altered States of Metabolic Enzymes in Cervical Cancer. PMID:34790674
Prognostic and immune infiltrates for the Chromobox (CBX) protein family in human pancreatic adenocarcinoma. PMID:34790394
Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb. PMID:34790349
Integrated Analysis of Expression and Prognostic Values of Acyl-CoA Dehydrogenase short-chain in Colorectal Cancer. PMID:34790035
PHI-base in 2022: a multi-species phenotype database for Pathogen-Host Interactions. PMID:34788826
Limits and potential of combined folding and docking. PMID:34788800
Proteomic identification of ruminal epithelial protein expression profiles in response to starter feed supplementation in pre-weaned lambs. PMID:34786500
Identification and Validation of Autophagy-Related Genes as Potential Biomarkers and Therapeutic Targets in Atrial Fibrillation. PMID:34785936
Network based analysis identifies TP53m-BRCA1/2wt-homologous recombination proficient (HRP) population with enhanced susceptibility to Vigil immunotherapy. PMID:34785763
Chemogenetic modulation of sensory neurons reveals their regulating role in melanoma progression. PMID:34784974
Hearing loss genes reveal patterns of adaptive evolution at the coding and non-coding levels in mammals. PMID:34784928
Role of Rho guanine nucleotide exchange factors in non-small cell lung cancer. PMID:34783629
CyFi-MAP: an interactive pathway-based resource for cystic fibrosis. PMID:34782688
The possible role of SRMS in colorectal cancer by bioinformatics analysis. PMID:34781983
STOML2 interacts with PHB through activating MAPK signaling pathway to promote colorectal Cancer proliferation. PMID:34781982
Hub microRNAs and genes in the development of atrial fibrillation identified by weighted gene co-expression network analysis. PMID:34781940
Machine learning and network medicine approaches for drug repositioning for COVID-19. PMID:34778851
Overcoming Acquired Epigenetic Resistance to BTK Inhibitors. PMID:34778802
Identification of Potential Osteoporosis miRNA Biomarkers Using Bioinformatics Approaches. PMID:34777562
Arabidopsis Target of Rapamycin Coordinates With Transcriptional and Epigenetic Machinery to Regulate Thermotolerance. PMID:34777423
Pathogenesis of Enamel-Renal Syndrome Associated Gingival Fibromatosis: A Proteomic Approach. PMID:34777248
Bioinformatics approach to identify common gene signatures of patients with coronavirus 2019 and lung adenocarcinoma. PMID:34775559
A Prostate Cancer Proteomics Database for SWATH-MS Based Protein Quantification. PMID:34771740
NTRK1/TrkA Signaling in Neuroblastoma Cells Induces Nuclear Reorganization and Intra-Nuclear Aggregation of Lamin A/C. PMID:34771457
Network-Based Analysis to Identify Drivers of Metastatic Prostate Cancer Using GoNetic. PMID:34771455
Trial Proteomic Qualitative and Quantitative Analysis of the Protein Matrix of Submandibular Sialoliths. PMID:34771131
Establishment of Human-Induced Pluripotent Stem Cell-Derived Neurons-A Promising In Vitro Model for a Molecular Study of Rabies Virus and Host Interaction. PMID:34769416
Selenoprotein DIO2 Is a Regulator of Mitochondrial Function, Morphology and UPRmt in Human Cardiomyocytes. PMID:34769334
Multi-Omics Approach to Elucidate Cerebrospinal Fluid Changes in Dogs with Intervertebral Disc Herniation. PMID:34769107
Proteome Analysis of Whole-Body Responses in Medaka Experimentally Exposed to Fish-Killing Dinoflagellate Karenia mikimotoi. PMID:34769058
Systematic Analysis of FASTK Gene Family Alterations in Cancer. PMID:34768773
Two TGA Transcription Factor Members from Hyper-Susceptible Soybean Exhibiting Significant Basal Resistance to Soybean mosaic virus. PMID:34768757
Putative Biomarkers for Acute Pulmonary Embolism in Exhaled Breath Condensate. PMID:34768685
Identification of potential pan-coronavirus therapies using a computational drug repurposing platform. PMID:34767922
Comprehensive quantitative characterization of the human term amnion proteome. PMID:34765964
Endothelial Dec1-PPARγ Axis Impairs Proliferation and Apoptosis Homeostasis Under Hypoxia in Pulmonary Arterial Hypertension. PMID:34765605
Transcriptional Repression of Ferritin Light Chain Increases Ferroptosis Sensitivity in Lung Adenocarcinoma. PMID:34765600
Computational methods for protein localization prediction. PMID:34765098
Metal utilization in genome-reduced bacteria: Do human mycoplasmas rely on iron? PMID:34765092
Overexpression of CXCL8 gene in Saudi colon cancer patients. PMID:34764737
Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction. PMID:34762860
Restoration of aged hematopoietic cells by their young counterparts through instructive microvesicles release. PMID:34762598
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes. PMID:34761192
Integrated bioinformatics analysis reveals dynamic candidate genes and signaling pathways involved in the progression and prognosis of diffuse large B-cell lymphoma. PMID:34760386
Na+/H+-Exchanger Family as Novel Prognostic Biomarkers in Colorectal Cancer. PMID:34759967
The Clinical Significance and Immunization of MSMO1 in Cervical Squamous Cell Carcinoma Based on Bioinformatics Analysis. PMID:34759952
The Prognostic and Immunological Value of Guanylate-Binding Proteins in Lower-Grade Glioma: Potential Markers or Not? PMID:34759950
The Single-Cell Transcriptomic Analysis of Prefrontal Pyramidal Cells and Interneurons Reveals the Neuronal Expression of Genes Encoding Antimicrobial Peptides and Immune Proteins. PMID:34759929
PangenomeNet: a pan-genome-based network reveals functional modules on antimicrobial resistome for Escherichia coli strains. PMID:34758735
A brain proteomic signature of incipient Alzheimer's disease in young APOE ε4 carriers identifies novel drug targets. PMID:34757788
A catalog of curated breast cancer genes. PMID:34755241
Interdependence of neural network dysfunction and microglial alterations in Alzheimer's disease-related models. PMID:34755090
Functional drug-target-disease network analysis of gene-phenotype connectivity for curcumin in hepatocellular carcinoma. PMID:34754622
Identification and validation of candidate genes dysregulated in alveolar macrophages of acute respiratory distress syndrome. PMID:34754619
Regulatory network of miRNA, lncRNA, transcription factor and target immune response genes in bovine mastitis. PMID:34753991
A Src-H3 acetylation signaling axis integrates macrophage mechanosensation with inflammatory response. PMID:34753038
Priority index: database of genetic targets in immune-mediated disease. PMID:34751399
Genomic characterization between strains selected for death-feigning duration for avoiding attack of a beetle. PMID:34750398
Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane. PMID:34749525
Artificial intelligence for the discovery of novel antimicrobial agents for emerging infectious diseases. PMID:34748992
GPRuler: Metabolic gene-protein-reaction rules automatic reconstruction. PMID:34748537
YTH domain family: potential prognostic targets and immune-associated biomarkers in hepatocellular carcinoma. PMID:34747720
The human telomeric proteome during telomere replication. PMID:34747482
JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics. PMID:34747401
Computational workflow for functional characterization of COVID-19 through secondary data analysis. PMID:34746856
Bioinformatic Evidence Reveals that Cell Cycle Correlated Genes Drive the Communication between Tumor Cells and the Tumor Microenvironment and Impact the Outcomes of Hepatocellular Carcinoma. PMID:34746301
Mechanistic Insight Into the Regulation of Immune-Related Genes Expression in Autism Spectrum Disorder. PMID:34746237
Comprehensive Analysis of IGFBPs as Biomarkers in Gastric Cancer. PMID:34745945
Network Biology Approaches to Achieve Precision Medicine in Inflammatory Bowel Disease. PMID:34745229
Recognition of DNA Methylation Molecular Features for Diagnosis and Prognosis in Gastric Cancer. PMID:34745226
Coffea arabica L. Resistant to Coffee Berry Borer (Hypothenemus hampei) Mediated by Expression of the Bacillus thuringiensis Cry10Aa Protein. PMID:34745196
International Prognostic Index-Based Immune Prognostic Model for Diffuse Large B-Cell Lymphoma. PMID:34745101
Identification of Novel Kinase-Transcription Factor-mRNA-miRNA Regulatory Network in Nasopharyngeal Carcinoma by Bioinformatics Analysis. PMID:34744455
BCG vaccination and the risk of COVID 19: A possible correlation. PMID:34742127
Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations. PMID:34741638
Unraveling the role of tomato Bcl-2-associated athanogene (BAG) proteins during abiotic stress response and fruit ripening. PMID:34741097
Fibromine is a multi-omics database and mining tool for target discovery in pulmonary fibrosis. PMID:34741074
Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: Pathologic, physiologic, and detailed molecular profiling. PMID:34740873
Cisd2 plays an essential role in corneal epithelial regeneration. PMID:34740104
Proteasome inhibition alters mitotic progression through the upregulation of centromeric α-Satellite RNAs. PMID:34739170
Integration Analysis of m6A Related Genes in Skin Cutaneous Melanoma and the Biological Function Research of the SPRR1B. PMID:34737950
Integrated Single-Cell Bioinformatics Analysis Reveals Intrinsic and Extrinsic Biological Characteristics of Hematopoietic Stem Cell Aging. PMID:34737765
Prognostic and Immune-Infiltrate Significance of miR-222-3p and Its Target Genes in Thyroid Cancer. PMID:34737762
DPP inhibition alters the CXCR3 axis and enhances NK and CD8+ T cell infiltration to improve anti-PD1 efficacy in murine models of pancreatic ductal adenocarcinoma. PMID:34737215
BDdb: a comprehensive platform for exploration and utilization of birth defect multi-omics data. PMID:34736471
In-silico genome wide analysis of Mitogen activated protein kinase kinase kinase gene family in C. sinensis. PMID:34735479
Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits. PMID:34734193
A novel immune-related ceRNA network that predicts prognosis and immunotherapy response in lung adenocarcinoma. PMID:34734036
Prognostic and tumor-immune infiltration cell signatures in tamoxifen-resistant breast cancers. PMID:34733726
Analysis of Multiple Human Tumor Cases Reveals the Carcinogenic Effects of PKP3. PMID:34733461
Development and Validation of a Novel Mitophagy-Related Gene Prognostic Signature for Hepatocellular Carcinoma Based on Immunoscore Classification of Tumor. PMID:34733329
Gene4HL: An Integrated Genetic Database for Hearing Loss. PMID:34733322
Integrated Network Analysis to Identify Key Modules and Potential Hub Genes Involved in Bovine Respiratory Disease: A Systems Biology Approach. PMID:34733317
Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes. PMID:34732713
Epigenetic adaptations of the masticatory mucosa to periodontal inflammation. PMID:34732256
Identification of diagnostic signatures in ulcerative colitis patients via bioinformatic analysis integrated with machine learning. PMID:34731452
New tale on LianHuaQingWen: IL6R/IL6/IL6ST complex is a potential target for COVID-19 treatment. PMID:34731090
The Moderately (D)efficient Enzyme: Catalysis-Related Damage In Vivo and Its Repair. PMID:34729986
An Autoantigen Profile from Jurkat T-Lymphoblasts Provides a Molecular Guide for Investigating Autoimmune Sequelae of COVID-19. PMID:34729561
High Expression of ERK-related RASGRF2 predicts Poor prognosis in patients with Stomach Adenocarcinoma and correlates with M2 macrophage. PMID:34729119
Proteogenomic discovery of sORF-encoded peptides associated with bacterial virulence in Yersinia pestis. PMID:34728737
Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression in Drosophila dissects recognition of multiple PPAR-γ associated gene regulation. PMID:34728675
Weighted gene co-expression network analysis to identify key modules and hub genes associated with paucigranulocytic asthma. PMID:34727921
DNAJB11 predicts a poor prognosis and is associated with immune infiltration in thyroid carcinoma: a bioinformatics analysis. PMID:34727750
Network-based protein-protein interaction prediction method maps perturbations of cancer interactome. PMID:34727106
Hypoxia induces DOT1L in articular cartilage to protect against osteoarthritis. PMID:34727094
Prognostic evaluation and immune infiltration analysis of five bioinformatic selected genes in hepatocellular carcinoma. PMID:34726341
Truncation of the TPR domain of OGT alters substrate and glycosite selection. PMID:34725712
Natural Compounds from Hatikana Extract Potentiate Antidiabetic Actions as Displayed by In Vivo Assays and Verified by Network Pharmacological Tools. PMID:34725640
Antisense oligonucleotide activity in tumour cells is influenced by intracellular LBPA distribution and extracellular vesicle recycling. PMID:34725463
Biomarkers in a socially exchanged /fluid reflect colony maturity, behavior, and distributed metabolism. PMID:34725037
Transcriptomic analysis of the Myxococcus xanthus FruA regulon, and comparative developmental transcriptomic analysis of two fruiting body forming species, Myxococcus xanthus and Myxococcus stipitatus. PMID:34724903
Gene Expression of Diverse Cryptococcus Isolates during Infection of the Human Central Nervous System. PMID:34724829
Transcriptomic Analysis Identifies Complement Component 3 as a Potential Predictive Biomarker for Chemotherapy Resistance in Colorectal Cancer. PMID:34722636
Genome-Wide Identification and Expression Analysis of AP2/ERF Transcription Factor Related to Drought Stress in Cultivated Peanut (Arachis hypogaea L.). PMID:34721538
Drug Repurposing for Atopic Dermatitis by Integration of Gene Networking and Genomic Information. PMID:34721386
An In-Silico, In-Vitro and In-Vivo Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis. PMID:34721014
Prediction of the Effects of Variants and Differential Expression of Key Host Genes ACE2, TMPRSS2, and FURIN in SARS-CoV-2 Pathogenesis: An In Silico Approach. PMID:34720581
Bortezomib is significantly beneficial for de novo pediatric AML patients with low phosphorylation of the NF-κB subunit RelA. PMID:34719869
A novel protein truncating mutation in L2HGDH causes L-2-hydroxyglutaric aciduria in a consanguineous Pakistani family. PMID:34719772
Analysis of immune-related key genes in Alzheimer's disease. PMID:34719321
Brain areas involved with obsessive-compulsive disorder present different DNA methylation modulation. PMID:34717534
Determining oncogenic patterns and cancer predisposition through the transcriptomic profile in Mitchell-Riley syndrome with heterotopic gastric mucosa and duodenal atresia: a case report. PMID:34715892
Proteo-transcriptomics meta-analysis identifies SUMO2 as a promising target in glioblastoma multiforme therapeutics. PMID:34715855
Centrality of drug targets in protein networks. PMID:34715787
Comprehensive functional network analysis and screening of deleterious pathogenic variants in non-syndromic hearing loss causative genes. PMID:34714320
Tumour-associated CD204+ microglia/macrophages accumulate in perivascular and perinecrotic niches and correlate with an interleukin-6-enriched inflammatory profile in glioblastoma. PMID:34713474
MOSGA 2: Comparative genomics and validation tools. PMID:34712396
Integrative meta-analysis of gene expression profiles identifies FEN1 and ENDOU as potential diagnostic biomarkers for cervical squamous cell carcinoma. PMID:34712364
Upregulation of GTPBP4 Promotes the Proliferation of Liver Cancer Cells. PMID:34712323
Oncogene-mediated metabolic gene signature predicts breast cancer outcome. PMID:34711841
A cis-regulatory element promoting increased transcription at low temperature in cultured ectothermic Drosophila cells. PMID:34711176
p21 produces a bioactive secretome that places stressed cells under immunosurveillance. PMID:34709885
SARS-CoV-2-host proteome interactions for antiviral drug discovery. PMID:34709727
Comprehensive Analysis of Hexokinase 2 Immune Infiltrates and m6A Related Genes in Human Esophageal Carcinoma. PMID:34708035
Analysing a Novel RNA-Binding-Protein-Related Prognostic Signature Highly Expressed in Breast Cancer. PMID:34707800
Mycoplasma genitalium and M. pneumoniae Regulate a Distinct Set of Protein-Coding Genes in Epithelial Cells. PMID:34707609
Magnolol upregulates CHRM1 to attenuate Amyloid-β-triggered neuronal injury through regulating the cAMP/PKA/CREB pathway. PMID:34705126
A Potential Three-Gene-Based Diagnostic Signature for Hypertension in Pregnancy. PMID:34703289
Identification of Three Core Secretome Genes Associated with Immune Infiltration in High Tumor Mutation Burden Across 14 Major Solid Tumors. PMID:34703282
Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy. PMID:34702323
Identification of MYH6 as the potential gene for human ischaemic cardiomyopathy. PMID:34697898
Elucidate multidimensionality of type 1 diabetes mellitus heterogeneity by multifaceted information. PMID:34697343
Identification and validation of an autophagy-related signature for predicting survival in lower-grade glioma. PMID:34696669
BAF45b Is Required for Efficient Zika Virus Infection of HAP1 Cells. PMID:34696437
Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability. PMID:34695608
Identification of novel genome-wide pleiotropic associations with oral inflammatory traits. PMID:34694461
DeepTrio: a ternary prediction system for protein-protein interaction using mask multiple parallel convolutional neural networks. PMID:34694333
Drug Repurposing for Alzheimer's Disease Based on Protein-Protein Interaction Network. PMID:34692825
Optical Coherence Tomography Angiography Characteristics Serve as Retinal Vein Occlusion Therapeutic Biomarkers for Dexamethasone Intravitreal Implant. PMID:34691285
TNF Patterns and Tumor Microenvironment Characterization in Head and Neck Squamous Cell Carcinoma. PMID:34691075
A ten-genes-based diagnostic signature for atherosclerosis. PMID:34688276
Proteomic analysis of peritoneal fluid identified COMP and TGFBI as new candidate biomarkers for endometriosis. PMID:34686725
Engineering digitizer circuits for chemical and genetic screens in human cells. PMID:34686672
The Long Terminal Repeats of ERV6 Are Activated in Pre-Implantation Embryos of Cynomolgus Monkey. PMID:34685690
Prognostic Significance of Dysregulated Epigenomic and Chromatin Modifiers in Cervical Cancer. PMID:34685645
Investigation of Neurodevelopmental Deficits of 22 q11.2 Deletion Syndrome with a Patient-iPSC-Derived Blood-Brain Barrier Model. PMID:34685556
The Effect of Impaired Polyamine Transport on Pneumococcal Transcriptome. PMID:34684271
Multiomics Identification of Potential Targets for Alzheimer Disease and Antrocin as a Therapeutic Candidate. PMID:34683848
Bacterial Membrane-Derived Vesicles Attenuate Vancomycin Activity against Methicillin-Resistant Staphylococcus aureus. PMID:34683376
Integrated Molecular Characterization to Reveal the Association between Kynurenine 3-Monooxygenase Expression and Tumorigenesis in Human Breast Cancers. PMID:34683090
Unraveling Protein Interactions between the Temperate Virus Bam35 and Its Bacillus Host Using an Integrative Yeast Two Hybrid-High Throughput Sequencing Approach. PMID:34681765
Multi-Omics Approach to Mitochondrial DNA Damage in Human Muscle Fibers. PMID:34681740
Computational Approach Reveals Pronociceptive Potential of Cannabidiol in Osteoarthritis: Role of Transient Receptor Potential Channels. PMID:34681188
Structural Protein Analysis of Driver Gene Mutations in Conjunctival Melanoma. PMID:34681018
Modulation of Global Gene Expression by Aneuploidy and CNV of Dosage Sensitive Regulatory Genes. PMID:34681000
Integrative Map of HIF1A Regulatory Elements and Variations. PMID:34680921
GWAS Meta-Analysis Reveals Shared Genes and Biological Pathways between Major Depressive Disorder and Insomnia. PMID:34680902
Expression Profiles and Prognostic Value of FABPs in Colorectal Adenocarcinomas. PMID:34680577
The Persistence of Hepatitis C Virus Infection in Hepatocytes Promotes Hepatocellular Carcinoma Progression by Pro-Inflammatory Interluekin-8 Expression. PMID:34680563
Role of Lamin A/C as Candidate Biomarker of Aggressiveness and Tumorigenicity in Glioblastoma Multiforme. PMID:34680461
Expression Profile and Prognostic Value of Wnt Signaling Pathway Molecules in Colorectal Cancer. PMID:34680448
Multi-Omics Reveals the Immunological Role and Prognostic Potential of Mitochondrial Ubiquitin Ligase MARCH5 in Human Breast Cancer. PMID:34680446
Prognostic Gene Signature for Squamous Cell Carcinoma with a Higher Risk for Treatment Failure and Accelerated MEK-ERK Pathway Activity. PMID:34680330
Text Mining for Building Biomedical Networks Using Cancer as a Case Study. PMID:34680062
Mining drug-target and drug-adverse drug reaction databases to identify target-adverse drug reaction relationships. PMID:34679164
Upregulation of a nuclear factor-kappa B-interacting immune gene network in mice cochleae with age-related hearing loss. PMID:34679122
Bioinformatics analysis identifies DYNC1I1 as prognosis marker in male patients with liver hepatocellular carcinoma. PMID:34679093
Drug target inference by mining transcriptional data using a novel graph convolutional network framework. PMID:34677780
Virtual screening of functional foods and dissecting their roles in modulating gene functions to support post COVID-19 complications. PMID:34676581
An Integrative Pan-Cancer Analysis of the Oncogenic Role of COPB2 in Human Tumors. PMID:34676262
Performance Assessment of the Network Reconstruction Approaches on Various Interactomes. PMID:34676243
Platelet Mediated Inflammation in Coronary Artery Disease with Type 2 Diabetes Patients. PMID:34675593
A novel multi-biomarker combination predicting relapse from long-term remission after discontinuation of biological drugs in rheumatoid arthritis. PMID:34675298
Identification of SUMO Targets Associated With the Pluripotent State in Human Stem Cells. PMID:34673284
Integrated multi-omics reveals common properties underlying stress granule and P-body formation. PMID:34672913
An Atypical Autoinflammatory Disease Due to an LRR Domain NLRP3 Mutation Enhancing Binding to NEK7. PMID:34671876
Identification of Significant Genes in Lung Cancer of Nonsmoking Women via Bioinformatics Analysis. PMID:34671675
Pan-Cancer Analysis of the Associations of TGFBI Expression With Prognosis and Immune Characteristics. PMID:34671645
Systematic Construction and Validation of a Prognostic Model for Hepatocellular Carcinoma Based on Immune-Related Genes. PMID:34671598
Exosome Released FZD10 Increases Ki-67 Expression via Phospho-ERK1/2 in Colorectal and Gastric Cancer. PMID:34671555
Defining the Innate Immune Responses for SARS-CoV-2-Human Macrophage Interactions. PMID:34671355
Proteomic Signatures of Human Visceral and Subcutaneous Adipocytes. PMID:34669916
Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates. PMID:34669475
Valsartan nano-filaments alter mitochondrial energetics and promote faster healing in diabetic rat wounds. PMID:34669222
mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity. PMID:34667149
Newborn infant skin gene expression: Remarkable differences versus adults. PMID:34665817
Identifying key genes and small molecule compounds for nasopharyngeal carcinoma by various bioinformatic analysis. PMID:34664875
Identification of key genes for HNSCC from public databases using bioinformatics analysis. PMID:34663338
Revealing the potential mechanism of Astragalus membranaceus improving prognosis of hepatocellular carcinoma by combining transcriptomics and network pharmacology. PMID:34663301
Network pharmacology and experimental investigation of Rhizoma polygonati extract targeted kinase with herbzyme activity for potent drug delivery. PMID:34662244
Probing the Peculiarity of EhRabX10, a pseudoRab GTPase, from the Enteric Parasite Entamoeba histolytica through In Silico Modeling and Docking Studies. PMID:34660804
Network Pharmacology-Based and Molecular Docking-Based Analysis of Suanzaoren Decoction for the Treatment of Parkinson's Disease with Sleep Disorder. PMID:34660782
Expression Levels of Three Key Genes CCNB1, CDC20, and CENPF in HCC Are Associated With Antitumor Immunity. PMID:34660300
MMS22L Expression as a Predictive Biomarker for the Efficacy of Neoadjuvant Chemoradiotherapy in Oesophageal Squamous Cell Carcinoma. PMID:34660277
Introducing physical exercise as a potential strategy in liver cancer prevention and development. PMID:34659659
Label-Free Liquid Chromatography-Mass Spectrometry Proteomic Analysis of the Urinary Proteome for Measuring the Escitalopram Treatment Response From Major Depressive Disorder. PMID:34658947
Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women With Alzheimer's Disease. PMID:34658838
m6A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin. PMID:34657574
Identification and quantification of immune infiltration landscape on therapy and prognosis in left- and right-sided colon cancer. PMID:34657172
Impact of human papillomavirus on the tumor microenvironment in oropharyngeal squamous cell carcinoma. PMID:34655477
Identification of cell cycle as the critical pathway modulated by exosome-derived microRNAs in gallbladder carcinoma. PMID:34655361
Tailored graphical lasso for data integration in gene network reconstruction. PMID:34654363
Text mining-based word representations for biomedical data analysis and protein-protein interaction networks in machine learning tasks. PMID:34653224
Sources of variability in nanoparticle uptake by cells. PMID:34652349
NR2F1-AS1 Promotes Pancreatic Ductal Adenocarcinoma Progression Through Competing Endogenous RNA Regulatory Network Constructed by Sponging miRNA-146a-5p/miRNA-877-5p. PMID:34650983
CDC45 modulates MCM7 expression and inhibits cell proliferation by suppressing the PI3K/AKT pathway in acute myeloid leukemia. PMID:34650692
Acute social isolation and regrouping cause short- and long-term molecular changes in the rat medial amygdala. PMID:34650208
Investigation of anti-osteoporosis mechanisms of Rehmanniae Radix Preparata based on network pharmacology and experimental verification. PMID:34649566
STAT1: a novel candidate biomarker and potential therapeutic target of the recurrent aphthous stomatitis. PMID:34649540
Cyclin-dependent kinase 19 upregulation correlates with an unfavorable prognosis in hepatocellular carcinoma. PMID:34649520
Exploring the Molecular Mechanism of Astragali Radix-Curcumae Rhizoma against Gastric Intraepithelial Neoplasia by Network Pharmacology and Molecular Docking. PMID:34646329
The expression, localisation and interactome of pigeon CRY2. PMID:34645873
GLUT4-overexpressing engineered muscle constructs as a therapeutic platform to normalize glycemia in diabetic mice. PMID:34644106
Powassan Viruses Spread Cell to Cell during Direct Isolation from Ixodes Ticks and Persistently Infect Human Brain Endothelial Cells and Pericytes. PMID:34643436
Protein co-expression network-based profiles revealed from laser-microdissected cancerous cells of lung squamous-cell carcinomas. PMID:34642392
Structural and functional consequences of NEDD8 phosphorylation. PMID:34642328
Integrated Network Pharmacology Analysis and In Vitro Validation Revealed the Potential Active Components and Underlying Mechanistic Pathways of Herba Patriniae in Colorectal Cancer. PMID:34641576
Network Pharmacology-Based Study to Uncover Potential Pharmacological Mechanisms of Korean Thistle (Cirsium japonicum var. maackii (Maxim.) Matsum.) Flower against Cancer. PMID:34641448
Neutrophil Pathways of Inflammation Characterize the Blood Transcriptomic Signature of Patients with Psoriasis and Cardiovascular Disease. PMID:34639156
Transcriptome and Proteome Analysis Revealed Key Pathways Regulating Final Stage of Oocyte Maturation of the Turkey (Meleagris gallopavo). PMID:34638931
Survivin' Acute Myeloid Leukaemia-A Personalised Target for inv(16) Patients. PMID:34638823
Risk Prediction of Cardiovascular Events by Exploration of Molecular Data with Explainable Artificial Intelligence. PMID:34638627
Regulation of ER Composition and Extent, and Putative Action in Protein Networks by ER/NE Protein TMEM147. PMID:34638576
Targeted Sequencing Revealed Distinct Mutational Profiles of Ocular and Extraocular Sebaceous Carcinomas. PMID:34638295
POU class 2 homeobox associating factor 1 (POU2AF1) participates in abdominal aortic aneurysm enlargement based on integrated bioinformatics analysis. PMID:34637689
Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment. PMID:34637165
FGF-2 induces a failure of cell cycle progression in cells harboring amplified K-Ras, revealing new insights into oncogene-induced senescence. PMID:34636387
IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay. PMID:34636324
Features of repertoire diversity and gene expression in human cytotoxic T cells following allogeneic hematopoietic cell transplantation. PMID:34635773
Butyrophilin-like 9 expression is associated with outcome in lung adenocarcinoma. PMID:34635082
High expression of transmembrane P24 trafficking protein 9 predicts poor prognosis in breast carcinoma. PMID:34635011
CDT1 Is a Novel Prognostic and Predictive Biomarkers for Hepatocellular Carcinoma. PMID:34631549
Scouting for common genes in the heterogenous hypoxic tumor microenvironment and their validation in glioblastoma. PMID:34631352
Getting to know each other: PPIMem, a novel approach for predicting transmembrane protein-protein complexes. PMID:34630938
Identification of Pulpitis-Related Potential Biomarkers Using Bioinformatics Approach. PMID:34630628
NetGenes: A Database of Essential Genes Predicted Using Features From Interaction Networks. PMID:34630517
A deep learning ensemble approach to prioritize antiviral drugs against novel coronavirus SARS-CoV-2 for COVID-19 drug repurposing. PMID:34630000
Hsp90-associated DNA replication checkpoint protein and proteasome-subunit components are involved in the age-related macular degeneration. PMID:34629418
Genome-wide analysis of DNA methylation in 106 schizophrenia family trios in Han Chinese. PMID:34628353
Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease. PMID:34628220
A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Lei-gong-gen formula granule on a spontaneously hypertensive rat model. PMID:34627325
MTDH associates with m6A RNA methylation and predicts cancer response for immune checkpoint treatment. PMID:34622157
Genome-Wide Identification and Evolutionary Analysis of the SRO Gene Family in Tomato. PMID:34621298
Neurodevelopmental Disorders in Patients With Complex Phenotypes and Potential Complex Genetic Basis Involving Non-Coding Genes, and Double CNVs. PMID:34621295
Network propagation-based prioritization of long tail genes in 17 cancer types. PMID:34620211
Identification of immunization-related new prognostic biomarkers for papillary renal cell carcinoma by integrated bioinformatics analysis. PMID:34620162
Two types of immune infiltrating cells and six hub genes can predict the occurrence of myasthenia gravis in patients with thymoma. PMID:34620045
An overview of machine learning methods for monotherapy drug response prediction. PMID:34619752
Multiomics approach reveals a role of translational machinery in shaping maize kernel amino acid composition. PMID:34618082
Testicular Nuclear Receptor 4 Regulates Proliferation and Apoptosis of Bladder Cancer via Bcl-2. PMID:34616769
Exosomal hsa-miR-21-5p is a biomarker for breast cancer diagnosis. PMID:34616615
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway. PMID:34616521
Room for Two: The Synaptophysin/Synaptobrevin Complex. PMID:34616284
Distinct roles of haspin in stem cell division and male gametogenesis. PMID:34615946
Genetic effects on longitudinal cognitive decline during the early stages of Alzheimer's disease. PMID:34615922
Genome-wide dynamic network analysis reveals the potential genes for MeJA-induced growth-to-defense transition. PMID:34615468
SMC-Derived Hyaluronan Modulates Vascular SMC Phenotype in Murine Atherosclerosis. PMID:34615369
Locus-specific analysis of Transposable Elements during the progression of ALS in the SOD1G93A mouse model. PMID:34614020
Low expression of endoplasmic reticulum stress-related gene SERP1 is associated with poor prognosis and immune infiltration in skin cutaneous melanoma. PMID:34613934
COVID-19 knowledge graph from semantic integration of biomedical literature and databases. PMID:34613368
Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy. PMID:34611171
Emerging evidence implicating a role for neurexins in neurodegenerative and neuropsychiatric disorders. PMID:34610269
Early reduction in PD-L1 expression predicts faster treatment response in human cutaneous leishmaniasis. PMID:34609968
Differentiable biology: using deep learning for biophysics-based and data-driven modeling of molecular mechanisms. PMID:34608321
Interaction of Male Specific Lethal complex and genomic imbalance on global gene expression in Drosophila. PMID:34608252
Iron homeostasis in the absence of ferricrocin and its consequences in fungal development and insect virulence in Beauveria bassiana. PMID:34608174
Foxd3 controls heterochromatin-mediated repression of repeat elements and 2-cell state transcription. PMID:34605600
Regulated splicing of large exons is linked to phase-separation of vertebrate transcription factors. PMID:34605568
CDKL5 kinase controls transcription-coupled responses to DNA damage. PMID:34605059
Transcriptome Analysis of Effects of Folic Acid Supplement on Gene Expression in Liver of Broiler Chickens. PMID:34604366
Genome-scale identification of plant defensin (PDF) family genes and molecular characterization of their responses to diverse nutrient stresses in allotetraploid rapeseed. PMID:34603847
PIK3CB is involved in metastasis through the regulation of cell adhesion to collagen I in pancreatic cancer. PMID:34603784
Identification of Novel COVID-19 Biomarkers by Multiple Feature Selection Strategies. PMID:34603483
PDZ Binding Kinase/T-LAK Cell-Derived Protein Kinase Plays an Oncogenic Role and Promotes Immune Escape in Human Tumors. PMID:34603451
A New Survival Model Based on ADAMTSs for Prognostic Prediction in Clear Cell Renal Cell Carcinoma. PMID:34603444
Integrative Analyses of Genes Associated With Right Ventricular Cardiomyopathy Induced by Tricuspid Regurgitation. PMID:34603374
Development of a Multi-Target Strategy for the Treatment of Vitiligo via Machine Learning and Network Analysis Methods. PMID:34603063
Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis. PMID:34603058
Bioinformatics and system biology approaches to identify pathophysiological impact of COVID-19 to the progression and severity of neurological diseases. PMID:34601390
Integrated bioinformatics analysis of core regulatory elements involved in keloid formation. PMID:34600545
Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors. PMID:34599019
Examining age-dependent DNA methylation patterns and gene expression in the male and female mouse hippocampus. PMID:34598831
A construction and comprehensive analysis of ceRNA networks and infiltrating immune cells in papillary renal cell carcinoma. PMID:34598322
Antimelanoma Effects of Concomitant Inhibition of SIRT1 and SIRT3 in BrafV600E/PtenNULL Mice. PMID:34597611
Atypical activation of signaling downstream of inactivated Bcr-Abl mediates chemoresistance in chronic myeloid leukemia. PMID:34596797
Quantitative phosphoproteomics reveals GSK3A substrate network is involved in the cryodamage of sperm motility. PMID:34596222
Network Pharmacology-Based Identification of Potential Targets of Lonicerae japonicae Flos Acting on Anti-Inflammatory Effects. PMID:34595237
AGTRAP Is a Prognostic Biomarker Correlated With Immune Infiltration in Hepatocellular Carcinoma. PMID:34595113
The Key Ingredient Acacetin in Weishu Decoction Alleviates Gastrointestinal Motility Disorder Based on Network Pharmacology Analysis. PMID:34594156
Bioinformatics Analyses Reveal the Prognostic Value and Biological Roles of SEPHS2 in Various Cancers. PMID:34594130
COVIDrugNet: a network-based web tool to investigate the drugs currently in clinical trial to contrast COVID-19. PMID:34593915
Network pharmacology-based investigation of potential targets of astragalus membranaceous-angelica sinensis compound acting on diabetic nephropathy. PMID:34593896
Transcriptomic analyses and experimental verification reveal potential biomarkers and biological pathways of urinary tract infection. PMID:34592898
A Novel Spectral Annotation Strategy Streamlines Reporting of Mono-ADP-ribosylated Peptides Derived from Mouse Liver and Spleen in Response to IFN-γ. PMID:34592425
Transcriptional profiling of macaque microglia reveals an evolutionary preserved gene expression program. PMID:34589771
Proteomic and molecular dynamic investigations of PTM-induced structural fluctuations in breast and ovarian cancer. PMID:34588485
Transcriptome profiling reveals new insights into the roles of neuronal nitric oxide synthase on macrophage polarization towards classically activated phenotype. PMID:34587205
CLPTM1L Is a Novel Putative Oncogene Promoting Tumorigenesis in Oral Squamous Cell Carcinoma. PMID:34586883
Exploration of the typical features of tubulovillous adenoma using in-depth quantitative proteomics analysis. PMID:34585630
Ciprofloxacin induced antibiotic resistance in Salmonella Typhimurium mutants and genome analysis. PMID:34585273
RNA-RNA interactions between SARS-CoV-2 and host benefit viral development and evolution during COVID-19 infection. PMID:34585235
Identification and validation of hub genes of synovial tissue for patients with osteoarthritis and rheumatoid arthritis. PMID:34583778
Multiscale Biology of Cardiovascular Risk in Psoriasis: Protocol for a Case-Control Study. PMID:34581684
Age-dependent changes in protein incorporation into collagen-rich tissues of mice by in vivo pulsed SILAC labelling. PMID:34581667
Bioinformatics Analysis of the MicroRNA-Metabolic Gene Regulatory Network in Neuropathic Pain and Prediction of Corresponding Potential Therapeutics. PMID:34580818
Identification of Potential Core Genes in Parkinson's Disease Using Bioinformatics Analysis. PMID:34580608
Network Pharmacology Reveals That Resveratrol Can Alleviate COVID-19-Related Hyperinflammation. PMID:34580601
Investigation of proteins important for microcirculation using in vivo microdialysis after glucose provocation: a proteomic study. PMID:34580391
Biologically relevant transfer learning improves transcription factor binding prediction. PMID:34579793
WRKY Transcription Factors in Cassava Contribute to Regulation of Tolerance and Susceptibility to Cassava Mosaic Disease through Stress Responses. PMID:34578401
Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus. PMID:34578187
Elucidating the Effects of Curcumin against Influenza Using In Silico and In Vitro Approaches. PMID:34577580
Deciphering the Dynamics of Signaling Cascades and Virulence Factors of B. cinerea during Tomato Cell Wall Degradation. PMID:34576732
Differential Regulation of Interferon Signaling Pathways in CD4+ T Cells of the Low Type-2 Obesity-Associated Asthma Phenotype. PMID:34576307
Association of miR-499 Polymorphism and Its Regulatory Networks with Hashimoto Thyroiditis Susceptibility: A Population-Based Case-Control Study. PMID:34576267
Analysis of Molecular Networks in the Cerebellum in Chronic Schizophrenia: Modulation by Early Postnatal Life Stressors in Murine Models. PMID:34576238
Hybrid Deep Learning Based on a Heterogeneous Network Profile for Functional Annotations of Plasmodium falciparum Genes. PMID:34576183
A Human Pan-Cancer System Analysis of Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 3 (PLOD3). PMID:34576068
The Lipid-Modulating Effect of Tangeretin on the Inhibition of Angiopoietin-like 3 (ANGPTL3) Gene Expression through Regulation of LXRα Activation in Hepatic Cells. PMID:34576019
Hypertensive Patients Exhibit Enhanced Thrombospondin-1 Levels at High-Altitude. PMID:34575042
The Link between Type 2 Diabetes Mellitus and the Polymorphisms of Glutathione-Metabolizing Genes Suggests a New Hypothesis Explaining Disease Initiation and Progression. PMID:34575035
Novel Approach Combining Transcriptional and Evolutionary Signatures to Identify New Multiciliation Genes. PMID:34573434
Identifying New Potential Biomarkers in Adrenocortical Tumors Based on mRNA Expression Data Using Machine Learning. PMID:34572898
Whole Blood Transcriptome Profiling Identifies DNA Replication and Cell Cycle Regulation as Early Marker of Response to Anti-PD-1 in Patients with Urothelial Cancer. PMID:34572887
Inhibition of UBA5 Expression and Induction of Autophagy in Breast Cancer Cells by Usenamine A. PMID:34572561
In Silico Characterization of Calcineurin from Pathogenic Obligate Intracellular Trypanosomatids: Potential New Biological Roles. PMID:34572535
Comparative Genomic Analysis of the DUF34 Protein Family Suggests Role as a Metal Ion Chaperone or Insertase. PMID:34572495
Cyclic Hypoxia Conditioning Alters the Content of Myoblast-Derived Extracellular Vesicles and Enhances Their Cell-Protective Functions. PMID:34572398
A Preclinical Investigation of GBM-N019 as a Potential Inhibitor of Glioblastoma via Exosomal mTOR/CDK6/STAT3 Signaling. PMID:34572040
Transcriptional Landscaping Identifies a Beige Adipocyte Depot in the Newborn Mouse. PMID:34572017
Autophagy-Associated IL-15 Production Is Involved in the Pathogenesis of Leprosy Type 1 Reaction. PMID:34571865
Predict long-range enhancer regulation based on protein-protein interactions between transcription factors. PMID:34570239
Heat Shock Proteins as Targets for Novel Antimalarial Drug Discovery. PMID:34569027
Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia. PMID:34568834
Biodata Mining of Differentially Expressed Genes between Acute Myocardial Infarction and Unstable Angina Based on Integrated Bioinformatics. PMID:34568491
Capturing Salmonella SspH2 Host Targets in Virus-Like Particles. PMID:34568381
Circular RNA hsa_circ_0000073 Enhances Osteosarcoma Cells Malignant Behavior by Sponging miR-1252-5p and Modulating CCNE2 and MDM2. PMID:34568326
Idebenone-Activating Autophagic Degradation of α-Synuclein via Inhibition of AKT-mTOR Pathway in a SH-SY5Y-A53T Model of Parkinson's Disease: A Network Pharmacological Approach. PMID:34567221
Immune Mechanism, Gene Module, and Molecular Subtype Identification of Astragalus Membranaceus in the Treatment of Dilated Cardiomyopathy: An Integrated Bioinformatics Study. PMID:34567206
Chromobox Homolog 8 (CBX8) in Human Tumor Carcinogenesis and Prognosis: A Pancancer Analysis Using Multiple Databases. PMID:34567093
Integrated Analysis of the Expression Characteristics, Prognostic Value, and Immune Characteristics of PPARG in Breast Cancer. PMID:34567087
Genome-Wide Analysis of the HSP20 Gene Family and Expression Patterns of HSP20 Genes in Response to Abiotic Stresses in Cynodon transvaalensis. PMID:34567082
Insights Into the Molecular Evolution of AT-Hook Motif Nuclear Localization Genes in Brassica napus. PMID:34567028
Shared Genetic Liability Between Major Depressive Disorder and Atopic Diseases. PMID:34566951
Systems-Level Proteomics Evaluation of Microglia Response to Tumor-Supportive Anti-Inflammatory Cytokines. PMID:34566949
Gene Signatures of NEUROGENIN3+ Endocrine Progenitor Cells in the Human Pancreas. PMID:34566896
Molecular Mechanism and Pathways of Normal Human Parturition in Different Gestational Tissues: A Systematic Review of Transcriptome Studies. PMID:34566691
Histone H3 lysine 27 acetylation profile undergoes two global shifts in undernourished children and suggests altered one-carbon metabolism. PMID:34565452
Clinical and functional characterization of a novel STUB1 frameshift mutation in autosomal dominant spinocerebellar ataxia type 48 (SCA48). PMID:34565360
Targeting the VCP-binding motif of ataxin-3 improves phenotypes in Drosophila models of Spinocerebellar Ataxia Type 3. PMID:34563642
Quantitative proteomic analysis after neuroprotective MyD88 inhibition in the retinal degeneration 10 mouse. PMID:34562309
CXCL10 and its related key genes as potential biomarkers for psoriasis: Evidence from bioinformatics and real-time quantitative polymerase chain reaction. PMID:34559160
RORα Enhances Lysosomal Acidification and Autophagic Flux in the Hepatocytes. PMID:34558854
Developmental programming and lineage branching of early human telencephalon. PMID:34558085
Systematic Analysis of the Impact of R-Methylation on RBPs-RNA Interactions: A Proteomic Approach. PMID:34557518
Topical Application of the PI3Kβ-Selective Small Molecule Inhibitor TGX-221 Is an Effective Treatment Option for Experimental Epidermolysis Bullosa Acquisita. PMID:34557502
Integrative Analysis of m6A Regulator-Mediated RNA Methylation Modification Patterns and Immune Characteristics in Lupus Nephritis. PMID:34557492
Early Leukocyte Responses in Ex-Vivo Models of Healing and Non-Healing Human Leishmania (Viannia) panamensis Infections. PMID:34557423
Integrated Analysis of Prognostic Genes Associated With Ischemia-Reperfusion Injury in Renal Transplantation. PMID:34557203
Callyspongiolide kills cells by inducing mitochondrial dysfunction via cellular iron depletion. PMID:34556786
MMP25-AS1/hsa-miR-10a-5p/SERPINE1 axis as a novel prognostic biomarker associated with immune cell infiltration in KIRC. PMID:34553021
Differential Expression of Immune Response Genes in Asymptomatic Chronic Chagas Disease Patients Versus Healthy Subjects. PMID:34552885
Exploring the Molecular Mechanism of Liuwei Dihuang Pills for Treating Diabetic Nephropathy by Combined Network Pharmacology and Molecular Docking. PMID:34552655
Novel Insights Into Cellular Changes in HPV8-E7 Positive Keratinocytes: A Transcriptomic and Proteomic Analysis. PMID:34552568
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing. PMID:34551807
PncsHub: a platform for annotating and analyzing non-classically secreted proteins in Gram-positive bacteria. PMID:34551435
Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity. PMID:34550965
Integrated Multi-omics, Virtual Screening and Molecular Docking Analysis of Methicillin-Resistant Staphylococcus aureus USA300 for the Identification of Potential Therapeutic Targets: An In-Silico Approach. PMID:34548853
SWATH-MS for prospective identification of protein blood biomarkers of rtPA-associated intracranial hemorrhage in acute ischemic stroke: a pilot study. PMID:34548538
Mechanism of Fuzheng Kang'ai Formula Regulating Tumor Microenvironment in Non-Small Cell Lung Cancer. PMID:34546538
A prion accelerates proliferation at the expense of lifespan. PMID:34545808
Xiaoyu Xiezhuo Drink Protects against Ischemia-Reperfusion Acute Kidney Injury in Aged Mice through Inhibiting the TGF-β1/Smad3 and HIF1 Signaling Pathways. PMID:34545331
Non-invasive diagnostic tool for Parkinson's disease by sebum RNA profile with machine learning. PMID:34545158
Multi-level inhibition of coronavirus replication by chemical ER stress. PMID:34545074
The Brachypodium distachyon cold-acclimated plasma membrane proteome is primed for stress resistance. PMID:34544140
Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings. PMID:34541468
Application of Genetic Algorithm-Based Support Vector Machine in Identification of Gene Expression Signatures for Psoriasis Classification: A Hybrid Model. PMID:34540995
Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer. PMID:34540372
Transcriptomic, Metabolomic, and Physiological Analyses Reveal That the Culture Temperatures Modulate the Cryotolerance and Embryogenicity of Developing Somatic Embryos in Picea glauca. PMID:34539690
Glycoprotein Pathways Altered in Frontotemporal Dementia With Autoimmune Disease. PMID:34539672
Augmented Expansion of Treg Cells From Healthy and Autoimmune Subjects via Adult Progenitor Cell Co-Culture. PMID:34539651
Preservation Analysis on Spatiotemporal Specific Co-expression Networks Suggests the Immunopathogenesis of Alzheimer's Disease. PMID:34539387
A Pan-Cancer Analysis of the Prognostic Value and Expression of Adenylate Cyclase 7 (ADCY7) in Human Tumors. PMID:34539183
KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases. PMID:34537014
D-SCRIPT translates genome to phenome with sequence-based, structure-aware, genome-scale predictions of protein-protein interactions. PMID:34536380
GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network. PMID:34533192
Network pharmacology study on the mechanism of Qiangzhifang in the treatment of panic disorder. PMID:34532487
Diagnostic biomarkers and potential drug targets for coronary artery disease as revealed by systematic analysis of lncRNA characteristics. PMID:34532380
Differential Abundance of Brain Mitochondrial Proteins in Yak and Cattle: A Proteomics-Based Study. PMID:34532350
Comprehensive Analysis of E2F Family Members in Human Gastric Cancer. PMID:34532281
Identification of hub genes and functional modules in colon adenocarcinoma based on public databases by bioinformatics analysis. PMID:34532115
PLCE1 Polymorphisms Are Associated With Gastric Cancer Risk: The Changes in Protein Spatial Structure May Play a Potential Role. PMID:34531897
DNA methylation changes following narrative exposure therapy in a randomized controlled trial with female former child soldiers. PMID:34531495
A membrane protein display platform for receptor interactome discovery. PMID:34531301
Potential mechanism of Ziyin Tongluo Formula in the treatment of postmenopausal osteoporosis: based on network pharmacology and ovariectomized rat model. PMID:34530875
TFTenricher: a python toolbox for annotation enrichment analysis of transcription factor target genes. PMID:34530727
The Spread of Spectrin in Ataxia and Neurodegenerative Disease. PMID:34528024
Network Pharmacology and Molecular Docking-Based Prediction of the Mechanism of Qianghuo Shengshi Decoction against Rheumatoid Arthritis. PMID:34527739
Pulmonary Neuroendocrine Neoplasms Overexpressing Epithelial-Mesenchymal Transition Mechanical Barriers Genes Lack Immune-Suppressive Response and Present an Increased Risk of Metastasis. PMID:34527572
The expression and potential mechanism of EGFR and EZH2 in breast cancer. PMID:34527565
Cryptic amyloidogenic regions in intrinsically disordered proteins: Function and disease association. PMID:34527192
Common Transcriptomic Effects of Abatacept and Other DMARDs on Rheumatoid Arthritis Synovial Tissue. PMID:34526997
NRXN1α+/- is associated with increased excitability in ASD iPSC-derived neurons. PMID:34525970
Finding functional associations between prokaryotic virus orthologous groups: a proof of concept. PMID:34525942
Antihypertensive drug treatment and susceptibility to SARS-CoV-2 infection in human PSC-derived cardiomyocytes and primary endothelial cells. PMID:34525378
Multiplexed drug-based selection and counterselection genetic manipulations in Drosophila. PMID:34525356
Immunophenotyping and Transcriptional Profiling of Human Plasmablasts in Dengue. PMID:34523972
Kohonen Artificial Neural Network and Multivariate Analysis in the Identification of Proteome Changes during Early and Long Aging of Bovine Longissimus dorsi Muscle Using SWATH Mass Spectrometry. PMID:34523341
The SUMO E3 ligase CBX4 is identified as a poor prognostic marker of gastric cancer through multipronged OMIC analyses. PMID:34522711
Integrated analysis of the molecular mechanisms in idiopathic pulmonary fibrosis. PMID:34522168
Programmed cell death 10 promotes metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma via PP2Ac-mediated YAP activation. PMID:34521817
Shortening of 3' UTRs in most cell types composing tumor tissues implicates alternative polyadenylation in protein metabolism. PMID:34521731
Formation of a protein corona on the surface of extracellular vesicles in blood plasma. PMID:34520123
Integrated weighted gene co-expression network analysis uncovers STAT1(signal transducer and activator of transcription 1) and IFI44L (interferon-induced protein 44-like) as key genes in pulmonary arterial hypertension. PMID:34516357
Investigation of Diagnostic Biomarkers for Osteoporosis Based on Differentially Expressed Gene Profile with QCT and mDixon-Quant Techniques. PMID:34516037
Effect of Tension on Human Periodontal Ligament Cells: Systematic Review and Network Analysis. PMID:34513810
RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers. PMID:34513691
Integrative Network Analysis Revealed Genetic Impact of Pyruvate Kinase L/R on Hepatocyte Proliferation and Graft Survival after Liver Transplantation. PMID:34512869
Identifying Protein Complexes With Clear Module Structure Using Pairwise Constraints in Protein Interaction Networks. PMID:34512712
YTHDF2 is a Potential Biomarker and Associated with Immune Infiltration in Kidney Renal Clear Cell Carcinoma. PMID:34512342
Network Pharmacology-Based Analysis on the Potential Biological Mechanisms of Sinisan Against Non-Alcoholic Fatty Liver Disease. PMID:34512330
Pro-Oncogenic c-Met/EGFR, Biomarker Signatures of the Tumor Microenvironment are Clinical and Therapy Response Prognosticators in Colorectal Cancer, and Therapeutic Targets of 3-Phenyl-2H-benzo[e][1,3]-Oxazine-2,4(3H)-Dione Derivatives. PMID:34512327
Identification of the Role of Wnt/β-Catenin Pathway Through Integrated Analyses and in vivo Experiments in Vitiligo. PMID:34511958
Scalable analysis of multi-modal biomedical data. PMID:34508579
An integrated analysis of mRNAs, lncRNAs, and miRNAs based on weighted gene co-expression network analysis involved in bovine endometritis. PMID:34508138
SWnet: a deep learning model for drug response prediction from cancer genomic signatures and compound chemical structures. PMID:34507532
From pyroptosis, apoptosis and necroptosis to PANoptosis: A mechanistic compendium of programmed cell death pathways. PMID:34504660
The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters. PMID:34504491
Identification of the Mouse T Cell ADP-Ribosylome Uncovers ARTC2.2 Mediated Regulation of CD73 by ADP-Ribosylation. PMID:34504490
PAL1 gene of the phenylpropanoid pathway increases resistance to the Cassava brown streak virus in cassava. PMID:34503522
A Transcriptomic Meta-Analysis Shows Lipid Metabolism Dysregulation as an Early Pathological Mechanism in the Spinal Cord of SOD1 Mice. PMID:34502460
A Multiplex CRISPR-Screen Identifies PLA2G4A as Prognostic Marker and Druggable Target for HOXA9 and MEIS1 Dependent AML. PMID:34502319
Network Pharmacology Study on Morus alba L. Leaves: Pivotal Functions of Bioactives on RAS Signaling Pathway and Its Associated Target Proteins against Gout. PMID:34502281
An O-GlcNAcylomic Approach Reveals ACLY as a Potential Target in Sepsis in the Young Rat. PMID:34502162
Tau Protein Interaction Partners and Their Roles in Alzheimer's Disease and Other Tauopathies. PMID:34502116
ViMIC: a database of human disease-related virus mutations, integration sites and cis-effects. PMID:34500462
Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine. PMID:34499080
Fur4-mediated uracil-scavenging to screen for surface protein regulators. PMID:34498791
Circulating circRNA as biomarkers for dilated cardiomyopathy etiology. PMID:34498126
Prognostic Biomarkers and Immunotherapeutic Targets Among CXC Chemokines in Pancreatic Adenocarcinoma. PMID:34497764
A Network Pharmacology Approach to Explore the Mechanism of HuangZhi YiShen Capsule for Treatment of Diabetic Kidney Disease. PMID:34497749
Construction on of a Ferroptosis-Related lncRNA-Based Model to Improve the Prognostic Evaluation of Gastric Cancer Patients Based on Bioinformatics. PMID:34497636
Activity-dependent modulation of synapse-regulating genes in astrocytes. PMID:34494546
Transcriptional analysis of the expression, prognostic value and immune infiltration activities of the COMMD protein family in hepatocellular carcinoma. PMID:34493238
Glutathione is an aging-related metabolic signature in the mouse kidney. PMID:34492635
Low expression of KIF20A suppresses cell proliferation, promotes chemosensitivity and is associated with better prognosis in HCC. PMID:34491228
Reconstruction of the Cytokine Signaling in Lysosomal Storage Diseases by Literature Mining and Network Analysis. PMID:34490253
TIMELESS Promotes Tumor Progression by Enhancing Macrophages Recruitment in Ovarian Cancer. PMID:34490127
Identification of Hub Genes Related to Liver Metastasis of Colorectal Cancer by Integrative Analysis. PMID:34490113
Whole Genome Sequence Data From Captive Baboons Implicate RBFOX1 in Epileptic Seizure Risk. PMID:34490042
Genetic Prioritization, Therapeutic Repositioning and Cross-Disease Comparisons Reveal Inflammatory Targets Tractable for Kidney Stone Disease. PMID:34489936
Interferon regulatory factor family influences tumor immunity and prognosis of patients with colorectal cancer. PMID:34488791
Inflammatory Pathways Are Impaired in Alzheimer Disease and Differentially Associated With Apolipoprotein E Status. PMID:34486652
A pan-cancer analysis of the prognostic and immunological role of β-actin (ACTB) in human cancers. PMID:34486492
A Two-Gene-Based Diagnostic Signature for Ruptured Intracranial Aneurysms. PMID:34485395
A 4-Gene Signature Associated With Recurrence in Low- and Intermediate-Risk Endometrial Cancer. PMID:34485158
Transcriptomic Analyses Reveal B-Cell Translocation Gene 2 as a Potential Therapeutic Target in Ovarian Cancer. PMID:34485119
Identifying Active Compounds and Mechanism of Camellia nitidissima Chi on Anti-Colon Cancer by Network Pharmacology and Experimental Validation. PMID:34484402
Genome-Wide Transcription Analysis of Electroacupuncture Precondition-Induced Ischemic Tolerance on SD Rat With Ischemia-Reperfusion Injury. PMID:34484305
Unravelling the Shared Genetic Mechanisms Underlying 18 Autoimmune Diseases Using a Systems Approach. PMID:34484189
Elucidating the Molecular Mechanism of Ischemic Stroke Using Integrated Analysis of miRNA, mRNA, and lncRNA Expression Profiles. PMID:34483854
DNA methylation changes in African American women with a history of preterm birth from the InterGEN study. PMID:34482817
Centromere protein E as a novel biomarker and potential therapeutic target for retinoblastoma. PMID:34482803
Proteomic signatures of myeloid derived suppressor cells from liver and lung metastases reveal functional divergence and potential therapeutic targets. PMID:34482371
Predictive and prognostic impact of ferroptosis-related genes ACSL4 and GPX4 on breast cancer treated with neoadjuvant chemotherapy. PMID:34482070
Single-cell transcriptome and cell-specific network analysis reveal the reparative effect of neurotrophin-4 in preantral follicles grown in vitro. PMID:34481496
Identification of HvLRX, a new dehydration and light responsive gene in Tibetan hulless barley (Hordeum vulgare var. nudum). PMID:34480266
Bioinformatics-based study to identify immune infiltration and inflammatory-related hub genes as biomarkers for the treatment of rheumatoid arthritis. PMID:34477936
Overexpression of TMEFF1 in Endometrial Carcinoma and the Mechanism Underlying its Promotion of Malignant Behavior in Cancer Cells. PMID:34475991
A prelude to the proximity interaction mapping of CXXC5. PMID:34475492
Transcriptional expression of ZICs as an independent indicator of survival in gliomas. PMID:34475426
The molecular feature of macrophages in tumor immune microenvironment of glioma patients. PMID:34471502
Predicting host dependency factors of pathogens in Drosophila melanogaster using machine learning. PMID:34471501
Exploring the Mechanism of Action of Herbal Medicine (Gan-Mai-Da-Zao Decoction) for Poststroke Depression Based on Network Pharmacology and Molecular Docking. PMID:34471414
iTRAQ-based quantitative proteomic analysis of the improved effects of total flavones of Dracocephalum Moldavica L. in chronic mountain sickness. PMID:34471201
Transcriptomic Responses to Coaggregation between Streptococcus gordonii and Streptococcus oralis. PMID:34469191
Transcription factors linked to the molecular signatures in the development of hepatocellular carcinoma on a cirrhotic background. PMID:34468893
Phenotyping Neurodegeneration in Human iPSCs. PMID:34465166
Exploring targets and signaling pathways of paeonol involved in relieving inflammation based on modern technology. PMID:34463943
A validated generally applicable approach using the systematic assessment of disease modules by GWAS reveals a multi-omic module strongly associated with risk factors in multiple sclerosis. PMID:34461822
Pro-inflammatory immunity supports fibrosis advancement in epidermolysis bullosa: intervention with Ang-(1-7). PMID:34459121
Comparative Proteomics of Human Milk From Eight Cities in China During Six Months of Lactation in the Chinese Human Milk Project Study. PMID:34458300
Redox Imbalance and Methylation Disturbances in Early Childhood Obesity. PMID:34457110
Mechanism Prediction of Astragalus membranaceus against Cisplatin-Induced Kidney Damage by Network Pharmacology and Molecular Docking. PMID:34457031
Proteome Landscape of Epithelial-to-Mesenchymal Transition (EMT) of Retinal Pigment Epithelium Shares Commonalities With Malignancy-Associated EMT. PMID:34455105
Differential resting-state patterns across networks are spatially associated with Comt and Trmt2a gene expression patterns in a mouse model of 22q11.2 deletion. PMID:34455061
Extracellular protein components of amyloid plaques and their roles in Alzheimer's disease pathology. PMID:34454574
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy. PMID:34453888
CXCL12/CXCR4 axis as a key mediator in atrial fibrillation via bioinformatics analysis and functional identification. PMID:34453039
Purinergic P2Y2 and P2X4 Receptors Are Involved in the Epithelial-Mesenchymal Transition and Metastatic Potential of Gastric Cancer Derived Cell Lines. PMID:34452195
Engineered EVs for Oxidative Stress Protection. PMID:34451800
In silico and gene expression analysis of the acute inflammatory response of gilthead seabream (Sparus aurata) after subcutaneous administration of carrageenin. PMID:34448108
Metagenome-assembled genome of a Chitinophaga sp. and its potential in plant biomass degradation, as well of affiliated Pandoraea and Labrys species. PMID:34448059
Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review. PMID:34447243
Epigenetic inactivation of the autophagy-lysosomal system in appendix in Parkinson's disease. PMID:34446734
Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity. PMID:34446728
Amnion signals are essential for mesoderm formation in primates. PMID:34446705
Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia. PMID:34446466
Expression profiles and functional prediction of long non-coding RNAs LINC01133, ZEB1-AS1 and ABHD11-AS1 in the luminal subtype of breast cancer. PMID:34446052
The Arabidopsis HY2 Gene Acts as a Positive Regulator of NaCl Signaling during Seed Germination. PMID:34445714
Drug Discovery of Spinal Muscular Atrophy (SMA) from the Computational Perspective: A Comprehensive Review. PMID:34445667
Identification and Classification of Novel Genetic Variants: En Route to the Diagnosis of Primary Ciliary Dyskinesia. PMID:34445527
Gibberellin Signaling Promotes the Secondary Growth of Storage Roots in Panax ginseng. PMID:34445398
Genetic and Epigenetic Alterations Induced by Pesticide Exposure: Integrated Analysis of Gene Expression, microRNA Expression, and DNA Methylation Datasets. PMID:34444445
Multi-Omics Analysis of SOX4, SOX11, and SOX12 Expression and the Associated Pathways in Human Cancers. PMID:34442467
Thermal Pain Thresholds Are Significantly Associated with Plasma Proteins of the Immune System in Chronic Widespread Pain-An Exploratory Pilot Study Using Multivariate and Network Analyses. PMID:34441948
An Integrative Systems Biology Approach Identifies Molecular Signatures Associated with Gallbladder Cancer Pathogenesis. PMID:34441816
Adenine Nucleotide Translocase 1 Expression Modulates the Immune Response in Ischemic Hearts. PMID:34440901
Overexpression and Activation of αvβ3 Integrin Differentially Affects TGFβ2 Signaling in Human Trabecular Meshwork Cells. PMID:34440692
Disparity of Hepatocellular Carcinoma in Tumor Microenvironment-Related Genes and Infiltrating Immune Cells between Asian and Non-Asian Populations. PMID:34440448
Bioinformatic Analysis of Two TOR (Target of Rapamycin)-Like Proteins Encoded by Entamoeba histolytica Revealed Structural Similarities with Functional Homologs. PMID:34440318
Proteomic Analysis Reveals Key Proteins in Extracellular Vesicles Cargo Associated with Idiopathic Pulmonary Fibrosis In Vitro. PMID:34440261
The Ups and Downs of STAT Inhibition in Acute Myeloid Leukemia. PMID:34440253
Survival-Based Biomarker Module Identification Associated with Oral Squamous Cell Carcinoma (OSCC). PMID:34439992
Uncovering Mechanisms of Zanthoxylum piperitum Fruits for the Alleviation of Rheumatoid Arthritis Based on Network Pharmacology. PMID:34439936
Epithelial Cell Line Derived from Endometriotic Lesion Mimics Macrophage Nervous Mechanism of Pain Generation on Proteome and Metabolome Levels. PMID:34439896
Isotopically Dimethyl Labeling-Based Quantitative Proteomic Analysis of Phosphoproteomes of Soybean Cultivars. PMID:34439883
GNAi2/gip2-Regulated Transcriptome and Its Therapeutic Significance in Ovarian Cancer. PMID:34439877
Identification of TSPAN4 as Novel Histamine H4 Receptor Interactor. PMID:34439793
Computational Approaches for Cancer-Fighting: From Gene Expression to Functional Foods. PMID:34439361
The Fatty Acid and Protein Profiles of Circulating CD81-Positive Small Extracellular Vesicles Are Associated with Disease Stage in Melanoma Patients. PMID:34439311
Pan-Cancer Analysis of Prognostic and Immune Infiltrates for CXCs. PMID:34439306
Molecular Changes Induced in Melanoma by Cell Culturing in 3D Alginate Hydrogels. PMID:34439267
PPAR-Responsive Elements Enriched with Alu Repeats May Contribute to Distinctive PPARγ-DNMT1 Interactions in the Genome. PMID:34439147
Genome-Wide Association Study Identifies Candidate Genes Associated with Feet and Leg Conformation Traits in Chinese Holstein Cattle. PMID:34438715
Comprehensive Transcriptomic Comparison between Porcine CD8- and CD8+ Gamma Delta T Cells Revealed Distinct Immune Phenotype. PMID:34438623
Variables Influencing Differences in Sequence Conservation in the Fission Yeast Schizosaccharomyces pombe. PMID:34436628
TCF19 Impacts a Network of Inflammatory and DNA Damage Response Genes in the Pancreatic β-Cell. PMID:34436454
RKC-B1 Blocks Activation of NF-κB and NLRP3 Signaling Pathways to Suppress Neuroinflammation in LPS-Stimulated Mice. PMID:34436268
H2O2 Induces Major Phosphorylation Changes in Critical Regulators of Signal Transduction, Gene Expression, Metabolism and Developmental Networks in Aspergillus nidulans. PMID:34436163
The Sex Differences in Uveal Melanoma: Potential Roles of EIF1AX, Immune Response and Redox Regulation. PMID:34436011
Alteration of immune profiles is associated with pulmonary function and symptoms in patients with chronic obstructive pulmonary disease. PMID:34435653
Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome. PMID:34435183
Establishment of a ferroptosis-related gene signature for prognosis in lung adenocarcinoma patients. PMID:34434660
Identification of miRNA-target gene regulatory networks in liver fibrosis based on bioinformatics analysis. PMID:34434654
Identification of a circRNA-miRNA-mRNA regulatory network for exploring novel therapeutic options for glioma. PMID:34434651
A Network Pharmacology Approach for Exploring the Mechanisms of Panax notoginseng Saponins in Ischaemic Stroke. PMID:34434246
Cost-Effective Mapping of Genetic Interactions in Mammalian Cells. PMID:34434222
Ferroptosis-Related Genes in Lung Adenocarcinoma: Prognostic Signature and Immune, Drug Resistance, Mutation Analysis. PMID:34434214
Comprehensive mapping of SARS-CoV-2 interactions in vivo reveals functional virus-host interactions. PMID:34433821
Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability. PMID:34433485
How to Achieve Therapeutic Response in Erlotinib-Resistant Head and Neck Squamous Cell Carcinoma? New Insights from Stable Isotope Labeling with Amino Acids in Cell Culture-Based Quantitative Tyrosine Phosphoproteomics. PMID:34432535
CANVS: an easy-to-use application for the analysis and visualization of mass spectrometry-based protein-protein interaction/association data. PMID:34432510
A Risk Signature Consisting of Eight m6A Methylation Regulators Predicts the Prognosis of Glioma. PMID:34432221
Plasma proteomic profiling reveals biomarkers associated with aortic dilation in patients with bicuspid aortic valve. PMID:34430623
AKT3 and related molecules as potential biomarkers responsible for cryptorchidism and cryptorchidism-induced azoospermia. PMID:34430428
Potential Arabidopsis thaliana glucosinolate genes identified from the co-expression modules using graph clustering approach. PMID:34430080
Tripterygium wilfordii derivative LLDT-8 targets CD2 in the treatment of rheumatoid arthritis. PMID:34429967
Identification of GNA12-driven gene signatures and key signaling networks in ovarian cancer. PMID:34429759
The Role of Adenosine Receptor A2A in the Regulation of Macrophage Exosomes and Vascular Endothelial Cells During Bone Healing. PMID:34429631
A Novel STK4 Mutation Impairs T Cell Immunity Through Dysregulation of Cytokine-Induced Adhesion and Chemotaxis Genes. PMID:34427831
A Model of Waardenburg Syndrome Using Patient-Derived iPSCs With a SOX10 Mutation Displays Compromised Maturation and Function of the Neural Crest That Involves Inner Ear Development. PMID:34426786
Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction. PMID:34424810
Transcriptomic analysis of human brains with Alzheimer's disease reveals the altered expression of synaptic genes linked to cognitive deficits. PMID:34423299
Comprehensive Analysis of Glycolysis-Related Genes for Prognosis, Immune Features, and Candidate Drug Development in Colon Cancer. PMID:34422808
CD86 Molecule Might Be a Novel Immune-Related Prognostic Biomarker for Patients With Bladder Cancer by Bioinformatics and Experimental Assays. PMID:34422632
Identification of Candidate Biomarkers and Prognostic Analysis in Colorectal Cancer Liver Metastases. PMID:34422629
Mining Natural Products with Anticancer Biological Activity through a Systems Biology Approach. PMID:34422220
Ameliorative Effects and Mechanism of Buyang Huanwu Decoction on Pulmonary Vascular Remodeling: Network and Experimental Analyses. PMID:34422208
Construction and Validation of a Novel Prognostic Signature for Intestinal Type of Gastric Cancer. PMID:34422135
Identification of Potential Bioactive Ingredients and Mechanisms of the Guanxin Suhe Pill on Angina Pectoris by Integrating Network Pharmacology and Molecular Docking. PMID:34422068
The Prognostic Value and Function of HOXB5 in Acute Myeloid Leukemia. PMID:34421991
Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats. PMID:34419102
Target identification of hepatic fibrosis using Pien Tze Huang based on mRNA and lncRNA. PMID:34417500
MethylSPWNet and MethylCapsNet: Biologically Motivated Organization of DNAm Neural Networks, Inspired by Capsule Networks. PMID:34417465
Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus. PMID:34416903
Bioinformatics analysis of constructing a HCV-related hepatocellular carcinoma miRNA-mRNA regulation network. PMID:34414965
Comprehensive Characterization of RNA Processing Factors in Gastric Cancer Identifies a Prognostic Signature for Predicting Clinical Outcomes and Therapeutic Responses. PMID:34413861
SARS-CoV-2 infection initiates interleukin-17-enriched transcriptional response in different cells from multiple organs. PMID:34413339
Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery. PMID:34412701
Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts. PMID:34412594
Ten simple rules for creating reusable pathway models for computational analysis and visualization. PMID:34411100
Identification of TIA1 mRNA targets during human neuronal development. PMID:34410578
Integrated Analysis of a Competing Endogenous RNA Network Reveals a Prognostic lncRNA Signature in Bladder Cancer. PMID:34408977
Mechanism-Centric Approaches for Biomarker Detection and Precision Therapeutics in Cancer. PMID:34408770
Environmental stress leads to genome streamlining in a widely distributed species of soil bacteria. PMID:34408268
Metabolic, structural, and proteomic changes in Candida albicans cells induced by the protein-carbohydrate fraction of Dendrobaena veneta coelomic fluid. PMID:34408181
PhenoDB, GeneMatcher and VariantMatcher, tools for analysis and sharing of sequence data. PMID:34407837
Extended mining of the oil biosynthesis pathway in biofuel plant Jatropha curcas by combined analysis of transcriptome and gene interactome data. PMID:34407772
RNA sequencing and functional studies of patient-derived cells reveal that neurexin-1 and regulators of this pathway are associated with poor outcomes in Ewing sarcoma. PMID:34403115
Distinct Persistence Fate of Mycobacterium tuberculosis in Various Types of Cells. PMID:34402643
Systematic analysis of Long non-coding RNAs reveals diagnostic biomarkers and potential therapeutic drugs for intervertebral disc degeneration. PMID:34402383
Genome-wide study of copy number variation implicates multiple novel loci for schizophrenia risk in Han Chinese family trios. PMID:34401673
CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity. PMID:34401662
Systems level insights into the impact of airborne exposure on SARS-CoV-2 pathogenesis and COVID-19 outcome - A multi-omics big data study. PMID:34401607
The acute phase protein lactoferrin is a key feature of Alzheimer's disease and predictor of Aβ burden through induction of APP amyloidogenic processing. PMID:34400772
Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants. PMID:34399844
Drug-repurposing against COVID-19 by targeting a key signaling pathway: An in silico study. PMID:34399157
Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression. PMID:34398873
A novel RNA binding protein-associated prognostic model to predict overall survival in hepatocellular carcinoma patients. PMID:34398005
Construction of a Potentially Functional circRNA-miRNA-mRNA Network in Intervertebral Disc Degeneration by Bioinformatics Analysis. PMID:34395625
Prognostic Prediction, Immune Microenvironment, and Drug Resistance Value of Collagen Type I Alpha 1 Chain: From Gastrointestinal Cancers to Pan-Cancer Analysis. PMID:34395525
Whole-Genome Sequencing Reveals Exonic Variation of ASIC5 Gene Results in Recurrent Pregnancy Loss. PMID:34395479
A Novel Prognostic Model for Oral Squamous Cell Carcinoma: The Functions and Prognostic Values of RNA-Binding Proteins. PMID:34395233
Deciphering the Therapeutic Mechanisms of Wuzi Ershen Decoction in Treating Oligoasthenozoospermia through the Network Pharmacology Approach. PMID:34394386
Filtering of Data-Driven Gene Regulatory Networks Using Drosophila melanogaster as a Case Study. PMID:34394179
Combination of a Sindbis-SARS-CoV-2 Spike Vaccine and αOX40 Antibody Elicits Protective Immunity Against SARS-CoV-2 Induced Disease and Potentiates Long-Term SARS-CoV-2-Specific Humoral and T-Cell Immunity. PMID:34394127
Identification of COVID-19 and Dengue Host Factor Interaction Networks Based on Integrative Bioinformatics Analyses. PMID:34394108
RGC-32 Acts as a Hub to Regulate the Transcriptomic Changes Associated With Astrocyte Development and Reactive Astrocytosis. PMID:34394104
Channeling of Carbon Flux Towards Carotenogenesis in Botryococcus braunii: A Media Engineering Perspective. PMID:34394032
Feasibility and Mechanism Analysis of Shenfu Injection in the Treatment of Idiopathic Pulmonary Fibrosis. PMID:34393772
Identification of COVID-19 prognostic markers and therapeutic targets through meta-analysis and validation of Omics data from nasopharyngeal samples. PMID:34392148
A Cross-Level Information Transmission Network for Hierarchical Omics Data Integration and Phenotype Prediction from a New Genotype. PMID:34390577
An Efficient, Nonphylogenetic Method for Detecting Genes Sharing Evolutionary Signals in Phylogenomic Data Sets. PMID:34390574
RNA Toxicity and Perturbation of rRNA Processing in Spinocerebellar Ataxia Type 2. PMID:34390268
Transcriptome-wide In Vitro Effects of Aspirin on Patient-derived Normal Colon Organoids. PMID:34389629
Multi-omics network characterization reveals novel microRNA biomarkers and mechanisms for diagnosis and subtyping of kidney transplant rejection. PMID:34389032
Compressing deep graph convolution network with multi-staged knowledge distillation. PMID:34388224
FK506 binding protein 10: a key actor of collagen crosslinking in clear cell renal cell carcinoma. PMID:34388114
Genome-Wide Identification and Characterization of the Potato IQD Family During Development and Stress. PMID:34386041
mRBioM: An Algorithm for the Identification of Potential mRNA Biomarkers From Complete Transcriptomic Profiles of Gastric Adenocarcinoma. PMID:34386038
A neurovascular-unit-on-a-chip for the evaluation of the restorative potential of stem cell therapies for ischaemic stroke. PMID:34385693
Transcriptome and Function of Novel Immunosuppressive Autoreactive Invariant Natural Killer T Cells That Are Absent in Progressive Multiple Sclerosis. PMID:34385365
Effect of black ginseng and silkworm supplementation on obesity, the transcriptome, and the gut microbiome of diet-induced overweight dogs. PMID:34381138
Cell-type and subcellular compartment-specific APEX2 proximity labeling reveals activity-dependent nuclear proteome dynamics in the striatum. PMID:34381044
Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells. PMID:34381042
Profile of the RNA in exosomes from astrocytes and microglia using deep sequencing: implications for neurodegeneration mechanisms. PMID:34380901
GraphDTI: A robust deep learning predictor of drug-target interactions from multiple heterogeneous data. PMID:34380569
Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2. PMID:34380038
Diffusion enables integration of heterogeneous data and user-driven learning in a desktop knowledge-base. PMID:34379637
A Multi-omics Longitudinal Study Reveals Alteration of the Leukocyte Activation Pathway in COVID-19 Patients. PMID:34379420
Bioinformatics analysis of the prognostic value of NEK8 and its effects on immune cell infiltration in glioma. PMID:34374193
A Master Autoantigen-ome Links Alternative Splicing, Female Predilection, and COVID-19 to Autoimmune Diseases. PMID:34373855
FcγR engagement reprograms neutrophils into antigen cross-presenting cells that elicit acquired anti-tumor immunity. PMID:34373452
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer. PMID:34373451
Identification of m6A-Related Biomarkers Associated with Prognosis of Colorectal Cancer. PMID:34373442
ELK4 promotes the development of gastric cancer by inducing M2 polarization of macrophages through regulation of the KDM5A-PJA2-KSR1 axis. PMID:34372882
Vimentin as a Cap of Invisibility: Proposed Role of Vimentin in Rabbit Hemorrhagic Disease Virus (RHDV) Infection. PMID:34372621
Evolutionary Implications of a Peroxidase with High Affinity for Cinnamyl Alcohols from Physcomitrium patens, a Non-Vascular Plant. PMID:34371679
Identification of Candidate Gene for Internode Length in Rice to Enhance Resistance to Lodging Using QTL Analysis. PMID:34371572
PPIDomainMiner: Inferring domain-domain interactions from multiple sources of protein-protein interactions. PMID:34370723
Acylglycerol Kinase-Targeted Therapies in Oncology. PMID:34368119
Analysis of Immune-Related Signatures Related to CD4+ T Cell Infiltration With Gene Co-Expression Network in Pancreatic Adenocarcinoma. PMID:34367961
The Antioxidative Role of Natural Compounds from a Green Coconut Mesocarp Undeniably Contributes to Control Diabetic Complications as Evidenced by the Associated Genes and Biochemical Indexes. PMID:34367469
The Partial Role of KLF4 and KLF5 in Gastrointestinal Tumors. PMID:34367275
Integrated Analysis of Hepatic miRNA and mRNA Expression Profiles in the Spontaneous Reversal Process of Liver Fibrosis. PMID:34367261
Multi-Level Analyses of Genome-Wide Association Study to Reveal Significant Risk Genes and Pathways in Neuromyelitis Optica Spectrum Disorder. PMID:34367251
Plant growth promoting bacteria induce anti-quorum-sensing substances in chickpea legume seedling bioassay. PMID:34366598
E2F3 drives the epithelial-to-mesenchymal transition, cell invasion, and metastasis in breast cancer. PMID:34365840
MeCP2 prevents age-associated cognitive decline via restoring synaptic plasticity in a senescence-accelerated mouse model. PMID:34363729
Characterization of Drug-Resistant Lipid-Dependent Differentially Detectable Mycobacterium tuberculosis. PMID:34362035
alfaNET: A Database of Alfalfa-Bacterial Stem Blight Protein-Protein Interactions Revealing the Molecular Features of the Disease-causing Bacteria. PMID:34361108
Gene Expression Profile of Human Mesenchymal Stromal Cells Exposed to Hypoxic and Pseudohypoxic Preconditioning-An Analysis by RNA Sequencing. PMID:34360925
SARS-CoV-2 Infected Pediatric Cerebral Cortical Neurons: Transcriptomic Analysis and Potential Role of Toll-like Receptors in Pathogenesis. PMID:34360824
Divalent Metal Transporter 1 Knock-Down Modulates IL-1β Mediated Pancreatic Beta-Cell Pro-Apoptotic Signaling Pathways through the Autophagic Machinery. PMID:34360779
Platelet-Rich Fibrin Increases BMP2 Expression in Oral Fibroblasts via Activation of TGF-β Signaling. PMID:34360701
FOS Rescues Neuronal Differentiation of Sox2-Deleted Neural Stem Cells by Genome-Wide Regulation of Common SOX2 and AP1(FOS-JUN) Target Genes. PMID:34359927
TMEM135 is a Novel Regulator of Mitochondrial Dynamics and Physiology with Implications for Human Health Conditions. PMID:34359920
Altered Cytokine Response of Human Brain Endothelial Cells after Stimulation with Malaria Patient Plasma. PMID:34359826
Synthetic Lethality Screening Highlights Colorectal Cancer Vulnerability to Concomitant Blockade of NEDD8 and EGFR Pathways. PMID:34359705
Identification of an RNA-Binding-Protein-Based Prognostic Model for Ewing Sarcoma. PMID:34359637
Integrated mRNA and miRNA transcriptome analysis provides novel insights into the molecular mechanisms underlying goose pituitary development during the embryo-to-hatchling transition. PMID:34358958
Alterations in the gut microbiota contribute to cognitive impairment induced by the ketogenic diet and hypoxia. PMID:34358434
Targeting of Protein Kinase CK2 in Acute Myeloid Leukemia Cells Using the Clinical-Grade Synthetic-Peptide CIGB-300. PMID:34356831
Exploring the Role of Endoplasmic Reticulum Stress in Hepatocellular Carcinoma through mining of the Human Protein Atlas. PMID:34356495
Unveiling the Pathogenesis of Psychiatric Disorders Using Network Models. PMID:34356117
Ciliary Signalling and Mechanotransduction in the Pathophysiology of Craniosynostosis. PMID:34356089
Expanding the MECP2 network using comparative genomics reveals potential therapeutic targets for Rett syndrome. PMID:34355696
A Comparative Transcriptome Between Anti-drug Sensitive and Resistant Candida auris in China. PMID:34354695
Identification of Hub Genes Associated with Diabetes Mellitus and Tuberculosis Using Bioinformatic Analysis. PMID:34354368
Understanding the impact of SNPs associated with autism spectrum disorder on biological pathways in the human fetal and adult cortex. PMID:34354167
Genome-wide analysis of HECT E3 ubiquitin ligase gene family in Solanum lycopersicum. PMID:34354159
Alterations in protein expression and site-specific N-glycosylation of prostate cancer tissues. PMID:34354152
"Guilt by association" is not competitive with genetic association for identifying autism risk genes. PMID:34354131
An apocrine mechanism delivers a fully immunocompetent exocrine secretion. PMID:34354130
The RNA-binding protein Puf5 contributes to buffering of mRNA upon chromatin-mediated changes in nascent transcription. PMID:34350963
Proteomic analysis to identify markers for response to neoadjuvant treatment in esophageal and gastroesophageal cancer. PMID:34350714
H2A.B is a cancer/testis factor involved in the activation of ribosome biogenesis in Hodgkin lymphoma. PMID:34350706
Comprehensive investigation of RNA-sequencing dataset reveals the hub genes and molecular mechanisms of coronavirus disease 2019 acute respiratory distress syndrome. PMID:34350693
A Network Pharmacology Approach to Investigate the Mechanism of Erjing Prescription in Type 2 Diabetes. PMID:34349832
Identification of Candidate Blood mRNA Biomarkers in Intracerebral Hemorrhage Using Integrated Microarray and Weighted Gene Co-expression Network Analysis. PMID:34349791
Statin Treatment Induced a Lipogenic Expression Hierarchical Network Centered by SREBF2 in the Liver. PMID:34349727
Network Pharmacology Prediction and Molecular Docking-Based Strategy to Discover the Potential Pharmacological Mechanism of Huai Hua San Against Ulcerative Colitis. PMID:34349502
N6-Methyladenosine Regulators Are Involved in the Progression of and Have Clinical Impact on Breast Cancer. PMID:34349094
Protein interaction landscapes revealed by advanced in vivo cross-linking-mass spectrometry. PMID:34349018
The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output. PMID:34348895
A unified framework for the integration of multiple hierarchical clusterings or networks from multi-source data. PMID:34348641
Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity. PMID:34347354
Blood DNA Methylation and Incident Coronary Heart Disease: Evidence From the Strong Heart Study. PMID:34347013
Identification of Key Candidate Genes Related to Inflammatory Osteolysis Associated with Vitamin E-Blended UHMWPE Debris of Orthopedic Implants by Integrated Bioinformatics Analysis and Experimental Confirmation. PMID:34345178
Transcriptomic landscape of blood platelets in healthy donors. PMID:34344933
Identification and integrative analysis of ACLY and related gene panels associated with immune microenvironment reveal prognostic significance in hepatocellular carcinoma. PMID:34344378
Structure-based study of immune receptors as eligible binding targets of coronavirus SARS-CoV-2 spike protein. PMID:34343818
Identification of a GrgA-Euo-HrcA Transcriptional Regulatory Network in Chlamydia. PMID:34342542
A CpG island promoter drives the CXXC5 gene expression. PMID:34341443
CENPL, ISG20L2, LSM4, MRPL3 are four novel hub genes and may serve as diagnostic and prognostic markers in breast cancer. PMID:34341433
Longitudinal stability of urinary extracellular vesicle protein patterns within and between individuals. PMID:34341426
Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding. PMID:34341383
Orientia tsutsugamushi Nucleomodulin Ank13 Exploits the RaDAR Nuclear Import Pathway To Modulate Host Cell Transcription. PMID:34340535
Identification of Key Biomarkers and Immune Infiltration in Systemic Juvenile Idiopathic Arthritis by Integrated Bioinformatic Analysis. PMID:34336925
Comparative Transcriptional Analysis of Pulmonary Arterial Hypertension Associated With Three Different Diseases. PMID:34336829
Identification of the Prognostic Signatures of Glioma With Different PTEN Status. PMID:34336645
NMU Is a Poor Prognostic Biomarker in Patients with Lung Adenocarcinoma. PMID:34336003
Identification of Hub Genes and Small Molecule Drugs Associated with Acquired Resistance to Gefitinib in Non-Small Cell Lung Cancer. PMID:34335945
Bioinformatics Analysis of the Molecular Mechanism and Potential Treatment Target of Ankylosing Spondylitis. PMID:34335866
Mangiferin Inhibits Human Lung Adenocarcinoma by Suppressing MiR-27b and MiR-92a. PMID:34335801
Comprehensive Analysis of the Value of SMYD Family Members in the Prognosis and Immune Infiltration of Malignant Digestive System Tumors. PMID:34335697
Identification of HCC-Related Genes Based on Differential Partial Correlation Network. PMID:34335688
SIRT4 and SIRT6 Serve as Novel Prognostic Biomarkers With Competitive Functions in Serous Ovarian Cancer. PMID:34335684
A Computational Exploration of the Molecular Network Associated to Neuroinflammation in Alzheimer's Disease. PMID:34335238
Sex Differences in the Ventral Tegmental Area and Nucleus Accumbens Proteome at Baseline and Following Nicotine Exposure. PMID:34335180
Aurora kinase A (AURKA) promotes the progression and imatinib resistance of advanced gastrointestinal stromal tumors. PMID:34332577
Affinity Proteomics and Deglycoproteomics Uncover Novel EDEM2 Endogenous Substrates and an Integrative ERAD Network. PMID:34332121
CellCall: integrating paired ligand-receptor and transcription factor activities for cell-cell communication. PMID:34331449
Genetic alterations and functional networks of m6A RNA methylation regulators in pancreatic cancer based on data mining. PMID:34330301
Identification of serum prognostic marker miRNAs and construction of microRNA-mRNA networks of esophageal cancer. PMID:34329340
Prognoses and genomic analyses of proteasome 26S subunit, ATPase (PSMC) family genes in clinical breast cancer. PMID:34329194
Clinical Genetic Risk Variants Inform a Functional Protein Interaction Network for Tetralogy of Fallot. PMID:34328347
Cx43 deficiency confers EMT-mediated tamoxifen resistance to breast cancer via c-Src/PI3K/Akt pathway. PMID:34326682
Single-Cell Sequencing to Identify Six Heat Shock Protein (HSP) Genes-Mediated Progression Subtypes of Clear Cell Renal Cell Carcinoma. PMID:34326662
Duzhong Fang Attenuates the POMC-Derived Neuroinflammation in Parkinsonian Mice. PMID:34326654
Glutamic acid promotes hair growth in mice. PMID:34326383
An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer. PMID:34326322
The transcriptome of rabbit conjunctiva in dry eye disease: Large-scale changes and similarity to the human dry eye. PMID:34324523
Proteomic analysis reveals dexamethasone rescues matrix breakdown but not anabolic dysregulation in a cartilage injury model. PMID:34322675
Predicting Panel of Metabolism and Immune-Related Genes for the Prognosis of Human Ovarian Cancer. PMID:34322485
Prognostic Roles of Phosphofructokinase Platelet in Clear Cell Renal Cell Carcinoma and Correlation with Immune Infiltration. PMID:34321910
Public good exploitation in natural bacterioplankton communities. PMID:34321201
Analysis of therapeutic targets and prognostic biomarkers of CXC chemokines in cervical cancer microenvironment. PMID:34321012
Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1-skewed proinflammatory immune responses. PMID:34320039
Reboot: a straightforward approach to identify genes and splicing isoforms associated with cancer patient prognosis. PMID:34316711
Associations of individual and joint expressions of ERCC6 and ERCC8 with clinicopathological parameters and prognosis of gastric cancer. PMID:34316408
The trans-omics landscape of COVID-19. PMID:34315889
A panel of miRNAs as prognostic markers for African-American patients with triple negative breast cancer. PMID:34315420
A network pharmacology approach to uncover the key ingredients in Ginkgo Folium and their anti-Alzheimer's disease mechanisms. PMID:34315132
Three decades of ASD genetics: building a foundation for neurobiological understanding and treatment. PMID:34313757
Network pharmacology and molecular docking analysis on mechanisms of Tibetan Hongjingtian (Rhodiola crenulata) in the treatment of COVID-19. PMID:34313585
Recent ultra-rare inherited variants implicate new autism candidate risk genes. PMID:34312540
Polyubiquitin gene Ubb is required for upregulation of Piwi protein level during mouse testis development. PMID:34312369
Modelling of gene loss propensity in the pangenomes of three Brassica species suggests different mechanisms between polyploids and diploids. PMID:34310022
Structural and Functional Elucidation of IF-3 Protein of Chloroflexus aurantiacus Involved in Protein Biosynthesis: An In Silico Approach. PMID:34307671
Prediction of a Potential Mechanism of Intervertebral Disc Degeneration Based on a Novel Competitive Endogenous RNA Network. PMID:34307661
Spironolactone Ameliorates Senescence and Calcification by Modulating Autophagy in Rat Tendon-Derived Stem Cells via the NF-κB/MAPK Pathway. PMID:34306308
Systematic Analysis of the Oncogenic Role of WDR62 in Human Tumors. PMID:34306258
A Combined Network Pharmacology and Molecular Docking Approach to Investigate Candidate Active Components and Multitarget Mechanisms of Hemerocallis Flowers on Antidepressant Effect. PMID:34306154
Study on HOXBs of Clear Cell Renal Cell Carcinoma and Detection of New Molecular Target. PMID:34306077
Watch Out for a Second SNP: Focus on Multi-Nucleotide Variants in Coding Regions and Rescued Stop-Gained. PMID:34306009
Omics Multi-Layers Networks Provide Novel Mechanistic and Functional Insights Into Fat Storage and Lipid Metabolism in Poultry. PMID:34306005
Deregulation of the Kallikrein Protease Family in the Salivary Glands of the Sjögren's Syndrome ERdj5 Knockout Mouse Model. PMID:34305928
Pan-cancer analysis of clinical significance and associated molecular features of glycolysis. PMID:34304708
Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia. PMID:34301992
An exploratory assessment of the applicability of direct-to-consumer genetic testing to translational research in Japan. PMID:34301328
Differential impacts of TNFα inhibitors on the transcriptome of Th cells. PMID:34301319
Long-range linkage disequilibrium in French beef cattle breeds. PMID:34301193
Enhanced Vasculogenic Capacity Induced by 5-Fluorouracil Chemoresistance in a Gastric Cancer Cell Line. PMID:34299320
Cigarette Smoke Specifically Affects Small Airway Epithelial Cell Populations and Triggers the Expansion of Inflammatory and Squamous Differentiation Associated Basal Cells. PMID:34299265
CFTR Lifecycle Map-A Systems Medicine Model of CFTR Maturation to Predict Possible Active Compound Combinations. PMID:34299207
Compatibility of Distinct Label-Free Proteomic Workflows in Absolute Quantification of Proteins Linked to the Oocyte Quality in Human Follicular Fluid. PMID:34299044
New Partners Identified by Mass Spectrometry Assay Reveal Functions of NCAM2 in Neural Cytoskeleton Organization. PMID:34299022
Proteomics of Multiple Sclerosis: Inherent Issues in Defining the Pathoetiology and Identifying (Early) Biomarkers. PMID:34298997
Pectobacterium parmentieri SCC 3193 Mutants with Altered Synthesis of Cell Surface Polysaccharides Are Resistant to N4-Like Lytic Bacteriophage ϕA38 (vB_Ppp_A38) but Express Decreased Virulence in Potato (Solanum tuberosum L.) Plants. PMID:34298965
Transcriptional Profile of Cytokines, Regulatory Mediators and TLR in Mesenchymal Stromal Cells after Inflammatory Signaling and Cell-Passaging. PMID:34298927
A Panel of rSNPs Demonstrating Allelic Asymmetry in Both ChIP-seq and RNA-seq Data and the Search for Their Phenotypic Outcomes through Analysis of DEGs. PMID:34298860
Protective effects of cannabidiol on the membrane proteins of skin keratinocytes exposed to hydrogen peroxide via participation in the proteostasis network. PMID:34298466
Single cell functional genomics reveals plasticity of subcutaneous white adipose tissue (WAT) during early postnatal development. PMID:34298199
Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang. PMID:34297769
Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease. PMID:34297416
The TOR-dependent phosphoproteome and regulation of cellular protein synthesis. PMID:34296454
Screening of hub genes and evaluation of the growth regulatory role of CD44 in metastatic prostate cancer. PMID:34296309
Identification and Exploration of Novel Macrophage M2-Related Biomarkers and Potential Therapeutic Agents in Endometriosis. PMID:34295919
Helicobacter pylori-induced protein tyrosine phosphatase receptor type C as a prognostic biomarker for gastric cancer. PMID:34295557
Identification of Potential Signatures and Their Functions for Acute Lymphoblastic Leukemia: A Study Based on the Cancer Genome Atlas. PMID:34295352
N6-Methyladenosine RNA modification in cerebrospinal fluid as a novel potential diagnostic biomarker for progressive multiple sclerosis. PMID:34294105
Comprehensive analysis of BTN3A1 in cancers: mining of omics data and validation in patient samples and cellular models. PMID:34293829
The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas. PMID:34293822
DIA-Based Proteome Profiling of Nasopharyngeal Swabs from COVID-19 Patients. PMID:34292740
Integrated Analysis of lncRNAs, mRNAs, and TFs to Identify Regulatory Networks Underlying MAP Infection in Cattle. PMID:34290737
Multiregional profiling of the brain transmembrane proteome uncovers novel regulators of depression. PMID:34290087
Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling. PMID:34288827
Exosomes in Epilepsy of Tuberous Sclerosis Complex: Carriers of Pro-Inflammatory MicroRNAs. PMID:34287356
RNA Sequencing of CD4+ T Cells in Relapsing-Remitting Multiple Sclerosis Patients at Relapse: Deciphering the Involvement of Novel genes and Pathways. PMID:34286457
Exploration of Potential Molecular Targets of Dexmedetomidine in the Intestinal Repair of Burnt Rats. PMID:34285543
Correlation between vascular endothelial growth factor pathway and immune microenvironment in head and neck squamous cell carcinoma. PMID:34284746
An integrative study of genetic variants with brain tissue expression identifies viral etiology and potential drug targets of multiple sclerosis. PMID:34284104
Structural and Functional Annotation of Napin-Like Protein from Momordica charantia to Explore its Medicinal Importance. PMID:34282529
Novel germline variant in the histone demethylase and transcription regulator KDM4C induces a multi-cancer phenotype. PMID:34281993
A novel ferroptosis-related 12-gene signature predicts clinical prognosis and reveals immune relevancy in clear cell renal cell carcinoma. PMID:34281531
BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway. PMID:34280258
Ancestry analysis indicates two different sets of essential genes in eukaryotic model species. PMID:34279742
PPI-MASS: An Interactive Web Server to Identify Protein-Protein Interactions From Mass Spectrometry-Based Proteomics Data. PMID:34277709
Identification and Validation of Hub Genes Associated With Hepatocellular Carcinoma Via Integrated Bioinformatics Analysis. PMID:34277395
Inhibition of Chitinase-3-like-1 by K284-6111 Reduces Atopic Skin Inflammation via Repressing Lactoferrin. PMID:34277112
Identification of genes associated with sudden cardiac death: a network- and pathway-based approach. PMID:34277054
Comprehensive Transcriptomic Analysis Reveals the Role of the Immune Checkpoint HLA-G Molecule in Cancers. PMID:34276642
Protein Composition of Circulating Extracellular Vesicles Immediately Changed by Particular Short Time of High-Intensity Interval Training Exercise. PMID:34276412
The CaCA superfamily genes in Saccharum: comparative analysis and their functional implications in response to biotic and abiotic stress. PMID:34275454
Influence of Maternal Lifestyle and Diet on Perinatal DNA Methylation Signatures Associated With Childhood Arterial Stiffness at 8 to 9 Years. PMID:34275334
PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis. PMID:34274450
Study on the potential active components and molecular mechanism of Xiao Huoluo Pills in the treatment of cartilage degeneration of knee osteoarthritis based on bioinformatics analysis and molecular docking technology. PMID:34273999
PODN is a prognostic biomarker and correlated with immune infiltrates in osteosarcoma. PMID:34273970
Cocaine self-administration induces sex-dependent protein expression in the nucleus accumbens. PMID:34272455
Identification of hub genes in rheumatoid arthritis through an integrated bioinformatics approach. PMID:34271942
Computational Phosphorylation Network Reconstruction: An Update on Methods and Resources. PMID:34270057
Genome-wide interrogation of transfer RNA-derived small RNAs in a mouse model of traumatic brain injury. PMID:34269214
Expression levels of chemokine (C-X-C motif) ligands CXCL1 and CXCL3 as prognostic biomarkers in rectal adenocarcinoma: evidence from Gene Expression Omnibus (GEO) analyses. PMID:34269159
Comparative Proteomic Analysis of Polarized Human THP-1 and Mouse RAW264.7 Macrophages. PMID:34267761
Dissecting Prognosis Modules and Biomarkers in Glioblastoma Based on Weighted Gene Co-Expression Network Analysis. PMID:34267555
Identification of Potential Key Genes and Regulatory Markers in Essential Thrombocythemia Through Integrated Bioinformatics Analysis and Clinical Validation. PMID:34267539
Distinct mechanisms mediate X chromosome dosage compensation in Anopheles and Drosophila. PMID:34266874
Transcriptome-based stemness indices analysis reveals platinum-based chemo-theraputic response indicators in advanced-stage serous ovarian cancer. PMID:34266348
Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer's Disease. PMID:34263425
Integrated Analysis of Microarray and RNA-Seq Data for the Identification of Hub Genes and Networks Involved in the Pancreatic Cancer. PMID:34262595
The tweety Gene Family: From Embryo to Disease. PMID:34262434
Ten-gene signature reveals the significance of clinical prognosis and immuno-correlation of osteosarcoma and study on novel skeleton inhibitors regarding MMP9. PMID:34261456
A network-biology approach for identification of key genes and pathways involved in malignant peritoneal mesothelioma. PMID:34261301
Effect of dapagliflozin on diabetic patients with cardiovascular disease via MAPK signalling pathway. PMID:34258872
PLOD2 Is a Potent Prognostic Marker and Associates with Immune Infiltration in Cervical Cancer. PMID:34258263
An Investigation of the Antigastric Cancer Effect in Tumor Microenvironment of Radix Rhei Et Rhizome: A Network Pharmacology Study. PMID:34257692
Targeting UCHL1 Induces Cell Cycle Arrest in High-Risk Multiple Myeloma with t(4;14). PMID:34257568
Identification of Potential Biomarkers From Hepatocellular Carcinoma With MT1 Deletion. PMID:34257549
Identification of Prognostic Related Genes of Tumor Microenvironment Derived From Esophageal Cancer Patients. PMID:34257539
Bioinformatics Analysis of Candidate Genes and Pathways Related to Hepatocellular Carcinoma in China: A Study Based on Public Databases. PMID:34257537
Silencing Osteopontin Expression Inhibits Proliferation, Invasion and Induce Altered Protein Expression in Melanoma Cells. PMID:34257527
Bayesian information sharing enhances detection of regulatory associations in rare cell types. PMID:34252956
DeepGraphGO: graph neural network for large-scale, multispecies protein function prediction. PMID:34252926
Screening and identification of angiogenesis-related genes as potential novel prognostic biomarkers of hepatocellular carcinoma through bioinformatics analysis. PMID:34252885
A transcriptome-wide association study to detect novel genes for volumetric bone mineral density. PMID:34252604
Modeling Immune Dynamics in Plants Using JIMENA-Package. PMID:34251626
Gastrodin Exerts Cardioprotective Action via Inhibition of Insulin-Like Growth Factor Type 2/Insulin-Like Growth Factor Type 2 Receptor Expression in Cardiac Hypertrophy. PMID:34250336
Proteomic and Biological Analysis of an In Vitro Human Endothelial System in Response to Drug Anaphylaxis. PMID:34248989
Circulating and Synovial Pentraxin-3 (PTX3) Expression Levels Correlate With Rheumatoid Arthritis Severity and Tissue Infiltration Independently of Conventional Treatments Response. PMID:34248970
Gene Expression Profiles Analyzed Using Integrating RNA Sequencing, and Microarray Reveals Increased Inflammatory Response, Proliferation, and Osteoclastogenesis in Pigmented Villonodular Synovitis. PMID:34248943
Surfaceome and Exoproteome Dynamics in Dual-Species Pseudomonas aeruginosa and Staphylococcus aureus Biofilms. PMID:34248881
Bioinformatics analysis of the role of CXC ligands in the microenvironment of head and neck tumor. PMID:34247149
DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies. PMID:34246298
High-throughput analysis of the interactions between viral proteins and host cell RNAs. PMID:34246161
Published anti-SARS-CoV-2 in vitro hits share common mechanisms of action that synergize with antivirals. PMID:34245241
Reciprocal interaction between SIRT6 and APC/C regulates genomic stability. PMID:34244565
Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer's disease by meta-analysis and adaptive boosting ensemble learning. PMID:34243793
Proximity labeling reveals non-centrosomal microtubule-organizing center components required for microtubule growth and localization. PMID:34242576
An integrative network-based approach for drug target indication expansion. PMID:34242265
Analysis of Molecular Mechanism of Erxian Decoction in Treating Osteoporosis Based on Formula Optimization Model. PMID:34239693
Study on the Molecular Mechanism of the Herbal Couple Sparganii Rhizoma-Curcumae Rhizoma in the Treatment of Lung Cancer Based on Network Pharmacology. PMID:34239587
Capivasertib restricts SARS-CoV-2 cellular entry: a potential clinical application for COVID-19. PMID:34239361
Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease. PMID:34239132
Integrative Multi-Omics Approaches in Cancer Research: From Biological Networks to Clinical Subtypes. PMID:34238766
Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel-like proteins 1 and 2. PMID:34238763
Proteomic signatures for perioperative oxygen delivery in skin after major elective surgery: mechanistic sub-study of a randomised controlled trial. PMID:34238546
Single-cell classification using graph convolutional networks. PMID:34238220
Global mapping of Salmonella enterica-host protein-protein interactions during infection. PMID:34237247
Integrated Multi-Omics Analysis of Mechanisms Underlying Yeast Ethanol Tolerance. PMID:34236875
Databases for Protein-Protein Interactions. PMID:34236665
Brain Acetyl-CoA Production and Phosphorylation of Cytoskeletal Proteins Are Targets of CYP46A1 Activity Modulation and Altered Sterol Flux. PMID:34235635
Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses. PMID:34234921
Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations. PMID:34232958
Molecular mechanism of reproductive toxicity induced by Tripterygium Wilfordii based on network pharmacology. PMID:34232166
Untangling the genetic link between type 1 and type 2 diabetes using functional genomics. PMID:34230558
SARS-CoV-2 infection in the mouse olfactory system. PMID:34230457
Palaeoproteomic analyses of dog palaeofaeces reveal a preserved dietary and host digestive proteome. PMID:34229485
Prognostic and immunological value of ATP6AP1 in breast cancer: implications for SARS-CoV-2. PMID:34228637
Identification of potential biomarkers for pathogenesis of Alzheimer's disease. PMID:34225819
Identification of differential key biomarkers in the synovial tissue between rheumatoid arthritis and osteoarthritis using bioinformatics analysis. PMID:34224029
Evaluation of a five-gene signature associated with stromal infiltration for diffuse large B-cell lymphoma. PMID:34222425
Genome Wide Prediction, Mapping and Development of Genomic Resources of Mastitis Associated Genes in Water Buffalo. PMID:34222390
CBX4 Provides an Alternate Mode of Colon Cancer Development via Potential Influences on Circadian Rhythm and Immune Infiltration. PMID:34222240
Identification of Potential ceRNA Network and Patterns of Immune Cell Infiltration in Systemic Sclerosis-Associated Interstitial Lung Disease. PMID:34222222
De Novo Mutation in Non-Tyrosine Kinase Domain of ROS1 as a Potential Predictor of Immune Checkpoint Inhibitors in Melanoma. PMID:34221982
Identification of Early Diagnostic and Prognostic Biomarkers via WGCNA in Stomach Adenocarcinoma. PMID:34221961
Integrative Characterization of Immune-relevant Genes in Hepatocellular Carcinoma. PMID:34221916
A comprehensive review of integrative pharmacology-based investigation: A paradigm shift in traditional Chinese medicine. PMID:34221858
Comprehensive Analysis of Regulatory Network for LINC00472 in Clear Cell Renal Cell Carcinoma. PMID:34221297
Investigation of the Mechanisms of Chuankezhi Injection in the Treatment of Asthma Based on the Network Pharmacology Approach. PMID:34221070
Individuality in the Immune Repertoire and Induced Response of the Sponge Halichondria panicea. PMID:34220847
Response to Oxidative Burst-Induced Hypoxia Is Associated With Macrophage Inflammatory Profiles as Revealed by Cellular Genome-Wide Association. PMID:34220845
Mapping Salivary Proteases in Sjögren's Syndrome Patients Reveals Overexpression of Dipeptidyl Peptidase-4/CD26. PMID:34220840
Molecular Characterization and Survive Abilities of Salmonella Heidelberg Strains of Poultry Origin in Brazil. PMID:34220757
Microbiome diversity and host immune functions influence survivorship of sponge holobionts under future ocean conditions. PMID:34218251
A radiosensitizer, gallotannin-rich extract from Bouea macrophylla seeds, inhibits radiation-induced epithelial-mesenchymal transition in breast cancer cells. PMID:34217266
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis. PMID:34215846
The pattern of gene copy number alteration (CNAs) in hepatocellular carcinoma: an in silico analysis. PMID:34215297
Comprehensive analysis of diabetic nephropathy expression profile based on weighted gene co-expression network analysis algorithm. PMID:34215202
ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions. PMID:34214142
Genome-Wide Investigation of N6-Methyladenosine Regulatory Genes and Their Roles in Tea (Camellia sinensis) Leaves During Withering Process. PMID:34211493
Genetic drivers of m6A methylation in human brain, lung, heart and muscle. PMID:34211177
Machine learning compensates fold-change method and highlights oxidative phosphorylation in the brain transcriptome of Alzheimer's disease. PMID:34211065
The Serine Protease Homolog, Scarface, Is Sensitive to Nutrient Availability and Modulates the Development of the Drosophila Blood-Brain Barrier. PMID:34210781
Toward a Coronavirus Knowledge Graph. PMID:34209818
Withaferin A Triggers Apoptosis and DNA Damage in Bladder Cancer J82 Cells through Oxidative Stress. PMID:34209212
Site-Specific and Common Prostate Cancer Metastasis Genes as Suggested by Meta-Analysis of Gene Expression Data. PMID:34209195
Dynamic Adaptive Response of Pseudomonas aeruginosa to Clindamycin/Rifampicin-Impregnated Catheters. PMID:34206280
Genome-Wide Associations for Microscopic Differential Somatic Cell Count and Specific Mastitis Pathogens in Holstein Cows in Compost-Bedded Pack and Cubicle Farming Systems. PMID:34205623
Comprehensive Analysis of SFRP Family Members Prognostic Value and Immune Infiltration in Gastric Cancer. PMID:34205081
Dysregulated Expression of Arterial MicroRNAs and Their Target Gene Networks in Temporal Arteries of Treatment-Naïve Patients with Giant Cell Arteritis. PMID:34204585
PI3K and MAPK Pathways as Targets for Combination with the Pan-HER Irreversible Inhibitor Neratinib in HER2-Positive Breast Cancer and TNBC by Kinome RNAi Screening. PMID:34203351
Simulated Microgravity Effects on Human Adenocarcinoma Alveolar Epithelial Cells: Characterization of Morphological, Functional, and Epigenetic Parameters. PMID:34203322
Global Alternative Splicing Defects in Human Breast Cancer Cells. PMID:34202984
Early Renoprotective Effect of Ruxolitinib in a Rat Model of Diabetic Nephropathy. PMID:34202668
Global Proteomic Profiling of Pediatric AML: A Pilot Study. PMID:34202615
mRNA-miRNA-lncRNA Regulatory Network in Nonalcoholic Fatty Liver Disease. PMID:34202571
Design, Synthesis, Biological Evaluation and Silico Prediction of Novel Sinomenine Derivatives. PMID:34200341
High SGO2 Expression Predicts Poor Overall Survival: A Potential Therapeutic Target for Hepatocellular Carcinoma. PMID:34200261
HGF/c-Met Inhibition as Adjuvant Therapy Improves Outcomes in an Orthotopic Mouse Model of Pancreatic Cancer. PMID:34199452
A Transcriptomic Approach to the Metabolism of Tetrapyrrolic Photosensitizers in a Marine Annelid. PMID:34198975
Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms. PMID:34197603
Predictive Study of the Active Ingredients and Potential Targets of Codonopsis pilosula for the Treatment of Osteosarcoma via Network Pharmacology. PMID:34194515
Exploration of the Key Proteins in the Normal-Adenoma-Carcinoma Sequence of Colorectal Cancer Evolution Using In-Depth Quantitative Proteomics. PMID:34194496
Two Arabidopsis Homologs of Human Lysine-Specific Demethylase Function in Epigenetic Regulation of Plant Defense Responses. PMID:34194459
Age-dependent shift in the de novo proteome accompanies pathogenesis in an Alzheimer's disease mouse model. PMID:34193971
Identification of SARS-CoV-2-induced pathways reveals drug repurposing strategies. PMID:34193418
Innate immune response analysis in COVID-19 and kawasaki disease reveals MIS-C predictors. PMID:34193364
Down-regulation of BCL2L13 renders poor prognosis in clear cell and papillary renal cell carcinoma. PMID:34193180
Light-induced changes in the suprachiasmatic nucleus transcriptome regulated by the ERK/MAPK pathway. PMID:34191798
Prediction of Human-Plasmodium vivax Protein Associations From Heterogeneous Network Structures Based on Machine-Learning Approach. PMID:34188457
Constrained G4 structures unveil topology specificity of known and new G4 binding proteins. PMID:34188089
Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs. PMID:34186244
Genetic program activity delineates risk, relapse, and therapy responsiveness in multiple myeloma. PMID:34183722
CircRNA_100290 promotes GC cell proliferation and invasion via the miR-29b-3p/ITGA11 axis and is regulated by EIF4A3. PMID:34182990
CROssBAR: comprehensive resource of biomedical relations with knowledge graph representations. PMID:34181736
Potential therapeutic target genes for systemic lupus erythematosus: a bioinformatics analysis. PMID:34180358
Integrated bioinformatics identifies the dysregulation induced by aberrant gene methylation in colorectal carcinoma. PMID:34179314
Gene set enrichment analysis of PPAR-γ regulators from Murraya odorata Blanco. PMID:34178844
Integrative Multi-Omics Analysis of Identified NUF2 as a Candidate Oncogene Correlates With Poor Prognosis and Immune Infiltration in Non-Small Cell Lung Cancer. PMID:34178642
Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway. PMID:34178027
Identification of the Signature Associated With m6A RNA Methylation Regulators and m6A-Related Genes and Construction of the Risk Score for Prognostication in Early-Stage Lung Adenocarcinoma. PMID:34178026
In Silico and In Vivo Studies on the Mechanisms of Chinese Medicine Formula (Gegen Qinlian Decoction) in the Treatment of Ulcerative Colitis. PMID:34177580
Glycyrrhizic Acid for COVID-19: Findings of Targeting Pivotal Inflammatory Pathways Triggered by SARS-CoV-2. PMID:34177566
Gene signatures and potential therapeutic targets of Middle East respiratory syndrome coronavirus (MERS-CoV)-infected human lung adenocarcinoma epithelial cells. PMID:34176764
An integrative transcriptome study reveals Ddit4/Redd1 as a key regulator of cancer cachexia in rodent models. PMID:34175899
Identification of differentially expressed genes-related prognostic risk model for survival prediction in breast carcinoma patients. PMID:34175839
Bioinformatics analysis of differentially expressed genes and pathways in the development of cervical cancer. PMID:34174849
Construction of lncRNA-Mediated ceRNA Network for Investigating Immune Pathogenesis of Ischemic Stroke. PMID:34173933
Whole-exome sequencing reveals a novel homozygous mutation in the COQ8B gene associated with nephrotic syndrome. PMID:34172776
Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function. PMID:34172723
The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance. PMID:34171263
Gene Expression Profiles of Human Cerebral Organoids Identify PPAR Pathway and PKM2 as Key Markers for Oxygen-Glucose Deprivation and Reoxygenation. PMID:34168538
Integrated lipidomics and proteomics reveal cardiolipin alterations, upregulation of HADHA and long chain fatty acids in pancreatic cancer stem cells. PMID:34168259
Low-density lipoprotein receptor-related protein 1 (LRP1) is a novel receptor for apolipoprotein A4 (APOA4) in adipose tissue. PMID:34168225
Evolutionary analysis and functional characterization of SiBRI1 as a Brassinosteroid receptor gene in foxtail millet. PMID:34167462
Endosomal cAMP production broadly impacts the cellular phosphoproteome. PMID:34166681
HMGB1 coordinates SASP-related chromatin folding and RNA homeostasis on the path to senescence. PMID:34166567
Using Multilayer Heterogeneous Networks to Infer Functions of Phosphorylated Sites. PMID:34164982
Identification and Validation of a Novel Prognosis Prediction Model in Adrenocortical Carcinoma by Integrative Bioinformatics Analysis, Statistics, and Machine Learning. PMID:34164395
Ultrasensitive single-cell proteomics workflow identifies >1000 protein groups per mammalian cell. PMID:34163866
Elevated TYROBP expression predicts poor prognosis and high tumor immune infiltration in patients with low-grade glioma. PMID:34162355
Pivotal factors associated with the immunosuppressive tumor microenvironment and melanoma metastasis. PMID:34159752
mPPI: a database extension to visualize structural interactome in a one-to-many manner. PMID:34156447
Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence. PMID:34156290
The DNA Sensor IFIX Drives Proteome Alterations To Mobilize Nuclear and Cytoplasmic Antiviral Responses, with Its Acetylation Acting as a Localization Toggle. PMID:34156286
Quantitative mapping of human hair greying and reversal in relation to life stress. PMID:34155974
Disentangling transcriptional responses in plant defense against arthropod herbivores. PMID:34155286
The barrier functions of crude cervical mucus plugs against HIV-1 infection in the context of cell-free and cell-to-cell transmission. PMID:34155151
RTP4 is a novel prognosis-related hub gene in cutaneous melanoma. PMID:34154655
High-throughput microfluidic 3D biomimetic model enabling quantitative description of the human breast tumor microenvironment. PMID:34153511
A Systems-Based Key Innovation-Driven Approach Infers Co-option of Jaw Developmental Programs During Cancer Progression. PMID:34150777
MicroRNA profiles in five pairs of early gastric cancer tissues and adjacent non-cancerous tissues. PMID:34149906
Molecular Traits and Functional Analysis of the CLAVATA3/Endosperm Surrounding Region-Related Small Signaling Peptides in Three Species of Gossypium Genus. PMID:34149772
Reflections on the genetics-first approach to advancements in molecular genetic and neurobiological research on neurodevelopmental disorders. PMID:34148555
Identification of sixteen novel candidate genes for late onset Parkinson's disease. PMID:34148545
Damage-Net: A program for DNA repair meta-analysis identifies a network of novel repair genes that facilitate cancer evolution. PMID:34147942
[Exploratory screening of potential pan-cancer biomarkers based on The Cancer Genome Atlas database]. PMID:34145869
Vaccinia virus hijacks ESCRT-mediated multivesicular body formation for virus egress. PMID:34145027
Primary cilia are required for the persistence of memory and stabilization of perineuronal nets. PMID:34142063
Proteomic Characterization of Cytoplasmic Lipid Droplets in Human Metastatic Breast Cancer Cells. PMID:34141606
Identification of Potential Key Genes Involved in the Carotid Atherosclerosis. PMID:34140767
Spatial and cell type transcriptional landscape of human cerebellar development. PMID:34140698
DCBLD1 is associated with the integrin signaling pathway and has prognostic value in non-small cell lung and invasive breast carcinoma. PMID:34140574
Analysis of the transcriptome of bovine endometrial cells isolated by laser micro-dissection (2): impacts of post-partum negative energy balance on stromal, glandular and luminal epithelial cells. PMID:34139988
Mapping the multiscale structure of biological systems. PMID:34139169
Endothelial SOCS3 maintains homeostasis and promotes survival in endotoxemic mice. PMID:34138760
Hearing Sensitivity of Primates: Recurrent and Episodic Positive Selection in Hair Cells and Stereocilia Protein-Coding Genes. PMID:34137817
Glutamine regulates ovarian cancer cell migration and invasion through ETS1. PMID:34136678
Identification of Genes Related to Immune Infiltration in the Tumor Microenvironment of Cutaneous Melanoma. PMID:34136377
Prognosis and Characterization of Immune Microenvironment in Acute Myeloid Leukemia Through Identification of an Autophagy-Related Signature. PMID:34135913
Proteomic analysis of chicken bone marrow-derived dendritic cells in response to an inactivated IBV + NDV poultry vaccine. PMID:34135356
Pan-cancer analysis reveals an immunological role and prognostic potential of PXN in human cancer. PMID:34135128
Plasma Proteomics of Renal Function: A Trans-ethnic Meta-analysis and Mendelian Randomization Study. PMID:34135082
Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes. PMID:34131782
Convergent and distributed effects of the 3q29 deletion on the human neural transcriptome. PMID:34131099
Absent in melanoma 1-like (AIM1L) serves as a novel candidate for overall survival in hepatocellular carcinoma. PMID:34130591
Genome-wide CRISPR screen identifies protein pathways modulating tau protein levels in neurons. PMID:34127790
A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study. PMID:34126933
The expression and clinical prognostic value of protein phosphatase 1 catalytic subunit beta in pancreatic cancer. PMID:34125004
Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes. PMID:34124712
Essential Role of CFAP53 in Sperm Flagellum Biogenesis. PMID:34124066
Targeting Pyrimidine Metabolism in the Era of Precision Cancer Medicine. PMID:34123854
Comprehensive Analysis of GLUT1 Immune Infiltrates and ceRNA Network in Human Esophageal Carcinoma. PMID:34123828
Identification METTL18 as a Potential Prognosis Biomarker and Associated With Immune Infiltrates in Hepatocellular Carcinoma. PMID:34123827
Bioinformatics, Molecular Docking and Experiments In Vitro Analyze the Prognostic Value of CXC Chemokines in Breast Cancer. PMID:34123826
Identification of potential gene signatures associated with osteosarcoma by integrated bioinformatics analysis. PMID:34123594
Association of Extracellular Signal-Regulated Kinase Genes With Myopia: A Longitudinal Study of Chinese Children. PMID:34122509
Proteomic Analysis of Humoral Immune Components in Bronchoalveolar Lavage of Patients Infected or Colonized by Aspergillus fumigatus. PMID:34122441
Network Pharmacology-Based Validation of the Efficacy of Huiyangjiuji Decoction in the Treatment of Experimental Colitis. PMID:34122086
Genome-wide characterization, evolution, and expression profiling of FBA gene family in response to light treatments and abiotic stress in Nicotiana tabacum. PMID:34120568
Metabolic alterations mediated by STAT3 promotes drug persistence in CML. PMID:34120146
Candidate gene screening for lipid deposition using combined transcriptomic and proteomic data from Nanyang black pigs. PMID:34118873
Identification of key genes in the tumor microenvironment of lung adenocarcinoma. PMID:34117948
Reliable identification of protein-protein interactions by crosslinking mass spectrometry. PMID:34117231
Screening and identification of Theileria annulata subtelomere-encoded variable secreted protein-950454 (SVSP454) interacting proteins from bovine B cells. PMID:34116718
Mass spectrometry and machine learning for the accurate diagnosis of benzylpenicillin and multidrug resistance of Staphylococcus aureus in bovine mastitis. PMID:34115749
Exploring polyps to colon carcinoma voyage: can blocking the crossroad halt the sequence? PMID:34115239
Measuring pathway database coverage of the phosphoproteome. PMID:34113485
Whole-Exome Sequencing Reveals a Rare Variant of OTOF Gene Causing Congenital Non-syndromic Hearing Loss Among Large Muslim Families Favoring Consanguinity. PMID:34113375
Integrated proteomic and transcriptomic profiling identifies aberrant gene and protein expression in the sarcomere, mitochondrial complex I, and the extracellular matrix in Warmblood horses with myofibrillar myopathy. PMID:34112090
A meta-analysis of transcriptomic profiles of Huntington's disease patients. PMID:34111223
cAMP-Dependent Signaling Pathways as Potential Targets for Inhibition of Plasmodium falciparum Blood Stages. PMID:34108954
Colonisation dynamics of Listeria monocytogenes strains isolated from food production environments. PMID:34108547
The derepression of transposable elements in lung cells is associated with the inflammatory response and gene activation in idiopathic pulmonary fibrosis. PMID:34108012
ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes. PMID:34107900
Genome-wide association analysis of adaptation to oxygen stress in Nile tilapia (Oreochromis niloticus). PMID:34107887
A patient-based medaka alg2 mutant as a model for hypo-N-glycosylation. PMID:34106226
Investigating the active compounds and mechanism of HuaShi XuanFei formula for prevention and treatment of COVID-19 based on network pharmacology and molecular docking analysis. PMID:34105049
Identification of Differentially Expressed circRNAs, miRNAs, and Genes in Patients Associated with Cartilaginous Endplate Degeneration. PMID:34104646
Identification of Diagnostic CpG Signatures in Patients with Gestational Diabetes Mellitus via Epigenome-Wide Association Study Integrated with Machine Learning. PMID:34104645
Identification of an Alveolar Macrophage-Related Core Gene Set in Acute Respiratory Distress Syndrome. PMID:34103966
Integration of population and functional genomics to understand mechanisms of artemisinin resistance in Plasmodium falciparum. PMID:34102588
A protected complex of biofactors and antioxidants improved growth performance and modulated the immunometabolic phenotype of broiler chickens undergoing early life stress. PMID:34102483
Garcinia cambogia attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression. PMID:34101546
Presenilin mutations and their impact on neuronal differentiation in Alzheimer's disease. PMID:34100423
Two RmlC homologs catalyze dTDP-4-keto-6-deoxy-D-glucose epimerization in Pseudomonas putida KT2440. PMID:34099824
Contribution of genetic ancestry and polygenic risk score in meeting vitamin B12 needs in healthy Brazilian children and adolescents. PMID:34099811
Multi-omics analysis reveals the interaction between the complement system and the coagulation cascade in the development of endometriosis. PMID:34099740
Characterization of terminal-ileal and colonic Crohn's disease in treatment-naïve paediatric patients based on transcriptomic profile using logistic regression. PMID:34098982
Association between RAD51, XRCC2 and XRCC3 gene polymorphisms and risk of ovarian cancer: a case control and an in silico study. PMID:34097201
Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis. PMID:34096637
Therapeutic Targeting of Repurposed Anticancer Drugs in Alzheimer's Disease: Using the Multiomics Approach. PMID:34095679
Phosphorylation in Novel Mitochondrial Creatine Kinase Tyrosine Residues Render Cardioprotection against Hypoxia/Reoxygenation Injury. PMID:34095014
Immune-Related Gene SERPINE1 Is a Novel Biomarker for Diffuse Lower-Grade Gliomas via Large-Scale Analysis. PMID:34094933
Determination of the glycoprotein specificity of lectins on cell membranes through oxidative proteomics. PMID:34094216
The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity. PMID:34093866
High Expression of RhoBTB3 Predicts Favorable Chemothrapy Outcomes in non-M3 Acute Myeloid Leukemia. PMID:34093823
Comprehensive evaluation of microRNA-10b in digestive system cancers reveals prognostic implication and signaling pathways associated with tumor progression. PMID:34093806
Heterogeneity Analysis of Esophageal Squamous Cell Carcinoma in Cell Lines, Tumor Tissues and Patient-Derived Xenografts. PMID:34093800
High SEC61G expression predicts poor prognosis in patients with Head and Neck Squamous Cell Carcinomas. PMID:34093796
A Sight on Single-Cell Transcriptomics in Plants Through the Prism of Cell-Based Computational Modeling Approaches: Benefits and Challenges for Data Analysis. PMID:34093652
Development of an Immune-Related Prognostic Index Associated With Glioblastoma. PMID:34093386
PIGNON: a protein-protein interaction-guided functional enrichment analysis for quantitative proteomics. PMID:34088263
Integrated analysis of ceRNA network in hepatocellular carcinoma using bioinformatics analysis. PMID:34087888
Identification and construction of lncRNA-associated ceRNA network in diabetic kidney disease. PMID:34087849
Reciprocal priming between receptor tyrosine kinases at recycling endosomes orchestrates cellular signalling outputs. PMID:34086370
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes. PMID:34084287
Does Oral Apigenin Have Real Potential for a Therapeutic Effect in the Context of Human Gastrointestinal and Other Cancers? PMID:34084146
Transcriptomic landscape of early age onset of colorectal cancer identifies novel genes and pathways in Indian CRC patients. PMID:34083590
Multidimensional study of cell division cycle-associated proteins with prognostic value in gastric carcinoma. PMID:34082692
Identification and assessment of PLK1/2/3/4 in lung adenocarcinoma and lung squamous cell carcinoma: Evidence from methylation profile. PMID:34080290
Potential Impact of ALKBH5 and YTHDF1 on Tumor Immunity in Colon Adenocarcinoma. PMID:34079761
Positive Selection in Gene Regulatory Factors Suggests Adaptive Pleiotropic Changes During Human Evolution. PMID:34079582
Specific N-cadherin-dependent pathways drive human breast cancer dormancy in bone marrow. PMID:34078741
Parkinson mice show functional and molecular changes in the gut long before motoric disease onset. PMID:34078425
PIKE-R2P: Protein-protein interaction network-based knowledge embedding with graph neural network for single-cell RNA to protein prediction. PMID:34078261
Identifying the molecular targets and mechanisms of xuebijing injection for the treatment of COVID-19 via network parmacology and molecular docking. PMID:34077310
Mass Spectrometric Analysis of Urine from COVID-19 Patients for Detection of SARS-CoV-2 Viral Antigen and to Study Host Response. PMID:34077217
Mantis: flexible and consensus-driven genome annotation. PMID:34076241
Mechnetor: a web server for exploring protein mechanism and the functional context of genetic variants. PMID:34076240
Combination of a Sindbis-SARS-CoV-2 spike vaccine and αOX40 antibody elicits protective immunity against SARS-CoV-2 induced disease and potentiates long-term SARS-CoV-2-specific humoral and T-cell immunity. PMID:34075383
The dysregulated Pink1- Drosophila mitochondrial proteome is partially corrected with exercise. PMID:34074800
Age-Related Alterations in the Testicular Proteome of a Non-Human Primate. PMID:34074003
Proteomic Analysis of Zeb1 Interactome in Breast Carcinoma Cells. PMID:34074001
A Novel Method for Creating a Synthetic L-DOPA Proteome and In Vitro Evidence of Incorporation. PMID:34073856
Learning from Embryogenesis-A Comparative Expression Analysis in Melanoblast Differentiation and Tumorigenesis Reveals miRNAs Driving Melanoma Development. PMID:34073664
Genome Evolutionary Dynamics Meets Functional Genomics: A Case Story on the Identification of SLC25A44. PMID:34073512
Continuous Inflammatory Stimulation Leads via Metabolic Plasticity to a Prometastatic Phenotype in Triple-Negative Breast Cancer Cells. PMID:34072893
Computational Study on Temperature Driven Structure-Function Relationship of Polysaccharide Producing Bacterial Glycosyl Transferase Enzyme. PMID:34071348
Cell Wall Proteome Profiling of a Candida albicans Fluconazole-Resistant Strain from a Lebanese Hospital Patient Using Tandem Mass Spectrometry-A Pilot Study. PMID:34071222
Bone Diagenesis in Short Timescales: Insights from an Exploratory Proteomic Analysis. PMID:34071025
Deficits in Prenatal Serine Biosynthesis Underlie the Mitochondrial Dysfunction Associated with the Autism-Linked FMR1 Gene. PMID:34070950
Syndecan-1 Depletion Has a Differential Impact on Hyaluronic Acid Metabolism and Tumor Cell Behavior in Luminal and Triple-Negative Breast Cancer Cells. PMID:34070901
Dysregulation of the Acrosome Formation Network by 8-oxoguanine (8-oxoG) in Infertile Sperm: A Case Report with Advanced Techniques. PMID:34070710
MicroRNA Profiles of Maternal and Neonatal Endothelial Progenitor Cells in Preeclampsia. PMID:34070163
Genome-Wide Identification and Analysis of the APETALA2 (AP2) Transcription Factor in Dendrobium officinale. PMID:34069261
Immunomodulatory Effects of Vitamin D Supplementation in a Deficient Population. PMID:34068701
Genome-Wide Identification of Candidate Genes for Milk Production Traits in Korean Holstein Cattle. PMID:34068321
Kallikrein-11, in Association with Coiled-Coil Domain Containing 25, as a Potential Prognostic Marker for Cholangiocarcinoma with Lymph Node Metastasis. PMID:34067437
Identification of Critical Genes and Signaling Pathways in Human Monocytes Following High-Intensity Exercise. PMID:34067297
Claudin-Low Breast Cancer Inflammatory Signatures Support Polarization of M1-Like Macrophages with Protumoral Activity. PMID:34067089
Targeting the Mild-Hypoxia Driving Force for Metabolic and Muscle Transcriptional Reprogramming of Gilthead Sea Bream (Sparus aurata) Juveniles. PMID:34066667
Western Diet Induced Remodelling of the Tongue Proteome. PMID:34066295
Syndecan-1 Promotes Angiogenesis in Triple-Negative Breast Cancer through the Prognostically Relevant Tissue Factor Pathway and Additional Angiogenic Routes. PMID:34066023
Molecular Pathways Associated with Kallikrein 6 Overexpression in Colorectal Cancer. PMID:34065672
Do Autism Spectrum and Autoimmune Disorders Share Predisposition Gene Signature Due to mTOR Signaling Pathway Controlling Expression? PMID:34065644
Environmental Conditions Modulate the Transcriptomic Response of Both Caulobacter crescentus Morphotypes to Cu Stress. PMID:34064119
Altered Expression of Candidate Genes in Mayer-Rokitansky-Küster-Hauser Syndrome May Influence Vaginal Keratinocytes Biology: A Focus on Protein Kinase X. PMID:34063745
A Proteomic Approach for Systematic Mapping of Substrates of Human Deubiquitinating Enzymes. PMID:34063716
Protein Kinase C Activation Drives a Differentiation Program in an Oligodendroglial Precursor Model through the Modulation of Specific Biological Networks. PMID:34063504
Effects of Three-Month Administration of High-Saturated Fat Diet and High-Polyunsaturated Fat Diets with Different Linoleic Acid (LA, C18:2n-6) to α-Linolenic Acid (ALA, C18:3n-3) Ratio on the Mouse Liver Proteome. PMID:34063343
Characterization of the RNA-Binding Protein TcSgn1 in Trypanosoma cruzi. PMID:34063193
Death Processes in Bovine Theca and Granulosa Cells Modelled and Analysed Using a Systems Biology Approach. PMID:34063056
COL12A1 Single Nucleotide Polymorphisms rs240736 and rs970547 Are Not Associated with Temporomandibular Joint Disc Displacement without Reduction. PMID:34062975
Network Pharmacology and Molecular Docking Combined to Analyze the Molecular and Pharmacological Mechanism of Pinellia ternata in the Treatment of Hypertension. PMID:34062719
Proteomics analysis reveals the effect of 1α,25(OH)2VD3-glycosides on development of early testes in piglets. PMID:34059707
MMP8 increases tongue carcinoma cell-cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5. PMID:34059618
MAPK14 over-expression is a transcriptomic feature of polycythemia vera and correlates with adverse clinical outcomes. PMID:34059095
Quercetin for COVID-19 and DENGUE co-infection: a potential therapeutic strategy of targeting critical host signal pathways triggered by SARS-CoV-2 and DENV. PMID:34058750
Similarities and Differences in Gene Expression Networks Between the Breast Cancer Cell Line Michigan Cancer Foundation-7 and Invasive Human Breast Cancer Tissues. PMID:34056582
Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons. PMID:34056454
Integrated DNA Methylation and Gene Expression Analysis Identified S100A8 and S100A9 in the Pathogenesis of Obesity. PMID:34055926
Liver proteome alterations in psychologically distressed rats and a nootropic drug. PMID:34055494
Effective Material Basis and Mechanism Analysis of Compound Banmao Capsule against Tumors Using Integrative Network Pharmacology and Molecular Docking. PMID:34055017
Systemic Bioinformatic Analyses of Nuclear-Encoded Mitochondrial Genes in Hypertrophic Cardiomyopathy. PMID:34054926
New Insights Into Structure and Function of TIFY Genes in Zea mays and Solanum lycopersicum: A Genome-Wide Comprehensive Analysis. PMID:34054921
Medicinal Plant Leaf Extract From Sage and Lemon Verbena Promotes Intestinal Immunity and Barrier Function in Gilthead Seabream (Sparus aurata). PMID:34054843
Comprehensive Analysis of PD-L1 Expression, Immune Infiltrates, and m6A RNA Methylation Regulators in Esophageal Squamous Cell Carcinoma. PMID:34054840
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation. PMID:34054546
Investigation of the Multi-Target Mechanism of Guanxin-Shutong Capsule in Cerebrovascular Diseases: A Systems Pharmacology and Experimental Assessment. PMID:34054530
Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation. PMID:34051074
ncFANs v2.0: an integrative platform for functional annotation of non-coding RNAs. PMID:34050762
A multiple network-based bioinformatics pipeline for the study of molecular mechanisms in oncological diseases for personalized medicine. PMID:34050359
Retention time prediction using neural networks increases identifications in crosslinking mass spectrometry. PMID:34050149
Dysregulation of post-transcriptional modification by copy number variable microRNAs in schizophrenia with enhanced glycation stress. PMID:34050135
Lipid Pathway Databases with a Focus on Algae. PMID:34047993
Large-scale identification of protein histidine methylation in human cells. PMID:34046594
High glucose treatment promotes extracellular matrix proteome remodeling in Mller glial cells. PMID:34046254
Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis. PMID:34046031
Integrated Strategy of Network Pharmacological Prediction and Experimental Validation Elucidate Possible Mechanism of Bu-Yang Herbs in Treating Postmenopausal Osteoporosis via ESR1. PMID:34045964
Toxoplasma gondii secreted effectors co-opt host repressor complexes to inhibit necroptosis. PMID:34043960
Comparative proteomic analysis to annotate the structural and functional association of the hypothetical proteins of S. maltophilia k279a and predict potential T and B cell targets for vaccination. PMID:34043709
The potential roles of lncRNAs DUXAP8, LINC00963, and FOXD2-AS1 in luminal breast cancer based on expression analysis and bioinformatic approaches. PMID:34043149
Transcriptional signatures of human peripheral blood mononuclear cells can identify the risk of tuberculosis progression from latent infection among individuals with silicosis. PMID:34042560
Proteome dataset of chili pepper plant (Capsicum frutescens) infested by broad mite (Polyphagotarsonemus latus). PMID:34041315
Identification of diagnostic genes and vital microRNAs involved in rheumatoid arthritis: based on data mining and experimental verification. PMID:34040897
Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions. PMID:34040168
Genomic insights into the pathogenesis of Epstein-Barr virus-associated diffuse large B-cell lymphoma by whole-genome and targeted amplicon sequencing. PMID:34039950
A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver. PMID:34038707
Aviator: a web service for monitoring the availability of web services. PMID:34038559
NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development. PMID:34037780
A Study to Decipher the Potential Effects of Butylphthalide against Central Nervous System Diseases Based on Network Pharmacology and Molecular Docking Integration Strategy. PMID:34035826
An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs. PMID:34033851
Exploration of glutathione reductase for abiotic stress response in bread wheat (Triticum aestivum L.). PMID:34032897
Supraphysiological estradiol promotes human T follicular helper cell differentiation and favours humoural immunity during in vitro fertilization. PMID:34032001
Transcriptomic and metabolomic characterization of post-hatch metabolic reprogramming during hepatic development in the chicken. PMID:34030631
driveR: a novel method for prioritizing cancer driver genes using somatic genomics data. PMID:34030627
Arginine methylation of SARS-Cov-2 nucleocapsid protein regulates RNA binding, its ability to suppress stress granule formation, and viral replication. PMID:34029587
Multiomic Big Data Analysis Challenges: Increasing Confidence in the Interpretation of Artificial Intelligence Assessments. PMID:34029068
Identification of differentially expressed genes in diabetic kidney disease by RNA-Seq analysis of venous blood platelets. PMID:34029013
Multiple cellular compartments engagement in Nicotiana benthamiana-peanut stunt virus-satRNA interactions revealed by systems biology approach. PMID:34028582
Identification of Key Genes With Differential Correlations in Lung Adenocarcinoma. PMID:34026765
A New Oxaliplatin Resistance-Related Gene Signature With Strong Predicting Ability in Colon Cancer Identified by Comprehensive Profiling. PMID:34026619
PAP90, a novel rice protein plays a critical role in regulation of D1 protein stability of PSII. PMID:34026296
Computational modeling and bioinformatic analyses of functional mutations in drug target genes in Mycobacterium tuberculosis. PMID:34025934
Identification of key genes in calcific aortic valve disease via weighted gene co-expression network analysis. PMID:34020624
Hsa_circ_0000301 facilitates the progression of cervical cancer by targeting miR-1228-3p/IRF4 Axis. PMID:34020619
Unraveling the molecular crosstalk between Atherosclerosis and COVID-19 comorbidity. PMID:34020127
KEA3: improved kinase enrichment analysis via data integration. PMID:34019655
Age-related telomere attrition causes aberrant gene expression in sub-telomeric regions. PMID:34018656
Scaffold compound L971 exhibits anti-inflammatory activities through inhibition of JAK/STAT and NFκB signalling pathways. PMID:34018320
The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape. PMID:34017122
Whole transcriptome RNA-seq reveals key regulatory factors involved in type 2 diabetes pathology in peripheral fat of Asian Indians. PMID:34017037
Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure. PMID:34016951
Integrated bioinformatic analysis reveals the underlying molecular mechanism of and potential drugs for pulmonary arterial hypertension. PMID:34016786
Quantitative Analysis of Tyrosine Phosphorylation from FFPE Tissues Reveals Patient-Specific Signaling Networks. PMID:34016623
TMT-based proteomic and bioinformatic analyses of human granulosa cells from obese and normal-weight female subjects. PMID:34016141
Elevated expression of LPCAT1 predicts a poor prognosis and is correlated with the tumour microenvironment in endometrial cancer. PMID:34016103
Metabolic syndrome and the plasma proteome: from association to causation. PMID:34016094
Prognostic and clinicopathological insights of phosphodiesterase 9A gene as novel biomarker in human colorectal cancer. PMID:34016083
A computational approach for detecting physiological homogeneity in the midst of genetic heterogeneity. PMID:34015270
Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke. PMID:34015256
Utilizing graph machine learning within drug discovery and development. PMID:34013350
Host pharmacogenetic factors that may affect liver neoplasm incidence upon using direct-acting antivirals for treating hepatitis C infection. PMID:34013078
Identification of gene signatures and potential therapeutic targets for acquired chemotherapy resistance in gastric cancer patients. PMID:34012635
Helicase-like transcription factor-deletion from the tumor microenvironment in a cell line-derived xenograft model of colorectal cancer reprogrammed the human transcriptome-S-nitroso-proteome to promote inflammation and redirect metastasis. PMID:34010296
Transcriptome Analyses Implicate Endogenous Retroviruses Involved in the Host Antiviral Immune System through the Interferon Pathway. PMID:34009516
JunB is a key regulator of multiple myeloma bone marrow angiogenesis. PMID:34007044
Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes. PMID:34007041
From multi-omics integration towards novel genomic interaction networks to identify key cancer cell line characteristics. PMID:34006939
Bioactive small molecules produced by the human gut microbiome modulate Vibrio cholerae sessile and planktonic lifestyles. PMID:34006192
In vivo discovery of RNA proximal proteins via proximity-dependent biotinylation. PMID:34006179
Dual RNA-seq analysis of in vitro infection multiplicity and RNA depletion methods in Chlamydia-infected epithelial cells. PMID:34001998
PRMT6 activates cyclin D1 expression in conjunction with the transcription factor LEF1. PMID:34001852
Genome-wide detection of CNVs and their association with performance traits in broilers. PMID:34001004
Hybrid modelling for stroke care: Review and suggestions of new approaches for risk assessment and simulation of scenarios. PMID:34000646
Plasmids shape the diverse accessory resistomes of Escherichia coli ST131. PMID:33997610
Weighted Gene Co-expression Network Analysis Identifies CALD1 as a Biomarker Related to M2 Macrophages Infiltration in Stage III and IV Mismatch Repair-Proficient Colorectal Carcinoma. PMID:33996905
Identification of Molecular Subtypes and Key Genes of Atherosclerosis Through Gene Expression Profiles. PMID:33996893
Novel TNIP2 and TRAF2 Variants Are Implicated in the Pathogenesis of Pulmonary Arterial Hypertension. PMID:33996849
Evaluating the Consistency of Gene Methylation in Liver Cancer Using Bisulfite Sequencing Data. PMID:33996828
Identification of Key Functional Gene Signatures Indicative of Dedifferentiation in Papillary Thyroid Cancer. PMID:33996555
DNA methylation regulator-mediated modification patterns and tumor microenvironment characterization in gastric cancer. PMID:33996253
Association of NOS3-c.894G>T transversion with susceptibility to metabolic syndrome in Azar-cohort population: A case-control study and in silico analysis of the SNP molecular effects. PMID:33995953
Identification of the key target profiles underlying the drugs of narrow therapeutic index for treating cancer and cardiovascular disease. PMID:33995923
Construction of Unified Human Antimicrobial and Immunomodulatory Peptide Database and Examination of Antimicrobial and Immunomodulatory Peptides in Alzheimer's Disease Using Network Analysis of Proteomics Datasets. PMID:33995478
Proteomics and Machine Learning Approaches Reveal a Set of Prognostic Markers for COVID-19 Severity With Drug Repurposing Potential. PMID:33995121
Novel Insight Into the Role of Immune Dysregulation in Amyotrophic Lateral Sclerosis Based on Bioinformatic Analysis. PMID:33994932
Plasma Proteins As Biodosimetric Markers of Low-Dose Radiation in Mice. PMID:33994891
Bioinformatics and system biology approaches to identify the diseasome and comorbidities complexities of SARS-CoV-2 infection with the digestive tract disorders. PMID:33993223
Beta-adrenergic pathway activation enhances aggressiveness and inhibits stemness in head and neck cancer. PMID:33993095
Multimodality assessment of heart failure with preserved ejection fraction skeletal muscle reveals differences in the machinery of energy fuel metabolism. PMID:33991175
A native conjugative plasmid confers potential selective advantages to plant growth-promoting Bacillus velezensis strain GH1-13. PMID:33990691
CG6015 controls spermatogonia transit-amplifying divisions by epidermal growth factor receptor signaling in Drosophila testes. PMID:33990549
Hypoxia-Driven Oncometabolite L-2HG Maintains Stemness-Differentiation Balance and Facilitates Immune Evasion in Pancreatic Cancer. PMID:33990397
The role of TNFRSF11B in development of osteoarthritic cartilage. PMID:33989379
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease. PMID:33987940
Transcriptional analysis of muscle tissue and isolated satellite cells in spastic cerebral palsy. PMID:33987836
Mining TCGA database for gene expression in ovarian serous cystadenocarcinoma microenvironment. PMID:33987033
Screening and Identification of Key Microenvironment-Related Genes in Non-functioning Pituitary Adenoma. PMID:33986766
Development and Validation of an Interleukin-6 Nomogram to Predict Primary Non-response to Infliximab in Crohn's Disease Patients. PMID:33986682
Genomic selection signatures in autism spectrum disorder identifies cognitive genomic tradeoff and its relevance in paradoxical phenotypes of deficits versus potentialities. PMID:33986442
Melanocytes determine angiogenesis gene expression across human tissues. PMID:33983985
Molecular Regulation of the Melatonin Biosynthesis Pathway in Unipolar and Bipolar Depression. PMID:33981243
Gene4PD: A Comprehensive Genetic Database of Parkinson's Disease. PMID:33981200
A study of deregulated MMR pathways and anticancer potential of curcuma derivatives using computational approach. PMID:33980898
Landscape of allele-specific transcription factor binding in the human genome. PMID:33980847
Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences. PMID:33980308
Phylogenetic analysis of the salinipostin γ-butyrolactone gene cluster uncovers new potential for bacterial signalling-molecule diversity. PMID:33979276
CoffeeProt: an online tool for correlation and functional enrichment of systems genetics data. PMID:33978718
Development and validation of an oxidative stress-associated prognostic risk model for melanoma. PMID:33976978
Potential Mechanism of S. baicalensis on Lipid Metabolism Explored via Network Pharmacology and Untargeted Lipidomics. PMID:33976541
Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells. PMID:33976125
Polyadenylation-related isoform switching in human evolution revealed by full-length transcript structure. PMID:33973996
The Relationship Between Menopause and Metabolic Syndrome: Experimental and Bioinformatics Analysis. PMID:33973091
Intracranial VCAM1 at time of mechanical thrombectomy predicts ischemic stroke severity. PMID:33971895
An autoantigen profile of human A549 lung cells reveals viral and host etiologic molecular attributes of autoimmunity in COVID-19. PMID:33971585
Cross-Disorder Analysis of De Novo Mutations in Neuropsychiatric Disorders. PMID:33970367
Validation of the functions and prognostic values of synapse-associated proteins in lower-grade glioma. PMID:33969375
Genome-Wide Changes of Regulatory Non-Coding RNAs Reveal Pollen Development Initiated at Ecodormancy in Peach. PMID:33968979
Identification of VWF as a Novel Biomarker in Lung Adenocarcinoma by Comprehensive Analysis. PMID:33968738
Network Pharmacology-Based Prediction of Mechanism of Shenzhuo Formula for Application to DKD. PMID:33968154
Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3-Linked Sialic Acid Ligand Binding. PMID:33968084
Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints. PMID:33968050
A five metastasis-related long noncoding RNA risk signature for osteosarcoma survival prediction. PMID:33964903
Proteo3Dnet: a web server for the integration of structural information with interactomics data. PMID:33963857
Evidence for Selection in the Abundant Accessory Gene Content of a Prokaryote Pangenome. PMID:33963386
A New Sequential Forward Feature Selection (SFFS) Algorithm for Mining Best Topological and Biological Features to Predict Protein Complexes from Protein-Protein Interaction Networks (PPINs). PMID:33959851
Genes That Predict Poor Prognosis in Breast Cancer via Bioinformatical Analysis. PMID:33959662
Melatonin: Multi-Target Mechanism Against Diminished Ovarian Reserve Based on Network Pharmacology. PMID:33959095
The genome of a wild Medicago species provides insights into the tolerant mechanisms of legume forage to environmental stress. PMID:33957908
EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape. PMID:33956915
Functional and tissue enrichment analyses suggest that SARS-CoV-2 infection affects host metabolism and catabolism mediated by interference on host proteins. PMID:33956332
Association of urinary ketamine and APOA1 levels with bladder dysfunction in ketamine abusers revealed via proteomics and targeted metabolite analyses. PMID:33953300
Network pharmacology approach to decipher signaling pathways associated with target proteins of NSAIDs against COVID-19. PMID:33953223
A data-independent acquisition-based global phosphoproteomics system enables deep profiling. PMID:33953186
Predictive value of RAD51 on the survival and drug responsiveness of ovarian cancer. PMID:33952262
Identification of potential serum exosomal microRNAs involved in acinar-ductal metaplasia that is a precursor of pancreatic cancer associated with chronic pancreatitis. PMID:33950960
Mapping Angiotensin II Type 1 Receptor-Biased Signaling Using Proximity Labeling and Proteomics Identifies Diverse Actions of Biased Agonists. PMID:33950683
Quantitative Proteome Data Analysis of Tandem Mass Tags Labeled Samples. PMID:33950506
The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release. PMID:33950315
Young and early-onset dilated cardiomyopathy with malignant ventricular arrhythmia and sudden cardiac death induced by the heterozygous LDB3, MYH6, and SYNE1 missense mutations. PMID:33949037
Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures. PMID:33947863
Mediator of DNA Damage Checkpoint 1 (MDC1) Is a Novel Estrogen Receptor Coregulator in Invasive Lobular Carcinoma of the Breast. PMID:33947745
ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic Sarcomas. PMID:33946962
Bacterial Quality, Prevalence of Pathogens, and Molecular Characterization of Biofilm-Producing Staphylococcus aureus from Korean Dairy Farm Environments. PMID:33946614
Cartilage Protective and Immunomodulatory Features of Osteoarthritis Synovial Fluid-Treated Adipose-Derived Mesenchymal Stem Cells Secreted Factors and Extracellular Vesicles-Embedded miRNAs. PMID:33946524
Blood Transcriptomics of Turbot Scophthalmus maximus: A Tool for Health Monitoring and Disease Studies. PMID:33946507
lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms. PMID:33945509
MicroRNA-34a activation in tuberous sclerosis complex during early brain development may lead to impaired corticogenesis. PMID:33942341
Strategies for detecting and identifying biological signals amidst the variation commonly found in RNA sequencing data. PMID:33941086
Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer-based precipitation and size exclusion chromatography. PMID:33936570
The Pharmacological Activity of the Wenjing Decoction in Recurrent Spontaneous Abortion. PMID:33936247
Network Pharmacology and Molecular Docking Suggest the Mechanism for Biological Activity of Rosmarinic Acid. PMID:33936238
MCT4 Promotes Tumor Malignancy in F98 Glioma Cells. PMID:33936203
Arabidopsis thaliana EARLY RESPONSIVE TO DEHYDRATION 7 Localizes to Lipid Droplets via Its Senescence Domain. PMID:33936146
Designing Multi-Antigen Vaccines Against Acinetobacter baumannii Using Systemic Approaches. PMID:33936107
Variable Effects of PD-Risk Associated SNPs and Variants in Parkinsonism-Associated Genes on Disease Phenotype in a Community-Based Cohort. PMID:33935957
Comprehensive analysis of prognostic value and immune infiltration of kindlin family members in non-small cell lung cancer. PMID:33934696
Employing core regulatory circuits to define cell identity. PMID:33934382
Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease: an exploratory study. PMID:33933144
Systemic sclerosis biomarkers detection in the secretome of TGFβ1-activated primary human lung fibroblasts. PMID:33930553
Development and validation of epithelial mesenchymal transition-related prognostic model for hepatocellular carcinoma. PMID:33929972
Comparative Phosphoproteomics of Classical Bordetellae Elucidates the Potential Role of Serine, Threonine and Tyrosine Phosphorylation in Bordetella Biology and Virulence. PMID:33928046
The Underlying Molecular Mechanisms Involved in Traditional Chinese Medicine Smilax china L. for the Treatment of Pelvic Inflammatory Disease. PMID:33927774
Combined Transcriptomic and Proteomic Analysis of Perk Toxicity Pathways. PMID:33925631
Gene Expression Analysis of Microtubers of Potato Solanum tuberosum L. Induced in Cytokinin Containing Medium and Osmotic Stress. PMID:33925316
The Marine Natural Product Furospinulosin 1 Induces Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cell Spheroids, But Not in Cells Grown Traditionally with Longer Treatment. PMID:33924764
Comorbidities and Susceptibility to COVID-19: A Generalized Gene Set Data Mining Approach. PMID:33924631
Muscle Glycogen Phosphorylase and Its Functional Partners in Health and Disease. PMID:33924466
Proteomic and Bioinformatic Investigation of Altered Pathways in Neuroglobin-Deficient Breast Cancer Cells. PMID:33924212
Discovery-Versus Hypothesis-Driven Detection of Protein-Protein Interactions and Complexes. PMID:33923221
Proteomic Investigation of Glyceraldehyde-Derived Intracellular AGEs and Their Potential Influence on Pancreatic Ductal Cells. PMID:33923186
Muscle Proteomic and Transcriptomic Profiling of Healthy Aging and Metabolic Syndrome in Men. PMID:33921590
Study on the Sleep-Improvement Effects of Hemerocallis citrina Baroni in Drosophila melanogaster and Targeted Screening to Identify Its Active Components and Mechanism. PMID:33920660
Two Benthic Diatoms, Nanofrustulum shiloi and Striatella unipunctata, Encapsulated in Alginate Beads, Influence the Reproductive Efficiency of Paracentrotus lividus by Modulating the Gene Expression. PMID:33920652
Differential Epigenetic Marks Are Associated with Apospory Expressivity in Diploid Hybrids of Paspalum rufum. PMID:33920644
Deciphering the Methylation Landscape in Breast Cancer: Diagnostic and Prognostic Biosignatures through Automated Machine Learning. PMID:33918195
Pan-Cancer Analysis Reveals Distinct Metabolic Reprogramming in Different Epithelial-Mesenchymal Transition Activity States. PMID:33917859
Systematic Analysis of the Transcriptome Profiles and Co-Expression Networks of Tumour Endothelial Cells Identifies Several Tumour-Associated Modules and Potential Therapeutic Targets in Hepatocellular Carcinoma. PMID:33917186
Integrative RNA-Seq and H3 Trimethylation ChIP-Seq Analysis of Human Lung Cancer Cells Isolated by Laser-Microdissection. PMID:33916417
A computational method for drug sensitivity prediction of cancer cell lines based on various molecular information. PMID:33914775
Genome-wide association study of antipsychotic-induced sinus bradycardia in Chinese schizophrenia patients. PMID:33914752
Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis. PMID:33914608
Identification of Expression Patterns and Potential Prognostic Significance of m5C-Related Regulators in Head and Neck Squamous Cell Carcinoma. PMID:33912441
The Nek2 centrosome-mitotic kinase contributes to the mesenchymal state, cell invasion, and migration of triple-negative breast cancer cells. PMID:33907253
Transcriptional signatures in prefrontal cortex confer vulnerability versus resilience to food and cocaine addiction-like behavior. PMID:33907201
M6ADD: a comprehensive database of m6A modifications in diseases. PMID:33906563
Distinct diagnostic and prognostic values of Glypicans gene expression in patients with hepatocellular carcinoma. PMID:33902495
Interferon regulatory factor transcript levels correlate with clinical outcomes in human glioma. PMID:33902005
Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11. PMID:33901943
Triangulating Molecular Evidence to Prioritize Candidate Causal Genes at Established Atopic Dermatitis Loci. PMID:33901562
Comprehensive at-arrival transcriptomic analysis of post-weaned beef cattle uncovers type I interferon and antiviral mechanisms associated with bovine respiratory disease mortality. PMID:33901263
Small extracellular vesicle-encapsulated miR-181b-5p, miR-222-3p and let-7a-5p: Next generation plasma biopsy-based diagnostic biomarkers for inflammatory breast cancer. PMID:33901254
Systemic analysis of the expression levels and prognosis of breast cancer-related cadherins. PMID:33899544
EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer. PMID:33899001
Investigating Molecular Determinants of Cancer Cell Resistance to Ionizing Radiation Through an Integrative Bioinformatics Approach. PMID:33898418
Identification of Hub Genes and Construction of a Transcriptional Regulatory Network Associated With Tumor Recurrence in Colorectal Cancer by Weighted Gene Co-expression Network Analysis. PMID:33897765
Comparative Transcriptome Analysis of Key Genes and Pathways Activated in Response to Fat Deposition in Two Sheep Breeds With Distinct Tail Phenotype. PMID:33897762
Inhibition of IL-6 in the LCWE Mouse Model of Kawasaki Disease Inhibits Acute Phase Reactant Serum Amyloid A but Fails to Attenuate Vasculitis. PMID:33897686
A Novel Gene vp0610 Negatively Regulates Biofilm Formation in Vibrio parahaemolyticus. PMID:33897670
Shenling Baizhu Powder Inhibits RV-SA11-Induced Inflammation and Rotavirus Enteritis via TLR4/MyD88/NF-κB Signaling Pathway. PMID:33897431
Compound Dihuang Granule Inhibits Nigrostriatal Pathway Apoptosis in Parkinson's Disease by Suppressing the JNK/AP-1 Pathway. PMID:33897417
Study on the Prognostic Values of Dynactin Genes in Low-Grade Glioma. PMID:33896271
SIGNAL: A web-based iterative analysis platform integrating pathway and network approaches optimizes hit selection from genome-scale assays. PMID:33894945
Spatially resolved cell polarity proteomics of a human epiblast model. PMID:33893097
Effect of HPV 16 E6 Oncoprotein Variants on the Alterations of the Proteome of C33A Cells. PMID:33893080
Bioinformatics analysis of mRNA and miRNA microarray to identify the key miRNA-mRNA pairs in cisplatin-resistant ovarian cancer. PMID:33892654
High expression of COMMD7 is an adverse prognostic factor in acute myeloid leukemia. PMID:33891561
Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability. PMID:33889300
Are Mannan-binding Lectine Serin Protease-2 and Alpha-1-microglobulin and Bukinin Precursor the Potential Biomarkers of Manic Episode? A Study via Urinary Proetomic Analysis. PMID:33888656
Bioinformatics Analysis of the SIRT Family Members and Assessment of Their Potential Clinical Value. PMID:33883907
A Combination of RNA-Seq Analysis and Use of TCGA Database for Determining the Molecular Mechanism and Identifying Potential Drugs for GJB1 in Ovarian Cancer. PMID:33883906
Network Pharmacology Analysis of ZiShenWan for Diabetic Nephropathy and Experimental Verification of Its Anti-Inflammatory Mechanism. PMID:33883881
Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis. PMID:33879788
Varied clinical significance of ATP-binding cassette C sub-family members for lung adenocarcinoma. PMID:33879658
Urine proteomics for profiling of mouse toxoplasmosis using liquid chromatography tandem mass spectrometry analysis. PMID:33879238
SNRPD1 confers diagnostic and therapeutic values on breast cancers through cell cycle regulation. PMID:33879154
Comparative transcriptomics and network pharmacology analysis to identify the potential mechanism of celastrol against osteoarthritis. PMID:33870466
NASA GeneLab RNA-seq consensus pipeline: standardized processing of short-read RNA-seq data. PMID:33870146
A Non-canonical Wnt Signature Correlates With Lower Survival in Gastric Cancer. PMID:33869179
Construction of Competitive Endogenous RNA Network and Verification of 3-Key LncRNA Signature Associated With Distant Metastasis and Poor Prognosis in Patients With Clear Cell Renal Cell Carcinoma. PMID:33869028
Weighted Correlation Gene Network Analysis Reveals New Potential Mechanisms and Biomarkers in Non-obstructive Azoospermia. PMID:33868362
Identification and Functional Analysis of Long Non-coding RNAs in Human Pulmonary Microvascular Endothelial Cells Subjected to Cyclic Stretch. PMID:33868024
Ferroptosis-related Genes for Overall Survival Prediction in Patients with Colorectal Cancer can be Inhibited by Gallic acid. PMID:33867820
A form of muscular dystrophy associated with pathogenic variants in JAG2. PMID:33861953
Multiomics Analysis of Transcriptome, Epigenome, and Genome Uncovers Putative Mechanisms for Dilated Cardiomyopathy. PMID:33860048
Exploring the Role of Epicardial Adipose Tissue in Coronary Artery Disease From the Difference of Gene Expression. PMID:33859569
PCprophet: a framework for protein complex prediction and differential analysis using proteomic data. PMID:33859439
Interacting impact of maternal inflammatory response and stress on the amygdala transcriptome of pigs. PMID:33856433
Systematic analysis of the function and prognostic value of RNA binding proteins in Colon Adenocarcinoma. PMID:33854615
Bioinformatics analysis of lncRNA‑associated ceRNA network in melanoma. PMID:33854593
Identification of key regulators responsible for dysregulated networks in osteoarthritis by large-scale expression analysis. PMID:33853636
Functional analyses of human LUC7-like proteins involved in splicing regulation and myeloid neoplasms. PMID:33852859
Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer. PMID:33852841
An Autoantigen-ome from HS-Sultan B-Lymphoblasts Offers a Molecular Map for Investigating Autoimmune Sequelae of COVID-19. PMID:33851168
Identification of VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells. PMID:33851102
COL1A1 is a prognostic biomarker and correlated with immune infiltrates in lung cancer. PMID:33850663
Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model. PMID:33850167
Lifestyle-specific S-nitrosylation of protein cysteine thiols regulates Escherichia coli biofilm formation and resistance to oxidative stress. PMID:33850153
Bacterial Microcompartments Coupled with Extracellular Electron Transfer Drive the Anaerobic Utilization of Ethanolamine in Listeria monocytogenes. PMID:33850044
Expasy, the Swiss Bioinformatics Resource Portal, as designed by its users. PMID:33849055
Identification and analysis of key genes associated with acute myocardial infarction by integrated bioinformatics methods. PMID:33847684
Bioinformatics and system biology approach to identify the influences of SARS-CoV-2 infections to idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease patients. PMID:33847347
Intestinal microbiota drives cholestasis-induced specific hepatic gene expression patterns. PMID:33847205
CREB stimulates GPX4 transcription to inhibit ferroptosis in lung adenocarcinoma. PMID:33846793
Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. PMID:33846619
CRISPR screens identify a novel combination treatment targeting BCL-XL and WNT signaling for KRAS/BRAF-mutated colorectal cancers. PMID:33846570
Artificial intelligence to deep learning: machine intelligence approach for drug discovery. PMID:33844136
Nephron-deficient HSRA rats exhibit renal injury with age but have limited renal damage from streptozotocin-induced hyperglycemia. PMID:33843272
Nutrigenomics reveals potential genetic underpinning of diverse taste preference of Chinese men. PMID:33843022
Secondary analysis of transcriptomes of SARS-CoV-2 infection models to characterize COVID-19. PMID:33842903
Identification of hub genes and compounds controlling ovarian cancer stem cell characteristics via stemness indices analysis. PMID:33842600
mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2',4'-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications. PMID:33842373
Potential targets identified in adenoid cystic carcinoma point out new directions for further research. PMID:33841642
Nuclear factor IB is downregulated in vulvar squamous cell carcinoma (VSCC): Unravelling differentially expressed genes in VSCC through gene expression dataset analysis. PMID:33841565
Genetic alterations in Wnt family of genes and their putative association with head and neck squamous cell carcinoma. PMID:33840169
Functional annotation of lung cancer‒associated genetic variants by cell type‒specific epigenome and long-range chromatin interactome. PMID:33840167
Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway. PMID:33838689
Identification of transcriptomic signatures and crucial pathways involved in non-alcoholic steatohepatitis. PMID:33837926
Immune cells lacking Y chromosome show dysregulation of autosomal gene expression. PMID:33837451
Multiomics Analysis of Genetics and Epigenetics Reveals Pathogenesis and Therapeutic Targets for Atrial Fibrillation. PMID:33834070
Identification of a 5-Gene-Based Scoring System by WGCNA and LASSO to Predict Prognosis for Rectal Cancer Patients. PMID:33833937
Chlorogenic Acid Inhibits Human Glioma U373 Cell Progression via Regulating the SRC/MAPKs Signal Pathway: Based on Network Pharmacology Analysis. PMID:33833498
Prediction of Streptococcus uberis clinical mastitis treatment success in dairy herds by means of mass spectrometry and machine-learning. PMID:33833319
Predicting Protein-Protein Interactions Using Symmetric Logistic Matrix Factorization. PMID:33831302
Proteomic comparison between different tissue preservation methods for identification of promising biomarkers of urothelial bladder cancer. PMID:33828141
Plasma microrna expression profile for reduced ejection fraction in dilated cardiomyopathy. PMID:33824379
Screening of gene markers related to the prognosis of metastatic skin cutaneous melanoma based on Logit regression and survival analysis. PMID:33823876
Transcriptional control of parturition: insights from gene regulation studies in the myometrium. PMID:33823545
TWAS results are complementary to and less affected by linkage disequilibrium than GWAS. PMID:33823025
Ten Years of Collaborative Progress in the Quest for Orthologs. PMID:33822172
Gene expression evaluation of antioxidant enzymes in patients with hepatocellular carcinoma: RT-qPCR and bioinformatic analyses. PMID:33821873
Integrative bioinformatics analysis of KPNA2 in six major human cancers. PMID:33821218
Common genetic variants and pathways in diabetes and associated complications and vulnerability of populations with different ethnic origins. PMID:33820928
Machine learning-based investigation of the cancer protein secretory pathway. PMID:33819271
Human adipose-derived stem cells promote seawater-immersed wound healing via proangiogenic effects. PMID:33819183
Genome-Wide Association Identifies Risk Pathways for SAPHO Syndrome. PMID:33816493
Network Pharmacology Analysis of Traditional Chinese Medicine Formula Shuang Di Shou Zhen Tablets Treating Nonexudative Age-Related Macular Degeneration. PMID:33815556
Transcriptome Analysis Identifies Candidate Genes and Signaling Pathways Associated With Feed Efficiency in Xiayan Chicken. PMID:33815460
Hereditary Spastic Paraplegia: From Genes, Cells and Networks to Novel Pathways for Drug Discovery. PMID:33810178
Dilignans with a Chromanol Motif Discovered by Molecular Networking from the Stem Barks of Magnolia obovata and Their Proprotein Convertase Subtilisin/Kexin Type 9 Expression Inhibitory Activity. PMID:33808894
Bioinformatic Analysis of Structure and Function of LIM Domains of Human Zyxin Family Proteins. PMID:33808029
The Main Alkaloids in Uncaria rhynchophylla and Their Anti-Alzheimer's Disease Mechanism Determined by a Network Pharmacology Approach. PMID:33807157
Quantitative Proteomic Approach Reveals Altered Metabolic Pathways in Response to the Inhibition of Lysine Deacetylases in A549 Cells under Normoxia and Hypoxia. PMID:33806075
Gene Co-Expression Analysis of Human RNASEH2A Reveals Functional Networks Associated with DNA Replication, DNA Damage Response, and Cell Cycle Regulation. PMID:33805806
NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma. PMID:33805359
Behavioral and Gene Expression Analysis of Stxbp6-Knockout Mice. PMID:33805317
Musashi1 Contribution to Glioblastoma Development via Regulation of a Network of DNA Replication, Cell Cycle and Division Genes. PMID:33804958
Microglial Heterogeneity and Its Potential Role in Driving Phenotypic Diversity of Alzheimer's Disease. PMID:33803478
Combined De-Repression of Chemoresistance Associated Mitogen-Activated Protein Kinase 14 and Activating Transcription Factor 2 by Loss of microRNA-622 in Hepatocellular Carcinoma. PMID:33803354
A Streamlined Approach to Pathway Analysis from RNA-Sequencing Data. PMID:33802642
Diosmin Mitigates Cyclophosphamide Induced Premature Ovarian Insufficiency in Rat Model. PMID:33802633
Mining Complex Genetic Patterns Conferring Multiple Sclerosis Risk. PMID:33802599
Heterogeneous Off-Target Effects of Ultra-Low Dose Dimethyl Sulfoxide (DMSO) on Targetable Signaling Events in Lung Cancer In Vitro Models. PMID:33802212
Urinary Exosomes Identify Inflammatory Pathways in Vancomycin Associated Acute Kidney Injury. PMID:33801801
Epigenetic Mechanisms Are Involved in the Oncogenic Properties of ZNF518B in Colorectal Cancer. PMID:33801071
Protective Effects of Cannabidiol on the Membrane Proteome of UVB-Irradiated Keratinocytes. PMID:33800305
The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease Development. PMID:33799876
The Role of Autophagy and lncRNAs in the Maintenance of Cancer Stem Cells. PMID:33799834
Retinal Genomic Fabric Remodeling after Optic Nerve Injury. PMID:33799827
Mast Cell-Derived SAMD14 Is a Novel Regulator of the Human Prostate Tumor Microenvironment. PMID:33799802
Pancreatic Ductal Adenocarcinoma Arising in Young and Old Patients Displays Similar Molecular Features. PMID:33799792
Discovery of RSV-Induced BRD4 Protein Interactions Using Native Immunoprecipitation and Parallel Accumulation-Serial Fragmentation (PASEF) Mass Spectrometry. PMID:33799525
Interactome Mapping of eIF3A in a Colon Cancer and an Immortalized Embryonic Cell Line Using Proximity-Dependent Biotin Identification. PMID:33799492
The Impact of Modern Technologies on Molecular Diagnostic Success Rates, with a Focus on Inherited Retinal Dystrophy and Hearing Loss. PMID:33799353
Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development. PMID:33797837
Exploring the landscape of ectodomain shedding by quantitative protein terminomics. PMID:33796845
A deep learning framework for high-throughput mechanism-driven phenotype compound screening and its application to COVID-19 drug repurposing. PMID:33796820
Immune Interaction Map of Human SARS-CoV-2 Target Genes: Implications for Therapeutic Avenues. PMID:33796097
Exploring the differentially expressed genes in human lymphocytes upon response to ionizing radiation: a network biology approach. PMID:33794574
Gene Expression Changes in the Skin of Patients Undergoing Medial Thigh Liposuction With Pre-Surgical and Post-Surgical Application of Topical Products. PMID:33791656
Subgroup-Independent Mapping of Renal Cell Carcinoma-Machine Learning Reveals Prognostic Mitochondrial Gene Signature Beyond Histopathologic Boundaries. PMID:33791209
Exercise rapidly alters proteomes in mice following spinal cord demyelination. PMID:33790323
An in silico model using prognostic genetic factors for ovarian response in controlled ovarian stimulation: A systematic review. PMID:33788133
Analysis of mRNA expression differences in bladder cancer metastasis based on TCGA datasets. PMID:33787386
Following up of Surgical Treated Human Liver Cystic Echinococcosis: A Proteomics Approach. PMID:33786043
Integration of multi-omics approaches for functional characterization of muscle related selective sweep genes in Nanchukmacdon. PMID:33785872
Systems Biology behind Immunoprotection of Both Sheep and Goats after Sungri/96 PPRV Vaccination. PMID:33785572
Aconiti lateralis Radix Praeparata inhibits Alzheimer's disease by regulating the complex regulation network with the core of GRIN1 and MAPK1. PMID:33784489
Genome-wide RNAi screen for regulators of UPRmt in Caenorhabditis elegans mutants with defects in mitochondrial fusion. PMID:33784383
Quantitative acetylome analysis reveals histone modifications that may predict prognosis in hepatitis B-related hepatocellular carcinoma. PMID:33783990
Screening of osteoarthritis diagnostic markers based on immune-related genes and immune infiltration. PMID:33782454
Proteomic analysis identifies the RNA helicase DDX3X as a host target against SARS-CoV-2 infection. PMID:33781803
Viral genomic, metagenomic and human transcriptomic characterization and prediction of the clinical forms of COVID-19. PMID:33780519
In silico analysis of phylogeny, structure, and function of arsenite oxidase from unculturable microbiome of arsenic contaminated soil. PMID:33779860
A Network Pharmacology to Explore the Mechanism of Calculus Bovis in the Treatment of Ischemic Stroke. PMID:33778069
Identification of Proteins Deregulated by Platinum-Based Chemotherapy as Novel Biomarkers and Therapeutic Targets in Non-Small Cell Lung Cancer. PMID:33777753
Functional Network of the Long Non-coding RNA Growth Arrest-Specific Transcript 5 and Its Interacting Proteins in Senescence. PMID:33777096
Carvacrol, Thymol, and Garlic Essential Oil Promote Skin Innate Immunity in Gilthead Seabream (Sparus aurata) Through the Multifactorial Modulation of the Secretory Pathway and Enhancement of Mucus Protective Capacity. PMID:33777020
The Redox Proteome of Thiol Proteins in the Rice Blast Fungus Magnaporthe oryzae. PMID:33776980
The Potential of hsa-mir-106b-5p as Liquid Biomarker in Prostate Cancer Patients in Indonesia. PMID:33773548
Analysis of human total antibody repertoires in TIF1γ autoantibody positive dermatomyositis. PMID:33772100
Discovery of New Protein Targets of BPA Analogs and Derivatives Associated with Noncommunicable Diseases: A Virtual High-Throughput Screening. PMID:33769846
Loss-of-Function Variants in the SYNPO2L Gene Are Associated With Atrial Fibrillation. PMID:33768119
Prognostic Signature of Immune Genes and Immune-Related LncRNAs in Neuroblastoma: A Study Based on GEO and TARGET Datasets. PMID:33767996
CXC Chemokines as Therapeutic Targets and Prognostic Biomarkers in Skin Cutaneous Melanoma Microenvironment. PMID:33767987
Structural and Drug Screening Analysis of the Non-structural Proteins of Severe Acute Respiratory Syndrome Coronavirus 2 Virus Extracted From Indian Coronavirus Disease 2019 Patients. PMID:33767730
Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor. PMID:33766124
Glibenclamide, ATP and metformin increases the expression of human bile salt export pump ABCB11. PMID:33763207
High Glucose Causes Distinct Expression Patterns of Primary Human Skin Cells by RNA Sequencing. PMID:33763026
Protein cleavage influences surface protein presentation in Mycoplasma pneumoniae. PMID:33762641
TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6. PMID:33762006
A 2 miRNAs-based signature for the diagnosis of atherosclerosis. PMID:33761890
Prognostic significance and immune infiltration of microenvironment-related signatures in pancreatic cancer. PMID:33761652
Functional genomics study of protein inhibitor of activated STAT1 in mouse hippocampal neuronal cells revealed by RNA sequencing. PMID:33759814
Identification of tumor mutation burden-related hub genes and the underlying mechanism in melanoma. PMID:33758620
Identification of Prognosis-related Hub RNA Binding Proteins Function through Regulating Metabolic Processes in Tongue Cancer. PMID:33758601
Transcriptomic analysis of the trade-off between endurance and burst-performance in the frog Xenopus allofraseri. PMID:33757428
Corneal proteome and differentially expressed corneal proteins in highly myopic chicks using a label-free SWATH-MS quantification approach. PMID:33750851
Comprehensive analysis of ceRNA networks reveals prognostic lncRNAs related to immune infiltration in colorectal cancer. PMID:33750326
Identification of 11 candidate structured noncoding RNA motifs in humans by comparative genomics. PMID:33750298
Integrated intra- and intercellular signaling knowledge for multicellular omics analysis. PMID:33749993
A small molecule compound berberine as an orally active therapeutic candidate against COVID-19 and SARS: A computational and mechanistic study. PMID:33749932
Noise regularization removes correlation artifacts in single-cell RNA-seq data preprocessing. PMID:33748795
A Novel Nine Apoptosis-Related Genes Signature Predicting Overall Survival for Kidney Renal Clear Cell Carcinoma and its Associations with Immune Infiltration. PMID:33748185
Kinome-Wide RNAi Screen Uncovers Role of Ballchen in Maintenance of Gene Activation by Trithorax Group in Drosophila. PMID:33748127
Identification of Potential Diagnostic Gene Targets for Pediatric Sepsis Based on Bioinformatics and Machine Learning. PMID:33748037
Comprehensive Analysis of the Immune and Prognostic Implication of COL6A6 in Lung Adenocarcinoma. PMID:33747955
Identification of potential oncogenes in triple-negative breast cancer based on bioinformatics analyses. PMID:33747220
Bioinformatics identification of the candidate microRNAs and construction of a competing endogenous RNA regulatory network in lacrimal gland adenoid cystic carcinoma high-grade transformation. PMID:33747217
Transcriptome analysis of sinensetin-treated liver cancer cells guided by biological network analysis. PMID:33747212
Targeting of FK506 binding protein 5 by miR-203 affects the progression of breast cancer via regulating the fatty acid degradation pathway and potential drug-repurposing. PMID:33747203
Network Pharmacology and Pharmacological Evaluation Reveals the Mechanism of the Sanguisorba Officinalis in Suppressing Hepatocellular Carcinoma. PMID:33746755
Elucidation of the Mechanism of Action of Ginseng Against Acute Lung Injury/Acute Respiratory Distress Syndrome by a Network Pharmacology-Based Strategy. PMID:33746744
A network pharmacology based approach for predicting active ingredients and potential mechanism of Lianhuaqingwen capsule in treating COVID-19. PMID:33746604
Expression and molecular profiles of the AlkB family in ovarian serous carcinoma. PMID:33744868
Pan-cancer analysis identifies ITIH1 as a novel prognostic indicator for hepatocellular carcinoma. PMID:33744857
Prognostic impact of the glypican family of heparan sulfate proteoglycans on the survival of breast cancer patients. PMID:33742285
Adipocytes Under Obese-Like Conditions Change Cell Cycle Distribution and Phosphorylation Profiles of Breast Cancer Cells: The Adipokine Receptor CAP1 Matters. PMID:33738261
Nidogen-1 expression is associated with overall survival and temozolomide sensitivity in low-grade glioma patients. PMID:33735110
Aberrant proteins expressed in skin fibroblasts of Parkinson's disease patients carrying heterozygous variants of glucocerebrosidase and parkin genes. PMID:33732455
Rapid Induction of Pulmonary Inflammation, Autoimmune Gene Expression, and Ectopic Lymphoid Neogenesis Following Acute Silica Exposure in Lupus-Prone Mice. PMID:33732257
Integrated Proteomics and Bioinformatics to Identify Potential Prognostic Biomarkers in Hepatocellular Carcinoma. PMID:33732023
Pediatric MDS and bone marrow failure-associated germline mutations in SAMD9 and SAMD9L impair multiple pathways in primary hematopoietic cells. PMID:33731850
Regulation of olfactomedin 4 by Porphyromonas gingivalis in a community context. PMID:33731837
Temporal mechanisms of myogenic specification in human induced pluripotent stem cells. PMID:33731358
Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung. PMID:33731112
Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease. PMID:33730931
In-silico structural analysis of Pseudomonas syringae effector HopZ3 reveals ligand binding activity and virulence function. PMID:33730245
Synergistic Network Pharmacology for Traditional Chinese Medicine Liangxue Tongyu Formula in Acute Intracerebral Hemorrhagic Stroke. PMID:33727915
Downregulation of Zn-transporters along with Fe and redox imbalance causes growth and photosynthetic disturbance in Zn-deficient tomato. PMID:33727682
A ligand-receptor interactome platform for discovery of pain mechanisms and therapeutic targets. PMID:33727337
A study of the heterochronic sense/antisense RNA representation in florets of sexual and apomictic Paspalum notatum. PMID:33726667
Cardiac retinoic acid levels decline in heart failure. PMID:33724958
Microglial trogocytosis and the complement system regulate axonal pruning in vivo. PMID:33724186
Computational approach to decipher cellular interactors and drug targets during co-infection of SARS-CoV-2, Dengue, and Chikungunya virus. PMID:33723515
Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent. PMID:33723368
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart. PMID:33723250
Machine learning analysis of gene expression profile reveals a novel diagnostic signature for osteoporosis. PMID:33722258
The characteristics of circRNA as competing endogenous RNA in pathogenesis of acute myeloid leukemia. PMID:33722210
Genetic association and causal inference converge on hyperglycaemia as a modifiable factor to improve lung function. PMID:33720009
Tracing and exploring the evolutionary origin and systematic function of fish complement C9. PMID:33718983
Identification of Core Genes and Screening of Potential Targets in Glioblastoma Multiforme by Integrated Bioinformatic Analysis. PMID:33718116
The expression patterns and prognostic significance of pleckstrin homology-like domain family A (PHLDA) in lung cancer and malignant mesothelioma. PMID:33717542
Identification and validation of a prognostic signature and combination drug therapy for immunotherapy of head and neck squamous cell carcinoma. PMID:33717423
Do Molecular Profiles of Primary Versus Metastatic Radioiodine Refractory Differentiated Thyroid Cancer Differ? PMID:33716974
Protein Biomarkers of Autism Spectrum Disorder Identified by Computational and Experimental Methods. PMID:33716802
The role of WDR76 protein in human diseases. PMID:33714259
The Arabidopsis mediator complex subunit 8 regulates oxidative stress responses. PMID:33713138
Functional repertoire of EV-associated miRNA profiles after lipoprotein depletion via ultracentrifugation and size exclusion chromatography from autologous blood products. PMID:33712660
A prognostic model for hepatocellular carcinoma based on apoptosis-related genes. PMID:33712023
Identification of four key prognostic genes and three potential drugs in human papillomavirus negative head and neck squamous cell carcinoma. PMID:33712015
Repurposing novel therapeutic candidate drugs for coronavirus disease-19 based on protein-protein interaction network analysis. PMID:33711981
Integrated analysis of RNA-binding proteins in thyroid cancer. PMID:33711033
Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling. PMID:33710653
Transcriptomic Data Analyses Reveal That Sow Fertility-Related lincRNA NORFA Is Essential for the Normal States and Functions of Granulosa Cells. PMID:33708768
Omics-Driven Biotechnology for Industrial Applications. PMID:33708762
Identification of TRIM56 as a Potential Biomarker for Lung Adenocarcinoma. PMID:33707970
Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma. PMID:33707956
Comprehensive analysis of autophagy-related genes and patterns of immune cell infiltration in valvular atrial fibrillation. PMID:33706714
A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models. PMID:33705438
Longitudinal proteomic profiling of dialysis patients with COVID-19 reveals markers of severity and predictors of death. PMID:33704068
TETology: Epigenetic Mastermind in Action. PMID:33694104
Machine Learning Identifies Complicated Sepsis Course and Subsequent Mortality Based on 20 Genes in Peripheral Blood Immune Cells at 24 H Post-ICU Admission. PMID:33692779
Whole Genome Sequencing Prioritizes CHEK2, EWSR1, and TIAM1 as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer. PMID:33692755
Integrative network analyses of transcriptomics data reveal potential drug targets for acute radiation syndrome. PMID:33692493
Molecular characterization of Fe-acquisition genes causing decreased Fe uptake and photosynthetic inefficiency in Fe-deficient sunflower. PMID:33692433
Changes in protein expression due to metformin treatment and hyperinsulinemia in a human endometrial cancer cell line. PMID:33690729
Increased numbers of nucleoli in a genome-wide RNAi screen reveal proteins that link the cell cycle to RNA polymerase I transcription. PMID:33689394
Comparison of the Fatty Acid Metabolism Pathway in Pan-Renal Cell Carcinoma: Evidence from Bioinformatics. PMID:33688464
Identification of suitable reference genes for mesenchymal stem cells from menstrual blood of women with endometriosis. PMID:33686153
The construction and validation of an RNA binding protein-related prognostic model for bladder cancer. PMID:33685397
A network-informed analysis of SARS-CoV-2 and hemophagocytic lymphohistiocytosis genes' interactions points to Neutrophil extracellular traps as mediators of thrombosis in COVID-19. PMID:33684134
An Update on MRMAssayDB: A Comprehensive Resource for Targeted Proteomics Assays in the Community. PMID:33683131
Human Bone Proteomes before and after Decomposition: Investigating the Effects of Biological Variation and Taphonomic Alteration on Bone Protein Profiles and the Implications for Forensic Proteomics. PMID:33683123
DeepViral: prediction of novel virus-host interactions from protein sequences and infectious disease phenotypes. PMID:33682875
A novel seven-gene panel predicts the sensitivity and prognosis of head and neck squamous cell carcinoma treated with platinum-based radio(chemo)therapy. PMID:33682046
Decoding the Mechanism of Huanglian Jiedu Decoction in Treating Pneumonia Based on Network Pharmacology and Molecular Docking. PMID:33681222
Medication for Acromegaly Reduces Expression of MUC16, MACC1 and GRHL2 in Pituitary Neuroendocrine Tumour Tissue. PMID:33680922
Multiple Myeloma Cells Alter Adipogenesis, Increase Senescence-Related and Inflammatory Gene Transcript Expression, and Alter Metabolism in Preadipocytes. PMID:33680918
Down-Regulation of MiR-181c-5p Promotes Epithelial-to-Mesenchymal Transition in Laryngeal Squamous Cell Carcinoma via Targeting SERPINE1. PMID:33680908
Integrated Network and Gene Ontology Analysis Identifies Key Genes and Pathways for Coronary Artery Diseases. PMID:33680369
Case Report: Whole Exome Sequencing Revealed Disease-Causing Variants in Two Genes in a Patient With Autism Spectrum Disorder, Intellectual Disability, Hyperactivity, Sleep and Gastrointestinal Disturbances. PMID:33679889
Construction and Comprehensive Analyses of a METTL5-Associated Prognostic Signature With Immune Implication in Lung Adenocarcinomas. PMID:33679869
Network Topological Analysis for the Identification of Novel Hubs in Plant Nutrition. PMID:33679842
A Molecular Interaction Map of Klebsiella pneumoniae and Its Human Host Reveals Potential Mechanisms of Host Cell Subversion. PMID:33679637
Identification of FPR3 as a Unique Biomarker for Targeted Therapy in the Immune Microenvironment of Breast Cancer. PMID:33679387
The Effects of Selective Inhibition of Histone Deacetylase 1 and 3 in Huntington's Disease Mice. PMID:33679321
Dynamic blood single-cell immune responses in patients with COVID-19. PMID:33677468
Key metabolism pathways and regulatory mechanisms of high polysaccharide yielding in Hericium erinaceus. PMID:33676419
Transcriptome Analysis of the Anti-TGFβ Effect of Schisandra chinensis Fruit Extract and Schisandrin B in A7r5 Vascular Smooth Muscle Cells. PMID:33672474
Genetic Adaptations in Mudskipper and Tetrapod Give Insights into Their Convergent Water-to-Land Transition. PMID:33672418
Nitric Oxide (NO) Scaffolds the Peroxisomal Protein-Protein Interaction Network in Higher Plants. PMID:33671021
Genome-Wide Characterization, Evolution, and Expression Profile Analysis of GATA Transcription Factors in Brachypodium distachyon. PMID:33670757
Network Analysis Identifies Drug Targets and Small Molecules to Modulate Apoptosis Resistant Cancers. PMID:33670487
Ionizing Radiation Protein Biomarkers in Normal Tissue and Their Correlation to Radiosensitivity: A Systematic Review. PMID:33669522
LAT1 and ASCT2 Related microRNAs as Potential New Therapeutic Agents against Colorectal Cancer Progression. PMID:33669301
Knowledge-Guided "Community Network" Analysis Reveals the Functional Modules and Candidate Targets in Non-Small-Cell Lung Cancer. PMID:33669233
Multi-Omics Data Analysis of Gene Expressions and Alterations, Cancer-Associated Fibroblast and Immune Infiltrations, Reveals the Onco-Immune Prognostic Relevance of STAT3/CDK2/4/6 in Human Malignancies. PMID:33668805
FOXC1 Downregulates Nanog Expression by Recruiting HDAC2 to Its Promoter in F9 Cells Treated by Retinoic Acid. PMID:33668324
Sequential perturbations to mouse corticogenesis following in utero maternal immune activation. PMID:33666173
Comprehensive Analysis of CDCAs Methylation and Immune Infiltrates in Hepatocellular Carcinoma. PMID:33665158
Effects of estrogen inhibition formula herbal mixture for danazol-induced precocious puberty in female rats: an experimental study with network pharmacology. PMID:33665096
Multiple Regionalized Genes and Their Putative Networks in the Interpeduncular Nucleus Suggest Complex Mechanisms of Neuron Development and Axon Guidance. PMID:33664652
A comparative analysis of heart microRNAs in vertebrates brings novel insights into the evolution of genetic regulatory networks. PMID:33663371
Treatment of Spleen-Deficiency Syndrome With Atractyloside A From Bran-Processed Atractylodes lancea by Protection of the Intestinal Mucosal Barrier. PMID:33658928
Reduced expression of innate immunity-related genes in lymph node metastases of luminal breast cancer patients. PMID:33658651
Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis. PMID:33658400
The aging-related risk signature in colorectal cancer. PMID:33658390
A Network Pharmacology Study of the Molecular Mechanisms of Hypericum japonicum in the Treatment of Cholestatic Hepatitis with Validation in an Alpha-Naphthylisothiocyanate (ANIT) Hepatotoxicity Rat Model. PMID:33657087
An Autoantigen Profile of Human A549 Lung Cells Reveals Viral and Host Etiologic Molecular Attributes of Autoimmunity in COVID-19. PMID:33655248
Prognostic biomarker TUBA1C is correlated to immune cell infiltration in the tumor microenvironment of lung adenocarcinoma. PMID:33653340
Multi-species transcriptome meta-analysis of the response to retinoic acid in vertebrates and comparative analysis of the effects of retinol and retinoic acid on gene expression in LMH cells. PMID:33653267
hnRNP L is essential for myogenic differentiation and modulates myotonic dystrophy pathologies. PMID:33651408
Identification of a PLCE1‑regulated competing endogenous RNA regulatory network for esophageal squamous cell carcinoma. PMID:33650665
Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics. PMID:33649493
Disproportionate left atrial myopathy in heart failure with preserved ejection fraction among participants of the PROMIS-HFpEF study. PMID:33649383
Adaptive evolution of hybrid bacteria by horizontal gene transfer. PMID:33649202
Construction of the optimization prognostic model based on differentially expressed immune genes of lung adenocarcinoma. PMID:33648465
A Prognostic Model Based on RNA Binding Protein Predicts Clinical Outcomes in Hepatocellular Carcinoma Patients. PMID:33643914
Proteome-minimized outer membrane vesicles from Escherichia coli as a generalized vaccine platform. PMID:33643549
Identification of Prognostic Stromal-Immune Score-Based Genes in Hepatocellular Carcinoma Microenvironment. PMID:33643387
Transcriptome Characterization of Short Distance Transport Stress in Beef Cattle Blood. PMID:33643382
Mitochondrial Small Heat Shock Proteins Are Essential for Normal Growth of Arabidopsis thaliana. PMID:33643342
Immune profiles of male giant panda (Ailuropoda melanoleuca) during the breeding season. PMID:33639852
Complete Genome Sequence of Pedobacter sp. PAMC26386 and Their Low Temperature Application in Arabinose-containing Polysaccharides Degradation. PMID:33638002
A molecular quantitative trait locus map for osteoarthritis. PMID:33637762
Sirtuin 2 Prevents Liver Steatosis and Metabolic Disorders by Deacetylation of Hepatocyte Nuclear Factor 4α. PMID:33636024
Integrated study of miR-215 promoting breast cancer cell apoptosis by targeting RAD54B. PMID:33635591
Forkhead transcription factor Fkh1: insights into functional regulatory domains crucial for recruitment of Sin3 histone deacetylase complex. PMID:33635403
Exploring the mechanisms underlying the therapeutic effect of Salvia miltiorrhiza in diabetic nephropathy using network pharmacology and molecular docking. PMID:33634308
Exploring the conservation of Alzheimer-related pathways between H. sapiens and C. elegans: a network alignment approach. PMID:33633188
DNA methylation and cancer incidence: lymphatic-hematopoietic versus solid cancers in the Strong Heart Study. PMID:33632303
Bioinformatics analysis of the prognosis and biological significance of VCAN in gastric cancer. PMID:33631054
Identification BCL6 and miR-30 family associating with Ibrutinib resistance in activated B-cell-like diffuse large B-cell lymphoma. PMID:33629212
Based on Network Pharmacology Tools to Investigate the Molecular Mechanism of Cordyceps sinensis on the Treatment of Diabetic Nephropathy. PMID:33628839
miR-193a-3p Promotes the Invasion, Migration, and Mesenchymal Transition in Glioma through Regulating BTRC. PMID:33628829
Analysis of Differentially Expressed Genes in the Dentate Gyrus and Anterior Cingulate Cortex in a Mouse Model of Depression. PMID:33628784
Construction and Analysis of Survival-Associated Competing Endogenous RNA Network in Lung Adenocarcinoma. PMID:33628780
Mechanism of Modified Danggui Sini Decoction for Knee Osteoarthritis Based on Network Pharmacology and Molecular Docking. PMID:33628311
Uncovering the Anti-Lung-Cancer Mechanisms of the Herbal Drug FDY2004 by Network Pharmacology. PMID:33628308
A Network Pharmacology Study on the Molecular Mechanisms of FDY003 for Breast Cancer Treatment. PMID:33628298
Exploration of Prognostic Biomarkers among Replication Factor C Family in the Hepatocellular Carcinoma. PMID:33628006
RNA Sequencing of Decidua Reveals Differentially Expressed Genes in Recurrent Pregnancy Loss. PMID:33625691
Exonuclease 1 (EXO1) is a Potential Prognostic Biomarker and Correlates with Immune Infiltrates in Lung Adenocarcinoma. PMID:33623391
Automating parameter selection to avoid implausible biological pathway models. PMID:33623016
Extracellular vesicles from HTLV-1 infected cells modulate target cells and viral spread. PMID:33622348
Identification of hub genes correlated with sleep deprivation using co-expression analysis. PMID:33619665
Concomitant gain and loss of function pathomechanisms in C9ORF72 amyotrophic lateral sclerosis. PMID:33619157
Inferring perturbation profiles of cancer samples. PMID:33617647
A Risk Prediction Model for Breast Cancer Based on Immune Genes Related to Early Growth Response Proteins Family. PMID:33614706
Proteomic profile of melanoma cell-derived small extracellular vesicles in patients' plasma: a potential correlate of melanoma progression. PMID:33613873
Light Regulates the Cytokinin-Dependent Cold Stress Responses in Arabidopsis. PMID:33613584
Skin Multi-Omics-Based Interactome Analysis: Integrating the Tissue and Mucus Exuded Layer for a Comprehensive Understanding of the Teleost Mucosa Functionality as Model of Study. PMID:33613538
Development and validation of an individual alternative splicing prognostic signature in gastric cancer. PMID:33612482
Hsa_circ_0038383-mediated competitive endogenous RNA network in recurrent implantation failure. PMID:33611311
Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension. PMID:33608545
RNA-Seq in Nonmodel Organisms. PMID:33606257
Identification of pathways modulating vemurafenib resistance in melanoma cells via a genome-wide CRISPR/Cas9 screen. PMID:33604667
Targeted Gene Candidates for Treatment and Early Diagnosis of Age-Related Macular Degeneration. PMID:33604378
Genome-Wide Characterization and Expression Analysis of the HD-ZIP Gene Family in Response to Salt Stress in Pepper. PMID:33604369
Comprehensive Analysis of Prognostic and Immune Infiltrates for E2F Transcription Factors in Human Pancreatic Adenocarcinoma. PMID:33604289
In silico identification of potential inhibitor for TP53-induced glycolysis and apoptosis regulator in head and neck squamous cell carcinoma. PMID:33604233
Phloem Sap Proteins Are Part of a Core Stress Responsive Proteome Involved in Drought Stress Adjustment. PMID:33603764
Network Pharmacology-Based Approach to Investigate the Molecular Targets of Sinomenine for Treating Breast Cancer. PMID:33603465
Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. PMID:33603002
Plasma microRNA signature associated with retinopathy in patients with type 2 diabetes. PMID:33602976
The acyltransferase PMAT1 malonylates brassinolide glucoside. PMID:33600798
Comprehensive Succinylome Profiling Reveals the Pivotal Role of Lysine Succinylation in Energy Metabolism and Quorum Sensing of Staphylococcus epidermidis. PMID:33597936
Inference and analysis of cell-cell communication using CellChat. PMID:33597522
The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction. PMID:33596422
Rare deleterious germline variants and risk of lung cancer. PMID:33594163
Interaction between G ALNT12 and C1GALT1 Associates with Galactose-Deficient IgA1 and IgA Nephropathy. PMID:33593824
Converting disease maps into heavyweight ontologies: general methodology and application to Alzheimer's disease. PMID:33590873
Creation of a gene expression portrait of depression and its application for identifying potential treatments. PMID:33589676
SARS-CoV-2 Proteins Exploit Host's Genetic and Epigenetic Mediators for the Annexation of Key Host Signaling Pathways. PMID:33585554
A Novel Early-Stage Lung Adenocarcinoma Prognostic Model Based on Feature Selection With Orthogonal Regression. PMID:33585460
PRSS1 Upregulation Predicts Platinum Resistance in Ovarian Cancer Patients. PMID:33585454
Identification of the Myogenetic Oligodeoxynucleotides (myoDNs) That Promote Differentiation of Skeletal Muscle Myoblasts by Targeting Nucleolin. PMID:33585451
Screening of JAK-STAT modulators from the antiviral plants of Indian traditional system of medicine with the potential to inhibit 2019 novel coronavirus using network pharmacology. PMID:33585152
Construction of an RNA-Binding Protein-Related Prognostic Model for Pancreatic Adenocarcinoma Based on TCGA and GTEx Databases. PMID:33584809
Protein Phosphorylation in Depolarized Synaptosomes: Dissecting Primary Effects of Calcium from Synaptic Vesicle Cycling. PMID:33582301
Association of P2X7 receptor genetic polymorphisms and expression with rheumatoid arthritis susceptibility in a sample of the Iranian population: a case-control study. PMID:33580375
Modifiers of CAG/CTG Repeat Instability: Insights from Mammalian Models. PMID:33579861
Integrated analysis of differentially expressed genes and construction of a competing endogenous RNA network in human Huntington neural progenitor cells. PMID:33579286
Clinical prognosis and bioinformatic analysis of primary thyroid lymphoma. PMID:33578562
Identification of key biomarkers and functional pathways in osteosarcomas with lung metastasis: Evidence from bioinformatics analysis. PMID:33578541
Leveraging the antiviral type I interferon system as a first line of defense against SARS-CoV-2 pathogenicity. PMID:33577760
TranSynergy: Mechanism-driven interpretable deep neural network for the synergistic prediction and pathway deconvolution of drug combinations. PMID:33577560
Development and Validation of a 5-Gene Autophagy-Based Prognostic Index in Endometrial Carcinoma. PMID:33577492
Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease. PMID:33576571
Untangling biological factors influencing trajectory inference from single cell data. PMID:33575604
CLIP4 Shows Putative Tumor Suppressor Characteristics in Breast Cancer: An Integrated Analysis. PMID:33575272
A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation. PMID:33575256
Gene expression profiling of CD34(+) cells from patients with myeloproliferative neoplasms. PMID:33574943
CC Chemokine Receptors in Lung Adenocarcinoma: The Inflammation-Related Prognostic Biomarkers and Immunotherapeutic Targets. PMID:33574689
Phosphoproteomic Analysis as an Approach for Understanding Molecular Mechanisms of cAMP-Dependent Actions. PMID:33574048
Time-Course Changes of Extracellular Matrix Encoding Genes Expression Level in the Spinal Cord Following Contusion Injury-A Data-Driven Approach. PMID:33572341
Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells. PMID:33572239
A Proteomics Analysis of Calmodulin-Binding Proteins in Dictyostelium discoideum during the Transition from Unicellular Growth to Multicellular Development. PMID:33572113
miR-16-5p Promotes Erythroid Maturation of Erythroleukemia Cells by Regulating Ribosome Biogenesis. PMID:33572085
The Coding and Small Non-coding Hippocampal Synaptic RNAome. PMID:33569760
Integrated network analysis reveals new genes suggesting COVID-19 chronic effects and treatment. PMID:33569598
Elevated Heterogeneous Nuclear Ribonucleoprotein C Expression Correlates With Poor Prognosis in Patients With Surgically Resected Lung Adenocarcinoma. PMID:33569346
LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C. PMID:33568674
Akt kinase LANCL2 functions as a key driver in EGFR-mutant lung adenocarcinoma tumorigenesis. PMID:33568630
Subcellular Localization of uc.8+ as a Prognostic Biomarker in Bladder Cancer Tissue. PMID:33567603
Perinatal granulopoiesis and risk of pediatric asthma. PMID:33565964
Transcriptomic Analyses Reveal Gene Expression Profiles and Networks in Nasopharyngeal Carcinoma. PMID:33564686
Key regulatory genes and signaling pathways involved in islet culture: a bioinformatic analysis. PMID:33564361
A genome-wide association study for gut metagenome in Chinese adults illuminates complex diseases. PMID:33563976
Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945. PMID:33562780
The Ins and Outs of RAS Effector Complexes. PMID:33562401
Current and prospective computational approaches and challenges for developing COVID-19 vaccines. PMID:33561453
A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience. PMID:33561251
ADAP is a possible negative regulator of glucosinolate biosynthesis in Arabidopsis thaliana based on clustering and gene expression analyses. PMID:33558947
Integrated analysis identifies oxidative stress genes associated with progression and prognosis in gastric cancer. PMID:33558567
Role of Pirin, an Oxidative Stress Sensor Protein, in Epithelial Carcinogenesis. PMID:33557375
Ileum Gene Expression in Response to Acute Systemic Inflammation in Mice Chronically Fed Ethanol: Beneficial Effects of Elevated Tissue n-3 PUFAs. PMID:33557303
TREM2 Mediates Microglial Anti-Inflammatory Activations in Alzheimer's Disease: Lessons Learned from Transcriptomics. PMID:33557250
Integrative Genomic-Epigenomic Analysis of Clozapine-Treated Patients with Refractory Psychosis. PMID:33557049
A four-genes based diagnostic signature for osteoarthritis. PMID:33555399
Yeast translation elongation factor eEF3 promotes late stages of tRNA translocation. PMID:33555093
FOXP1 Interacts with MyoD to Repress its Transcription and Myoblast Conversion. PMID:33554216
Integrative Identification of Hub Genes Associated With Immune Cells in Atrial Fibrillation Using Weighted Gene Correlation Network Analysis. PMID:33553270
Mdfi Promotes C2C12 Cell Differentiation and Positively Modulates Fast-to-Slow-Twitch Muscle Fiber Transformation. PMID:33553177
Multi-Omics Analysis of Acute Lymphoblastic Leukemia Identified the Methylation and Expression Differences Between BCP-ALL and T-ALL. PMID:33553159
Integrative Analyses of Genes Associated With Osteoporosis in CD16+ Monocyte. PMID:33551990
A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression. PMID:33546472
TP53 Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients. PMID:33546249
Identification of potential biomarkers associated with immune infiltration in the esophageal carcinoma tumor microenvironment. PMID:33543230
Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line. PMID:33542717
Drosophila oocyte proteome composition covaries with female mating status. PMID:33542461
Complement and coagulation cascades activation is the main pathophysiological pathway in early-onset severe preeclampsia revealed by maternal proteomics. PMID:33542402
Explainable drug sensitivity prediction through cancer pathway enrichment. PMID:33542382
High ROBO3 expression predicts poor survival in non-M3 acute myeloid leukemia. PMID:33541130
The Dystrophin Node as Integrator of Cytoskeletal Organization, Lateral Force Transmission, Fiber Stability and Cellular Signaling in Skeletal Muscle. PMID:33540575
Comparative transcriptome analyses between cultivated and wild grapes reveal conservation of expressed genes but extensive rewiring of co-expression networks. PMID:33538951
TREM-1+ Macrophages Define a Pathogenic Cell Subset in the Intestine of Crohn's Disease Patients. PMID:33537747
Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups. PMID:33536424
Identification of microRNA-16-5p and microRNA-21-5p in feces as potential noninvasive biomarkers for inflammatory bowel disease. PMID:33535181
Prediction of SARS-CoV Interaction with Host Proteins during Lung Aging Reveals a Potential Role for TRIB3 in COVID-19. PMID:33532126
A High-Throughput Method for Identifying Novel Genes That Influence Metabolic Pathways Reveals New Iron and Heme Regulation in Pseudomonas aeruginosa. PMID:33531406
The potential role of chemotaxis and the complement system in the formation and progression of thoracic aortic aneurysms inferred from the weighted gene coexpression network analysis. PMID:33531038
RUNX3 Transcript Variants Have Distinct Roles in Ovarian Carcinoma and Differently Influence Platinum Sensitivity and Angiogenesis. PMID:33530588
In silico characterization and structural modeling of bacterial metalloprotease of family M4. PMID:33528696
FoxP1 is a transcriptional repressor associated with cancer cachexia that induces skeletal muscle wasting and weakness. PMID:33527776
Molecular characterization of a marine turtle tumor epizootic, profiling external, internal and postsurgical regrowth tumors. PMID:33526843
GeneWalk identifies relevant gene functions for a biological context using network representation learning. PMID:33526072
Overexpression of NELFE contributes to gastric cancer progression via Wnt/β-catenin signaling-mediated activation of CSNK2B expression. PMID:33526068
Acid pH Strategy Adaptation through NRG1 in Ustilago maydis. PMID:33525315
Human pathways in animal models: possibilities and limitations. PMID:33524155
SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites. PMID:33524141
Robust gene coexpression networks using signed distance correlation. PMID:33523234
Analyzing the potential therapeutic mechanism of Huashi Baidu Decoction on severe COVID-19 through integrating network pharmacological methods. PMID:33520684
Tumor-intrinsic and -extrinsic (immune) gene signatures robustly predict overall survival and treatment response in high grade serous ovarian cancer patients. PMID:33520368
Identification of Common Genes and Pathways in Eight Fibrosis Diseases. PMID:33519923
Identification of Potential Diagnostic and Prognostic Biomarkers for Colorectal Cancer Based on GEO and TCGA Databases. PMID:33519906
ALDH2 deficiency induces atrial fibrillation through dysregulated cardiac sodium channel and mitochondrial bioenergetics: A multi-omics analysis. PMID:33515676
Verifying explainability of a deep learning tissue classifier trained on RNA-seq data. PMID:33514769
Survival of hypoxia-induced dormancy is not a common feature of all strains of the Mycobacterium tuberculosis complex. PMID:33514768
Transcriptomics Reveals Fast Changes in Salicylate and Jasmonate Signaling Pathways in Shoots of Carbonate-Tolerant Arabidopsis thaliana under Bicarbonate Exposure. PMID:33513755
Genes and SNPs Involved with Scrotal and Umbilical Hernia in Pigs. PMID:33513662
Chromatin-associated SUMOylation controls the transcriptional switch between plant development and heat stress responses. PMID:33511343
Metabolons, enzyme-enzyme assemblies that mediate substrate channeling, and their roles in plant metabolism. PMID:33511342
METTL3-mediated m6A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lung. PMID:33510938
Rheumatoid arthritis CD14+ monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease. PMID:33510894
Toxoplasma and Eimeria co-opt the host cFos expression for intracellular development in mammalian cells. PMID:33510872
Gene signature of children with severe respiratory syncytial virus infection. PMID:33510411
High-Density, Targeted Monitoring of Tyrosine Phosphorylation Reveals Activated Signaling Networks in Human Tumors. PMID:33509940
The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut. PMID:33509277
Tumor mutation burden in connection with immune-related survival in uterine corpus endometrial carcinoma. PMID:33509222
Stem cell transplantation rescued a primary open-angle glaucoma mouse model. PMID:33506763
Study on the Potential Mechanism of Fructus Tribuli in the Treatment of Hypertensive Vascular Remodeling Based on Network Pharmacology and Molecular Docking. PMID:33505509
Increased Expression of TICRR Predicts Poor Clinical Outcomes: A Potential Therapeutic Target for Papillary Renal Cell Carcinoma. PMID:33505430
Identification of Hub Genes Associated With Immune Infiltration and Predict Prognosis in Hepatocellular Carcinoma via Bioinformatics Approaches. PMID:33505422
Integrated Analysis of RNA-Binding Proteins Associated With the Prognosis and Immunosuppression in Squamous Cell Carcinoma of Head and Neck. PMID:33505420
circRNA circ_102049 Implicates in Pancreatic Ductal Adenocarcinoma Progression through Activating CD80 by Targeting miR-455-3p. PMID:33505218
Multi-organ proteomic landscape of COVID-19 autopsies. PMID:33503446
Development of a prognostic index based on immunogenomic landscape analysis in glioma. PMID:33503296
Identification of small proline-rich protein 1B (SPRR1B) as a prognostically predictive biomarker for lung adenocarcinoma by integrative bioinformatic analysis. PMID:33501784
Screening and identification of potential biomarkers and therapeutic drugs in melanoma via integrated bioinformatics analysis. PMID:33501609
An Autoantigen Atlas from Human Lung HFL1 Cells Offers Clues to Neurological and Diverse Autoimmune Manifestations of COVID-19. PMID:33501444
Effects of Three-Month Feeding High Fat Diets with Different Fatty Acid Composition on Myocardial Proteome in Mice. PMID:33498641
Identification of downstream signaling cascades of ACK1 and prognostic classifiers in non-small cell lung cancer. PMID:33495411
Transcriptomic characterization reveals prognostic molecular signatures of sorafenib resistance in hepatocellular carcinoma. PMID:33495404
A network pharmacology perspective for deciphering potential mechanisms of action of Solanum nigrum L. in bladder cancer. PMID:33494738
Manganese exposure in juvenile C57BL/6 mice increases glial inflammatory responses in the substantia nigra following infection with H1N1 influenza virus. PMID:33493177
Expression and prognostic analyses of SCAMPs in pancreatic adenocarcinoma. PMID:33493138
Identification of core genes for early diagnosis and the EMT modulation of ovarian serous cancer by bioinformatics perspective. PMID:33493131
Computational assessment of saikosaponins as adjuvant treatment for COVID-19: molecular docking, dynamics, and network pharmacology analysis. PMID:33492566
Molecular Diversity of Clinically Stable Human Kidney Allografts. PMID:33492376
BRAF AMP Frequently Co-occurs With IDH1/2, TP53, and ATRX Mutations in Adult Patients With Gliomas and Is Associated With Poorer Survival Than That of Patients Harboring BRAF V600E. PMID:33489866
Machine learning applications in drug development. PMID:33489002
Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren's Syndrome. PMID:33488608
Identification of Regeneration and Hub Genes and Pathways at Different Time Points after Spinal Cord Injury. PMID:33484404
Risk assessment analysis for maternal autoantibody-related autism (MAR-ASD): a subtype of autism. PMID:33483694
Correlation Between High Expression of FOXA2 and Improved Overall Survival in Ovarian Cancer Patients. PMID:33483461
SOX4 maintains the stemness of cancer cells via transcriptionally enhancing HDAC1 revealed by comparative proteomics study. PMID:33482915
Study of the active ingredients and mechanism of Sparganii rhizoma in gastric cancer based on HPLC-Q-TOF-MS/MS and network pharmacology. PMID:33479376
An across-breed validation study of 46 genetic markers in canine hip dysplasia. PMID:33478395
Interactions of Viral Proteins from Pathogenic and Low or Non-Pathogenic Orthohantaviruses with Human Type I Interferon Signaling. PMID:33478127
From Spaceflight to Mars g-Levels: Adaptive Response of A. Thaliana Seedlings in a Reduced Gravity Environment Is Enhanced by Red-Light Photostimulation. PMID:33477454
A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells. PMID:33476933
An increased burden of rare exonic variants in NRXN1 microdeletion carriers is likely to enhance the penetrance for autism spectrum disorder. PMID:33476483
Discovery and function exploration of microRNA-155 as a molecular biomarker for early detection of breast cancer. PMID:33475963
Differential gene expression in cisplatin-resistant and -sensitive testicular germ cell tumor cell lines. PMID:33473258
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. PMID:33473109
Identification of Prognostic Biomarkers and Molecular Targets Among JAK Family in Breast Cancer. PMID:33469338
Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis. PMID:33469142
Synergism of Proneurogenic miRNAs Provides a More Effective Strategy to Target Glioma Stem Cells. PMID:33466745
Loss of Motility as a Non-Lethal Mechanism for Intercolony Inhibition ("Sibling Rivalry") in Marinobacter. PMID:33466273
Protein co-expression networks identified from HOT lesions of ER+HER2-Ki-67high luminal breast carcinomas. PMID:33462336
Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells. PMID:33459596
Bioinformatics and system biology approach to identify the influences of COVID-19 on cardiovascular and hypertensive comorbidities. PMID:33458761
Serum-Derived Exosomal Proteins as Potential Candidate Biomarkers for Hepatocellular Carcinoma. PMID:33458533
Pharmacological Network Reveals the Active Mechanism of Qi-Replenishing, Spleen-Strengthening, Phlegm-Dispelling, and Blood-Nourishing Fufang on Coronary Heart Disease. PMID:33456482
Identification of a Prognostic Risk Signature of Kidney Renal Clear Cell Carcinoma Based on Regulating the Immune Response Pathway Exploration. PMID:33456463
Construction and validation of a three-microRNA signature as prognostic biomarker in patients with hepatocellular carcinoma. PMID:33456356
MRPL27 contributes to unfavorable overall survival and disease-free survival from cholangiocarcinoma patients. PMID:33456351
HMGB1 is a key factor for tamoxifen resistance and has the potential to predict the efficacy of CDK4/6 inhibitors in breast cancer. PMID:33453094
lncRNA expression profiles and associated ceRNA network analyses in epicardial adipose tissue of patients with coronary artery disease. PMID:33452392
Systematic Identification of Protein Targets of Sub5 Using Saccharomyces cerevisiae Proteome Microarrays. PMID:33451135
Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. PMID:33450205
The pioneer and differentiation factor FOXA2 is a key driver of yolk-sac tumour formation and a new biomarker for paediatric and adult yolk-sac tumours. PMID:33448076
Tracking telomere fusions through crisis reveals conflict between DNA transcription and the DNA damage response. PMID:33447828
Identification of Hub Genes as Potential Prognostic Biomarkers in Cervical Cancer Using Comprehensive Bioinformatics Analysis and Validation Studies. PMID:33447084
PDIA4 Correlates with Poor Prognosis and is a Potential Biomarker in Glioma. PMID:33447054
Late p65 nuclear translocation in glioblastoma cells indicates non-canonical TLR4 signaling and activation of DNA repair genes. PMID:33446690
Network pharmacology modeling identifies synergistic interaction of therapeutic and toxicological mechanisms for Tripterygium hypoglaucum Hutch. PMID:33446184
Multiscale Regulation of the Intervertebral Disc: Achievements in Experimental, In Silico, and Regenerative Research. PMID:33445782
Mimicking Tumor Hypoxia in Non-Small Cell Lung Cancer Employing Three-Dimensional In Vitro Models. PMID:33445709
Specific Antiproliferative Properties of Proteinaceous Toxin Secretions from the Marine Annelid Eulalia sp. onto Ovarian Cancer Cells. PMID:33445445
Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer. PMID:33445170
Genome-wide identification, characterization and transcriptional profiling of NHX-type (Na+/H+) antiporters under salinity stress in soybean. PMID:33442515
MicroRNA expression profiling after recurrent febrile seizures in rat and emerging role of miR-148a-3p/SYNJ1 axis. PMID:33441699
Multiplex gene and phenotype network to characterize shared genetic pathways of epilepsy and autism. PMID:33441621
Platelet Proteomes, Pathways, and Phenotypes as Informants of Vascular Wellness and Disease. PMID:33441027
Ceruloplasmin Deamidation in Neurodegeneration: From Loss to Gain of Function. PMID:33440850
Comparative Analysis of Transcriptome and sRNAs Expression Patterns in the Brachypodium distachyon- Magnaporthe oryzae Pathosystems. PMID:33440747
Mitochondria-related core genes and TF-miRNA-hub mrDEGs network in breast cancer. PMID:33439992
Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures. PMID:33439897
Temporal modulation of the NF-κB RelA network in response to different types of DNA damage. PMID:33438746
Profiling transcriptomic changes and signaling pathways in atopic dermatitis by integrative analyses on multiple databases. PMID:33438050
Application of graphical lasso in estimating network structure in gene set. PMID:33437755
INSR mediated by transcription factor KLF4 and DNA methylation ameliorates osteoarthritis progression via inactivation of JAK2/STAT3 signaling pathway. PMID:33437372
Artificial Intelligence in Drug Discovery: A Comprehensive Review of Data-driven and Machine Learning Approaches. PMID:33437151
Mass spectrometry-based protein-protein interaction networks for the study of human diseases. PMID:33434350
Identification of biomarkers and construction of a microRNA‑mRNA regulatory network for clear cell renal cell carcinoma using integrated bioinformatics analysis. PMID:33434215
Alternative splicing in normal and pathological human placentas is correlated to genetic variants. PMID:33433680
Revealing mechanism of Caulis Sargentodoxae for the treatment of ulcerative colitis based on network pharmacology approach. PMID:33432986
Molecular characterization of selectively vulnerable neurons in Alzheimer's disease. PMID:33432193
Exome-wide evaluation of rare coding variants using electronic health records identifies new gene-phenotype associations. PMID:33432171
Protein-protein interaction network analysis applied to DNA copy number profiling suggests new perspectives on the aetiology of Mayer-Rokitansky-Küster-Hauser syndrome. PMID:33432050
Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence. PMID:33432018
BIRC5 is a prognostic biomarker associated with tumor immune cell infiltration. PMID:33431968
Identification of the active substances and mechanisms of ginger for the treatment of colon cancer based on network pharmacology and molecular docking. PMID:33430939
Microarray expression profile of mRNAs and long noncoding RNAs and the potential role of PFK-1 in infantile hemangioma. PMID:33430906
A 9 mRNAs-based diagnostic signature for rheumatoid arthritis by integrating bioinformatic analysis and machine-learning. PMID:33430905
In Silico Characterization of Toxin-Antitoxin Systems in Campylobacter Isolates Recovered from Food Sources and Sporadic Human Illness. PMID:33430508
Role of Transportome in the Gills of Chinese Mitten Crabs in Response to Salinity Change: A Meta-Analysis of RNA-Seq Datasets. PMID:33430106
Cartilage Targets of Knee Osteoarthritis Shared by Both Genders. PMID:33430025
Exploring the Antitumor Mechanisms of Zingiberis Rhizoma Combined with Coptidis Rhizoma Using a Network Pharmacology Approach. PMID:33426081
An Integrative Computational Approach for the Prediction of Human-Plasmodium Protein-Protein Interactions. PMID:33426052
Regulator Network Analysis of Rice and Maize Yield-Related Genes. PMID:33425929
Clinicopathological Significances of Cancer Stem Cell-Associated HHEX Expression in Breast Cancer. PMID:33425911
A Proteomics Signature of Mild Hypospadias: A Pilot Study. PMID:33425810
HTRA3 Is a Prognostic Biomarker and Associated With Immune Infiltrates in Gastric Cancer. PMID:33425760
A Prognostic Microenvironment-Related Immune Signature via ESTIMATE (PROMISE Model) Predicts Overall Survival of Patients With Glioma. PMID:33425732
Comparative Expression Analysis of Stress-Inducible Candidate Genes in Response to Cold and Drought in Tea Plant [Camellia sinensis (L.) Kuntze]. PMID:33424935
A Novel Strategy for Decoding and Validating the Combination Principles of Huanglian Jiedu Decoction From Multi-Scale Perspective. PMID:33424585
SlHyPRP1 and DEA1, the multiple stress responsive eight-cysteine motif family genes of tomato (Solanum lycopersicum L.) are expressed tissue specifically, localize and interact at cytoplasm and plasma membrane in vivo. PMID:33424164
Common variants in MAEA gene contributed the susceptibility to osteoporosis in Han Chinese postmenopausal women. PMID:33423677
Expression of SARS-COV-2 cell receptor gene ACE2 is associated with immunosuppression and metabolic reprogramming in lung adenocarcinoma based on bioinformatics analyses of gene expression profiles. PMID:33422520
Biotin Proximity Labeling for Protein-Protein Interaction Discovery: The BioID Method. PMID:33421001
A Protocol for Isolation, Purification, Characterization, and Functional Dissection of Exosomes. PMID:33420988
Identification of abnormally methylated-differentially expressed genes and pathways in osteoarthritis: a comprehensive bioinformatic study. PMID:33420869
Octenidine-based hydrogel shows anti-inflammatory and protease-inhibitory capacities in wounded human skin. PMID:33420112
Resilin-mimetics as a smart biomaterial platform for biomedical applications. PMID:33420053
Multi-Omics Approach Reveals miR-SNPs Affecting Muscle Fatty Acids Profile in Nelore Cattle. PMID:33419037
Enhancement of cisplatin sensitivity in human breast cancer MCF-7 cell line through BiP and 14-3-3ζ co-knockdown. PMID:33416155
Transcriptomic landscaping of core genes and pathways of mild and severe psoriasis vulgaris. PMID:33416099
Automated Extraction of Information From Texts of Scientific Publications: Insights Into HIV Treatment Strategies. PMID:33414815
Identification of Hub Genes Associated With Development and Microenvironment of Hepatocellular Carcinoma by Weighted Gene Co-expression Network Analysis and Differential Gene Expression Analysis. PMID:33414813
HiDeF: identifying persistent structures in multiscale 'omics data. PMID:33413539
Transcriptome of nasopharyngeal samples from COVID-19 patients and a comparative analysis with other SARS-CoV-2 infection models reveal disparate host responses against SARS-CoV-2. PMID:33413422
Prediction of hub genes of Alzheimer's disease using a protein interaction network and functional enrichment analysis. PMID:33412755
Identification of novel SNPs associated with coronary artery disease and birth weight using a pleiotropic cFDR method. PMID:33411684
Integrated bioinformatic analysis of RNA binding proteins in hepatocellular carcinoma. PMID:33411682
Uncovering the mechanism of Ge-Gen-Qin-Lian decoction for treating ulcerative colitis based on network pharmacology and molecular docking verification. PMID:33409535
Machine Learning Models to Predict Primary Sites of Metastatic Cervical Carcinoma From Unknown Primary. PMID:33408743
Associations between stool micro-transcriptome, gut microbiota, and infant growth. PMID:33407969
The histone methyltransferase inhibitor A-366 enhances hemoglobin expression in erythroleukemia cells upon co-exposure with chemical inducers in culture. PMID:33407944
Integrated analyses of miRNA and mRNA profiles in leukocytes and serums in traditional Chinese medicine (TCM)-defined Pi-qi-deficiency syndrome and Pi-wei damp-heat syndrome resulting from chronic atrophic gastritis. PMID:33407671
XPF expression and its relationship with the risk and prognosis of colorectal cancer. PMID:33407486
Limited Proteolysis-Coupled Mass Spectrometry Identifies Phosphatidylinositol 4,5-Bisphosphate Effectors in Human Nuclear Proteome. PMID:33406800
Shared Blood Transcriptomic Signatures between Alzheimer's Disease and Diabetes Mellitus. PMID:33406707
Spatiotemporal analysis of human intestinal development at single-cell resolution. PMID:33406409
Bioinformatics: new tools and applications in life science and personalized medicine. PMID:33404829
Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes. PMID:33404012
New novel non-MHC genes were identified for cervical cancer with an integrative analysis approach of transcriptome-wide association study. PMID:33403041
Overexpression of TC2N is associated with poor prognosis in gastric cancer. PMID:33403038
Bioinformatics Analysis of Key Genes and Pathways of Cervical Cancer. PMID:33402836
Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease. PMID:33398182
Construction and prognostic analysis of miRNA-mRNA regulatory network in liver metastasis from colorectal cancer. PMID:33397428
Targeting Lymphotoxin Beta and Paired Box 5: a potential therapeutic strategy for soft tissue sarcoma metastasis. PMID:33397394
Functions of Essential Genes and a Scale-Free Protein Interaction Network Revealed by Structure-Based Function and Interaction Prediction for a Minimal Genome. PMID:33393786
A host-based whole genome sequencing study reveals novel risk loci associated with severity of influenza A(H1N1)pdm09 infection. PMID:33393450
Data on European seabass fed with methionine-enriched diets obtained through label free shotgun proteomics. PMID:33392368
Metabolic Signature of Articular Cartilage Following Mechanical Injury: An Integrated Transcriptomics and Metabolomics Analysis. PMID:33392255
The Large Scale Structure of Human Metabolism Reveals Resilience via Extensive Signaling Crosstalk. PMID:33391012
MYC dysfunction modulates stemness and tumorigenesis in breast cancer. PMID:33390842
Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss. PMID:33390590
Overlapping Protein Accumulation Profiles of CADASIL and CAA: Is There a Common Mechanism Driving Cerebral Small-Vessel Disease? PMID:33387456
Network machine learning maps phytochemically rich "Hyperfoods" to fight COVID-19. PMID:33386081
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks. PMID:33382968
Comprehensive Analysis of lncRNAs Related to the Prognosis of Esophageal Cancer Based on ceRNA Network and Cox Regression Model. PMID:33381546
A Novel Four-Gene Signature Associated With Immune Checkpoint for Predicting Prognosis in Lower-Grade Glioma. PMID:33381460
Risk Stratification in Acute Myeloid Leukemia Using CXCR Gene Signatures: A Bioinformatics Analysis. PMID:33381455
Identification of miRNAs as the Crosstalk in the Interaction between Neural Stem/Progenitor Cells and Endothelial Cells. PMID:33381243
Classification and Computational Analysis of Arabidopsis thaliana Sperm Cell-Specific F-Box Protein Gene 3p.AtFBP113. PMID:33381153
Single-cell transcriptomic profiling provides insights into retinal endothelial barrier properties. PMID:33380778
Feature Selection for Topological Proximity Prediction of Single-Cell Transcriptomic Profiles in Drosophila Embryo Using Genetic Algorithm. PMID:33379262
Long Non-Coding RNAs in Diffuse Large B-Cell Lymphoma. PMID:33379241
Isobaric tags for relative and absolute quantitation-based proteomics analysis of the effect of ginger oil on bisphenol A-induced breast cancer cell proliferation. PMID:33376534
Effect of let-7c on the PI3K/Akt/FoxO signaling pathway in hepatocellular carcinoma. PMID:33376529
Genome-wide prioritization reveals novel gene signatures associated with cardiotoxic effects of tyrosine kinase inhibitors. PMID:33376527
The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic β-cells. PMID:33376132
Novel RB1 and MET Gene Mutations in a Case with Bilateral Retinoblastoma Followed by Multiple Metastatic Osteosarcoma. PMID:33375764
Structural Variability, Expression Profile, and Pharmacogenetic Properties of TMPRSS2 Gene as a Potential Target for COVID-19 Therapy. PMID:33375616
MNBDR: A Module Network Based Method for Drug Repositioning. PMID:33375395
Glioblastoma CUSA Fluid Protein Profiling: A Comparative Investigation of the Core and Peripheral Tumor Zones. PMID:33374813
The Liability Threshold Model for Predicting the Risk of Cardiovascular Disease in Patients with Type 2 Diabetes: A Multi-Cohort Study of Korean Adults. PMID:33374401
A Label-Free Cellular Proteomics Approach to Decipher the Antifungal Action of DiMIQ, a Potent Indolo[2,3-b]Quinoline Agent, against Candida albicans Biofilms. PMID:33374351
Comprehensive network modeling from single cell RNA sequencing of human and mouse reveals well conserved transcription regulation of hematopoiesis. PMID:33372598
Differential alternative splicing between hepatocellular carcinoma with normal and elevated serum alpha-fetoprotein. PMID:33371894
Interaction with Ribosomal Proteins Accompanies Stress Induction of the Anticancer Metallodrug BOLD-100/KP1339 in the Endoplasmic Reticulum. PMID:33369073
An Educational Bioinformatics Project to Improve Genome Annotation. PMID:33365016
Bioinformatics Analysis of the Prognostic and Biological Significance of ZDHHC-Protein Acyltransferases in Kidney Renal Clear Cell Carcinoma. PMID:33364189
Identification of Hub Prognosis-Associated Oxidative Stress Genes in Pancreatic Cancer Using Integrated Bioinformatics Analysis. PMID:33363572
Analysis of Pan-omics Data in Human Interactome Network (APODHIN). PMID:33363571
Epigenetic Variation Analysis Leads to Biomarker Discovery in Gastric Adenocarcinoma. PMID:33363566
Systematic Analysis of Expression Profiles and Prognostic Significance for FAM83 Family in Non-small-Cell Lung Cancer. PMID:33363204
Identification of histone deacetylase genes in Dendrobium officinale and their expression profiles under phytohormone and abiotic stress treatments. PMID:33362966
Transcriptome profiling reveals Silibinin dose-dependent response network in non-small lung cancer cells. PMID:33362957
Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identifies Candidate Genes Associated With Idiopathic Pulmonary Fibrosis. PMID:33362862
Hybrid Incompatibilities and Transgressive Gene Expression Between Two Closely Related Subspecies of Drosophila. PMID:33362859
Acyl-CoA Thioesterase 8 and 11 as Novel Biomarkers for Clear Cell Renal Cell Carcinoma. PMID:33362855
Conditional Generative Adversarial Networks for Individualized Treatment Effect Estimation and Treatment Selection. PMID:33362849
Effects of In Vivo Gluten Challenge on PBMC Gene Expression Profiles in Diet Treated Celiac Disease. PMID:33362776
Longitudinal transcriptome analyses show robust T cell immunity during recovery from COVID-19. PMID:33361761
Granulocyte-Colony Stimulating Factor Reduces Cocaine-Seeking and Downregulates Glutamatergic Synaptic Proteins in Medial Prefrontal Cortex. PMID:33361463
Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1. PMID:33357424
Bioinformatics analysis identifies potential diagnostic signatures for coronary artery disease. PMID:33356708
miR-21 is upregulated, promoting fibrosis and blocking G2/M in irradiated rat cardiac fibroblasts. PMID:33354435
Multi-resolution visualization and analysis of biomolecular networks through hierarchical community detection and web-based graphical tools. PMID:33351828
The SARS-CoV-2 RNA-protein interactome in infected human cells. PMID:33349665
The impact of structural bioinformatics tools and resources on SARS-CoV-2 research and therapeutic strategies. PMID:33348379
Systematic review and meta-analysis of human transcriptomics reveals neuroinflammation, deficient energy metabolism, and proteostasis failure across neurodegeneration. PMID:33347974
Mouse Embryonic Fibroblast Adipogenic Potential: A Comprehensive Transcriptome Analysis. PMID:33345692
CXCL10 is a potential biomarker and associated with immune infiltration in human papillary thyroid cancer. PMID:33345267
Long Noncoding RNA THAP9-AS1 and TSPOAP1-AS1 Provide Potential Diagnostic Signatures for Pediatric Septic Shock. PMID:33344646
An Investigation of the Molecular Mechanisms Underlying the Analgesic Effect of Jakyak-Gamcho Decoction: A Network Pharmacology Study. PMID:33343676
Improved Detection of Potentially Pleiotropic Genes in Coronary Artery Disease and Chronic Kidney Disease Using GWAS Summary Statistics. PMID:33343632
DAB2IP modulates primary cilia formation associated with renal tumorigenesis. PMID:33341566
Single-cell atlas of the first intra-mammalian developmental stage of the human parasite Schistosoma mansoni. PMID:33339816
Tissue Engineering of Cartilage Using a Random Positioning Machine. PMID:33339388
The mRNA Binding Proteome of Proliferating and Differentiated Muscle Cells. PMID:33338663
Screening and Identification of Prognostic Tumor-Infiltrating Immune Cells and Genes of Endometrioid Endometrial Adenocarcinoma: Based on The Cancer Genome Atlas Database and Bioinformatics. PMID:33335850
The identification of co-expressed gene modules in Streptococcus pneumonia from colonization to infection to predict novel potential virulence genes. PMID:33334315
SECAT: Quantifying Protein Complex Dynamics across Cell States by Network-Centric Analysis of SEC-SWATH-MS Profiles. PMID:33333029
Deep Learning on High-Throughput Transcriptomics to Predict Drug-Induced Liver Injury. PMID:33330410
Frameshift Variant in Novel Adenosine-A1-Receptor Homolog Associated With Bovine Spastic Syndrome/Late-Onset Bovine Spastic Paresis in Holstein Sires. PMID:33329738
Multi-Approach Bioinformatics Analysis of Curated Omics Data Provides a Gene Expression Panorama for Multiple Cancer Types. PMID:33329726
Proteome-Wide Analysis of Lysine 2-Hydroxyisobutyrylation in the Phytopathogenic Fungus Botrytis cinerea. PMID:33329453
A gene expression atlas for different kinds of stress in the mouse brain. PMID:33328476
FIREWORKS: a bottom-up approach to integrative coessentiality network analysis. PMID:33328249
Identifications of Candidate Genes Significantly Associated With Rectal Cancer by Integrated Bioinformatics Analysis. PMID:33327880
Examination of Oral Squamous Cell Carcinoma and Precancerous Lesions Using Proximity Extension Assay and Salivary RNA Quantification. PMID:33327496
Identification of a Transcriptomic Prognostic Signature by Machine Learning Using a Combination of Small Cohorts of Prostate Cancer. PMID:33324443
Combining sequence and network information to enhance protein-protein interaction prediction. PMID:33323120
NF-κB Signaling Is Regulated by Fucosylation in Metastatic Breast Cancer Cells. PMID:33322811
Peptide-Based Identification of Phytophthora Isolates and Phytophthora Detection in Planta. PMID:33322721
Differential Co-Expression Analyses Allow the Identification of Critical Signalling Pathways Altered during Tumour Transformation and Progression. PMID:33322692
Immunoproteomic Analysis Reveals Novel Candidate Antigens for the Diagnosis of Paracoccidioidomycosis Due to Paracoccidioides lutzii. PMID:33322269
Functional Dependency Analysis Identifies Potential Druggable Targets in Acute Myeloid Leukemia. PMID:33321907
A splicing factor switch controls hematopoietic lineage specification of pluripotent stem cells. PMID:33319461
PLEKHG5 regulates autophagy, survival and MGMT expression in U251-MG glioblastoma cells. PMID:33318498
Biotin rescues mitochondrial dysfunction and neurotoxicity in a tauopathy model. PMID:33318181
Expression of PAWR predicts prognosis of ovarian cancer. PMID:33317551
Clustering Analysis Supports the Detection of Biological Processes Related to Autism Spectrum Disorder. PMID:33316975
Exostosin1 as a novel prognostic and predictive biomarker for squamous cell lung carcinoma: A study based on bioinformatics analysis. PMID:33314711
Protein Interaction Network Biology in Neuroscience. PMID:33314619
Identification of key microRNAs of plasma extracellular vesicles and their diagnostic and prognostic significance in melanoma. PMID:33313406
A bioinformatics analysis on the potential role of ACE2 in cardiac impairment of patients with coronavirus disease 2019. PMID:33313148
Intron retention is a robust marker of intertumoral heterogeneity in pancreatic ductal adenocarcinoma. PMID:33311498
Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy. PMID:33311497
RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability. PMID:33311452
Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans. PMID:33310865
Integrated Bioinformatics Analysis for the Screening of Associated Pathways and Therapeutic Drugs in Coronavirus Disease 2019. PMID:33309308
Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study. PMID:33308445
Multiple Feature Selection Strategies Identified Novel Cardiac Gene Expression Signature for Heart Failure. PMID:33304275
Derivation and investigation of the first human cell-based model of Beckwith-Wiedemann syndrome. PMID:33300436
Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity. PMID:33300002
Exploring the Possible Mechanism and Drug Targets of Huang-Qi-Gui-Zhi-Wu-Wu Decoction for the Treatment of Chemotherapy-Induced Peripheral Neuropathy on Network Pharmacology. PMID:33299447
A Seven-NF-κB-Related Gene Signature May Distinguish Patients with Ulcerative Colitis-Associated Colorectal Carcinoma. PMID:33299340
The functional proteome landscape of Escherichia coli. PMID:33299184
Genomic investigation of co-targeting tumor immune microenvironment and immune checkpoints in pan-cancer immunotherapy. PMID:33299118
Transcriptome profiling revealed early vascular smooth muscle cell gene activation following focal ischemic stroke in female rats - comparisons with males. PMID:33297959
In Vivo Characterization of the Toxicological Properties of DPhP, One of the Main Degradation Products of Aryl Phosphate Esters. PMID:33296241
Scanning Protein Surfaces with DNA-Encoded Libraries. PMID:33295694
Transcriptomic Analysis of circRNAs in the Peripheral Blood of Nonarteritic Anterior Ischemic Optic Neuropathy. PMID:33294447
Identification of a Functional ceRNA Network to Explore Potential Biomarkers for Hepatocellular Carcinoma. PMID:33293827
Network analysis reveals essential proteins that regulate sodium-iodide symporter expression in anaplastic thyroid carcinoma. PMID:33293661
The transcription factor TAL1 and miR-17-92 create a regulatory loop in hematopoiesis. PMID:33293632
Exploring active ingredients and function mechanisms of Ephedra-bitter almond for prevention and treatment of Corona virus disease 2019 (COVID-19) based on network pharmacology. PMID:33292385
Parthenolide inhibits the growth of non-small cell lung cancer by targeting epidermal growth factor receptor. PMID:33292235
Efficacy and Mode of Action of Mesenchymal Stem Cells in Non-Ischemic Dilated Cardiomyopathy: A Systematic Review. PMID:33291410
2-oxoglutarate-dependent dioxygenases: A renaissance in attention for ascorbic acid in plants. PMID:33290424
Applications and advancements of FT-ICR-MS for interactome studies. PMID:33289940
Improving the informativeness of Mendelian disease-derived pathogenicity scores for common disease. PMID:33288751
MRE11 Is Crucial for Malaria Parasite Transmission and Its Absence Affects Expression of Interconnected Networks of Key Genes Essential for Life. PMID:33287434
Transcriptome Remodeling in Gradual Development of Inverse Resistance between Paclitaxel and Cisplatin in Ovarian Cancer Cells. PMID:33287223
Network Pharmacology Identifies the Mechanisms of Action of Tongxie Anchang Decoction in the Treatment of Irritable Bowel Syndrome with Diarrhea Predominant. PMID:33281910
Identification of miRNA Biomarkers for Diverse Cancer Types Using Statistical Learning Methods at the Whole-Genome Scale. PMID:33281862
Elucidation of the miR164c-Guided Gene/Protein Interaction Network Controlling Seed Vigor in Rice. PMID:33281848
Quantitative Changes in the Mitochondrial Proteome of Cerebellar Synaptosomes From Preclinical Cystatin B-Deficient Mice. PMID:33281550
The Clinical Significance of Dickkopf Wnt Signaling Pathway Inhibitor Gene Family in Head and Neck Squamous Cell Carcinoma. PMID:33281184
Genome-wide DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia in the Chinese Han population. PMID:33279932
Transcriptional network modulated by the prognostic signature transcription factors and their long noncoding RNA partners in primary prostate cancer. PMID:33279858
An integrated approach to biomarker discovery reveals gene signatures highly predictive of cancer progression. PMID:33277589
Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer. PMID:33277484
Global proteomics of Ubqln2-based murine models of ALS. PMID:33277362
Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial. PMID:33274667
CovMulNet19, Integrating Proteins, Diseases, Drugs, and Symptoms: A Network Medicine Approach to COVID-19. PMID:33274348
A Network Pharmacology-Based Strategy for Unveiling the Mechanisms of Tripterygium Wilfordii Hook F against Diabetic Kidney Disease. PMID:33274236
Systematic Investigation of mRNA N 6-Methyladenosine Machinery in Primary Prostate Cancer. PMID:33273988
Beyond Melanin: Proteomics Reveals Virulence-Related Proteins in Paracoccidioides brasiliensis and Paracoccidioides lutzii Yeast Cells Grown in the Presence of L-Dihydroxyphenylalanine. PMID:33271902
Bringing New Methods to the Seed Proteomics Platform: Challenges and Perspectives. PMID:33271881
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas. PMID:33271120
On the lifetime of bioinformatics web services. PMID:33270886
Aqueous Fibronectin Correlates With Severity of Macular Edema and Visual Acuity in Patients With Branch Retinal Vein Occlusion: A Proteome Study. PMID:33270842
HDL cholesterol is associated with PBMC expression of genes involved in HDL metabolism and atherogenesis. PMID:33269026
Genome-wide analysis of HSP90 gene family in the Mediterranean olive (Olea europaea subsp. europaea) provides insight into structural patterns, evolution and functional diversity. PMID:33268931
ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies. PMID:33268892
Saccharomyces paradoxus Transcriptional Alterations in Cells of Distinct Phenotype and Viral dsRNA Content. PMID:33266158
Deep whole-genome sequencing of multiple proband tissues and parental blood reveals the complex genetic etiology of congenital diaphragmatic hernias. PMID:33263113
Gene expression profiling of corona virus microarray datasets to identify crucial targets in COVID-19 patients. PMID:33263093
Identification of Common Differentially Expressed Genes and Potential Therapeutic Targets in Ulcerative Colitis and Rheumatoid Arthritis. PMID:33262784
Genetic Polymorphism of ADORA2A Is Associated With the Risk of Epilepsy and Predisposition to Neurologic Comorbidity in Chinese Southern Children. PMID:33262686
Network and pathway expansion of genetic disease associations identifies successful drug targets. PMID:33262371
Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer. PMID:33262351
Towards a unified open access dataset of molecular interactions. PMID:33262342
Improvement of Disease Resistance in Livestock: Application of Immunogenomics and CRISPR/Cas9 Technology. PMID:33260762
Functional analysis of a novel cryptochrome gene (GbCRY1) from Ginkgo biloba. PMID:33258712
RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets. PMID:33258547
Natural variation of the cardiac transcriptome in humans. PMID:33258390
Differential gene expression analysis reveals pathways important in early post-traumatic osteoarthritis in an equine model. PMID:33256611
TET2/IDH1/2/WT1 and NPM1 Mutations Influence the RUNX1 Expression Correlations in Acute Myeloid Leukemia. PMID:33255417
Unlocking Survival Mechanisms for Metal and Oxidative Stress in the Extremely Acidophilic, Halotolerant Acidihalobacter Genus. PMID:33255299
Frequent Assembly of Chimeric Complexes in the Protein Interaction Network of an Interspecies Yeast Hybrid. PMID:33252673
Spatial Proteomic Approach to Characterize Skeletal Muscle Myofibers. PMID:33251806
Chemocentric Informatics Analysis: Dexamethasone Versus Combination Therapy for COVID-19. PMID:33251412
A Novel RNA Binding Protein-Related Prognostic Signature for Hepatocellular Carcinoma. PMID:33251144
Identification of potential mRNA panels for severe acute respiratory syndrome coronavirus 2 (COVID-19) diagnosis and treatment using microarray dataset and bioinformatics methods. PMID:33251083
A ligand-based computational drug repurposing pipeline using KNIME and Programmatic Data Access: case studies for rare diseases and COVID-19. PMID:33250934
Barley Root Proteome and Metabolome in Response to Cytokinin and Abiotic Stimuli. PMID:33250914
Multi-omics integration in biomedical research - A metabolomics-centric review. PMID:33248648
Pan-Cancer Multiomics Analysis of TC2N Gene Suggests its Important Role(s) in Tumourigenesis of Many Cancers. PMID:33247676
IRF-1 expressed in the inner cell mass of the porcine early blastocyst enhances the pluripotency of induced pluripotent stem cells. PMID:33246502
Identification and differential expression of serotransferrin and apolipoprotein A-I in the plasma of HIV-1 patients treated with first-line antiretroviral therapy. PMID:33246440
Ultra-fast scalable estimation of single-cell differentiation potency from scRNA-Seq data. PMID:33244588
Investigating the human protein-host protein interactome of SARS-CoV-2 infection in the small intestine. PMID:33244381
The Methylation Pattern for Knee and Hip Osteoarthritis. PMID:33240895
MutRank: an R shiny web-application for exploratory targeted mutual rank-based coexpression analyses integrated with user-provided supporting information. PMID:33240618
Multiple functions of TBCK protein in neurodevelopment disorders and tumors. PMID:33240423
Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor Neurons. PMID:33240324
Association of Genes Involved in the Metabolic Pathways of Amyloid-β and Tau Proteins With Sporadic Late-Onset Alzheimer's Disease in the Southern Han Chinese Population. PMID:33240075
Nod2 protects mice from inflammation and obesity-dependent liver cancer. PMID:33239685
Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis. PMID:33237970
A thorough analysis of the contribution of experimental, derived and sequence-based predicted protein-protein interactions for functional annotation of proteins. PMID:33237964
RNA-binding proteins in human genetic disease. PMID:33235359
Genes Contributing to the Unique Biology and Intrinsic Antibiotic Resistance of Enterococcus faecalis. PMID:33234689
Bioinformatics-Based Research on Key Genes and Pathways of Intervertebral Disc Degeneration. PMID:33233925
Early Transcriptomic Response to OxLDL in Human Retinal Pigment Epithelial Cells. PMID:33233417
Identification of Systems Level Molecular Signatures from Glioblastoma Multiforme Derived Extracellular Vesicles. PMID:33231813
Top-Down Proteomics of Endogenous Membrane Proteins Enabled by Cloud Point Enrichment and Multidimensional Liquid Chromatography-Mass Spectrometry. PMID:33231430
Investigation of hub genes and immune status in heart transplant rejection using endomyocardial biopsies. PMID:33230903
Identification of Long Noncoding RNAs Involved in Differentiation and Survival of Vascular Smooth Muscle Cells. PMID:33230428
Genome-wide association study of individual differences of human lymphocyte profiles using large-scale cytometry data. PMID:33230199
Wrinkle in the plan: miR-34a-5p impacts chemokine signaling by modulating CXCL10/CXCL11/CXCR3-axis in CD4+, CD8+ T cells, and M1 macrophages. PMID:33229509
Identification of contributing genes of Huntington's disease by machine learning. PMID:33228685
Phylostratic Shift of Whole-Genome Duplications in Normal Mammalian Tissues towards Unicellularity Is Driven by Developmental Bivalent Genes and Reveals a Link to Cancer. PMID:33228223
Proteomic Studies of the Biofilm Matrix including Outer Membrane Vesicles of Burkholderia multivorans C1576, a Strain of Clinical Importance for Cystic Fibrosis. PMID:33228110
Cortical morphology at birth reflects spatiotemporal patterns of gene expression in the fetal human brain. PMID:33226978
Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors. PMID:33225964
Bioinformatic analysis identifies key transcriptome signatures in temporal lobe epilepsy. PMID:33225612
Bioinformatics Analysis Reveals Diagnostic Markers and Vital Pathways Involved in Acute Coronary Syndrome. PMID:33224526
In Search of TGCT Biomarkers: A Comprehensive In Silico and Histopathological Analysis. PMID:33224314
Identification of Genetic Biomarkers for Diagnosis of Myocardial Infarction Compared with Angina Patients. PMID:33224271
Perversely expressed long noncoding RNAs can alter host response and viral proliferation in SARS-CoV-2 infection. PMID:33224264
Investigation of the Potential Mechanism Governing the Effect of the Shen Zhu San on COVID-19 by Network Pharmacology. PMID:33224256
Investigating the Multitarget Mechanism of Traditional Chinese Medicine Prescription for Cancer-Related Pain by Using Network Pharmacology and Molecular Docking Approach. PMID:33224254
Integrated analysis of a competing endogenous RNA network reveals an 11-lncRNA prognostic signature in ovarian cancer. PMID:33223503
Obesity and metabolic syndrome related macrophage promotes PD-L1 expression in TNBC through IL6/JAK/STAT pathway and can be reversed by telmisartan. PMID:33218268
Genome-Wide Scan for Five Brain Oscillatory Phenotypes Identifies a New QTL Associated with Theta EEG Band. PMID:33218114
Teratoma Growth Retardation by HDACi Treatment of the Tumor Embryonal Source. PMID:33217978
Identification of grade-related genes and construction of a robust genomic-clinicopathologic nomogram for predicting recurrence of bladder cancer. PMID:33217824
Abundance of metalloprotease FtsH12 modulates chloroplast development in Arabidopsis thaliana. PMID:33216923
Histo-molecular differentiation of renal cancer subtypes by mass spectrometry imaging and rapid proteome profiling of formalin-fixed paraffin-embedded tumor tissue sections. PMID:33216824
Phosphoproteomics reveals novel modes of function and inter-relationships among PIKKs in response to genotoxic stress. PMID:33215756
Proteomic profiling and genome-wide mapping of O-GlcNAc chromatin-associated proteins reveal an O-GlcNAc-regulated genotoxic stress response. PMID:33214551
Proteome-Scale Detection of Differential Conservation Patterns at Protein and Subprotein Levels with BLUR. PMID:33211099
Current Challenges and Opportunities in Designing Protein-Protein Interaction Targeted Drugs. PMID:33209039
The effect of hypoxia on the proteomic signature of pig adipose-derived stromal/stem cells (pASCs). PMID:33208768
8-Hydroxydaidzein, an Isoflavone from Fermented Soybean, Induces Autophagy, Apoptosis, Differentiation, and Degradation of Oncoprotein BCR-ABL in K562 Cells. PMID:33207739
A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits. PMID:33207182
DeepPheno: Predicting single gene loss-of-function phenotypes using an ontology-aware hierarchical classifier. PMID:33206638
Urinary glycoproteins associated with aggressive prostate cancer. PMID:33204318
Understanding complex dynamics of behavioral, neurochemical and transcriptomic changes induced by prolonged chronic unpredictable stress in zebrafish. PMID:33203921
Immune suppression in the early stage of COVID-19 disease. PMID:33203833
Epigenetic profiling of Italian patients identified methylation sites associated with hereditary transthyretin amyloidosis. PMID:33203445
Cancer Stem Cells and the Slow Cycling Phenotype: How to Cut the Gordian Knot Driving Resistance to Therapy in Melanoma. PMID:33202944
Arabidopsis Response to Inhibitor of Cytokinin Degradation INCYDE: Modulations of Cytokinin Signaling and Plant Proteome. PMID:33202776
Development and Comparative Evaluation of Endolysosomal Proximity Labeling-Based Proteomic Methods in Human iPSC-Derived Neurons. PMID:33201688
Mitochondrial Carriers Regulating Insulin Secretion Profiled in Human Islets upon Metabolic Stress. PMID:33198243
CD138- multiple myeloma cells express high level of CHK1 which correlated to overall survival in MM patient. PMID:33197893
RBP2GO: a comprehensive pan-species database on RNA-binding proteins, their interactions and functions. PMID:33196814
Network pharmacology evaluation of the active ingredients and potential targets of XiaoLuoWan for application to uterine fibroids. PMID:33196098
KG-COVID-19: A Framework to Produce Customized Knowledge Graphs for COVID-19 Response. PMID:33196056
Characterization of the Metabolic, Clinical and Neuropsychological Phenotype of Female Carriers of the Premutation in the X-Linked FMR1 Gene. PMID:33195422
Identification of an Immune-Related Prognostic Predictor in Hepatocellular Carcinoma. PMID:33195412
Prognostic model of invasive ductal carcinoma of the breast based on differentially expressed glycolysis-related genes. PMID:33194424
Bioinformatics Analysis Discovers Microtubular Tubulin Beta 6 Class V (TUBB6) as a Potential Therapeutic Target in Glioblastoma. PMID:33193654
Theoretical and in silico Analyses Reveal MYC as a Dynamic Network Biomarker in Colon and Rectal Cancer. PMID:33193630
Screening and Identification of Potential Biomarkers in Hepatitis B Virus-Related Hepatocellular Carcinoma by Bioinformatics Analysis. PMID:33193629
The Key Genes for Perineural Invasion in Pancreatic Ductal Adenocarcinoma Identified With Monte-Carlo Feature Selection Method. PMID:33193628
NRG1, PIP4K2A, and HTR2C as Potential Candidate Biomarker Genes for Several Clinical Subphenotypes of Depression and Bipolar Disorder. PMID:33193575
Endophyte-Promoted Phosphorus Solubilization in Populus. PMID:33193494
Identification of Immune Cell Infiltration and Immune-Related Genes in the Tumor Microenvironment of Glioblastomas. PMID:33193404
A Comprehensive Analysis of MicroRNAs in Human Osteoporosis. PMID:33193074
Integrating Pharmacology and Gut Microbiota Analysis to Explore the Mechanism of Citri Reticulatae Pericarpium Against Reserpine-Induced Spleen Deficiency in Rats. PMID:33192528
Isolation and Characterization of Multi-Protein Complexes Enriched in the K-Cl Co-transporter 2 From Brain Plasma Membranes. PMID:33192291
Data mining combined with experiments to validate CEP55 as a prognostic biomarker in colorectal cancer. PMID:33190424
Bioinformatic analysis of SMN1-ACE/ACE2 interactions hinted at a potential protective effect of spinal muscular atrophy against COVID-19-induced lung injury. PMID:33190150
Bioinformatics analysis reveals TSPAN1 as a candidate biomarker of progression and prognosis in pancreatic cancer. PMID:33188589
A conserved acetylation switch enables pharmacological control of tubby-like protein stability. PMID:33187986
DLDTI: a learning-based framework for drug-target interaction identification using neural networks and network representation. PMID:33187537
Analysis of miR-9-5p, miR-124-3p, miR-21-5p, miR-138-5p, and miR-1-3p in Glioblastoma Cell Lines and Extracellular Vesicles. PMID:33187334
Mapping the Inorganic and Proteomic Differences among Different Types of Human Teeth: A Preliminary Compositional Insight. PMID:33187273
Impact of Porcine Arterivirus, Influenza B, and Their Coinfection on Antiviral Response in the Porcine Lung. PMID:33187194
Construction and analysis of miRNA-mRNA regulatory networks in the radioresistance of nasopharyngeal carcinoma. PMID:33184596
Role of miRNAs in Sigmoid Colon Cancer: A Search for Potential Biomarkers. PMID:33182525
Establishment of immune prognostic signature and analysis of prospective molecular mechanisms in childhood osteosarcoma patients. PMID:33181717
FunRes: resolving tissue-specific functional cell states based on a cell-cell communication network model. PMID:33179736
A Study on the Mechanism of Milkvetch Root in the Treatment of Diabetic Nephropathy Based on Network Pharmacology. PMID:33178322
Regulation of GABAA and 5-HT Receptors Involved in Anxiolytic Mechanisms of Jujube Seed: A System Biology Study Assisted by UPLC-Q-TOF/MS and RT-qPCR Method. PMID:33178009
Plant resistome profiling in evolutionary old bog vegetation provides new clues to understand emergence of multi-resistance. PMID:33177608
SARS-CoV-2 receptor is co-expressed with elements of the kinin-kallikrein, renin-angiotensin and coagulation systems in alveolar cells. PMID:33177594
Persistent epigenetic reprogramming of sweet taste by diet. PMID:33177090
si-SNHG5-FOXF2 inhibits TGF-β1-induced fibrosis in human primary endometrial stromal cells by the Wnt/β-catenin signalling pathway. PMID:33176855
High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers. PMID:33176066
Using mRNA deep sequencing to analyze differentially expressed genes during Panax notoginseng saponin treatment of ischemic stroke. PMID:33173991
Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality. PMID:33173868
A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research. PMID:33173863
Metabolic pathways underlying GATA6 regulating Trastuzumab resistance in Gastric Cancer cells based on untargeted metabolomics. PMID:33173435
Tripartite-motif family genes associated with cancer stem cells affect tumor progression and can assist in the clinical prognosis of kidney renal clear cell carcinoma. PMID:33173411
Lung transcriptome of a COVID-19 patient and systems biology predictions suggest impaired surfactant production which may be druggable by surfactant therapy. PMID:33173052
Droplet Digital PCR Analysis of Liquid Biopsy Samples Unveils the Diagnostic Role of hsa-miR-133a-3p and hsa-miR-375-3p in Oral Cancer. PMID:33172167
Identification of New Genetic Clusters in Glioblastoma Multiforme: EGFR Status and ADD3 Losses Influence Prognosis. PMID:33172155
Transcriptomic Analysis Reveals Candidate Genes Responsive to Sclerotinia scleroterum and Cloning of the Ss-Inducible Chitinase Genes in Morus laevigata. PMID:33171780
Deciphering cell-cell interactions and communication from gene expression. PMID:33168968
Oncolytic Reovirus (pelareorep) Induces Autophagy in KRAS-mutated Colorectal Cancer. PMID:33168658
Anti-Influenza Activity of the Ribonuclease Binase: Cellular Targets Detected by Quantitative Proteomics. PMID:33167434
The Interplay between Cancer Biology and the Endocannabinoid System-Significance for Cancer Risk, Prognosis and Response to Treatment. PMID:33167409
High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive patients. PMID:33166788
COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics. PMID:33166390
EpiGraphDB: a database and data mining platform for health data science. PMID:33165574
Tumorigenesis-related key genes in adolescents and young adults with HR(+)/HER2(-) breast cancer. PMID:33165441
Nearly Half of TP53 Germline Variants Predicted To Be Pathogenic in Patients With Osteosarcoma Are De Novo: A Report From the Children's Oncology Group. PMID:33163847
Genome-wide analysis of PHD finger gene family and identification of potential miRNA and their PHD finger gene specific targets in Oryza sativa indica. PMID:33163736
Comparative Transcriptome Analysis Reveals the Protective Mechanism of Glycyrrhinic Acid for Deoxynivalenol-Induced Inflammation and Apoptosis in IPEC-J2 Cells. PMID:33163144
Proteomic analysis of bladder biopsies from interstitial cystitis/bladder pain syndrome patients with and without Hunner's lesions reveals differences in expression of inflammatory and structural proteins. PMID:33160333
Avian phenotypic convergence is subject to low genetic constraints based on genomic evidence. PMID:33160317
Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines. PMID:33157050
Coordinate Regulation of Ribosome and tRNA Biogenesis Controls Hypoxic Injury and Translation. PMID:33157031
TCRD and Pharos 2021: mining the human proteome for disease biology. PMID:33156327
Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation. PMID:33155827
Autofluorescence-based sorting removes senescent cells from mesenchymal stromal cell cultures. PMID:33154552
Analysis of transcriptional modules during human fibroblast ageing. PMID:33154459
Examining Sex Differences in the Human Placental Transcriptome During the First Fetal Androgen Peak. PMID:33150487
Constitution of a comprehensive phytochemical profile and network pharmacology based investigation to decipher molecular mechanisms of Teucrium polium L. in the treatment of type 2 diabetes mellitus. PMID:33150068
Discovering the Molecular Determinants of Phaeobacter inhibens Susceptibility to Phaeobacter Phage MD18. PMID:33148823
Changes in DNA methylation profiles of myalgic encephalomyelitis/chronic fatigue syndrome patients reflect systemic dysfunctions. PMID:33148325
Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells. PMID:33147445
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection. PMID:33147444
The interactome of multifunctional HAX1 protein suggests its role in the regulation of energy metabolism, de-aggregation, cytoskeleton organization and RNA-processing. PMID:33146709
Finding a Needle in a Haystack: Proteomics in Heart Failure. PMID:33145466
Regulation of Canonical Oncogenic Signaling Pathways in Cancer via DNA Methylation. PMID:33143142
Whole-Transcriptome Sequencing-Based Analysis of DAZL and Its Interacting Genes during Germ Cells Specification and Zygotic Genome Activation in Chickens. PMID:33142918
FAM188B Expression Is Critical for Cell Growth via FOXM1 Regulation in Lung Cancer. PMID:33142744
Transcriptome analysis of turkey (Meleagris gallopavo) reproductive tract revealed key pathways regulating spermatogenesis and post-testicular sperm maturation. PMID:33142529
Network pharmacology and molecular docking analyses on Lianhua Qingwen capsule indicate Akt1 is a potential target to treat and prevent COVID-19. PMID:33140889
Extraction and Integration of Genetic Networks from Short-Profile Omic Data Sets. PMID:33137869
Differential transcript usage in the Parkinson's disease brain. PMID:33137089
Prognostic Prediction Using a Stemness Index-Related Signature in a Cohort of Gastric Cancer. PMID:33134315
Genome-wide methylation profiles in monozygotic twins with discordance for ovarian carcinoma. PMID:33133257
Exploration of Sorafenib Influences on Gene Expression of Hepatocellular Carcinoma. PMID:33133165
A Systems Biology Approach to Identifying a Master Regulator That Can Transform the Fast Growing Cellular State to a Slowly Growing One in Early Colorectal Cancer Development Model. PMID:33133158
Development and Validation of Nine-RNA Binding Protein Signature Predicting Overall Survival for Kidney Renal Clear Cell Carcinoma. PMID:33133154
Plasma Proteome Responses in Salmonid Fish Following Immunization. PMID:33133099
TREAP: A New Topological Approach to Drug Target Inference. PMID:33129831
IHP-PING-generating integrated human protein-protein interaction networks on-the-fly. PMID:33129201
Upregulation of miR-9 and miR-193b over human Th17 cell differentiation. PMID:33128433
An in-silico method leads to recognition of hub genes and crucial pathways in survival of patients with breast cancer. PMID:33128008
Network-based machine learning in colorectal and bladder organoid models predicts anti-cancer drug efficacy in patients. PMID:33127883
Potential SARS-CoV-2 interactions with proteins involved in trophoblast functions - An in-silico study. PMID:33126048
Radiosensitizing effects of c‑myc gene knockdown‑induced G2/M phase arrest by intrinsic stimuli via the mitochondrial signaling pathway. PMID:33125136
Reactivity-Based Probe of the Iron(II)-Dependent Interactome Identifies New Cellular Modulators of Ferroptosis. PMID:33124817
Genetic alteration and clinical significance of SUMOylation regulators in multiple cancer types. PMID:33123273
Molecular Targets and Pathways Contributing to the Effects of Wenxin Keli on Atrial Fibrillation Based on a Network Pharmacology Approach. PMID:33123211
Automatic Gene Function Prediction in the 2020's. PMID:33120976
The MemMoRF database for recognizing disordered protein regions interacting with cellular membranes. PMID:33119751
[Spindle assembly checkpoint complex-related genes TTK and MAD2L1 are over-expressed in lung adenocarcinoma: a big data and bioinformatics analysis]. PMID:33118511
RNA Profiling Reveals a Common Mechanism of Histone Gene Downregulation and Complementary Effects for Radioprotectants in Response to Ionizing Radiation. PMID:33117095
Comprehensive Evaluation of Endocytosis-Associated Protein SCAMP3 in Hepatocellular Carcinoma. PMID:33116758
Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart. PMID:33116222
Proteomic Profiling of Two Distinct Populations of Extracellular Vesicles Isolated from Human Seminal Plasma. PMID:33114768
Dual Effect of Soloxolone Methyl on LPS-Induced Inflammation In Vitro and In Vivo. PMID:33114200
Identification of Molecular Network Associated with Neuroprotective Effects of Yashtimadhu (Glycyrrhiza glabra L.) by Quantitative Proteomics of Rotenone-Induced Parkinson's Disease Model. PMID:33110989
Development of a novel immune-related genes prognostic signature for osteosarcoma. PMID:33110201
WNT Signaling Driven by R-spondin 1 and LGR6 in High-grade Serous Ovarian Cancer. PMID:33109540
Regional protein expression changes within the left ventricle in a mouse model of dyssynchronous and resynchronized heart failure. PMID:33108709
Plasmodium DEH is ER-localized and crucial for oocyst mitotic division during malaria transmission. PMID:33106323
SMART: recent updates, new developments and status in 2020. PMID:33104802
Determinants of correlated expression of transcription factors and their target genes. PMID:33104784
Computational Identification of Human Biological Processes and Protein Sequence Motifs Putatively Targeted by SARS-CoV-2 Proteins Using Protein-Protein Interaction Networks. PMID:33103435
Downregulation of Keap1 Confers Features of a Fasted Metabolic State. PMID:33103077
FGF2 Affects Parkinson's Disease-Associated Molecular Networks Through Exosomal Rab8b/Rab31. PMID:33101391
Integrated Analyses of Mouse Stem Cell Transcriptomes Provide Clues for Stem Cell Maintenance and Transdifferentiation. PMID:33101382
Systematic Identification of Hub Genes in Placenta Accreta Spectrum Based on Integrated Transcriptomic and Proteomic Analysis. PMID:33101378
Comprehensive Atlas of Wheat (Triticum aestivum L.) AUXIN RESPONSE FACTOR Expression During Male Reproductive Development and Abiotic Stress. PMID:33101350
SAMHD1 as the Potential Link Between SARS-CoV-2 Infection and Neurological Complications. PMID:33101175
A bioinformatics analysis to identify novel biomarkers for prognosis of pulmonary tuberculosis. PMID:33099324
Alternative genomic diagnoses for individuals with a clinical diagnosis of Dubowitz syndrome. PMID:33098347
Lung gene expression signatures suggest pathogenic links and molecular markers for pulmonary tuberculosis, adenocarcinoma and sarcoidosis. PMID:33097805
New Insights in Saccharomyces cerevisiae Response to the Cyanotoxin Microcystin-LR, Revealed by Proteomics and Gene Expression. PMID:33096888
High-Resolution Crystal Structure of Chloroplastic Ribose-5-Phosphate Isomerase from Chlamydomonas reinhardtii-An Enzyme Involved in the Photosynthetic Calvin-Benson Cycle. PMID:33096784
SON and SRRM2 are essential for nuclear speckle formation. PMID:33095160
Allogenic stem cell transplant-associated acute graft versus host disease: a computational drug discovery text mining approach using oral and gut microbiome signatures. PMID:33094358
Identification of DHX9 as a cell cycle regulated nucleolar recruitment factor for CIZ1. PMID:33093612
Maximized quantitative phosphoproteomics allows high confidence dissection of the DNA damage signaling network. PMID:33093574
Early changes in tear film protein profiles after femtosecond LASIK surgery. PMID:33088244
Late first trimester circulating microparticle proteins predict the risk of preeclampsia < 35 weeks and suggest phenotypic differences among affected cases. PMID:33087742
Endogenous retroviruses drive KRAB zinc-finger protein family expression for tumor suppression. PMID:33087347
Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network. PMID:33087039
Interferon-Mediated Long Non-Coding RNA Response in Macrophages in the Context of HIV. PMID:33086748
Slow-Freezing Cryopreservation Ensures High Ovarian Tissue Quality Followed by In Vivo and In Vitro Methods and Is Safe for Fertility Preservation. PMID:33086522
A Bioinformatic Pipeline Places STAT5A as a miR-650 Target in Poorly Differentiated Aggressive Breast Cancer. PMID:33086498
Comparative transcriptomics reveals hidden issues in the plant response to arthropod herbivores. PMID:33085192
OGEE v3: Online GEne Essentiality database with increased coverage of organisms and human cell lines. PMID:33084874
BastionHub: a universal platform for integrating and analyzing substrates secreted by Gram-negative bacteria. PMID:33084862
Genome-wide identification of Streptococcus sanguinis fitness genes in human serum and discovery of potential selective drug targets. PMID:33084151
Identification of hub genes and small molecule therapeutic drugs related to breast cancer with comprehensive bioinformatics analysis. PMID:33083112
Differentially expressed transcripts and associated protein pathways in basilar artery smooth muscle cells of the high-salt intake-induced hypertensive rat. PMID:33083107
Unveiling the effect of dietary essential oils supplementation in Sparus aurata gills and its efficiency against the infestation by Sparicotyle chrysophrii. PMID:33082387
C-tag TNF: a reporter system to study TNF shedding. PMID:33082141
Comparative Study of Pine Reference Genomes Reveals Transposable Element Interconnected Gene Networks. PMID:33081418
Common gene signatures and key pathways in hypopharyngeal and esophageal squamous cell carcinoma: Evidence from bioinformatic analysis. PMID:33080677
Identification of a competing endogenous RNA axis related to gastric cancer. PMID:33080572
A streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics. PMID:33077710
A Genome-Wide RNAi Screen for Enhancers of a Germline Tumor Phenotype Caused by Elevated GLP-1/Notch Signaling in Caenorhabditis elegans. PMID:33077477
Discovering the molecular differences between right- and left-sided colon cancer using machine learning methods. PMID:33076847
Genome-wide identification of ATP binding cassette (ABC) transporter and heavy metal associated (HMA) gene families in flax (Linum usitatissimum L.). PMID:33076828
KIR+ CD8+ T Lymphocytes in Cancer Immunosurveillance and Patient Survival: Gene Expression Profiling. PMID:33076479
CEN-tools: an integrative platform to identify the contexts of essential genes. PMID:33073517
Human shelterin protein POT1 prevents severe telomere instability induced by homology-directed DNA repair. PMID:33073402
SP_0916 Is an Arginine Decarboxylase That Catalyzes the Synthesis of Agmatine, Which Is Critical for Capsule Biosynthesis in Streptococcus pneumoniae. PMID:33072045
Social status and ejaculate composition in the house mouse. PMID:33070725
IL-4-BATF signaling directly modulates IL-9 producing mucosal mast cell (MMC9) function in experimental food allergy. PMID:33069715
BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming. PMID:33067418
Distinct Pattern of Endoplasmic Reticulum Protein Processing and Extracellular Matrix Proteins in Functioning and Silent Corticotroph Pituitary Adenomas. PMID:33066652
Identification of Inflammatory and Disease-Associated Plasma Proteins that Associate with Intake of Added Sugar and Sugar-Sweetened Beverages and Their Role in Type 2 Diabetes Risk. PMID:33066363
Suppression of Inflammatory Cytokines Expression with Bitter Melon (Momordica Charantia) in TNBS-instigated Ulcerative Colitis. PMID:33062594
The nine ADAMs family members serve as potential biomarkers for immune infiltration in pancreatic adenocarcinoma. PMID:33062410
Identification of G2 and S Phase-Expressed-1 as a Potential Biomarker in Patients with Prostate Cancer. PMID:33061616
Biomarker exploration of microRNA-203 as a promising substrate for predicting poor survival outcome in colorectal cancer. PMID:33059609
Study of the differentially abundant proteins among Leishmania amazonensis, L. braziliensis, and L. infantum. PMID:33057350
Genome wide in-silico miRNA and target network prediction from stress responsive Horsegram (Macrotyloma uniflorum) accessions. PMID:33057204
De novo transcriptome analysis of the critically endangered alpine Himalayan herb Nardostachys jatamansi reveals the biosynthesis pathway genes of tissue-specific secondary metabolites. PMID:33057076
A strategy to incorporate prior knowledge into correlation network cutoff selection. PMID:33056991
The support of genetic evidence for cardiovascular risk induced by antineoplastic drugs. PMID:33055159
smORFunction: a tool for predicting functions of small open reading frames and microproteins. PMID:33054771
Platelet proteome and function in X-linked thrombocytopenia with thalassemia and <i>in silico</i> comparisons with gray platelet syndrome. PMID:33054111
Differentially Expressed Proteins in Intra Synovial Compared to Extra Synovial Flexor Tendon Grafts in a Rabbit Tendon Transplantation Model. PMID:33053838
POC1A acts as a promising prognostic biomarker associated with high tumor immune cell infiltration in gastric cancer. PMID:33052878
Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice. PMID:33052221
Weighted gene coexpression network analysis identifies the key role associated with acute coronary syndrome. PMID:33052139
Identification of potential key genes and miRNAs involved in Hepatoblastoma pathogenesis and prognosis. PMID:33051830
Predicting candidate genes from phenotypes, functions and anatomical site of expression. PMID:33051643
Spinal cord stimulation using differential target multiplexed programming modulates neural cell-specific transcriptomes in an animal model of neuropathic pain. PMID:33050770
Semantic similarity and machine learning with ontologies. PMID:33049044
Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling. PMID:33046706
Epigenomic landscape of enhancer elements during Hydra head organizer formation. PMID:33046126
Quantitative Proteomic Analysis of Porcine Intestinal Epithelial Cells Infected with Porcine Deltacoronavirus Using iTRAQ-Coupled LC-MS/MS. PMID:33045833
Protein anabolism is key to long-term survival in high-grade serous ovarian cancer. PMID:33045680
Screening of autophagy genes as prognostic indicators for glioma patients. PMID:33042422
Analysis of mesenchymal stem cell proteomes in situ in the ischemic heart. PMID:33042285
Proteomic Analysis of Atrial Appendages Revealed the Pathophysiological Changes of Atrial Fibrillation. PMID:33041871
In Silico Prediction of Molecular Targets of Astragaloside IV for Alleviation of COVID-19 Hyperinflammation by Systems Network Pharmacology and Bioinformatic Gene Expression Analysis. PMID:33041797
KALRN mutations promote antitumor immunity and immunotherapy response in cancer. PMID:33037113
Identifying Differentially Expressed MicroRNAs, Target Genes, and Key Pathways Deregulated in Patients with Liver Diseases. PMID:33036164
Genome-wide effects of the antimicrobial peptide apidaecin on translation termination in bacteria. PMID:33031031
A New Prognostic Risk Model Based on PPAR Pathway-Related Genes in Kidney Renal Clear Cell Carcinoma. PMID:33029112
The Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Pan-Cancer. PMID:33029111
Investigating the mechanism of ShuFeng JieDu capsule for the treatment of novel Coronavirus pneumonia (COVID-19) based on network pharmacology. PMID:33029094
Compartment-specific transcriptomics of ozone-exposed murine lungs reveals sex- and cell type-associated perturbations relevant to mucoinflammatory lung diseases. PMID:33026818
A Systems Biology Workflow for Drug and Vaccine Repurposing: Identifying Small-Molecule BCG Mimics to Reduce or Prevent COVID-19 Mortality. PMID:33025261
Evaluation of the potential role of long non-coding RNA LINC00961 in luminal breast cancer: a case-control and systems biology study. PMID:33024416
TOP2A and CENPF are synergistic master regulators activated in cervical cancer. PMID:33023625
Transcriptome Analyses and Antioxidant Activity Profiling Reveal the Role of a Lignin-Derived Biostimulant Seed Treatment in Enhancing Heat Stress Tolerance in Soybean. PMID:33023253
Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence. PMID:33023155
Molecular Characterization, Protein-Protein Interaction Network, and Evolution of Four Glutathione Peroxidases from Tetrahymena thermophila. PMID:33023127
Urine recirculation prolongs normothermic kidney perfusion via more optimal metabolic homeostasis-a proteomics study. PMID:33021021
Immunomodulatory and Antioxidative potentials of adipose-derived Mesenchymal stem cells isolated from breast versus abdominal tissue: a comparative study. PMID:33020894
Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson's disease patients. PMID:33017301
TYROBP is a potential prognostic biomarker of clear cell renal cell carcinoma. PMID:33015999
Identification of Key Genes in Gastric Cancer by Bioinformatics Analysis. PMID:33015179
The Role of Wnt/β-Catenin Pathway Mediators in Aortic Valve Stenosis. PMID:33015048
Comprehensive Analysis of Prognostic Value and Immune Infiltration of Chromobox Family Members in Colorectal Cancer. PMID:33014884
Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19. PMID:33013872
CFTR Modulator Therapy Enhances Peripheral Blood Monocyte Contributions to Immune Responses in People With Cystic Fibrosis. PMID:33013356
Localization of CDR2L and CDR2 in paraneoplastic cerebellar degeneration. PMID:33009713
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate. PMID:33009401
Selection for Resistance to a Glyphosate-Containing Herbicide in Salmonella enterica Does Not Result in a Sustained Activation of the Tolerance Response or Increased Cross-Tolerance and Cross-Resistance to Clinically Important Antibiotics. PMID:33008821
Coding transcriptome analyses reveal altered functions underlying immunotolerance of PEG-fused rat sciatic nerve allografts. PMID:33008419
Integrated analysis identifies a pathway-related competing endogenous RNA network in the progression of pancreatic cancer. PMID:33008376
Translating Biomarkers of Cholangiocarcinoma for Theranosis: A Systematic Review. PMID:33007872
Proteomics-Based Identification of DUB Substrates Using Selective Inhibitors. PMID:33007217
Summary-data-based Mendelian randomization prioritizes potential druggable targets for multiple sclerosis. PMID:33005893
Identification of NUF2 and FAM83D as potential biomarkers in triple-negative breast cancer. PMID:33005492
The Genetic Architecture of Post-Zygotic Reproductive Isolation Between Anopheles coluzzii and An. quadriannulatus. PMID:33005168
BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A. PMID:33001583
Gene coexpression network analysis reveals a novel metabolic mechanism of Clostridium acetobutylicum responding to phenolic inhibitors from lignocellulosic hydrolysates. PMID:32999686
Defining the proteolytic landscape during enterovirus infection. PMID:32997711
Rewiring of growth-dependent transcription regulation by a point mutation in region 1.1 of the housekeeping σ factor. PMID:32997144
Clearance of senescent cells during cardiac ischemia-reperfusion injury improves recovery. PMID:32996233
Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin. PMID:32994467
Transcriptomic analysis reveals dynamic molecular changes in skin induced by mechanical forces secondary to tissue expansion. PMID:32994433
Genome Profiling for Aflatoxin B1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B1-Associated DNA Damage. PMID:32994210
iTRAQ-based comparative proteomic analysis of differences in the protein profiles of stems and leaves from two alfalfa genotypes. PMID:32993512
Dynamics of a Protein Interaction Network Associated to the Aggregation of polyQ-Expanded Ataxin-1. PMID:32992839
Mutations disrupting neuritogenesis genes confer risk for cerebral palsy. PMID:32989326
An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease. PMID:32989324
Expression analysis of mammalian mitochondrial ribosomal protein genes. PMID:32987154
Transcriptomic analysis reveals gender differences in gene expression profiling of the hypothalamus of rhesus macaque with aging. PMID:32986013
Integrated Microarray and RNAseq Transcriptomic Analysis of Retinal Pigment Epithelium/Choroid in Age-Related Macular Degeneration. PMID:32984320
Mutant Proteomics of Lung Adenocarcinomas Harboring Different EGFR Mutations. PMID:32983988
Genome-Wide Identification of Dickeya solani Transcriptional Units Up-Regulated in Response to Plant Tissues From a Crop-Host Solanum tuberosum and a Weed-Host Solanum dulcamara. PMID:32983224
Inactivation of the Caenorhabditis elegans RNF-5 E3 ligase promotes IRE-1-independent ER functions. PMID:32981418
A Structurally Novel Lipoyl Synthase in the Hyperthermophilic Archaeon Thermococcus kodakarensis. PMID:32978128
Participation of HHIP Gene Variants in COPD Susceptibility, Lung Function, and Serum and Sputum Protein Levels in Women Exposed to Biomass-Burning Smoke. PMID:32977420
DIGGER: exploring the functional role of alternative splicing in protein interactions. PMID:32976589
miR-19a-3p Functions as an Oncogene by Regulating FBXO32 Expression in Multiple Myeloma. PMID:32975519
Integrated regulatory models for inference of subtype-specific susceptibilities in glioblastoma. PMID:32974985
Systemic Expression Analysis Reveals Prognostic Significance of WIPI3 in Hepatocellular Carcinoma. PMID:32973867
A proteomic repertoire of autoantigens identified from the classic autoantibody clinical test substrate HEp-2 cells. PMID:32973414
Coordinated analysis of exon and intron data reveals novel differential gene expression changes. PMID:32973253
Identification of key genes and functions of circulating tumor cells in multiple cancers through bioinformatic analysis. PMID:32972417
HLA-DPA1 gene is a potential predictor with prognostic values in multiple myeloma. PMID:32972413
Bioinformatics analysis and experimental validation of TTK as a biomarker for prognosis in non-small cell lung cancer. PMID:32969465
An immune-related gene signature for determining Ewing sarcoma prognosis based on machine learning. PMID:32968877
Genome Wide Analysis Points towards Subtype-Specific Diseases in Different Genetic Forms of Amyotrophic Lateral Sclerosis. PMID:32967368
Identifying Risk Genes and Interpreting Pathogenesis for Parkinson's Disease by a Multiomics Analysis. PMID:32967142
SARS-CoV-2 and the possible connection to ERs, ACE2, and RAGE: Focus on susceptibility factors. PMID:32965736
Light-regulated allosteric switch enables temporal and subcellular control of enzyme activity. PMID:32965214
MicroRNA-Related Prognosis Biomarkers from High-Throughput Sequencing Data of Colorectal Cancer. PMID:32964043
Identification of hub genes associated with esophageal cancer progression using bioinformatics analysis. PMID:32963620
High ADAMTS18 expression is associated with poor prognosis in stomach adenocarcinoma. PMID:32963617
Influence of platelet storage time on human platelet lysates and platelet lysate-expanded mesenchymal stromal cells for bone tissue engineering. PMID:32962723
Harnessing the Secretome of Mesenchymal Stromal Cells for Traumatic Spinal Cord Injury: Multicell Comparison and Assessment of In Vivo Efficacy. PMID:32962528
The Association between Periodontitis and Human Colorectal Cancer: Genetic and Pathogenic Linkage. PMID:32962181
Zoledronic Acid Abrogates Restraint Stress-Induced Macrophage Infiltration, PDGF-AA Expression, and Ovarian Cancer Growth. PMID:32962103
Effects of Glycyrrhizin on Multi-Drug Resistant Pseudomonas aeruginosa. PMID:32962036
Predicting gene regulatory networks from cell atlases. PMID:32958603
Knockdown of SAR1B suppresses proliferation and induces apoptosis of RKO colorectal cancer cells. PMID:32952655
In silico prediction and validation of potential therapeutic genes in pancreatic β-cells associated with type 2 diabetes. PMID:32952650
Comprehensive analysis of ubiquitin-specific protease 1 reveals its importance in hepatocellular carcinoma. PMID:32951278
Cortical Transcriptomic Alterations in Association With Appetitive Neuropeptides and Body Mass Index in Posttraumatic Stress Disorder. PMID:32951025
Network pharmacology analysis of the therapeutic mechanisms of the traditional Chinese herbal formula Lian Hua Qing Wen in Corona virus disease 2019 (COVID-19), gives fundamental support to the clinical use of LHQW. PMID:32949888
Bioinformatics Data Mining Repurposes the JAK2 (Janus Kinase 2) Inhibitor Fedratinib for Treating Pancreatic Ductal Adenocarcinoma by Reversing the KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog)-Driven Gene Signature. PMID:32947833
Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development. PMID:32946788
Prognostic significance of abnormal matrix collagen remodeling in colorectal cancer based on histologic and bioinformatics analysis. PMID:32945508
Dataset on amelogenesis-related genes variants (ENAM and ENAM interacting genes) and on human leukocyte antigen alleles (DQ2 and DQ8) distribution in children with and without molar-incisor hypomineralisation (MIH). PMID:32944598
Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake. PMID:32944194
Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles. PMID:32944174
Exploring the effect of nsSNPs in human YPEL3 gene in cellular senescence. PMID:32943700
Global reprogramming of virulence and antibiotic resistance in Pseudomonas aeruginosa by a single nucleotide polymorphism in elongation factor, fusA1. PMID:32943550
FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2. PMID:32943107
Xylella fastidiosa subsp. pauca Strains Fb7 and 9a5c from Citrus Display Differential Behavior, Secretome, and Plant Virulence. PMID:32942709
Transcriptomic analysis of cyanobacterial alkane overproduction reveals stress-related genes and inhibitors of lipid droplet formation. PMID:32941127
Perivascular Secretome Influences Hematopoietic Stem Cell Maintenance in a Gelatin Hydrogel. PMID:32939609
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion. PMID:32939090
Methods for Enrichment and Assignment of N-Acetylglucosamine Modification Sites. PMID:32938750
Analyzing Gene Expression Profiles from Ataxia and Spasticity Phenotypes to Reveal Spastic Ataxia Related Pathways. PMID:32937819
Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells. PMID:32937131
Immunotyping of tumor-infiltrating lymphocytes in triple-negative breast cancer and genetic characterization. PMID:32934708
Determining the Molecular Background of Endometrial Receptivity in Adenomyosis. PMID:32933042
Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism. PMID:32931754
Binding of raloxifene to human complement fragment 5a (hC5a): a perspective on cytokine storm and COVID19. PMID:32930050
Deciphering the Plasma Proteome of Type 2 Diabetes. PMID:32928870
Exercise immunology: Future directions. PMID:32928447
GhCIPK6a increases salt tolerance in transgenic upland cotton by involving in ROS scavenging and MAPK signaling pathways. PMID:32928106
MasterPATH: network analysis of functional genomics screening data. PMID:32928103
Association of Phosphatidylinositol-Specific Phospholipase C with Calcium-Induced Biomineralization in the Coccolithophore Emiliania huxleyi. PMID:32927844
Chitinase Gene Positively Regulates Hypersensitive and Defense Responses of Pepper to Colletotrichum acutatum Infection. PMID:32927746
BRD4/8/9 are prognostic biomarkers and associated with immune infiltrates in hepatocellular carcinoma. PMID:32927435
Carbonic Anhydrase 4 serves as a Clinicopathological Biomarker for Outcomes and Immune Infiltration in Renal Cell Carcinoma, Lower Grade Glioma, Lung Adenocarcinoma and Uveal Melanoma. PMID:32922550
Exploring the Role of Chemokine Receptor 6 (Ccr6) in the BXD Mouse Model of Gulf War Illness. PMID:32922257
An algorithm to quantify intratumor heterogeneity based on alterations of gene expression profiles. PMID:32917965
Identification of the Wallenda JNKKK as an Alk suppressor reveals increased competitiveness of Alk-expressing cells. PMID:32917927
Label-free quantitative proteomic analysis of gingival crevicular fluid to identify potential early markers for root resorption. PMID:32917196
Gene Expression Changes in the Ventral Tegmental Area of Male Mice with Alternative Social Behavior Experience in Chronic Agonistic Interactions. PMID:32917038
Overexpression of α-Synuclein Reorganises Growth Factor Profile of Human Astrocytes. PMID:32914394
Identification of Modulated MicroRNAs Associated with Breast Cancer, Diet, and Physical Activity. PMID:32911851
Identification of microRNA-451a as a Novel Circulating Biomarker for Colorectal Cancer Diagnosis. PMID:32908896
Development of an Immune Infiltration-Related Eight-Gene Prognostic Signature in Colorectal Cancer Microenvironment. PMID:32908876
Identification of Key mRNAs and lncRNAs in Neonatal Sepsis by Gene Expression Profiling. PMID:32908583
Mining of prognosis-related genes in cervical squamous cell carcinoma immune microenvironment. PMID:32904067
Overexpressed Pseudogene HLA-DPB2 Promotes Tumor Immune Infiltrates by Regulating HLA-DPB1 and Indicates a Better Prognosis in Breast Cancer. PMID:32903535
iTRAQ‑based proteomic analysis reveals potential regulatory networks in dust mite‑related asthma treated with subcutaneous allergen immunotherapy. PMID:32901873
A role for microRNAs in the epigenetic control of sexually dimorphic gene expression in the human placenta. PMID:32901510
Pre-symptomatic modified phytohormone profile is associated with lower phytoplasma titres in an Arabidopsis seor1ko line. PMID:32901060
Investigating the Role of Telomere and Telomerase Associated Genes and Proteins in Endometrial Cancer. PMID:32899298
The Proteomics Study of Compounded HFE/TF/TfR2/HJV Genetic Variations in a Thai Family with Iron Overload, Chronic Anemia, and Motor Neuron Disorder. PMID:32895881
PCOSKBR2: a database of genes, diseases, pathways, and networks associated with polycystic ovary syndrome. PMID:32895427
Oncogenes overexpressed in metastatic oral cancers from patients with pain: potential pain mediators released in exosomes. PMID:32895418
Cytokines mapping for tissue-specific expression, eQTLs and GWAS traits. PMID:32895400
[MiR-204 inhibits invasion and metastasis of breast cancer cells by targeted regulation of HNRNPA2B1]. PMID:32895200
Identification of a metabolism-related gene expression prognostic model in endometrial carcinoma patients. PMID:32894095
MAPK cascade gene family in Camellia sinensis: In-silico identification, expression profiles and regulatory network analysis. PMID:32894062
Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures. PMID:32888495
A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes. PMID:32888406
5-Fluorouracil Conversion Pathway Mutations in Gastric Cancer. PMID:32887417
Proteomic Characterization of the Olfactory Molecular Imbalance in Dementia with Lewy Bodies. PMID:32887355
New label-free methods for protein relative quantification applied to the investigation of an animal model of Huntington Disease. PMID:32886703
Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration. PMID:32885253
Deciphering the secretome of leukocyte-platelet rich fibrin: towards a better understanding of its wound healing properties. PMID:32884030
Tumor-intrinsic and -extrinsic determinants of response to blinatumomab in adults with B-ALL. PMID:32881995
Acromelic dysplasias: how rare musculoskeletal disorders reveal biological functions of extracellular matrix proteins. PMID:32880985
Pooled analysis of radiation hybrids identifies loci for growth and drug action in mammalian cells. PMID:32878976
Secretome Proteomic Approaches for Biomarker Discovery: An Update on Colorectal Cancer. PMID:32878319
Changes in MicroRNA Expression during Rabbit Hemorrhagic Disease Virus (RHDV) Infection. PMID:32878241
Molecular Changes in Tissue Proteome during Prostate Cancer Development: Proof-of-Principle Investigation. PMID:32878211
Neuropeptides Modulate Local Astrocytes to Regulate Adult Hippocampal Neural Stem Cells. PMID:32877641
Dissecting Transcription Factor-Target Interaction in Bovine Coronavirus Infection. PMID:32872640
Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis. PMID:32872482
DoRWA3 from Dendrobium officinale Plays an Essential Role in Acetylation of Polysaccharides. PMID:32872385
Lymphocyte infiltration and key differentially expressed genes in the ulcerative colitis. PMID:32871953
CaNDis: a web server for investigation of causal relationships between diseases, drugs and drug targets. PMID:32871004
Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection. PMID:32869025
Genome-wide identification and analysis of GRAS transcription factors in the bottle gourd genome. PMID:32868844
Detection of epistasis between ACTN3 and SNAP-25 with an insight towards gymnastic aptitude identification. PMID:32866209
A Prognostic Gene-Expression Signature and Risk Score for Meningioma Recurrence After Resection. PMID:32860417
Whole-transcriptome Analysis of Fully Viable Energy Efficient Glycolytic-null Cancer Cells Established by Double Genetic Knockout of Lactate Dehydrogenase A/B or Glucose-6-Phosphate Isomerase. PMID:32859627
Comparative Transcriptome Analysis of Pine Trees Treated with Resistance-Inducing Substances against the Nematode Bursaphelenchus xylophilus. PMID:32858932
Explorative Combined Lipid and Transcriptomic Profiling of Substantia Nigra and Putamen in Parkinson's Disease. PMID:32858884
Intracellular Cryptococcus neoformans disrupts the transcriptome profile of M1- and M2-polarized host macrophages. PMID:32857777
Clinically relevant radioresistant rhabdomyosarcoma cell lines: functional, molecular and immune-related characterization. PMID:32854690
Analysis of the brain transcriptome in lines of laying hens divergently selected for feather pecking. PMID:32854615
Development of Multiscale Transcriptional Regulatory Network in Esophageal Cancer Based on Integrated Analysis. PMID:32851080
Proteomic Analysis Reveals a Mitochondrial Remodeling of βTC3 Cells in Response to Nanotopography. PMID:32850772
Identification of Novel Targets of Knee Osteoarthritis Shared by Cartilage and Synovial Tissue. PMID:32842604
Identification of biomarkers associated with synovitis in rheumatoid arthritis by bioinformatics analyses. PMID:32840301
Network Pharmacology to Identify the Pharmacological Mechanisms of a Traditional Chinese Medicine Derived from Trachelospermum jasminoides in Patients with Rheumatoid Arthritis. PMID:32840241
KG-COVID-19: a framework to produce customized knowledge graphs for COVID-19 response. PMID:32839776
Multiomics data integration unveils core transcriptional regulatory networks governing cell-type identity. PMID:32839455
How to Become an Apomixis Model: The Multifaceted Case of Paspalum. PMID:32839398
RNA-protein interaction mapping via MS2- or Cas13-based APEX targeting. PMID:32839320
Potential compound from herbal food of Rhizoma Polygonati for treatment of COVID-19 analyzed by network pharmacology: Viral and cancer signaling mechanisms. PMID:32837538
Brain Transcriptomics of Wild and Domestic Rabbits Suggests That Changes in Dopamine Signaling and Ciliary Function Contributed to Evolution of Tameness. PMID:32835359
Study of Osteoarthritis-Related Hub Genes Based on Bioinformatics Analysis. PMID:32832544
Computational-based insights into the phylogeny, structure, and function of Rhodococcus alkane-1-monooxygenase. PMID:32832341
Identification and verification of the prognostic value of the glutathione S-transferase Mu genes in gastric cancer. PMID:32831919
Inhibition of glucose assimilation in Auxenochlorella protothecoides by light. PMID:32831906
TRAF3IP2 (TRAF3 Interacting Protein 2) Mediates Obesity-Associated Vascular Insulin Resistance and Dysfunction in Male Mice. PMID:32829657
Gene Expression and RNA Splicing Imputation Identifies Novel Candidate Genes Associated with Osteoporosis. PMID:32827035
Inhibition of miRNA-34a Promotes M2 Macrophage Polarization and Improves LPS-Induced Lung Injury by Targeting Klf4. PMID:32825525
Characterization of microRNAs during Embryonic Skeletal Muscle Development in the Shan Ma Duck. PMID:32823859
A Human IgSF Cell-Surface Interactome Reveals a Complex Network of Protein-Protein Interactions. PMID:32822567
Construction and Comprehensive Analysis of a ceRNA Network to Reveal Potential Novel Biomarkers for Triple-Negative Breast Cancer. PMID:32821169
Thickness of the cerebral cortex shows positive association with blood levels of triacylglycerols carrying 18-carbon fatty acids. PMID:32820227
Genome-wide analyses reveal drivers of penguin diversification. PMID:32817535
Comprehensive genome based analysis of Vibrio parahaemolyticus for identifying novel drug and vaccine molecules: Subtractive proteomics and vaccinomics approach. PMID:32813697
Phosphorylated tau interactome in the human Alzheimer's disease brain. PMID:32812023
A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. PMID:32809827
MiR-302b as a Combinatorial Therapeutic Approach to Improve Cisplatin Chemotherapy Efficacy in Human Triple-Negative Breast Cancer. PMID:32806777
Unravelling host-pathogen interactions: ceRNA network in SARS-CoV-2 infection (COVID-19). PMID:32805314
Comprehensive Bioinformatics Analysis Reveals Hub Genes and Inflammation State of Rheumatoid Arthritis. PMID:32802866
Integrated Bioinformatics Analysis Reveals Function and Regulatory Network of miR-200b-3p in Endometriosis. PMID:32802844
Genomic Analysis of the SUMO-Conjugating Enzyme and Genes under Abiotic Stress in Potato (Solanum tuberosum L.). PMID:32802829
Gastric Cancer Heterogeneity and Clinical Outcomes. PMID:32799763
Deletion of DJ-1 in rats affects protein abundance and mitochondrial function at the synapse. PMID:32792613
Transcriptomic determinants of the response of ST-111 Pseudomonas aeruginosa AG1 to ciprofloxacin identified by a top-down systems biology approach. PMID:32792590
Altered serum protein levels in frontotemporal dementia and amyotrophic lateral sclerosis indicate calcium and immunity dysregulation. PMID:32792518
Screening and identification of key regulatory connections and immune cell infiltration characteristics for lung transplant rejection using mucosal biopsies. PMID:32791489
SARS-CoV-2 causes a specific dysfunction of the kidney proximal tubule. PMID:32791255
Combining Gene-Disease Associations with Single-Cell Gene Expression Data Provides Anatomy-Specific Subnetworks in Age-Related Macular Degeneration. PMID:32789304
Pathway-specific model estimation for improved pathway annotation by network crosstalk. PMID:32788619
Construct a circRNA/miRNA/mRNA regulatory network to explore potential pathogenesis and therapy options of clear cell renal cell carcinoma. PMID:32788609
A proteogenomic profile of early lung adenocarcinomas by protein co-expression network and genomic alteration analysis. PMID:32788598
Enterobacterial Common Antigen: Synthesis and Function of an Enigmatic Molecule. PMID:32788387
Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane. PMID:32788342
Game theoretic centrality: a novel approach to prioritize disease candidate genes by combining biological networks with the Shapley value. PMID:32787845
Combining Neurobehavioral Analysis and In Vivo Photoaffinity Labeling to Understand Protein Targets of Methamphetamine in Casper Zebrafish. PMID:32786314
Loss of Osteopontin Expression Reduces HSV-1-Induced Corneal Opacity. PMID:32785676
Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL. PMID:32785655
Collagen 24 α1 Is Increased in Insulin-Resistant Skeletal Muscle and Adipose Tissue. PMID:32785142
Quantitative Proteomics Comparison of Total Expressed Proteomes of Anisakis simplex Sensu Stricto, A. pegreffii, and Their Hybrid Genotype. PMID:32785065
Pan-Cancer Analysis of Alternative Lengthening of Telomere Activity. PMID:32784588
Identification of a five-gene signature for predicting the progression and prognosis of stage I endometrial carcinoma. PMID:32782557
Predictive and prognostic value of EPIC1 in patients with breast cancer receiving neoadjuvant chemotherapy. PMID:32782487
Cystic Fibrosis Defective Response to Infection Involves Autophagy and Lipid Metabolism. PMID:32781626
Dissecting diagnostic heterogeneity in depression by integrating neuroimaging and genetics. PMID:32781460
Identification of C3 as a therapeutic target for diabetic nephropathy by bioinformatics analysis. PMID:32778679
Identification of key genes in atrial fibrillation using bioinformatics analysis. PMID:32778054
Functional Molecular Network Analysis Enables Prediction of Response to Vedolizumab Therapy in Anti-TNF Refractory IBD Patients. PMID:32776006
Tandem mass tagged dataset used to characterize muscle-specific proteome changes in beef during early postmortem period. PMID:32775575
Integrated Bioinformatic Analysis Identifies Networks and Promising Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma. PMID:32775402
Identification of key differentially expressed genes between ER-positive/HER2-negative breast cancer and ER-negative/HER2-negative breast cancer using integrated bioinformatics analysis. PMID:32775256
miR-638 acts as an oncogene and predicts poor prognosis in renal cell carcinoma. PMID:32774724
Update analysis on the association between Methionine synthase rs1805087 A/G variant and risk of prostate cancer. PMID:32770085
Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma. PMID:32767816
Machine learning: A powerful tool for gene function prediction in plants. PMID:32765975
Identification of the association between HMMR expression and progression of hepatocellular carcinoma via construction of a co-expression network. PMID:32765791
Exploring protective effect of Glycine tabacina aqueous extract against nephrotic syndrome by network pharmacology and experimental verification. PMID:32765640
Increased expression of secreted frizzled related protein 1 (SFRP1) predicts ampullary adenocarcinoma recurrence. PMID:32764696
Genome-wide identification and characterization of DCL, AGO and RDR gene families in Saccharum spontaneum. PMID:32764599
A biochemical network modeling of a whole-cell. PMID:32764598
Cancer Cell Acid Adaptation Gene Expression Response Is Correlated to Tumor-Specific Tissue Expression Profiles and Patient Survival. PMID:32764426
Profound Reprogramming towards Stemness in Pancreatic Cancer Cells as Adaptation to AKT Inhibition. PMID:32764385
Distinct miRNA Profile of Cellular and Extracellular Vesicles Released from Chicken Tracheal Cells Following Avian Influenza Virus Infection. PMID:32764349
Global Analysis of Cereal microProteins Suggests Diverse Roles in Crop Development and Environmental Adaptation. PMID:32763954
The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation. PMID:32762776
Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach. PMID:32760426
Rescue of oxytocin response and social behaviour in a mouse model of autism. PMID:32760004
Cyclin-Dependent Kinase 1 (CDK1) is Co-Expressed with CDCA5: Their Functions in Gastric Cancer Cell Line MGC-803. PMID:32759885
Comprehensive Analysis of Expression, Clinicopathological Association and Potential Prognostic Significance of RABs in Pancreatic Cancer. PMID:32759795
Comparative gene expression profiling between optic nerve and spinal cord injury in Xenopus laevis reveals a core set of genes inherent in successful regeneration of vertebrate central nervous system axons. PMID:32758133
Integrated Analysis of Hub Genes and Pathways In Esophageal Carcinoma Based on NCBI's Gene Expression Omnibus (GEO) Database: A Bioinformatics Analysis. PMID:32756534
Bioinformatics analysis of microRNA profiles and identification of microRNA-mRNA network and biological markers in intracranial aneurysm. PMID:32756097
Integrative transcriptomics reveals genotypic impact on sugar beet storability. PMID:32754876
Potential mechanism prediction of Cold-Damp Plague Formula against COVID-19 via network pharmacology analysis and molecular docking. PMID:32754224
Identification of Gene Modules and Hub Genes Involved in Mastitis Development Using a Systems Biology Approach. PMID:32754201
Interplay Between V-ATPase G1 and Small EV-miRNAs Modulates ERK1/2 Activation in GBM Stem Cells and Nonneoplastic Milieu. PMID:32753475
PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis. PMID:32753387
Unravelling the Role of miR-20b-5p, CCNB1, HMGA2 and E2F7 in Development and Progression of Non-Small Cell Lung Cancer (NSCLC). PMID:32752229
Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade-specific epigenome and transcriptome landscapes. PMID:32747824
Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy. PMID:32747793
A deep learning framework for high-throughput mechanism-driven phenotype compound screening. PMID:32743586
Proteome dynamics analysis identifies functional roles of SDE2 and hypoxia in DNA damage response in prostate cancer cells. PMID:32743553
Identification of a Glucose Metabolism-related Signature for prediction of Clinical Prognosis in Clear Cell Renal Cell Carcinoma. PMID:32742447
Identification of the key genes and characterizations of Tumor Immune Microenvironment in Lung Adenocarcinoma (LUAD) and Lung Squamous Cell Carcinoma (LUSC). PMID:32742444
The prognostic value of COL3A1/FBN1/COL5A2/SPARC-mir-29a-3p-H19 associated ceRNA network in Gastric Cancer through bioinformatic exploration. PMID:32742441
SARS-CoV-2 Infection of Ocular Cells from Human Adult Donor Eyes and hESC-Derived Eye Organoids. PMID:32742243
ACE2 Co-evolutionary Pattern Suggests Targets for Pharmaceutical Intervention in the COVID-19 Pandemic. PMID:32738617
Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality. PMID:32737166
Unraveling the molecular pathobiology of vocal fold systemic dehydration using an in vivo rabbit model. PMID:32735560
STRING data mining of GWAS data in canine hereditary pigment-associated deafness. PMID:32734119
Integrative Bioinformatics Approaches to Screen Potential Prognostic Immune-Related Genes and Drugs in the Cervical Cancer Microenvironment. PMID:32733542
In-cell architecture of an actively transcribing-translating expressome. PMID:32732422
Changes in Proteome of Fibroblasts Isolated from Psoriatic Skin Lesions. PMID:32731552
The changing mouse embryo transcriptome at whole tissue and single-cell resolution. PMID:32728245
Production of Paralytic Shellfish Toxins (PSTs) in Toxic Alexandrium catenella is Intertwined with Photosynthesis and Energy Production. PMID:32727048
PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells. PMID:32726622
An Enteric Pathogen Subverts Colonization Resistance by Evading Competition for Amino Acids in the Gut. PMID:32726577
OmicsON - Integration of omics data with molecular networks and statistical procedures. PMID:32726348
Salivary and Serum Inflammatory Profiles Reflect Different Aspects of Inflammatory Bowel Disease Activity. PMID:32725166
A Critical Review of Proteomic Studies in Gestational Diabetes Mellitus. PMID:32724825
Identification of hub genes involved in the occurrence and development of hepatocellular carcinoma via bioinformatics analysis. PMID:32724412
Integrated Analyses of lncRNA and mRNA Profiles Reveal Characteristic and Functional Changes of Leukocytes in Qi-Deficiency Constitution and Pi-Qi-Deficiency Syndrome of Chronic Superficial Gastritis. PMID:32724329
Ubiquitin-proteasome system, lipid metabolism and DNA damage repair are triggered by antipsychotic medication in human oligodendrocytes: implications in schizophrenia. PMID:32724114
Implications of Insulin-Like Growth Factor-1 in Skeletal Muscle and Various Diseases. PMID:32722232
Batch-Learning Self-Organizing Map Identifies Horizontal Gene Transfer Candidates and Their Origins in Entire Genomes. PMID:32719664
Significant correlation between plasma proteome profile and pain intensity, sensitivity, and psychological distress in women with fibromyalgia. PMID:32719459
(Phospho)proteomic Profiling of Microsatellite Unstable CRC Cells Reveals Alterations in Nuclear Signaling and Cholesterol Metabolism Caused by Frameshift Mutation of NMD Regulator UPF3A. PMID:32718059
Network Approaches for Dissecting the Immune System. PMID:32717640
Construction of a novel prognostic-predicting model correlated to ovarian cancer. PMID:32716025
OASL as a Diagnostic Marker for Influenza Infection Revealed by Integrative Bioinformatics Analysis With XGBoost. PMID:32714913
A Pharmacological Interactome between COVID-19 Patient Samples and Human Sensory Neurons Reveals Potential Drivers of Neurogenic Pulmonary Dysfunction. PMID:32714114
PhosphoEffect: Prioritizing Variants On or Adjacent to Phosphorylation Sites through Their Effect on Kinase Recognition Motifs. PMID:32712465
Revealing the Proteome of Motor Cortex Derived Extracellular Vesicles Isolated from Amyotrophic Lateral Sclerosis Human Postmortem Tissues. PMID:32708779
Inflammatory Breast Carcinoma: Elevated microRNA miR-181b-5p and Reduced miR-200b-3p, miR-200c-3p, and miR-203a-3p Expression as Potential Biomarkers with Diagnostic Value. PMID:32708601
Comparative proteomic analysis uncovers potential biomarkers involved in the anticancer effect of Scutellarein in human gastric cancer cells. PMID:32705238
Downregulation of miR‑193a‑3p via targeting cyclin D1 in thyroid cancer. PMID:32705210
Intrinsic transcriptomic sex differences in human endothelial cells at birth and in adults are associated with coronary artery disease targets. PMID:32704153
IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma. PMID:32704112
Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice. PMID:32703241
Proteinarium: Multi-sample protein-protein interaction analysis and visualization tool. PMID:32702417
Eukaryote-Conserved Methylarginine Is Absent in Diplomonads and Functionally Compensated in Giardia. PMID:32702104
Identifying the novel key genes in renal cell carcinoma by bioinformatics analysis and cell experiments. PMID:32699530
BH4 activates CaMKK2 and rescues the cardiomyopathic phenotype in rodent models of diabetes. PMID:32699151
Parallel bimodal single-cell sequencing of transcriptome and chromatin accessibility. PMID:32699019
Pseudo-RNA-Binding Domains Mediate RNA Structure Specificity in Upstream of N-Ras. PMID:32697992
Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins. PMID:32697195
Gene regulation network analysis reveals core genes associated with survival in glioblastoma multiforme. PMID:32696617
Gut transcriptomic changes during hibernation in the greater horseshoe bat (Rhinolophus ferrumequinum). PMID:32690984
A new survival model based on ferroptosis-related genes for prognostic prediction in clear cell renal cell carcinoma. PMID:32688345
Prognostic and Predictive Value of Cadherin 11 for Patients with Gastric Cancer and Its Correlation with Tumor Microenvironment: Results from Microarray Analysis. PMID:32685527
Identification of COVID-19 Infection-Related Human Genes Based on a Random Walk Model in a Virus-Human Protein Interaction Network. PMID:32685484
Comparative Transcriptome Analysis Reveals the Potential Cardiovascular Protective Targets of the Thyroid Hormone Metabolite 3-Iodothyronamine (3-T1AM). PMID:32685439
Identification of potential crucial genes in atrial fibrillation: a bioinformatic analysis. PMID:32682418
Heme Uptake in Lactobacillus sakei Evidenced by a New Energy Coupling Factor (ECF)-Like Transport System. PMID:32680867
Potential Involvement of lncRNAs in the Modulation of the Transcriptome Response to Nodavirus Challenge in European Sea Bass (Dicentrarchus labrax L.). PMID:32679770
Matrix metallopeptidase 9 as a host protein target of chloroquine and melatonin for immunoregulation in COVID-19: A network-based meta-analysis. PMID:32679150
Transcriptome analysis of the zebrafish atoh7-/- Mutant, lakritz, highlights Atoh7-dependent genetic networks with potential implications for human eye diseases. PMID:32676583
Development and validation of an integrative methylation signature and nomogram for predicting survival in clear cell renal cell carcinoma. PMID:32676392
Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources. PMID:32676006
Transcriptional Profiling of Normal, Stenotic, and Regurgitant Human Aortic Valves. PMID:32674273
Dataset of bovine mammary gland dry secretion proteome from the end of lactation through day 21 of the dry period. PMID:32671157
Back-Splicing Transcript Isoforms (Circular RNAs) Affect Biologically Relevant Pathways and Offer an Additional Layer of Information to Stratify NMIBC Patients. PMID:32670866
Merging microarray studies to identify a common gene expression signature to several structural heart diseases. PMID:32670412
Systematic Identification of lncRNA-Associated ceRNA Networks in Immune Thrombocytopenia. PMID:32670393
Identification of Hub Genes in Protective Effect of Astragaloside IV on Aconitine-Induced Cardiac Damage in Zebrafish Based on Bioinformatics Analysis. PMID:32670070
Ageing hallmarks exhibit organ-specific temporal signatures. PMID:32669715
Bioinformatics analysis of potential core genes for glioblastoma. PMID:32667033
Association of genetic variants at CETP, AGER, and CYP4F2 locus with the risk of atrophic age-related macular degeneration. PMID:32666702
Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks. PMID:32665557
Prothrombin is a binding partner of the human receptor of advanced glycation end products. PMID:32665403
eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition. PMID:32665273
Identification of potential crucial genes and key pathways in osteosarcoma. PMID:32665038
SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis. PMID:32664949
Identification of Target Genes in Hypertension and Left Ventricular Remodeling. PMID:32664164
Integrative pharmacological mechanism of vitamin C combined with glycyrrhizic acid against COVID-19: findings of bioinformatics analyses. PMID:32662814
Sex- and Region-Specific Differences in the Transcriptomes of Rat Microglia from the Brainstem and Cervical Spinal Cord. PMID:32661056
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding. PMID:32658293
Prediction of cancer driver genes through network-based moment propagation of mutation scores. PMID:32657361
Microenvironment-related gene TNFSF13B predicts poor prognosis in kidney renal clear cell carcinoma. PMID:32655996
Integrative analysis of competitive endogenous RNA network reveals the regulatory role of non-coding RNAs in high-glucose-induced human retinal endothelial cells. PMID:32655995
Non-photoreceptor Expression of Tulp1 May Contribute to Extensive Retinal Degeneration in Tulp1-/- Mice. PMID:32655363
Overrepresentation of genetic variation in the AnkyrinG interactome is related to a range of neurodevelopmental disorders. PMID:32651551
A bioinformatics investigation into molecular mechanism of Yinzhihuang granules for treating hepatitis B by network pharmacology and molecular docking verification. PMID:32651427
Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19. PMID:32651212
A literature-based approach for curating gene signatures in multifaceted diseases. PMID:32650786
Distinct Microbiota Dysbiosis in Patients with Non-Erosive Reflux Disease and Esophageal Adenocarcinoma. PMID:32650561
The Lyme disease bacterium, Borrelia burgdorferi, stimulates an inflammatory response in human choroid plexus epithelial cells. PMID:32645014
20(S)-Protopanaxatriol promotes the binding of P53 and DNA to regulate the antitumor network via multiomic analysis. PMID:32642409
Novel Proteome Extraction Method Illustrates a Conserved Immunological Signature of MSI-H Colorectal Tumors. PMID:32641473
Protein-Protein Interactions Efficiently Modeled by Residue Cluster Classes. PMID:32640745
ProVision: a web-based platform for rapid analysis of proteomics data processed by MaxQuant. PMID:32638008
metPropagate: network-guided propagation of metabolomic information for prioritization of metabolic disease genes. PMID:32637154
Genome-Scale Metabolic Model Driven Design of a Defined Medium for Campylobacter jejuni M1cam. PMID:32636809
Extending TextAE for annotation of non-contiguous entities. PMID:32634869
Expression of Annexin A2 Promotes Cancer Progression in Estrogen Receptor Negative Breast Cancers. PMID:32629869
Systems biology comprehensive analysis on breast cancer for identification of key gene modules and genes associated with TNM-based clinical stages. PMID:32616754
Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short- and long-term models. PMID:32615317
Seq-ing answers: Current data integration approaches to uncover mechanisms of transcriptional regulation. PMID:32612756
ERK Regulates NeuroD1-mediated Neurite Outgrowth via Proteasomal Degradation. PMID:32606250
Glioma escape signature and clonal development under immune pressure. PMID:32603315
Mass Spectrometry Based-Proteomic Analysis of Anisakis spp.: A Preliminary Study towards a New Diagnostic Tool. PMID:32599802
Genetic Basis of Maize Resistance to Multiple Insect Pests: Integrated Genome-Wide Comparative Mapping and Candidate Gene Prioritization. PMID:32599710
Potential Molecular Mechanisms and Drugs for Aconitine-Induced Cardiotoxicity in Zebrafish through RNA Sequencing and Bioinformatics Analysis. PMID:32598336
The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB. PMID:32597296
Novel Insights Into Triple-Negative Breast Cancer Prognosis by Comprehensive Characterization of Aberrant Alternative Splicing. PMID:32595697
Identifying persistent structures in multiscale 'omics data. PMID:32587977
Recurrent Amplification of the Osmotic Stress Transcription Factor NFAT5 in Adrenocortical Carcinoma. PMID:32587934
A systems genetics approach to revealing the Pdgfb molecular network of the retina. PMID:32587457
Impact of a natural disaster on access to care and biopsychosocial outcomes among Hispanic/Latino cancer survivors. PMID:32587352
MiR-200b in heme oxygenase-1-modified bone marrow mesenchymal stem cell-derived exosomes alleviates inflammatory injury of intestinal epithelial cells by targeting high mobility group box 3. PMID:32587254
Alterations in the chondrocyte surfaceome in response to pro-inflammatory cytokines. PMID:32586320
Generation of High Yielding and Fragrant Rice (Oryza sativa L.) Lines by CRISPR/Cas9 Targeted Mutagenesis of Three Homoeologs of Cytochrome P450 Gene Family and OsBADH2 and Transcriptome and Proteome Profiling of Revealed Changes Triggered by Mutations. PMID:32586052
Systemic Alterations of Immune Response-Related Proteins during Glaucoma Development in the Murine Model DBA/2J. PMID:32585848
Neutrophils, Crucial, or Harmful Immune Cells Involved in Coronavirus Infection: A Bioinformatics Study. PMID:32582303
Absence of miRNA-146a Differentially Alters Microglia Function and Proteome. PMID:32582192
Identification of Post-myocardial Infarction Blood Expression Signatures Using Multiple Feature Selection Strategies. PMID:32581823
Distinct abdominal and gluteal adipose tissue transcriptome signatures are altered by exercise training in African women with obesity. PMID:32581226
Identification of Target Genes and Transcription Factors in Mice with LMNA-Related Dilated Cardiomyopathy by Integrated Bioinformatic Analyses. PMID:32581210
Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis. PMID:32580699
Learning Representations to Predict Intermolecular Interactions on Large-Scale Heterogeneous Molecular Association Network. PMID:32580123
Time-series proteomic study of the response of HK-2 cells to hyperglycemic, hypoxic diabetic-like milieu. PMID:32579601
An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1. PMID:32579471
Composition of Caenorhabditis elegans extracellular vesicles suggests roles in metabolism, immunity, and aging. PMID:32578074
TGFβ activity released from platelet-rich fibrin adsorbs to titanium surface and collagen membranes. PMID:32576959
Bioinformatics Approach for Identifying Novel Biomarkers and Their Signaling Pathways Involved in Interstitial Cystitis/Bladder Pain Syndrome with Hunner Lesion. PMID:32575815
Uncovering Potential Roles of Differentially Expressed Genes, Upstream Regulators, and Canonical Pathways in Endometriosis Using an In Silico Genomics Approach. PMID:32575462
Genome-wide transcriptome architecture in a mouse model of Gulf War Illness. PMID:32574576
Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria. PMID:32571917
PSPC1 Potentiates IGF1R Expression to Augment Cell Adhesion and Motility. PMID:32570949
Host transcriptome-guided drug repurposing for COVID-19 treatment: a meta-analysis based approach. PMID:32566414
Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection. PMID:32566226
Identification of key genes associated with the progression of intrahepatic cholangiocarcinoma using weighted gene co-expression network analysis. PMID:32565973
Prognostic and predictive value of immune/stromal-related gene biomarkers in renal cell carcinoma. PMID:32565957
Identification of Active Compounds of Mahuang Fuzi Xixin Decoction and Their Mechanisms of Action by LC-MS/MS and Network Pharmacology. PMID:32565854
Ectopic Expression of a Self-Incompatibility Module Triggers Growth Arrest and Cell Death in Vegetative Cells. PMID:32561539
Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan-McDermid syndrome and autism. PMID:32560742
Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation. PMID:32560730
Germline Mutation Enrichment in Pathways Controlling Endothelial Cell Homeostasis in Patients with Brain Arteriovenous Malformation: Implication for Molecular Diagnosis. PMID:32560555
Role of Anillin in Tumour: From a Prognostic Biomarker to a Novel Target. PMID:32560530
Ab initio GO-based mining for non-tandem-duplicated functional clusters in three model plant diploid genomes. PMID:32559249
PasT of Escherichia coli sustains antibiotic tolerance and aerobic respiration as a bacterial homolog of mitochondrial Coq10. PMID:32558363
Microarray analysis of the expression profile of immune-related gene in rapid recurrence early-stage lung adenocarcinoma. PMID:32556504
Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche. PMID:32556172
Identification of eQTLs associated with lipid metabolism in Longissimus dorsi muscle of pigs with different genetic backgrounds. PMID:32555447
Using the TCGA Database to Predict and Analyze Tumor Microenvironment Genes Related to Poor Prognosis of Colon Cancer. PMID:32555128
An Interaction Network of RNA-Binding Proteins Involved in Drosophila Oogenesis. PMID:32554711
The stem cell marker Prom1 promotes axon regeneration by down-regulating cholesterol synthesis via Smad signaling. PMID:32554499
Genomic Rewiring of SOX2 Chromatin Interaction Network during Differentiation of ESCs to Postmitotic Neurons. PMID:32553182
Cold priming uncouples light- and cold-regulation of gene expression in Arabidopsis thaliana. PMID:32552683
An age-independent gene signature for monitoring acute rejection in kidney transplantation. PMID:32550916
Network Pharmacology and Experimental Evidence Reveal Dioscin Suppresses Proliferation, Invasion, and EMT via AKT/GSK3b/mTOR Signaling in Lung Adenocarcinoma. PMID:32546976
Structure, Function, and Regulation of the SRMS Tyrosine Kinase. PMID:32545875
RNA Binding Proteins as Drivers and Therapeutic Target Candidates in Pancreatic Ductal Adenocarcinoma. PMID:32545414
Mass Spectrometric Comparison of HPV-Positive and HPV-Negative Oropharyngeal Cancer. PMID:32545200
Abasy Atlas v2.2: The most comprehensive and up-to-date inventory of meta-curated, historical, bacterial regulatory networks, their completeness and system-level characterization. PMID:32542109
A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors. PMID:32540914
Genome-wide analysis of proline-rich extension-like receptor protein kinase (PERK) in Brassica rapa and its association with the pollen development. PMID:32539701
TEAD-YAP Interaction Inhibitors and MDM2 Binders from DNA-Encoded Indole-Focused Ugi Peptidomimetics. PMID:32537835
Integrated Analyses Identify Immune-Related Signature Associated with Qingyihuaji Formula for Treatment of Pancreatic Ductal Adenocarcinoma Using Network Pharmacology and Weighted Gene Co-Expression Network. PMID:32537471
Bioentity2vec: Attribute- and behavior-driven representation for predicting multi-type relationships between bioentities. PMID:32533701
Induction of the Endoplasmic-Reticulum-Stress Response: MicroRNA-34a Targeting of the IRE1α-Branch. PMID:32531952
Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia. PMID:32531060
Identification of Hub Genes Associated With Development of Head and Neck Squamous Cell Carcinoma by Integrated Bioinformatics Analysis. PMID:32528874
The Mutant p53-Driven Secretome Has Oncogenic Functions in Pancreatic Ductal Adenocarcinoma Cells. PMID:32526853
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation. PMID:32513696
The landscape of host genetic factors involved in immune response to common viral infections. PMID:32511533
Overexpressed gene signature of EPH receptor A/B family in cancer patients-comprehensive analyses from the public high-throughput database. PMID:32509099
Construction and Validation of a 13-Gene Signature for Prognosis Prediction in Medulloblastoma. PMID:32508873
PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy. PMID:32508664
Comprehensive genomic profiling of urothelial carcinoma cell lines reveals hidden research bias and caveats. PMID:32508016
Analysis of the molecular mechanism of Pudilan (PDL) treatment for COVID-19 by network pharmacology tools. PMID:32505821
Comparative Target Analysis of Chlorinated Biphenyl Antimicrobials Highlights MenG as a Molecular Target of Triclocarban. PMID:32503913
Transcriptome and Network Analyses of Heterostyly in Turnera subulata Provide Mechanistic Insights: Are S-Loci a Red-Light for Pistil Elongation? PMID:32503265
Zebrafish rbm8a and magoh mutants reveal EJC developmental functions and new 3'UTR intron-containing NMD targets. PMID:32502192
Can network pharmacology identify the anti-virus and anti- inflammatory activities of Shuanghuanglian oral liquid used in Chinese medicine for respiratory tract infection? PMID:32501408
CRISPR screen in regulatory T cells reveals modulators of Foxp3. PMID:32499641
Extracellular Vesicles Enriched in hsa-miR-301a-3p and hsa-miR-1293 Dynamics in Clear Cell Renal Cell Carcinoma Patients: Potential Biomarkers of Metastatic Disease. PMID:32498409
A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction. PMID:32497778
Identification of prognostic gene biomarkers for metastatic skin cancer using data mining. PMID:32494360
AMPK Profiling in Rodent and Human Pancreatic Beta-Cells under Nutrient-Rich Metabolic Stress. PMID:32492936
Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification. PMID:32492250
Guizhi Fuling Decoction inhibiting the PI3K and MAPK pathways in breast cancer cells revealed by HTS2 technology and systems pharmacology. PMID:32489526
DNA methylation profiling to predict overall survival risk in gastric cancer: development and validation of a nomogram to optimize clinical management. PMID:32489454
Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition. PMID:32488085
Identification and characterization of male reproduction-related genes in pig (Sus scrofa) using transcriptome analysis. PMID:32487021
Cadmium, Smoking, and Human Blood DNA Methylation Profiles in Adults from the Strong Heart Study. PMID:32484362
Selective Mediator dependence of cell-type-specifying transcription. PMID:32483291
Implications of Skeletal Muscle Extracellular Matrix Remodeling in Metabolic Disorders: Diabetes Perspective. PMID:32481704
In silico analysis of the molecular regulatory networks in peripheral arterial occlusive disease. PMID:32481342
Protein Network Studies on PCOS Biomarkers With S100A8, Druggability Assessment, and RNA Aptamer Designing to Control Its Cyst Migration Effect. PMID:32478041
Resveratrol: Multi-Targets Mechanism on Neurodegenerative Diseases Based on Network Pharmacology. PMID:32477148
Anti-Alzheimer's Disease Molecular Mechanism of Acori Tatarinowii Rhizoma Based on Network Pharmacology. PMID:32475979
A Bayesian data fusion based approach for learning genome-wide transcriptional regulatory networks. PMID:32471360
Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer. PMID:32471192
Prevention of age-associated neuronal hyperexcitability with improved learning and attention upon knockout or antagonism of LPAR2. PMID:32468095
High-resolution annotation of the mouse preimplantation embryo transcriptome using long-read sequencing. PMID:32461551
Degradation of MicroRNA miR-466d-3p by Japanese Encephalitis Virus NS3 Facilitates Viral Replication and Interleukin-1β Expression. PMID:32461319
Bioinformatics Analysis and Identification of Underlying Biomarkers Potentially Linking Allergic Rhinitis and Asthma. PMID:32460303
Epigenetic inheritance of circadian period in clonal cells. PMID:32459177
Machine learning-aided quantification of antibody-based cancer immunotherapy by natural killer cells in microfluidic droplets. PMID:32458907
Construction and Analysis of a ceRNA Network Reveals Potential Prognostic Markers in Colorectal Cancer. PMID:32457800
Unstructured Biology of Proteins from Ubiquitin-Proteasome System: Roles in Cancer and Neurodegenerative Diseases. PMID:32455657
Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus. PMID:32451473
Identification of single nucleotide pleomorphisms associated with periodontal disease in head and neck cancer irradiation patients by exome sequencing. PMID:32451231
Exome sequencing study revealed novel susceptibility loci in subarachnoid hemorrhage (SAH). PMID:32450902
The features of polyglutamine regions depend on their evolutionary stability. PMID:32448113
Cancer During Pregnancy: The Role of Vascular Toxicity in Chemotherapy-Induced Placental Toxicity. PMID:32443608
Arrayed CRISPR Screening Identifies Novel Targets That Enhance the Productive Delivery of mRNA by MC3-Based Lipid Nanoparticles. PMID:32441189
Environment-Sensing Aryl Hydrocarbon Receptor Inhibits the Chondrogenic Fate of Modulated Smooth Muscle Cells in Atherosclerotic Lesions. PMID:32441123
Bioinformatic analysis reveals the importance of epithelial-mesenchymal transition in the development of endometriosis. PMID:32439908
Effects of PUMILIO1 and PUMILIO2 knockdown on cardiomyogenic differentiation of human embryonic stem cells culture. PMID:32437472
Posttranslational modification of Elongation Factor P from Staphylococcus aureus. PMID:32436337
Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. PMID:32435206
Bioinformatics Analysis Identifies the Estrogen Receptor 1 (ESR1) Gene and hsa-miR-26a-5p as Potential Prognostic Biomarkers in Patients with Intrahepatic Cholangiocarcinoma. PMID:32435051
Gene expression of functionally-related genes coevolves across fungal species: detecting coevolution of gene expression using phylogenetic comparative methods. PMID:32434474
Dendritic cells in tumor microenvironment promoted the neuropathic pain via paracrine inflammatory and growth factors. PMID:32434423
Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways. PMID:32433643
Gene regulation could be attributed to TCF3 and other key transcription factors in the muscle of pubertal heifers. PMID:32432381
In silico Analyses of Core Proteins and Putative Effector and Immunity Proteins for T6SS in Enterohemorrhagic E. coli. PMID:32432054
Combinational approach of retrospective clinical evidence and transcriptomics highlight AMH superiority to FSH, as successful ICSI outcome predictor. PMID:32430730
Dynamic Transcriptomic and Phosphoproteomic Analysis During Cell Wall Stress in Aspergillus nidulans. PMID:32430394
Characterization of Stem-like Circulating Tumor Cells in Pancreatic Cancer. PMID:32429174
MiR-16-5p regulates postmenopausal osteoporosis by directly targeting VEGFA. PMID:32427128
Analysis of the autoimmune regulator (AIRE) gene variant rs2075876 (G/A) association with breast cancer susceptibility. PMID:32426878
Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients - A Bioinformatics Approach. PMID:32426333
Identification of Immune Cell Landscape and Construction of a Novel Diagnostic Nomogram for Crohn's Disease. PMID:32425988
Post-translational Modification Crosstalk and Hotspots in Sirtuin Interactors Implicated in Cardiovascular Diseases. PMID:32425973
Genome Comparison Identifies Different Bacillus Species in a Bast Fibre-Retting Bacterial Consortium and Provides Insights into Pectin Degrading Genes. PMID:32424209
LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2. PMID:32424143
Proteomic Characterization of Colorectal Cancer Cells versus Normal-Derived Colon Mucosa Cells: Approaching Identification of Novel Diagnostic Protein Biomarkers in Colorectal Cancer. PMID:32422974
MCM2 and NUSAP1 Are Potential Biomarkers for the Diagnosis and Prognosis of Pancreatic Cancer. PMID:32420375
A Network Pharmacology-Based Study on the Anti-Lung Cancer Effect of Dipsaci Radix. PMID:32419823
CDK4/6 inhibition presents as a therapeutic option for paediatric and adult germ cell tumours and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms. PMID:32418994
miR-622 is a novel potential biomarker of breast carcinoma and impairs motility of breast cancer cells through targeting NUAK1 kinase. PMID:32418991
Integrative Analysis of Periostin in Primary and Advanced Prostate Cancer. PMID:32416542
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19. PMID:32416070
Comprehensive transcriptomic analysis identifies novel regulators of lung adenocarcinoma. PMID:32415511
Functional Link between miR-200a and ELK3 Regulates the Metastatic Nature of Breast Cancer. PMID:32414208
Identification and validation of hub microRNAs dysregulated in esophageal squamous cell carcinoma. PMID:32412911
Whole exome sequencing in patients with Williams-Beuren syndrome followed by disease modeling in mice points to four novel pathways that may modify stenosis risk. PMID:32412588
A therapeutic perspective for proliferative vitreoretinopathy based on the inhibition of epithelial-mesenchymal transition by miR-194. PMID:32411748
Prognostic implication and functional exploration for microRNA-20a as a molecular biomarker of gastrointestinal cancer. PMID:32410584
Global Landscapes of the Na+/H+ Antiporter (NHX) Family Members Uncover their Potential Roles in Regulating the Rapeseed Resistance to Salt Stress. PMID:32408717
Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients. PMID:32407669
Identification of pathogenic TRAIL-expressing innate immune cells during HIV-1 infection in humanized mice by scRNA-Seq. PMID:32406872
Decoding the vital segments in human ATP-dependent RNA helicase. PMID:32405168
Combining Bioinformatics and Experiments to Identify CREB1 as a Key Regulator in Senescent Granulosa Cells. PMID:32403258
In silico analyses identify lncRNAs: WDFY3-AS2, BDNF-AS and AFAP1-AS1 as potential prognostic factors for patients with triple-negative breast tumors. PMID:32401758
TRANSPIRE: A Computational Pipeline to Elucidate Intracellular Protein Movements from Spatial Proteomics Data Sets. PMID:32401031
Could CTSK and COL4A2 be specific biomarkers of poor prognosis for patients with gastric cancer in Asia?-a microarray analysis based on regional population. PMID:32399279
Visualize omics data on networks with Omics Visualizer, a Cytoscape App. PMID:32399202
A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice. PMID:32398372
Heterogeneity of proteome dynamics between connective tissue phases of adult tendon. PMID:32393437
Clinical and prognostic association of oncogene cadherin 11 in gastric cancer. PMID:32391104
Transcription Factor Profiling to Predict Recurrence-Free Survival in Breast Cancer: Development and Validation of a Nomogram to Optimize Clinical Management. PMID:32391054
Iron Limitation in Klebsiella pneumoniae Defines New Roles for Lon Protease in Homeostasis and Degradation by Quantitative Proteomics. PMID:32390954
Elevated TNFRSF4 gene expression is a predictor of poor prognosis in non-M3 acute myeloid leukemia. PMID:32390761
Identification of HMG-box family establishes the significance of SOX6 in the malignant progression of glioblastoma. PMID:32388501
Identification of differentially expressed genes and biological pathways in para-carcinoma tissues of HCC with different metastatic potentials. PMID:32382332
Comprehensive analysis of the long non-coding RNA-associated competitive endogenous RNA network reveals novel prognostic biomarkers in Wilms' tumor. PMID:32382326
Bioinformatics analyses and biological function of lncRNA ZFPM2-AS1 and ZFPM2 gene in hepatocellular carcinoma. PMID:32382322
Network Pharmacology Study of Heat-Clearing and Detoxifying Traditional Chinese Medicine for Alzheimer's Disease. PMID:32382304
Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation. PMID:32382029
Primary ovarian insufficiency, meiosis and DNA repair. PMID:32381463
RNA-seq and network analysis reveal unique glial gene expression signatures during prion infection. PMID:32381108
Circulating microRNAs correlate to clinical parameters in individuals with allergic and non-allergic asthma. PMID:32381094
Asian Zika Virus Isolate Significantly Changes the Transcriptional Profile and Alternative RNA Splicing Events in a Neuroblastoma Cell Line. PMID:32380717
Aberrant expression of two miRNAs promotes proliferation, hepatitis B virus amplification, migration and invasion of hepatocellular carcinoma cells: evidence from bioinformatic analysis and experimental validation. PMID:32377460
ECMPride: prediction of human extracellular matrix proteins based on the ideal dataset using hybrid features with domain evidence. PMID:32377454
Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation. PMID:32376919
Diversification of piRNAs expressed in PGCs and somatic cells during embryonic gonadal development. PMID:32375541
Identification of Susceptibility Loci for Spontaneous Coronary Artery Dissection. PMID:32374345
Clinical and Biological Significances of a Methyltransferase-Related Signature in Diffuse Glioma. PMID:32373523
Molecular Mechanisms of Trophoblast Dysfunction Mediated by Imbalance between STOX1 Isoforms. PMID:32371375
Plasma-Derived Extracellular Vesicles Convey Protein Signatures that Reflect Pathophysiology in Lung and Pancreatic Adenocarcinomas. PMID:32370304
Epigenetic regulation of neuronal cell specification inferred with single cell "Omics" data. PMID:32368329
The miR-1224-5p/ELF3 Axis Regulates Malignant Behaviors of Pancreatic Cancer via PI3K/AKT/Notch Signaling Pathways. PMID:32368099
Limited Proteolysis of Cyclooxygenase-2 Enhances Cell Proliferation. PMID:32366045
Differentially Expressed Genes of Natural Killer Cells Can Distinguish Rheumatoid Arthritis Patients from Healthy Controls. PMID:32365786
Proteomic profiling of Serratia marcescens by high-resolution mass spectrometry. PMID:32363156
Integrative Proteome and Acetylome Analyses of Murine Responses to Cryptococcus neoformans Infection. PMID:32362878
Proteomic profiling and bioinformatics analysis identify key regulators during the process from fanconi anemia to acute myeloid leukemia. PMID:32355551
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair. PMID:32355159
Proteomic Profiling of Colon Cancer Tissues: Discovery of New Candidate Biomarkers. PMID:32353950
An Integrated Approach Exploring the Synergistic Mechanism of Herbal Pairs in a Botanical Dietary Supplement: A Case Study of a Liver Protection Health Food. PMID:32351982
Proteomic analysis and interactions network in leaves of mycorrhizal and nonmycorrhizal sorghum plants under water deficit. PMID:32351787
RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways. PMID:32350291
Identification of co-expressed genes associated with MLL rearrangement in pediatric acute lymphoblastic leukemia. PMID:32347296
Bmi1 inhibitor PTC-209 promotes Chemically-induced Direct Cardiac Reprogramming of cardiac fibroblasts into cardiomyocytes. PMID:32346096
T cell costimulation, checkpoint inhibitors and anti-tumor therapy. PMID:32345776
Uncovering the mechanism of the effects of Paeoniae Radix Alba on iron-deficiency anaemia through a network pharmacology-based strategy. PMID:32345291
Genetic Dissection of Hypertrophic Cardiomyopathy with Myocardial RNA-Seq. PMID:32344918
Breakpoint Mapping of Symptomatic Balanced Translocations Links the EPHA6, KLF13 and UBR3 Genes to Novel Disease Phenotype. PMID:32344861
Increased Protein S-Glutathionylation in Leber's Hereditary Optic Neuropathy (LHON). PMID:32344771
A Novel Combination of Vitamin C, Curcumin and Glycyrrhizic Acid Potentially Regulates Immune and Inflammatory Response Associated with Coronavirus Infections: A Perspective from System Biology Analysis. PMID:32344708
A data-driven hypothesis on the epigenetic dysregulation of host metabolism by SARS coronaviral infection: Potential implications for the SARS-CoV-2 modus operandi. PMID:32344305
Disease-associated astrocytes in Alzheimer's disease and aging. PMID:32341542
Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons. PMID:32341540
Identification of Key Genes Related to Lung Squamous Cell Carcinoma Using Bioinformatics Analysis. PMID:32340320
Drug Research Meets Network Science: Where Are We? PMID:32338900
Linc-ROR promotes the progression of breast cancer and decreases the sensitivity to rapamycin through miR-194-3p targeting MECP2. PMID:32335998
A mycorrhizae-like gene regulates stem cell and gametophore development in mosses. PMID:32332755
Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2. PMID:32332097
The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients. PMID:32331418
Effect of the Most Relevant CYP3A4 and CYP3A5 Polymorphisms on the Pharmacokinetic Parameters of 10 CYP3A Substrates. PMID:32331352
Comprehensive Analysis of the Tumor Microenvironment in Cutaneous Melanoma associated with Immune Infiltration. PMID:32328190
Prognostic Inflammasome-Related Signature Construction in Kidney Renal Clear Cell Carcinoma Based on a Pan-Cancer Landscape. PMID:32328125
Sequential Interferon β-Cisplatin Treatment Enhances the Surface Exposure of Calreticulin in Cancer Cells via an Interferon Regulatory Factor 1-Dependent Manner. PMID:32326356
Moesin (MSN) as a Novel Proteome-Based Diagnostic Marker for Early Detection of Invasive Bladder Urothelial Carcinoma in Liquid-Based Cytology. PMID:32326232
Bioinformatics Methods for Mass Spectrometry-Based Proteomics Data Analysis. PMID:32326049
Genetics and Epigenetics of Atopic Dermatitis: An Updated Systematic Review. PMID:32325630
BioConceptVec: Creating and evaluating literature-based biomedical concept embeddings on a large scale. PMID:32324731
Quantitative SWATH-Based Proteomic Profiling for Identification of Mechanism-Driven Diagnostic Biomarkers Conferring in the Progression of Metastatic Prostate Cancer. PMID:32322560
A proximity-labeling proteomic approach to investigate invadopodia molecular landscape in breast cancer cells. PMID:32321993
Assigning a role for chemosensory signal transduction in Campylobacter jejuni biofilms using a combined omics approach. PMID:32321947
The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis. PMID:32321914
Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression. PMID:32321809
Upregulated expression of SAC3D1 is associated with progression in gastric cancer. PMID:32319600
Binge Alcohol Exposure in Adolescence Impairs Normal Heart Growth. PMID:32319345
Novel Target Exploration from Hypothetical Proteins of Klebsiella pneumoniae MGH 78578 Reveals a Protein Involved in Host-Pathogen Interaction. PMID:32318354
Identification of Potential Biomarkers for Anti-PD-1 Therapy in Melanoma by Weighted Correlation Network Analysis. PMID:32316408
MYC Controls the Epstein-Barr Virus Lytic Switch. PMID:32315601
Dissecting the Structural Organization of Multiprotein Amyloid Aggregates Using a Bottom-Up Approach. PMID:32315153
Identification of potential crucial genes in monocytes for atherosclerosis using bioinformatics analysis. PMID:32314637
Molecular Aspects of Adipose-Derived Stromal Cell Senescence in a Long-Term Culture: A Potential Role of Inflammatory Pathways. PMID:32314614
Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis. PMID:32314116
Identification of Four Pathological Stage-Relevant Genes in Association with Progression and Prognosis in Clear Cell Renal Cell Carcinoma by Integrated Bioinformatics Analysis. PMID:32309427
Interpreting the Pharmacological Mechanisms of Huachansu Capsules on Hepatocellular Carcinoma Through Combining Network Pharmacology and Experimental Evaluation. PMID:32308626
Overexpression of COL24A1 in Hepatocellular Carcinoma Predicts Poor Prognosis: A Study Based on Multiple Databases, Clinical Samples and Cell Lines. PMID:32308416
Ceramide launches an acute anti-adhesion pro-migration cell signaling program in response to chemotherapy. PMID:32307766
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network-molecular docking-LC-MSE analysis. PMID:32307268
Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder. PMID:32306996
Quantitative Proteomics Reveals Docosahexaenoic Acid-Mediated Neuroprotective Effects in Lipopolysaccharide-Stimulated Microglial Cells. PMID:32302149
Identification of Pan-Cancer Prognostic Biomarkers Through Integration of Multi-Omics Data. PMID:32300588
Analysis of the Interaction Network of Hub miRNAs-Hub Genes, Being Involved in Idiopathic Pulmonary Fibers and Its Emerging Role in Non-small Cell Lung Cancer. PMID:32300359
The Hsp90 Inhibitor, Monorden, Is a Promising Lead Compound for the Development of Novel Fungicides. PMID:32300352
The Interaction Between lncRNA SNHG6 and hnRNPA1 Contributes to the Growth of Colorectal Cancer by Enhancing Aerobic Glycolysis Through the Regulation of Alternative Splicing of PKM. PMID:32296635
Circulating RNA Transcriptome of Pregnant Women with TSH Just Above the Trimester-Specific Reference and its Correlation with the Hypertensive Phenotype. PMID:32296081
Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses. PMID:32295833
Intercellular Transmission of a Synthetic Bacterial Cytotoxic Prion-Like Protein in Mammalian Cells. PMID:32291306
Construction of a Lectin-Glycan Interaction Network from Enterohemorrhagic Escherichia coli Strains by Multi-omics Analysis. PMID:32290560
Zika virus infection differentially affects genome-wide transcription in neuronal cells and myeloid dendritic cells. PMID:32287277
Minimally altering a critical kinase for low-phytate maize. PMID:32286385
mPTP Proteins Regulated by Streptozotocin-Induced Diabetes Mellitus Are Effectively Involved in the Processes of Maintaining Myocardial Metabolic Adaptation. PMID:32283821
Structured reviews for data and knowledge-driven research. PMID:32283553
TREND: a platform for exploring protein function in prokaryotes based on phylogenetic, domain architecture and gene neighborhood analyses. PMID:32282909
Bioinformatic identification of hub genes and key pathways in neutrophils of patients with acute respiratory distress syndrome. PMID:32282748
Whole-Genome DNA Methylation Profiling of CD14+ Monocytes Reveals Disease Status and Activity Differences in Crohn's Disease Patients. PMID:32276386
Context-Specific Coordinately Regulatory Network Prioritize Breast Cancer Genetic Risk Factors. PMID:32273883
Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis. PMID:32273830
ARID1A Regulates Transcription and the Epigenetic Landscape via POLE and DMAP1 while ARID1A Deficiency or Pharmacological Inhibition Sensitizes Germ Cell Tumor Cells to ATR Inhibition. PMID:32272809
Genome-wide identification of the amino acid permease genes and molecular characterization of their transcriptional responses to various nutrient stresses in allotetraploid rapeseed. PMID:32268885
Test of Arabidopsis Space Transcriptome: A Discovery Environment to Explore Multiple Plant Biology Spaceflight Experiments. PMID:32265943
Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines. PMID:32265286
Evolution of Predicted Acid Resistance Mechanisms in the Extremely Acidophilic Leptospirillum Genus. PMID:32260256
PreMSIm: An R package for predicting microsatellite instability from the expression profiling of a gene panel in cancer. PMID:32257050
Essential gene prediction in Drosophila melanogaster using machine learning approaches based on sequence and functional features. PMID:32257045
Oncogenic Linear Collagen VI of Invasive Breast Cancer Is Induced by CCL5. PMID:32252260
Antibacterial effects of nanopillar surfaces are mediated by cell impedance, penetration and induction of oxidative stress. PMID:32242015
Phosphoproteomic characterization of the signaling network resulting from activation of the chemokine receptor CCR2. PMID:32241914
Development of a prognostic index and screening of potential biomarkers based on immunogenomic landscape analysis of colorectal cancer. PMID:32235004
Evaluation of global gene expression in regenerate tissues during Masquelet treatment. PMID:32233004
MeSHHeading2vec: a new method for representing MeSH headings as vectors based on graph embedding algorithm. PMID:32232320
The sterlet sturgeon genome sequence and the mechanisms of segmental rediploidization. PMID:32231327
Transcriptome analysis reveals the link between lncRNA-mRNA co-expression network and tumor immune microenvironment and overall survival in head and neck squamous cell carcinoma. PMID:32228580
The Joint Analysis of Multi-Omics Data Revealed the Methylation-Expression Regulations in Atrial Fibrillation. PMID:32226785
Endogenous siRNAs promote proteostasis and longevity in germline-less Caenorhabditis elegans. PMID:32213289
Analysis of Dual Class I Histone Deacetylase and Lysine Demethylase Inhibitor Domatinostat (4SC-202) on Growth and Cellular and Genomic Landscape of Atypical Teratoid/Rhabdoid. PMID:32210076
The potential drug for treatment in pancreatic adenocarcinoma: a bioinformatical study based on distinct drug databases. PMID:32206083
Proteomic and Ultrastructural Analysis of Cellulite-New Findings on an Old Topic. PMID:32197394
Pharmacological Mechanisms Underlying the Neuroprotective Effects of Alpinia oxyphylla Miq. on Alzheimer's Disease. PMID:32197305
Identification of hub driving genes and regulators of lung adenocarcinoma based on the gene Co-expression network. PMID:32196072
Identification and validation of HELLS (Helicase, Lymphoid-Specific) and ICAM1 (Intercellular adhesion molecule 1) as potential diagnostic biomarkers of lung cancer. PMID:32195055
FKBP4 is a malignant indicator in luminal A subtype of breast cancer. PMID:32194784
IRF1 association with tumor immune microenvironment and use as a diagnostic biomarker for colorectal cancer recurrence. PMID:32194669
Biglycan as a potential diagnostic and prognostic biomarker in multiple human cancers. PMID:32194659
Integrated Analysis of the Functions and Prognostic Values of RNA Binding Proteins in Lung Squamous Cell Carcinoma. PMID:32194639
The Arabidopsis Proteins AtNHR2A and AtNHR2B Are Multi-Functional Proteins Integrating Plant Immunity With Other Biological Processes. PMID:32194606
A comparative proteomic approach using metabolic pathways for the identification of potential drug targets against Helicobacter pylori. PMID:32193857
Integrated analysis of gene expression and DNA methylation profiles in ovarian cancer. PMID:32192517
Prediction of Side Effects Using Comprehensive Similarity Measures. PMID:32190647
Identification of potential key genes in gastric cancer using bioinformatics analysis. PMID:32190306
Translating traditional herbal formulas into modern drugs: a network-based analysis of Xiaoyao decoction. PMID:32190105
RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination. PMID:32187185
PDGFD induces ibrutinib resistance of diffuse large B‑cell lymphoma through activation of EGFR. PMID:32186759
Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia. PMID:32186681
A Pharmacogenomic Dissection of a Rosuvastatin-Induced Rhabdomyolysis Case Evokes the Polygenic Nature of Adverse Drug Reactions. PMID:32184647
Cyclosporine a directly affects human and mouse b cell migration in vitro by disrupting a hIF-1 αdependent, o2 sensing, molecular switch. PMID:32183695
Heat Stress Impairs the Physiological Responses and Regulates Genes Coding for Extracellular Exosomal Proteins in Rat. PMID:32183190
An Exploratory Gene Expression Study of the Intestinal Mucosa of Patients with Non-Celiac Wheat Sensitivity. PMID:32183058
Tenogenic Contribution to Skeletal Muscle Regeneration: The Secretome of Scleraxis Overexpressing Mesenchymal Stem Cells Enhances Myogenic Differentiation In Vitro. PMID:32183051
Reveals of New Candidate Active Components in Hemerocallis Radix and Its Anti-Depression Action of Mechanism Based on Network Pharmacology Approach. PMID:32182911
Boosting the Biogenesis and Secretion of Mesenchymal Stem Cell-Derived Exosomes. PMID:32182815
Multi-omic analysis of gametogenesis reveals a novel signature at the promoters and distal enhancers of active genes. PMID:32182340
Identification of key genes and pathways of diagnosis and prognosis in cervical cancer by bioinformatics analysis. PMID:32181600
Effects of High-Dose Ionizing Radiation in Human Gene Expression: A Meta-Analysis. PMID:32178397
The construction and analysis of tumor-infiltrating immune cells and ceRNA networks in metastatic adrenal cortical carcinoma. PMID:32175564
FBXW4 Is Highly Expressed and Associated With Poor Survival in Acute Myeloid Leukemia. PMID:32175272
Alternative splicing signatures in preimplantation embryo development. PMID:32175076
Systematic analysis of the basic/helix-loop-helix (bHLH) transcription factor family in pummelo (Citrus grandis) and identification of the key members involved in the response to iron deficiency. PMID:32171259
Machine learning prediction of oncology drug targets based on protein and network properties. PMID:32171238
Comparative Transcriptome-Based Mining and Expression Profiling of Transcription Factors Related to Cold Tolerance in Peanut. PMID:32168930
PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment. PMID:32166339
Proteomic Modulation in the Dorsal Spinal Cord Following Spinal Cord Stimulation Therapy in an In Vivo Neuropathic Pain Model. PMID:32157770
Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B'δ holoenzyme. PMID:32156701
Integrated analysis of gene expression, alteration and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 1 in cancer. PMID:32154045
Functional Characterization of COG1713 (YqeK) as a Novel Diadenosine Tetraphosphate Hydrolase Family. PMID:32152217
Comparative genomics analysis of c-di-GMP metabolism and regulation in Microcystis aeruginosa. PMID:32151246
Bioinformatics Analysis to Screen the Key Prognostic Genes in Tumor Microenvironment of Bladder Cancer. PMID:32149116
Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia. PMID:32146873
Small extracellular vesicles secreted from human amniotic fluid mesenchymal stromal cells possess cardioprotective and promigratory potential. PMID:32146560
A Network-Based Approach to Explore the Mechanisms of Uncaria Alkaloids in Treating Hypertension and Alleviating Alzheimer's Disease. PMID:32143538
The Integrated Transcriptome Bioinformatics Analysis Identifies Key Genes and Cellular Components for Spinal Cord Injury-Related Neuropathic Pain. PMID:32140464
Microenvironment mapping via Dexter energy transfer on immune cells. PMID:32139536
BarleyNet: A Network-Based Functional Omics Analysis Server for Cultivated Barley, Hordeum vulgare L. PMID:32133024
The Potential Role of Selected miRNA in Uveal Melanoma Primary Tumors as Early Biomarkers of Disease Progression. PMID:32131485
Integrative Clustering Reveals a Novel Subtype of Soft Tissue Sarcoma With Poor Prognosis. PMID:32127798
Quantitative proteomics to study aging in rabbit liver. PMID:32126221
Unraveling the genetic causes in large pedigrees with gout by whole‑exome sequencing. PMID:32124961
ChromID identifies the protein interactome at chromatin marks. PMID:32123383
mRNAsi Index: Machine Learning in Mining Lung Adenocarcinoma Stem Cell Biomarkers. PMID:32121037
Integrative Analysis of Methylation and Gene Expression in Lung Adenocarcinoma and Squamous Cell Lung Carcinoma. PMID:32117905
Identification of Therapeutic Targets and Prognostic Biomarkers Among CXC Chemokines in the Renal Cell Carcinoma Microenvironment. PMID:32117786
The Need for SMN-Independent Treatments of Spinal Muscular Atrophy (SMA) to Complement SMN-Enhancing Drugs. PMID:32117013
A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila. PMID:32116515
A white-to-opaque-like phenotypic switch in the yeast Torulaspora microellipsoides. PMID:32111968
DISNET: a framework for extracting phenotypic disease information from public sources. PMID:32110491
Heme Oxygenase-1 and Carbon Monoxide Regulate Growth and Progression in Glioblastoma Cells. PMID:32108290
Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker. PMID:32107344
Role of miRNA-542-5p in the tumorigenesis of osteosarcoma. PMID:32105410
Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma. PMID:32104684
Network Pharmacology-Based Investigation of the System-Level Molecular Mechanisms of the Hematopoietic Activity of Samul-Tang, a Traditional Korean Herbal Formula. PMID:32104198
Integrated Gene Expression Profiling Analysis Reveals Probable Molecular Mechanism and Candidate Biomarker in Anti-TNFα Non-Response IBD Patients. PMID:32104045
The Molecular Mechanism of Perillaldehyde Inducing Cell Death in Aspergillus flavus by Inhibiting Energy Metabolism Revealed by Transcriptome Sequencing. PMID:32102190
Integrated characterization and validation of the prognostic significance of microRNA-200s in colorectal cancer. PMID:32099529
The Genetic Basis of Natural Variation in Drosophila melanogaster Immune Defense against Enterococcus faecalis. PMID:32098395
Detection and characterization of microRNA expression profiling and its target genes in response to canine parvovirus in Crandell Reese Feline Kidney cells. PMID:32095352
Disentangling the genetics of sarcopenia: prioritization of NUDT3 and KLF5 as genes for lean mass & HLA-DQB1-AS1 for hand grip strength with the associated enhancing SNPs & a scoring system. PMID:32093658
Increased Temperature Facilitates Adeno-Associated Virus Vector Transduction of Colorectal Cancer Cell Lines in a Manner Dependent on Heat Shock Protein Signature. PMID:32090115
Transcriptome-wide and differential expression network analyses of childhood asthma in nasal epithelium. PMID:32088307
Development and validation of a RNA binding protein-associated prognostic model for lung adenocarcinoma. PMID:32087603
Bortezomib Treatment Modulates Autophagy in Multiple Myeloma. PMID:32085480
Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast. PMID:32085421
CD44 Loss Disrupts Lung Lipid Surfactant Homeostasis and Exacerbates Oxidized Lipid-Induced Lung Inflammation. PMID:32082314
Identification of biomarkers related to CD8+ T cell infiltration with gene co-expression network in clear cell renal cell carcinoma. PMID:32081834
Changes in nucleus accumbens gene expression accompany sex-specific suppression of spontaneous physical activity in aromatase knockout mice. PMID:32081742
Transposable elements contribute to the genomic response to insecticides in Drosophila melanogaster. PMID:32075557
Identification of prognostic immune-related genes in the tumor microenvironment of endometrial cancer. PMID:32074080
Integrated analysis of the roles and prognostic value of RNA binding proteins in lung adenocarcinoma. PMID:32071816
Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1. PMID:32071079
TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling. PMID:32070329
A systems approach to infectious disease. PMID:32060427
Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions. PMID:32058970
Multi-omics Data Integration for Identifying Osteoporosis Biomarkers and Their Biological Interaction and Causal Mechanisms. PMID:32058959
Analysis of Ras-effector interaction competition in large intestine and colorectal cancer context. PMID:32057289
Integrative proteomic and functional analyses provide novel insights into the action of the repurposed drug candidate nitroxoline in AsPC-1 cells. PMID:32054977
Effect of Grilled Nux Vomica on Differential RNA Expression Profile of Gastrocnemius Muscle and Toll‑Like Receptor 4 (TLR-4)/Nuclear Factor kappa B (NF-κB) Signaling in Experimental Autoimmune Myasthenia Gravis Rats. PMID:32052794
Unmasking Retinitis Pigmentosa complex cases by a whole genome sequencing algorithm based on open-access tools: hidden recessive inheritance and potential oligogenic variants. PMID:32050993
Utilizing Experimental Mouse Model to Identify Effectors of Hepatocellular Carcinoma Induced by HBx Antigen. PMID:32050622
Variability in Gene Expression is Associated with Incomplete Penetrance in Inherited Eye Disorders. PMID:32050448
Screening and Identification of Key Biomarkers for Bladder Cancer: A Study Based on TCGA and GEO Data. PMID:32047816
Bioinformatics analyses on the immune status of renal transplant patients, a systemic research of renal transplantation. PMID:32046717
Comparative Transcriptome Analysis Provides Insights into the Polyunsaturated Fatty Acid Synthesis Regulation of Fat-1 Transgenic Sheep. PMID:32046209
Identification of Potentially Therapeutic Target Genes of Hepatocellular Carcinoma. PMID:32046048
Cholangiocarcinoma: anatomical location-dependent clinical, prognostic, and genetic disparities. PMID:32042760
BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells. PMID:32042152
Physicochemical characterization of Pseudomonas stutzeri UFV5 and analysis of its transcriptome under heterotrophic nitrification/aerobic denitrification pathway induction condition. PMID:32042029
SETD3 acts as a prognostic marker in breast cancer patients and modulates the viability and invasion of breast cancer cells. PMID:32042016
Single-cell RNA sequencing of immune cells in gastric cancer patients. PMID:32039830
Comprehensive Analysis of Competitive Endogenous RNAs Network, Being Associated With Esophageal Squamous Cell Carcinoma and Its Emerging Role in Head and Neck Squamous Cell Carcinoma. PMID:32038997
Analysis of the Differentially Expressed Genes Induced by Cisplatin Resistance in Oral Squamous Cell Carcinomas and Their Interaction. PMID:32038705
Kinobead/LC-MS Phosphokinome Profiling Enables Rapid Analyses of Kinase-Dependent Cell Signaling Networks. PMID:32037842
Comprehensive Analysis of Differential Gene Expression to Identify Common Gene Signatures in Multiple Cancers. PMID:32035007
Integrative Network Analysis of Differentially Methylated and Expressed Genes for Biomarker Identification in Leukemia. PMID:32034170
A Comparative Transcriptome Analysis of Volvariella volvacea Identified the Candidate Genes Involved in Fast Growth at the Mycelial Growth Stage. PMID:32033161
Genetic screens in isogenic mammalian cell lines without single cell cloning. PMID:32029722
Integrative prediction of gene expression with chromatin accessibility and conformation data. PMID:32029002
A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn's disease. PMID:32024964
Discovery of a Gatekeeper Residue in the C-Terminal Tail of the Extracellular Signal-Regulated Protein Kinase 5 (ERK5). PMID:32023819
The Highlighted Role of GAPDH and Nitric-Oxide Synthase Regulator Activity in Proton Beam Irradiated Melanoma BLM Cells. PMID:32021677
The Clinical Significance of PPEF1 as a Promising Biomarker and Its Potential Mechanism in Breast Cancer. PMID:32021267
Isoborneol Attenuates Low-Density Lipoprotein Accumulation and Foam Cell Formation in Macrophages. PMID:32021101
Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors. PMID:32017532
Loss-of-Function Variants in Cytoskeletal Genes Are Associated with Early-Onset Atrial Fibrillation. PMID:32013268
Comprehensive analysis of inhibitor of differentiation/DNA-binding gene family in lung cancer using bioinformatics methods. PMID:32003423
Immune correlates of tuberculosis disease and risk translate across species. PMID:31996462
Metabolic syndrome diminishes insulin-induced Akt activation and causes a redistribution of Akt-interacting proteins in cardiomyocytes. PMID:31995605
Carcinogenesis effects of E2F transcription factor 8 (E2F8) in hepatocellular carcinoma outcomes: an integrated bioinformatic report. PMID:31990034
Proteomic characterization of the normal human medial meniscus body using data-independent acquisition mass spectrometry. PMID:31989678
Highly multiplexed proteomic assessment of human bone marrow in acute myeloid leukemia. PMID:31985806
Combined Effects of Diatom-Derived Oxylipins on the Sea Urchin Paracentrotus lividus. PMID:31979078
Carbonic Anhydrase XII Expression Is Modulated during Epithelial Mesenchymal Transition and Regulated through Protein Kinase C Signaling. PMID:31979064
An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury. PMID:31978079
Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles. PMID:31969990
Integrated bioinformatics analysis to screen hub genes in the lymph node metastasis of thyroid cancer. PMID:31966069
Profiling of human lymphocytes reveals a specific network of protein kinases modulated by endurance training status. PMID:31964936
Methylome and transcriptome analyses reveal insights into the epigenetic basis for the good survival of hypomethylated ER-positive breast cancer subtype. PMID:31959227
Enhanced expression of FCER1G predicts positive prognosis in multiple myeloma. PMID:31956364
Monogenic causes of non-obstructive azoospermia: challenges, established knowledge, limitations and perspectives. PMID:31955275
The ELIXIR Core Data Resources: fundamental infrastructure for the life sciences. PMID:31950984
Molecular Characterization and Expression Profile of PaCOL1, a CONSTANS-like Gene in Phalaenopsis Orchid. PMID:31947959
Identification of Differentially Expressed Proteins in Sugarcane in Response to Infection by Xanthomonas albilineans Using iTRAQ Quantitative Proteomics. PMID:31947808
Domain-mediated interactions for protein subfamily identification. PMID:31937869
Transcriptomic Profiles of Monocyte-Derived Macrophages in Response to Escherichia coli is Associated with the Host Genetics. PMID:31937813
The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. PMID:31932738
Whole blood transcriptomic analysis of beef cattle at arrival identifies potential predictive molecules and mechanisms that indicate animals that naturally resist bovine respiratory disease. PMID:31929561
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance. PMID:31923801
Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo. PMID:31921150
Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC-MS/MS. PMID:31919466
LncRNA XIST serves as a ceRNA to regulate the expression of ASF1A, BRWD1M, and PFKFB2 in kidney transplant acute kidney injury via sponging hsa-miR-212-3p and hsa-miR-122-5p. PMID:31914881
Transcriptome analyses identify hub genes and potential mechanisms in adenoid cystic carcinoma. PMID:31914060
The MyoD family inhibitor domain-containing protein enhances the chemoresistance of cancer stem cells in the epithelial state by increasing β-catenin activity. PMID:31911618
Identification of a CDH12 potential candidate genetic variant for an autosomal dominant form of transgrediens and progrediens palmoplantar keratoderma in a Tunisian family. PMID:31911611
Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy. PMID:31907603
Benchmarking algorithms for gene regulatory network inference from single-cell transcriptomic data. PMID:31907445
Genome-wide analysis reveals the association between alternative splicing and DNA methylation across human solid tumors. PMID:31906954
Modulation of the Liver Protein Carbonylome by the Combined Effect of Marine Omega-3 PUFAs and Grape Polyphenols Supplementation in Rats Fed an Obesogenic High Fat and High Sucrose Diet. PMID:31906027
How to Illuminate the Druggable Genome Using Pharos. PMID:31898878
FNDC3B is associated with ER stress and poor prognosis in cervical cancer. PMID:31897153
Gene expression-based analysis identified NTNG1 and HGF as biomarkers for diabetic kidney disease. PMID:31895808
The dark side of Alzheimer's disease: unstructured biology of proteins from the amyloid cascade signaling pathway. PMID:31894361
Overexpressing PLOD family genes predict poor prognosis in gastric cancer. PMID:31892979
Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relevant tissues with genetic association data. PMID:31891614
The Arabidopsis thaliana N-recognin E3 ligase PROTEOLYSIS1 influences the immune response. PMID:31891113
Proceedings of the EuBIC Winter School 2019. PMID:31890545
The essentiality landscape of cell cycle related genes in human pluripotent and cancer cells. PMID:31889988
Comprehensive analysis of DNA methylation and gene expression profiles in cholangiocarcinoma. PMID:31889904
Based on Integrated Bioinformatics Analysis Identification of Biomarkers in Hepatocellular Carcinoma Patients from Different Regions. PMID:31886176
Small noncoding RNA discovery and profiling with sRNAtools based on high-throughput sequencing. PMID:31885040
Transcription factor regulatory modules provide the molecular mechanisms for functional redundancy observed among transcription factors in yeast. PMID:31881824
Analysis of Differentially Expressed Genes in Coronary Artery Disease by Integrated Microarray Analysis. PMID:31881747
The regulatory effect of microRNA-21a-3p on the promotion of telocyte angiogenesis mediated by PI3K (p110α)/AKT/mTOR in LPS induced mice ARDS. PMID:31878977
Expression and Function of Host Defense Peptides at Inflammation Sites. PMID:31877866
MASS SPECTROMETRY IN VIROLOGICAL SCIENCES. PMID:31876329
Label-Free Quantitative Proteomics Distinguishes General and Site-Specific Host Responses to Pseudomonas aeruginosa Infection at the Ocular Surface. PMID:31874121
Terminal neuron localization to the upper cortical plate is controlled by the transcription factor NEUROD2. PMID:31873146
Increased Prevalence of TG and TPO Mutations in Sudanese Children With Congenital Hypothyroidism. PMID:31867598
Characterization of Human Dosage-Sensitive Transcription Factor Genes. PMID:31867040
PHI-Nets: A Network Resource for Ascomycete Fungal Pathogens to Annotate and Identify Putative Virulence Interacting Proteins and siRNA Targets. PMID:31866958
Transcriptional plasticity buffers genetic variation in zinc homeostasis. PMID:31862901
Functionally Annotating Regulatory Elements in the Equine Genome Using Histone Mark ChIP-Seq. PMID:31861495
Gigantol Targets Cancer Stem Cells and Destabilizes Tumors via the Suppression of the PI3K/AKT and JAK/STAT Pathways in Ectopic Lung Cancer Xenografts. PMID:31861050
Identification of breast cancer risk modules via an integrated strategy. PMID:31860871
Genome-wide assessment of DNA methylation in mouse oocytes reveals effects associated with in vitro growth, superovulation, and sexual maturity. PMID:31856890
Comparative analysis of ascorbate peroxidases (APXs) from selected plants with a special focus on Oryza sativa employing public databases. PMID:31856232
Prognostic significance and molecular mechanisms of adenosine triphosphate-binding cassette subfamily C members in gastric cancer. PMID:31852133
Screening, identification and validation of CCND1 and PECAM1/CD31 for predicting prognosis in renal cell carcinoma patients. PMID:31850854
Human Cerebral Organoids and Fetal Brain Tissue Share Proteomic Similarities. PMID:31850342
The mTOR Signaling Pathway Activity and Vitamin D Availability Control the Expression of Most Autism Predisposition Genes. PMID:31847491
Identification of key genes in non-small cell lung cancer by bioinformatics analysis. PMID:31844590
The landscape and prognostic value of tumor-infiltrating immune cells in gastric cancer. PMID:31844561
Multi-omics analysis of multiple missions to space reveal a theme of lipid dysregulation in mouse liver. PMID:31844325
Identification of Key Genes in Thyroid Cancer Microenvironment. PMID:31839674
MaXLinker: Proteome-wide Cross-link Identifications with High Specificity and Sensitivity. PMID:31839598
Evodiamine Eliminates Colon Cancer Stem Cells via Suppressing Notch and Wnt Signaling. PMID:31835579
Profiles of Long Non-Coding RNAs and mRNA Expression in Human Macrophages Regulated by Interleukin-27. PMID:31835347
Axon-like protrusions promote small cell lung cancer migration and metastasis. PMID:31833833
Induction of PrMADS10 on the lower side of bent pine tree stems: potential role in modifying plant cell wall properties and wood anatomy. PMID:31831838
Mining TCGA Database for Tumor Microenvironment-Related Genes of Prognostic Value in Hepatocellular Carcinoma. PMID:31828095
PPP2R2A prostate cancer haploinsufficiency is associated with worse prognosis and a high vulnerability to B55α/PP2A reconstitution that triggers centrosome destabilization. PMID:31822657
Working the literature harder: what can text mining and bibliometric analysis reveal? PMID:31822126
NF-kappa B Signaling-Related Signatures Are Connected with the Mesenchymal Phenotype of Circulating Tumor Cells in Non-Metastatic Breast Cancer. PMID:31817685
iTRAQ-Based Quantitative Proteomic Analysis of Digestive Juice across the First 48 Hours of the Fifth Instar in Silkworm Larvae. PMID:31817210
Identification of differentially expressed genes in non-small cell lung cancer. PMID:31816603
A Bioinformatic Approach for the Identification of Molecular Determinants of Resistance/Sensitivity to Cancer Thermotherapy. PMID:31814876
The Role of C-X-C Chemokine Receptor Type 4 (CXCR4) in Cell Adherence and Spheroid Formation of Human Ewing's Sarcoma Cells under Simulated Microgravity. PMID:31810195
Expression And Biological Interaction Network Of RHOC For Hepatic Carcinoma With Metastasis In PBMC Samples. PMID:31806997
Identification of prognostic gene signature associated with microenvironment of lung adenocarcinoma. PMID:31803536
Identification of a Tumor Microenvironment-Related Eight-Gene Signature for Predicting Prognosis in Lower-Grade Gliomas. PMID:31803233
The human tissue-resident CCR5+ T cell compartment maintains protective and functional properties during inflammation. PMID:31801887
Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function. PMID:31801617
Identification of Breast Cancer Subtype Specific MicroRNAs Using Survival Analysis to Find Their Role in Transcriptomic Regulation. PMID:31798622
The Complex Genetic Architecture of Early Root and Shoot Traits in Flax Revealed by Genome-Wide Association Analyses. PMID:31798617
Pathway and network embedding methods for prioritizing psychiatric drugs. PMID:31797637
Graph-based information diffusion method for prioritizing functionally related genes in protein-protein interaction networks. PMID:31797617
Peripheral blood mononuclear cell transcriptomes reveal an over-representation of down-regulated genes associated with immunity in HIV-exposed uninfected infants. PMID:31792230
Phenotypic proteomic profiling identifies a landscape of targets for circadian clock-modulating compounds. PMID:31792063
A novel prognostic nomogram based on 5 long non-coding RNAs in clear cell renal cell carcinoma. PMID:31788117
High gene expression levels of VEGFA and CXCL8 in the peritumoral brain zone are associated with the recurrence of glioblastoma: A bioinformatics analysis. PMID:31788092
Identification of the lncRNA-miRNA-mRNA network associated with gastric cancer via integrated bioinformatics analysis. PMID:31788050
Sex-Based Analysis of De Novo Variants in Neurodevelopmental Disorders. PMID:31785789
Data Mining of Prognostic Microenvironment-Related Genes in Clear Cell Renal Cell Carcinoma: A Study with TCGA Database. PMID:31781309
Eggplant Germination is Promoted by Hydrogen Peroxide and Temperature in an Independent but Overlapping Manner. PMID:31771170
Salivary Protein Panel to Diagnose Systolic Heart Failure. PMID:31766659
Bioinformatics analyses of publicly available NEPCa datasets. PMID:31763364
Genome-wide scans identify known and novel regions associated with prolificacy and reproduction traits in a sub-Saharan African indigenous sheep (Ovis aries). PMID:31758253
An epigenetic screening determines BET proteins as targets to suppress self-renewal and tumorigenicity in canine mammary cancer cells. PMID:31758045
Monocytes affect bone mineral density in pre- and postmenopausal women through ribonucleoprotein complex biogenesis by integrative bioinformatics analysis. PMID:31754224
Dissecting the Regulatory Network of Leaf Premature Senescence in Maize (Zea mays L.) Using Transcriptome Analysis of ZmELS5 Mutant. PMID:31752425
Impact of Nitrogen Nutrition on Cannabis sativa: An Update on the Current Knowledge and Future Prospects. PMID:31752217
Identification of novel blood biomarkers of treatment response in cystic fibrosis pulmonary exacerbations by label-free quantitative proteomics. PMID:31748618
A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants. PMID:31745173
LncRNA SNHG8 is identified as a key regulator of acute myocardial infarction by RNA-seq analysis. PMID:31739782
BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome. PMID:31738183
The transcriptome difference between colorectal tumor and normal tissues revealed by single-cell sequencing. PMID:31737124
Characterization of Matricellular Protein Expression Signatures in Mechanistically Diverse Mouse Models of Kidney Injury. PMID:31723159
TNF-α induces acyl-CoA synthetase 3 to promote lipid droplet formation in human endothelial cells. PMID:31722970
Neuro-Inflammation in Pediatric Traumatic Brain Injury-from Mechanisms to Inflammatory Networks. PMID:31717597
Genetic Modifiers at the Crossroads of Personalised Medicine for Haemoglobinopathies. PMID:31717530
The Role of Nrf2 Activity in Cancer Development and Progression. PMID:31717324
Coagulation FXIII-A Protein Expression Defines Three Novel Sub-populations in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia Characterized by Distinct Gene Expression Signatures. PMID:31709175
Further Elucidation of the Argonaute and Dicer Protein Families in the Model Grass Species Brachypodium distachyon. PMID:31708948
PAC-5 Gene Expression Signature for Predicting Prognosis of Patients with Pancreatic Adenocarcinoma. PMID:31703415
Targeting Epithelial Mesenchymal Plasticity in Pancreatic Cancer: A Compendium of Preclinical Discovery in a Heterogeneous Disease. PMID:31703358
An in Vitro Selection Strategy Identifying Naked DNA That Localizes to Cell Nuclei. PMID:31702902
The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species. PMID:31701156
Induction of Lysosome-associated Protein Transmembrane 4 Beta via Sulfatase 2 Enhances Autophagic Flux in Liver Cancer Cells. PMID:31701075
Co-regulation map of the human proteome enables identification of protein functions. PMID:31690884
Cisplatin-resistant triple-negative breast cancer subtypes: multiple mechanisms of resistance. PMID:31684899
The Construction and Analysis of ceRNA Network and Patterns of Immune Infiltration in Mesothelioma With Bone Metastasis. PMID:31681739
ChimerDB 4.0: an updated and expanded database of fusion genes. PMID:31680157
Proteomic changes in the milk of water buffaloes (Bubalus bubalis) with subclinical mastitis due to intramammary infection by Staphylococcus aureus and by non-aureus staphylococci. PMID:31676851
Role of alternative splicing signatures in the prognosis of glioblastoma. PMID:31674730
Meta-Analysis of Polymyositis and Dermatomyositis Microarray Data Reveals Novel Genetic Biomarkers. PMID:31671645
Identification of hub genes and small-molecule compounds related to intracerebral hemorrhage with bioinformatics analysis. PMID:31667013
ProteomicsDB: a multi-omics and multi-organism resource for life science research. PMID:31665479
ChlamDB: a comparative genomics database of the phylum Chlamydiae and other members of the Planctomycetes-Verrucomicrobiae-Chlamydiae superphylum. PMID:31665454
Liver kinase B1 depletion from astrocytes worsens disease in a mouse model of multiple sclerosis. PMID:31664743
Acute exposure to nocturnal train noise induces endothelial dysfunction and pro-thromboinflammatory changes of the plasma proteome in healthy subjects. PMID:31664594
The ribosome assembly factor Nop53 controls association of the RNA exosome with pre-60S particles in yeast. PMID:31662437
Phenome-wide association study of TTR and RBP4 genes in 361,194 individuals reveals novel insights in the genetics of hereditary and wildtype transthyretin amyloidoses. PMID:31659433
Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1. PMID:31659178
Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development. PMID:31652801
Hyperacetylation of Cardiac Mitochondrial Proteins Is Associated with Metabolic Impairment and Sirtuin Downregulation after Chronic Total Body Irradiation of ApoE -/- Mice. PMID:31652604
Hypergraph-based connectivity measures for signaling pathway topologies. PMID:31652258
Redefining malignant pleural mesothelioma types as a continuum uncovers immune-vascular interactions. PMID:31648983
Plasma membrane receptor-like kinases and transporters are associated with 2,4-D resistance in wild radish. PMID:31646341
Network Pharmacology Reveals the Molecular Mechanism of Cuyuxunxi Prescription in Promoting Wound Healing in Patients with Anal Fistula. PMID:31636684
Effects of Iron Oxide Nanoparticles (γ-Fe2O3) on Liver, Lung and Brain Proteomes following Sub-Acute Intranasal Exposure: A New Toxicological Assessment in Rat Model Using iTRAQ-Based Quantitative Proteomics. PMID:31635106
RNA-Seq analysis of ileocecal valve and peripheral blood from Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis revealed dysregulation of the CXCL8/IL8 signaling pathway. PMID:31619718
Biological Network Approaches and Applications in Rare Disease Studies. PMID:31614842
Long non-coding RNA small nucleolar RNA host gene 7 is upregulated and promotes cell proliferation in thyroid cancer. PMID:31611982
Phylogenetic correlations can suffice to infer protein partners from sequences. PMID:31609984
The Construction and Comprehensive Analysis of ceRNA Networks and Tumor-Infiltrating Immune Cells in Bone Metastatic Melanoma. PMID:31608101
VarSite: Disease variants and protein structure. PMID:31606900
Differential impact of classical and non-canonical NF-κB pathway-related gene expression on the survival of breast cancer patients. PMID:31602271
Smoking alters the evolutionary trajectory of non-small cell lung cancer. PMID:31602204
Genome-wide investigation of superoxide dismutase (SOD) gene family and their regulatory miRNAs reveal the involvement in abiotic stress and hormone response in tea plant (Camellia sinensis). PMID:31600284
BiomeNet: a database for construction and analysis of functional interaction networks for any species with a sequenced genome. PMID:31599923
Asparagine Deprivation Causes a Reversible Inhibition of Human Cytomegalovirus Acute Virus Replication. PMID:31594813
Molecular analysis of an enigmatic Streptococcus pneumoniae virulence factor: The raffinose-family oligosaccharide utilization system. PMID:31591266
Role of miR-10b-5p in the prognosis of breast cancer. PMID:31579605
Integrin α-5 as a potential biomarker of head and neck squamous cell carcinoma. PMID:31579416
FGB and FGG derived from plasma exosomes as potential biomarkers to distinguish benign from malignant pulmonary nodules. PMID:31576477
Navigating the dynamic landscape of alpha-synuclein morphology: a review of the physiologically relevant tetrameric conformation. PMID:31571649
Overexpression of GmCAMTA12 Enhanced Drought Tolerance in Arabidopsis and Soybean. PMID:31569565
Integration of Bioinformatics Resources Reveals the Therapeutic Benefits of Gemcitabine and Cell Cycle Intervention in SMAD4-Deleted Pancreatic Ductal Adenocarcinoma. PMID:31569425
Enhancing cardiac glycolysis causes an increase in PDK4 content in response to short-term high-fat diet. PMID:31562244
Polyamine Synthesis Effects Capsule Expression by Reduction of Precursors in Streptococcus pneumoniae. PMID:31555234
Serum-Derived Extracellular Vesicles from African Swine Fever Virus-Infected Pigs Selectively Recruit Viral and Porcine Proteins. PMID:31547130
Identification of Aloperine as an anti-apoptotic Bcl2 protein inhibitor in glioma cells. PMID:31534865
Altered Fecal Small RNA Profiles in Colorectal Cancer Reflect Gut Microbiome Composition in Stool Samples. PMID:31530647
Prognostic significance of TOP2A in non-small cell lung cancer revealed by bioinformatic analysis. PMID:31528121
Association between promoter DNA methylation and gene expression in the pathogenesis of ischemic stroke. PMID:31527307
Profiling the lncRNA-miRNA-mRNA ceRNA network to reveal potential crosstalk between inflammatory bowel disease and colorectal cancer. PMID:31523496
Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity. PMID:31521608
Bioinformatics and functional analyses of key genes in smoking-associated lung adenocarcinoma. PMID:31516576
Global Transcriptomic Analysis of the Candida albicans Response to Treatment with a Novel Inhibitor of Filamentation. PMID:31511371
Clinical, pathophysiologic, and genomic analysis of the outcomes of primary head and neck malignancy after pulmonary metastasectomy. PMID:31501464
Identification of Transcriptional Markers and microRNA-mRNA Regulatory Networks in Colon Cancer by Integrative Analysis of mRNA and microRNA Expression Profiles in Colon Tumor Stroma. PMID:31500382
A six-gene-based prognostic model predicts complete remission and overall survival in childhood acute myeloid leukemia. PMID:31496748
Bioinformatic evidences and analysis of putative biomarkers in pancreatic ductal adenocarcinoma. PMID:31489384
The Spectrinome: The Interactome of a Scaffold Protein Creating Nuclear and Cytoplasmic Connectivity and Function. PMID:31483159
Structures of the substrate-binding protein YfeA in apo and zinc-reconstituted holo forms. PMID:31478906
Autograft microskin combined with adipose-derived stem cell enhances wound healing in a full-thickness skin defect mouse model. PMID:31470890
SILAC-Based Quantification of TGFBR2-Regulated Protein Expression in Extracellular Vesicles of Microsatellite Unstable Colorectal Cancers. PMID:31454892
Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration. PMID:31451657
Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial-mesenchymal transition and subcellular re-localization of Beta-Catenin. PMID:31448663
Identification of microRNA-181 as a promising biomarker for predicting the poor survival in colorectal cancer. PMID:31448575
P2X7 Interactions and Signaling - Making Head or Tail of It. PMID:31440138
Replication timing networks reveal a link between transcription regulatory circuits and replication timing control. PMID:31434679
The identification of CRNDE, H19, UCA1 and HOTAIR as the key lncRNAs involved in oxaliplatin or irinotecan resistance in the chemotherapy of colorectal cancer based on integrative bioinformatics analysis. PMID:31432188
Consistent Biomarkers and Related Pathogenesis Underlying Asthma Revealed by Systems Biology Approach. PMID:31430856
Development and validation of an interferon signature predicting prognosis and treatment response for glioblastoma. PMID:31428519
Deciphering GRINA/Lifeguard1: Nuclear Location, Ca2+ Homeostasis and Vesicle Transport. PMID:31426446
Vestigial like family member 3 is a novel prognostic biomarker for gastric cancer. PMID:31423427
Atypical cyclins: the extended family portrait. PMID:31420702
Reverse vaccinology and subtractive genomics reveal new therapeutic targets against Mycoplasma pneumoniae: a causative agent of pneumonia. PMID:31417766
Transcriptomic Analysis of Porcine Granulosa Cells Overexpressing Retinol Binding Protein 4. PMID:31412686
Up-regulation of SPC25 promotes breast cancer. PMID:31400751
In Silico Phylogenetic and Structural Analyses of Plant Endogenous Danger Signaling Molecules upon Stress. PMID:31396307
Proteomic Analysis of Antigen 60 Complex of M. bovis Bacillus Calmette-Guérin Reveals Presence of Extracellular Vesicle Proteins and Predicted Functional Interactions. PMID:31382538
Investigation of Extracellular Matrix Protein Expression Dynamics Using Murine Models of Systemic Inflammation. PMID:31376095
The establishment of immune infiltration based novel recurrence predicting nomogram in prostate cancer. PMID:31355524
Transcriptomes in rat sciatic nerves at different stages of experimental autoimmune neuritis determined by RNA sequencing. PMID:31344254
Meta-Analysis of Gene Expression and Identification of Biological Regulatory Mechanisms in Alzheimer's Disease. PMID:31333395
Induction of Acquired Resistance towards EGFR Inhibitor Gefitinib in a Patient-Derived Xenograft Model of Non-Small Cell Lung Cancer and Subsequent Molecular Characterization. PMID:31323891
The analysis of miRNA expression profiling datasets reveals inverse microRNA patterns in glioblastoma and Alzheimer's disease. PMID:31322245
Proteomic Identification and Time-Course Monitoring of Secreted Proteins During Expansion of Human Mesenchymal Stem/Stromal in Stirred-Tank Bioreactor. PMID:31297369
Differential determinants of virulence in two Mycobacterium tuberculosis Colombian clinical isolates of the LAM09 family. PMID:31291814
The construction and analysis of the aberrant lncRNA-miRNA-mRNA network in non-small cell lung cancer. PMID:31285869
Potential Role of Rainbow Trout Erythrocytes as Mediators in the Immune Response Induced by a DNA Vaccine in Fish. PMID:31277329
Exploring the dark genome: implications for precision medicine. PMID:31270560
HyperFoods: Machine intelligent mapping of cancer-beating molecules in foods. PMID:31270435
Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens. PMID:31266803
Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations. PMID:31249065
Genome-Wide Analysis of Serine/Arginine-Rich Protein Family in Wheat and Brachypodium distachyon. PMID:31247888
Proteomics Approaches for Biomarker and Drug Target Discovery in ALS and FTD. PMID:31244593
Anticancer Effects of Emodin on HepG2 Cell: Evidence from Bioinformatic Analysis. PMID:31236404
Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids. PMID:31204303
Extracellular vesicles from osteosarcoma cell lines contain miRNAs associated with cell adhesion and apoptosis. PMID:31176732
Genome-Wide Identification of Na+/H+ Antiporter (NHX) Genes in Sugar Beet (Beta vulgaris L.) and Their Regulated Expression under Salt Stress. PMID:31137880
Insights into the loss of the Y chromosome with age in control individuals and in patients with age-related macular degeneration using genotyping microarray data. PMID:31134332
Geneshot: search engine for ranking genes from arbitrary text queries. PMID:31114885
modEnrichr: a suite of gene set enrichment analysis tools for model organisms. PMID:31069376
Revisiting the Role of Transcription Factors in Coordinating the Defense Response Against Citrus Bark Cracking Viroid Infection in Commercial Hop (Humulus Lupulus L.). PMID:31060295
Identification of Novel MicroRNAs and Their Diagnostic and Prognostic Significance in Oral Cancer. PMID:31052345
LncRNA-SULT1C2A regulates Foxo4 in congenital scoliosis by targeting rno-miR-466c-5p through PI3K-ATK signalling. PMID:31044535
Differentially expressed circulating miRNAs in postmenopausal osteoporosis: a meta-analysis. PMID:31023966
EPAS 1, congenital heart disease, and high altitude: disclosures by genetics, bioinformatics, and experimental embryology. PMID:31015364
TRIAD3/RNF216 E3 ligase specifically synthesises K63-linked ubiquitin chains and is inactivated by mutations associated with Gordon Holmes syndrome. PMID:30886743
The 26th annual Nucleic Acids Research database issue and Molecular Biology Database Collection. PMID:30626175 -
STRING v10: protein-protein interaction networks, integrated over the tree of life
PubMed citations: 4315.
4315 articles citing: STRING v10: protein-protein interaction networks, integrated over the tree of life
Genome-wide identification of long non-coding (lncRNA) in Nilaparvata lugens's adaptability to resistant rice. PMID:35910769
Exploration and validation of metastasis-associated genes for skin cutaneous melanoma. PMID:35906389
Fibronectin Modulates the Expression of miRNAs in Prostate Cancer Cell Lines. PMID:35898539
Remarkable immune and clinical value of novel ferroptosis-related genes in glioma. PMID:35896732
Gene Expression Characteristics of Tumor and Adjacent Non-Tumor Tissues of Pancreatic Ductal Adenocarcinoma (PDAC) In-Silico. PMID:35891953
Update and elucidation of Plasmodium kinomes: Prioritization of kinases as potential drug targets for malaria. PMID:35891792
Transcriptome Analysis Reveals Molecular Mechanisms under Salt Stress in Leaves of Foxtail Millet (Setaria italica L.). PMID:35890498
Potential Cross Talk between Autism Risk Genes and Neurovascular Molecules: A Pilot Study on Impact of Blood Brain Barrier Integrity. PMID:35883654
The Culture Dish Surface Influences the Phenotype and Dissociation Strategy in Distinct Mouse Macrophage Populations. PMID:35874686
SNP-to-gene linking strategies reveal contributions of enhancer-related and candidate master-regulator genes to autoimmune disease. PMID:35873673
In-Silico Study of Brassinosteroid Signaling Genes in Rice Provides Insight Into Mechanisms Which Regulate Their Expression. PMID:35873468
Hub Gene Screening Associated with Early Glaucoma: An Integrated Bioinformatics Analysis. PMID:35872944
Identifying patterns of immune related cells and genes in the peripheral blood of acute myocardial infarction patients using a small cohort. PMID:35864510
Effect of the FA2H Gene on cashmere fineness of Jiangnan cashmere goats based on transcriptome sequencing. PMID:35864447
Network Pharmacology-Based Prediction and Pharmacological Validation of Effects of Astragali Radix on Acetaminophen-Induced Liver Injury. PMID:35860733
Identification of Ferroptosis-Associated Genes in Prostate Cancer by Bioinformatics Analysis. PMID:35860472
Comprehensive Computational Analysis of Honokiol Targets for Cell Cycle Inhibition and Immunotherapy in Metastatic Breast Cancer Stem Cells. PMID:35845599
Bioinformatics role of the WGCNA analysis and co-expression network identifies of prognostic marker in lung cancer. PMID:35844396
One-Week Dynamic Changes in Cardiac Proteomes After Cardiac Radioablation in Experimental Rat Model. PMID:35837601
Hub Gene Screening and Prognostic Modeling of Lung Cancer: An Integrated Bioinformatics Study. PMID:35836920
Multi-omics study identifies novel signatures of DNA/RNA, amino acid, peptide, and lipid metabolism by simulated diabetes on coronary endothelial cells. PMID:35835939
Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis. PMID:35835912
Aberrant Gene Expression Profiling in Men With Sertoli Cell-Only Syndrome. PMID:35833143
DriverRWH: discovering cancer driver genes by random walk on a gene mutation hypergraph. PMID:35831792
ANGPTL4 regulates the osteogenic differentiation of periodontal ligament stem cells. PMID:35831768
Searching for G-Quadruplex-Binding Proteins in Plants: New Insight into Possible G-Quadruplex Regulation. PMID:35822794
NUF2 Expression Promotes Lung Adenocarcinoma Progression and Is Associated With Poor Prognosis. PMID:35814368
Pericyte-derived extracellular vesicle-mimetic nanovesicles ameliorate erectile dysfunction via lipocalin 2 in diabetic mice. PMID:35813481
Suppressing MDSC Infiltration in Tumor Microenvironment Serves as an Option for Treating Ovarian Cancer Metastasis. PMID:35813475
Identification of Hub Genes and Immune-Related Pathways for Membranous Nephropathy by Bioinformatics Analysis. PMID:35812314
Biocompatibility of ZrO2 vs. Y-TZP Alloys: Influence of Their Composition and Surface Topography. PMID:35806779
A Set of Dysregulated Target Genes to Reduce Neuroinflammation at Molecular Level. PMID:35806178
Dynamics of Protein Phosphorylation during Arabidopsis Seed Germination. PMID:35806063
Haptoglobin Induces a Specific Proteomic Profile and a Mature-Associated Phenotype on Primary Human Monocyte-Derived Dendritic Cells. PMID:35805888
Novel Drug Candidate Prediction for Intrahepatic Cholangiocarcinoma via Hub Gene Network Analysis and Connectivity Mapping. PMID:35805055
Genetic association and single-cell transcriptome analyses reveal distinct features connecting autoimmunity with cancers. PMID:35800769
A Novel Drug Combination of Mangiferin and Cinnamic Acid Alleviates Rheumatoid Arthritis by Inhibiting TLR4/NFκB/NLRP3 Activation-Induced Pyroptosis. PMID:35799788
Potential biomarkers for inflammatory response in acute lung injury. PMID:35795000
Comprehensive Evaluation of the m6A Regulator Prognostic Risk Score in the Prediction of Immunotherapy Response in Clear Cell Renal Cell Carcinoma. PMID:35784363
A Pan-Cancer Analysis Revealing the Dual Roles of Lysine (K)-Specific Demethylase 6B in Tumorigenesis and Immunity. PMID:35783266
Proteomic Analysis of Chicken Chorioallantoic Membrane (CAM) during Embryonic Development Provides Functional Insight. PMID:35774275
YAP1 induces invadopodia formation by transcriptionally activating TIAM1 through enhancer in breast cancer. PMID:35773411
The close interaction between hypoxia-related proteins and metastasis in pancarcinomas. PMID:35773405
INK4 cyclin-dependent kinase inhibitors as potential prognostic biomarkers and therapeutic targets in hepatocellular carcinoma. PMID:35771229
Analysis of Omics Data Reveals Nucleotide Excision Repair-Related Genes Signature in Highly-Grade Serous Ovarian Cancer to Predict Prognosis. PMID:35769257
Comparative transcriptome analysis of Indian domestic duck reveals candidate genes associated with egg production. PMID:35768515
A timeseries analysis of the fracture callus extracellular matrix proteome during bone fracture healing. PMID:35765657
The genomic basis of the plant island syndrome in Darwin's giant daisies. PMID:35764640
IL-17A deletion reduces sevoflurane-induced neurocognitive impairment in neonatal mice by inhibiting NF-κB signaling pathway. PMID:35758051
Fat Attenuation Index of Renal Cell Carcinoma Reveals Biological Characteristics and Survival Outcome. PMID:35756650
Link Prediction on Complex Networks: An Experimental Survey. PMID:35754861
The Novel lncRNA ENST00000530525 Affects ANO1, Contributing to Blood-Brain Barrier Injury in Cultured hCMEC/D3 Cells Under OGD/R Conditions. PMID:35754821
Network Pharmacology Approach to Investigate the Mechanism of Modified Liu Jun Zi Decoction in the Treatment of Chronic Atrophic Gastritis. PMID:35754680
Pathway importance by graph convolutional network and Shapley additive explanations in gene expression phenotype of diffuse large B-cell lymphoma. PMID:35749395
An Integrated Mass Spectrometry-Based Glycomics-Driven Glycoproteomics Analytical Platform to Functionally Characterize Glycosylation Inhibitors. PMID:35744954
Transcriptome and Metabolome Analysis of Upland Cotton (Gossypium hirsutum) Seed Pretreatment with MgSO4 in Response to Salinity Stress. PMID:35743952
Dysregulated Brain Protein Phosphorylation Linked to Increased Human Tau Expression in the hTau Transgenic Mouse Model. PMID:35742871
Profiling the Tumor-Infiltrating Lymphocytes in Gastric Cancer Reveals Its Implication in the Prognosis. PMID:35741779
Exploration of the Common Gene Characteristics and Molecular Mechanism of Parkinson's Disease and Crohn's Disease from Transcriptome Data. PMID:35741659
Identifying the Potential Roles of PBX4 in Human Cancers Based on Integrative Analysis. PMID:35740947
Unique SMYD5 Structure Revealed by AlphaFold Correlates with Its Functional Divergence. PMID:35740908
Network pharmacology integrated molecular dynamics reveals the bioactive compounds and potential targets of Tinospora crispa Linn. as insulin sensitizer. PMID:35737707
Enhanced Carbonylation of Photosynthetic and Glycolytic Proteins in Antibiotic Timentin-Treated Tobacco In Vitro Shoot Culture. PMID:35736723
A Common Polymorphism in the MTHFD1 Gene Is a Modulator of Risk of Congenital Heart Disease. PMID:35735795
Integrated Bioinformatics Analysis for Identifying the Significant Genes as Poor Prognostic Markers in Gastric Adenocarcinoma. PMID:35726219
Screening and Identification of Hub Genes in the Development of Early Diabetic Kidney Disease Based on Weighted Gene Co-Expression Network Analysis. PMID:35721731
Integration of Transcriptomics Data and Metabolomic Data Using Biomedical Literature Mining and Pathway Analysis. PMID:35713871
Renal tubular gen e biomarkers identification based on immune infiltrates in focal segmental glomerulosclerosis. PMID:35713363
Identification of an Endoplasmic Reticulum Stress-Related Gene Signature to Evaluate the Immune Status and Predict the Prognosis of Hepatocellular Carcinoma. PMID:35711939
ORC6 acts as a biomarker and reflects poor outcome in clear cell renal cell carcinoma. PMID:35711825
The Underlying Molecular Basis and Mechanisms of Venous Thrombosis in Patients with Osteomyelitis: A Data-Driven Analysis. PMID:35711689
Mechanisms of Quercetin against atrial fibrillation explored by network pharmacology combined with molecular docking and experimental validation. PMID:35697725
Multi-Omics Analysis of MCM2 as a Promising Biomarker in Pan-Cancer. PMID:35693940
Identification of Four Novel Prognostic Biomarkers and Construction of Two Nomograms in Adrenocortical Carcinoma: A Multi-Omics Data Study via Bioinformatics and Machine Learning Methods. PMID:35693556
A Random Forest-Based Genome-Wide Scan Reveals Fertility-Related Candidate Genes and Potential Inter-Chromosomal Epistatic Regions Associated With Age at First Calving in Nellore Cattle. PMID:35692843
Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis. PMID:35692536
Characterization of m6A Methylation Modification Patterns in Colorectal Cancer Determines Prognosis and Tumor Microenvironment Infiltration. PMID:35692505
Label-free quantitative proteomic analysis of serum exosomes from patients of renal anemia: The Good and the Bad of Roxadustat. PMID:35690731
A ferrocene-containing nucleoside analogue targets DNA replication in pancreatic cancer cells. PMID:35689667
miR-375 is cold exposure sensitive and drives thermogenesis in visceral adipose tissue derived stem cells. PMID:35688898
Computational identification of protein complexes from network interactions: Present state, challenges, and the way forward. PMID:35685359
The dynamic cellular and molecular features during the development of radiation proctitis revealed by transcriptomic profiling in mice. PMID:35681125
Posttranscriptional Regulation in Response to Different Environmental Stresses in Campylobacter jejuni. PMID:35678555
Identification of prognostic candidate signatures by systematically revealing transcriptome characteristics in lung adenocarcinoma with differing tumor microenvironment immune phenotypes. PMID:35675043
Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes. PMID:35672324
A Multiomics Profiling Based on Online Database Revealed Prognostic Biomarkers of BLCA. PMID:35669725
Identification of Hub Genes Associated with Nonspecific Orbital Inflammation by Weighted Gene Coexpression Network Analysis. PMID:35669499
Identification of the Active Compound of Liu Wei Di Huang Wan for Treatment of Gestational Diabetes Mellitus via Network Pharmacology and Molecular Docking. PMID:35669396
Identifying the critical states and dynamic network biomarkers of cancers based on network entropy. PMID:35668489
Solute carrier family 2 members 1 and 2 as prognostic biomarkers in hepatocellular carcinoma associated with immune infiltration. PMID:35665115
Three Prognostic Biomarkers Correlate with Immune Checkpoint Blockade Response in Bladder Urothelial Carcinoma. PMID:35664691
NAP1L1 Functions as a Novel Prognostic Biomarker Associated With Macrophages and Promotes Tumor Progression by Influencing the Wnt/β-Catenin Pathway in Hepatocellular Carcinoma. PMID:35664324
miRNA-432 and SLC38A1 as Predictors of Hepatocellular Carcinoma Complicated with Alcoholic Steatohepatitis. PMID:35663198
Reduced serum high-density lipoprotein cholesterol levels and aberrantly expressed cholesterol metabolism genes in colorectal cancer. PMID:35663062
Screening the hub genes and analyzing the mechanisms in discharged COVID-19 patients retesting positive through bioinformatics analysis. PMID:35657140
Integrative Analysis of KCNK Genes and Establishment of a Specific Prognostic Signature for Breast Cancer. PMID:35656548
Bioinformatics Study Identified EGF as a Crucial Gene in Papillary Renal Cell Cancer. PMID:35655917
Identifying Functions of Proteins in Mice With Functional Embedding Features. PMID:35651937
BARD1 mystery: tumor suppressors are cancer susceptibility genes. PMID:35650591
Key Genes Identified in Nonsyndromic Microtia by the Analysis of Transcriptomics and Proteomics. PMID:35647449
Cell-Based HIF1α Gene Therapy Reduces Myocardial Scar and Enhances Angiopoietic Proteome, Transcriptomic and miRNA Expression in Experimental Chronic Left Ventricular Dysfunction. PMID:35646882
Identification of a Cancer Stem Cells Signature of Head and Neck Squamous Cell Carcinoma. PMID:35646104
Comparative Transcriptome Analysis of Gingival Immune-Mediated Inflammation in Peri-Implantitis and Periodontitis Within the Same Host Environment. PMID:35642216
Molecular Interactions Associated with Oxidative Stress-Mediated Male Infertility: Sperm and Seminal Plasma Proteomics. PMID:35641866
Characteristics of alveolar macrophages in bronchioalveolar lavage fluids from active tuberculosis patients identified by single-cell RNA sequencing. PMID:35635159
Novel Mutations in ACP5 and SAMHD1 in a Patient With Pediatric Systemic Lupus Erythematosus. PMID:35633950
A Crucial Angiogenesis-Associated Gene MEOX2 Could Be a Promising Biomarker Candidate for Breast Cancer. PMID:35615155
A Novel Immune-Prognosis Index Predicts the Benefit of Lung Adenocarcinoma Patients. PMID:35614936
Identification of vaccine targets & design of vaccine against SARS-CoV-2 coronavirus using computational and deep learning-based approaches. PMID:35611169
Identification and expression analysis of the CqSnRK2 gene family and a functional study of the CqSnRK2.12 gene in quinoa (Chenopodium quinoa Willd.). PMID:35610576
OrthoQuantum: visualizing evolutionary repertoire of eukaryotic proteins. PMID:35610035
Transcriptome analysis reveals high tumor heterogeneity with respect to re-activation of stemness and proliferation programs. PMID:35587924
Analysis of Multifactor-Driven Myopia Disease Modules to Guide Personalized Treatment and Drug Development. PMID:35586671
New biomarker: the gene HLA-DRA associated with low-grade glioma prognosis. PMID:35585639
Visual barcodes for clonal-multiplexing of live microscopy-based assays. PMID:35585055
Bioinformatics network analyses of growth differentiation factor 11. PMID:35582621
GLIDER: Function Prediction from GLIDE-based Neigborhoods. PMID:35575379
Identification of major candidate genes for multiple abiotic stress tolerance at seedling stage by network analysis and their validation by expression profiling in rice (Oryza sativa L.). PMID:35573803
Identification of significant genes with a poor prognosis in skin cutaneous malignant melanoma based on a bioinformatics analysis. PMID:35571409
Time-Restricted Eating Regimen Differentially Affects Circulatory miRNA Expression in Older Overweight Adults. PMID:35565812
Potential Biomarkers and Drugs for Nanoparticle-Induced Cytotoxicity in the Retina: Based on Regulation of Inflammatory and Apoptotic Genes. PMID:35565057
FKBP51, AmotL2 and IQGAP1 Involvement in Cilastatin Prevention of Cisplatin-Induced Tubular Nephrotoxicity in Rats. PMID:35563891
Non-Cytokine Protein Profile of the Mesenchymal Stem Cell Secretome That Regulates the Androgen Production Pathway. PMID:35563028
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors. PMID:35559673
14,15-Epoxyeicosatrienoic Acid Protect Against Glucose Deprivation and Reperfusion-Induced Cerebral Microvascular Endothelial Cells Injury by Modulating Mitochondrial Autophagy via SIRT1/FOXO3a Signaling Pathway and TSPO Protein. PMID:35558879
Proteomic characterization of four subtypes of M2 macrophages derived from human THP-1 cells. PMID:35557041
An Herbal Product Alleviates Bleomycin-Induced Pulmonary Fibrosis in Mice via Regulating NF-κB/TNF-α Signaling in Macrophages. PMID:35548340
Artificial intelligence in cancer target identification and drug discovery. PMID:35538061
A novel lncRNA-miRNA-mRNA triple network identifies lncRNA XIST as a biomarker for acute myocardial infarction. PMID:35537778
In Silico Identification of Hub Genes as Observing Biomarkers for Gastric Cancer Metastasis. PMID:35535159
The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function. PMID:35534539
Mining the prognostic significance and immune infiltration of STAT family members in human breast cancer by bioinformatics analysis. PMID:35531108
Network Pharmacology and Comparative Transcriptome Reveals Biotargets and Mechanisms of Curcumol Treating Lung Adenocarcinoma Patients With COVID-19. PMID:35520289
Biallelic ATOH1 Gene Variant in Siblings With Pontocerebellar Hypoplasia, Developmental Delay, and Hearing Loss. PMID:35518571
LINC00922 promotes deterioration of gastric cancer. PMID:35511773
RNA-seq based integrative analysis of potential crucial genes and pathways associated with patellar instability. PMID:35510414
Potential Small Molecules for Therapy of Lupus Nephritis Based on Genetic Effect and Immune Infiltration. PMID:35502341
The Mechanism of Dendrobium officinale as a Treatment for Hyperlipidemia Based on Network Pharmacology and Experimental Validation. PMID:35502176
Characterization of cell-cell communication in autistic brains with single-cell transcriptomes. PMID:35501678
Pathophysiological pathway differences in children who present with COVID-19 ARDS compared to COVID -19 induced MIS-C. PMID:35501302
2D-DIGE-Based Proteomic Profiling with Validations Identifies Vimentin as a Secretory Biomarker Useful for Early Detection and Poor Prognosis in Oral Cancers. PMID:35498535
iTRAQ-based proteomic analysis reveals several key metabolic pathways associated with male sterility in Salvia miltiorrhiza. PMID:35496921
Identification and Validation of Ferroptosis-Related Biomarkers in Septic Cardiomyopathy via Bioinformatics Analysis. PMID:35495160
Expression, Prognostic Value, and Functional Mechanism of the KDM5 Family in Pancreatic Cancer. PMID:35493099
Wuzi Yanzong pill attenuates MPTP-induced Parkinson's Disease via PI3K/Akt signaling pathway. PMID:35488941
The clinical value of miRNA-21 in cervical cancer: A comprehensive investigation based on microarray datasets. PMID:35486636
Role of Necroptosis and Immune Infiltration in Human Stanford Type A Aortic Dissection: Novel Insights from Bioinformatics Analyses. PMID:35480868
Identification of KIF23 as a Prognostic Biomarker Associated With Progression of Clear Cell Renal Cell Carcinoma. PMID:35478956
An integrated pipeline for mammalian genetic screening. PMID:35474898
Gene-SCOUT: identifying genes with similar continuous trait fingerprints from phenome-wide association analyses. PMID:35474393
Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort. PMID:35474304
Glycation modulates glutamatergic signaling and exacerbates Parkinson's disease-like phenotypes. PMID:35468899
The Reaction Pathway of miR-30c-5p Activates Lipopolysaccharide Promoting the Course of Traumatic and Hemorrhagic Shock Acute Lung Injury. PMID:35463979
Screening of Immune-Related Genes and Predicting the Immunotherapeutic Effects of Formononetin in Breast Cancer: A Bioinformatics Analysis. PMID:35463082
Identification of the potential biological target molecules related to primary open-angle glaucoma. PMID:35461232
Tandem Mass Tagging (TMT) Reveals Tissue-Specific Proteome of L4 Larvae of Anisakis simplex s. s.: Enzymes of Energy and/or Carbohydrate Metabolism as Potential Drug Targets in Anisakiasis. PMID:35457153
Identification of Potential Key Genes in Prostate Cancer with Gene Expression, Pivotal Pathways and Regulatory Networks Analysis Using Integrated Bioinformatics Methods. PMID:35456461
Genomic and Transcriptomic Characterization of Atypical Recurrent Flank Alopecia in the Cesky Fousek. PMID:35456456
Transcriptional Profiling and Deriving a Seven-Gene Signature That Discriminates Active and Latent Tuberculosis: An Integrative Bioinformatics Approach. PMID:35456421
Integrated In Silico Analyses Identify PUF60 and SF3A3 as New Spliceosome-Related Breast Cancer RNA-Binding Proteins. PMID:35453681
Bioinformatic Analysis Reveals Hub Immune-Related Genes of Diabetic Foot Ulcers. PMID:35449555
UBE2D1 and COX7C as Potential Biomarkers of Diabetes-Related Sepsis. PMID:35445133
Identification and Validation of Hub Genes with Poor Prognosis in Hepatocellular Carcinoma by Integrated Bioinformatical Analysis. PMID:35431572
Pericardial fluid proteomic label-free quantification of differentially expressed proteins in ischemic heart disease patients with systolic dysfunction by nano-LC-ESI-MS/MS analysis. PMID:35423047
Pulmonary Inflammatory Response in Lethal COVID-19 Reveals Potential Therapeutic Targets and Drugs in Phases III/IV Clinical Trials. PMID:35422702
Bayesian hierarchical lasso Cox model: A 9-gene prognostic signature for overall survival in gastric cancer in an Asian population. PMID:35421138
Transcriptome analysis of skin color variation during and after overwintering of Malaysian red tilapia. PMID:35419737
ELK3 Controls Gastric Cancer Cell Migration and Invasion by Regulating ECM Remodeling-Related Genes. PMID:35409069
Analysis of the Composition of Deinagkistrodon acutus Snake Venom Based on Proteomics, and Its Antithrombotic Activity and Toxicity Studies. PMID:35408629
Molecular Genetics and Cytotoxic Responses to Titanium Diboride and Zinc Borate Nanoparticles on Cultured Human Primary Alveolar Epithelial Cells. PMID:35407693
Transcriptional CDK Inhibitors as Potential Treatment Option for Testicular Germ Cell Tumors. PMID:35406461
Toxoplasma gondii infection induces cell apoptosis via multiple pathways revealed by transcriptome analysis. PMID:35403386
Identification of core genes associated with type 2 diabetes mellitus and gastric cancer by bioinformatics analysis. PMID:35402578
Integration of Metabolomics and Proteomics in Exploring the Endothelial Dysfunction Mechanism Induced by Serum Exosomes From Diabetic Retinopathy and Diabetic Nephropathy Patients. PMID:35399949
Multi-omics data integration analysis identifies the spliceosome as a key regulator of DNA double-strand break repair. PMID:35399185
Genomic changes underlying repeated niche shifts in an adaptive radiation. PMID:35398888
Quantitative Proteomic Analysis Reveals Important Roles of the Acetylation of ER-Resident Molecular Chaperones for Conidiation in Fusarium oxysporum. PMID:35398590
Identification of microRNA-mRNA-TF regulatory networks in periodontitis by bioinformatics analysis. PMID:35397550
Wheat grain proteomic and protein-metabolite interactions analyses provide insights into plant growth promoting bacteria-arbuscular mycorrhizal fungi-wheat interactions. PMID:35396966
TGF-β induced reprogramming and drug resistance in triple-negative breast cells. PMID:35395809
Identification of Novel Biomarkers With Diagnostic Value and Immune Infiltration in Burn Injury. PMID:35391790
Predicted mouse interactome and network-based interpretation of differentially expressed genes. PMID:35390003
Dynamic Changes in the Proteome of Early Bovine Embryos Developed In Vivo. PMID:35386205
Exploration of Hanshi Zufei prescription for treatment of COVID-19 based on network pharmacology. PMID:35382000
Identification of Key Genes and Pathways in Peripheral Blood Mononuclear Cells of Type 1 Diabetes Mellitus by Integrated Bioinformatics Analysis. PMID:35381625
Proteomic landscape subtype and clinical prognosis of patients with the cognitive impairment by Japanese encephalitis infection. PMID:35379280
Bioinformatical analysis identifies PDLIM3 as a potential biomarker associated with immune infiltration in patients with endometriosis. PMID:35378934
Uncovering the Neuroprotective Effect of Hedysarum multijugum Maxim-Chuanxiong Rhizoma Compound on Cerebral Infarction through Quantitative Proteomics. PMID:35378910
Platinum Chemotherapy Induces Lymphangiogenesis in Cancerous and Healthy Tissues That Can be Prevented With Adjuvant Anti-VEGFR3 Therapy. PMID:35372032
Text Mining-Based Drug Discovery for Connective Tissue Disease-Associated Pulmonary Arterial Hypertension. PMID:35370713
Construction of a Quantitative Genomic Map, Identification and Expression Analysis of Candidate Genes for Agronomic and Disease-Related Traits in Brassica napus. PMID:35360294
Chicken Peripheral Blood Mononuclear Cells Response to Avian Leukosis Virus Subgroup J Infection Assessed by Single-Cell RNA Sequencing. PMID:35359721
Arsenic alters nitric oxide signaling similar to autism spectrum disorder and Alzheimer's disease-associated mutations. PMID:35351881
Comprehensive Genetic Analysis of Tuberculosis and Identification of Candidate Biomarkers. PMID:35345666
Clinical Significance and Potential Mechanisms of ATP Binding Cassette Subfamily C Genes in Hepatocellular Carcinoma. PMID:35342392
Integrated Network Pharmacology and Mice Model to Investigate Qing Zao Fang for Treating Sjögren's Syndrome. PMID:35341135
The Analyses of Cetacean Virus-Responsive Genes Reveal Evolutionary Marks in Mucosal Immunity-Associated Genes. PMID:35334059
Context dependent isoform specific PI3K inhibition confers drug resistance in hepatocellular carcinoma cells. PMID:35331184
Study of Dimorphism Transition Mechanism of Tremella fuciformis Based on Comparative Proteomics. PMID:35330244
Identification of Potential Genes Encoding Protein Transporters in Arabidopsis thaliana Glucosinolate (GSL) Metabolism. PMID:35330077
Screening the Significant Hub Genes by Comparing Tumor Cells, Normoxic and Hypoxic Glioblastoma Stem-like Cell Lines Using Co-Expression Analysis in Glioblastoma. PMID:35328072
Detection of copy number variants and genes by chromosomal microarray in an Emirati neurodevelopmental disorders cohort. PMID:35325322
Evaluation of the TRIP13 level in breast cancer and insights into potential molecular pathways. PMID:35322916
Outstanding prognostic value of novel ferroptosis-related genes in chemoresistance osteosarcoma patients. PMID:35322804
Endoplasmic reticulum chaperone genes encode effectors of long-term memory. PMID:35319980
Identification of differentially expressed genes and signaling pathways with Candida infection by bioinformatics analysis. PMID:35314002
Profiling and functional analysis of differentially expressed circular RNAs identified in foot-and-mouth disease virus infected PK-15 cells. PMID:35313983
Transcriptome Analysis of Bovine Rumen Tissue in Three Developmental Stages. PMID:35309117
Multiomics to elucidate inflammatory bowel disease risk factors and pathways. PMID:35301463
A general calculus of fitness landscapes finds genes under selection in cancers. PMID:35301263
Expression characterization and cross-species complementation uncover the functional conservation of YABBY genes for leaf abaxial polarity and carpel polarity establishment in Saccharum spontaneum. PMID:35300591
BTG2 Serves as a Potential Prognostic Marker and Correlates with Immune Infiltration in Lung Adenocarcinoma. PMID:35300128
Identification of Down-Regulated ADH1C is Associated With Poor Prognosis in Colorectal Cancer Using Bioinformatics Analysis. PMID:35300114
Epilepsy Combined With Multiple Gene Heterozygous Mutation. PMID:35299674
Broiler chickens with 1950s genetics display a stable immune profile as measured by Kinome, mRNA expression, and metabolism when stimulated early in life with CpG. PMID:35299064
Creeping yeast: a simple, cheap and robust protocol for the identification of mating type in Saccharomyces cerevisiae. PMID:35298616
The Key Genes Underlying Pathophysiology Correlation Between the Acute Myocardial Infarction and COVID-19. PMID:35282650
Identification of solute carrier family genes related to the prognosis and tumor-infiltrating immune cells of pancreatic ductal adenocarcinoma. PMID:35282128
Proteomic analysis of descending thoracic aorta identifies unique and universal signatures of aneurysm and dissection. PMID:35280433
Integrated analysis of differentially expressed genes and a ceRNA network to identify hub lncRNAs and potential drugs for multiple sclerosis. PMID:35273684
Identification of Candidate lncRNA and Pseudogene Biomarkers Associated with Carbon-Nanotube-Induced Malignant Transformation of Lung Cells and Prediction of Potential Preventive Drugs. PMID:35270630
Comprehensive Transcriptome Profiling of NAFLD- and NASH-Induced Skeletal Muscle Dysfunction. PMID:35265044
Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions. PMID:35259090
Comparative genomics analysis of statistically significant genomic islands of Helicobacter pylori strains for better understanding the disease prognosis. PMID:35258077
The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome. PMID:35255833
Proteome-wide cellular thermal shift assay reveals unexpected cross-talk between brassinosteroid and auxin signaling. PMID:35254915
Identifying Potential Biomarkers of Prognostic Value in Colorectal Cancer via Tumor Microenvironment Data Mining. PMID:35251116
Plasma proteome changes linked to late phase response after inhaled allergen challenge in asthmatics. PMID:35248034
Label-free quantitative proteomics of maize roots from different root zones provides insight into proteins associated with enhance water uptake. PMID:35247985
Identification of gene biomarkers with expression profiles in patients with allergic rhinitis. PMID:35246242
Identification of novel therapeutic targets for Fuchs' endothelial corneal dystrophy based on gene bioinformatics analysis. PMID:35239706
Downregulation of Three Immune-Specific Core Genes and the Regulatory Pathways in Children and Adult Friedreich's Ataxia: A Comprehensive Analysis Based on Microarray. PMID:35237223
Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer's disease: review, recommendation, implementation and application. PMID:35236372
Predicting Diagnostic Gene Biomarkers Associated With Immune Checkpoints, N6-Methyladenosine, and Ferroptosis in Patients With Acute Myocardial Infarction. PMID:35224064
The Effects and Underlying Mechanisms of Hepatitis B Virus X Gene Mutants on the Development of Hepatocellular Carcinoma. PMID:35223517
Characterization and Interaction Analysis of the Secondary Cell Wall Synthesis-Related Transcription Factor PmMYB7 in Pinus massoniana Lamb. PMID:35216196
Meta-Analysis of Common and Differential Transcriptomic Responses to Biotic and Abiotic Stresses in Arabidopsis thaliana. PMID:35214836
Mapping the gene network landscape of Alzheimer's disease through integrating genomics and transcriptomics. PMID:35213535
CMTR1 is recruited to transcription start sites and promotes ribosomal protein and histone gene expression in embryonic stem cells. PMID:35212377
Integrative Analysis of the lncRNA-Associated ceRNA Regulatory Network Response to Hypoxia in Alveolar Type II Epithelial Cells of Tibetan Pigs. PMID:35211545
Integrated Proteomics Based on 2D Gel Electrophoresis and Mass Spectrometry with Validations: Identification of a Biomarker Compendium for Oral Submucous Fibrosis-An Indian Study. PMID:35207696
Circulating Proteins Associated with Response and Resistance to Neoadjuvant Chemotherapy in HER2-Positive Breast Cancer. PMID:35205837
Identification of Key Proteins from the Alternative Lengthening of Telomeres-Associated Promyelocytic Leukemia Nuclear Bodies Pathway. PMID:35205052
Exploiting Interdata Relationships in Prostate Cancer Proteomes: Clinical Significance of HO-1 Interactors. PMID:35204174
Identification of Potential Immune Checkpoint Inhibitor Targets in Gliomas via Bioinformatic Analyses. PMID:35198632
Mechanisms of Vitamin C Regulating Immune and Inflammation Associated with Neonatal Hypoxic-Ischemic Encephalopathy Based on Network Pharmacology and Molecular Simulation Technology. PMID:35198034
Transcriptome Analysis of Peripheral Blood Mononuclear Cells in SARS-CoV-2 Naïve and Recovered Individuals Vaccinated With Inactivated Vaccine. PMID:35186784
A Prognostic Model for Acute Myeloid Leukemia Based on IL-2/STAT5 Pathway-Related Genes. PMID:35186733
Identification, Molecular Characteristics, and Evolution of GRF Gene Family in Foxtail Millet (Setaria italica L.). PMID:35185998
Gene expression profiling reveals candidate biomarkers and probable molecular mechanisms in chronic stress. PMID:35184642
Proteomic analysis reveals rattlesnake venom modulation of proteins associated with cardiac tissue damage in mouse hearts. PMID:35182786
Aldehyde Dehydrogenase 2 Family Member (ALDH2) Is a Therapeutic Index for Oxaliplatin Response on Colorectal Cancer Therapy with Dysfunction p53. PMID:35178443
BIRC5 promotes cancer progression and predicts prognosis in laryngeal squamous cell carcinoma. PMID:35178302
Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity. PMID:35178190
Serum Pharmacochemistry Combining Network Pharmacology to Discover the Active Constituents and Effect of Xijiao Dihuang Tang Prescription for Treatment of Blood-Heat and Blood-Stasis Syndrome-Related Disease. PMID:35178159
A Phagosomally Expressed Gene, rv0428c, of Mycobacterium tuberculosis Demonstrates Acetyl Transferase Activity and Plays a Protective Role Under Stress Conditions. PMID:35175508
Proximity proteomics of C9orf72 dipeptide repeat proteins identifies molecular chaperones as modifiers of poly-GA aggregation. PMID:35164882
Deoxycholic Acid Modulates Cell-Junction Gene Expression and Increases Intestinal Barrier Dysfunction. PMID:35163990
Transcriptomics and Functional Analysis of Copper Stress Response in the Sulfate-Reducing Bacterium Desulfovibrio alaskensis G20. PMID:35163324
In Silico Studies of Phytoconstituents from Piper longum and Ocimum sanctum as ACE2 and TMRSS2 Inhibitors: Strategies to Combat COVID-19. PMID:35157239
Identification of Novel Lung Cancer Driver Genes Connecting Different Omics Levels With a Heat Diffusion Algorithm. PMID:35155435
Identification of tumor microenvironment-based genes associated with acquired resistance to EGFR Tyrosine Kinase Inhibitor in Lung Adenocarcinoma. PMID:35154456
Immunogenomic Landscape in Breast Cancer Reveals Immunotherapeutically Relevant Gene Signatures. PMID:35154121
Machine Learning Revealed Ferroptosis Features and a Novel Ferroptosis-Based Classification for Diagnosis in Acute Myocardial Infarction. PMID:35145551
Network Pharmacology- and Molecular Docking-Based Identification of Potential Phytocompounds from Argyreia capitiformis in the Treatment of Inflammation. PMID:35140801
Network inference with Granger causality ensembles on single-cell transcriptomics. PMID:35139376
Secreted protein markers in oral squamous cell carcinoma (OSCC). PMID:35130834
Common genetic aspects between COVID-19 and sarcoidosis: A network-based approach using gene expression data. PMID:35128085
Comprehensive Analyses of Glucose Metabolism in Glioma Reveal the Glioma-Promoting Effect of GALM. PMID:35127693
Identification of Key Genes and Pathways Involved in Circulating Tumor Cells in Colorectal Cancer. PMID:35127345
Therapeutic Targets of Bufalin on Renal Carcinoma and Mechanisms: Experimental Validation of Network Pharmacology Analysis. PMID:35126601
Identification of key biomarkers and potential signaling pathway associated with poor progression of gastric cancer. PMID:35117911
Identification of biomarkers in colon cancer based on bioinformatic analysis. PMID:35117850
Identification of significant genes in non-small cell lung cancer by bioinformatics analyses. PMID:35117799
Key genes involved in cell cycle arrest and DNA damage repair identified in anaplastic thyroid carcinoma using integrated bioinformatics analysis. PMID:35117787
CXCL8 is a potential biomarker for predicting disease progression in gastric carcinoma. PMID:35117450
Identification of adriamycin resistance genes in breast cancer based on microarray data analysis. PMID:35117349
Identification of potential microRNAs in glioblastoma using bioinformatic analysis and prognostic evaluation. PMID:35117343
The expression and prognostic value of RNA binding proteins in clear cell renal cell carcinoma. PMID:35117342
Identification of key candidate genes associated with prognosis of lung adenocarcinoma by integrated bioinformatical analysis. PMID:35117293
Screening of potential genes and transcription factors involved in post-radiation cognitive dysfunction in mice via bioinformatics. PMID:35117246
Competitive endogenous RNA network identifies four long non-coding RNA signature as a candidate prognostic biomarker for lung adenocarcinoma. PMID:35116848
Knockdown of RPL34 suppresses osteosarcoma cell proliferation likely through EIF3/FAU signaling pathway. PMID:35116824
Systematically integrative analysis identifies diagnostic and prognostic candidates and small-molecule drugs for lung adenocarcinoma. PMID:35116665
Integrated bioinformatics analysis to identify key genes related to the prognosis of esophageal squamous cell carcinoma. PMID:35116493
ADRB2 is a potential protective gene in breast cancer by regulating tumor immune microenvironment. PMID:35116377
Identification of six hub genes and analysis of their correlation with drug sensitivity in acute myeloid leukemia through bioinformatics. PMID:35116245
Selected by bioinformatics and molecular docking analysis, Dhea and 2-14,15-Eg are effective against cholangiocarcinoma. PMID:35113866
RNA-seq of nine canine prostate cancer cell lines reveals diverse therapeutic target signatures. PMID:35109825
Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning. PMID:35106125
Analysis of the effect of NEKs on the prognosis of patients with non-small-cell lung carcinoma based on bioinformatics. PMID:35105934
Overexpression of SKA Complex Is Associated With Poor Prognosis in Gliomas. PMID:35095717
Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity. PMID:35087228
Sparse dictionary learning recovers pleiotropy from human cell fitness screens. PMID:35085500
Role of Hub Genes in the Occurrence and Development of Testicular Cancer Based on Bioinformatics. PMID:35082515
Kidney organoids recapitulate human basement membrane assembly in health and disease. PMID:35076391
Genes regulated by DNA methylation are involved in distinct phenotypes during melanoma progression and are prognostic factors for patients. PMID:35075772
Identification of key regulators in Sarcoidosis through multidimensional systems biological approach. PMID:35075176
Identification of a Glycosyltransferase Signature for Predicting Prognosis and Immune Microenvironment in Neuroblastoma. PMID:35071226
Identifying a hypoxia related score to predict the prognosis of bladder cancer: a study with The Cancer Genome Atlas (TCGA) database. PMID:35070817
Proteomics Analysis of Exosomes From Patients With Active Tuberculosis Reveals Infection Profiles and Potential Biomarkers. PMID:35069505
Prognostic Value and Immune Infiltration Analysis of Nuclear Factor Erythroid-2 Family Members in Ovarian Cancer. PMID:35059466
Identification of Core Genes and Pathways in Melanoma Metastasis via Bioinformatics Analysis. PMID:35054979
Insights into the Host-Pathogen Interaction Pathways through RNA-Seq Analysis of Lens culinaris Medik. in Response to Rhizoctonia bataticola Infection. PMID:35052429
A Dynamic and Combinatorial Histone Code Drives Malaria Parasite Asexual and Sexual Development. PMID:35051657
Study on diverse pathological characteristics of heart failure in different stages based on proteomics. PMID:35048506
Proteomic analysis of inhibitor of apoptosis protein‑like protein‑2 on breast cancer cell proliferation. PMID:35039877
Novel protein kinase C phosphorylated kinase inhibitor-matrine suppresses replication of hepatitis B virus via modulating the mitogen-activated protein kinase signal. PMID:35037840
Identification of potential immunotherapy biomarkers for breast cancer by bioinformatics analysis. PMID:35037689
Comprehensive evaluation of computational methods for predicting cancer driver genes. PMID:35037014
Key genes associated with prognosis and metastasis of clear cell renal cell carcinoma. PMID:35036081
Exploiting protein family and protein network data to identify novel drug targets for bladder cancer. PMID:35035776
Roles, molecular mechanisms, and signaling pathways of TMEMs in neurological diseases. PMID:35035675
Discovery of Therapeutic Candidates for Diabetic Retinopathy Based on Molecular Switch Analysis: Application of a Systematic Process. PMID:35035658
Exploring the Mechanism of Edaravone for Oxidative Stress in Rats with Cerebral Infarction Based on Quantitative Proteomics Technology. PMID:35027937
Identification of Differentially Expressed Genes and Pathways in Human Atrial Fibrillation by Bioinformatics Analysis. PMID:35023949
SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia. PMID:35021089
Analysis of the cells isolated from epithelial cell rests of Malassez through single-cell limiting dilution. PMID:35013397
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease. PMID:35013160
Anticancer Activities of 9-chloro-6-(piperazin-1-yl)-11H-indeno[1,2-c] quinolin-11-one (SJ10) in Glioblastoma Multiforme (GBM) Chemoradioresistant Cell Cycle-Related Oncogenic Signatures. PMID:35008426
Treatment of microglia with Anti-PrP monoclonal antibodies induces neuronal apoptosis in vitro. PMID:35005289
Comparative Proteomic Profiling Identifies Reciprocal Expression of Mitochondrial Proteins Between White and Gray Matter Lesions From Multiple Sclerosis Brains. PMID:35002930
Evaluation of animal model congruence to human depression based on large-scale gene expression patterns of the CNS. PMID:34997033
Identification of Candidate Gene Signatures and Regulatory Networks in Endometriosis and its Related Infertility by Integrated Analysis. PMID:34993929
Systematic analysis of the role of SLC52A2 in multiple human cancers. PMID:34991609
Protein complexes detection based on node local properties and gene expression in PPI weighted networks. PMID:34991441
Role of Calcium Signaling Pathway-Related Gene Regulatory Networks in Ischemic Stroke Based on Multiple WGCNA and Single-Cell Analysis. PMID:34987704
Variations in TAP1 and PSMB9 Genes Involved in Antigen Processing and Presentation Increase the Risk of Vitiligo in the Saudi Community. PMID:34984025
Immunological and prognostic significance of novel ferroptosis-related genes in soft tissue sarcoma. PMID:34982796
Systems Biology and Bioinformatics approach to Identify blood based signatures molecules and drug targets of patient with COVID-19. PMID:34981034
Differential mRNA and long noncoding RNA expression profiles in pediatric B-cell acute lymphoblastic leukemia patients. PMID:34980027
Analysis of Microarray Data from Medulloblastoma Tissue Samples. PMID:34978688
Novel Insights Into Gene Signatures and Their Correlation With Immune Infiltration of Peripheral Blood Mononuclear Cells in Behcet's Disease. PMID:34975900
Regionally Distinct Immune and Metabolic Transcriptional Responses in the Bovine Small Intestine and Draining Lymph Nodes During a Subclinical Mycobacterium avium subsp. paratuberculosis Infection. PMID:34975852
RIGI, TLR7, and TLR3 Genes Were Predicted to Have Immune Response Against Avian Influenza in Indigenous Ducks. PMID:34970593
Extracellular Vesicles Induce an Aggressive Phenotype in Luminal Breast Cancer Cells Via PKM2 Phosphorylation. PMID:34966685
Absorbance or organization into ankylosis: a microarray analysis of haemarthrosis in a sheep model of temporomandibular joint trauma. PMID:34961493
Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells. PMID:34953085
Substrate stiffness regulates the differentiation profile and functions of osteoclasts via cytoskeletal arrangement. PMID:34953003
Multi-omics of the expression and clinical outcomes of TMPRSS2 in human various cancers: A potential therapeutic target for COVID-19. PMID:34951103
SIRT5 Directly Inhibits the PI3K/AKT Pathway in Prostate Cancer Cell Lines. PMID:34949659
Multi-Omics Reveal the Immunological Role and the Theragnostic Value of miR-216a/GDF15 Axis in Human Colon Adenocarcinoma. PMID:34948431
Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications for Pathogenic Mechanism and Drug Targeting. PMID:34946847
Exploring the Potential Targets and Mechanisms of Huang Lian Jie Du Decoction in the Treatment of Coronavirus Disease 2019 Based on Network Pharmacology. PMID:34938107
Gene set analysis with graph embedded kernel association test. PMID:34935928
Bioinformatics and in-silico findings reveal medical features and pharmacological targets of biochanin A against colorectal cancer and COVID-19. PMID:34931923
[Formula: see text]: ComplexOme-Structural Network Interpreter used to study spatial enrichment in metazoan ribosomes. PMID:34930116
Effects of Serum Metabolites on the Pancreatic Transcriptome in Acute Acalculous Cholecystitis. PMID:34925503
Identification of Hub Genes Associated With Tuberculous Pleurisy by Integrated Bioinformatics Analysis. PMID:34925441
Network Pharmacology and Experimental Assessment to Explore the Pharmacological Mechanism of Qimai Feiluoping Decoction Against Pulmonary Fibrosis. PMID:34925028
BrCNGC gene family in field mustard: genome-wide identification, characterization, comparative synteny, evolution and expression profiling. PMID:34921218
NFAT as a Biomarker and Therapeutic Target in Non-Small Cell Lung Cancer-Related Brain Metastasis. PMID:34917508
Identification of a Lipid Metabolism-Associated Gene Signature Predicting Survival in Breast Cancer. PMID:34916832
Use of a Network-Based Method to Identify Latent Genes Associated with Hearing Loss in Children. PMID:34912812
Protein-protein interactions: Methods, databases, and applications in virus-host study. PMID:34909403
A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease. PMID:34906219
Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis. PMID:34904718
Cystic Fibrosis: Systems Biology Analysis from Homozygous p.Phe508del Variant Patients' Samples Reveals Perturbations in Tissue-Specific Pathways. PMID:34901273
A Random Walk-Based Method to Identify Candidate Genes Associated With Lymphoma. PMID:34899868
Transcriptional Profiling of Early and Late Phases of Bovine Tuberculosis. PMID:34898250
Identification of novel biomarkers in breast cancer via integrated bioinformatics analysis and experimental validation. PMID:34895070
Analysis of a circRNA-, miRNA-, and mRNA-associated ceRNA network reveals potential biomarkers in preeclampsia a ceRNA network in preeclampsia. PMID:34894939
Investigation of Antidepressant Properties of Yohimbine by Employing Structure-Based Computational Assessments. PMID:34889886
Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy. PMID:34884921
Transcriptomics Changes in the Peritoneum of Mice with Lipopolysaccharide-Induced Peritonitis. PMID:34884814
Phosphocatalytic Kinome Activity Profiling of Apoptotic and Ferroptotic Agents in Multiple Myeloma Cells. PMID:34884535
The Hydrogen-Coupled Oligopeptide Membrane Cotransporter Pept2 is SUMOylated in Kidney Distal Convoluted Tubule Cells. PMID:34881291
Quantitative proteomic screen identifies annexin A2 as a host target for Salmonella pathogenicity island-2 effectors SopD2 and PipB2. PMID:34880286
Transcription factor network analysis based on single cell RNA-seq identifies that Trichostatin-a reverses docetaxel resistance in prostate Cancer. PMID:34879849
Plasma-derived candidate biomarkers for detection of gallbladder carcinoma. PMID:34876625
ACSL4 Expression Is Associated With CD8+ T Cell Infiltration and Immune Response in Bladder Cancer. PMID:34868963
Integrated Analysis of Hub Genes and MicroRNAs in Human Placental Tissues from In Vitro Fertilization-Embryo Transfer. PMID:34867824
PI4-kinase and PfCDPK7 signaling regulate phospholipid biosynthesis in Plasmodium falciparum. PMID:34866326
Prognostic value of immune-related genes and comparative analysis of immune cell infiltration in lung adenocarcinoma: sex differences. PMID:34863300
Reserpine improves Enterobacteriaceae resistance in chicken intestine via neuro-immunometabolic signaling and MEK1/2 activation. PMID:34862463
Urinary Exosomal miRNAs as biomarkers of bladder Cancer and experimental verification of mechanism of miR-93-5p in bladder Cancer. PMID:34861847
The chromosome-level genome provides insight into the molecular mechanism underlying the tortuous-branch phenotype of Prunus mume. PMID:34861048
Potential Mechanism of Dingji Fumai Decoction Against Atrial Fibrillation Based on Network Pharmacology, Molecular Docking, and Experimental Verification Integration Strategy. PMID:34859062
In Vitro Folliculogenesis in Mammalian Models: A Computational Biology Study. PMID:34859047
The Transcriptional Differences of Avian CD4+CD8+ Double-Positive T Cells and CD8+ T Cells From Peripheral Blood of ALV-J Infected Chickens Revealed by Smart-Seq2. PMID:34858872
Topical Application of Temperature-Sensitive Gel Containing Caerin 1.1 and 1.9 Peptides on TC-1 Tumour-Bearing Mice Induced High-Level Immune Response in the Tumour Microenvironment. PMID:34858827
Identifying the Effect of Ursolic Acid Against Triple-Negative Breast Cancer: Coupling Network Pharmacology With Experiments Verification. PMID:34858165
Identification of proteins associated with bast fiber growth of ramie by differential proteomic analysis. PMID:34856929
Identification of prognostic genes in the pancreatic adenocarcinoma immune microenvironment by integrated bioinformatics analysis. PMID:34854950
Identification of key pathways and RNAs associated with skeletal muscle atrophy after spinal cord injury. PMID:34854395
Identification of circRNA-miRNA-mRNA Regulatory Network and Autophagy Interaction Network in Atrial Fibrillation Based on Bioinformatics Analysis. PMID:34848999
Epididymal mRNA and miRNA transcriptome analyses reveal important genes and miRNAs related to sperm motility in roosters. PMID:34844112
A multitask transfer learning framework for the prediction of virus-human protein-protein interactions. PMID:34837942
Transcriptional analysis and target genes discovery of Pseudomonas aeruginosa biofilm developed ex vivo chronic wound model. PMID:34837552
Effects of Lingonberry (Vaccinium vitis-idaea L.) Supplementation on Hepatic Gene Expression in High-Fat Diet Fed Mice. PMID:34835949
Alkyne-Tagged Apigenin, a Chemical Tool to Navigate Potential Targets of Flavonoid Anti-Dengue Leads. PMID:34834059
The Rpd3-Complex Regulates Expression of Multiple Cell Surface Recycling Factors in Yeast. PMID:34830359
Phosphoproteomic Comparison of Four Eimeria tenella Life Cycle Stages. PMID:34829991
Genomewide Association Analyses of Lactation Persistency and Milk Production Traits in Holstein Cattle Based on Imputed Whole-Genome Sequence Data. PMID:34828436
Leaf Size Development Differences and Comparative Trancriptome Analyses of Two Poplar Genotypes. PMID:34828380
Identification of miRNA-mRNA network and immune-related gene signatures in IgA nephropathy by integrated bioinformatics analysis. PMID:34823491
A ubiquitous disordered protein interaction module orchestrates transcription elongation. PMID:34822292
Identification of ITPR1 as a Hub Gene of Group 3 Medulloblastoma and Coregulated Genes with Potential Prognostic Values. PMID:34822110
Arecoline Enhances Phosphodiesterase 4A Activity to Promote Transforming Growth Factor-β-Induced Buccal Mucosal Fibroblast Activation via cAMP-Epac1 Signaling Pathway. PMID:34819854
Transcriptome dynamics in developing testes of domestic cats and impact of age on tissue resilience to cryopreservation. PMID:34814833
Analysis and Construction of a Molecular Diagnosis Model of Drug-Resistant Epilepsy Based on Bioinformatics. PMID:34805265
Genome-Wide Analyses of Proteome and Acetylome in Zymomonas mobilis Under N2-Fixing Condition. PMID:34803957
Exploring the mechanism of Yixinyin for myocardial infarction by weighted co-expression network and molecular docking. PMID:34799616
Spatial transcriptomics reveals gene expression characteristics in invasive micropapillary carcinoma of the breast. PMID:34799559
Dynamic Protein Corona of Gold Nanoparticles with an Evolving Morphology. PMID:34797630
Bioinformatics analyses of the pathogenesis and new biomarkers of chronic obstructive pulmonary disease. PMID:34797299
CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity. PMID:34795452
Genome-wide identification and expression analysis of sucrose nonfermenting-1-related protein kinase (SnRK) genes in Triticum aestivum in response to abiotic stress. PMID:34795369
Circular RNA-associated ceRNA network involved in HIF-1 signalling in triple-negative breast cancer: circ_0047303 as a potential key regulator. PMID:34791795
The phenotypic characteristics of patients with athelia and tooth agenesis. PMID:34790789
TCGA database analysis of the tumor mutation burden and its clinical significance in colon cancer. PMID:34790389
Clinical values and potential pathways of miR-183-5p in gastric cancer: a study based on integrational bioinformatics analysis. PMID:34790379
MicroRNA-146a Serves as a Biomarker for Adverse Prognosis of ST-Segment Elevation Myocardial Infarction. PMID:34786024
Prognostic Significance of Alternative Splicing Genes in Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma. PMID:34785939
Network based analysis identifies TP53m-BRCA1/2wt-homologous recombination proficient (HRP) population with enhanced susceptibility to Vigil immunotherapy. PMID:34785763
Mapping cis-regulatory elements in the midgestation mouse placenta. PMID:34785717
Aryl hydrocarbon receptor is a prognostic biomarker and is correlated with immune responses in cervical cancer. PMID:34784845
Modeling of endothelial cell dysfunction using human induced pluripotent stem cells derived from patients with end-stage renal disease. PMID:34781643
EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma. PMID:34772733
Multi-Omics Analysis of Glioblastoma Cells' Sensitivity to Oncolytic Viruses. PMID:34771433
Potential Muscle-Related Biomarkers in Predicting Curve Progression to the Surgical Threshold in Adolescent Idiopathic Scoliosis-A Pilot Proteomic Study Comparing Four Non-Progressive vs. Four Progressive Patients vs. A Control Cohort. PMID:34768447
Optimizing network propagation for multi-omics data integration. PMID:34762640
Functional drug-target-disease network analysis of gene-phenotype connectivity for curcumin in hepatocellular carcinoma. PMID:34754622
3-D vascularized breast cancer model to study the role of osteoblast in formation of a pre-metastatic niche. PMID:34754042
The Novel Tumor Microenvironment-Related Prognostic Gene AIF1 May Influence Immune Infiltrates and is Correlated with TIGIT in Esophageal Cancer. PMID:34751872
JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics. PMID:34747401
Exploring the Molecular Mechanism of Action of Yinchen Wuling Powder for the Treatment of Hyperlipidemia, Using Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation. PMID:34746316
Aberrant Methylation and Immune Microenvironment Are Associated With Overexpressed Fibronectin 1: A Diagnostic and Prognostic Target in Head and Neck Squamous Cell Carcinoma. PMID:34746236
Identification of Gene-Set Signature in Early-Stage Hepatocellular Carcinoma and Relevant Immune Characteristics. PMID:34745960
The Significance of SIX1 as a Prognostic Biomarker for Survival Outcome in Various Cancer Patients: A Systematic Review and Meta-Analysis. PMID:34745930
MiR-16-5p suppresses breast cancer proliferation by targeting ANLN. PMID:34743685
Potentiating antibiotic efficacy via perturbation of non-essential gene expression. PMID:34741116
Integrated Transcriptomic Analysis Revealed Hub Genes and Pathways Involved in Sorafenib Resistance in Hepatocellular Carcinoma. PMID:34737677
Model constructions of chemosensitivity and prognosis of high grade serous ovarian cancer based on evaluation of immune microenvironment and immune response. PMID:34736480
Exploring the Potential Mechanism of Xiaokui Jiedu Decoction for Ulcerative Colitis Based on Network Pharmacology and Molecular Docking. PMID:34733451
Proteins related to ictogenesis and seizure clustering in chronic epilepsy. PMID:34728717
Massive QTL analysis identifies pleiotropic genetic determinants for stress resistance, aroma formation, and ethanol, glycerol and isobutanol production in Saccharomyces cerevisiae. PMID:34727964
Comprehensive Bioinformatics Analysis of Lipopolysaccharide-Induced Altered Autophagy in Acute Lung Injury and Construction of Underlying Competing Endogenous RNA Regulatory Mechanism. PMID:34722769
Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion. PMID:34719887
Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells. PMID:34717622
Genome-wide association study uncovers major genetic loci associated with seed flooding tolerance in soybean. PMID:34715792
NCF1/2/4 Are Prognostic Biomarkers Related to the Immune Infiltration of Kidney Renal Clear Cell Carcinoma. PMID:34708124
Potential value and chemical characterization of gut microbiota derived nitrogen containing metabolites in feces from Periplaneta americana (L.) at different growth stages. PMID:34707100
Hypomethylation and downregulation of miR-23b-3p are associated with upregulated PLAU: a diagnostic and prognostic biomarker in head and neck squamous cell carcinoma. PMID:34702271
Systematic proteomics analysis of lysine acetylation reveals critical features of placental proteins in pregnant women with preeclampsia. PMID:34697885
Bioinformatics screening of biomarkers related to liver cancer. PMID:34696748
Prioritization of Diagnostic and Prognostic Biomarkers for Lupus Nephritis Based on Integrated Bioinformatics Analyses. PMID:34692653
Exploring the Extracellular Vesicle MicroRNA Expression Repertoire in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis Treated with TNF Inhibitors. PMID:34691284
Integrative Systems Biology Analysis Elucidates Mastitis Disease Underlying Functional Modules in Dairy Cattle. PMID:34691146
The Expression Regulatory Network in the Lung Tissue of Tibetan Pigs Provides Insight Into Hypoxia-Sensitive Pathways in High-Altitude Hypoxia. PMID:34691141
Identification S100A9 as a potential biomarker in neuroblastoma. PMID:34689294
Transcriptome and unique cytokine microenvironment of Castleman disease. PMID:34686774
Targeting Asparagine and Serine Metabolism in Germinal Centre-Derived B Cells Non-Hodgkin Lymphomas (B-NHL). PMID:34685569
Entropy-Based Graph Clustering of PPI Networks for Predicting Overlapping Functional Modules of Proteins. PMID:34681995
Mining Fiskeby III and Mandarin (Ottawa) Expression Profiles to Understand Iron Stress Tolerant Responses in Soybean. PMID:34681702
Association and Gene-Gene Interactions Study of Late-Onset Alzheimer's Disease in the Russian Population. PMID:34681041
Cell Wall Proteomics Reveal Phenotypic Adaption of Drug-Resistant Mycobacterium smegmatis to Subinhibitory Rifampicin Exposure. PMID:34676224
Construction and Investigation of Competing Endogenous RNA Networks and Candidate Genes Involved in SARS-CoV-2 Infection. PMID:34675627
Investigation of the Active Ingredients and Mechanism of Hudi Enteric-Coated Capsules in DSS-Induced Ulcerative Colitis Mice Based on Network Pharmacology and Experimental Verification. PMID:34675488
The nomogram based on the 6-lncRNA model can promote the prognosis prediction of patients with breast invasive carcinoma. PMID:34675301
Differences in and verification of genetic alterations in chemotherapy and immunotherapy for metastatic melanoma. PMID:34675134
Hypothetical molecular interconnection between type 2 diabetes and dyslexia. PMID:34674647
Identification of Differential Responses of Goat PBMCs to PPRV Virulence Using a Multi-Omics Approach. PMID:34671358
ALDH2 promotes uterine corpus endometrial carcinoma proliferation and construction of clinical survival prognostic model. PMID:34670872
Bioinformatics Prediction and Analysis of MicroRNAs and Their Targets as Biomarkers for Prostate Cancer: A Preliminary Study. PMID:34665432
Extracellular calcium alters calcium-sensing receptor network integrating intracellular calcium-signaling and related key pathway. PMID:34663830
Gene correlation network analysis to identify regulatory factors in sciatic nerve injury. PMID:34663380
Inhibition of Arginine Methylation Impairs Platelet Function. PMID:34661075
Prognostic Value and Immunological Role of MORF4-Related Gene-Binding Protein in Human Cancers. PMID:34660575
Systems Biology and Chemoinformatics-Based Strategies to Explore the Biological Mechanism of Fugui Wenyang Decoction in Treating Vascular Dementia Rats. PMID:34659639
Bioinformatic and experimental analyses of key biomarkers in pancreatic cancer. PMID:34659505
Phosphoproteome analysis reveals an extensive phosphorylation of proteins associated with bast fiber growth in ramie. PMID:34656094
Multiomic study of skin, peripheral blood, and serum: is serum proteome a reflection of disease process at the end-organ level in systemic sclerosis? PMID:34654463
Identification and Validation of Potential Candidate Genes of Colorectal Cancer in Response to Fusobacterium nucleatum Infection. PMID:34650590
Chronic liquid fructose supplementation does not cause liver tumorigenesis but elicits clear sex differences in the metabolic response in Sprague-Dawley rats. PMID:34650394
Placental Changes in the serotonin transporter (Slc6a4) knockout mouse suggest a role for serotonin in controlling nutrient acquisition. PMID:34649169
Exploring the Mechanism of Resveratrol in Reducing the Soft Tissue Damage of Osteoarthritis Based on Network Pharmacology and Experimental Pharmacology. PMID:34646331
Bioinformatics Analysis Identified miR-584-5p and Key miRNA-mRNA Networks Involved in the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells. PMID:34646313
Abiotic Stress Triggers the Expression of Genes Involved in Protein Storage Vacuole and Exocyst-Mediated Routes. PMID:34638986
miRbiom: Machine-learning on Bayesian causal nets of RBP-miRNA interactions successfully predicts miRNA profiles. PMID:34637468
Phosphorylation of CAP1 regulates lung cancer proliferation, migration, and invasion. PMID:34636991
Quantitative proteomics reveals that dormancy-related proteins mediate the attenuation in mycobacterium strains. PMID:34634997
Identification of potential target genes of non-small cell lung cancer in response to resveratrol treatment by bioinformatics analysis. PMID:34633989
A metabolism-relevant signature as a predictor for prognosis and therapeutic response in pancreatic cancer. PMID:34632851
Efficient and accurate identification of protein complexes from protein-protein interaction networks based on the clustering coefficient. PMID:34630943
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment. PMID:34626214
Macrophages exert homeostatic actions in pregnancy to protect against preterm birth and fetal inflammatory injury. PMID:34622802
Quantitative Proteomic Analysis for High- and Low-Aflatoxin-Yield Aspergillus flavus Strains Isolated From Natural Environments. PMID:34621259
Integrated analysis of patients with KEAP1/NFE2L2/CUL3 mutations in lung adenocarcinomas. PMID:34617407
Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy via FAK/SIRT3/ROS Pathway in Cardiomyocyte. PMID:34616362
Effects of periostin deficiency on kidney aging and lipid metabolism. PMID:34607314
Upregulation of ADAM12 Is Associated With a Poor Survival and Immune Cell Infiltration in Colon Adenocarcinoma. PMID:34604068
The Interactions of Small Proline-Rich Proteins with Late Cornified Envelope Proteins are Involved in the Pathogenesis of Psoriasis. PMID:34594126
Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1. PMID:34589742
Molecular Characteristics, Clinical Implication, and Cancer Immunity Interactions of Pyroptosis-Related Genes in Breast Cancer. PMID:34589498
Integration of functional genomics data to uncover cell type-specific pathways affected in Parkinson's disease. PMID:34581766
Deep learning in cancer diagnosis, prognosis and treatment selection. PMID:34579788
Transcriptomic and Proteomic Analysis of Drought Stress Response in Opium Poppy Plants during the First Week of Germination. PMID:34579414
Detection of Circulating Serum Protein Biomarkers of Non-Muscle Invasive Bladder Cancer after Protein Corona-Silver Nanoparticles Analysis by SWATH-MS. PMID:34578700
The MAPK/ERK Pathway and the Role of DUSP1 in JCPyV Infection of Primary Astrocytes. PMID:34578413
Whole-Genome Profiles of Malay Colorectal Cancer Patients with Intact MMR Proteins. PMID:34573430
Identification and validation of circulating miRNAs as potential new biomarkers for severe liver disease in patients with leptospirosis. PMID:34570814
Comprehensive Analysis of mRNA Expression Profiling and Identification of Potential Diagnostic Biomarkers in Coronary Artery Disease. PMID:34568680
Phylogenetic Comparison and Splicing Analysis of the U1 snRNP-specific Protein U1C in Eukaryotes. PMID:34568424
Transcriptomic and Mutational Analysis Discovering Distinct Molecular Characteristics Among Chinese Thymic Epithelial Tumor Patients. PMID:34568003
Comprehensive analysis of abnormal expression, prognostic value and oncogenic role of the hub gene FN1 in pancreatic ductal adenocarcinoma via bioinformatic analysis and in vitro experiments. PMID:34567847
Integrated Analysis of the Expression Characteristics, Prognostic Value, and Immune Characteristics of PPARG in Breast Cancer. PMID:34567087
Combined Transcriptome and Proteome Analysis of Maize (Zea mays L.) Reveals A Complementary Profile in Response to Phosphate Deficiency. PMID:34563050
HIV-Proteins-Associated CNS Neurotoxicity, Their Mediators, and Alternative Treatments. PMID:34562223
TOP1 modulation during melanoma progression and in adaptative resistance to BRAF and MEK inhibitors. PMID:34560251
A Network Pharmacology and Molecular Docking Strategy to Explore Potential Targets and Mechanisms Underlying the Effect of Curcumin on Osteonecrosis of the Femoral Head in Systemic Lupus Erythematosus. PMID:34557547
Bioinformatics analyses of gene expression profile identify key genes and functional pathways involved in cutaneous lupus erythematosus. PMID:34553293
[Exploring the therapeutic mechanism of quercetin for heart failure based on network pharmacology and molecular docking]. PMID:34549711
Exploring the Pleiotropic Genes and Therapeutic Targets Associated with Heart Failure and Chronic Kidney Disease by Integrating metaCCA and SGLT2 Inhibitors' Target Prediction. PMID:34540994
Citrate Synthase and OGDH as Potential Biomarkers of Atherosclerosis under Chronic Stress. PMID:34539976
Shugosin 2 is a biomarker for pathological grading and survival prediction in patients with gliomas. PMID:34535705
Proteomics of autism and Alzheimer's mouse models reveal common alterations in mTOR signaling pathway. PMID:34535637
Placental gene network modules are associated with maternal stress during pregnancy and infant temperament. PMID:34533879
Identification of Novel Choroidal Neovascularization-Related Genes Using Laplacian Heat Diffusion Algorithm. PMID:34532497
Mechanism of Radix Rhei Et Rhizome Intervention in Cerebral Infarction: A Research Based on Chemoinformatics and Systematic Pharmacology. PMID:34531920
Exploring the mechanism of Danggui Buxue Decoction in regulating atherosclerotic disease network based on integrated pharmacological methods. PMID:34528665
Single-cell RNA sequencing analysis to characterize cells and gene expression landscapes in atrial septal defect. PMID:34514716
Discovery of a novel HDACi structure that inhibits the proliferation of ovarian cancer cells in vivo and in vitro. PMID:34512161
Identification of HIF-1α/VEGFA signaling pathway and transcription factors in Kashin-Beck disease by integrated bioinformatics analysis. PMID:34504569
Exosomes Secreted by Adipose-Derived Stem Cells Following FK506 Stimulation Reduce Autophagy of Macrophages in Spine after Nerve Crush Injury. PMID:34502537
Common Genetic Aberrations Associated with Metabolic Interferences in Human Type-2 Diabetes and Acute Myeloid Leukemia: A Bioinformatics Approach. PMID:34502231
Unraveling the Relevance of ARL GTPases in Cutaneous Melanoma Prognosis through Integrated Bioinformatics Analysis. PMID:34502169
Bioinformatics and Immune Infiltration Analyses Reveal the Key Pathway and Immune Cells in the Pathogenesis of Hypertrophic Cardiomyopathy. PMID:34497835
DeepComplex: A Web Server of Predicting Protein Complex Structures by Deep Learning Inter-chain Contact Prediction and Distance-Based Modelling. PMID:34497831
Gene Expression Analysis Reveals Key Genes and Signalings Associated with the Prognosis of Prostate Cancer. PMID:34497666
MicroRNA-221-3p Suppresses the Microglia Activation and Seizures by Inhibiting of HIF-1α in Valproic Acid-Resistant Epilepsy. PMID:34497517
Regulatory Network of PD1 Signaling Is Associated with Prognosis in Glioblastoma Multiforme. PMID:34493595
Pentosan polysulfate sodium prevents functional decline in chikungunya infected mice by modulating growth factor signalling and lymphocyte activation. PMID:34492036
Global Identification and Systematic Analysis of Lysine Malonylation in Maize (Zea mays L.). PMID:34490025
Defining a Methylation Signature Associated With Operational Tolerance in Kidney Transplant Recipients. PMID:34489960
Integrated analysis of Solute carrier family-2 members reveals SLC2A4 as an independent favorable prognostic biomarker for breast cancer. PMID:34488531
Candidate gene prioritization for chronic obstructive pulmonary disease using expression information in protein-protein interaction networks. PMID:34481483
Serum exosome-derived biomarkers for the early detection of oral squamous cell carcinoma. PMID:34468926
In silico analysis and molecular identification of an anaphase-promoting complex homologue from human pathogen Entamoeba histolytica. PMID:34468883
Integrative overview of IFITMs family based on Bioinformatics analysis. PMID:34466338
The genome of the extremophile Artemia provides insight into strategies to cope with extreme environments. PMID:34465293
Tetrandrine may treat membranous glomerulopathy via P13K/Akt signaling pathway regulation: therapeutic mechanism validation using Heymann nephritis rat model. PMID:34463195
GSK2126458 has the potential to inhibit the proliferation of pancreatic cancer uncovered by bioinformatics analysis and pharmacological experiments. PMID:34461940
Deep Succinylproteomics of Brain Tissues from Intracerebral Hemorrhage with Inhibition of Toll-Like Receptor 4 Signaling. PMID:34460038
TIAMMAt: Leveraging Biodiversity to Revise Protein Domain Models, Evidence from Innate Immunity. PMID:34459919
Comprehensive Analysis of the Systemic Transcriptomic Alternations and Inflammatory Response during the Occurrence and Progress of COVID-19. PMID:34457122
Comprehensive analysis of differentially expressed genes reveals the promotive effects of UBE2T on colorectal cancer cell proliferation. PMID:34457069
New Insights Into Mitochondrial Dysfunction at Disease Susceptibility Loci in the Development of Type 2 Diabetes. PMID:34456865
Condition-Specific Molecular Network Analysis Revealed That Flagellar Proteins Are Involved in Electron Transfer Processes of Shewanella piezotolerans WP3. PMID:34456634
PCA-based unsupervised feature extraction for gene expression analysis of COVID-19 patients. PMID:34456333
Identification of key proteins in the signaling crossroads between wound healing and cancer hallmark phenotypes. PMID:34446793
Transcriptomic Analysis of Long Noncoding RNA and mRNA Expression Profiles in the Amygdala of Rats with Bone Cancer Pain-Depression Comorbidity. PMID:34440578
Molecular Pathways Involved in the Development of Congenital Erythrocytosis. PMID:34440324
Cytokines Induced by Edwardsiella tarda: Profile and Role in Antibacterial Immunity. PMID:34439908
Bothrops Jararaca Snake Venom Modulates Key Cancer-Related Proteins in Breast Tumor Cell Lines. PMID:34437390
Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes. PMID:34433033
Key radioresistance regulation models and marker genes identified by integrated transcriptome analysis in nasopharyngeal carcinoma. PMID:34432380
Predicting functional consequences of mutations using molecular interaction network features. PMID:34432150
A global map of associations between types of protein posttranslational modifications and human genetic diseases. PMID:34430807
Potential Arabidopsis thaliana glucosinolate genes identified from the co-expression modules using graph clustering approach. PMID:34430080
Intratumoral injection of caerin 1.1 and 1.9 peptides increases the efficacy of vaccinated TC-1 tumor-bearing mice with PD-1 blockade by modulating macrophage heterogeneity and the activation of CD8+ T cells in the tumor microenvironment. PMID:34429969
Effects of Siberian fir terpenes extract Abisil on antioxidant activity, autophagy, transcriptome and proteome of human fibroblasts. PMID:34428743
A Comprehensive Genomic Analysis Constructs miRNA-mRNA Interaction Network in Hepatoblastoma. PMID:34422793
CD86 Molecule Might Be a Novel Immune-Related Prognostic Biomarker for Patients With Bladder Cancer by Bioinformatics and Experimental Assays. PMID:34422632
Cullin-5 (CUL5) as a potential prognostic marker in a pan-cancer analysis of human tumors. PMID:34415831
Aberrant expression of PROS1 correlates with human papillary thyroid cancer progression. PMID:34414029
Granzyme A Produced by γ9δ2 T Cells Activates ER Stress Responses and ATP Production, and Protects Against Intracellular Mycobacterial Replication Independent of Enzymatic Activity. PMID:34413857
A convergent molecular network underlying autism and congenital heart disease. PMID:34411509
Protein profiling in the habenula after chronic (-)-menthol exposure in mice. PMID:34407206
Inverse molecular docking reveals a novel function of thymol: Inhibition of fat deposition induced by high-dose glucose in Caenorhabditis elegans. PMID:34401075
Microarray Analysis of Differential Gene Expression Between Traumatic Temporomandibular Joint Fibrous and Bony Ankylosis in a Sheep Model. PMID:34400603
A novel treatment strategy for lapatinib resistance in a subset of HER2-amplified gastric cancer. PMID:34399705
Exploring the Pharmacological Mechanism of Radix Salvia Miltiorrhizae in the Treatment of Radiation Pneumonia by Using Network Pharmacology. PMID:34395252
Exploring the Pharmacological Mechanism of Liuwei Dihuang Decoction for Diabetic Retinopathy: A Systematic Biological Strategy-Based Research. PMID:34394383
EPIGENOMIC FEATURES RELATED TO MICROGLIA ARE ASSOCIATED WITH ATTENUATED EFFECT OF APOE ε4 ON ALZHEIMER'S DISEASE RISK IN HUMANS. PMID:34393677
Machine Learning in Drug Discovery: A Review. PMID:34393317
Employing bioinformatics analysis to identify hub genes and microRNAs involved in colorectal cancer. PMID:34390411
Hyperleptinemia in obese state renders luminal breast cancers refractory to tamoxifen by coordinating a crosstalk between Med1, miR205 and ErbB. PMID:34389732
Potential genes and pathways associated with heterotopic ossification derived from analyses of gene expression profiles. PMID:34389038
Identification of latent biomarkers in connection with progression and prognosis in oral cancer by comprehensive bioinformatics analysis. PMID:34384424
Pathogenic nsSNPs that increase the risks of cancers among the Orang Asli and Malays. PMID:34373545
The effect of experimental lead pollution on DNA methylation in a wild bird population. PMID:34369261
Glycolysis Define Two Prognostic Subgroups of Lung Adenocarcinoma With Different Mutation Characteristics and Immune Infiltration Signatures. PMID:34368114
Multi-Level Analyses of Genome-Wide Association Study to Reveal Significant Risk Genes and Pathways in Neuromyelitis Optica Spectrum Disorder. PMID:34367251
IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced Reprogramming. PMID:34367159
Integrated Bioinformatics and Validation Reveal Potential Biomarkers Associated With Progression of Primary Sjögren's Syndrome. PMID:34367157
XSP10 and SlSAMT, Fusarium wilt disease responsive genes of tomato (Solanum lycopersicum L.) express tissue specifically and interact with each other at cytoplasm in vivo. PMID:34366597
Identification of prognostic immune-related gene signature associated with tumor microenvironment of colorectal cancer. PMID:34364366
Male Infertility Knowledgebase: decoding the genetic and disease landscape. PMID:34363073
Application and Perspectives of MALDI-TOF Mass Spectrometry in Clinical Microbiology Laboratories. PMID:34361974
Effects of Cancer Presence and Therapy on the Platelet Proteome. PMID:34361002
Interactions Networks for Primary Heart Sarcomas. PMID:34359782
Comparative Proteomic Analysis of Young and Adult Bull (Bos taurus) Cryopreserved Semen. PMID:34359141
Characterization of an Ex Vivo Equine Endometrial Tissue Culture Model Using Next-Generation RNA-Sequencing Technology. PMID:34359123
FLAME: A Web Tool for Functional and Literature Enrichment Analysis of Multiple Gene Lists. PMID:34356520
Analyzing Roles of NUSAP1 From Clinical, Molecular Mechanism and Immune Perspectives in Hepatocellular Carcinoma. PMID:34354737
Transcriptomic analysis reveals that mTOR pathway can be modulated in macrophage cells by the presence of cryptococcal cells. PMID:34352067
Quantitative ubiquitylomics reveals the ubiquitination regulation landscape in oral adenoid cystic carcinoma. PMID:34350460
Identification of potential biomarkers in dengue via integrated bioinformatic analysis. PMID:34347790
Spatial transcriptomics analysis of uterine gene expression in enhancer of zeste homolog 2 conditional knockout mice†. PMID:34344022
Oncogene APOL1 promotes proliferation and inhibits apoptosis via activating NOTCH1 signaling pathway in pancreatic cancer. PMID:34341330
Identification of Multiple Hub Genes and Pathways in Hepatocellular Carcinoma: A Bioinformatics Analysis. PMID:34337056
Integrative Bioinformatics Study of Tangeretin Potential Targets for Preventing Metastatic Breast Cancer. PMID:34335799
Exploring the Regulatory Mechanism of Modified Huanglian Maidong Decoction on Type 2 Diabetes Mellitus Biological Network Based on Systematic Pharmacology. PMID:34335798
Expression and prognostic potential of PLEK2 in head and neck squamous cell carcinoma based on bioinformatics analysis. PMID:34331382
Different circulating biomarkers in women and men with paroxysmal atrial fibrillation: results from the AF-RISK and RACE V studies. PMID:34329401
Oleanolic Acid Induces Autophagy and Apoptosis via the AMPK-mTOR Signaling Pathway in Colon Cancer. PMID:34326874
DTI-Voodoo: machine learning over interaction networks and ontology-based background knowledge predicts drug-target interactions. PMID:34320178
Identification of covalent modifications regulating immune signaling complex composition and phenotype. PMID:34318608
Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma. PMID:34316702
DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer. PMID:34311674
Determining the Traditional Chinese Medicine (TCM) Syndrome with the Best Prognosis of HBV-Related HCC and Exploring the Related Mechanism Using Network Pharmacology. PMID:34306165
Biological knowledge-slanted random forest approach for the classification of calcified aortic valve stenosis. PMID:34301292
Insights into the molecular mechanisms of Huangqi decoction on liver fibrosis via computational systems pharmacology approaches. PMID:34301291
Expression of DDX11 and DNM1L at the 12p11 Locus Modulates Systemic Lupus Erythematosus Susceptibility. PMID:34299244
Integration of Transcriptome and Metabolome Reveals the Genes and Metabolites Involved in Bifidobacterium bifidum Biofilm Formation. PMID:34299216
Identification of G-protein signaling modulator 2 as a diagnostic and prognostic biomarker of pancreatic adenocarcinoma: an exploration of its regulatory mechanisms. PMID:34295565
FOSL2 Is Involved in the Regulation of Glycogen Content in Chicken Breast Muscle Tissue. PMID:34295261
Prognostic Values of E2F1/2 Transcriptional Expressions in Chromophobe Renal Cell Carcinoma Patients: Evidence from Bioinformatics Analysis. PMID:34295182
Identification of tumor microenvironment-related prognostic genes in colorectal cancer based on bioinformatic methods. PMID:34294834
Identification of Key Genes and Underlying Mechanisms in Acute Kawasaki Disease Based on Bioinformatics Analysis. PMID:34290221
Tudor staphylococcal nuclease is a docking platform for stress granule components and is essential for SnRK1 activation in Arabidopsis. PMID:34287990
Transcriptomic Analysis Exploring the Molecular Mechanisms of Hanchuan Zupa Granules in Alleviating Asthma in Rat. PMID:34285702
Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer. PMID:34282029
Transcriptome Analysis of Microglia Reveals That the TLR2/IRF7 Signaling Axis Mediates Neuroinflammation After Subarachnoid Hemorrhage. PMID:34276335
Ileal Derived Organoids From Crohn's Disease Patients Show Unique Transcriptomic and Secretomic Signatures. PMID:34271224
Screening and characterization of hypothetical proteins of Plasmodium falciparum as novel vaccine candidates in the fight against malaria using reverse vaccinology. PMID:34269931
TCF11 Has a Potent Tumor-Repressing Effect Than Its Prototypic Nrf1α by Definition of Both Similar Yet Different Regulatory Profiles, With a Striking Disparity From Nrf2. PMID:34268128
Development and Validation of Novel Biomarkers Related to M2 Macrophages Infiltration by Weighted Gene Co-Expression Network Analysis in Prostate Cancer. PMID:34268107
Microarray-based selection of a serum biomarker panel that can discriminate between latent and active pulmonary TB. PMID:34267288
Long noncoding RNA HOTAIR interacts with Y-Box Protein-1 (YBX1) to regulate cell proliferation. PMID:34266873
Development and Validation of a Random Forest Diagnostic Model of Acute Myocardial Infarction Based on Ferroptosis-Related Genes in Circulating Endothelial Cells. PMID:34262953
Integrated multiplex network based approach for hub gene identification in oral cancer. PMID:34258466
Identification of Key Genes Involved in Pancreatic Ductal Adenocarcinoma with Diabetes Mellitus Based on Gene Expression Profiling Analysis. PMID:34257566
Identification of Biomarkers Related to Immune Cell Infiltration in Hepatocellular Carcinoma Using Gene Co-Expression Network. PMID:34257558
The BBX gene family in Moso bamboo (Phyllostachys edulis): identification, characterization and expression profiles. PMID:34256690
scLink: Inferring Sparse Gene Co-expression Networks from Single-cell Expression Data. PMID:34252628
Identification of potential micro-messenger RNAs (miRNA-mRNA) interaction network of osteosarcoma. PMID:34252359
Identification of a three-gene-based prognostic model in multiple myeloma using bioinformatics analysis. PMID:34249481
Trajectories of Homoeolog-Specific Expression in Allotetraploid Tragopogon castellanus Populations of Independent Origins. PMID:34249049
A Continuous Battle for Host-Derived Glycans Between a Mucus Specialist and a Glycan Generalist in vitro and in vivo. PMID:34248864
Exploring the Regulatory Mechanism of Hedysarum Multijugum Maxim.-Chuanxiong Rhizoma Compound on HIF-VEGF Pathway and Cerebral Ischemia-Reperfusion Injury's Biological Network Based on Systematic Pharmacology. PMID:34248611
Bioinformatics analysis of the role of CXC ligands in the microenvironment of head and neck tumor. PMID:34247149
Bioinformatics analysis of differentially expressed genes and identification of an miRNA-mRNA network associated with entorhinal cortex and hippocampus in Alzheimer's disease. PMID:34243818
Databases for Protein-Protein Interactions. PMID:34236665
The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid-liquid phase separation. PMID:34233002
Identification of potential core genes in esophageal carcinoma using bioinformatics analysis. PMID:34232175
Declined expressions of vast mitochondria-related genes represented by CYCS and transcription factor ESRRA in skeletal muscle aging. PMID:34229541
Prognostic signatures associated with high infiltration of Tregs in bone metastatic prostate cancer. PMID:34229299
Computational identification and characterization of antigenic properties of Rv3899c of Mycobacterium tuberculosis and its interaction with human leukocyte antigen (HLA). PMID:34228167
Bioinformatics integrated analysis to investigate candidate biomarkers and associated metabolites in osteosarcoma. PMID:34225733
Reconstructing Draft Genomes Using Genome Resolved Metagenomics Reveal Arsenic Metabolizing Genes and Secondary Metabolites in Fresh Water Lake in Eastern India. PMID:34220198
Matrisome, innervation and oxidative metabolism affected in older compared with younger males with similar physical activity. PMID:34219410
Dysregulated protein phosphorylation: A determining condition in the continuum of brain aging and Alzheimer's disease. PMID:34218486
Applications and analytical tools of cell communication based on ligand-receptor interactions at single cell level. PMID:34217372
Abnormally increased DNA methylation in chorionic tissue might play an important role in development of ectopic pregnancy. PMID:34215268
Is there a relationship between psoriasis and hepatitis C? A meta-analysis and bioinformatics investigation. PMID:34215260
IRF1 as a potential biomarker in Mycobacterium tuberculosis infection. PMID:34213077
Exploring the Mechanism of Berberine Intervention in Ulcerative Colitis from the Perspective of Inflammation and Immunity Based on Systemic Pharmacology. PMID:34211579
Molecular Insights into the Oxygen-Sensing Pathway and Erythropoietin Expression Regulation in Erythropoiesis. PMID:34209205
OmiEmbed: A Unified Multi-Task Deep Learning Framework for Multi-Omics Data. PMID:34207255
Regulatory miRNA-mRNA Networks in Parkinson's Disease. PMID:34204164
Identifying Hypoxia Characteristics to Stratify Prognosis and Assess the Tumor Immune Microenvironment in Renal Cell Carcinoma. PMID:34194463
Comparative transcriptome analysis reveals distinct gene expression profiles in Brachypodium distachyon infected by two fungal pathogens. PMID:34193039
Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition. PMID:34192548
Light-induced changes in the suprachiasmatic nucleus transcriptome regulated by the ERK/MAPK pathway. PMID:34191798
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα. PMID:34189442
Construction and Validation of a Macrophage-Associated Risk Model for Predicting the Prognosis of Osteosarcoma. PMID:34188683
Functions and clinical significance of KLRG1 in the development of lung adenocarcinoma and immunotherapy. PMID:34187403
Identification ACTA2 and KDR as key proteins for prognosis of PD-1/PD-L1 blockade therapy in melanoma. PMID:34179721
Conjugated C-6 hydroxylated bile acids in serum relate to human metabolic health and gut Clostridia species. PMID:34168163
Identification of hub genes in thyroid carcinoma to predict prognosis by integrated bioinformatics analysis. PMID:34167437
The transcription factor RUNX2 fuels YAP1 signaling and gastric cancer tumorigenesis. PMID:34160112
Precision omics data integration and analysis with interoperable ontologies and their application for COVID-19 research. PMID:34159360
Proteomic differences in the hippocampus and cortex of epilepsy brain tissue. PMID:34159317
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells. PMID:34158391
Multiomic analysis of the function of SPOCK1 across cancers: an integrated bioinformatics approach. PMID:34156309
Node Similarity Based Graph Convolution for Link Prediction in Biological Networks. PMID:34152393
Identification of significant genes and therapeutic agents for breast cancer by integrated genomics. PMID:34151730
GABPα and CREB1 Binding to Double Nucleotide Polymorphisms of Their Consensus Motifs and Cooperative Binding to the Composite ETS ⇔ CRE Motif (ACCGGAAGTGACGTCA). PMID:34151054
Low expression of developing brain homeobox 2 (Dbx2) may serve as a biomarker to predict poor prognosis in endometrial cancer. PMID:34150054
Identification of candidate targets for the diagnosis and treatment of atherosclerosis by bioinformatics analysis. PMID:34150004
Integrative proteomic network analyses support depot-specific roles for leucine rich repeat LGI family member 3 in adipose tissues. PMID:34149883
Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes. PMID:34145303
Integrating genome-wide association and transcriptome prediction model identifies novel target genes for osteoporosis. PMID:34142171
Using Tumor-Infiltrating Immune Cells and a ceRNA Network Model to Construct a Prognostic Analysis Model of Thyroid Carcinoma. PMID:34141614
Stress granules inhibit fatty acid oxidation by modulating mitochondrial permeability. PMID:34133922
Potential prognostic markers and significant lncRNA-mRNA co-expression pairs in laryngeal squamous cell carcinoma. PMID:34131588
Identification of novel hub genes associated with gastric cancer using integrated bioinformatics analysis. PMID:34126961
Heterologous expression of cyanobacterial PCS confers augmented arsenic and cadmium stress tolerance and higher artemisinin in Artemisia annua hairy roots. PMID:34122662
Identification of Key Biomarkers and Immune Infiltration in Sciatic Nerve of Diabetic Neuropathy BKS-db/db Mice by Bioinformatics Analysis. PMID:34122109
Mortalin/glucose-regulated protein 75 promotes the cisplatin-resistance of gastric cancer via regulating anti-oxidation/apoptosis and metabolic reprogramming. PMID:34117210
CCDC114, DNAI2 and TOP2A involves in the effects of tibolone treatment on postmenopausal endometrium. PMID:34116668
A blood RNA transcriptome signature for COVID-19. PMID:34116667
Gene Expression Profile of the Human Colorectal Carcinoma LoVo Cells Treated With Sporamin and Thapsigargin. PMID:34113558
New Insights Into Lignification via Network and Multi-Omics Analyses of Arogenate Dehydratase Knock-Out Mutants in Arabidopsis thaliana. PMID:34113365
A novel method to identify gene interaction patterns. PMID:34112093
Hyaluronan-mediated motility receptor expression functions as a prognostic biomarker in uterine carcinosarcoma based on bioinformatics analysis. PMID:34111996
Single-cell RNA sequencing of human femoral head in vivo. PMID:34111027
Gene Cascade Shift and Pathway Enrichment in Rat Kidney Induced by Acarbose Through Comparative Analysis. PMID:34095098
Expression Analysis of Long Non-Coding RNAs Related With FOXM1, GATA3, FOXA1 and ESR1 in Breast Tissues. PMID:34094972
Laryngeal squamous cell carcinoma cell lines show high tolerance for siRNA-mediated CDK1 knockdown. PMID:34094670
Cellular Tropism of SARS-CoV-2 across Human Tissues and Age-related Expression of ACE2 and TMPRSS2 in Immune-inflammatory Stromal Cells. PMID:34094637
The repertoire of ABC proteins in Clostridioides difficile. PMID:34094001
Site-specific glycoproteomic analysis revealing increased core-fucosylation on FOLR1 enhances folate uptake capacity of HCC cells to promote EMT. PMID:34093861
Effects of Salvia miltiorrhiza extract on lung adenocarcinoma. PMID:34093750
Systematic Pharmacology Reveals the Antioxidative Stress and Anti-Inflammatory Mechanisms of Resveratrol Intervention in Myocardial Ischemia-Reperfusion Injury. PMID:34093716
Identification of core gene in obese type 2 diabetes patients using bioinformatics analysis. PMID:34085602
Responses to chemical cross-talk between the Mycobacterium ulcerans toxin, mycolactone, and Staphylococcus aureus. PMID:34083568
Identification of biomarkers, pathways and potential therapeutic target for docetaxel resistant prostate cancer. PMID:34077304
Inhibition of MMP2-PEX by a novel ester of dihydroxy cinnamic and linoleic acid from the seagrass Cymodocea serrulata. PMID:34075089
ALS-linked PFN1 variants exhibit loss and gain of functions in the context of formin-induced actin polymerization. PMID:34074767
Prospecting Biomarkers for Diagnostic and Therapeutic Approaches in Pythiosis. PMID:34071174
Identifying an lncRNA-Related ceRNA Network to Reveal Novel Targets for a Cutaneous Squamous Cell Carcinoma. PMID:34068010
Comprehensive Transcriptome Analysis of Rare Carpinus putoensis Plants under NO2 stress. PMID:34067657
Transcriptional Response in the Digestive Gland of the King Scallop (Pecten maximus) After the Injection of Domoic Acid. PMID:34067146
Computational Design of Novel Allosteric Inhibitors for Plasmodium falciparum DegP. PMID:34066964
Transcriptomic Changes in Mouse Bone Marrow-Derived Macrophages Exposed to Neuropeptide FF. PMID:34065092
High-Throughput Proteomic Profiling of Nipple Aspirate Fluid from Breast Cancer Patients Compared with Non-Cancer Controls: A Step Closer to Clinical Feasibility. PMID:34064148
The Resistance Responses of Potato Plants to Potato Virus Y Are Associated with an Increased Cellular Methionine Content and an Altered SAM:SAH Methylation Index. PMID:34064103
Identification of the PmWEEP locus controlling weeping traits in Prunus mume through an integrated genome-wide association study and quantitative trait locus mapping. PMID:34059642
Identification of the Core MicroRNAs and Potential Molecular Mechanismsin Sarcoidosis Using Bioinformatics Analysis. PMID:34055877
Identification of a Prognostic Signature for Ovarian Cancer Based on the Microenvironment Genes. PMID:34054929
Bioinformatics-based Identification of Key Pathways and Hub Genes of Traumatic Brain Injury in a Rat Model. PMID:34047944
Collateral Sensitivity to β-Lactam Drugs in Drug-Resistant Tuberculosis Is Driven by the Transcriptional Wiring of BlaI Operon Genes. PMID:34047652
In Silico Structural, Functional, and Phylogenetic Analysis of Cytochrome (CYPD) Protein Family. PMID:34046497
Network Pharmacology-Based Systematic Analysis of Molecular Mechanisms of Dingji Fumai Decoction for Ventricular Arrhythmia. PMID:34046076
Gene expression signatures predict response to therapy with growth hormone. PMID:34045667
Cyclin B1 acts as a tumor microenvironment-related cancer promoter and prognostic biomarker in hepatocellular carcinoma. PMID:34044639
Identification of diagnostic genes and vital microRNAs involved in rheumatoid arthritis: based on data mining and experimental verification. PMID:34040897
Exploring the Mechanism of Zhibai Dihuang Decoction in the Treatment of Ureaplasma Urealyticum-Induced Orchitis Based on Integrated Pharmacology. PMID:34040514
An Integrated Analysis of Network Pharmacology, Molecular Docking, and Experiment Validation to Explore the New Candidate Active Component and Mechanism of Cuscutae Semen-Mori Fructus Coupled-Herbs in Treating Oligoasthenozoospermia. PMID:34040346
ADAMTS12 acts as a tumor microenvironment related cancer promoter in gastric cancer. PMID:34040054
Identification of significant genes as prognostic markers and potential tumor suppressors in lung adenocarcinoma via bioinformatical analysis. PMID:34039311
Transcriptome analysis of potential candidate genes and molecular pathways in colitis-associated colorectal cancer of Mkp-1-deficient mice. PMID:34034704
Integrative web-based analysis of omics data for study of drugs against SARS-CoV-2. PMID:34031435
Mediterranean diet enriched in extra-virgin olive oil or nuts modulates circulating exosomal non-coding RNAs. PMID:34027583
Integrated Analysis of Nine Prognostic RNA-Binding Proteins in Soft Tissue Sarcoma. PMID:34026613
Hub biomarkers for the diagnosis and treatment of glioblastoma based on microarray technology. PMID:34018447
Obesogenic Diets Cause Alterations on Proteins and Theirs Post-Translational Modifications in Mouse Brains. PMID:34017182
AUTS2 Regulates RNA Metabolism and Dentate Gyrus Development in Mice. PMID:34013328
Identification of the EMT-Related Genes Signature for Predicting Occurrence and Progression in Thyroid Cancer. PMID:34012269
A method to delineate de novo missense variants across pathways prioritizes genes linked to autism. PMID:34011629
Characterization and comparison of gene-centered human interactomes. PMID:34010955
ITGA2, LAMB3, and LAMC2 may be the potential therapeutic targets in pancreatic ductal adenocarcinoma: an integrated bioinformatics analysis. PMID:34007003
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions. PMID:34006929
TALEN-Based HvMPK3 Knock-Out Attenuates Proteome and Root Hair Phenotypic Responses to flg22 in Barley. PMID:33995462
Identifying the Potential Therapeutic Targets for Atopic Dermatitis Through the Immune Infiltration Analysis and Construction of a ceRNA Network. PMID:33994801
CTNNB1 S37C mutation causing cells proliferation and migration coupled with molecular mechanisms in lung adenocarcinoma. PMID:33987379
Zebrafish Cancer Predisposition Models. PMID:33987182
Systematic in silico Evaluation of Leishmania spp. Proteomes for Drug Discovery. PMID:33987166
Identification and Validation of SNP-Containing Genes With Prognostic Value in Gastric Cancer via Integrated Bioinformatics Analysis. PMID:33987081
Centromere protein N may be a novel malignant prognostic biomarker for hepatocellular carcinoma. PMID:33987018
WGCNA identification of TLR7 as a novel diagnostic biomarker, progression and prognostic indicator, and immunotherapeutic target for stomach adenocarcinoma. PMID:33982398
ProteoMill: Efficient network-based functional analysis portal for proteomics data. PMID:33978717
Widespread displacement of DNA- and RNA-binding factors underlies toxicity of arginine-rich cell-penetrating peptides. PMID:33978236
High expression of TREM2 promotes EMT via the PI3K/AKT pathway in gastric cancer: bioinformatics analysis and experimental verification. PMID:33976737
Proteome and transcriptome analyses of wheat near isogenic lines identifies key proteins and genes of wheat bread quality. PMID:33976249
Deciphering the Efficacy and Mechanisms of Chinese Herbal Medicine for Diabetic Kidney Disease by Integrating Web-Based Biochemical Databases and Real-World Clinical Data: Retrospective Cohort Study. PMID:33973855
Identification of key pathways and genes in carotid atherosclerosis through bioinformatics analysis of RNA-seq data. PMID:33973530
The Immune-Related Gene HCST as a Novel Biomarker for the Diagnosis and Prognosis of Clear Cell Renal Cell Carcinoma. PMID:33968730
Genome-wide identification, characterization and expression analysis of the LIM transcription factor family in quinoa. PMID:33967462
Prognostic value of members of NFAT family for pan-cancer and a prediction model based on NFAT2 in bladder cancer. PMID:33962392
Genome-wide DNA methylation and RNA-seq analyses identify genes and pathways associated with doxorubicin resistance in a canine diffuse large B-cell lymphoma cell line. PMID:33961622
Bioinformatics analysis of laryngeal squamous cell carcinoma: seeking key candidate genes and pathways. PMID:33954053
The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis. PMID:33953175
MicroRNA-363-3p promote the development of acute myeloid leukemia with RUNX1 mutation by targeting SPRYD4 and FNDC3B. PMID:33950983
Integrative Systems Biology Approaches to Identify Potential Biomarkers and Pathways of Cervical Cancer. PMID:33946372
Underpinning the molecular programming attributing heat stress associated thermotolerance in tea (Camellia sinensis (L.) O. Kuntze). PMID:33931616
Isolation and Characterization of Human Colon Adenocarcinoma Stem-Like Cells Based on the Endogenous Expression of the Stem Markers. PMID:33925224
FLYWCH1, a Multi-Functional Zinc Finger Protein Contributes to the DNA Repair Pathway. PMID:33924684
Prolactin-Releasing Peptide Differentially Regulates Gene Transcriptomic Profiles in Mouse Bone Marrow-Derived Macrophages. PMID:33923285
Discovery-Versus Hypothesis-Driven Detection of Protein-Protein Interactions and Complexes. PMID:33923221
RNA-Seq Reveals Function of Bta-miR-149-5p in the Regulation of Bovine Adipocyte Differentiation. PMID:33922274
Biomarkers in Glycogen Storage Diseases: An Update. PMID:33922238
Understanding the Molecular Mechanism of miR-877-3p Could Provide Potential Biomarkers and Therapeutic Targets in Squamous Cell Carcinoma of the Cervix. PMID:33917510
Functional annotations of ESTs of Stevia rebaudiana involved in abiotic stress signaling through computational approach. PMID:33911971
Identification of Molecular Signatures in Mild Intrinsic Atopic Dermatitis by Bioinformatics Analysis. PMID:33911724
Identification of a prognostic long noncoding RNA signature in lung squamous cell carcinoma: a population-based study with a mean follow-up of 3.5 years. PMID:33910626
Knock out of specific maternal vitellogenins in zebrafish (Danio rerio) evokes vital changes in egg proteomic profiles that resemble the phenotype of poor quality eggs. PMID:33910518
Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants. PMID:33909605
Integrative analysis of the gastric cancer long non-coding RNA-associated competing endogenous RNA network. PMID:33907566
Mining immune-related genes with prognostic value in the tumor microenvironment of breast invasive ductal carcinoma. PMID:33907159
Screening differentially expressed proteins of coronary heart disease with congenital cold syndrome based on tandem mass tag (TMT) technology. PMID:33904367
Genome-wide toxicogenomic study of the lanthanides sheds light on the selective toxicity mechanisms associated with critical materials. PMID:33903247
Advantages of using graph databases to explore chromatin conformation capture experiments. PMID:33902433
Tumor microenvironment characterization in cervical cancer identifies prognostic relevant gene signatures. PMID:33901225
Identification of hub genes associated with obesity-induced hepatocellular carcinoma risk based on integrated bioinformatics analysis. PMID:33900477
Immune Subtyping in Latent Tuberculosis. PMID:33897680
Drug repurposing for cancer treatment through global propagation with a greedy algorithm in a multilayer network. PMID:33893730
Anti Human CX3CR1 VHH Molecule Attenuates Venous Neointimal Hyperplasia of Arteriovenous Fistula in Mouse Model. PMID:33893223
Development of a prognostic index and screening of prognosis related genes based on an immunogenomic landscape analysis of bladder cancer. PMID:33888644
SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2. PMID:33888607
Gene coexpression networks reveal molecular interactions underlying cichlid jaw modularity. PMID:33888061
Expression Profiles Reveal Involvement of VEGF, IGF1, BIRC5, and MMP1 in Vulvar Carcinogenesis. PMID:33888009
In Silico Analysis of High-Risk Missense Variants in Human ACE2 Gene and Susceptibility to SARS-CoV-2 Infection. PMID:33884270
Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer. PMID:33883980
Bioinformatics and In Vitro Studies Reveal the Importance of p53, PPARG and Notch Signaling Pathway in Inhibition of Breast Cancer Stem Cells by Hesperetin. PMID:33880358
Identification of key genes and pathways in discoid lupus skin via bioinformatics analysis. PMID:33879674
In silico Structural, Functional and Phylogenetic Analyses of cellulase from Ruminococcus albus. PMID:33871739
Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis. PMID:33871358
miR-155-5p predictive role to decelerate foam cell atherosclerosis through CD36, VAV3, and SOCS1 pathway. PMID:33869908
Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance. PMID:33869219
SeBioGraph: Semi-supervised Deep Learning for the Graph via Sustainable Knowledge Transfer. PMID:33867966
Prognostic value of LRRC4C in Colon and Gastric Cancers correlates with Tumour Microenvironment Immunity. PMID:33867855
A SNP of HD-ZIP I transcription factor leads to distortion of trichome morphology in cucumber (Cucumis sativus L.). PMID:33863289
Bioinformatic Analysis of Key Genes and Pathways Related to Keloids. PMID:33860039
Comparison of metastatic castration-resistant prostate cancer in bone with other sites: clinical characteristics, molecular features and immune status. PMID:33859877
Synthetic lethality-mediated precision oncology via the tumor transcriptome. PMID:33857424
Prediction of single-cell mechanisms for disease progression in hypertrophic remodelling by a trans-omics approach. PMID:33854108
Molecular Network Analysis in Rabies Pathogenesis Using Cooperative Game Theory. PMID:33850945
The influence of lncRNAs on the prognosis of prostate cancer based on TCGA database. PMID:33850764
Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways. PMID:33846781
iDEP Web Application for RNA-Seq Data Analysis. PMID:33835455
Age-Dependent Sensitivity to the Neurotoxic Environmental Metabolite, 1,2-Diacetylbenzene. PMID:33820880
Application and evaluation of knowledge graph embeddings in biomedical data. PMID:33816992
Development and Validation of a Hypoxia-Associated Prognostic Signature Related to Osteosarcoma Metastasis and Immune Infiltration. PMID:33816483
Network Pharmacology Analysis of Traditional Chinese Medicine Formula Shuang Di Shou Zhen Tablets Treating Nonexudative Age-Related Macular Degeneration. PMID:33815556
Gene Expression Changes of Humans with Primary Mitral Regurgitation and Reduced Left Ventricular Ejection Fraction. PMID:33810615
Prognostic and Functional Significant of Heat Shock Proteins (HSPs) in Breast Cancer Unveiled by Multi-Omics Approaches. PMID:33810095
A New Epigenetic Model to Stratify Glioma Patients According to Their Immunosuppressive State. PMID:33807997
Quantitative Proteomics Analysis of Berberine-Treated Colon Cancer Cells Reveals Potential Therapy Targets. PMID:33806918
Identification of Decrease in TRiC Proteins as Novel Targets of Alpha-Amanitin-Derived Hepatotoxicity by Comparative Proteomic Analysis In Vitro. PMID:33803263
OsCBE1, a Substrate Receptor of Cullin4-Based E3 Ubiquitin Ligase, Functions as a Regulator of Abiotic Stress Response and Productivity in Rice. PMID:33801226
Network pharmacology-based and clinically relevant prediction of active ingredients and potential targets of Chinese herbs on stage IV lung adenocarcinoma patients. PMID:33797608
Integrative Analysis of the Expression of SIGLEC Family Members in Lung Adenocarcinoma via Data Mining. PMID:33796453
m6A RNA Methylation Regulators Impact Prognosis and Tumor Microenvironment in Renal Papillary Cell Carcinoma. PMID:33796449
Immune Interaction Map of Human SARS-CoV-2 Target Genes: Implications for Therapeutic Avenues. PMID:33796097
Identification of vital prognostic genes related to tumor microenvironment in pheochromocytoma and paraganglioma based on weighted gene co-expression network analysis. PMID:33795528
Identification of blood-derived candidate gene markers and a new 7-gene diagnostic model for multiple sclerosis. PMID:33795012
Ubiquitylome analysis reveals a central role for the ubiquitin-proteasome system in plant innate immunity. PMID:33793954
Kingdom-wide analysis of the evolution of the plant type III polyketide synthase superfamily. PMID:33793871
DECO: a framework for jointly analyzing de novo and rare case/control variants, and biological pathways. PMID:33791774
Uterine infusion of conceptus fragments changes the protein profile from cyclic mares. PMID:33791032
Epigenetic effects toward new insights as potential therapeutic target in B-thalassemia. PMID:33788050
Six genes involved in prognosis of hepatocellular carcinoma identified by Cox hazard regression. PMID:33784984
Novelty and Convergence in Adaptation to Whole Genome Duplication. PMID:33783509
Proteomic Profiling of Lysine Acetylation Indicates Mitochondrial Dysfunction in the Hippocampus of Gut Microbiota-Absent Mice. PMID:33776647
PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. PMID:33764618
High Glucose Causes Distinct Expression Patterns of Primary Human Skin Cells by RNA Sequencing. PMID:33763026
The identification of neutrophils-mediated mechanisms and potential therapeutic targets for the management of sepsis-induced acute immunosuppression using bioinformatics. PMID:33761636
PecanPy: a fast, efficient, and parallelized Python implementation of node2vec. PMID:33760066
Overexpression of Taspase 1 Predicts Poor Prognosis in Patients with Hepatocellular Carcinoma. PMID:33758547
Herb-target virtual screening and network pharmacology for prediction of molecular mechanism of Danggui Beimu Kushen Wan for prostate cancer. PMID:33758314
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) versus adult T-cell leukemia/lymphoma (ATLL). PMID:33757561
Overexpression of CCNE1 confers a poorer prognosis in triple-negative breast cancer identified by bioinformatic analysis. PMID:33757543
Comprehensive investigation of the clinical significance of long non-coding RNA HOXA-AS2 in acute myeloid leukemia using genome-wide RNA sequencing dataset. PMID:33754013
MET transcriptional regulator/serine peptidase inhibitor kunitz type 1 panel operating through HGF/c-MET axis as a prognostic signature in pan-cancer. PMID:33751856
Mammalian Flavoproteome Analysis Using Label-Free Quantitative Mass Spectrometry. PMID:33751441
Removing auto-activators from yeast-two-hybrid assays by conditional negative selection. PMID:33750818
FixJ family regulator AcfR of Azorhizobium caulinodans is involved in symbiosis with the host plant. PMID:33750295
Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry. PMID:33747361
Exploring the Oxidative Stress Mechanism of Buyang Huanwu Decoction in Intervention of Vascular Dementia Based on Systems Biology Strategy. PMID:33747352
Identification of Pivotal MicroRNAs and Target Genes Associated with Persistent Atrial Fibrillation Based on Bioinformatics Analysis. PMID:33747117
Comparative transcriptomic analysis of the different developmental stages of ovary in red swamp crayfish Procambarus clarkii. PMID:33745451
Evolution of mammalian longevity: age-related increase in autophagy in bats compared to other mammals. PMID:33744862
Drug repurposing against breast cancer by integrating drug-exposure expression profiles and drug-drug links based on graph neural network. PMID:33739367
Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses. PMID:33732416
Identification of potential markers for differentiating epithelial ovarian cancer from ovarian low malignant potential tumors through integrated bioinformatics analysis. PMID:33726773
Integrated Protein-Protein Interaction and Weighted Gene Co-expression Network Analysis Uncover Three Key Genes in Hepatoblastoma. PMID:33718368
Methyl Jasmonate Cytotoxicity and Chemosensitization of T Cell Lymphoma In Vitro Is Facilitated by HK 2, HIF-1α, and Hsp70: Implication of Altered Regulation of Cell Survival, pH Homeostasis, Mitochondrial Functions. PMID:33716751
In silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19. PMID:33716737
Facile accelerated specific therapeutic (FAST) platform develops antisense therapies to counter multidrug-resistant bacteria. PMID:33712689
Identification of novel therapeutic targets for contrast induced acute kidney injury (CI-AKI): alpha blockers as a therapeutic strategy for CI-AKI. PMID:33711514
Integrated analysis of RNA-binding proteins in thyroid cancer. PMID:33711033
Short loop functional commonality identified in leukaemia proteome highlights crucial protein sub-networks. PMID:33709075
Identification of drug compounds for keloids and hypertrophic scars: drug discovery based on text mining and DeepPurpose. PMID:33708974
Coronary artery disease: differential expression of ceRNAs and interaction analyses. PMID:33708856
A Potential Autophagy-Related Competing Endogenous RNA Network and Corresponding Diagnostic Efficacy in Schizophrenia. PMID:33708146
PRYNT: a tool for prioritization of disease candidates from proteomics data using a combination of shortest-path and random walk algorithms. PMID:33707596
Multi-factor mediated functional modules identify novel classification of ulcerative colitis and functional gene panel. PMID:33707495
A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models. PMID:33705438
MARK2 phosphorylates eIF2α in response to proteotoxic stress. PMID:33705388
Calcium-binding and coiled-coil domain 2 promotes the proliferation and suppresses apoptosis of prostate cancer cells. PMID:33692836
Frequent Subgraph Mining of Functional Interaction Patterns Across Multiple Cancers. PMID:33691023
Bioinformatis analysis reveals possible molecular mechanism of PXR on regulating ulcerative colitis. PMID:33686088
Identification and validation of three core genes in p53 signaling pathway in hepatitis B virus-related hepatocellular carcinoma. PMID:33685467
Analysis of MicroRNAs Associated With Carotid Atherosclerotic Plaque Rupture With Thrombosis. PMID:33679879
Methylation of rRNA as a host defense against rampant group II intron retrotransposition. PMID:33678171
HIR V2: a human interactome resource for the biological interpretation of differentially expressed genes via gene set linkage analysis. PMID:33677507
Functional genomic analyses highlight a shift in Gpr17-regulated cellular processes in oligodendrocyte progenitor cells and underlying myelin dysregulation in the aged mouse cerebrum. PMID:33675110
The Alphaviral Capsid Protein Inhibits IRAK1-Dependent TLR Signaling. PMID:33673546
Transcriptome Analysis Reveals the Genes Involved in Bifidobacterium Longum FGSZY16M3 Biofilm Formation. PMID:33672820
Potential Treatment of Lysosomal Storage Disease through Modulation of the Mitochondrial-Lysosomal Axis. PMID:33671306
Ionizing Radiation Protein Biomarkers in Normal Tissue and Their Correlation to Radiosensitivity: A Systematic Review. PMID:33669522
Identify potential miRNA-mRNA regulatory networks contributing to high-risk neuroblastoma. PMID:33666785
Weighted gene co-expression network analysis to identify key modules and hub genes related to hyperlipidaemia. PMID:33663541
Protein Interactomes of Streptococcus mutans YidC1 and YidC2 Membrane Protein Insertases Suggest SRP Pathway-Independent- and -Dependent Functions, Respectively. PMID:33658280
Revealing the link between macrophage in microenvironment of osteosarcoma and poor prognosis by utilizing the Integrated analysis. PMID:33657763
Large-scale discovery of protein interactions at residue resolution using co-evolution calculated from genomic sequences. PMID:33654096
Proteomics Analyses Reveal Functional Differences between Exosomes of Mesenchymal Stem Cells Derived from The Umbilical Cord and Those Derived from The Adipose Tissue. PMID:33650823
Comprehensive analysis of AHL gene family and their expression under drought stress and ABA treatment in Populus trichocarpa. PMID:33643717
Protein kinase TgCDPK7 regulates vesicular trafficking and phospholipid synthesis in Toxoplasma gondii. PMID:33635921
Exploring the mechanisms underlying the therapeutic effect of Salvia miltiorrhiza in diabetic nephropathy using network pharmacology and molecular docking. PMID:33634308
Knockdown of RIPK2 Inhibits Proliferation and Migration, and Induces Apoptosis via the NF-κB Signaling Pathway in Gastric Cancer. PMID:33633788
Exploring the genetic architecture of feed efficiency traits in chickens. PMID:33633287
PFP-WGAN: Protein function prediction by discovering Gene Ontology term correlations with generative adversarial networks. PMID:33630862
miR-193a-3p Promotes the Invasion, Migration, and Mesenchymal Transition in Glioma through Regulating BTRC. PMID:33628829
Ursolic Acid Regulates Cell Cycle and Proliferation in Colon Adenocarcinoma by Suppressing Cyclin B1. PMID:33628185
Microarray analysis of Arabidopsis thaliana exposed to single and mixed infections with Cucumber mosaic virus and turnip viruses. PMID:33627959
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics. PMID:33627808
Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer's disease. PMID:33627625
Single-cell transcriptomic profiling and characterization of endothelial progenitor cells: new approach for finding novel markers. PMID:33627177
The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection. PMID:33623002
Identification of key pathways and genes in polycystic ovary syndrome via integrated bioinformatics analysis and prediction of small therapeutic molecules. PMID:33622336
Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization. PMID:33620318
Independent component analysis based gene co-expression network inference (ICAnet) to decipher functional modules for better single-cell clustering and batch integration. PMID:33619563
Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis. PMID:33619278
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition. PMID:33613118
An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Machinery for ZIKV and DENV Replication. PMID:33610792
Robust inference of kinase activity using functional networks. PMID:33608514
Zinc transporter ZIP7 is a novel determinant of ferroptosis. PMID:33608508
Liquid Chromatography and Tandem Mass Spectrometry in Label-Free Protein Quantification of Zebrafish (Danio rerio) Eggs. PMID:33606239
SUV39H2 epigenetic silencing controls fate conversion of epidermal stem and progenitor cells. PMID:33604655
A Deep Look into the Program of Rapid Tumor Growth of Hepatocellular Carcinoma. PMID:33604252
High expression of MCM10 is predictive of poor outcomes in lung adenocarcinoma. PMID:33604163
Transcriptomic Signatures and Functional Network Analysis of Chronic Rhinosinusitis With Nasal Polyps. PMID:33603773
Identification of potential therapeutic target of naringenin in breast cancer stem cells inhibition by bioinformatics and in vitro studies. PMID:33603536
Optimized expression of Hfq protein increases Escherichia coli growth. PMID:33602295
Investigation of allele specific expression in various tissues of broiler chickens using the detection tool VADT. PMID:33597613
Study on cocoonase, sericin, and degumming of silk cocoon: computational and experimental. PMID:33594479
Development and analysis of long non-coding RNA-associated competing endogenous RNA network for osteosarcoma metastasis. PMID:33593435
Regional Differences in S-Nitrosylation in the Cortex, Striatum, and Hippocampus of Juvenile Male Mice. PMID:33591546
Long Non-coding RNA BTG3-7:1 and JUND Co-regulate C21ORF91 to Promote Triple-Negative Breast Cancer Progress. PMID:33585557
Immune Cluster and PPI Network Analyses Identified CXCR3 as a Key Node of Immunoregulation in Head and Neck Cancer. PMID:33585188
Proteomic Analysis of Listeria monocytogenes FBUNT During Biofilm Formation at 10°C in Response to Lactocin AL705. PMID:33584610
Identification of Potential Biomarkers Associated with Prognosis in Gastric Cancer via Bioinformatics Analysis. PMID:33582701
Targeting critical kinases and anti-apoptotic molecules overcomes steroid resistance in MLL-rearranged leukaemia. PMID:33581643
The role of ARHGAP9: clinical implication and potential function in acute myeloid leukemia. PMID:33579308
MSN, MWCNT and ZnO nanoparticle-induced CHO-K1 cell polarisation is linked to cytoskeleton ablation. PMID:33579304
m6A modification patterns and tumor immune landscape in clear cell renal carcinoma. PMID:33574053
Post-Translational Modifications That Drive Prostate Cancer Progression. PMID:33572160
miR-16-5p Promotes Erythroid Maturation of Erythroleukemia Cells by Regulating Ribosome Biogenesis. PMID:33572085
Identification and characterization of MADS box gene family in pigeonpea for their role during floral transition. PMID:33569264
Divergence in Coding Sequence and Expression of Different Functional Categories of Immune Genes between Two Wild Rodent Species. PMID:33565592
Expression of cell divisioncycle-associated genes and their prognostic significance in hepatocellular carcinoma. PMID:33564348
Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive Bioinformatics Analysis. PMID:33564304
Common differentially expressed genes and pathways correlating both coronary artery disease and atrial fibrillation. PMID:33564282
RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing. PMID:33564070
Transcriptome analysis and molecular mechanism of linseed (Linum usitatissimum L.) drought tolerance under repeated drought using single-molecule long-read sequencing. PMID:33563217
ComHub: Community predictions of hubs in gene regulatory networks. PMID:33563211
Heat shock proteins and small nucleolar RNAs are dysregulated in a Drosophila model for feline hypertrophic cardiomyopathy. PMID:33561224
SUMO pathway, blood coagulation and oxidative stress in SARS-CoV-2 infection. PMID:33558851
Critical role of Aquaporin-1 and telocytes in infantile hemangioma response to propranolol beta blockade. PMID:33558238
A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis. PMID:33556465
TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation. PMID:33554859
The evolutionary conserved iron-sulfur protein TCR controls P700 oxidation in photosystem I. PMID:33554065
Mechanism and Molecular Network of RBM8A-Mediated Regulation of Oxaliplatin Resistance in Hepatocellular Carcinoma. PMID:33552961
CSF3 Is a Potential Drug Target for the Treatment of COVID-19. PMID:33551833
Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis. PMID:33551818
Gonadal Cycle-Dependent Expression of Genes Encoding Peptide-, Growth Factor-, and Orphan G-Protein-Coupled Receptors in Gonadotropin- Releasing Hormone Neurons of Mice. PMID:33551743
Salviae miltiorrhizae and ligustrazine hydrochloride injection combined with mecobalamin for treating diabetic peripheral neuropathy: A protocol for systematic review and meta-analysis. PMID:33546016
Prediction and analysis of hub genes between glioblastoma and low-grade glioma using bioinformatics analysis. PMID:33545929
The mutational landscape of spinal chordomas and their sensitive detection using circulating tumor DNA. PMID:33543146
Lyso-phosphatidylethanolamine primes the plant immune system and promotes basal resistance against hemibiotrophic pathogens. PMID:33536000
Myeloid-derived suppressor cell (MDSC) key genes analysis in rat anti-CD28-induced immune tolerance kidney transplantation. PMID:33532310
Identification of novel biomarkers and candidate small-molecule drugs in cutaneous melanoma by comprehensive gene microarrays analysis. PMID:33531976
Harnessing Machine Learning To Unravel Protein Degradation in Escherichia coli. PMID:33531410
Screening the key genes of prognostic value in the microenvironment for head and neck squamous cell carcinoma. PMID:33530209
Bone marrow stromal cells derived exosomal miR-10a and miR-16 may be involved in progression of patients with multiple myeloma by regulating EPHA8 or IGF1R/CCND1. PMID:33530159
Rab7-harboring vesicles are carriers of the transferrin receptor through the biosynthetic secretory pathway. PMID:33523982
Study of micro-trichome (mict) reveals novel connections between transcriptional regulation of multicellular trichome development and specific metabolism in cucumber. PMID:33518711
Multi-omic regulatory networks capture downstream effects of kinase inhibition in Mycobacterium tuberculosis. PMID:33514755
Language Impairment with a Partial Duplication of DOCK8. PMID:33510598
A parsimonious approach for recognizing SARS-CoV-2 and host interactions. PMID:33506962
Cryptotanshinone Is a Intervention for ER-Positive Breast Cancer: An Integrated Approach to the Study of Natural Product Intervention Mechanisms. PMID:33505309
Inflammation and regulatory T cell genes are differentially expressed in peripheral blood mononuclear cells of Parkinson's disease patients. PMID:33504893
Weighted gene co-expression network analysis identifies modules and functionally enriched pathways in the lactation process. PMID:33504890
Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. PMID:33503434
Prebiotic Colloidal Oat Supports the Growth of Cutaneous Commensal Bacteria Including S. epidermidis and Enhances the Production of Lactic Acid. PMID:33500646
Genomic analysis of WD40 protein family in the mango reveals a TTG1 protein enhances root growth and abiotic tolerance in Arabidopsis. PMID:33500544
Network pharmacology integrated molecular docking reveals the bioactive components and potential targets of Morinda officinalis-Lycium barbarum coupled-herbs against oligoasthenozoospermia. PMID:33500463
From Transcriptomics to Treatment in Inherited Optic Neuropathies. PMID:33499292
Characterization of Odontogenic Differentiation from Human Dental Pulp Stem Cells Using TMT-Based Proteomic Analysis. PMID:33490242
Enhanced expression of queuine tRNA-ribosyltransferase 1 (QTRT1) predicts poor prognosis in lung adenocarcinoma. PMID:33490170
iMPTCE-Hnetwork: A Multilabel Classifier for Identifying Metabolic Pathway Types of Chemicals and Enzymes with a Heterogeneous Network. PMID:33488764
Periostin Contributes to Immunoglobulin a Nephropathy by Promoting the Proliferation of Mesangial Cells: A Weighted Gene Correlation Network Analysis. PMID:33488671
RIG-I Has a Role in Immunity Against Haemonchus contortus, a Gastrointestinal Parasite in Ovis aries: A Novel Report. PMID:33488570
Comparative analysis on the anti-inflammatory/immune effect of mesenchymal stem cell therapy for the treatment of pulmonary arterial hypertension. PMID:33479312
Label-Free Comparative Proteomics Analysis Revealed Heat Stress Responsive Mechanism in Hypsizygus marmoreus. PMID:33469447
Chlamydia trachomatis TmeA Directly Activates N-WASP To Promote Actin Polymerization and Functions Synergistically with TarP during Invasion. PMID:33468693
A chicken DNA methylation clock for the prediction of broiler health. PMID:33462334
Regulation of Gut Microbiota Disrupts the Glucocorticoid Receptor Pathway and Inflammation-related Pathways in the Mouse Hippocampus. PMID:33462159
Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death. PMID:33461384
Bioinformatics and system biology approach to identify the influences of COVID-19 on cardiovascular and hypertensive comorbidities. PMID:33458761
C3, C3AR1, HLA-DRA, and HLA-E as potential prognostic biomarkers for renal clear cell carcinoma. PMID:33457236
Danhong Injection Alleviates Cardiac Fibrosis via Preventing the Hypermethylation of Rasal1 and Rassf1 in TAC Mice. PMID:33456666
Comprehensive computational target fishing approach to identify Xanthorrhizol putative targets. PMID:33452398
DNAJB4 identified as a potential breast cancer marker: evidence from bioinformatics analysis and basic experiments. PMID:33447546
Identification of Four Genes as Prognosis Signatures in Lung Adenocarcinoma Microenvironment. PMID:33447073
Pseudomonas aeruginosa reverse diauxie is a multidimensional, optimized, resource utilization strategy. PMID:33446818
Identifying of biomarkers associated with gastric cancer based on 11 topological analysis methods of CytoHubba. PMID:33446695
Dysregulated Dynein-Mediated Trafficking of Nephrin Causes INF2-related Podocytopathy. PMID:33443052
Multiple microarray analyses identify key genes associated with the development of Non-Small Cell Lung Cancer from Chronic Obstructive Pulmonary Disease. PMID:33442399
Transglutaminase 2 crosslinks the glutathione S-transferase tag, impeding protein-protein interactions of the fused protein. PMID:33441971
Internetwork connectivity of molecular networks across species of life. PMID:33441907
Genes Influencing Phage Host Range in Staphylococcus aureus on a Species-Wide Scale. PMID:33441407
Classification of Cancer Types Using Graph Convolutional Neural Networks. PMID:33437754
Tracing species replacement in Iberian marbled newts. PMID:33437438
Post-transcriptional circadian regulation in macrophages organizes temporally distinct immunometabolic states. PMID:33436377
PTGER3 and MMP-2 play potential roles in diabetic nephropathy via competing endogenous RNA mechanisms. PMID:33435900
Comparative RNA-Seq analysis unfolds a complex regulatory network imparting yellow mosaic disease resistance in mungbean [Vigna radiata (L.) R. Wilczek]. PMID:33434234
Quantitative proteomics analysis of Angiostrongylus vasorum-induced alterations in dog serum sheds light on the pathogenesis of canine angiostrongylosis. PMID:33431914
SmartGraph: a network pharmacology investigation platform. PMID:33430980
Exploration of the immune cell infiltration-related gene signature in the prognosis of melanoma. PMID:33428606
Deregulation of extracellular matrix modeling with molecular prognostic markers revealed by transcriptome sequencing and validations in Oral Tongue squamous cell carcinoma. PMID:33420101
Different Gene Networks Are Disturbed by Zika Virus Infection in A Mouse Microcephaly Model. PMID:33418086
PC2P: Parameter-free network-based prediction of protein complexes. PMID:33416831
Systematical Identification of the Protective Effect of Danhong Injection and BuChang NaoXinTong Capsules on Transcription Factors in Cerebral Ischemia Mice Brain. PMID:33414894
Network propagation of rare variants in Alzheimer's disease reveals tissue-specific hub genes and communities. PMID:33411734
Integration of gene expression data identifies key genes and pathways in colorectal cancer. PMID:33411100
New insights on key genes involved in drought stress response of barley: gene networks reconstruction, hub, and promoter analysis. PMID:33409810
The histone methyltransferase inhibitor A-366 enhances hemoglobin expression in erythroleukemia cells upon co-exposure with chemical inducers in culture. PMID:33407944
Bioinformatics analysis of common key genes and pathways of intracranial, abdominal, and thoracic aneurysms. PMID:33407182
Label-free proteomic analysis of serum exosomes from paroxysmal atrial fibrillation patients. PMID:33407078
Identification of Seven Cell Cycle-Related Genes with Unfavorable Prognosis and Construction of their TF-miRNA-mRNA regulatory network in Breast Cancer. PMID:33403032
Genome-wide identification of Chiari malformation type I associated candidate genes and chromosomal variations. PMID:33402871
A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions. PMID:33402532
DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3. PMID:33393494
Immunological Role and Prognostic Value of APBB1IP in Pan-Cancer Analysis. PMID:33391455
Identification of Critical Genes and Proteins for Stent Restenosis Induced by Esophageal Benign Hyperplasia in Esophageal Cancer. PMID:33391336
Identification of the Biomarkers and Pathological Process of Heterotopic Ossification: Weighted Gene Co-Expression Network Analysis. PMID:33391181
Single-cell transcriptomics identifies limbal stem cell population and cell types mapping its differentiation trajectory in limbal basal epithelium of human cornea. PMID:33388438
Inference of Genetic Networks From Time-Series and Static Gene Expression Data: Combining a Random-Forest-Based Inference Method With Feature Selection Methods. PMID:33384716
Evaluation of Male Fertility-Associated Loci in a European Population of Patients with Severe Spermatogenic Impairment. PMID:33383876
A Multi-Pronged Computational Pipeline for Prioritizing Drug Target Strategies for Latent Tuberculosis. PMID:33381491
Comparative Analysis of Systemic and Tumor Microenvironment Proteomes From Children With B-Cell Acute Lymphocytic Leukemia at Diagnosis and After Induction Treatment. PMID:33381445
Effect of let-7c on the PI3K/Akt/FoxO signaling pathway in hepatocellular carcinoma. PMID:33376529
P4HB: A novel diagnostic and prognostic biomarker for bladder carcinoma. PMID:33376528
Intrinsic Disorder in Plant Transcription Factor Systems: Functional Implications. PMID:33371315
The role of the MAD2-TLR4-MyD88 axis in paclitaxel resistance in ovarian cancer. PMID:33370338
Identification of Hub Prognosis-Associated Oxidative Stress Genes in Pancreatic Cancer Using Integrated Bioinformatics Analysis. PMID:33363572
Identification of Pathways and Key Genes in Venous Remodeling After Arteriovenous Fistula by Bioinformatics Analysis. PMID:33363475
Phosphatase and Tensin Homolog Mutation in Immune Cell Infiltration and Clinicopathological Features of Low-Grade Gliomas. PMID:33363203
Bioinformatics Analysis of Actin Molecules: Why Quantity Does Not Translate Into Quality? PMID:33362870
Identification and Validation of Potential Pathogenic Genes and Prognostic Markers in ESCC by Integrated Bioinformatics Analysis. PMID:33362844
A Network-Based Analysis Reveals the Mechanism Underlying Vitamin D in Suppressing Cytokine Storm and Virus in SARS-CoV-2 Infection. PMID:33362771
Global insights to drought stress perturbed genes in oat (Avena sativa L.) seedlings using RNA sequencing. PMID:33356830
Scottish soldiers from the Battle of Dunbar 1650: A prosopographical approach to a skeletal assemblage. PMID:33347451
Bioinformatics analysis identifies COL1A1, THBS2 and SPP1 as potential predictors of patient prognosis and immunotherapy response in gastric cancer. PMID:33345281
Efficacy of Compound Herbal Medicine Tong-Xie-Yao-Fang for Acute Radiation Enteritis and Its Potential Mechanisms: Evidence from Transcriptome Analysis. PMID:33344641
Proteomic analysis of anti-angiogenic effects by conbercept in the mice with oxygen induced retinopathy. PMID:33344181
Inhibition of FGF and TGF-β Pathways in hESCs Identify STOX2 as a Novel SMAD2/4 Cofactor. PMID:33339109
Key pathways in prostate cancer with SPOP mutation identified by bioinformatic analysis. PMID:33336059
Identification and characterization of critical genes associated with tamoxifen resistance in breast cancer. PMID:33335811
Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human Life. PMID:33329546
Identification of Hub Genes of Mesio Temporal Lobe Epilepsy and Prognostic Biomarkers of Brain Low-grade Gliomas Based on Bioinformatics Analysis. PMID:33327771
Cyano Enone-Bearing Triterpenoid Soloxolone Methyl Inhibits Epithelial-Mesenchymal Transition of Human Lung Adenocarcinoma Cells In Vitro and Metastasis of Murine Melanoma In Vivo. PMID:33327637
Network pharmacology-based strategy for predicting therapy targets of Tripterygium wilfordii on acute myeloid leukemia. PMID:33327305
Integrated Multichip Analysis Identifies Potential Key Genes in the Pathogenesis of Nonalcoholic Steatohepatitis. PMID:33324350
Tumor-associated macrophage polarization promotes the progression of esophageal carcinoma. PMID:33323552
Postnatal Growth Restriction in Mice Alters Cardiac Protein Composition and Leads to Functional Impairment in Adulthood. PMID:33322681
Convergent network effects along the axis of gene expression during prostate cancer progression. PMID:33317623
Comprehensive analysis of immune infiltration and gene expression for predicting survival in patients with sarcomas. PMID:33316779
Network Re-Wiring During Allostery and Protein-Protein Interactions: A Graph Spectral Approach. PMID:33315220
Hierarchical Canonical Correlation Analysis Reveals Phenotype, Genotype, and Geoclimate Associations in Plants. PMID:33313545
Weighted gene co-expression network analysis identifies FCER1G as a key gene associated with diabetic kidney disease. PMID:33313172
The mRNA landscape profiling reveals potential biomarkers associated with acute kidney injury AKI after kidney transplantation. PMID:33312771
Profiling Analysis Reveals the Crucial Role of the Endogenous Peptides in Bladder Cancer Progression. PMID:33311987
Identification of Transcriptional Variation in Aortic Remodeling Using a Murine Transverse Aortic Constriction (TAC) Model. PMID:33304927
Identification of key genes controlling cancer stem cell characteristics in gastric cancer. PMID:33304447
Comprehensive genomic and immunophenotypic analysis of CD4 T cell infiltrating human triple-negative breast cancer. PMID:33301062
Bioinformatics Analysis Identifies Key Genes and Pathways in Acute Myeloid Leukemia Associated with DNMT3A Mutation. PMID:33299888
Identification of Functional Genes in Pterygium Based on Bioinformatics Analysis. PMID:33299863
An Integrated Bioinformatic Analysis of the S100 Gene Family for the Prognosis of Colorectal Cancer. PMID:33294444
Tandem Mass Tag-based quantitative proteomics analysis of metabolic associated fatty liver disease induced by high fat diet in mice. PMID:33292312
Epigenetic signature predicts overall survival clear cell renal cell carcinoma. PMID:33292239
2-oxoglutarate-dependent dioxygenases: A renaissance in attention for ascorbic acid in plants. PMID:33290424
Integrated proteome and phosphoproteome analyses of peripheral blood mononuclear cells in primary Sjögren syndrome patients. PMID:33290261
Molecular signature comprising 11 platelet-genes enables accurate blood-based diagnosis of NSCLC. PMID:33287695
Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro. PMID:33287422
White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment. PMID:33285300
Interaction of preimplantation factor with the global bovine endometrial transcriptome. PMID:33284816
Statin therapy and risk of Alzheimer's and age-related neurodegenerative diseases. PMID:33283039
Systematic Identification of Key Functional Modules and Genes in Gastric Cancer. PMID:33282955
TTK, CDC25A, and ESPL1 as Prognostic Biomarkers for Endometrial Cancer. PMID:33282948
Identifying MMP14 and COL12A1 as a potential combination of prognostic biomarkers in pancreatic ductal adenocarcinoma using integrated bioinformatics analysis. PMID:33282565
miR-224, miR-147b and miR-31 associated with lymph node metastasis and prognosis for lung adenocarcinoma by regulating PRPF4B, WDR82 or NR3C2. PMID:33282547
DRIM: A Web-Based System for Investigating Drug Response at the Molecular Level by Condition-Specific Multi-Omics Data Integration. PMID:33281870
Role of COL3A1 and POSTN on Pathologic Stages of Esophageal Cancer. PMID:33280513
Overexpressed miR-335-5p reduces atherosclerotic vulnerable plaque formation in acute coronary syndrome. PMID:33277957
Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia. PMID:33277547
High levels of glucose alter Physcomitrella patens metabolism and trigger a differential proteomic response. PMID:33275616
Bacteria use structural imperfect mimicry to hijack the host interactome. PMID:33275611
Informatics Inference of Exercise-Induced Modulation of Brain Pathways Based on Cerebrospinal Fluid Micro-RNAs in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. PMID:33274349
Identification of adhesion-associated DNA methylation patterns in the peripheral nervous system. PMID:33273976
Aqueous Fibronectin Correlates With Severity of Macular Edema and Visual Acuity in Patients With Branch Retinal Vein Occlusion: A Proteome Study. PMID:33270842
Expression and Bioinformatics-Based Functional Analysis of UAP1 in Lung Adenocarcinoma. PMID:33269005
An Automated Functional Annotation Pipeline That Rapidly Prioritizes Clinically Relevant Genes for Autism Spectrum Disorder. PMID:33261099
A Novel Nanoproteomic Approach for the Identification of Molecular Targets Associated with Thyroid Tumors. PMID:33260544
Identification of potential biomarkers for lung adenocarcinoma. PMID:33251353
Multi-omics integration in biomedical research - A metabolomics-centric review. PMID:33248648
Introducing APOA1 as a key protein in COVID-19 infection: a bioinformatics approach. PMID:33244380
Single-cell network biology for resolving cellular heterogeneity in human diseases. PMID:33244151
OTUB1 Recruits Tumor Infiltrating Lymphocytes and Is a Prognostic Marker in Digestive Cancers. PMID:33240928
Tumor Derived SIGLEC Family Genes May Play Roles in Tumor Genesis, Progression, and Immune Microenvironment Regulation. PMID:33240817
Integrated analysis of lncRNA and mRNA reveals novel insights into cashmere fineness in Tibetan cashmere goats. PMID:33240606
Polyphyllin VII suppresses cell proliferation, the cell cycle and cell migration in colorectal cancer. PMID:33240431
Multiple functions of TBCK protein in neurodevelopment disorders and tumors. PMID:33240423
Identifying a Potential Key Gene, TIMP1, Associated with Liver Metastases of Uveal Melanoma by Weight Gene Co-Expression Network Analysis. PMID:33239893
Initial response of ovarian tissue transcriptome to vitrification or microwave-assisted dehydration in the domestic cat model. PMID:33238878
The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets. PMID:33237311
Identification of key genes in osteoarthritis using bioinformatics, principal component analysis and meta-analysis. PMID:33235627
An integrative atlas of chicken long non-coding genes and their annotations across 25 tissues. PMID:33235280
An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14. PMID:33234594
Overexpression of DDR1 Promotes Migration, Invasion, Though EMT-Related Molecule Expression and COL4A1/DDR1/MMP-2 Signaling Axis. PMID:33234027
Exploring the Mechanism of Icariin in Osteoporosis Based on a Network Pharmacology Strategy. PMID:33230092
A photo-crosslinkable cartilage-derived extracellular matrix bioink for auricular cartilage tissue engineering. PMID:33227486
Identification of Crucial lncRNAs, miRNAs, mRNAs, and Potential Therapeutic Compounds for Polycystic Ovary Syndrome by Bioinformatics Analysis. PMID:33224973
Comprehensive circular RNA expression profiling constructs a ceRNA network and identifies hsa_circ_0000673 as a novel oncogene in distal cholangiocarcinoma. PMID:33221765
The strength and form of natural selection on transcript abundance in the wild. PMID:33219570
Predicted rat interactome database and gene set linkage analysis. PMID:33216897
ClusterM: a scalable algorithm for computational prediction of conserved protein complexes across multiple protein interaction networks. PMID:33208103
Identification of Prognosis-Related Genes in Bladder Cancer Microenvironment across TCGA Database. PMID:33204728
Silencing KIF14 reverses acquired resistance to sorafenib in hepatocellular carcinoma. PMID:33203790
Widespread regulation of gene expression by glucocorticoids in chondrocytes from patients with osteoarthritis as determined by RNA-Seq. PMID:33203447
TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages. PMID:33198789
DNA sequencing of anatomy lab cadavers to provide hands-on precision medicine introduction to medical students. PMID:33198737
Integrated transcriptome meta-analysis of pancreatic ductal adenocarcinoma and matched adjacent pancreatic tissues. PMID:33194391
Novel Gene Signature Reveals Prognostic Model in Acute Myeloid Leukemia. PMID:33193652
Identification of Characteristic Genomic Markers in Human Hepatoma HuH-7 and Huh7.5.1-8 Cell Lines. PMID:33193621
Identification of Potential Core Genes Associated With the Progression of Stomach Adenocarcinoma Using Bioinformatic Analysis. PMID:33193601
Systematic Analysis of Lysine Lactylation in the Plant Fungal Pathogen Botrytis cinerea. PMID:33193272
Global Proteomic Analysis of Lysine Crotonylation in the Plant Pathogen Botrytis cinerea. PMID:33193151
Prediction of Alzheimer's disease using multi-variants from a Chinese genome-wide association study. PMID:33188687
DeepciRGO: functional prediction of circular RNAs through hierarchical deep neural networks using heterogeneous network features. PMID:33183227
Quantitative Structure-Mutation-Activity Relationship Tests (QSMART) model for protein kinase inhibitor response prediction. PMID:33183223
Protein Corona Gold Nanoparticles Fingerprinting Reveals a Profile of Blood Coagulation Proteins in the Serum of HER2-Overexpressing Breast Cancer Patients. PMID:33182810
Bioinformatic Analysis Identifies Potential Key Genes in the Pathogenesis of Melanoma. PMID:33178610
High SEMA4C expression promotes the epithelial-mesenchymal transition and predicts poor prognosis in colorectal carcinoma. PMID:33177246
Integrated analysis of transcriptomic and metabolomic data demonstrates the significant role of pyruvate carboxylase in the progression of ovarian cancer. PMID:33177242
Mechanisms of miR‑128‑3p in inhibiting osteoblast differentiation from bone marrow‑derived mesenchymal stromal cells. PMID:33174052
Co‑expression network analysis identified specific miRNAs and genes in association with slow‑transit constipation. PMID:33174045
Integrated microarray analysis of key genes and a miRNA‑mRNA regulatory network of early‑onset preeclampsia. PMID:33173953
Data mining of immune-related prognostic genes in metastatic melanoma microenvironment. PMID:33169786
Biological network analysis with deep learning. PMID:33169146
[Over-expression of miR-519d alters gene expression profiles of cervical cancer SiHa cells]. PMID:33168510
Network and pathway enrichment analysis of Attention Deficit/Hyperactivity Disorder candidate genes. PMID:33165377
Diagnostic and prognostic values of forkhead box D4 gene in colonic adenocarcinoma. PMID:33165349
Combining bioinformatics techniques to explore the molecular mechanisms involved in pancreatic cancer metastasis and prognosis. PMID:33164330
HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients. PMID:33162805
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase. PMID:33156570
Bioinformatics Gene Analysis of Potential Biomarkers and Therapeutic Targets for Unstable Atherosclerotic Plaque-Related Stroke. PMID:33155176
Network Pharmacology-Based and Clinically Relevant Prediction of the Potential Targets of Chinese Herbs in Ovarian Cancer Patients. PMID:33150184
Ubiquitinome Profiling Reveals the Landscape of Ubiquitination Regulation in Rice Young Panicles. PMID:33147495
Role of the methionine cycle in the temperature-sensitive responses of potato plants to potato virus Y. PMID:33146443
Comprehensive Gene Expression Analysis Detects Global Reduction of Proteasome Subunits in Schizophrenia. PMID:33141894
Integrating systematic biological and proteomics strategies to explore the pharmacological mechanism of danshen yin modified on atherosclerosis. PMID:33140562
Investigating the expressions of miRNA-125b and TP53 in endometriosis. Does it underlie cancer-like features of endometriosis? A case-control study. PMID:33134795
Network Pharmacology-Based Strategy Reveals the Effects of Hedysarum multijugum Maxim.-Radix Salviae Compound on Oxidative Capacity and Cardiomyocyte Apoptosis in Rats with Diabetic Cardiomyopathy. PMID:33134388
An integrative multi-omics network-based approach identifies key regulators for breast cancer. PMID:33133424
Identification of Signatures of Prognosis Prediction for Melanoma Using a Hypoxia Score. PMID:33133157
Identification of the Significant Genes Regulated by Estrogen Receptor in Estrogen Receptor-Positive Breast Cancer and Their Expression Pattern Changes When Tamoxifen or Fulvestrant Resistance Occurs. PMID:33133141
Identification of Hub Genes Associated With Hepatocellular Carcinoma Using Robust Rank Aggregation Combined With Weighted Gene Co-expression Network Analysis. PMID:33133125
Antimicrobial Peptide Induced-Stress Renders Staphylococcus aureus Susceptible to Toxic Nucleoside Analogs. PMID:33133056
Prior Hypoxia Exposure Enhances Murine Microglial Inflammatory Gene Expression in vitro Without Concomitant H3K4me3 Enrichment. PMID:33132843
Lower expression of LINC00092 in lung adenocarcinoma might mean poorer prognosis: A study based on data mining and bioinformatics. PMID:33126385
Integrated TCGA and GEO analysis showed that SMAD7 is an independent prognostic factor for lung adenocarcinoma. PMID:33126329
Construction of novel mRNA-miRNA-lncRNA regulatory networks associated with prognosis of ovarian cancer. PMID:33123295
Oxidative stress and antioxidant defense in detoxification systems of snake venom-induced toxicity. PMID:33117427
Identification and Validation of Novel Genes in Anaplastic Thyroid Carcinoma via Bioinformatics Analysis. PMID:33116838
Analysis of Differential Expression Proteins of Paclitaxel-Treated Lung Adenocarcinoma Cell A549 Using Tandem Mass Tag-Based Quantitative Proteomics. PMID:33116610
Proteomics of regenerated tissue in response to a titanium implant with a bioactive surface in a rat tibial defect model. PMID:33116264
Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells. PMID:33116115
Biomarker Prioritisation and Power Estimation Using Ensemble Gene Regulatory Network Inference. PMID:33114263
Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity. PMID:33113859
Transcriptome analysis of the circadian clock gene BMAL1 deletion with opposite carcinogenic effects. PMID:33111200
Using Chromatin Accessibility to Delineate Therapeutic Subtypes in Pancreatic Cancer Patient-Derived Cell Lines. PMID:33111113
Comprehensive analysis of the expression of SLC30A family genes and prognosis in human gastric cancer. PMID:33110097
Insights into the mechanism of Arnebia euchroma on leukemia via network pharmacology approach. PMID:33109189
Involvement of NEK2 and its interaction with NDC80 and CEP250 in hepatocellular carcinoma. PMID:33109182
Horizontal meta-analysis identifies common deregulated genes across AML subgroups providing a robust prognostic signature. PMID:33108456
Comprehensive role of prostate-specific antigen identified with proteomic analysis in prostate cancer. PMID:33107155
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal. PMID:33106535
Oral Treatment With Ileal Spores Triggers Immunometabolic Shifts in Chicken Gut. PMID:33102558
Multiplexed gene expression analysis of HLA class II-associated podoconiosis implicates chronic immune activation in its pathogenesis. PMID:33099652
Functional network analysis reveals potential repurposing of β-blocker atenolol for pancreatic cancer therapy. PMID:33098056
Electronic-Cigarette Use Alters Nasal Mucosal Immune Response to Live-attenuated Influenza Virus. A Clinical Trial. PMID:33095645
Meta-analysis of Transcriptomic Data Reveals Pathophysiological Modules Involved with Atrial Fibrillation. PMID:33095430
Identification of Signatures of Selection by Whole-Genome Resequencing of a Chinese Native Pig. PMID:33093844
Predicting miRNA-disease associations using a hybrid feature representation in the heterogeneous network. PMID:33087118
Development of a genetic evaluation for hair shedding in American Angus cattle to improve thermotolerance. PMID:33087048
A method for estimating coherence of molecular mechanisms in major human disease and traits. PMID:33087046
Transcriptome analysis reveals potential immune function-related regulatory genes/pathways of female Lubo goat submandibular glands at different developmental stages. PMID:33083113
The Effect of Hedysarum multijugum Maxim.-Chuanxiong rhizoma Compound on Ischemic Stroke: A Research Based on Network and Experimental Pharmacology. PMID:33082911
TMT-Based Proteomic Analysis of Plasma from Children with Rolandic Epilepsy. PMID:33082886
Cancer Stem Cell Characteristics by Network Analysis of Transcriptome Data Stemness Indices in Breast Carcinoma. PMID:33082784
Neuroretinal-Derived Caveolin-1 Promotes Endotoxin-Induced Inflammation in the Murine Retina. PMID:33079993
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state. PMID:33077955
Quantifying the distribution of protein oligomerization degree reflects cellular information capacity. PMID:33077848
Predicted functional interactome of Caenorhabditis elegans and a web tool for the functional interpretation of differentially expressed genes. PMID:33076954
Implementation of homology based and non-homology based computational methods for the identification and annotation of orphan enzymes: using Mycobacterium tuberculosis H37Rv as a case study. PMID:33076816
Genetic Risk of Autism Spectrum Disorder in a Pakistani Population. PMID:33076578
Proteome analysis of Saccharomyces cerevisiae after methyl methane sulfonate (MMS) treatment. PMID:33072891
Significance of Tumor Mutation Burden in Immune Infiltration and Prognosis in Cutaneous Melanoma. PMID:33072607
Interactive Verification Analysis of Multiple Sequencing Data for Identifying Potential Biomarker of Lung Adenocarcinoma. PMID:33062704
Expression of collagen type 1 alpha 1 indicates lymph node metastasis and poor outcomes in squamous cell carcinomas of the lung. PMID:33062455
Exploration of the Potential Biomarkers of Papillary Thyroid Cancer (PTC) Based on RT2 Profiler PCR Arrays and Bioinformatics Analysis. PMID:33061614
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells. PMID:33057200
A strategy to incorporate prior knowledge into correlation network cutoff selection. PMID:33056991
Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip. PMID:33055246
LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies. PMID:33055242
Temporal Proteomic Profiling of SH-SY5Y Differentiation with Retinoic Acid Using FAIMS and Real-Time Searching. PMID:33054241
Lipid metabolism gene-wide profile and survival signature of lung adenocarcinoma. PMID:33050938
Integrating Single-Step GWAS and Bipartite Networks Reconstruction Provides Novel Insights into Yearling Weight and Carcass Traits in Hanwoo Beef Cattle. PMID:33050182
Identification of potential molecular pathways involved in prostate carcinogenesis in offspring exposed to maternal malnutrition. PMID:33049715
Micro RNA Targets in HIV Latency: Insights into Novel Layers of Latency Control. PMID:33045840
Assessment for prognostic value of differentially expressed genes in immune microenvironment of clear cell renal cell carcinoma. PMID:33042428
Chilling Stress Triggers VvAgo1-Mediated miRNA-Like RNA Biogenesis in Volvariella volvacea. PMID:33042047
Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer. PMID:33039466
Quantitative Proteomics Reveals the Beneficial Effects of Low Glucose on Neuronal Cell Survival in an in vitro Ischemic Penumbral Model. PMID:33033473
Comprehensive analysis of TPX2-related ceRNA network as prognostic biomarkers in lung adenocarcinoma. PMID:33029085
Integration of anatomy ontology data with protein-protein interaction networks improves the candidate gene prediction accuracy for anatomical entities. PMID:33028186
Identification of a new pseudogenes/lncRNAs-hsa-miR-26b-5p-COL12A1 competing endogenous RNA network associated with prognosis of pancreatic cancer using bioinformatics analysis. PMID:33027767
RNA oxidation in chromatin modification and DNA-damage response following exposure to formaldehyde. PMID:33024153
Mesenchymal stem cells alleviate LPS-induced acute lung injury by inhibiting the proinflammatory function of Ly6C+ CD8+ T cells. PMID:33024074
Identification of Parkinson's disease-related pathways and potential risk factors. PMID:33021140
Molecular characterization and functional annotation of a hypothetical protein (SCO0618) of Streptomyces coelicolor A3(2). PMID:33017872
Identification of TYROBP and C1QB as Two Novel Key Genes With Prognostic Value in Gastric Cancer by Network Analysis. PMID:33014868
NF-κB signaling induces inductive expression of the downstream molecules and IgD gene in the freshwater carp, Catla catla. PMID:33014688
Systematically Exploring the Antitumor Mechanisms of Core Chinese Herbs on Hepatocellular Carcinoma: A Computational Study. PMID:33014099
Phylogenetic Relationships and Potential Functional Attributes of the Genus Parapedobacter: A Member of Family Sphingobacteriaceae. PMID:33013721
Screening and Identification of Key Biomarkers in Acquired Lapatinib-Resistant Breast Cancer. PMID:33013420
Keratin 17 regulates nuclear morphology and chromatin organization. PMID:33008845
Genetic Variation and Autism: A Field Synopsis and Systematic Meta-Analysis. PMID:33007889
Association of tricellulin expression with poor colorectal cancer prognosis and metastasis. PMID:33000262
Nano-ellagic acid: inhibitory actions on aldose reductase and α-glucosidase in secondary complications of diabetes, strengthened by in silico docking studies. PMID:32999815
COL3A1, COL6A3, and SERPINH1 Are Related to Glucocorticoid-Induced Osteoporosis Occurrence According to Integrated Bioinformatics Analysis. PMID:32999266
Analysis of long noncoding RNA-associated competing endogenous RNA network in glucagon-like peptide-1 receptor agonist-mediated protection in β cells. PMID:32994866
Re-establishment of the epigenetic state and rescue of kinome deregulation in Ts65Dn mice upon treatment with green tea extract and environmental enrichment. PMID:32994493
Aberration of the modulatory functions of intronic microRNA hsa-miR-933 on its host gene ATF2 results in type II diabetes mellitus and neurodegenerative disease development. PMID:32993798
Comprehensive analysis of angiogenesis-related genes and pathways in early diabetic retinopathy. PMID:32993645
Herbal pair Huangqin-Baishao: mechanisms underlying inflammatory bowel disease by combined system pharmacology and cell experiment approach. PMID:32988394
Integrative Bioinformatics Analysis Reveals Potential Target Genes and TNFα Signaling Inhibition by Brazilin in Metastatic Breast Cancer Cells. PMID:32986377
Named Entity Recognition and Relation Detection for Biomedical Information Extraction. PMID:32984300
Transcriptomic Analyses of Myeloid-Derived Suppressor Cell Subsets in the Circulation of Colorectal Cancer Patients. PMID:32984004
Development and Validation of a Clinical Prognostic Model Based on Immune-Related Genes Expressed in Clear Cell Renal Cell Carcinoma. PMID:32983989
Cold Plasma Treatment of Sunflower Seeds Modulates Plant-Associated Microbiome and Stimulates Root and Lateral Organ Growth. PMID:32983218
Identification of FADS1 Through Common Gene Expression Profiles for Predicting Survival in Patients with Bladder Cancer. PMID:32982427
Proteomic Profiling Reveals Roles of Stress Response, Ca2+ Transient Dysregulation, and Novel Signaling Pathways in Alcohol-Induced Cardiotoxicity. PMID:32981093
Identification of Hub Genes and Key Pathways Associated with Peripheral T-cell Lymphoma. PMID:32980897
Transcriptomics-Based Drug Repurposing Approach Identifies Novel Drugs against Sorafenib-Resistant Hepatocellular Carcinoma. PMID:32977582
Integrated regulatory models for inference of subtype-specific susceptibilities in glioblastoma. PMID:32974985
Gaussian Embedding for Large-scale Gene Set Analysis. PMID:32968711
Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning. PMID:32967266
Unveiling molecular signatures of preeclampsia and gestational diabetes mellitus with multi-omics and innovative cheminformatics visualization tools. PMID:32966491
Molecular classification of the placebo effect in nausea. PMID:32966280
Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis. PMID:32963334
Bioinformatic screening for candidate biomarkers and their prognostic values in endometrial cancer. PMID:32962636
Multi-scale supervised clustering-based feature selection for tumor classification and identification of biomarkers and targets on genomic data. PMID:32962626
Modification of the Histone Landscape with JAK Inhibition in Myeloproliferative Neoplasms. PMID:32962027
miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis. PMID:32961796
Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment. PMID:32959892
Integrated meta-analysis, network pharmacology, and molecular docking to investigate the efficacy and potential pharmacological mechanism of Kai-Xin-San on Alzheimer's disease. PMID:32956608
FlaGs and webFlaGs: discovering novel biology through the analysis of gene neighbourhood conservation. PMID:32956448
Transcription factor expression defines subclasses of developing projection neurons highly similar to single-cell RNA-seq subtypes. PMID:32948690
Differential gene expression of tumor-infiltrating CD8+ T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis. PMID:32948653
Inhibition of DNA Repair Pathways and Induction of ROS Are Potential Mechanisms of Action of the Small Molecule Inhibitor BOLD-100 in Breast Cancer. PMID:32947941
Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development. PMID:32946788
Competing endogenous RNA network analysis for screening inflammation‑related long non‑coding RNAs for acute ischemic stroke. PMID:32945445
Upregulated lncRNA Pvt1 may be important for cardiac remodeling at the infarct border zone. PMID:32945428
The critical role of BAP1 mutation in the prognosis and treatment selection of kidney renal clear cell carcinoma. PMID:32944533
MicroRNA-221-3p is related to survival and promotes tumour progression in pancreatic cancer: a comprehensive study on functions and clinicopathological value. PMID:32943991
Activity-based protein profiling of rice (Oryza sativa L.) bran serine hydrolases. PMID:32938958
Molecular characteristics associated with ferroptosis in hepatocellular carcinoma progression. PMID:32936424
Epithelial-to-mesenchymal transition markers are differentially expressed in epithelial cancer cell lines after everolimus treatment. PMID:32934726
Elucidating potential molecular signatures through host-microbe interactions for reactive arthritis and inflammatory bowel disease using combinatorial approach. PMID:32934294
Global analysis of SBP gene family in Brachypodium distachyon reveals its association with spike development. PMID:32929136
Identification of MTHFD2 as a novel prognosis biomarker in esophageal carcinoma patients based on transcriptomic data and methylation profiling. PMID:32925794
Identification of genes and pathways associated with subchondral bone in osteoarthritis via bioinformatic analysis. PMID:32925767
The Immune Landscape and Prognostic Immune Key Genes Potentially Involved in Modulating Synaptic Functions in Prostate Cancer. PMID:32923385
Monocyte and Macrophage-Mediated Pathology and Protective Immunity During Schistosomiasis. PMID:32922381
Brain micro-architecture and disinhibition: a latent phenotyping study across 33 impulsive and compulsive behaviours. PMID:32919402
Immune expression profile identification in a group of proliferative verrucous leukoplakia patients: a pre-cancer niche for oral squamous cell carcinoma development. PMID:32918120
In silico functional prediction of hypothetical proteins from the core genome of Corynebacterium pseudotuberculosis biovar ovis. PMID:32913672
Genome-wide RNA-sequencing dataset reveals the prognostic value and potential molecular mechanisms of lncRNA in non-homologous end joining pathway 1 in early stage Pancreatic Ductal Adenocarcinoma. PMID:32913451
Temporal Quantitative Proteomics of mGluR-induced Protein Translation and Phosphorylation in Neurons. PMID:32912969
A Novel Mechanism for NF-κB-activation via IκB-aggregation: Implications for Hepatic Mallory-Denk-Body Induced Inflammation. PMID:32912968
Effect Sizes of Deletions and Duplications on Autism Risk Across the Genome. PMID:32911998
Bioinformatics Analysis of Key Genes and circRNA-miRNA-mRNA Regulatory Network in Gastric Cancer. PMID:32908877
Genetic variant rs2494938 of LRFN2 gene is associated with non-small cell lung cancer risk in North-Indian population. PMID:32904533
Identification of Immune-Related Prognostic Biomarkers Based on the Tumor Microenvironment in 20 Malignant Tumor Types With Poor Prognosis. PMID:32903590
Uncovering the Mechanisms of Cryptotanshinone as a Therapeutic Agent Against Hepatocellular Carcinoma. PMID:32903546
Association Analysis of Peripheral and CSF Biomarkers in Late Mild Cognitive Impairment. PMID:32903489
Long non‑coding RNA MEG3 suppresses epithelial‑to‑mesenchymal transition by inhibiting the PSAT1‑dependent GSK‑3β/Snail signaling pathway in esophageal squamous cell carcinoma. PMID:32901893
Network Rewiring: Physiological Consequences of Reciprocally Exchanging the Physical Locations and Growth-Phase-Dependent Expression Patterns of the Salmonella fis and dps Genes. PMID:32900812
Drug Vulnerabilities and Disease Prognosis Linked to the Stem Cell-Like Gene Expression Program Triggered by the RHO GTPase Activator VAV2 in Hyperplastic Keratinocytes and Head and Neck Cancer. PMID:32899210
Integrative Network Biology Framework Elucidates Molecular Mechanisms of SARS-CoV-2 Pathogenesis. PMID:32895641
Maternal oxycodone treatment causes pathophysiological changes in the mouse placenta. PMID:32891007
Active Packaging of Immobilized Zinc Oxide Nanoparticles Controls Campylobacter jejuni in Raw Chicken Meat. PMID:32887715
The differences of regulatory networks between papillary and anaplastic thyroid carcinoma: an integrative transcriptomics study. PMID:32887540
Whole-exome mutational landscape of metastasis in patient-derived hepatocellular carcinoma cells. PMID:32884992
LSTrAP-Crowd: prediction of novel components of bacterial ribosomes with crowd-sourced analysis of RNA sequencing data. PMID:32883264
MiR-489 aggravates H2O2-induced apoptosis of cardiomyocytes via inhibiting IGF1. PMID:32880387
Pathogenic impact of transcript isoform switching in 1,209 cancer samples covering 27 cancer types using an isoform-specific interaction network. PMID:32879328
Cigarillos Compromise the Mucosal Barrier and Protein Expression in Airway Epithelia. PMID:32877614
Jasmonate induced alternative splicing responses in Arabidopsis. PMID:32875268
Two-Player Game in a Complex Landscape: 26S Proteasome, PKA, and Intracellular Calcium Concentration Modulate Mammalian Sperm Capacitation by Creating an Integrated Dialogue-A Computational Analysis. PMID:32872422
The Acidic Stress Response of the Intracellular Pathogen Brucella melitensis: New Insights from a Comparative, Genome-Wide Transcriptome Analysis. PMID:32872264
m6A RNA modification modulates PI3K/Akt/mTOR signal pathway in Gastrointestinal Cancer. PMID:32863943
Identification of Therapeutic and Prognostic Biomarkers of Lamin C (LAMC) Family Members in Head and Neck Squamous Cell Carcinoma. PMID:32860673
Characterization of Kinase Expression Related to Increased Migration of PC-3M Cells Using Global Comparative Phosphoproteome Analysis. PMID:32859632
Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence. PMID:32857162
The fusiform gyrus exhibits an epigenetic signature for Alzheimer's disease. PMID:32854783
Transcriptomic Analysis of Chicken Lungs Infected With Avian and Bovine Pasteurella multocida Serotype A. PMID:32851030
Host-Defense Peptides Caerin 1.1 and 1.9 Stimulate TNF-Alpha-Dependent Apoptotic Signals in Human Cervical Cancer HeLa Cells. PMID:32850805
Genome-Wide Transcriptional Regulation of the Long Non-coding RNA Steroid Receptor RNA Activator in Human Erythroblasts. PMID:32849830
Identifying a Comprehensive ceRNA Network to Reveal Novel Targets for the Pathogenesis of Parkinson's Disease. PMID:32849243
Target Analysis and Mechanism of Podophyllotoxin in the Treatment of Triple-Negative Breast Cancer. PMID:32848800
Sperm Proteome after Interaction with Reproductive Fluids in Porcine: From the Ejaculation to the Fertilization Site. PMID:32842715
Comparative analyses of alphaviral RNA:Protein complexes reveals conserved host-pathogen interactions. PMID:32841293
A Pipeline for Integrated Theory and Data-Driven Modeling of Biomedical Data. PMID:32841121
Identification of differentially expressed genes between mucinous adenocarcinoma and other adenocarcinoma of colorectal cancer using bioinformatics analysis. PMID:32840168
Neurological manifestations of COVID-19: available evidences and a new paradigm. PMID:32839951
SARS-CoV-2-human protein-protein interaction network. PMID:32838020
Suppression of Dynamical Network Biomarker Signals at the Predisease State (Mibyou) before Metabolic Syndrome in Mice by a Traditional Japanese Medicine (Kampo Formula) Bofutsushosan. PMID:32831883
Sex differences in circulating proteins in heart failure with preserved ejection fraction. PMID:32831121
Hypoxia Predicts Poor Prognosis in Neuroblastoma Patients and Associates with Biological Mechanisms Involved in Telomerase Activation and Tumor Microenvironment Reprogramming. PMID:32825087
Comparative Analysis of Mouse Decidualization Models at the Molecular Level. PMID:32823685
A-to-I RNA editing in bacteria increases pathogenicity and tolerance to oxidative stress. PMID:32822429
Identification of Critical Pathways and Hub Genes in LanCL1-Overexpressed Prostate Cancer Cells. PMID:32821124
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells. PMID:32813135
Systematic characterization of the branch point binding protein, splicing factor 1, gene family in plant development and stress responses. PMID:32811430
A sparse Bayesian factor model for the construction of gene co-expression networks from single-cell RNA sequencing count data. PMID:32811424
Systems biology reveals reprogramming of the S-nitroso-proteome in the cortical and striatal regions of mice during aging process. PMID:32807865
Clinical, genomics and networking analyses of a high-altitude native American Ecuadorian patient with congenital insensitivity to pain with anhidrosis: a case report. PMID:32807182
Exploring the mechanism of Radix Rhei Et Rhizome intervention in intracerebral hemorrhage based on systematic pharmacology and proteomics strategy. PMID:32803256
Potential Molecular Mechanism of the NPPB Gene in Postischemic Heart Failure with and without T2DM. PMID:32802835
Comprehensive Analysis of a circRNA-miRNA-mRNA Network to Reveal Potential Inflammation-Related Targets for Gastric Adenocarcinoma. PMID:32801999
Highly multiplexed quantitative proteomic and phosphoproteomic analyses in vascular smooth muscle cell dedifferentiation. PMID:32800120
Premature Activation of Immune Transcription Programs in Autoimmune-Predisposed Mouse Embryonic Stem Cells and Blastocysts. PMID:32796510
Genome-wide identification and characterization of bHLH family genes from Ginkgo biloba. PMID:32792673
Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia. PMID:32792571
Serum Protein Profiling Reveals a Landscape of Inflammation and Immune Signaling in Early-stage COVID-19 Infection. PMID:32788344
To bloom once or more times: the reblooming mechanisms of Iris germanica revealed by transcriptome profiling. PMID:32787785
Using Micro- and Macro-Level Network Metrics Unveils Top Communicative Gene Modules in Psoriasis. PMID:32785106
Protein Expression Analysis of an In Vitro Murine Model of Prostate Cancer Progression: Towards Identification of High-Potential Therapeutic Targets. PMID:32784957
Applications of Proteomic Tools to Study Insect Vector-Plant Virus Interactions. PMID:32784674
Identification of transcriptomic markers for developing idiopathic pulmonary fibrosis: an integrative analysis of gene expression profiles. PMID:32782692
Functional Molecular Network Analysis Enables Prediction of Response to Vedolizumab Therapy in Anti-TNF Refractory IBD Patients. PMID:32776006
Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population. PMID:32775599
Identification of CD38 as a potential biomarker in skin cutaneous melanoma using bioinformatics analysis. PMID:32774485
Transgelin interacts with PARP1 in human colon cancer cells. PMID:32774160
Bioinformatics analysis of differentially expressed genes in subchondral bone in early experimental osteoarthritis using microarray data. PMID:32771051
Identification of novel biomarkers and small-molecule compounds for nasopharyngeal carcinoma with metastasis. PMID:32769887
Proteomic resolution of IGFN1 complexes reveals a functional interaction with the actin nucleating protein COBL. PMID:32768501
Single-Sample Node Entropy for Molecular Transition in Pre-deterioration Stage of Cancer. PMID:32766227
The regulatory genome constrains protein sequence evolution: implications for the search for disease-associated genes. PMID:32765967
Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model. PMID:32762937
Genome-wide methylation patterns predict clinical benefit of immunotherapy in lung cancer. PMID:32762727
Plasma proteomic profile of frailty. PMID:32762010
Predicting new drug indications for prostate cancer: The integration of an in silico proteochemometric network pharmacology platform with patient-derived primary prostate cells. PMID:32761925
FLUTE: Fast and reliable knowledge retrieval from biomedical literature. PMID:32761077
Genomic Variation and Arsenic Tolerance Emerged as Niche Specific Adaptations by Different Exiguobacterium Strains Isolated From the Extreme Salar de Huasco Environment in Chilean - Altiplano. PMID:32760381
Identification of epigenetic interactions between microRNA and DNA methylation associated with polycystic ovarian syndrome. PMID:32759991
Comparative gene expression profiling between optic nerve and spinal cord injury in Xenopus laevis reveals a core set of genes inherent in successful regeneration of vertebrate central nervous system axons. PMID:32758133
Levels of endocrine-disrupting chemicals are associated with changes in the peri-pubertal epigenome. PMID:32755991
Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma. PMID:32755597
The Dysregulation and Prognostic Analysis of STRIPAK Complex Across Cancers. PMID:32754603
An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease. PMID:32753478
Molecular Evolution and Characterization of Fish Stathmin Genes. PMID:32752168
The composition and turnover of the Arabidopsis thaliana 80S cytosolic ribosome. PMID:32744327
Identification of key genes of human bone marrow stromal cells adipogenesis at an early stage. PMID:32742785
Aberrant methylation and microRNA-target regulation are associated with downregulated NEURL1B: a diagnostic and prognostic target in colon cancer. PMID:32742189
Concomitant DNA methylation and transcriptome signatures define epidermal responses to acute solar UV radiation. PMID:32737342
Identification of Prognostic Biomarkers Associated with Cancer Stem Cell Features in Prostate Adenocarcinoma. PMID:32735556
Dietary supplementation with a microencapsulated blend of organic acids and botanicals alters the kinome in the ileum and jejunum of Gallus gallus. PMID:32730335
Proteomic responses to progressive dehydration stress in leaves of chickpea seedlings. PMID:32727351
Human Respiratory Syncytial Virus-Induced Immune Signature of Infection Revealed by Transcriptome Analysis of Clinical Pediatric Nasopharyngeal Swab Samples. PMID:32726438
Prediction of the Receptorome for the Human-Infecting Virome. PMID:32725480
Crosstalk between EP2 and PPARα Modulates Hypoxic Signaling and Myopia Development in Guinea Pigs. PMID:32725213
Identification and validation of tumor microenvironment-related genes of prognostic value in lung adenocarcinoma. PMID:32724420
In-Depth Bioinformatic Analyses of Nidovirales Including Human SARS-CoV-2, SARS-CoV, MERS-CoV Viruses Suggest Important Roles of Non-canonical Nucleic Acid Structures in Their Lifecycles. PMID:32719673
Four pleiotropic loci associated with fat mass and lean mass. PMID:32719433
A novel predictive model incorporating immune-related gene signatures for overall survival in melanoma patients. PMID:32719391
Insights into the skin of caecilian amphibians from gene expression profiles. PMID:32718305
Network Approaches for Dissecting the Immune System. PMID:32717640
Identification of Differentially Expressed Genes and miRNAs Associated with Esophageal Squamous Cell Carcinoma by Integrated Analysis of Microarray Data. PMID:32714975
p.Gln318X and p.Val281Leu as the Major Variants of CYP21A2 Gene in Children with Idiopathic Premature Pubarche. PMID:32714392
Integrative Network Biology Framework Elucidates Molecular Mechanisms of SARS-CoV-2 Pathogenesis. PMID:32714115
Lipid Metabolism is the common pathologic mechanism between Type 2 Diabetes Mellitus and Parkinson's disease. PMID:32714075
Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer's disease. PMID:32711556
Quantitative proteomics reveals the regulatory networks of circular RNA BTBD7_hsa_circ_0000563 in human coronary artery. PMID:32710445
Pre-Treatment Mutational and Transcriptomic Landscape of Responding Metastatic Melanoma Patients to Anti-PD1 Immunotherapy. PMID:32708981
TCGA Pan-Cancer Genomic Analysis of Alternative Lengthening of Telomeres (ALT) Related Genes. PMID:32708340
Whole-Exome Sequencing of Patients With Posterior Segment Uveitis. PMID:32707200
Cross‑validation of genes potentially associated with neoadjuvant chemotherapy and platinum‑based chemoresistance in epithelial ovarian carcinoma. PMID:32705213
Identification of potential markers for type 2 diabetes mellitus via bioinformatics analysis. PMID:32705173
Bioinformatics analysis of gene expression profile of serous ovarian carcinomas to screen key genes and pathways. PMID:32693821
Complex-centric proteome profiling by SEC-SWATH-MS for the parallel detection of hundreds of protein complexes. PMID:32690956
Footprint-based functional analysis of multiomic data. PMID:32685770
Effect of BRCA1 on the Concurrent Chemoradiotherapy Resistance of Cervical Squamous Cell Carcinoma Based on Transcriptome Sequencing Analysis. PMID:32685473
Rapamycin-based graft-versus-host disease prophylaxis increases the immunosuppressivity of myeloid-derived suppressor cells without affecting T cells and anti-tumor cytotoxicity. PMID:32681646
Protein-Protein interactions uncover candidate 'core genes' within omnigenic disease networks. PMID:32678846
High fat diet causes distinct aberrations in the testicular proteome. PMID:32678325
A novel serum miRNA-pair classifier for diagnosis of sarcoma. PMID:32673360
Human bone marrow stem/stromal cell osteogenesis is regulated via mechanically activated osteocyte-derived extracellular vesicles. PMID:32672416
Association of CXCL13 and Immune Cell Infiltration Signature in Clear Cell Renal Cell Carcinoma. PMID:32669964
Leucine-Rich Diet Modulates the Metabolomic and Proteomic Profile of Skeletal Muscle during Cancer Cachexia. PMID:32668598
H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts. PMID:32664951
Hsa_circ_0002320: a novel clinical biomarker for colorectal cancer prognosis. PMID:32664176
Gene Loss Predictably Drives Evolutionary Adaptation. PMID:32658971
A trafficome-wide RNAi screen reveals deployment of early and late secretory host proteins and the entire late endo-/lysosomal vesicle fusion machinery by intracellular Salmonella. PMID:32658937
Combining phenome-driven drug-target interaction prediction with patients' electronic health records-based clinical corroboration toward drug discovery. PMID:32657406
GLIDE: combining local methods and diffusion state embeddings to predict missing interactions in biological networks. PMID:32657369
Paternal Resistance Training Modulates Calcaneal Tendon Proteome in the Offspring Exposed to High-Fat Diet. PMID:32656202
Identification of Differentially Expressed Hematopoiesis-associated Genes in Term Low Birth Weight Newborns by Systems Genomics Approach. PMID:32655286
Hepatoprotective effects of Hovenia dulcis seeds against alcoholic liver injury and related mechanisms investigated via network pharmacology. PMID:32655267
Multi-locus interactions and the build-up of reproductive isolation. PMID:32654649
Up-regulation of autophagy by low concentration of salicylic acid delays methyl jasmonate-induced leaf senescence. PMID:32651431
Loss of miR-101-3p Promotes Transmigration of Metastatic Breast Cancer Cells through the Brain Endothelium by Inducing COX-2/MMP1 Signaling. PMID:32645833
Exploring the Molecular Mechanisms of Pterygium by Constructing lncRNA-miRNA-mRNA Regulatory Network. PMID:32645133
Comparative proteomic analysis of human mesenchymal stromal cell behavior on calcium phosphate ceramics with different osteoinductive potential. PMID:32642640
Identification of key genes for esophageal squamous cell carcinoma via integrated bioinformatics analysis and experimental confirmation. PMID:32642240
Identification key genes, key miRNAs and key transcription factors of lung adenocarcinoma. PMID:32642095
Constructing knowledge graphs and their biomedical applications. PMID:32637040
Mechanism of Astragalus membranaceus in the treatment of laryngeal cancer based on gene co-expression network and molecular docking. PMID:32636440
Bioinformatics analysis of high-throughput data to validate potential novel biomarkers and small molecule drugs for glioblastoma multiforme. PMID:32634050
Gene Regulatory Network Guided Investigations and Engineering of Storage Root Development in Root Crops. PMID:32625220
Prediabetes Induced by a Single Autoimmune B Cell Clone. PMID:32625203
Disease-related cellular protein networks differentially affected under different EGFR mutations in lung adenocarcinoma. PMID:32616892
PODXL might be a new prognostic biomarker in various cancers: a meta-analysis and sequential verification with TCGA datasets. PMID:32615943
Novel candidate drugs in anti-tumor necrosis factor refractory Crohn's diseases: in silico study for drug repositioning. PMID:32612148
Concise Polygenic Models for Cancer-Specific Identification of Drug-Sensitive Tumors from Their Multi-Omics Profiles. PMID:32604779
Hub Proteins Involved in RAW 264.7 Macrophages Exposed to Direct Current Electric Field. PMID:32599940
Integrated Analysis of a Gene Correlation Network Identifies Critical Regulation of Fibrosis by lncRNAs and TFs in Idiopathic Pulmonary Fibrosis. PMID:32596346
Identification of miRNA-mRNA-TFs Regulatory Network and Crucial Pathways Involved in Tetralogy of Fallot. PMID:32595699
Integration of transcriptomic profile of SARS-CoV-2 infected normal human bronchial epithelial cells with metabolic and protein-protein interaction networks. PMID:32595353
Key genes associated with non-alcoholic fatty liver disease and acute myocardial infarction. PMID:32594092
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation. PMID:32591500
Identification of prognostic risk factors for pancreatic cancer using bioinformatics analysis. PMID:32587798
Differential methylation and expression of genes in the hypoxia-inducible factor 1 signaling pathway are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors and with preclinical models of chemotherapy-induced neuropathic pain. PMID:32586194
Identification of a Profile of Neutrophil-Derived Granule Proteins in the Surface of Gold Nanoparticles after Their Interaction with Human Breast Cancer Sera. PMID:32586001
Minichromosome maintenance 6 complex component identified by bioinformatics analysis and experimental validation in esophageal squamous cell carcinoma. PMID:32583000
Dysregulated m6A-Related Regulators Are Associated With Tumor Metastasis and Poor Prognosis in Osteosarcoma. PMID:32582536
Use of Dual RNA-seq for Systems Biology Analysis of Zea mays and Aspergillus flavus Interaction. PMID:32582038
Exploring TCGA database for identification of potential prognostic genes in stomach adenocarcinoma. PMID:32581654
Sex Differences in Gene Expression and Regulatory Networks across 29 Human Tissues. PMID:32579922
Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1. PMID:32574189
Exploring Mechanism of Key Chinese Herbal Medicine on Breast Cancer by Data Mining and Network Pharmacology Methods. PMID:32572780
Immune-related genes in tumor-specific CD4+ and CD8+ T cells in colon cancer. PMID:32571262
Reducing the nicotine content of tobacco by grafting with eggplant. PMID:32571218
Bioinformatics analysis of different candidate genes involved in hepatocellular carcinoma induced by HepG2 cells or tumor cells of patients. PMID:32567431
Identification of Key Genes and Long Noncoding RNA-Associated Competing Endogenous RNA (ceRNA) Networks in Early-Onset Preeclampsia. PMID:32566660
PPARγ: the dominant regulator among PPARs in dry eye lacrimal gland and diabetic lacrimal gland. PMID:32566495
Genome-wide identification and expression analysis of the Dof gene family under drought stress in tea (Camellia sinensis). PMID:32566398
Distinct diagnostic and prognostic values of γ-aminobutyric acid type A receptor family genes in patients with colon adenocarcinoma. PMID:32565954
YRDC is upregulated in non-small cell lung cancer and promotes cell proliferation by decreasing cell apoptosis. PMID:32565932
CUL1-Mediated Organelle Fission Pathway Inhibits the Development of Chronic Obstructive Pulmonary Disease. PMID:32565880
Upregulation of cGMP-dependent Protein Kinase (PRKG1) in the Development of Adolescent Idiopathic Scoliosis. PMID:32558266
Sequencing of RNA in single cells reveals a distinct transcriptome signature of hematopoiesis in GATA2 deficiency. PMID:32556286
Patient genetics is linked to chronic wound microbiome composition and healing. PMID:32555671
Identification of the key genes and microRNAs in adult acute myeloid leukemia with FLT3 mutation by bioinformatics analysis. PMID:32547322
Identification of Hub Genes in Type 2 Diabetes Mellitus Using Bioinformatics Analysis. PMID:32547141
Insights from the in silico structural, functional and phylogenetic characterization of canine lysyl oxidase protein. PMID:32542505
DNA methylation-based diagnostic and prognostic biomarkers of nasopharyngeal carcinoma patients. PMID:32541515
Clinical significance and biological mechanisms of glutathione S-transferase mu gene family in colon adenocarcinoma. PMID:32539715
Ezrin is essential for the entry of Japanese encephalitis virus into the human brain microvascular endothelial cells. PMID:32538298
Orthogonal Proteomic Platforms and Their Implications for the Stable Classification of High-Grade Serous Ovarian Cancer Subtypes. PMID:32534439
Deep learning in mental health outcome research: a scoping review. PMID:32532967
Revealing the key point of the temperature stress response of Arthrospira platensis C1 at the interconnection of C- and N- metabolism by proteome analyses and PPI networking. PMID:32532219
Transcriptome Profiling Reveals Novel Candidate Genes Related to Hippocampal Dysfunction in SREBP-1c Knockout Mice. PMID:32531902
Aortic Valve Regurgitation: Pathophysiology and Implications for Surgical Intervention in the Era of TAVR. PMID:32529168
Dynamics of Gene Co-expression Networks in Time-Series Data: A Case Study in Drosophila melanogaster Embryogenesis. PMID:32528531
Identification and Validation of Potential Biomarkers and Their Functions in Acute Kidney Injury. PMID:32528518
Ablation of the miRNA Cluster 24 Has Profound Effects on Extracellular Matrix Protein Abundance in Cartilage. PMID:32526967
A blood RNA transcript signature for TB exposure in household contacts. PMID:32517725
Omics Integration Analyses Reveal the Early Evolution of Malignancy in Breast Cancer. PMID:32512721
CD56 regulates human NK cell cytotoxicity through Pyk2. PMID:32510326
Identifying multiple collagen gene family members as potential gastric cancer biomarkers using integrated bioinformatics analysis. PMID:32509452
Identification of immune-related biomarkers associated with tumorigenesis and prognosis in cutaneous melanoma patients. PMID:32508531
Identification of potential candidate genes and pathways in atrioventricular nodal reentry tachycardia by whole-exome sequencing. PMID:32508047
Tamoxifen induces fatty liver disease in breast cancer through the MAPK8/FoxO pathway. PMID:32508033
Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics. PMID:32501498
RNA-Seq Analyses Reveal That Endothelial Activation and Fibrosis Are Induced Early and Progressively by Besnoitia besnoiti Host Cell Invasion and Proliferation. PMID:32500038
Expression profiling of small intestinal neuroendocrine tumors identified pathways and gene networks linked to tumorigenesis and metastasis. PMID:32496505
Excessive Homeostatic Gain in Spinal Motoneurons in a Mouse Model of Amyotrophic Lateral Sclerosis. PMID:32493926
Network pharmacology to dissect the mechanisms of Yinlai Decoction for pneumonia. PMID:32493296
Transplantation Induces Profound Changes in the Transcriptional Asset of Hematopoietic Stem Cells: Identification of Specific Signatures Using Machine Learning Techniques. PMID:32492887
Longitudinal Analysis of Gene Expression Changes During Cervical Carcinogenesis Reveals Potential Therapeutic Targets. PMID:32489245
Genomic analyses of early responses to radiation inglioblastoma reveal new alterations at transcription,splicing, and translation levels. PMID:32488114
Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide. PMID:32486366
Scoring functions for drug-effect similarity. PMID:32484516
A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface. PMID:32482893
Possible key microRNAs and corresponding molecular mechanisms for atrial fibrillation. PMID:32478689
Whole-exome sequencing and genome-wide association studies identify novel sarcopenia risk genes in Han Chinese. PMID:32478482
Feeding of yeast cell wall extracts during a necrotic enteritis challenge enhances cell growth, survival and immune signaling in the jejunum of broiler chickens. PMID:32475430
Molecular Choreography of Acute Exercise. PMID:32470399
Bioinformatics analysis of the network of histone H3 lysine 9 trimethylation in acute myeloid leukaemia. PMID:32468066
Identification of potential crucial genes and molecular mechanisms in glioblastoma multiforme by bioinformatics analysis. PMID:32467990
Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions. PMID:32463358
Questing functions and structures of hypothetical proteins from Campylobacter jejuni: a computer-aided approach. PMID:32458979
Trioxolone Methyl, a Novel Cyano Enone-Bearing 18βH-Glycyrrhetinic Acid Derivative, Ameliorates Dextran Sulphate Sodium-Induced Colitis in Mice. PMID:32455822
Paternal Resistance Training Induced Modifications in the Left Ventricle Proteome Independent of Offspring Diet. PMID:32454941
Network Pharmacology-Based Approach to Investigate the Mechanisms of Mahai Capsules in the Treatment of Cardiovascular Diseases. PMID:32454875
An Analysis of the Anti-Neuropathic Effects of Qi She Pill Based on Network Pharmacology. PMID:32454869
MiR-1908/EXO1 and MiR-203a/FOS, regulated by scd1, are associated with fracture risk and bone health in postmenopausal diabetic women. PMID:32454462
Proteomics of intracellular freezing survival. PMID:32453791
Activin-mediated alterations of the fibroblast transcriptome and matrisome control the biomechanical properties of skin wounds. PMID:32451392
Regulation of gene expression by MF63, a selective inhibitor of microsomal PGE synthase 1 (mPGES1) in human osteoarthritic chondrocytes. PMID:32449517
Network Pharmacology to Uncover the Molecular Mechanisms of Action of LeiGongTeng for the Treatment of Nasopharyngeal Carcinoma. PMID:32448862
GSEA-assisted gene signatures valid for combinations of prognostic markers in PCNSL. PMID:32439996
The microbiome as a biosensor: functional profiles elucidate hidden stress in hosts. PMID:32438915
Examining Short-Term Responses to a Long-Term Problem: RNA-Seq Analyses of Iron Deficiency Chlorosis Tolerant Soybean. PMID:32438745
Altered mucins and aquaporins indicate dry eye outcome in patients undergoing Vitreo-retinal surgery. PMID:32437405
Exploring the mechanism of Shengmai Yin for coronary heart disease based on systematic pharmacology and chemoinformatics. PMID:32436944
Multi-omic signatures identify pan-cancer classes of tumors beyond tissue of origin. PMID:32433524
NetConfer: a web application for comparative analysis of multiple biological networks. PMID:32430035
Harnessing Gene Expression Profiles for the Identification of Ex Vivo Drug Response Genes in Pediatric Acute Myeloid Leukemia. PMID:32429253
Novel 3'-Substituted-1',2',4'-Oxadiazole Derivatives of 18βH-Glycyrrhetinic Acid and Their O-Acylated Amidoximes: Synthesis and Evaluation of Antitumor and Anti-Inflammatory Potential In Vitro and In Vivo. PMID:32429154
Sex Differences in Biological Processes and Nitrergic Signaling in Mouse Brain. PMID:32429146
Heterogeneities of Site-Specific N-Glycosylation in HCC Tumors With Low and High AFP Concentrations. PMID:32426269
Post-translational Modification Crosstalk and Hotspots in Sirtuin Interactors Implicated in Cardiovascular Diseases. PMID:32425973
Split-TurboID enables contact-dependent proximity labeling in cells. PMID:32424107
Identification of potential novel differentially-expressed genes and their role in invasion and migration in renal cell carcinoma. PMID:32420905
Screening and Identification of Differentially Expressed Genes Expressed among Left and Right Colon Adenocarcinoma. PMID:32420374
Immune-profiling of ZIKV-infected patients identifies a distinct function of plasmacytoid dendritic cells for immune cross-regulation. PMID:32415086
Association between SNAP25 and human glioblastoma multiform: a comprehensive bioinformatic analysis. PMID:32412599
SDN2GO: An Integrated Deep Learning Model for Protein Function Prediction. PMID:32411695
Prioritizing Cancer Genes Based on an Improved Random Walk Method. PMID:32411180
Leveraging Prior Knowledge to Recover Characteristic Immune Regulatory Motifs in Gulf War Illness. PMID:32411011
Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells. PMID:32410854
PaccMann: a web service for interpretable anticancer compound sensitivity prediction. PMID:32402082
Zeb1 represses TCR signaling, promotes the proliferation of T cell progenitors and is essential for NK1.1+ T cell development. PMID:32398809
Identification of a six-gene signature associated with tumor mutation burden for predicting prognosis in patients with invasive breast carcinoma. PMID:32395497
Yeast-Based Genetic Interaction Analysis of Human Kinome. PMID:32392905
Elevated mRNA expression levels of DLGAP5 are associated with poor prognosis in breast cancer. PMID:32391106
Altered protein levels in bone marrow lesions of hip osteoarthritis: Analysis by proteomics and multiplex immunoassays. PMID:32383346
The Role of Overexpressed Apolipoprotein AV in Insulin-Resistant Hepatocytes. PMID:32382544
A putative competing endogenous RNA network in cisplatin-resistant lung adenocarcinoma cells identifying potentially rewarding research targets. PMID:32382346
Systematic Elucidation of the Potential Mechanisms of Core Chinese Materia Medicas in Treating Liver Cancer Based on Network Pharmacology. PMID:32382293
Additive and mostly adaptive plastic responses of gene expression to multiple stress in Tribolium castaneum. PMID:32379753
Comparison of a human neuronal model proteome upon Japanese encephalitis or West Nile Virus infection and potential role of mosquito saliva in neuropathogenesis. PMID:32374750
Comprehensive analysis of Translationally Controlled Tumor Protein (TCTP) provides insights for lineage-specific evolution and functional divergence. PMID:32374732
Identifying Shared Risk Genes for Asthma, Hay Fever, and Eczema by Multi-Trait and Multiomic Association Analyses. PMID:32373153
Phenylpyrazalopyrimidines as Tyrosine Kinase Inhibitors: Synthesis, Antiproliferative Activity, and Molecular Simulations. PMID:32370213
Identification of crucial aberrantly methylated and differentially expressed genes related to cervical cancer using an integrated bioinformatics analysis. PMID:32368784
Evaluation of the proteomic profiles of ejaculated spermatozoa from Saanen bucks ( Capra hircus ). PMID:32368270
Coagulopathy signature precedes and predicts severity of end-organ heat stroke pathology in a mouse model. PMID:32367690
Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31. PMID:32366252
Exomes of Ductal Luminal Breast Cancer Patients from Southwest Colombia: Gene Mutational Profile and Related Expression Alterations. PMID:32365829
The Hippo Pathway Transducers YAP1/TEAD Induce Acquired Resistance to Trastuzumab in HER2-Positive Breast Cancer. PMID:32365528
MicroRNA-100 Enhances Autophagy and Suppresses Migration and Invasion of Renal Cell Carcinoma Cells via Disruption of NOX4-Dependent mTOR Pathway. PMID:32356935
Identification of exosomal miRNAs associated with the anthracycline-induced liver injury in postoperative breast cancer patients by small RNA sequencing. PMID:32355577
Promising diagnostic and prognostic value of six genes in human hepatocellular carcinoma. PMID:32355538
Comprehensive analysis of the SLC16A gene family in pancreatic cancer via integrated bioinformatics. PMID:32355273
In Silico Analysis of a Highly Mutated Gene in Cancer Provides Insight into Abnormal mRNA Splicing: Splicing Factor 3B Subunit 1K700E Mutant. PMID:32354150
Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1). PMID:32350110
WRKY genes family study reveals tissue-specific and stress-responsive TFs in wild potato species. PMID:32346026
Contribution of common and rare damaging variants in familial forms of bipolar disorder and phenotypic outcome. PMID:32345981
Overcoming hypoxia-induced functional suppression of NK cells. PMID:32345623
An Improved Phenotype-Driven Tool for Rare Mendelian Variant Prioritization: Benchmarking Exomiser on Real Patient Whole-Exome Data. PMID:32340307
Identification of Potential Biomarkers for Thyroid Cancer Using Bioinformatics Strategy: A Study Based on GEO Datasets. PMID:32337286
Sequential Interferon β-Cisplatin Treatment Enhances the Surface Exposure of Calreticulin in Cancer Cells via an Interferon Regulatory Factor 1-Dependent Manner. PMID:32326356
Knockdown of UTX/KDM6A Enriches Precursor Cell Populations in Urothelial Cell Cultures and Cell Lines. PMID:32326336
Expression based biomarkers and models to classify early and late-stage samples of Papillary Thyroid Carcinoma. PMID:32324757
Alternative proteins are functional regulators in cell reprogramming by PKA activation. PMID:32324228
ZWINT: A potential therapeutic biomarker in patients with glioblastoma correlates with cell proliferation and invasion. PMID:32323832
Profiling of subcellular EGFR interactome reveals hnRNP A3 modulates nuclear EGFR localization. PMID:32321917
TMSB10 acts as a biomarker and promotes progression of clear cell renal cell carcinoma. PMID:32319572
Differential expression of nuclear genes encoding mitochondrial proteins from urban and rural populations in Morocco. PMID:32319023
The novel E. coli cell division protein, YtfB, plays a role in eukaryotic cell adhesion. PMID:32317661
Association of common variation in ADD3 and GPC1 with biliary atresia susceptibility. PMID:32315284
PDZ Domains as Drug Targets. PMID:32313833
Bioinformatics analysis and verification of gene targets for benign tracheal stenosis. PMID:32309912
Screening TCGA database for prognostic genes in lower grade glioma microenvironment. PMID:32309356
ZGRF1 Is Associated with Poor Prognosis in Triple-Negative Breast Cancer and Promotes Cancer Stemness Based on Bioinformatics. PMID:32308418
Molecular networks in Network Medicine: Development and applications. PMID:32307915
Haploinsufficiency of X-linked intellectual disability gene CASK induces post-transcriptional changes in synaptic and cellular metabolic pathways. PMID:32305418
POLE2 Serves as a Prognostic Biomarker and Is Associated with Immune Infiltration in Squamous Cell Lung Cancer. PMID:32304567
G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules. PMID:32302571
Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity. PMID:32300166
Drug-Target Interaction Network Analysis of Gene-Phenotype Connectivity Maintained by Genistein. PMID:32298608
The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10. PMID:32293333
The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts. PMID:32293249
Revealing Dynamic Protein Acetylation across Subcellular Compartments. PMID:32290654
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway. PMID:32286267
CDK1-PLK1/SGOL2/ANLN pathway mediating abnormal cell division in cell cycle may be a critical process in hepatocellular carcinoma. PMID:32275843
Network modeling of single-cell omics data: challenges, opportunities, and progresses. PMID:32270049
Noncoding regions underpin avian bill shape diversification at macroevolutionary scales. PMID:32269134
Evaluation of the Prognostic Value of STEAP1 in Lung Adenocarcinoma and Insights Into Its Potential Molecular Pathways via Bioinformatic Analysis. PMID:32265985
Identification of Co-expressed Genes Between Atrial Fibrillation and Stroke. PMID:32265825
A comprehensive analysis of sialolith proteins and the clinical implications. PMID:32265614
Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patients. PMID:32264938
Identification of key genes and pathways affected in epicardial adipose tissue from patients with coronary artery disease by integrated bioinformatics analysis. PMID:32257639
Comprehensive gene and pathway analysis of cervical cancer progression. PMID:32256826
MicroRNA-1202 plays a vital role in osteoarthritis via KCNQ1OT1 has-miR-1202-ETS1 regulatory pathway. PMID:32252801
Identification of Genes with Prognostic Value in the Breast Cancer Microenvironment Using Bioinformatics Analysis. PMID:32251269
Exploring immune-related genes with prognostic value in microenvironment of breast cancer from TCGA database. PMID:32243373
The landscape of alternative splicing in HIV-1 infected CD4 T-cells. PMID:32241262
Mining TCGA database for tumor mutation burden and their clinical significance in bladder cancer. PMID:32239176
Natural-Killer-Derived Extracellular Vesicles: Immune Sensors and Interactors. PMID:32231660
Screening and Identification of Potential Biomarkers for Hepatocellular Carcinoma: An Analysis of TCGA Database and Clinical Validation. PMID:32231440
Identification of novel biomarkers in ischemic stroke: a genome-wide integrated analysis. PMID:32228489
Transcriptome profiling of non-climacteric 'yellow' melon during ripening: insights on sugar metabolism. PMID:32228445
Transcriptional analyses of two soybean cultivars under salt stress. PMID:32227253
Alterations in Immune-Related Genes as Potential Marker of Prognosis in Breast Cancer. PMID:32226776
Potential therapeutic targets of the nuclear division cycle 80 (NDC80) complexes genes in lung adenocarcinoma. PMID:32226507
Effect of nicastrin on hepatocellular carcinoma proliferation and apoptosis through PI3K/AKT signalling pathway modulation. PMID:32226312
Identification of hub genes associated with outcome of clear cell renal cell carcinoma. PMID:32218839
Bioinformatics Studies Provide Insight into Possible Target and Mechanisms of Action of Nobiletin against Cancer Stem Cells. PMID:32212785
LncRNAs Predicted to Interfere With the Gene Regulation Activity of miR-637 and miR-196a-5p in GBM. PMID:32211330
In silico Metabolic Pathway Analysis Identifying Target Against Leishmaniasis - A Kinetic Modeling Approach. PMID:32211028
Cellular processes involved in lung cancer cells exposed to direct current electric field. PMID:32210363
OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine. PMID:32210335
Secreted Phosphoprotein 1 (SPP1) and Fibronectin 1 (FN1) Are Associated with Progression and Prognosis of Esophageal Cancer as Identified by Integrated Expression Profiles Analysis. PMID:32208405
Understanding of Zaire ebolavirus-human protein interaction for drug repurposing. PMID:32206696
Deep phosphoproteome analysis of Schistosoma mansoni leads development of a kinomic array that highlights sex-biased differences in adult worm protein phosphorylation. PMID:32203512
Comprehensive bioinformatic analysis of Wnt1 and Wnt1-associated diseases. PMID:32201670
Role of the ERO1-PDI interaction in oxidative protein folding and disease. PMID:32201313
Sputum and blood transcriptomics characterisation of the inhaled PDE4 inhibitor CHF6001 on top of triple therapy in patients with chronic bronchitis. PMID:32197620
Proteomic signatures of in vivo muscle oxidative capacity in healthy adults. PMID:32196924
Expression of SREBP2 and cholesterol metabolism related genes in TCGA glioma cohorts. PMID:32195924
The Identification of Key Gene Expression Signature and Biological Pathways in Metastatic Renal Cell Carcinoma. PMID:32194783
Biglycan as a potential diagnostic and prognostic biomarker in multiple human cancers. PMID:32194659
Repositioning of Hypoglycemic Drug Linagliptin for Cancer Treatment. PMID:32194417
Network-based identification of signature genes KLF6 and SPOCK1 associated with oral submucous fibrosis. PMID:32190310
GSTM1 and GSTT1 genetic polymorphisms and their association with antituberculosis drug-induced liver injury. PMID:32190303
Immune-related prognosis biomarkers associated with osteosarcoma microenvironment. PMID:32190007
A Gene-Set Enrichment and Protein-Protein Interaction Network-Based GWAS with Regulatory SNPs Identifies Candidate Genes and Pathways Associated with Carcass Traits in Hanwoo Cattle. PMID:32188084
High TXLNA Expression Predicts Favourable Outcome for Pancreatic Adenocarcinoma Patients. PMID:32185195
EXP2SL: A Machine Learning Framework for Cell-Line-Specific Synthetic Lethality Prediction. PMID:32184722
Deoxynivalenol Induces Inflammation in IPEC-J2 Cells by Activating P38 Mapk And Erk1/2. PMID:32183221
Heat Stress Impairs the Physiological Responses and Regulates Genes Coding for Extracellular Exosomal Proteins in Rat. PMID:32183190
Comparative analysis of the human serine hydrolase OVCA2 to the model serine hydrolase homolog FSH1 from S. cerevisiae. PMID:32182256
Multiplexed Phosphoproteomic Study of Brain in Patients with Alzheimer's Disease and Age-Matched Cognitively Healthy Controls. PMID:32182160
Design of a Functionalized Metal-Organic Framework System for Enhanced Targeted Delivery to Mitochondria. PMID:32182066
In-depth proteome analysis of more than 12,500 proteins in buffalo mammary epithelial cell line identifies protein signatures for active proliferation and lactation. PMID:32179766
Large-scale Identification and Time-course Quantification of Ubiquitylation Events During Maize Seedling De-etiolation. PMID:32179194
The conserved DNMT1-dependent methylation regions in human cells are vulnerable to neurotoxicant rotenone exposure. PMID:32178731
Integrated miRNA/mRNA Counter-Expression Analysis Highlights Oxidative Stress-Related Genes CCR7 and FOXO1 as Blood Markers of Coronary Arterial Disease. PMID:32178422
Identification of aberrantly methylated differentially expressed genes and associated pathways in endometrial cancer using integrated bioinformatic analysis. PMID:32170852
Genes associated with inflammation may serve as biomarkers for the diagnosis of coronary artery disease and ischaemic stroke. PMID:32164735
Non-lethal exposure to H2O2 boosts bacterial survival and evolvability against oxidative stress. PMID:32163413
A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation. PMID:32160526
Rpn4 and proteasome-mediated yeast resistance to ethanol includes regulation of autophagy. PMID:32157425
Laser microdissection-based microproteomics of the hippocampus of a rat epilepsy model reveals regional differences in protein abundances. PMID:32157145
Mortalin (HSPA9) facilitates BRAF-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability. PMID:32156782
Post-Transcriptional Dysregulation of microRNA and Alternative Polyadenylation in Colorectal Cancer. PMID:32153636
Identification of Core Gene Expression Signature and Key Pathways in Colorectal Cancer. PMID:32153633
Synovial fibroblast-derived exosomal microRNA-106b suppresses chondrocyte proliferation and migration in rheumatoid arthritis via down-regulation of PDK4. PMID:32152704
Recurrence-Associated Multi-RNA Signature to Predict Disease-Free Survival for Ovarian Cancer Patients. PMID:32149080
Evidence for binary Smc complexes lacking kite subunits in archaea. PMID:32148848
Applications of Network Pharmacology in Traditional Chinese Medicine Research. PMID:32148533
Identification of hub genes and pathways in adrenocortical carcinoma by integrated bioinformatic analysis. PMID:32147961
Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration. PMID:32142407
The Prognostic Significance of Metabolic Syndrome and a Related Six-lncRNA Signature in Esophageal Squamous Cell Carcinoma. PMID:32133283
Preferential gene retention increases the robustness of cold regulation in Brassicaceae and other plants after polyploidization. PMID:32133148
The iTRAQ-based chloroplast proteomic analysis of Triticum aestivum L. leaves subjected to drought stress and 5-aminolevulinic acid alleviation reveals several proteins involved in the protection of photosynthesis. PMID:32131734
Development and validation of hub genes for lymph node metastasis in patients with prostate cancer. PMID:32130760
Automated sample preparation with SP3 for low-input clinical proteomics. PMID:32129943
Supervised learning is an accurate method for network-based gene classification. PMID:32129827
Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions. PMID:32128395
Identification of rare variants in novel candidate genes in pulmonary atresia patients by next generation sequencing. PMID:32128068
Weighted gene co-expression network analysis identified MYL9 and CNN1 are associated with recurrence in colorectal cancer. PMID:32127961
An Integrated Analysis of mRNA and lncRNA Expression Profiles Indicates Their Potential Contribution to Brown Fat Dysfunction With Aging. PMID:32127793
The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts. PMID:32123204
Stem Cell-Derived Endothelial Cell Model that Responds to Tobacco Smoke Like Primary Endothelial Cells. PMID:32119531
Identification of 67 Pleiotropic Genes Associated With Seven Autoimmune/Autoinflammatory Diseases Using Multivariate Statistical Analysis. PMID:32117227
Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea. PMID:32116546
The proppin Bcas3 and its interactor KinkyA localize to the early phagophore and regulate autophagy. PMID:32116088
Identification of significant gene biomarkers of low back pain caused by changes in the osmotic pressure of nucleus pulposus cells. PMID:32111963
The Drosophila RNA Helicase Belle (DDX3) Non-Autonomously Suppresses Germline Tumorigenesis Via Regulation of a Specific mRNA Set. PMID:32111103
Network Properties of Cancer Prognostic Gene Signatures in the Human Protein Interactome. PMID:32111006
Co-expression network analysis reveals the pivotal role of mitochondrial dysfunction and interferon signature in juvenile dermatomyositis. PMID:32110496
Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit. PMID:32109376
Integrative module analysis of HCC gene expression landscapes. PMID:32104233
Investigation of secondary metabolism in the industrial butanol hyper-producer Clostridium saccharoperbutylacetonicum N1-4. PMID:32103460
Predicted Drosophila Interactome Resource and web tool for functional interpretation of differentially expressed genes. PMID:32103267
Amhr2-Cre-Mediated Global Tspo Knockout. PMID:32099945
Identification of molecular markers associated with the progression and prognosis of endometrial cancer: a bioinformatic study. PMID:32099532
Identification of Candidate Genes and Therapeutic Agents for Light Chain Amyloidosis Based on Bioinformatics Approach. PMID:32099441
Snail synchronizes endocycling in a TOR-dependent manner to coordinate entry and escape from endoreplication pausing during the Drosophila critical weight checkpoint. PMID:32097403
Reverse vaccinology approach for the identification and characterization of outer membrane proteins of Shigella flexneri as potential cellular- and antibody-dependent vaccine candidates. PMID:32095437
Comparative modeling and mutual docking of structurally uncharacterized heat shock protein 70 and heat shock factor-1 proteins in water buffalo. PMID:32095057
Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP. PMID:32094787
An endophyte from salt-adapted Pokkali rice confers salt-tolerance to a salt-sensitive rice variety and targets a unique pattern of genes in its new host. PMID:32094443
Transcriptional insights into the CD8+ T cell response in mono-HIV and HCV infection. PMID:32093694
Quantitative proteomics analysis reveals important roles of N-glycosylation on ER quality control system for development and pathogenesis in Magnaporthe oryzae. PMID:32092131
Identification of Key Candidate Genes and Pathways of Candida albicans-Infected Human Umbilical Vein Endothelial Cells and Drug Screening. PMID:32089575
Immune correlates of postexposure vaccine protection against Marburg virus. PMID:32080323
Brain Cytoplasmic RNAs in Neurons: From Biosynthesis to Function. PMID:32079202
Global identification and analysis revealed differentially expressed lncRNAs associated with meiosis and low fertility in autotetraploid rice. PMID:32075588
Cuminal Inhibits Trichothecium roseum Growth by Triggering Cell Starvation: Transcriptome and Proteome Analysis. PMID:32075192
Changes in the proteome of sea urchin Paracentrotus lividus coelomocytes in response to LPS injection into the body cavity. PMID:32074628
Lumenal calcification and microvasculopathy in fetuin-A-deficient mice lead to multiple organ morbidity. PMID:32074120
Proteomic analysis of the antimicrobial effects of sublethal concentrations of thymol on Salmonella enterica serovar Typhimurium. PMID:32072194
A census of pathway maps in cancer systems biology. PMID:32066900
Characterisation of evolutionarily conserved key players affecting eukaryotic flagellar motility and fertility using a moss model. PMID:32064607
Enhancing reproducibility of gene expression analysis with known protein functional relationships: The concept of well-associated protein. PMID:32058996
Identification of Hub Genes and Pathways in Gastric Adenocarcinoma Based on Bioinformatics Analysis. PMID:32058995
Functional heterogeneity of lymphocytic patterns in primary melanoma dissected through single-cell multiplexing. PMID:32057296
Exploration of databases and methods supporting drug repurposing: a comprehensive survey. PMID:32055842
Protein Expression Profile in Rat Silicosis Model Reveals Upregulation of PTPN2 and Its Inhibitory Effect on Epithelial-Mesenchymal Transition by Dephosphorylation of STAT3. PMID:32054021
Axon microdissection and transcriptome profiling reveals the in vivo RNA content of fully differentiated myelinated motor axons. PMID:32051223
Identification of Urinary Biomarkers for Exercise-Induced Immunosuppression by iTRAQ Proteomics. PMID:32047808
DTranNER: biomedical named entity recognition with deep learning-based label-label transition model. PMID:32046638
A Network-Based Bioinformatics Approach to Identify Molecular Biomarkers for Type 2 Diabetes that Are Linked to the Progression of Neurological Diseases. PMID:32041280
Classification of Trispanins: A Diverse Group of Proteins That Function in Membrane Synthesis and Transport Mechanisms. PMID:32039202
Screening the Cancer Genome Atlas Database for Genes of Prognostic Value in Acute Myeloid Leukemia. PMID:32039005
Extent and characteristics of immune infiltration in clear cell renal cell carcinoma and the prognostic value. PMID:32038957
TNFα-Signaling Modulates the Kinase Activity of Human Effector Treg and Regulates IL-17A Expression. PMID:32038615
Kinobead/LC-MS Phosphokinome Profiling Enables Rapid Analyses of Kinase-Dependent Cell Signaling Networks. PMID:32037842
Determining sequencing depth in a single-cell RNA-seq experiment. PMID:32034137
Gene Prioritization through Consensus Strategy, Enrichment Methodologies Analysis, and Networking for Osteosarcoma Pathogenesis. PMID:32033398
Dysregulated iron metabolism in C. elegans catp-6/ATP13A2 mutant impairs mitochondrial function. PMID:32032734
MicroRNA exporter HuR clears the internalized pathogens by promoting pro-inflammatory response in infected macrophages. PMID:32031337
Identification of key genes and pathways in calcific aortic valve disease by bioinformatics analysis. PMID:32030260
Schizotypy-Related Magnetization of Cortex in Healthy Adolescence Is Colocated With Expression of Schizophrenia-Related Genes. PMID:32029217
Screening of Prognostic Factors in Early-Onset Breast Cancer. PMID:32028860
Identifying the key genes and microRNAs in prostate cancer bone metastasis by bioinformatics analysis. PMID:32027093
Neurofibromatosis Type 1 Implicates Ras Pathways in the Genetic Architecture of Neurodevelopmental Disorders. PMID:32026187
Pathway and network analysis of more than 2500 whole cancer genomes. PMID:32024854
The cox-filter method identifies respective subtype-specific lncRNA prognostic signatures for two human cancers. PMID:32024523
Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome. PMID:32024067
Bioinformatics for Renal and Urinary Proteomics: Call for Aggrandization. PMID:32024005
Use of a Systematic Pharmacological Methodology to Explore the Mechanism of Shengmai Powder in Treating Diabetic Cardiomyopathy. PMID:32023237
Mechanism of tanshinones and phenolic acids from Danshen in the treatment of coronary heart disease based on co-expression network. PMID:32020855
Identification of cancer driver genes based on nucleotide context. PMID:32015527
Proteome Analyses Reveal Macrophomina phaseolina's Survival Tools When Challenged by Burkholderia contaminans NZ. PMID:32010805
Screening of potential biomarkers and their predictive value in early stage non-small cell lung cancer: a bioinformatics analysis. PMID:32010558
Si-Ni-San Prevents Reserpine-Induced Depression by Inhibiting Inflammation and Regulating CYP450 Enzymatic Activity. PMID:32009949
Aging Disrupts the Circadian Patterns of Protein Expression in the Murine Hippocampus. PMID:32009941
The RNA-dependent RNA polymerase of enterovirus A71 associates with ribosomal proteins and positively regulates protein translation. PMID:32009553
Human and mouse essentiality screens as a resource for disease gene discovery. PMID:32005800
Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection. PMID:32001678
Bioinformatics-based screening of key genes for transformation of liver cirrhosis to hepatocellular carcinoma. PMID:32000807
Triangular correlation (TrC) between cancer aggressiveness, cell uptake capability, and cell deformability. PMID:31998832
Bioinformatics-Based Discovery of CKLF-Like MARVEL Transmembrane Member 5 as a Novel Biomarker for Breast Cancer. PMID:31998718
PIM1, CYP1B1, and HSPA2 Targeted by Quercetin Play Important Roles in Osteoarthritis Treatment by Achyranthes bidentata. PMID:31998395
Integrated Bioinformatics Analysis for the Identification of Key Molecules and Pathways in the Hippocampus of Rats After Traumatic Brain Injury. PMID:31997105
Metabolic syndrome diminishes insulin-induced Akt activation and causes a redistribution of Akt-interacting proteins in cardiomyocytes. PMID:31995605
A New Weighted Imputed Neighborhood-Regularized Tri-Factorization One-Class Collaborative Filtering Algorithm: Application to Target Gene Prediction of Transcription Factors. PMID:31995498
Organ-level protein networks as a reference for the host effects of the microbiome. PMID:31992612
Deconstructing the genetic architecture of iron deficiency chlorosis in soybean using genome-wide approaches. PMID:31992198
Identify potential clinical significance of long noncoding RNA forkhead box P4 antisense RNA 1 in patients with early stage pancreatic ductal adenocarcinoma. PMID:31991068
Proteomic profiling of proteins in the dorsal horn of the spinal cord in dairy cows with chronic lameness. PMID:31990932
Estrogen/estrogen receptor promotes the proliferation of endometrial carcinoma cells by enhancing hMOF expression. PMID:31990345
ADAPT identifies an ESCRT complex composition that discriminates VCaP from LNCaP prostate cancer cell exosomes. PMID:31989173
Genetic architecture study of rheumatoid arthritis and juvenile idiopathic arthritis. PMID:31988799
Genetic interaction screen for severe neurodevelopmental disorders reveals a functional link between Ube3a and Mef2 in Drosophila melanogaster. PMID:31988313
Common and distinct features of potentially predictive biomarkers in small cell lung carcinoma and large cell neuroendocrine carcinoma of the lung by systematic and integrated analysis. PMID:31981472
Tissue-specific transcriptomic changes associated with AmBisome® treatment of BALB/c mice with experimental visceral leishmaniasis. PMID:31976381
A Multi-Omics Analysis of Bone Morphogenetic Protein 5 (BMP5) mRNA Expression and Clinical Prognostic Outcomes in Different Cancers Using Bioinformatics Approaches. PMID:31973134
Inguinal Ring RNA Sequencing Reveals Downregulation of Muscular Genes Related to Scrotal Hernia in Pigs. PMID:31973088
Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform. PMID:31971940
Combined proteomics/miRNomics of dendritic cell immunotherapy-treated glioblastoma patients as a screening for survival-associated factors. PMID:31969991
Investigation of the EIL/EIN3 Transcription Factor Gene Family Members and Their Expression Levels in the Early Stage of Cotton Fiber Development. PMID:31968683
A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV. PMID:31968263
Tissue-guided LASSO for prediction of clinical drug response using preclinical samples. PMID:31967990
Site-directed targeting of transcriptional activation-associated proteins to repressed chromatin restores CRISPR activity. PMID:31967103
Proteomics-Based Evidence for a Pro-Oncogenic Role of ESRP1 in Human Colorectal Cancer Cells. PMID:31963158
Incorporating biological structure into machine learning models in biomedicine. PMID:31962244
WormQTL2: an interactive platform for systems genetics in Caenorhabditis elegans. PMID:31960906
Transcriptomic profiles reveal differences between the right and left ventricle in normoxia and hypoxia. PMID:31960631
Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. PMID:31959160
Transcriptome signature of ventricular arrhythmia in dilated cardiomyopathy reveals increased fibrosis and activated TP53. PMID:31958463
Prefoldin subunits (PFDN1-6) serve as poor prognostic markers in gastric cancer. PMID:31957800
In silico unravelling pathogen-host signaling cross-talks via pathogen mimicry and human protein-protein interaction networks. PMID:31956393
Exchange protein directly activated by cAMP (Epac) 1 plays an essential role in stress-induced exercise capacity by regulating PGC-1α and fatty acid metabolism in skeletal muscle. PMID:31955265
Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111. PMID:31952352
Comparative proteomic analysis of different stages of breast cancer tissues using ultra high performance liquid chromatography tandem mass spectrometer. PMID:31945087
Phosphatase POPX2 interferes with cell cycle by interacting with Chk1. PMID:31944151
Combining Bioinformatics and Experiments to Identify and Verify Key Genes with Prognostic Values in Endometrial Carcinoma. PMID:31942195
A Comprehensive Transcriptome-Wide Identification and Screening of WRKY Gene Family Engaged in Abiotic Stress in Glycyrrhiza glabra. PMID:31941983
Transcriptome meta-analysis reveals differences of immune profile between eutopic endometrium from stage I-II and III-IV endometriosis independently of hormonal milieu. PMID:31941945
De novo variants in exomes of congenital heart disease patients identify risk genes and pathways. PMID:31941532
Genome-wide DNA methylation and transcriptome changes in Mycobacterium tuberculosis with rifampicin and isoniazid resistance. PMID:31938429
Bioinformatic analysis of differential expression and core GENEs in breast cancer. PMID:31938209
Identification of key genes involved in the pathogenesis of cutaneous melanoma using bioinformatics analysis. PMID:31937175
In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells. PMID:31936599
Uncovering the Pharmacological Mechanism of Stemazole in the Treatment of Neurodegenerative Diseases Based on a Network Pharmacology Approach. PMID:31936558
12-h clock regulation of genetic information flow by XBP1s. PMID:31935211
The clinicopathological significance of decreased miR-125b-5p in hepatocellular carcinoma: evidence based on RT-qPCR, microRNA-microarray, and microRNA-sequencing. PMID:31933718
The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. PMID:31932738
Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys cahirinus and Scarring Mus musculus. PMID:31932597
OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages. PMID:31931285
Genetic landscape of prognostic value in pancreatic ductal adenocarcinoma microenvironment. PMID:31930046
Study of the Gastrointestinal Heat Retention Syndrome in Children: From Diagnostic Model to Biological Basis. PMID:31929814
Identification of gene expression profiles and immune cell infiltration signatures between low and high tumor mutation burden groups in bladder cancer. PMID:31929742
Glutathione peroxidase-1 regulates adhesion and metastasis of triple-negative breast cancer cells via FAK signaling. PMID:31926619
Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression. PMID:31926610
Transcriptome analysis defines myocardium gene signatures in children with ToF and ASD and reveals disease-specific molecular reprogramming in response to surgery with cardiopulmonary bypass. PMID:31924244
Integrated analysis of a ceRNA network reveals potential prognostic lncRNAs in gastric cancer. PMID:31923354
PLAG1 silencing promotes cell chemosensitivity in ovarian cancer via the IGF2 signaling pathway. PMID:31922228
Integrative Bioinformatics Approaches to Map Potential Novel Genes and Pathways Involved in Ovarian Cancer. PMID:31921802
ITGB5 Plays a Key Role in Escherichia coli F4ac-Induced Diarrhea in Piglets. PMID:31921118
Temporal Changes of Spinal Transcriptomic Profiles in Mice With Spinal Nerve Ligation. PMID:31920516
LncRNA XIST serves as a ceRNA to regulate the expression of ASF1A, BRWD1M, and PFKFB2 in kidney transplant acute kidney injury via sponging hsa-miR-212-3p and hsa-miR-122-5p. PMID:31914881
Histamine-mediated autocrine signaling in mesenteric perilymphatic mast cells. PMID:31913658
Efficacy of FGFR Inhibitors and Combination Therapies for Acquired Resistance in FGFR2-Fusion Cholangiocarcinoma. PMID:31911531
Human Plasma Protein Corona of Aβ Amyloid and Its Impact on Islet Amyloid Polypeptide Cross-Seeding. PMID:31909987
Differential Expression in Testis and Liver Transcriptomes from Four Species of Peromyscus (Rodentia: Cricetidae). PMID:31909812
Proteomic Analyses Reveal New Insights on the Antimicrobial Mechanisms of Chitosan Biopolymers and Their Nanosized Particles against Escherichia coli. PMID:31905672
Comprehensive genomic analysis of the DUF4228 gene family in land plants and expression profiling of ATDUF4228 under abiotic stresses. PMID:31900112
The pathogen Moniliophthora perniciosa promotes differential proteomic modulation of cacao genotypes with contrasting resistance to witches´ broom disease. PMID:31898482
POLR1B is upregulated and promotes cell proliferation in non-small cell lung cancer. PMID:31897183
Expression and function of long non-coding RNA LINC01420 in thyroid cancer. PMID:31897152
HSPA1A, HSPA1L and TRAP1 heat shock genes may be associated with prognosis in ovarian epithelial cancer. PMID:31897148
Identification of key genes involved in the development and progression of early-onset colorectal cancer by co-expression network analysis. PMID:31897128
Cathepsin L interacts with CDK2-AP1 as a potential predictor of prognosis in patients with breast cancer. PMID:31897127
Identification of altered biological processes in heterogeneous RNA-sequencing data by discretization of expression profiles. PMID:31889184
Proximal femoral head transcriptome reveals novel candidate genes related to epiphysiolysis in broiler chickens. PMID:31888477
Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue transcriptomic approach. PMID:31888468
Genomic insights on heterogeneous resistance to vancomycin and teicoplanin in Methicillin-resistant Staphylococcus aureus: A first report from South India. PMID:31887179
Deciphering Immune-Associated Genes to Predict Survival in Clear Cell Renal Cell Cancer. PMID:31886185
Identification of Key Genes and Prognostic Value Analysis in Hepatocellular Carcinoma by Integrated Bioinformatics Analysis. PMID:31886163
Identification and Verification of the Main Differentially Expressed Proteins in Gastric Cancer via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry. PMID:31886120
Unique molecular signature in mucolipidosis type IV microglia. PMID:31883529
ShinyGO: a graphical gene-set enrichment tool for animals and plants. PMID:31882993
Venn-diaNet : venn diagram based network propagation analysis framework for comparing multiple biological experiments. PMID:31881980
Analysis of gene expression profiles and protein-protein interaction networks in multiple tissues of systemic sclerosis. PMID:31881890
Genetic dissection of canine hip dysplasia phenotypes and osteoarthritis reveals three novel loci. PMID:31881848
Investigating host-bacterial interactions among enteric pathogens. PMID:31881845
Comparative Proteomic Analysis Reveals the Regulatory Effects of H2S on Salt Tolerance of Mangrove Plant Kandelia obovata. PMID:31878013
Gene Expression Meta-Analysis Reveals Concordance in Gene Activation, Pathway, and Cell-Type Enrichment in Dermatomyositis Target Tissues. PMID:31872188
The Impact of Stroma Admixture on Molecular Subtypes and Prognostic Gene Signatures in Serous Ovarian Cancer. PMID:31871106
Whole genome bisulfite sequencing of human spermatozoa reveals differentially methylated patterns from type 2 diabetic patients. PMID:31869513
Transcriptomic signature of gut microbiome-contacting cells in colon of spontaneously hypertensive rats. PMID:31869283
Association between ALS and retroviruses: evidence from bioinformatics analysis. PMID:31861978
Benchmarking network algorithms for contextualizing genes of interest. PMID:31860671
Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver. PMID:31857389
Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13. PMID:31856834
Integrate multi-omics data with biological interaction networks using Multi-view Factorization AutoEncoder (MAE). PMID:31856727
Identification of prognostic genes in adrenocortical carcinoma microenvironment based on bioinformatic methods. PMID:31856409
Prolonged fasting followed by refeeding modifies proteome profile and parvalbumin expression in the fast-twitch muscle of pacu (Piaractus mesopotamicus). PMID:31856193
Regulation of color transition in purple tea (Camellia sinensis). PMID:31853722
Low-Dose Aspirin Treatment Attenuates Male Rat Salt-Sensitive Hypertension via Platelet Cyclooxygenase 1 and Complement Cascade Pathway. PMID:31852420
Transcriptome Analysis Identifies Immune Markers Related to Visceral Leishmaniasis Establishment in the Experimental Model of BALB/c Mice. PMID:31849951
Development and validation of a nomogram with an autophagy-related gene signature for predicting survival in patients with glioblastoma. PMID:31844032
Quantitative proteomic characterization of human sperm cryopreservation: using data-independent acquisition mass spectrometry. PMID:31842847
A systematic analysis of immune genes and overall survival in cancer patients. PMID:31842801
Mice lacking uterine enhancer of zeste homolog 2 have transcriptomic changes associated with uterine epithelial proliferation. PMID:31841397
Temporal VEGFA responsive genes in HUVECs: Gene signatures and potential ligands/receptors fine-tuning angiogenesis. PMID:31840205
Induction of PrMADS10 on the lower side of bent pine tree stems: potential role in modifying plant cell wall properties and wood anatomy. PMID:31831838
Handling Noise in Protein Interaction Networks. PMID:31828144
Finnish Parkinson's disease study integrating protein-protein interaction network data with exome sequencing analysis. PMID:31827228
A comprehensive in silico analysis, distribution and frequency of human Nkx2-5 mutations; A critical gene in congenital heart disease. PMID:31824610
Long Noncoding RNA LINC00265 Targets EGFR and Promotes Deterioration of Colorectal Cancer: A Comprehensive Study Based on Data Mining and in vitro Validation. PMID:31824175
Network Pharmacology of Yougui Pill Combined with Buzhong Yiqi Decoction for the Treatment of Sexual Dysfunction. PMID:31814838
Comprehensive analysis of vitreous chemokines involved in ischemic retinal vein occlusion. PMID:31814701
NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk. PMID:31811028
Bioinformatics Analysis of Expression and Alterations of BARD1 in Breast Cancer. PMID:31808361
Identification of key candidate genes and pathways in endometrial cancer: Evidence from bioinformatics analysis. PMID:31807178
Molecular response of Deinococcus radiodurans to simulated microgravity explored by proteometabolomic approach. PMID:31804539
Exploring the Pharmacological Mechanism of Quercetin-Resveratrol Combination for Polycystic Ovary Syndrome: A Systematic Pharmacological Strategy-Based Research. PMID:31804513
DYRK1A Overexpression Alters Cognition and Neural-Related Proteomic Pathways in the Hippocampus That Are Rescued by Green Tea Extract and/or Environmental Enrichment. PMID:31803016
TIMP1 Is A Potential Key Gene Associated With The Pathogenesis And Prognosis Of Ulcerative Colitis-Associated Colorectal Cancer. PMID:31802901
DeepMiR2GO: Inferring Functions of Human MicroRNAs Using a Deep Multi-Label Classification Model. PMID:31801264
Analysis of miRNA expression profiles in the liver of Clock Δ19 mutant mice. PMID:31799078
Multi-dimensional computational pipeline for large-scale deep screening of compound effect assessment: an in silico case study on ageing-related compounds. PMID:31798962
Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss. PMID:31798899
A novel circRNA-miRNA-mRNA network identifies circ-YOD1 as a biomarker for coronary artery disease. PMID:31797949
PGxMine: Text mining for curation of PharmGKB. PMID:31797632
A Literature-Based Knowledge Graph Embedding Method for Identifying Drug Repurposing Opportunities in Rare Diseases. PMID:31797619
Graph-based information diffusion method for prioritizing functionally related genes in protein-protein interaction networks. PMID:31797617
Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis. PMID:31791268
Bioinformatic analysis identifies potentially key differentially expressed genes in oncogenesis and progression of clear cell renal cell carcinoma. PMID:31788359
Bioinformatics analysis of Ewing's sarcoma: Seeking key candidate genes and pathways. PMID:31788075
The core genes involved in the promotion of depression in patients with ovarian cancer. PMID:31788074
Exon-Mediated Activation of Transcription Starts. PMID:31787377
Analysis of key genes and their functions in placental tissue of patients with gestational diabetes mellitus. PMID:31783860
A history of opioid exposure in females increases the risk of metabolic disorders in their future male offspring. PMID:31782234
Cytokine signatures associate with disease severity in children with Mycoplasma pneumoniae pneumonia. PMID:31780733
Carprofen-induced depletion of proton motive force reverses TetK-mediated doxycycline resistance in methicillin-resistant Staphylococcus pseudintermedius. PMID:31780689
The State-of-the Art of Environmental Toxicogenomics: Challenges and Perspectives of "Omics" Approaches Directed to Toxicant Mixtures. PMID:31779274
Network Modeling Approaches and Applications to Unravelling Non-Alcoholic Fatty Liver Disease. PMID:31771247
Screening and identification of key biomarkers in nasopharyngeal carcinoma: Evidence from bioinformatic analysis. PMID:31770211
JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. PMID:31767855
MicroRNA-101 Protects Against Cardiac Remodeling Following Myocardial Infarction via Downregulation of Runt-Related Transcription Factor 1. PMID:31766975
MicroRNA expression signatures of atrial fibrillation: The critical systematic review and bioinformatics analysis. PMID:31766887
Phylostratigraphic Analysis Shows the Earliest Origination of the Abiotic Stress Associated Genes in A. thaliana. PMID:31766757
Unraveling the Adipose Tissue Proteome of Transition Cows through Severe Negative Energy Balance. PMID:31766506
Identification of the potential biomarkers in patients with glioma: a weighted gene co-expression network analysis. PMID:31761927
Repurposing Drugs by In Silico Methods to Target BCR Kinase Domain in Chronic Myeloid Leukemia. PMID:31759365
Identification of actin network proteins, talin-1 and filamin-A, in circulating extracellular vesicles as blood biomarkers for human myalgic encephalomyelitis/chronic fatigue syndrome. PMID:31759091
Ontology-based prediction of cancer driver genes. PMID:31757986
A Non-amyloid Prion Particle that Activates a Heritable Gene Expression Program. PMID:31757755
Monocytes affect bone mineral density in pre- and postmenopausal women through ribonucleoprotein complex biogenesis by integrative bioinformatics analysis. PMID:31754224
Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI. PMID:31754094
Identifying gene function and module connections by the integration of multispecies expression compendia. PMID:31754022
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens. PMID:31744546
Discovery of disease- and drug-specific pathways through community structures of a literature network. PMID:31738408
Is MYND Domain-Mediated Assembly of SMYD3 Complexes Involved in Calcium Dependent Signaling? PMID:31737645
Systematic analysis identifies three-lncRNA signature as a potentially prognostic biomarker for lung squamous cell carcinoma using bioinformatics strategy. PMID:31737498
Protein Interactions Network of Hepatitis E Virus RNA and Polymerase With Host Proteins. PMID:31736926
Multiple interaction nodes define the postreplication repair response to UV-induced DNA damage that is defective in melanomas and correlated with UV signature mutation load. PMID:31733171
Reanalysis of Lactobacillus paracasei Lbs2 Strain and Large-Scale Comparative Genomics Places Many Strains into Their Correct Taxonomic Position. PMID:31731444
Identification of key biomarkers associated with development and prognosis in patients with ovarian carcinoma: evidence from bioinformatic analysis. PMID:31729978
Deciphering signalling network in broad spectrum Near Isogenic Lines of rice resistant to Magnaporthe oryzae. PMID:31729398
Transcriptome analysis of miRNA and mRNA in the livers of pigs with highly diverged backfat thickness. PMID:31727987
Proteomics Recapitulates Ovarian Proteins Relevant to Puberty and Fertility in Brahman Heifers (Bos indicus L.). PMID:31726744
Homology modeling and molecular dynamics dimulation study of β carbonic anhydrase of Ascaris lumbricoides. PMID:31719767
KRAS regulation by small non-coding RNAs and SNARE proteins. PMID:31712554
Identification of Potential Biomarkers in Association With Progression and Prognosis in Epithelial Ovarian Cancer by Integrated Bioinformatics Analysis. PMID:31708970
Effects of Simulated Space Radiations on the Tomato Root Proteome. PMID:31708949
Copy number variation is highly correlated with differential gene expression: a pan-cancer study. PMID:31706287
Significant random signatures reveals new biomarker for breast cancer. PMID:31703592
Mitochondrial dysfunction in rheumatoid arthritis: A comprehensive analysis by integrating gene expression, protein-protein interactions and gene ontology data. PMID:31703070
Causal Inference Engine: a platform for directional gene set enrichment analysis and inference of active transcriptional regulators. PMID:31701125
Identification of key candidate genes and molecular pathways in white fat browning: an anti-obesity drug discovery based on computational biology. PMID:31699147
LGR5 and Downstream Intracellular Signaling Proteins Play Critical Roles in the Cell Proliferation of Neuroblastoma, Meningioma and Pituitary Adenoma. PMID:31698554
Weighted gene co-expression network analysis reveals specific modules and hub genes related to neuropathic pain in dorsal root ganglions. PMID:31696225
Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide. PMID:31695851
Gene- and Disease-Based Expansion of the Knowledge on Inborn Errors of Immunity. PMID:31695696
TCDD-Inducible Poly-ADP-Ribose Polymerase (TIPARP), A Novel Therapeutic Target Of Breast Cancer. PMID:31695491
Co-regulation map of the human proteome enables identification of protein functions. PMID:31690884
Digital Immune Gene Expression Profiling Discriminates Allergic Rhinitis Responders from Non-Responders to Probiotic Supplementation. PMID:31690037
Differential gene expression identifies KRT7 and MUC1 as potential metastasis-specific targets in sarcoma. PMID:31686913
Dietary L-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut. PMID:31686025
Network-based Biased Tree Ensembles (NetBiTE) for Drug Sensitivity Prediction and Drug Sensitivity Biomarker Identification in Cancer. PMID:31685861
The NGFR100W Mutation Specifically Impairs Nociception without Affecting Cognitive Performance in a Mouse Model of Hereditary Sensory and Autonomic Neuropathy Type V. PMID:31685654
'One DB to rule them all'-the RING: a Regulatory INteraction Graph combining TFs, genes/proteins, SNPs, diseases and drugs. PMID:31682269
PRODIGY: personalized prioritization of driver genes. PMID:31681944
Novel Biomarkers Associated With Progression and Prognosis of Bladder Cancer Identified by Co-expression Analysis. PMID:31681575
Integrated Network Analysis Reveals FOXM1 and MYBL2 as Key Regulators of Cell Proliferation in Non-small Cell Lung Cancer. PMID:31681566
Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities. PMID:31676584
Analysis of Arabidopsis thaliana Redox Gene Network Indicates Evolutionary Expansion of Class III Peroxidase in Plants. PMID:31673065
Identifying hub genes of clear cell renal cell carcinoma associated with the proportion of regulatory T cells by weighted gene co-expression network analysis. PMID:31672930
Benchmarking two Saccharomyces cerevisiae laboratory strains for growth and transcriptional response to methanol. PMID:31667368
Reverse diauxie phenotype in Pseudomonas aeruginosa biofilm revealed by exometabolomics and label-free proteomics. PMID:31666981
Systematic Pharmacological Methodology to Explore the Pharmacological Mechanism of Siwu Decoction for Osteoporosis. PMID:31666500
Molecular Diversification of the Seminal Fluid Proteome in a Recently Diverged Passerine Species Pair. PMID:31665510
Set cover-based methods for motif selection. PMID:31665223
Identifying novel biomarkers of the pediatric influenza infection by weighted co-expression network analysis. PMID:31665046
Transcriptome analysis of dog oral melanoma and its oncogenic analogy with human melanoma. PMID:31661138
RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung adenocarcinoma. PMID:31661124
Dynamic transcriptome sequencing and analysis during early development in the bighead carp (Hypophthalmichthys nobilis). PMID:31660854
FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer. PMID:31660083
Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells. PMID:31659149
Proteomic Analysis of Primary Colon Cancer and Synchronous Solitary Liver Metastasis. PMID:31659112
Prediction of off-target specificity and cell-specific fitness of CRISPR-Cas System using attention boosted deep learning and network-based gene feature. PMID:31658261
Brain Region-Specific nAChR and Associated Protein Abundance Alterations Following Chronic Nicotine and/or Menthol Exposure. PMID:31657575
Generation of semi-dwarf rice (Oryza sativa L.) lines by CRISPR/Cas9-directed mutagenesis of OsGA20ox2 and proteomic analysis of unveiled changes caused by mutations. PMID:31656725
Increased expression of TET3 predicts unfavorable prognosis in patients with ovarian cancer-a bioinformatics integrative analysis. PMID:31656201
The sensor kinase MtrB of Mycobacterium tuberculosis regulates hypoxic survival and establishment of infection. PMID:31653701
Suppression of the Peripheral Immune System Limits the Central Immune Response Following Cuprizone-Feeding: Relevance to Modelling Multiple Sclerosis. PMID:31653054
A Method for the Structure-Based, Genome-Wide Analysis of Bacterial Intergenic Sequences Identifies Shared Compositional and Functional Features. PMID:31652625
Hypergraph-based connectivity measures for signaling pathway topologies. PMID:31652258
ACAT1 and Metabolism-Related Pathways Are Essential for the Progression of Clear Cell Renal Cell Carcinoma (ccRCC), as Determined by Co-expression Network Analysis. PMID:31649873
Potential molecular mechanism of ACE gene at different time points in STEMI patients based on genome-wide microarray dataset. PMID:31647035
Trichostatin A, a Histone Deacetylase Inhibitor, Alleviates Eosinophilic Meningitis Induced by Angiostrongylus cantonensis Infection in Mice. PMID:31636619
Genetic architecture of subcortical brain structures in 38,851 individuals. PMID:31636452
Identification of biomarker microRNA-mRNA regulatory pairs for predicting the docetaxel resistance in prostate cancer. PMID:31632491
Enzymatic Digestion of Hyaluronan-Based Brain Extracellular Matrix in vivo Can Induce Seizures in Neonatal Mice. PMID:31632233
SILAC-based quantitative proteomics using mass spectrometry quantifies endoplasmic reticulum stress in whole HeLa cells. PMID:31628211
Exploring the Molecular Crosstalk between Pancreatic Bud and Mesenchyme in Embryogenesis: Novel Signals Involved. PMID:31623299
Bioinformatics Analysis Identifies MicroRNAs and Target Genes Associated with Prognosis in Patients with Melanoma. PMID:31621692
Interactome of the Autoimmune Risk Protein ANKRD55. PMID:31620119
PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages. PMID:31619507
Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome. PMID:31616248
Pharmacogenomics, biomarker network, and allele frequencies in colorectal cancer. PMID:31616044
Neglog: Homology-Based Negative Data Sampling Method for Genome-Scale Reconstruction of Human Protein-Protein Interaction Networks. PMID:31614890
Identification of a Nine-Gene Signature and Establishment of a Prognostic Nomogram Predicting Overall Survival of Pancreatic Cancer. PMID:31612115
Screening and identification of key biomarkers in lung squamous cell carcinoma by bioinformatics analysis. PMID:31612029
Evaluation of the target genes of arsenic trioxide in pancreatic cancer by bioinformatics analysis. PMID:31612027
Screening and identification of key biomarkers in adrenocortical carcinoma based on bioinformatics analysis. PMID:31611976
Screening and authentication of molecular markers in malignant glioblastoma based on gene expression profiles. PMID:31611967
AKR1C1-3, notably AKR1C3, are distinct biomarkers for liver cancer diagnosis and prognosis: Database mining in malignancies. PMID:31611960
Identification of key biomarkers and potential molecular mechanisms in lung cancer by bioinformatics analysis. PMID:31611952
Tensor Decomposition-Based Unsupervised Feature Extraction Applied to Single-Cell Gene Expression Analysis. PMID:31608111
Quantitative Proteomics Reveals a Role for SERINE/ARGININE-Rich 45 in Regulating RNA Metabolism and Modulating Transcriptional Suppression via the ASAP Complex in Arabidopsis thaliana. PMID:31608083
The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway. PMID:31604991
Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis. PMID:31604843
Smoking alters the evolutionary trajectory of non-small cell lung cancer. PMID:31602204
MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2. PMID:31601272
EuRBPDB: a comprehensive resource for annotation, functional and oncological investigation of eukaryotic RNA binding proteins (RBPs). PMID:31598693
Tandem mass tag-based quantitative proteomic analysis of lycorine treatment in highly pathogenic avian influenza H5N1 virus infection. PMID:31592345
Loss of CYLD accelerates melanoma development and progression in the Tg(Grm1) melanoma mouse model. PMID:31591386
Graph embedding on biomedical networks: methods, applications and evaluations. PMID:31584634
Blinded Testing of Function Annotation for uPE1 Proteins by I-TASSER/COFACTOR Pipeline Using the 2018-2019 Additions to neXtProt and the CAFA3 Challenge. PMID:31581775
Using text-mined trait data to test for cooperate-and-radiate co-evolution between ants and plants. PMID:31581264
Transcriptome analysis of Xanthomonas oryzae pv. oryzicola exposed to H2O2 reveals horizontal gene transfer contributes to its oxidative stress response. PMID:31581193
Identification of key pathways and genes in colorectal cancer to predict the prognosis based on mRNA interaction network. PMID:31579079
Deep sequencing analysis to identify novel and rare variants in pain-related genes in patients with acute postoperative pain and high morphine use. PMID:31571979
MicroRNA-424 regulates cisplatin resistance of gastric cancer by targeting SMURF1 based on GEO database and primary validation in human gastric cancer tissues. PMID:31571913
Micro RNA Transcriptome Profile in Canine Oral Melanoma. PMID:31569419
Identification of gene and microRNA changes in response to smoking in human airway epithelium by bioinformatics analyses. PMID:31568004
Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells. PMID:31562326
Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration. PMID:31560769
Decreased expression of microRNAs targeting type-2 diabetes susceptibility genes in peripheral blood of patients and predisposed individuals. PMID:31559537
Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer. PMID:31558802
NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis. PMID:31558756
Elevated hsa-miR-590-3p expression down-regulates HMGB2 expression and contributes to the severity of IgA nephropathy. PMID:31557418
Identification of key genes and microRNAs involved in kidney Wilms tumor by integrated bioinformatics analysis. PMID:31555364
Network-based method for drug target discovery at the isoform level. PMID:31554914
The EFI Web Resource for Genomic Enzymology Tools: Leveraging Protein, Genome, and Metagenome Databases to Discover Novel Enzymes and Metabolic Pathways. PMID:31553576
Nipah Virus-Like Particle Egress Is Modulated by Cytoskeletal and Vesicular Trafficking Pathways: a Validated Particle Proteomics Analysis. PMID:31551400
Drug repurposing for breast cancer therapy: Old weapon for new battle. PMID:31550502
SoyCSN: Soybean context-specific network analysis and prediction based on tissue-specific transcriptome data. PMID:31549018
Synergistic effects of common schizophrenia risk variants. PMID:31548722
Plasma Protein Comparison between Dairy Cows with Inactive Ovaries and Estrus. PMID:31548586
Genome-wide RNAi screen in Drosophila reveals Enok as a novel trithorax group regulator. PMID:31547845
Transcriptomic Signatures of Experimental Alkaloid Consumption in a Poison Frog. PMID:31546679
Identification and evolutionary characterization of salt-responsive transcription factors in the succulent halophyte Suaeda fruticosa. PMID:31545841
Microarray‑based analysis of COL11A1 and TWIST1 as important differentially‑expressed pathogenic genes between left and right‑sided colon cancer. PMID:31545476
The four‑microRNA signature identified by bioinformatics analysis predicts the prognosis of nasopharyngeal carcinoma patients. PMID:31545473
Exploring the active mechanism of berberine against HCC by systematic pharmacology and experimental validation. PMID:31545468
Transcriptomic analysis and identification of prognostic biomarkers in cholangiocarcinoma. PMID:31545466
miR‑126a‑5p‑Dbp and miR‑31a‑Crot/Mrpl4 interaction pairs crucial for the development of hypertension and stroke. PMID:31545431
Refinements of LC-MS/MS Spectral Counting Statistics Improve Quantification of Low Abundance Proteins. PMID:31541118
The Anti-Apoptotic Effect of ASC-Exosomes in an In Vitro ALS Model and Their Proteomic Analysis. PMID:31540100
Genome-wide identification and expression profile analysis of nuclear factor Y family genes in Sorghum bicolor L. (Moench). PMID:31536532
Crucial lncRNAs associated with adipocyte differentiation from human adipose-derived stem cells based on co-expression and ceRNA network analyses. PMID:31534842
Noninvasive application of mesenchymal stem cell spheres derived from hESC accelerates wound healing in a CXCL12-CXCR4 axis-dependent manner. PMID:31534540
Noninvasive Identification of Immune-Related Biomarkers in Hepatocellular Carcinoma. PMID:31531018
ApicoTFdb: the comprehensive web repository of apicomplexan transcription factors and transcription-associated co-factors. PMID:31529106
Identification of proteins and miRNAs that specifically bind an mRNA in vivo. PMID:31527589
Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: a transcriptome analysis. PMID:31523389
Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation. PMID:31521603
Comparative study of excretory-secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata. PMID:31521183
Genetic Basis of Obesity and Type 2 Diabetes in Africans: Impact on Precision Medicine. PMID:31520154
Identification of differentially expressed genes between primary lung cancer and lymph node metastasis via bioinformatic analysis. PMID:31516588
Bioinformatics analysis identifies hub genes and pathways in nasopharyngeal carcinoma. PMID:31516577
Effect of hyperoside on cervical cancer cells and transcriptome analysis of differentially expressed genes. PMID:31516392
SPTAN1 variants as a potential cause for autosomal recessive hereditary spastic paraplegia. PMID:31515523
Lipocalin-2 (Lcn-2) Attenuates Polymicrobial Sepsis with LPS Preconditioning (LPS Tolerance) in FcGRIIb Deficient Lupus Mice. PMID:31514375
PFN1 and integrin-β1/mTOR axis involvement in cornea differentiation of fibroblast limbal stem cells. PMID:31513338
Functional expression and impact of testis-specific gene antigen 10 in breast cancer: a combined in vitro and in silico analysis. PMID:31508330
MEK1/2 Inhibitors Unlock the Constrained Interferon Response in Macrophages Through IRF1 Signaling. PMID:31507609
Exosomal miR-1246 in serum as a potential biomarker for early diagnosis of gastric cancer. PMID:31506750
Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study. PMID:31506343
Possible Molecular Mechanisms for the Roles of MicroRNA-21 Played in Lung Cancer. PMID:31506038
New insights on human essential genes based on integrated analysis and the construction of the HEGIAP web-based platform. PMID:31504171
Gene Cascade Finder: A tool for identification of gene cascades and its application in Caenorhabditis elegans. PMID:31504044
Gestational Diabetes Mellitus Regulatory Network Identifies hsa-miR-145-5p and hsa-miR-875-5p as Potential Biomarkers. PMID:31497041
Profiling of remote skeletal muscle gene changes resulting from stimulation of atopic dermatitis disease in NC/Nga mouse model. PMID:31496874
Pseudomonas spp. are key players in agricultural biogas substrate degradation. PMID:31492882
Classification of early and late stage liver hepatocellular carcinoma patients from their genomics and epigenomics profiles. PMID:31490960
Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice. PMID:31489782
Transient receptor potential ankyrin1 channel is endogenously expressed in T cells and is involved in immune functions. PMID:31488616
Hypoxic exosomes facilitate angiogenesis and metastasis in esophageal squamous cell carcinoma through altering the phenotype and transcriptome of endothelial cells. PMID:31488217
TPM2 as a potential predictive biomarker for atherosclerosis. PMID:31487691
Signaling pathways and gene co-expression modules associated with cytoskeleton and axon morphology in breast cancer survivors with chronic paclitaxel-induced peripheral neuropathy. PMID:31486345
Comparative transcriptomic analysis reveals beneficial effect of dietary mulberry leaves on the muscle quality of finishing pigs. PMID:31486291
Identification of Potential Biomarkers and Survival Analysis for Head and Neck Squamous Cell Carcinoma Using Bioinformatics Strategy: A Study Based on TCGA and GEO Datasets. PMID:31485443
Label-Free Proteomics Revealed Oxidative Stress and Inflammation as Factors That Enhance Chemoresistance in Luminal Breast Cancer. PMID:31485295
Molecular modelling and docking of Mus musculus HMGB1 inflammatory protein with CGA. PMID:31485132
Copy number variants in lipid metabolism genes are associated with gallstones disease in men. PMID:31485028
The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation. PMID:31485003
Identification of Hub Genes and Key Pathways Associated With Bipolar Disorder Based on Weighted Gene Co-expression Network Analysis. PMID:31481902
The interaction of YBX1 with G3BP1 promotes renal cell carcinoma cell metastasis via YBX1/G3BP1-SPP1- NF-κB signaling axis. PMID:31481087
Benchmarking network propagation methods for disease gene identification. PMID:31479437
The molecular origin and taxonomy of mucinous ovarian carcinoma. PMID:31477716
Astrocytes are direct cellular targets of lithium treatment: novel roles for lysyl oxidase and peroxisome-proliferator activated receptor-γ as astroglial targets of lithium. PMID:31477687
Exploration of tissue-specific gene expression patterns underlying timing of breeding in contrasting temperature environments in a song bird. PMID:31477015
Assessment of network module identification across complex diseases. PMID:31471613
Discovery and Characterization of Native Deinococcus radiodurans Promoters for Tunable Gene Expression. PMID:31471304
Cyclin-CDK Complexes are Key Controllers of Capacitation-Dependent Actin Dynamics in Mammalian Spermatozoa. PMID:31470670
Identification of modules and functional analysis in CRC subtypes by integrated bioinformatics analysis. PMID:31469863
GRAM: A GeneRAlized Model to predict the molecular effect of a non-coding variant in a cell-type specific manner. PMID:31469829
Gene Expression Predicts Histological Severity and Reveals Distinct Molecular Profiles of Nonalcoholic Fatty Liver Disease. PMID:31467298
Quantifying Risk Pathway Crosstalk Mediated by miRNA to Screen Precision drugs for Breast Cancer Patients. PMID:31466383
Multiscale network analysis reveals molecular mechanisms and key regulators of the tumor microenvironment in gastric cancer. PMID:31463974
Measuring rank robustness in scored protein interaction networks. PMID:31462221
Genetic Signatures of Drug Response Variability in Drosophila melanogaster. PMID:31455722
Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes. PMID:31452935
Leucine rich repeat LGI family member 3: Integrative analyses reveal its prognostic association with non-small cell lung cancer. PMID:31452819
Screening and identification of potential target genes in head and neck cancer using bioinformatics analysis. PMID:31452775
Identification of key genes and pathways between type I and type II endometrial cancer using bioinformatics analysis. PMID:31452737
Identification of potential agents for thymoma by integrated analyses of differentially expressed tumour-associated genes and molecular docking experiments. PMID:31452699
Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment. A multidisciplinary investigation. PMID:31451429
Comprehensive analysis of the lysine acetylome in Aeromonas hydrophila reveals cross-talk between lysine acetylation and succinylation in LuxS. PMID:31448697
On the Role of Bioinformatics and Data Science in Industrial Microbiome Applications. PMID:31447883
Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain. PMID:31447098
A Plasmodium berghei putative serine-threonine kinase 2 (PBANKA_0311400) is required for late liver stage development and timely initiation of blood stage infection. PMID:31444161
ProtFus: A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins. PMID:31437145
Integrating multiomics longitudinal data to reconstruct networks underlying lung development. PMID:31432713
Clinical significance and prospective molecular mechanism of C‑C motif chemokine receptors in patients with early‑stage pancreatic ductal adenocarcinoma after pancreaticoduodenectomy. PMID:31432181
lncRNA/circRNA‑miRNA‑mRNA ceRNA network in lumbar intervertebral disc degeneration. PMID:31432173
MAP‑1B, PACS‑2 and AHCYL1 are regulated by miR‑34A/B/C and miR‑449 in neuroplasticity following traumatic spinal cord injury in rats: Preliminary explorative results from microarray data. PMID:31432119
Identification of Potential Crucial Genes and Key Pathways in Breast Cancer Using Bioinformatic Analysis. PMID:31428132
Differentially Expressed MiRNAs and tRNA Genes Affect Host Homeostasis During Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Infections in Young Pigs. PMID:31428130
iTRAQ-based quantitative analysis reveals proteomic changes in Chinese cabbage (Brassica rapa L.) in response to Plasmodiophora brassicae infection. PMID:31427711
Hepatitis C Virus Entry: Protein Interactions and Fusion Determinants Governing Productive Hepatocyte Invasion. PMID:31427285
Administration of a Postbiotic Causes Immunomodulatory Responses in Broiler Gut and Reduces Disease Pathogenesis Following Challenge. PMID:31426502
Analysis of transcription factor- and ncRNA-mediated potential pathogenic gene modules in Alzheimer's disease. PMID:31422384
TGF-β-induced transgelin promotes bladder cancer metastasis by regulating epithelial-mesenchymal transition and invadopodia formation. PMID:31420300
Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson's disease. PMID:31419995
Plasmodium helical interspersed subtelomeric family-an enigmatic piece of the Plasmodium biology puzzle. PMID:31418110
Retained Acetylated Histone Four in Bull Sperm Associated With Fertility. PMID:31417913
Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis. PMID:31417909
Gene expression profiling reveals candidate biomarkers and probable molecular mechanism in diabetic peripheral neuropathy. PMID:31413612
UNIPred-Web: a web tool for the integration and visualization of biomolecular networks for protein function prediction. PMID:31412768
The "other" 15-40%: The Role of Non-Collagenous Extracellular Matrix Proteins and Minor Collagens in Tendon. PMID:31410892
The prognostic value of LINC01296 in pan-cancers and the molecular regulatory mechanism in hepatocellular carcinoma: a comprehensive study based on data mining, bioinformatics, and in vitro validation. PMID:31410029
A network pharmacology-based study on the anti-hepatoma effect of Radix Salviae Miltiorrhizae. PMID:31406500
Secretome profiling of PC3/nKR cells, a novel highly migrating prostate cancer subline derived from PC3 cells. PMID:31404090
Identification of transcription factor binding sites on promoter of RNA dependent RNA polymerases (RDRs) and interacting partners of RDR proteins through in silico analysis. PMID:31402824
Blood transcriptomic biomarker as a surrogate of ischemic brain gene expression. PMID:31400065
Lamin A/C dysregulation contributes to cardiac pathology in a mouse model of severe spinal muscular atrophy. PMID:31397869
Proteomic analysis of Plasmodium falciparum response to isocryptolepine derivative. PMID:31393938
Identification of significant gene and pathways involved in HBV-related hepatocellular carcinoma by bioinformatics analysis. PMID:31392101
SPOP regulates the DNA damage response and lung adenocarcinoma cell response to radiation. PMID:31392082
Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome. PMID:31388001
Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription. PMID:31386698
Identifying miltefosine-resistant key genes in protein-protein interactions network and experimental verification in Iranian Leishmania major. PMID:31385238
C-Jun drives melanoma progression in PTEN wild type melanoma cells. PMID:31378787
Male Sterility in Maize after Transient Heat Stress during the Tetrad Stage of Pollen Development. PMID:31378720
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis. PMID:31371714
Myosin V regulates synaptopodin clustering and localization in the dendrites of hippocampal neurons. PMID:31371487
Clinical and Genetic Findings in Children with Neurofibromatosis Type 1, Legius Syndrome, and Other Related Neurocutaneous Disorders. PMID:31370276
The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States. PMID:31368393
Transcriptomic analysis to affirm the regulatory role of long non-coding RNA in horn cancer of Indian zebu cattle breed Kankrej (Bos indicus). PMID:31368028
Characteristic genes in THP‑1 derived macrophages infected with Mycobacterium tuberculosis H37Rv strain identified by integrating bioinformatics methods. PMID:31364746
HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer. PMID:31364281
Candidate genes and pathways associated with brain metastasis from lung cancer compared with lymph node metastasis. PMID:31363372
Identification of potential drug targets and vaccine candidates in Clostridium botulinum using subtractive genomics approach. PMID:31359994
Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion. PMID:31358880
Lack of long-term acclimation in Antarctic encrusting species suggests vulnerability to warming. PMID:31358752
Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype. PMID:31356623
Mammalian Annotation Database for improved annotation and functional classification of Omics datasets from less well-annotated organisms. PMID:31353404
m1A Regulated Genes Modulate PI3K/AKT/mTOR and ErbB Pathways in Gastrointestinal Cancer. PMID:31352195
Global view of the RAF-MEK-ERK module and its immediate downstream effectors. PMID:31350469
Infrapatellar fat pad-derived MSC response to inflammation and fibrosis induces an immunomodulatory phenotype involving CD10-mediated Substance P degradation. PMID:31350444
A Review of Bioinformatics Tools to Understand Acetaminophen-Alcohol Interaction. PMID:31349598
The Methods Employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein-Protein Interactions (PPIs). PMID:31347048
Identification and Interaction Analysis of Key Genes and MicroRNAs in Systemic Sclerosis by Bioinformatics Approaches. PMID:31347003
Integrated identification of key genes and pathways in Alzheimer's disease via comprehensive bioinformatical analyses. PMID:31346329
Identification and Interaction Analysis of Significant Genes and MicroRNAs in Pterygium. PMID:31341891
Beyond Synthetic Lethality: Charting the Landscape of Pairwise Gene Expression States Associated with Survival in Cancer. PMID:31340155
Identification of Gene Changes Induced by Dexamethasone in the Anterior Segment of the Human Eye Using Bioinformatics Analysis. PMID:31339875
Myricanol modulates skeletal muscle-adipose tissue crosstalk to alleviate high-fat diet-induced obesity and insulin resistance. PMID:31339170
Transcriptomic Responses of Skeletal Muscle to Acute Exercise in Diabetic Goto-Kakizaki Rats. PMID:31338039
ScCobB2-mediated Lysine Desuccinylation Regulates Protein Biosynthesis and Carbon Metabolism in Streptomyces coelicolor. PMID:31337674
Using deep maxout neural networks to improve the accuracy of function prediction from protein interaction networks. PMID:31335894
Neonatal Intermittent Hypoxia Induces Lasting Sex-Specific Augmentation of Rat Microglial Cytokine Expression. PMID:31333645
Insights about multi-targeting and synergistic neuromodulators in Ayurvedic herbs against epilepsy: integrated computational studies on drug-target and protein-protein interaction networks. PMID:31332210
The design, analysis and application of mouse clinical trials in oncology drug development. PMID:31331301
Network-Based Integrative Analysis of Genomics, Epigenomics and Transcriptomics in Autism Spectrum Disorders. PMID:31323926
High Functioning Autism with Missense Mutations in Synaptotagmin-Like Protein 4 (SYTL4) and Transmembrane Protein 187 (TMEM187) Genes: SYTL4- Protein Modeling, Protein-Protein Interaction, Expression Profiling and MicroRNA Studies. PMID:31323913
Genome-wide investigation of the clinical significance and prospective molecular mechanism of minichromosome maintenance protein family genes in patients with Lung Adenocarcinoma. PMID:31323040
DNA hypermethylation of aurora kinase A in hepatitis C virus‑positive hepatocellular carcinoma. PMID:31322223
Identification of differentially expressed genes in hip cartilage with femoral head necrosis, based on genome‑wide expression profiles. PMID:31322206
Chronic shisha exposure alters phosphoproteome of oral keratinocytes. PMID:31321732
Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism. PMID:31320750
Silencing of RAD51AP1 suppresses epithelial-mesenchymal transition and metastasis in non-small cell lung cancer. PMID:31317661
CAGI5: Objective performance assessments of predictions based on the Evolutionary Action equation. PMID:31317604
BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors. PMID:31316060
Analysis of the equine "cumulome" reveals major metabolic aberrations after maturation in vitro. PMID:31315563
The first evidence of global meat phosphoproteome changes in response to pre-slaughter stress. PMID:31315554
miRFA: an automated pipeline for microRNA functional analysis with correlation support from TCGA and TCPA expression data in pancreatic cancer. PMID:31311505
Systematic analysis of the lysine succinylome in the model medicinal mushroom Ganoderma lucidum. PMID:31311503
Inferring novel genes related to colorectal cancer via random walk with restart algorithm. PMID:31308477
PhenPath: a tool for characterizing biological functions underlying different phenotypes. PMID:31307376
Comprehensive analysis of an lncRNA-miRNA-mRNA competing endogenous RNA network in pulpitis. PMID:31304055
Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay. PMID:31300274
GEMINI: a variational Bayesian approach to identify genetic interactions from combinatorial CRISPR screens. PMID:31300006
Identification of potential key genes and pathways predicting pathogenesis and prognosis for triple-negative breast cancer. PMID:31297036
Protein interaction networks revealed by proteome coevolution. PMID:31296772
Comprehensive Gene Expression Analysis in NMIBC Using RNA-seq Reveals New Therapy Strategies. PMID:31293967
Ellagic acid exerts antitumor effects via the PI3K signaling pathway in endometrial cancer. PMID:31293633
Integrative multi-omic analysis identifies new drivers and pathways in molecularly distinct subtypes of ALS. PMID:31292500
Protein synthesis rates and ribosome occupancies reveal determinants of translation elongation rates. PMID:31292258
MCF-7 as a Model for Functional Analysis of Breast Cancer Risk Variants. PMID:31292138
Acute Iron Deprivation Reprograms Human Macrophage Metabolism and Reduces Inflammation In Vivo. PMID:31291584
GPCR-mediated PI3K pathway mutations in pediatric and adult thyroid cancer. PMID:31289610
Identification of microRNA-92a and the related combination biomarkers as promising substrates in predicting risk, recurrence and poor survival of colorectal cancer. PMID:31289586
Interactome Analysis and Docking Sites of MutS Homologs Reveal New Physiological Roles in Arabidopsis thaliana. PMID:31288414
Identification of five hub genes as monitoring biomarkers for breast cancer metastasis in silico. PMID:31285741
Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility. PMID:31285581
Bacterial MbtH-like Proteins Stimulate Nonribosomal Peptide Synthetase-Derived Secondary Metabolism in Filamentous Fungi. PMID:31284717
Genome-wide functional association networks: background, data & state-of-the-art resources. PMID:31281921
Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome. PMID:31281524
Identification of diagnostic markers for major depressive disorder by cross-validation of data from whole blood samples. PMID:31275757
Cancer driver genes: a guilty by resemblance doctrine. PMID:31275738
Whole Exome Sequencing Identified a Novel Biallelic SMARCAL1 Mutation in the Extremely Rare Disease SIOD. PMID:31275356
Chemoproteomic Method for Profiling Inhibitor-Bound Kinase Complexes. PMID:31274292
PGC-1a integrates a metabolism and growth network linked to caloric restriction. PMID:31267675
Cooperation Between the Inflammation and Coagulation Systems Promotes the Survival of Circulating Tumor Cells in Renal Cell Carcinoma Patients. PMID:31263677
GAIL: An interactive webserver for inference and dynamic visualization of gene-gene associations based on gene ontology guided mining of biomedical literature. PMID:31260503
Dissecting the expression landscape of cytochromes P450 in hepatocellular carcinoma: towards novel molecular biomarkers. PMID:31258835
Ginkgo biloba Extract Modulates the Retroperitoneal Fat Depot Proteome and Reduces Oxidative Stress in Diet-Induced Obese Rats. PMID:31258482
miRNA‑mRNA regulatory network analysis of mesenchymal stem cell treatment in cisplatin‑induced acute kidney injury identifies roles for miR‑210/Serpine1 and miR‑378/Fos in regulating inflammation. PMID:31257474
Identification of crucial miRNAs and lncRNAs for ossification of ligamentum flavum. PMID:31257472
Decoding the proteomic changes involved in the biofilm formation of Enterococcus faecalis SK460 to elucidate potential biofilm determinants. PMID:31253082
Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose. PMID:31253076
Inferring Interaction Networks From Multi-Omics Data. PMID:31249591
Transcriptome Profiling Reveals Pro-Inflammatory Cytokines and Matrix Metalloproteinase Activation in Zika Virus Infected Human Umbilical Vein Endothelial Cells. PMID:31249527
Protein-Protein interaction network analyses of human WNT proteins involved in neural development. PMID:31249432
NOTCH Activation Promotes Valve Formation by Regulating the Endocardial Secretome. PMID:31249105
Unveiling the Interplay between the TLR4/MD2 Complex and HSP70 in the Human Cardiovascular System: A Computational Approach. PMID:31247943
Transcriptome analysis reveals that fertilization with cryopreserved sperm downregulates genes relevant for early embryo development in the horse. PMID:31237882
In Silico Analysis of Coding/Noncoding SNPs of Human RETN Gene and Characterization of Their Impact on Resistin Stability and Structure. PMID:31236417
Mr.Vc: a database of microarray and RNA-seq of Vibrio cholerae. PMID:31231774
A quantitative Streptococcus pyogenes-human protein-protein interaction map reveals localization of opsonizing antibodies. PMID:31227708
Insights into Impact of DNA Copy Number Alteration and Methylation on the Proteogenomic Landscape of Human Ovarian Cancer via a Multi-omics Integrative Analysis. PMID:31227599
Partial defoliation of Brachypodium distachyon plants grown in petri dishes under low light increases P and other nutrient levels concomitantly with transcriptional changes in the roots. PMID:31223535
Systems-level Analysis Reveals Multiple Modulators of Epithelial-mesenchymal Transition and Identifies DNAJB4 and CD81 as Novel Metastasis Inducers in Breast Cancer. PMID:31221721
Identification of microRNAs and genes as biomarkers of atrial fibrillation using a bioinformatics approach. PMID:31218935
Dysregulation in the Brain Protein Profile of Zebrafish Lacking the Parkinson's Disease-Related Protein DJ-1. PMID:31218647
Altered Gene Expression of Thyroid Hormone Transporters and Deiodinases in iPS MeCP2-Knockout Cells-Derived Neurons. PMID:31214863
Characterization of Protein Profiling and mRNA Expression of LLC Exosomes. PMID:31214853
Proestrus Differentially Regulates Expression of Ion Channel and Calcium Homeostasis Genes in GnRH Neurons of Mice. PMID:31213979
The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis. PMID:31211768
Efficacy of copolymer scaffolds delivering human demineralised dentine matrix for bone regeneration. PMID:31210921
Chromogranin-A Expression as a Novel Biomarker for Early Diagnosis of Colon Cancer Patients. PMID:31207989
Hypoxia Regulated Gene Network in Glioblastoma Has Special Algebraic Topology Structures and Revealed Communications Involving Warburg Effect and Immune Regulation. PMID:31203532
Allele Loss and Reduced Expression of CYCLOPS Genes is a Characteristic Feature of Chromophobe Renal Cell Carcinoma. PMID:31200327
Ouabain-regulated phosphoproteome reveals molecular mechanisms for Na+, K+-ATPase control of cell adhesion, proliferation, and survival. PMID:31199885
Trouble is coming: Signaling pathways that regulate general stress responses in bacteria. PMID:31197038
Synovial fluid biomarkers associated with osteoarthritis severity reflect macrophage and neutrophil related inflammation. PMID:31196179
Identification of key genes and pathways in seminoma by bioinformatics analysis. PMID:31190870
Identification of novel biomarkers and candidate small molecule drugs in non-small-cell lung cancer by integrated microarray analysis. PMID:31190860
Caveolin1 interacts with the glucocorticoid receptor in the lung but is dispensable for its anti-inflammatory actions in lung inflammation and Trichuris Muris infection. PMID:31189975
Overexpression of miRNA-25-3p inhibits Notch1 signaling and TGF-β-induced collagen expression in hepatic stellate cells. PMID:31189969
Tissue-Specific Gene Expression during Productive Human Papillomavirus 16 Infection of Cervical, Foreskin, and Tonsil Epithelium. PMID:31189705
A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism. PMID:31189117
Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer. PMID:31189116
RNA sequencing uncovers the key long non-coding RNAs and potential molecular mechanism contributing to XAV939-mediated inhibition of non-small cell lung cancer. PMID:31186710
The initiation of puberty in Atlantic salmon brings about large changes in testicular gene expression that are modulated by the energy status. PMID:31185904
Multiomics Analyses of HNF4α Protein Domain Function during Human Pluripotent Stem Cell Differentiation. PMID:31185456
Integrated Bioinformatics Analysis of Master Regulators in Anaplastic Thyroid Carcinoma. PMID:31183379
A novel lncRNA-miRNA-mRNA triple network identifies lncRNA TWF1 as an important regulator of miRNA and gene expression in coronary artery disease. PMID:31182968
Combining an in silico approach with an animal experiment to investigate the protective effect of troxerutin for treating acute lung injury. PMID:31182097
Genetic resistance to DEHP-induced transgenerational endocrine disruption. PMID:31181066
Bioinformatics analysis of the regulatory lncRNA‑miRNA‑mRNA network and drug prediction in patients with hypertrophic cardiomyopathy. PMID:31180540
RNA‑seq analyses of antibiotic resistance mechanisms in Serratia marcescens. PMID:31180518
Identify CRNDE and LINC00152 as the key lncRNAs in age-related degeneration of articular cartilage through comprehensive and integrative analysis. PMID:31179196
Weighted gene coexpression network analysis reveals hub genes involved in cholangiocarcinoma progression and prognosis. PMID:31177590
Identification of Key Genes and Pathway for Ovarian Neoplasms Using the OVDM1 Cell Line Based on Bioinformatics Analysis. PMID:31177266
Identification of key candidate genes involved in melanoma metastasis. PMID:31173190
Identification of core genes and clinical roles in pregnancy-associated breast cancer based on integrated analysis of different microarray profile datasets. PMID:31171715
SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. PMID:31171447
Overexpression of microRNA-195-5p reduces cisplatin resistance and angiogenesis in ovarian cancer by inhibiting the PSAT1-dependent GSK3β/β-catenin signaling pathway. PMID:31171023
Endometriosis Knowledgebase: a gene-based resource on endometriosis. PMID:31169291
STRIPAK Members Orchestrate Hippo and Insulin Receptor Signaling to Promote Neural Stem Cell Reactivation. PMID:31167138
Identification of key modules and hub genes for small-cell lung carcinoma and large-cell neuroendocrine lung carcinoma by weighted gene co-expression network analysis of clinical tissue-proteomes. PMID:31166966
Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma. PMID:31160565
Investigating the dysfunctional pathogenesis of Wilms' tumor through a multidimensional integration strategy. PMID:31157257
A targeted proteomics approach reveals a serum protein signature as diagnostic biomarker for resectable gastric cancer. PMID:31151932
Cmah deficiency may lead to age-related hearing loss by influencing miRNA-PPAR mediated signaling pathway. PMID:31149396
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. PMID:31144443
Maize transcriptomic repertoires respond to gibberellin stimulation. PMID:31144186
Combined cellomics and proteomics analysis reveals shared neuronal morphology and molecular pathway phenotypes for multiple schizophrenia risk genes. PMID:31142819
Runx2 stimulates neoangiogenesis through the Runt domain in melanoma. PMID:31142788
Combined Scaffold Evaluation and Systems-Level Transcriptome-Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes. PMID:31140738
[Bioinformatics analysis of COL1A1 regulated by miR-129-5p as a potential therapeutic target for gastric cancer]. PMID:31140417
Significance of PTEN Mutation in Cellular Process, Prognosis, and Drug Selection in Clear Cell Renal Cell Carcinoma. PMID:31139560
Eleven genes associated with progression and prognosis of endometrial cancer (EC) identified by comprehensive bioinformatics analysis. PMID:31139013
Identify differential gene expressions in fatty infiltration process in rotator cuff. PMID:31138249
Comprehensive analysis of key genes and microRNAs in radioresistant nasopharyngeal carcinoma. PMID:31138194
NECTIN4 (PVRL4) as Putative Therapeutic Target for a Specific Subtype of High Grade Serous Ovarian Cancer-An Integrative Multi-Omics Approach. PMID:31137558
Identification of Hub Genes Associated With Progression and Prognosis in Patients With Bladder Cancer. PMID:31134129
FN1, SPARC, and SERPINE1 are highly expressed and significantly related to a poor prognosis of gastric adenocarcinoma revealed by microarray and bioinformatics. PMID:31127138
Potential Molecular Mechanisms of AURKB in the Oncogenesis and Progression of Osteosarcoma Cells: A Label-Free Quantitative Proteomics Analysis. PMID:31122179
An In-Depth View of the Porcine Trabecular Meshwork Proteome. PMID:31121981
Gene shaving using a sensitivity analysis of kernel based machine learning approach, with applications to cancer data. PMID:31120939
Identification of Potential Biomarkers in Glioblastoma through Bioinformatic Analysis and Evaluating Their Prognostic Value. PMID:31119182
Cold acclimation triggers major transcriptional changes in Drosophila suzukii. PMID:31117947
Identification of a transcription factor-microRNA network in esophageal adenocarcinoma through bioinformatics analysis and validation through qRT-PCR. PMID:31114367
RNAseq Profiling of Leukocyte Populations in Zebrafish Larvae Reveals a cxcl11 Chemokine Gene as a Marker of Macrophage Polarization During Mycobacterial Infection. PMID:31110502
Proteomic and Metabolomic Profiling of Deinococcus radiodurans Recovering After Exposure to Simulated Low Earth Orbit Vacuum Conditions. PMID:31110498
Exploring the use of molecular dynamics in assessing protein variants for phenotypic alterations. PMID:31106920
A novel conserved family of Macro-like domains-putative new players in ADP-ribosylation signaling. PMID:31106069
Identification and comparative analysis of the CIPK gene family and characterization of the cold stress response in the woody plant Prunus mume. PMID:31106064
Genomic landscape analyses of reprogrammed cells using integrative and non-integrative methods reveal variable cancer-associated alterations. PMID:31105870
Deregulation of a Network of mRNA and miRNA Genes Reveals That CK2 and MEK Inhibitors May Synergize to Induce Apoptosis KRAS-Active NSCLC. PMID:31105425
Use of Genome-Scale Integrated Analysis to Identify Key Genes and Potential Molecular Mechanisms in Recurrence of Lower-Grade Brain Glioma. PMID:31104065
Low-dose aspirin protective effects are correlated with deregulation of HNF factor expression in the preeclamptic placentas from mice and humans. PMID:31098302
Computational identification of tissue-specific transcription factor cooperation in ten cattle tissues. PMID:31095599
Identification of novel biomarkers and small molecule drugs in human colorectal cancer by microarray and bioinformatics analysis. PMID:31087508
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus. PMID:31086297
Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity. PMID:31080084
R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation. PMID:31076284
Human Mitotic Centromere-Associated Kinesin Is Targeted by MicroRNA 485-5p/181c and Prognosticates Poor Survivability of Breast Cancer. PMID:31073307
What lies beneath? Molecular evolution during the radiation of caecilian amphibians. PMID:31072350
Elevated CCL19/CCR7 Expression During the Disease Process of Primary Sjögren's Syndrome. PMID:31068931
A longitudinal big data approach for precision health. PMID:31068711
Next-generation characterization of the Cancer Cell Line Encyclopedia. PMID:31068700
A Comprehensive Bioinformatics Analysis of UBE2C in Cancers. PMID:31067633
Plasma protein biomarkers and their association with mutually exclusive cardiovascular phenotypes: the FIBRO-TARGETS case-control analyses. PMID:31062082
Target Gene Prediction of Transcription Factor Using a New Neighborhood-regularized Tri-factorization One-class Collaborative Filtering Algorithm. PMID:31061989
RNA sequencing of mesenchymal stem cells reveals a blocking of differentiation and immunomodulatory activities under inflammatory conditions in rheumatoid arthritis patients. PMID:31060598
Using RNA-seq to characterize responses to 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor herbicide resistance in waterhemp (Amaranthus tuberculatus). PMID:31060501
Quantitative Proteomics Identifies DNA Repair as a Novel Biological Function for Hepatocyte Nuclear Factor 4α in Colorectal Cancer Cells. PMID:31060309
Meta-analysis of drought-tolerant genotypes in Oryza sativa: A network-based approach. PMID:31059518
Bioinformatics identification of lncRNA biomarkers associated with the progression of esophageal squamous cell carcinoma. PMID:31059058
Screening of underlying genetic biomarkers for ankylosing spondylitis. PMID:31059041
miR‑148 family members are putative biomarkers for sepsis. PMID:31059023
ALK4/5-dependent TGF-β signaling contributes to the crosstalk between neurons and microglia following axonal lesion. PMID:31053759
Polysome Profiling of a Human Glioblastoma Reveals Intratumoral Heterogeneity. PMID:31052505
Genes with High Network Connectivity Are Enriched for Disease Heritability. PMID:31051114
Whole transcriptome sequencing identifies crucial genes associated with colon cancer and elucidation of their possible mechanisms of action. PMID:31043791
Up-regulation of tumor necrosis factor-α pathway survival genes and of the receptor TNFR2 in gastric cancer. PMID:31040894
IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells. PMID:31040842
The Identification of Potential Biomarkers and Biological Pathways in Prostate Cancer. PMID:31031850
Experimental Analysis of Viral-Host Interactions. PMID:31031644
Triggering MSR1 promotes JNK-mediated inflammation in IL-4-activated macrophages. PMID:31028084
Preeclampsia is Associated with Sex-Specific Transcriptional and Proteomic Changes in Fetal Erythroid Cells. PMID:31027199
A Major Root Architecture QTL Responding to Water Limitation in Durum Wheat. PMID:31024600
Brain Citrullination Patterns and T Cell Reactivity of Cerebrospinal Fluid-Derived CD4+ T Cells in Multiple Sclerosis. PMID:31024521
An Open Science Approach to Artificial Intelligence in Healthcare. PMID:31022753
Systematic identification of key genes and pathways in clear cell renal cell carcinoma on bioinformatics analysis. PMID:31019939
Identifying Critical State of Complex Diseases by Single-Sample-Based Hidden Markov Model. PMID:31019526
Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer's disease. PMID:31019427
Treatment of Common Sunflower (Helianthus annus L.) Seeds with Radio-frequency Electromagnetic Field and Cold Plasma Induces Changes in Seed Phytohormone Balance, Seedling Development and Leaf Protein Expression. PMID:31015543
In silico learning of tumor evolution through mutational time series. PMID:31015295
How RNAi machinery enters the world of telomerase. PMID:31014212
Equine Adipose-Derived Mesenchymal Stromal Cells Release Extracellular Vesicles Enclosing Different Subsets of Small RNAs. PMID:31011332
p-21 Activated Kinase as a Molecular Target for Chemoprevention in Diabetes. PMID:31011108
Identification of significant genes with poor prognosis in ovarian cancer via bioinformatical analysis. PMID:31010415
Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development. PMID:31004009
Prediction of Recurrence in Cervical Cancer Using a Nine-lncRNA Signature. PMID:31001325
Application of a Sensitive and Reproducible Label-Free Proteomic Approach to Explore the Proteome of Individual Meiotic-Phase Barley Anthers. PMID:31001307
Genotoxicity of zinc oxide nanoparticles: an in vivo and in silico study. PMID:30997027
A Six-Gene-Based Prognostic Model Predicts Survival in Head and Neck Squamous Cell Carcinoma Patients. PMID:30996559
Analysis of the In Vivo Transcriptome of Bordetella pertussis during Infection of Mice. PMID:30996109
Phosphoproteomic Analysis of Two Contrasting Maize Inbred Lines Provides Insights into the Mechanism of Salt-Stress Tolerance. PMID:30995804
Analysis of cyclin E co-expression genes reveals nuclear transcription factor Y subunit alpha is an oncogene in gastric cancer. PMID:30993263
Identification of key pathways and genes in nasopharyngeal carcinoma using bioinformatics analysis. PMID:30988824
Bioinformatics analysis of microRNA expression between patients with and without latent tuberculosis infections. PMID:30988779
ITLNI identified by comprehensive bioinformatic analysis as a hub candidate biological target in human epithelial ovarian cancer. PMID:30988639
The role of IRAK1 in breast cancer patients treated with neoadjuvant chemotherapy. PMID:30988621
Genes CEP55, FOXD3, FOXF2, GNAO1, GRIA4, and KCNA5 as potential diagnostic biomarkers in colorectal cancer. PMID:30987631
Isotopic Labeling and Quantitative Proteomics of Acetylation on Histones and Beyond. PMID:30980322
A network of human functional gene interactions from knockout fitness screens in cancer cells. PMID:30979825
ULK1 and ULK2 Regulate Stress Granule Disassembly Through Phosphorylation and Activation of VCP/p97. PMID:30979586
Combinatorial Detection of Conserved Alteration Patterns for Identifying Cancer Subnetworks. PMID:30978274
FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells. PMID:30973875
Novel insights into gene expression regulation during meiosis revealed by translation elongation dynamics. PMID:30962948
Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children. PMID:30962590
Phytanoyl-CoA 2-Hydroxylase-Interacting Protein-Like Gene Is a Therapeutic Target Gene for Glioblastoma Multiforme. PMID:30962415
Integrated analysis of gene expression changes associated with coronary artery disease. PMID:30961613
SAMHD1 Enhances Chikungunya and Zika Virus Replication in Human Skin Fibroblasts. PMID:30959732
Identification of lncRNAs associated with early-stage breast cancer and their prognostic implications. PMID:30959550
Downregulation of CENPF Remodels Prostate Cancer Cells and Alters Cellular Metabolism. PMID:30957416
Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression. PMID:30955890
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. PMID:30955884
exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids. PMID:30951672
Unveiling the Kinomes of Leishmania infantum and L. braziliensis Empowers the Discovery of New Kinase Targets and Antileishmanial Compounds. PMID:30949306
Identification of Key Genes and Circular RNAs in Human Gastric Cancer. PMID:30948703
The Alzheimer's comorbidity phenome: mining from a large patient database and phenome-driven genetics prediction. PMID:30944912
Candidate genes and potential mechanisms for chemoradiotherapy sensitivity in locally advanced rectal cancer. PMID:30944639
Novel Genetic Locus of Visceral Fat and Systemic Inflammation. PMID:30942860
Identification of the Biomarkers and Pathological Process of Osteoarthritis: Weighted Gene Co-expression Network Analysis. PMID:30941059
Fetal lung C4BPA induces p100 processing in human placenta. PMID:30940885
Data Mining and Validation of AMPK Pathway as a Novel Candidate Role Affecting Intramuscular Fat Content in Pigs. PMID:30939765
Identification of Candidate Genes and Pathways in Dexmedetomidine-Induced Cardioprotection in the Rat Heart by Bioinformatics Analysis. PMID:30939728
Identification of SERPINE1, PLAU and ACTA1 as biomarkers of head and neck squamous cell carcinoma based on integrated bioinformatics analysis. PMID:30937621
Williams Syndrome, Human Self-Domestication, and Language Evolution. PMID:30936846
Saliva MicroRNA Differentiates Children With Autism From Peers With Typical and Atypical Development. PMID:30926572
Combinatorial interactions of genetic variants in human cardiomyopathy. PMID:30923642
High olive oil diets enhance cervical tumour growth in mice: transcriptome analysis for potential candidate genes and pathways. PMID:30922331
Identification of gene-phenotype connectivity associated with flavanone naringenin by functional network analysis. PMID:30918758
Adapting Community Detection Algorithms for Disease Module Identification in Heterogeneous Biological Networks. PMID:30918511
Prioritization of potential vaccine targets using comparative proteomics and designing of the chimeric multi-epitope vaccine against Pseudomonas aeruginosa. PMID:30918289
Effects of early social deprivation on epigenetic statuses and adaptive behavior of young children: A study based on a cohort of institutionalized infants and toddlers. PMID:30913238
Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets. PMID:30912767
Long non-coding RNA SNHG6 is upregulated in prostate cancer and predicts poor prognosis. PMID:30911973
RNA-sequencing in ophthalmology research: considerations for experimental design and analysis. PMID:30911735
Targeting ELTD1, an angiogenesis marker for glioblastoma (GBM), also affects VEGFR2: molecular-targeted MRI assessment. PMID:30911439
Molecular Players of EF-hand Containing Calcium Signaling Event in Plants. PMID:30909616
Construction and Analysis of Protein-Protein Interaction Network of Heroin Use Disorder. PMID:30899073
Comparative proteomic study reveals the enhanced immune response with the blockade of interleukin 10 with anti-IL-10 and anti-IL-10 receptor antibodies in human U937 cells. PMID:30897137
Genome-scale integrated analysis to identify prospective molecular mechanisms and therapeutic targets in isocitrate dehydrogenase 2 R140Q-mutated acute myeloid leukemia. PMID:30896832
An lncRNA‑miRNA‑mRNA ceRNA network for adipocyte differentiation from human adipose‑derived stem cells. PMID:30896814
Silencing the lncRNA Maclpil in pro-inflammatory macrophages attenuates acute experimental ischemic stroke via LCP1 in mice. PMID:30895879
Diet Induced Obesity Alters Intestinal Cytoplasmic Lipid Droplet Morphology and Proteome in the Postprandial Response to Dietary Fat. PMID:30890954
Identification of Gene Expression Changes Associated With Uterine Receptivity in Mice. PMID:30890945
Identification of four hub genes associated with adrenocortical carcinoma progression by WGCNA. PMID:30886771
Network-based prediction of protein interactions. PMID:30886144
SNP mutation-related genes in breast cancer for monitoring and prognosis of patients: A study based on the TCGA database. PMID:30883028
Villi development core-related gene expression associated with lung squamous cancer prognosis. PMID:30882635
Predicting MicroRNA Target Genes and Identifying Hub Genes in IIA Stage Colon Cancer Patients Using Bioinformatics Analysis. PMID:30881993
Identification of Important Effector Proteins in the FOXJ1 Transcriptional Network Associated With Ciliogenesis and Ciliary Function. PMID:30881373
RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma. PMID:30881024
Long Noncoding RNA and Protein Interactions: From Experimental Results to Computational Models Based on Network Methods. PMID:30875752
Analyzing bioactive effects of the minor hop compound xanthohumol C on human breast cancer cells using quantitative proteomics. PMID:30875365
Comprehensive analysis of the GATA transcription factor gene family in breast carcinoma using gene microarrays, online databases and integrated bioinformatics. PMID:30872657
Regulation of proline-directed kinases and the trans-histone code H3K9me3/H4K20me3 during human myogenesis. PMID:30872405
Multiomics Analysis Reveals that GLS and GLS2 Differentially Modulate the Clinical Outcomes of Cancer. PMID:30871151
Identification of differentially expressed key genes between glioblastoma and low-grade glioma by bioinformatics analysis. PMID:30867991
Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs). PMID:30867899
Herb Target Prediction Based on Representation Learning of Symptom related Heterogeneous Network. PMID:30867892
Circulating proteomic panels for diagnosis and risk stratification of acute-on-chronic liver failure in patients with viral hepatitis B. PMID:30867825
Crosstalk analysis of dysregulated pathways in preeclampsia. PMID:30867714
Meta-analysis suggests evidence of novel stress-related pathway components in Orsay virus - Caenorhabditis elegans viral model. PMID:30867481
Multiomics analysis profile acute liver injury module clusters to compare the therapeutic efficacy of bifendate and muaddil sapra. PMID:30867448
Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes. PMID:30865899
Identification of hub genes in chronically hypoxic myocardium using bioinformatics analysis. PMID:30864710
Proteomics profiling of plasma exosomes in epithelial ovarian cancer: A potential role in the coagulation cascade, diagnosis and prognosis. PMID:30864689
Outgroup Machine Learning Approach Identifies Single Nucleotide Variants in Noncoding DNA Associated with Autism Spectrum Disorder. PMID:30864328
Amorphous silica nanoparticles induce tumorigenesis via regulating ATP5H/SOD1-related oxidative stress, oxidative phosphorylation and EIF4G2/PABPC1-associated translational initiation. PMID:30863671
Identification of key pathways and hub genes in basal-like breast cancer using bioinformatics analysis. PMID:30863098
Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy. PMID:30858180
Comparative transcriptome analysis uncovers the regulatory functions of long noncoding RNAs in fruit development and color changes of Fragaria pentaphylla. PMID:30854215
What makes turnips: anatomy, physiology and transcriptome during early stages of its hypocotyl-tuber development. PMID:30854213
Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia- and Alzheimer's-associated amyloid beta peptide. PMID:30850528
Identification of Potential Candidate Genes of Oral Cancer in Response to Chronic Infection With Porphyromonas gingivalis Using Bioinformatical Analyses. PMID:30847302
Network Pharmacology Databases for Traditional Chinese Medicine: Review and Assessment. PMID:30846939
Integrated DNA methylation and gene expression analysis in the pathogenesis of coronary artery disease. PMID:30844764
Seasonal variation in equine follicular fluid proteome. PMID:30841911
Transcriptomics analysis of propiconazole-treated Cochliobolus sativus reveals new putative azole targets in the plant pathogen. PMID:30840164
Reconstruction and Functional Annotation of P311 Protein-Protein Interaction Network Reveals Its New Functions. PMID:30838032
Genome-Wide Association Study for Milk Protein Composition Traits in a Chinese Holstein Population Using a Single-Step Approach. PMID:30838020
A Comparative Study of Cluster Detection Algorithms in Protein-Protein Interaction for Drug Target Discovery and Drug Repurposing. PMID:30837876
Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton. PMID:30837512
Classification of the human THAP protein family identifies an evolutionarily conserved coiled coil region. PMID:30836974
Transcriptome and Proteome-Based Network Analysis Reveals a Model of Gene Activation in Wheat Resistance to Stripe Rust. PMID:30836695
Proteomic Analysis of Arabidopsis pldα1 Mutants Revealed an Important Role of Phospholipase D Alpha 1 in Chloroplast Biogenesis. PMID:30833950
miR-132 suppresses transcription of ribosomal proteins to promote protective Th1 immunity. PMID:30833344
The Epstein-Barr virus EBNA1 protein modulates the alternative splicing of cellular genes. PMID:30832682
Down-regulation of microRNA-144-3p and its clinical value in non-small cell lung cancer: a comprehensive analysis based on microarray, miRNA-sequencing, and quantitative real-time PCR data. PMID:30832674
Cell type-specific immune phenotypes predict loss of insulin secretion in new-onset type 1 diabetes. PMID:30830868
New insights into host adaptation to swine respiratory disease revealed by genetic differentiation and RNA sequencing analyses. PMID:30828372
Genomic Variations in Susceptibility to Intracranial Aneurysm in the Korean Population. PMID:30823506
Comprehensive Analysis of the Chitinase Family Genes in Tomato (Solanum lycopersicum). PMID:30823433
Prediction of itching diagnostic marker through RNA sequencing of contact hypersensitivity and skin scratching stimulation mice models. PMID:30820159
Far-infrared radiation stimulates platelet-derived growth factor mediated skeletal muscle cell migration through extracellular matrix-integrin signaling. PMID:30820158
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. PMID:30820047
Transcriptome analysis reveals regulatory framework for salt and osmotic tolerance in a succulent xerophyte. PMID:30819118
Reconstruction and analysis of circRNA‑miRNA‑mRNA network in the pathology of cervical cancer. PMID:30816541
Identification of key genes and pathways contributing to artery tertiary lymphoid organ development in advanced mouse atherosclerosis. PMID:30816519
Identification of survival‑associated key genes and long non‑coding RNAs in glioblastoma multiforme by weighted gene co‑expression network analysis. PMID:30816427
Analysis of Predicted Host-Parasite Interactomes Reveals Commonalities and Specificities Related to Parasitic Lifestyle and Tissues Tropism. PMID:30815000
Comparative Phosphoproteomic Profiling of Type III Adenylyl Cyclase Knockout and Control, Male, and Female Mice. PMID:30814930
Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes. PMID:30814566
Identifying Windows of Susceptibility by Temporal Gene Analysis. PMID:30809014
Circadian regulation in human white adipose tissue revealed by transcriptome and metabolic network analysis. PMID:30804433
Synergistic lethality between BRCA1 and H3K9me2 loss reflects satellite derepression. PMID:30804228
Motion sensing superpixels (MOSES) is a systematic computational framework to quantify and discover cellular motion phenotypes. PMID:30803483
Magic roundabout is an endothelial-specific ohnolog of ROBO1 which neo-functionalized to an essential new role in angiogenesis. PMID:30802244
Molecular cloning and characterization of six defensin genes from lentil plant (Lens culinaris L.). PMID:30800615
Combined analysis of dissimilar promoter accessibility and gene expression profiles identifies tissue-specific genes and actively repressed networks. PMID:30795793
IQGAP1, AmotL2, and FKBP51 Scaffoldins in the Glioblastoma Microenvironment. PMID:30794467
The promising novel biomarkers and candidate small molecule drugs in kidney renal clear cell carcinoma: Evidence from bioinformatics analysis of high-throughput data. PMID:30793530
Molecular origin of AuNPs-induced cytotoxicity and mechanistic study. PMID:30792478
MALAT1/miR-15b-5p/MAPK1 mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic heart disease via mTOR signaling pathway. PMID:30787203
Metabolism as an early predictor of DPSCs aging. PMID:30778087
BAP1 haploinsufficiency predicts a distinct immunogenic class of malignant peritoneal mesothelioma. PMID:30777124
Identification of novel candidate indicators for assessing zinc status during pregnancy in mice from microarray data. PMID:30770772
Investigating Common Pathogenic Mechanisms between Homo sapiens and Different Strains of Candida albicans for Drug Design: Systems Biology Approach via Two-Sided NGS Data Identification. PMID:30769958
Molecular Evolution of the Vacuolar Iron Transporter (VIT) Family Genes in 14 Plant Species. PMID:30769903
Protein Network Analysis of the Serum and Their Functional Implication in Patients Subjected to Traumatic Brain Injury. PMID:30766469
Phosphoproteomic analyses of kidneys of Atlantic salmon infected with Aeromonas salmonicida. PMID:30765835
Predicting Gene Ontology Function of Human MicroRNAs by Integrating Multiple Networks. PMID:30761178
The Old and the New: Discovery Proteomics Identifies Putative Novel Seminal Fluid Proteins in Drosophila. PMID:30760537
Bioinformatic gene analysis for potential biomarkers and therapeutic targets of atrial fibrillation-related stroke. PMID:30760287
Identification and characterization of genes with absolute mRNA abundances changes in tumor cells with varied transcriptome sizes. PMID:30760197
PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq. PMID:30759402
Identification of critical genes associated with spinal cord injury based on the gene expression profile of spinal cord tissues from trkB.T1 knockout mice. PMID:30747207
A network biology approach to unraveling inherited axonopathies. PMID:30737464
Coordination between TGF-β cellular signaling and epigenetic regulation during epithelial to mesenchymal transition. PMID:30736855
Analyzing a co-occurrence gene-interaction network to identify disease-gene association. PMID:30736752
RNA-Seq Transcriptome Profiling of the Queen Scallop (Aequipecten opercularis) Digestive Gland after Exposure to Domoic Acid-Producing Pseudo-nitzschia. PMID:30736356
Functional random forest with applications in dose-response predictions. PMID:30733524
Regional protein expression in human Alzheimer's brain correlates with disease severity. PMID:30729181
Plasmodium falciparum specific helicase 2 is a dual, bipolar helicase and is crucial for parasite growth. PMID:30728406
Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling. PMID:30723174
The effect of physiological stretch and the valvular endothelium on mitral valve proteomes. PMID:30722697
Comparative transcriptome analysis of mammary epithelial cells at different stages of lactation reveals wide differences in gene expression and pathways regulating milk synthesis between Jersey and Kashmiri cattle. PMID:30721247
Comprehensive bioinformatics analysis of critical lncRNAs, mRNAs and miRNAs in non‑alcoholic fatty liver disease. PMID:30720100
High Expression Levels of AGGF1 and MFAP4 Predict Primary Platinum-Based Chemoresistance and are Associated with Adverse Prognosis in Patients with Serous Ovarian Cancer. PMID:30719133
Mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes. PMID:30718334
Recent Insights into NCL Protein Function Using the Model Organism Dictyostelium discoideum. PMID:30717401
Placental CX3CL1 is Deregulated by Angiotensin II and Contributes to a Pro-Inflammatory Trophoblast-Monocyte Interaction. PMID:30717334
LOX and ACSL5 as potential relapse markers for pancreatic cancer patients. PMID:30712446
Upregulation of miR-200a and miR-204 in MPP+ -treated differentiated PC12 cells as a model of Parkinson's disease. PMID:30712312
Risk gene-set and pathways in 22q11.2 deletion-related schizophrenia: a genealogical molecular approach. PMID:30710087
Conserved regulation of RNA processing in somatic cell reprogramming. PMID:30704403
Identification of Early Salinity Stress-Responsive Proteins in Dunaliella salina by isobaric tags for relative and absolute quantitation (iTRAQ)-Based Quantitative Proteomic Analysis. PMID:30704074
Whole Genome Messenger RNA Profiling Identifies a Novel Signature to Predict Gastric Cancer Survival. PMID:30702489
Network Analysis Reveals TNF as a Major Hub of Reactive Inflammation Following Spinal Cord Injury. PMID:30700814
Physiological and iTRAQ-based proteomic analyses reveal the function of exogenous γ-aminobutyric acid (GABA) in improving tea plant (Camellia sinensis L.) tolerance at cold temperature. PMID:30700249
Regulatory Network and Prognostic Effect Investigation of PIP4K2A in Leukemia and Solid Cancers. PMID:30697230
Integrated analysis of lncRNA-associated ceRNA network reveals potential biomarkers for the prognosis of hepatitis B virus-related hepatocellular carcinoma. PMID:30697079
The increase of photosynthetic carbon assimilation as a mechanism of adaptation to low temperature in Lotus japonicus. PMID:30696867
S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy. PMID:30696811
Global Transcriptional Insights of Pollen-Pistil Interactions Commencing Self-Incompatibility and Fertilization in Tea [Camellia sinensis (L.) O. Kuntze]. PMID:30696008
Fibroblast activation and abnormal extracellular matrix remodelling as common hallmarks in three cancer-prone genodermatoses. PMID:30693469
Whole Exome Sequencing Identifies a Novel Pathogenic RET Variant in Hirschsprung Disease. PMID:30693022
Clinical trials, progression-speed differentiating features and swiftness rule of the innovative targets of first-in-class drugs. PMID:30689717
Off-target based drug repurposing opportunities for tivantinib in acute myeloid leukemia. PMID:30679640
Proteome-wide, Structure-Based Prediction of Protein-Protein Interactions/New Molecular Interactions Viewer. PMID:30679268
Molecular Mechanism of Cancer Susceptibility Associated with Fok1 Single Nucleotide Polymorphism of VDR in Relation to Breast Cancer. PMID:30678432
From Genotype to Phenotype: Through Chromatin. PMID:30678090
The Importance of Physioxia in Mesenchymal Stem Cell Chondrogenesis and the Mechanisms Controlling Its Response. PMID:30678074
INDETERMINATE-DOMAIN 4 (IDD4) coordinates immune responses with plant-growth in Arabidopsis thaliana. PMID:30677094
Genetic and genomic analyses of testicular hypoplasia in Nellore cattle. PMID:30677076
Intronic CNVs and gene expression variation in human populations. PMID:30677042
Integrative analysis of gene expression profiles reveals distinct molecular characteristics in oral tongue squamous cell carcinoma. PMID:30675303
Genome-wide identification and characterization of CKIN/SnRK gene family in Chlamydomonas reinhardtii. PMID:30674892
Thymidine phosphorylase promotes malignant progression in hepatocellular carcinoma through pentose Warburg effect. PMID:30674871
Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing. PMID:30674726
Characterization of the Sinorhizobium meliloti HslUV and ClpXP Protease Systems in Free-Living and Symbiotic States. PMID:30670545
Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap. PMID:30664679
Global Proteomic and Methylome Analysis in Human Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affecting Proper Innate Immune Response Signaling. PMID:30664289
Bioinformatics analysis of sex differences in arrhythmogenic right ventricular cardiomyopathy. PMID:30664203
Identification of key genes and pathways involved in microsatellite instability in colorectal cancer. PMID:30664178
EFNB2 acts as the target of miR-557 to facilitate cell proliferation, migration and invasion in pancreatic ductal adenocarcinoma by bioinformatics analysis and verification. PMID:30662604
G-Protein-Coupled Receptor 5 (LGR5) Overexpression Activates β-Catenin Signaling in Breast Cancer Cells via Protein Kinase A. PMID:30662060
Co-localization of genomic regions associated with seed morphology and composition in a desi chickpea (Cicer arietinum L.) population varying in seed protein concentration. PMID:30661107
VCAN Canonical Splice Site Mutation is Associated With Vitreoretinal Degeneration and Disrupts an MMP Proteolytic Site. PMID:30657523
Identification of dysregulated microRNAs in canine malignant melanoma. PMID:30655868
Identification of hub genes and pathways in glioblastoma by bioinformatics analysis. PMID:30655863
Identification of potential genes and pathways for response prediction of neoadjuvant chemoradiotherapy in patients with rectal cancer by systemic biological analysis. PMID:30655792
Identification of core genes and prediction of miRNAs associated with osteoporosis using a bioinformatics approach. PMID:30655789
Investigation of the clinical significance and molecular mechanism of miR-21-5p in hepatocellular carcinoma: A systematic review based on 24 studies and bioinformatics investigation. PMID:30655760
Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer. PMID:30652415
An in silico structural, functional and phylogenetic analysis with three dimensional protein modeling of alkaline phosphatase enzyme of Pseudomonas aeruginosa. PMID:30647696
Identification of hub genes and outcome in colon cancer based on bioinformatics analysis. PMID:30643458
Translation control of the immune checkpoint in cancer and its therapeutic targeting. PMID:30643286
Investigation of the Underlying Genes and Mechanism of Macrophage-Enriched Ruptured Atherosclerotic Plaques Using Bioinformatics Method. PMID:30643084
Complex-centric proteome profiling by SEC-SWATH-MS. PMID:30642884
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2. PMID:30639242
Inhibitor of DNA-Binding/Differentiation Proteins and Environmental Toxicants: Genomic Impact on the Onset of Depressive Dysfunction. PMID:30634536
Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. PMID:30633903
Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling. PMID:30632963
Clustering of Tau fibrils impairs the synaptic composition of α3-Na+/K+-ATPase and AMPA receptors. PMID:30630857
CoMetGeNe: mining conserved neighborhood patterns in metabolic and genomic contexts. PMID:30630411
Epigallocatechin‑3‑gallate modulates long non‑coding RNA and mRNA expression profiles in lung cancer cells. PMID:30628683
Molecular evidence of field cancerization initiated by diabetes in colon cancer patients. PMID:30628165
MicroRNA Expression Profiles Identify Biomarker for Differentiating the Embolic Stroke from Thrombotic Stroke. PMID:30627556
Unique Transcriptional Architecture in Airway Epithelial Cells and Macrophages Shapes Distinct Responses following Influenza Virus Infection Ex Vivo. PMID:30626665
A novel signature derived from immunoregulatory and hypoxia genes predicts prognosis in liver and five other cancers. PMID:30626396
A measure of agreement across numerous conditions: assessing when changes in network structures are tissue-specific. PMID:30626339
Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample. PMID:30624610
Comparison of Bacillus subtilis transcriptome profiles from two separate missions to the International Space Station. PMID:30623021
Hypoxia Impairs Initial Outgrowth of Endothelial Colony Forming Cells and Reduces Their Proliferative and Sprouting Potential. PMID:30619865
Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [18F]-Flutemetamol PET Scan Result. PMID:30618716
MicroRNAs mediate liver transcriptome changes upon soy diet intervention in mice. PMID:30618122
RNA-seq analysis of hepatic gene expression of common Pekin, Muscovy, mule and hinny ducks fed ad libitum or overfed. PMID:30616512
Decoding the enigma of antiviral crisis: Does one target molecule regulate all? PMID:30616034
Microarray Data Analysis of Molecular Mechanism Associated with Stroke Progression. PMID:30610589
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A. PMID:30604225
Identification of potential miRNA-mRNA regulatory network contributing to pathogenesis of HBV-related HCC. PMID:30602391
Improvement of cancer subtype prediction by incorporating transcriptome expression data and heterogeneous biological networks. PMID:30598111
Identification of active signaling pathways by integrating gene expression and protein interaction data. PMID:30598083
Proteomic Analysis of Liver from Human Lipoprotein(a) Transgenic Mice Shows an Oxidative Stress and Lipid Export Response. PMID:30596094
Classification of Widely and Rarely Expressed Genes with Recurrent Neural Network. PMID:30595815
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. PMID:30595373
Effect of Age on the Protein Profile of Healthy Malay Adults and its Association with Cognitive Function Competency. PMID:30594926
Analysis of Dendrobium huoshanense transcriptome unveils putative genes associated with active ingredients synthesis. PMID:30594136
Possible epigenetic regulatory effect of dysregulated circular RNAs in epilepsy. PMID:30592747
Bioinformatic identification of key genes and pathways that may be involved in the pathogenesis of HBV-associated acute liver failure. PMID:30591937
Replisome Dynamics and Their Functional Relevance upon DNA Damage through the PCNA Interactome. PMID:30590055
OIP5 Promotes Growth, Metastasis and Chemoresistance to Cisplatin in Bladder Cancer Cells. PMID:30588253
17β-Estradiol protects the esophageal epithelium from IL-13-induced barrier dysfunction and remodeling. PMID:30578870
Cross-ID: Analysis and Visualization of Complex XL-MS-Driven Protein Interaction Networks. PMID:30575379
Drug-target-disease network analysis of gene-phenotype connectivity for genistein in ovarian cancer. PMID:30573976
High-resolution mapping of cancer cell networks using co-functional interactions. PMID:30573688
Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases. PMID:30573655
Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations. PMID:30572963
Cardiac function evaluation for a novel one-step detoxification product of Aconiti Lateralis Radix Praeparata. PMID:30568725
iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data. PMID:30567491
MafA Expression Preserves Immune Homeostasis in Human and Mouse Islets. PMID:30567413
Drug Repurposing for Japanese Encephalitis Virus Infection by Systems Biology Methods. PMID:30567313
Wound-Healing Markers Revealed by Proximity Extension Assay in Tears of Patients following Glaucoma Surgery. PMID:30567303
Transcriptomic profiles of muscle, heart, and spleen in reaction to circadian heat stress in Ethiopian highland and lowland male chicken. PMID:30565091
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization. PMID:30562941
Shotgun proteomics data on the impact of hyperglycaemia on platelet protein acetylation by aspirin. PMID:30560156
Gene co-expression networks from RNA sequencing of dairy cattle identifies genes and pathways affecting feed efficiency. PMID:30558534
Several genes involved in the JAK-STAT pathway may act as prognostic markers in pancreatic cancer identified by microarray data analysis. PMID:30557977
Transcriptome analyses identify key genes and potential mechanisms in a rat model of osteoarthritis. PMID:30551734
Identification of key genes and pathways by bioinformatics analysis with TCGA RNA sequencing data in hepatocellular carcinoma. PMID:30546887
Associating H2O2-and NO-related changes in the proteome of Mycobacterium smegmatis with enhanced survival in macrophage. PMID:30546046
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk. PMID:30545851
When pitch adds to volume: coregulation of transcript diversity predicts gene function. PMID:30545302
Network-based features enable prediction of essential genes across diverse organisms. PMID:30543651
Identifying the key genes and microRNAs in colorectal cancer liver metastasis by bioinformatics analysis and in vitro experiments. PMID:30542696
Integrative network-centric approach reveals signaling pathways associated with plant resistance and susceptibility to Pseudomonas syringae. PMID:30540739
Differential Gene Expression in Erlotinib-Treated Fibroblasts. PMID:30540703
Role of miRNAs in skeletal muscle aging. PMID:30538437
Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias. PMID:30538250
Regulatory motifs found in the small heat shock protein (sHSP) gene family in tomato. PMID:30537925
The MAGI2 gene polymorphism rs2160322 is associated with Graves' disease but not with Hashimoto's thyroiditis. PMID:30535759
Transcriptomic Landscape of von Economo Neurons in Human Anterior Cingulate Cortex Revealed by Microdissected-Cell RNA Sequencing. PMID:30535007
Proteome modifications on tomato under extreme high light induced-stress. PMID:30534005
Identification and Analysis of Rice Yield-Related Candidate Genes by Walking on the Functional Network. PMID:30524460
Identification of Five Genes as a Potential Biomarker for Predicting Progress and Prognosis in Adrenocortical Carcinoma. PMID:30519354
Identification of Grade-associated MicroRNAs in Brainstem Gliomas Based on Microarray Data. PMID:30519352
Comparative Transcriptomics of Rat and Axolotl After Spinal Cord Injury Dissects Differences and Similarities in Inflammatory and Matrix Remodeling Gene Expression Patterns. PMID:30519154
Multi-Study Proteomic and Bioinformatic Identification of Molecular Overlap between Amyotrophic Lateral Sclerosis (ALS) and Spinal Muscular Atrophy (SMA). PMID:30518112
Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function. PMID:30517875
An integrative machine learning approach for prediction of toxicity-related drug safety. PMID:30515477
Interactome determination of a Long Noncoding RNA implicated in Embryonic Stem Cell Self-Renewal. PMID:30514857
Characterization of paucibacillary ileal lesions in sheep with subclinical active infection by Mycobacterium avium subsp. paratuberculosis. PMID:30514405
Distinct prognostic value of dynactin subunit 4 (DCTN4) and diagnostic value of DCTN1, DCTN2, and DCTN4 in colon adenocarcinoma. PMID:30510450
The genome of the jellyfish Aurelia and the evolution of animal complexity. PMID:30510179
Identification of Key Potential Targets and Pathway for Arsenic Trioxide by Systemic Bioinformatics Analysis in Pancreatic Cancer. PMID:30506130
Data on differentially expressed proteins in retinal emmetropization process in guinea pig using integrated SWATH-based and targeted-based proteomics. PMID:30505911
Discrimination of contagious and environmental strains of Streptococcus uberis in dairy herds by means of mass spectrometry and machine-learning. PMID:30504894
Effects of Intrauterine Air Bubbles on Embryonic Development in Mice. PMID:30497539
Genomics of neonatal sepsis: has-miR-150 targeting BCL11B functions in disease progression. PMID:30497506
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses. PMID:30487575
Immunotherapy utilizing the combination of natural killer- and antibody dependent cellular cytotoxicity (ADCC)-mediating agents with poly (ADP-ribose) polymerase (PARP) inhibition. PMID:30486888
Microtubule-Based Control of Motor-Clutch System Mechanics in Glioma Cell Migration. PMID:30485822
RNA-seq profiling reveals differentially expressed genes as potential markers for vital reaction in skin contusion: a pilot study. PMID:30483664
Identification of gene expression profiles in myocardial infarction: a systematic review and meta-analysis. PMID:30482209
STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets. PMID:30476243
C1q and TNF related protein 1 regulates expression of inflammatory genes in vascular smooth muscle cells. PMID:30474828
Gene coexpression network analysis identified potential biomarkers in gestational diabetes mellitus progression. PMID:30474315
The Interaction of miR-378i-Skp2 Regulates Cell Senescence in Diabetic Nephropathy. PMID:30469549
Deciphering the transcriptome of prepubertal buffalo mammary glands using RNA sequencing. PMID:30467802
Pivotal role of bZIPs in amylose biosynthesis by genome survey and transcriptome analysis in wheat (Triticum aestivum L.) mutants. PMID:30467374
Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma. PMID:30464169
Quantitative Proteomics Reveals Antibiotics Resistance Function of Outer Membrane Proteins in Aeromonas hydrophila. PMID:30460208
Transcriptome sequencing combined with bioinformatics predicts potential genes and pathways associated with bupivacaine-induced apoptosis. PMID:30460060
Widespread roles of enhancer-like transposable elements in cell identity and long-range genomic interactions. PMID:30455182
Identification of core genes in ovarian cancer by an integrative meta-analysis. PMID:30453999
Gene Ontology-based function prediction of long non-coding RNAs using bi-random walk. PMID:30453964
Evaluating the impact of topological protein features on the negative examples selection. PMID:30453879
Expression analysis of RNA sequencing data from human neural and glial cell lines depends on technical replication and normalization methods. PMID:30453873
Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis. PMID:30451898
Next-generation sequencing identifies novel genes with rare variants in total anomalous pulmonary venous connection. PMID:30448225
Asymmetry in Mechanosensitive Gene Expression during Aortic Arch Morphogenesis. PMID:30446764
Listeriolysin O-dependent host surfaceome remodeling modulates Listeria monocytogenes invasion. PMID:30445439
Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors. PMID:30443181
Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation. PMID:30442662
Identification of key candidate genes and miRNA‑mRNA target pairs in chronic lymphocytic leukemia by integrated bioinformatics analysis. PMID:30431072
Determining the Balance Between Drug Efficacy and Safety by the Network and Biological System Profile of Its Therapeutic Target. PMID:30429792
Identification of hub genes with diagnostic values in pancreatic cancer by bioinformatics analyses and supervised learning methods. PMID:30428899
A Drug-Side Effect Context-Sensitive Network approach for drug target prediction. PMID:30428013
Identification of chemoresistance-associated miRNAs in breast cancer. PMID:30425571
Comprehensive bioinformatics analysis identifies several potential diagnostic markers and potential roles of cyclin family members in lung adenocarcinoma. PMID:30425528
De novo variant of TRRAP in a patient with very early onset psychosis in the context of non-verbal learning disability and obsessive-compulsive disorder: a case report. PMID:30424743
Ontology-based validation and identification of regulatory phenotypes. PMID:30423068
Gene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis. PMID:30420728
Identification of key genes and miRNAs markers of papillary thyroid cancer. PMID:30414611
Comparison of the effects of pachymic acid, moronic acid and hydrocortisone on the polysome loading of RNAs in lipopolysaccharide-treated THP-1 macrophages. PMID:30414015
Functional annotation of extensively and divergently expressed miRNAs in suprachiasmatic nucleus of Clock Δ19 mutant mice. PMID:30413606
A simple null model for inferences from network enrichment analysis. PMID:30412619
Identifying a Novel Biomarker TOP2A of Clear Cell Renal Cell Carcinoma (ccRCC) Associated with Smoking by Co-Expression Network Analysis. PMID:30410595
Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites. PMID:30409996
Identification of Core Biomarkers Associated with Outcome in Glioma: Evidence from Bioinformatics Analysis. PMID:30405856
Global Transcriptome Analysis During Adipogenic Differentiation and Involvement of Transthyretin Gene in Adipogenesis in Cattle. PMID:30405687
Toward the Language Oscillogenome. PMID:30405489
In silico Prediction, Characterization, Molecular Docking, and Dynamic Studies on Fungal SDRs as Novel Targets for Searching Potential Fungicides Against Fusarium Wilt in Tomato. PMID:30405403
ANCO-GeneDB: annotations and comprehensive analysis of candidate genes for alcohol, nicotine, cocaine and opioid dependence. PMID:30403795
Exploring Seipin: From Biochemistry to Bioinformatics Predictions. PMID:30402103
iTRAQ-Based Analysis of Proteins Co-Regulated by Brassinosteroids and Gibberellins in Rice Embryos during Seed Germination. PMID:30400353
The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex. PMID:30398641
Proteomic approach for understanding milder neurotoxicity of Carfilzomib against Bortezomib. PMID:30397214
Tangshen Formula Treatment for Diabetic Kidney Disease by Inhibiting Racgap1-stata5-Mediated Cell Proliferation and Restoring miR-669j-Arntl-Related Circadian Rhythm. PMID:30394366
Functional Voltage-Gated Calcium Channels Are Present in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium. PMID:30394009
Dysregulation of NCAPG, KNL1, miR-148a-3p, miR-193b-3p, and miR-1179 may contribute to the progression of gastric cancer. PMID:30390708
Limited short-term effects on human prostate cancer xenograft growth and epidermal growth factor receptor gene expression by the ghrelin receptor antagonist [D-Lys3]-GHRP-6. PMID:30390209
An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity. PMID:30389308
Construction of a Quantitative Acetylomic Tissue Atlas in Rice (Oryza sativa L.). PMID:30388832
A Network Biology Approach for Assessing the Role of Pathologic Adipose Tissues in Insulin Resistance Using Meta-analysis of Microarray Datasets. PMID:30386174
Bioinformatics-based analysis reveals elevated MFSD12 as a key promoter of cell proliferation and a potential therapeutic target in melanoma. PMID:30385854
Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis. PMID:30385787
Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis. PMID:30384176
Hunt for the tipping point during endocrine resistance process in breast cancer by dynamic network biomarkers. PMID:30383247
Classifying Incomplete Gene-Expression Data: Ensemble Learning with Non-Pre-Imputation Feature Filtering and Best-First Search Technique. PMID:30380746
DAZL Regulates Germ Cell Survival through a Network of PolyA-Proximal mRNA Interactions. PMID:30380414
HCN Regulates Cellular Processes through Posttranslational Modification of Proteins by S-cyanylation. PMID:30377236
Deep sequencing and miRNA profiles in alcohol-induced neuroinflammation and the TLR4 response in mice cerebral cortex. PMID:30374194
Transcriptome analyses of reprogrammed feather / scale chimeric explants revealed co-expressed epithelial gene networks during organ specification. PMID:30373532
Development and validation of the PEPPER framework (Prenatal Exposure PubMed ParsER) with applications to food additives. PMID:30371821
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances. PMID:30371672
Potential Therapeutic Drugs for Parkinson's Disease Based on Data Mining and Bioinformatics Analysis. PMID:30370044
Identification of Candidate Biomarkers Correlated With the Pathogenesis and Prognosis of Non-small Cell Lung Cancer via Integrated Bioinformatics Analysis. PMID:30369945
Identification of Potential Gene Interactions in Heart Failure Caused by Idiopathic Dilated Cardiomyopathy. PMID:30368515
A GPU-based algorithm for fast node label learning in large and unbalanced biomolecular networks. PMID:30367594
Identification of Potential miRNAs Biomarkers for High-Grade Prostate Cancer by Integrated Bioinformatics Analysis. PMID:30367364
Application of Proteomics Technologies in Oil Palm Research. PMID:30367348
IL-18 and S100A12 Are Upregulated in Experimental Central Retinal Vein Occlusion. PMID:30366444
Cytogenetic and Transcriptomic Analysis of Human Endometrial MSC Retaining Proliferative Activity after Sublethal Heat Shock. PMID:30366433
Co-Evolution of Intrinsically Disordered Proteins with Folded Partners Witnessed by Evolutionary Couplings. PMID:30366362
Identification of FOXM1 as a specific marker for triple‑negative breast cancer. PMID:30365046
Substrate Specificity Analysis of Dihydrofolate/Dihydromethanopterin Reductase Homologs in Methylotrophic α-Proteobacteria. PMID:30364315
Identification of candidate genes or microRNAs associated with the lymph node metastasis of SCLC. PMID:30364292
Genome-Wide Analysis of Genetic Variations and the Detection of Rich Variants of NBS-LRR Encoding Genes in Common Wild Rice Lines. PMID:30363818
Establishment of stably expandable induced myogenic stem cells by four transcription factors. PMID:30361642
Wood Smoke Exposure Alters Human Inflammatory Responses to Viral Infection in a Sex-Specific Manner. A Randomized, Placebo-controlled Study. PMID:30360637
iTRAQ-based quantitative analysis of age-specific variations in salivary proteome of caries-susceptible individuals. PMID:30359274
Gene expression variability across cells and species shapes innate immunity. PMID:30356220
Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation. PMID:30355343
Associations of Circulating Protein Levels With Lipid Fractions in the General Population. PMID:30354202
Integrated Succinylome and Metabolome Profiling Reveals Crucial Role of S-Ribosylhomocysteine Lyase in Quorum Sensing and Metabolism of Aeromonas hydrophila. PMID:30352804
Multi-tissue transcriptomes of caecilian amphibians highlight incomplete knowledge of vertebrate gene families. PMID:30351380
Genetic expression profile-based screening of genes and pathways associated with papillary thyroid carcinoma. PMID:30344727
Proteomic Analysis of Human Dermal Fibroblast Conditioned Medium (DFCM). PMID:30343346
Module-detection approaches for the integration of multilevel omics data highlight the comprehensive response of Aspergillus fumigatus to caspofungin. PMID:30342519
Transcriptome-wide effects of expansin gene manipulation in etiolated Arabidopsis seedling. PMID:30341720
Unveiling gibberellin-responsive coding and long noncoding RNAs in maize. PMID:30341662
Comparative Genomics of Lactobacillus brevis Reveals a Significant Plasmidome Overlap of Brewery and Insect Isolates. PMID:30341451
Mutational interactions define novel cancer subgroups. PMID:30341300
Prediction of Target Genes and Pathways Associated With Cetuximab Insensitivity in Colorectal Cancer. PMID:30336768
Transcriptome-wide association study identifies multiple genes and pathways associated with pancreatic cancer. PMID:30334361
Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors. PMID:30327455
Activation of a gene network in durum wheat roots exposed to cadmium. PMID:30326849
Analysis of impact metrics for the Protein Data Bank. PMID:30325351
Effects of rheumatoid arthritis associated transcriptional changes on osteoclast differentiation network in the synovium. PMID:30324023
Biomarkers for Early Stages of Johne's Disease Infection and Immunization in Goats. PMID:30323794
Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma. PMID:30322894
Prognostic value of DKK2 from the Dickkopf family in human breast cancer. PMID:30320375
A Calpain-Like Protein Is Involved in the Execution Phase of Programmed Cell Death of Entamoeba histolytica. PMID:30319995
CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming. PMID:30318302
Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics. PMID:30309851
Accurate prediction of protein-lncRNA interactions by diffusion and HeteSim features across heterogeneous network. PMID:30309340
Gene-based GWAS analysis for consecutive studies of GEFOS. PMID:30306226
In silico-prediction of protein-protein interactions network about MAPKs and PP2Cs reveals a novel docking site variants in Brachypodium distachyon. PMID:30305661
Genome-wide expression profiling of glioblastoma using a large combined cohort. PMID:30305647
Multimodal network diffusion predicts future disease-gene-chemical associations. PMID:30304494
N-dodecanoyl-homoserine lactone influences the levels of thiol and proteins related to oxidation-reduction process in Salmonella. PMID:30304064
Differentially expressed protein and gene analysis revealed the effects of temperature on changes in ascorbic acid metabolism in harvested tea leaves. PMID:30302261
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs. PMID:30299501
Typing tumors using pathways selected by somatic evolution. PMID:30297789
Smoking-induced control of miR-133a-3p alters the expression of EGFR and HuR in HPV-infected oropharyngeal cancer. PMID:30289952
Identification of Key Genes and Pathways Associated with RUNX1 Mutations in Acute Myeloid Leukemia Using Bioinformatics Analysis. PMID:30289875
Systematic expression alteration analysis of master reprogramming factor OCT4 and its three pseudogenes in human cancer and their prognostic outcomes. PMID:30287838
High-throughput proteomic profiling of the fish liver following bacterial infection. PMID:30285610
Proteomic Investigation of Murine Neuronal α7-Nicotinic Acetylcholine Receptor Interacting Proteins. PMID:30285449
Quantitative proteomics analysis of sporadic parathyroid adenoma tissue samples. PMID:30284223
Parallel evolution of gene expression between trophic specialists despite divergent genotypes and morphologies. PMID:30283665
Characterization and Expression Patterns of Auxin Response Factors in Wheat. PMID:30283490
The role of miR-106p-5p in cervical cancer: from expression to molecular mechanism. PMID:30275981
Pathogenic and non-pathogenic Escherichia coli colonization and host inflammatory response in a defined microbiota mouse model. PMID:30275104
Gene Regulatory Network Analysis Identifies Sex-Linked Differences in Colon Cancer Drug Metabolism. PMID:30275053
Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice. PMID:30273559
Identification of COL1A1 as an invasion‑related gene in malignant astrocytoma. PMID:30272346
Gene module analysis of juvenile myelomonocytic leukemia and screening of anticancer drugs. PMID:30272300
Multiplexed deactivated CRISPR-Cas9 gene expression perturbations deter bacterial adaptation by inducing negative epistasis. PMID:30272008
Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease. PMID:30271679
The Diurnal Timing of Starvation Differently Impacts Murine Hepatic Gene Expression and Lipid Metabolism - A Systems Biology Analysis Using Self-Organizing Maps. PMID:30271348
Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase. PMID:30266825
WEADE: A workflow for enrichment analysis and data exploration. PMID:30265728
Structure and Protein Interaction-Based Gene Ontology Annotations Reveal Likely Functions of Uncharacterized Proteins on Human Chromosome 17. PMID:30265558
Darkness in the Human Gene and Protein Function Space: Widely Modest or Absent Illumination by the Life Science Literature and the Trend for Fewer Protein Function Discoveries Since 2000. PMID:30265449
Combined linkage and association analysis identifies rare and low frequency variants for blood pressure at 1q31. PMID:30262922
Ovarian Tumor Microenvironment Signaling: Convergence on the Rac1 GTPase. PMID:30261690
Fold change based approach for identification of significant network markers in breast, lung and prostate cancer. PMID:30259866
Meta-analysis of data from spaceflight transcriptome experiments does not support the idea of a common bacterial "spaceflight response". PMID:30258082
Rare genetic variation in mitochondrial pathways influences the risk for Parkinson's disease. PMID:30256453
Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity. PMID:30256117
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING. PMID:30254094
Genome-wide analyses of genes encoding FK506-binding proteins reveal their involvement in abiotic stress responses in apple. PMID:30253753
Obesity modifies the stoichiometry of mitochondrial proteins in a way that is distinct to the subcellular localization of the mitochondria in skeletal muscle. PMID:30253140
Identification of a 3'-Untranslated Genetic Variant of RARB Associated With Carotid Intima-Media Thickness in Rheumatoid Arthritis: A Genome-Wide Association Study. PMID:30251476
MaxMIF: A New Method for Identifying Cancer Driver Genes through Effective Data Integration. PMID:30250803
Identification of potential biomarkers in cervical cancer with combined public mRNA and miRNA expression microarray data analysis. PMID:30250588
A meta-analysis and bioinformatics exploration of the diagnostic value and molecular mechanism of miR-193a-5p in lung cancer. PMID:30250529
Potential use of compounds from sea cucumbers as MDM2 and CXCR4 inhibitors to control cancer cell growth. PMID:30250516
Individual variations in cardiovascular-disease-related protein levels are driven by genetics and gut microbiome. PMID:30250126
Molecular pathology of adverse local tissue reaction caused by metal-on-metal implants defined by RNA-seq. PMID:30248488
A four-gene-based prognostic model predicts overall survival in patients with hepatocellular carcinoma. PMID:30247807
C5aR1 interacts with TLR2 in osteoblasts and stimulates the osteoclast-inducing chemokine CXCL10. PMID:30247799
Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice. PMID:30241514
Role of altered proteostasis network in chronic hypobaric hypoxia induced skeletal muscle atrophy. PMID:30240405
Global Profiling of Lysine Acetylation in Borrelia burgdorferi B31 Reveals Its Role in Central Metabolism. PMID:30233522
Genome-Wide Identification and Analysis of Apple NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER Family (NPF) Genes Reveals MdNPF6.5 Confers High Capacity for Nitrogen Uptake under Low-Nitrogen Conditions. PMID:30223432
Functional Proteomics and Deep Network Interrogation Reveal a Complex Mechanism of Action of Midostaurin in Lung Cancer Cells. PMID:30217950
Identification and Analysis of Blood Gene Expression Signature for Osteoarthritis With Advanced Feature Selection Methods. PMID:30214455
High-Reynolds Microfluidic Sorting of Large Yeast Populations. PMID:30214051
Screening of genes associated with inflammatory responses in the endolymphatic sac reveals underlying mechanisms for autoimmune inner ear diseases. PMID:30210597
Genome Sequencing Reveals a Large and Diverse Repertoire of Antimicrobial Peptides. PMID:30210481
Cyclocarya paliurus Leaves Tea Improves Dyslipidemia in Diabetic Mice: A Lipidomics-Based Network Pharmacology Study. PMID:30210345
Differential HDAC1/2 network analysis reveals a role for prefoldin/CCT in HDAC1/2 complex assembly. PMID:30209338
Genomic, expressional, protein-protein interactional analysis of Trihelix transcription factor genes in Setaria italia and inference of their evolutionary trajectory. PMID:30208846
SOX2OT knockdown derived changes in mitotic regulatory gene network of cancer cells. PMID:30202240
Proteomic Approaches for the Discovery of Biofluid Biomarkers of Neurodegenerative Dementias. PMID:30200280
Approaches to the discovery of non-invasive urinary biomarkers of prostate cancer. PMID:30197761
Integrative Analysis of lncRNAs in Th17 Cell Lineage to Discover New Potential Biomarkers and Therapeutic Targets in Autoimmune Diseases. PMID:30195777
Machine Learning Predicts the Yeast Metabolome from the Quantitative Proteome of Kinase Knockouts. PMID:30195436
Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response. PMID:30193848
Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples. PMID:30190427
Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways. PMID:30190326
Characterization of Spleen Transcriptome and Immunity Against Avian Colibacillosis After Immunization With Recombinant Attenuated Salmonella Vaccine Strains. PMID:30186843
Comparison of structures among Saccharomyces cerevisiae Grxs proteins. PMID:30186535
Bioinformatics identification of potential candidate blood indicators for doxorubicin-induced heart failure. PMID:30186487
Generation of iPSC-Derived Human Peripheral Sensory Neurons Releasing Substance P Elicited by TRPV1 Agonists. PMID:30186108
Genome wide association study identifies novel potential candidate genes for bovine milk cholesterol content. PMID:30185830
A kernel machine method for detecting higher order interactions in multimodal datasets: Application to schizophrenia. PMID:30184473
Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations. PMID:30181117
Molecular mechanism of activated T cells in breast cancer. PMID:30174439
Proteome Profiling of Primary Pancreatic Ductal Adenocarcinomas Undergoing Additive Chemoradiation Link ALDH1A1 to Early Local Recurrence and Chemoradiation Resistance. PMID:30172883
ANNOgesic: a Swiss army knife for the RNA-seq based annotation of bacterial/archaeal genomes. PMID:30169674
Hotspot mutations and ColE1 plasmids contribute to the fitness of Salmonella Heidelberg in poultry litter. PMID:30169497
Identification and Interaction Analysis of Molecular Markers in Colorectal Cancer by Integrated Bioinformatics Analysis. PMID:30168505
Efficient QTL detection of flowering date in a soybean RIL population using the novel restricted two-stage multi-locus GWAS procedure. PMID:30167759
iTRAQ-based analysis of sperm proteome from normozoospermic men achieving the rescue-ICSI pregnancy after the IVF failure. PMID:30166971
Co-expression Network Analysis of Biomarkers for Adrenocortical Carcinoma. PMID:30158955
Clustering approaches for visual knowledge exploration in molecular interaction networks. PMID:30157777
miR-124-3p is a chronic regulator of gene expression after brain injury. PMID:30155647
Differential Gene Expression Caused by the F and M Loci Provides Insight Into Ethylene-Mediated Female Flower Differentiation in Cucumber. PMID:30154805
Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes. PMID:30154505
Outer membrane lipoprotein RlpA is a novel periplasmic interaction partner of the cell division protein FtsK in Escherichia coli. PMID:30154462
An interaction network driven approach for identifying biomarkers for progressing cervical intraepithelial neoplasia. PMID:30150654
Identification of key genes and pathways using bioinformatics analysis in septic shock children. PMID:30147344
Potential role of LINC00996 in colorectal cancer: a study based on data mining and bioinformatics. PMID:30147336
Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation. PMID:30143610
Differential Induction of IFN-α and Modulation of CD112 and CD54 Expression Govern the Magnitude of NK Cell IFN-γ Response to Influenza A Viruses. PMID:30143589
Exploring prognostic genes in ovarian cancer stage-related coexpression network modules. PMID:30142790
Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma. PMID:30138346
Prediction of key genes and pathways involved in trastuzumab-resistant gastric cancer. PMID:30134903
An impaired hepatic clock system effects lipid metabolism in rats with nephropathy. PMID:30132511
Developmental effects of maternal smoking during pregnancy on the human frontal cortex transcriptome. PMID:30131587
Potential biomarkers of HCC based on gene expression and DNA methylation profiles. PMID:30127913
Screening and identification of key biomarkers in bladder carcinoma: Evidence from bioinformatics analysis. PMID:30127900
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry. PMID:30127528
PPInS: a repository of protein-protein interaction sitesbase. PMID:30127348
Proteome-wide analysis of phospho-regulated PDZ domain interactions. PMID:30126976
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells. PMID:30125269
Bioinformatics analysis of microarray data to reveal the pathogenesis of diffuse intrinsic pontine glioma. PMID:30124166
Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers. PMID:30123424
Systematic Analysis of Differential Expression Profile in Rheumatoid Arthritis Chondrocytes Using Next-Generation Sequencing and Bioinformatics Approaches. PMID:30123050
Bioinformatic analysis of four miRNAs relevant to metastasis-regulated processes in endometrial carcinoma. PMID:30122983
QTL Alignment for Seed Yield and Yield Related Traits in Brassica napus. PMID:30116254
A unified resource for transcriptional regulation in Escherichia coli K-12 incorporating high-throughput-generated binding data into RegulonDB version 10.0. PMID:30115066
A New Strategy to Uncover the Anticancer Mechanism of Chinese Compound Formula by Integrating Systems Pharmacology and Bioinformatics. PMID:30108661
A Swath Label-Free Proteomics insight into the Faah-/- Mouse Liver. PMID:30108271
Kv1.3 channel blockade with the Vm24 scorpion toxin attenuates the CD4+ effector memory T cell response to TCR stimulation. PMID:30107837
Transcriptome sequencing identifies key pathways and genes involved in gastric adenocarcinoma. PMID:30106143
Tetraspanin family identified as the central genes detected in gastric cancer using bioinformatics analysis. PMID:30106120
Intercepting signalling mechanism to control environmental biofouling. PMID:30105189
Sonic Hedgehog Medulloblastoma Cancer Stem Cells Mirnome and Transcriptome Highlight Novel Functional Networks. PMID:30096798
Bioinformatics-based analysis of the involvement of AC005550.3, RP11-415D17.3, and RP1-140K8.5 in homocysteine-induced vascular endothelial injury. PMID:30093949
Circulating ectosomes: Determination of angiogenic microRNAs in type 2 diabetes. PMID:30083267
Proteomic Analysis of Ubiquitinated Proteins in Rice (Oryza sativa) After Treatment With Pathogen-Associated Molecular Pattern (PAMP) Elicitors. PMID:30083178
Temporal Proteomic Analysis of Pancreatic β-Cells in Response to Lipotoxicity and Glucolipotoxicity. PMID:30082485
A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle. PMID:30081931
Contribution of Inhibitor of Differentiation and Estrogenic Endocrine Disruptors to Neurocognitive Disorders. PMID:30081481
Genome-wide analysis of DNA polymorphisms, the methylome and transcriptome revealed that multiple factors are associated with low pollen fertility in autotetraploid rice. PMID:30080873
Structural, functional and evolutionary diversity of 4-coumarate-CoA ligase in plants. PMID:30078075
Inferring Novel Tumor Suppressor Genes with a Protein-Protein Interaction Network and Network Diffusion Algorithms. PMID:30069494
Overexpression of the Kininogen-1 inhibits proliferation and induces apoptosis of glioma cells. PMID:30068373
PATRI, a Genomics Data Integration Tool for Biomarker Discovery. PMID:30065933
Pan-Cancer Analysis Reveals the Functional Importance of Protein Lysine Modification in Cancer Development. PMID:30065750
An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria. PMID:30065086
Comparative iTRAQ proteomics revealed proteins associated with horn development in yak. PMID:30061793
Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart. PMID:30061404
Pathway enrichment and protein interaction network analysis for milk yield, fat yield and age at first calving in a Thai multibreed dairy population. PMID:30056656
Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer. PMID:30055645
Whole-exome sequencing identifies rare genetic variations in German families with pulmonary sarcoidosis. PMID:30054724
The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders. PMID:30053424
Structural Analysis of Hippocampal Kinase Signal Transduction. PMID:30053369
Dose- and time-dependent effects of triethylene glycol dimethacrylate on the proteome of human THP-1 monocytes. PMID:30051916
Cross-Species Meta-Analysis of Transcriptomic Data in Combination With Supervised Machine Learning Models Identifies the Common Gene Signature of Lactation Process. PMID:30050559
Effect of Productive Human Papillomavirus 16 Infection on Global Gene Expression in Cervical Epithelium. PMID:30045992
Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma. PMID:30045945
A centriolar FGR1 oncogene partner-like protein required for paraflagellar rod assembly, but not axoneme assembly in African trypanosomes. PMID:30045883
Meta-analysis of transcriptomic responses to biotic and abiotic stress in tomato. PMID:30038850
Mapping the genetic basis of breast microcalcifications and their role in metastasis. PMID:30038419
A SIRT1-centered circuitry regulates breast cancer stemness and metastasis. PMID:30038266
RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer. PMID:30037330
Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB. PMID:30024968
High-glucose-induced changes in macrophage secretome: regulation of immune response. PMID:30022449
A multiomics analysis of S100 protein family in breast cancer. PMID:30018736
An unsupervised machine learning method for discovering patient clusters based on genetic signatures. PMID:30016722
Comprehensive analysis of gene expression profiles provides insight into the pathogenesis of Crohn's disease. PMID:30015893
Candidate gene and mechanism investigations in congenital obstructive nephropathy based on bioinformatics analysis. PMID:30015886
Chemogenomics Systems Pharmacology Mapping of Potential Drug Targets for Treatment of Traumatic Brain Injury. PMID:30014763
Identification of potential target genes in pancreatic ductal adenocarcinoma by bioinformatics analysis. PMID:30013637
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis. PMID:30013184
Quantitative temporal analysis of protein dynamics in cardiac remodeling. PMID:30009778
Cross talk of chromosome instability, CpG island methylator phenotype and mismatch repair in colorectal cancer. PMID:30008861
Endophytic Bacillus and Pseudomonas spp. Modulate Apple Shoot Growth, Cellular Redox Balance, and Protein Expression Under in Vitro Conditions. PMID:30002666
CDG: An Online Server for Detecting Biologically Closest Disease-Causing Genes and its Application to Primary Immunodeficiency. PMID:29997612
Identification and functional annotation of metabolism-associated lncRNAs and their related protein-coding genes in gastric cancer. PMID:29992774
Analysis of protein-protein interaction network based on transcriptome profiling of ovine granulosa cells identifies candidate genes in cyclic recruitment of ovarian follicles. PMID:29992036
Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function. PMID:29988084
Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response. PMID:29986055
A common molecular signature of patients with sickle cell disease revealed by microarray meta-analysis and a genome-wide association study. PMID:29979707
Unveiling "Musica Universalis" of the Cell: A Brief History of Biological 12-Hour Rhythms. PMID:29978151
A novel PKP2 mutation and intrafamilial phenotypic variability in ARVC/D. PMID:29977873
Bioinformatics analysis of microarray data to explore the key genes involved in HSF4 mutation-induced cataract. PMID:29977800
The Identification of Core Gene Expression Signature in Hepatocellular Carcinoma. PMID:29977454
Time resolved quantitative phospho-tyrosine analysis reveals Bruton's Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors. PMID:29977015
Comparative Secretome Profiling and Mutant Protein Identification in Metastatic Prostate Cancer Cells by Quantitative Mass Spectrometry-based Proteomics. PMID:29976633
Identification of Antifungal Targets Based on Computer Modeling. PMID:29973534
Proteomic Profiling of Microtubule Self-organization in M-phase. PMID:29970457
Protein Carbonylation and Glycation in Legume Nodules. PMID:29970413
Integrated Analysis and Identification of Novel Biomarkers in Parkinson's Disease. PMID:29967579
Cluster-assembled zirconia substrates promote long-term differentiation and functioning of human islets of Langerhans. PMID:29967323
Harnessing synthetic lethality to predict the response to cancer treatment. PMID:29959327
Proteomic Analysis of Hippocampus in a Mouse Model of Depression Reveals Neuroprotective Function of Ubiquitin C-terminal Hydrolase L1 (UCH-L1) via Stress-induced Cysteine Oxidative Modifications. PMID:29959188
Quorum sensing in thermophiles: prevalence of autoinducer-2 system. PMID:29954335
Transferring knowledge of bacterial protein interaction networks to predict pathogen targeted human genes and immune signaling pathways: a case study on M. tuberculosis. PMID:29954330
Novel insights into global translational regulation through Pumilio family RNA-binding protein Puf3p revealed by ribosomal profiling. PMID:29951697
A Possible Mechanism: Vildagliptin Prevents Aortic Dysfunction through Paraoxonase and Angiopoietin-Like 3. PMID:29951533
Generation and In Vivo Characterization of Tn5-Induced Biofilm Mutants of Vibrio cholerae O139. PMID:29948009
In silico approach in reveal traditional medicine plants pharmacological material basis. PMID:29946351
The Ferredoxin-Like Proteins HydN and YsaA Enhance Redox Dye-Linked Activity of the Formate Dehydrogenase H Component of the Formate Hydrogenlyase Complex. PMID:29942290
Experimental evidence for rapid genomic adaptation to a new niche in an adaptive radiation. PMID:29942074
The arrhythmogenic cardiomyopathy-specific coding and non-coding transcriptome in human cardiac stromal cells. PMID:29940860
Leader gene of Corynebacterium pseudotuberculosis may be useful in vaccines against caseous lymphadenitis of goats: a bioinformatics approach. PMID:29937460
Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. PMID:29937354
Progression Rate Associated Peripheral Blood Biomarkers of Parkinson's Disease. PMID:29936662
Exploring the functional impact of alternative splicing on human protein isoforms using available annotation sources. PMID:29931155
Adipocytes induce distinct gene expression profiles in mammary tumor cells and enhance inflammatory signaling in invasive breast cancer cells. PMID:29930291
A cytokine protein-protein interaction network for identifying key molecules in rheumatoid arthritis. PMID:29928007
Computational Methods for Predicting Protein-Protein Interactions Using Various Protein Features. PMID:29927082
Molecular Characterization and Putative Pathogenic Pathways of Tuberous Sclerosis Complex-Associated Renal Cell Carcinoma. PMID:29925043
Identification of hepatic protein-protein interaction targets for betaine homocysteine S-methyltransferase. PMID:29924862
Narrowing the Genetic Causes of Language Dysfunction in the 1q21.1 Microduplication Syndrome. PMID:29922639
Differential Proteomic Analysis of Lactic Acid Bacteria-Escherichia coli O157:H7 Interaction and Its Contribution to Bioprotection Strategies in Meat. PMID:29922248
Cerebrospinal Fluid Concentrations of Neuronal Proteins Are Reduced in Primary Angiitis of the Central Nervous System. PMID:29922220
DeCoST: A New Approach in Drug Repurposing From Control System Theory. PMID:29922160
Developments in toxicogenomics: understanding and predicting compound-induced toxicity from gene expression data. PMID:29917034
Structural insights and characterization of human Npas4 protein. PMID:29915698
Molecular signature of progenitor cells isolated from young and adult human hearts. PMID:29915261
GeNets: a unified web platform for network-based genomic analyses. PMID:29915188
Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data. PMID:29914350
Unravelling the pathogenic role and genotype-phenotype correlation of the USH2A p.(Cys759Phe) variant among Spanish families. PMID:29912909
Genes Whose Gain or Loss-Of-Function Increases Skeletal Muscle Mass in Mice: A Systematic Literature Review. PMID:29910734
NRDE-2, the human homolog of fission yeast Nrl1, prevents DNA damage accumulation in human cells. PMID:29902117
Screening genes associated with elevated neutrophil‑to‑lymphocyte ratio in chronic heart failure. PMID:29901123
Identification of genes and signaling pathways associated with the pathogenesis of juvenile spondyloarthritis. PMID:29901120
Proteomic analysis reveals differential protein expression in variants of papillary thyroid carcinoma. PMID:29900122
Quantitative proteomic analysis identifies proteins and pathways related to neuronal development in differentiated SH-SY5Y neuroblastoma cells. PMID:29900121
Top-down proteomic characterization of DAOY medulloblastoma tumor cell line. PMID:29900115
Modulation of Cellular CpG DNA Methylation by Kaposi's Sarcoma-Associated Herpesvirus. PMID:29899086
Identification of drug-target interaction by a random walk with restart method on an interactome network. PMID:29897326
Missense variants in ATP1A3 and FXYD gene family are associated with childhood-onset schizophrenia. PMID:29895895
A transcriptomic survey of the impact of environmental stress on response to dengue virus in the mosquito, Aedes aegypti. PMID:29889847
Differentially Expressed Genes in Osteomyelitis Induced by Staphylococcus aureus Infection. PMID:29887852
Integrated analysis of long noncoding RNA and mRNA expression profile in children with obesity by microarray analysis. PMID:29884798
Identification of key genes in human airway epithelial cells in response to respiratory pathogens using microarray analysis. PMID:29884128
Family specific genetic predisposition to breast cancer: results from Tunisian whole exome sequenced breast cancer cases. PMID:29879995
Candidate gene biodosimetry markers of exposure to external ionizing radiation in human blood: A systematic review. PMID:29879226
Genomic atlas of the human plasma proteome. PMID:29875488
Network-based machine learning and graph theory algorithms for precision oncology. PMID:29872707
Chromosomal breaks at FRA18C: association with reduced DOK6 expression, altered oncogenic signaling and increased gastric cancer survival. PMID:29872697
Agrin has a pathological role in the progression of oral cancer. PMID:29872149
Discovering mutated driver genes through a robust and sparse co-regularized matrix factorization framework with prior information from mRNA expression patterns and interaction network. PMID:29871594
Temporal profiling of redox-dependent heterogeneity in single cells. PMID:29869985
Reverse Screening Methods to Search for the Protein Targets of Chemopreventive Compounds. PMID:29868550
Meta-Analysis of Maternal and Fetal Transcriptomic Data Elucidates the Role of Adaptive and Innate Immunity in Preterm Birth. PMID:29867970
Changed Expression of Cytoskeleton Proteins During Lung Injury in a Mouse Model of Streptococcus pneumoniae Infection. PMID:29867838
Transcriptome Changes of Escherichia coli, Enterococcus faecalis, and Escherichia coli O157:H7 Laboratory Strains in Response to Photo-Degraded DOM. PMID:29867797
Tensor Decomposition-Based Unsupervised Feature Extraction Can Identify the Universal Nature of Sequence-Nonspecific Off-Target Regulation of mRNA Mediated by MicroRNA Transfection. PMID:29867052
Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer. PMID:29861157
Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci. PMID:29860282
Deconstructive somatic cell nuclear transfer reveals novel regulatory T-cell subsets. PMID:29857010
Intrauterine hyperglycemia induces intergenerational Dlk1-Gtl2 methylation changes in mouse placenta. PMID:29854287
New insights into donor directionality of mating-type switching in Schizosaccharomyces pombe. PMID:29852001
Identification of key genes in rheumatoid arthritis and osteoarthritis based on bioinformatics analysis. PMID:29851858
Computational Approach to Investigating Key GO Terms and KEGG Pathways Associated with CNV. PMID:29850576
Identification of Key Genes and miRNAs in Osteosarcoma Patients with Chemoresistance by Bioinformatics Analysis. PMID:29850522
Computational approaches for predicting key transcription factors in targeted cell reprogramming (Review). PMID:29845286
Identification of key gene networks associated with fracture healing using αSMA‑labeled progenitor cells. PMID:29845231
Genes associated with inflammation and the cell cycle may serve as biomarkers for the diagnosis and prognosis of acute myocardial infarction in a Chinese population. PMID:29845217
E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments. PMID:29844366
A computational framework for complex disease stratification from multiple large-scale datasets. PMID:29843806
Vaccine antigens modulate the innate response of monocytes to Al(OH)3. PMID:29813132
Distinct Prognostic Values of Alcohol Dehydrogenase Family Members for Non-Small Cell Lung Cancer. PMID:29808834
Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication. PMID:29807781
Regulatory interactions between long noncoding RNA LINC00968 and miR-9-3p in non-small cell lung cancer: A bioinformatic analysis based on miRNA microarray, GEO and TCGA. PMID:29805671
Identification and bioinformatics analysis of overlapping differentially expressed genes in depression, papillary thyroid cancer and uterine fibroids. PMID:29805500
In vivo response of xanthosine on mammary gene expression of lactating Beetal goat. PMID:29804277
Demographic History and Genetic Adaptation in the Himalayan Region Inferred from Genome-Wide SNP Genotypes of 49 Populations. PMID:29796643
FAM188B enhances cell survival via interaction with USP7. PMID:29795372
Cell division cycle 7 kinase is a negative regulator of cell-mediated collagen degradation. PMID:29792348
Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation. PMID:29789417
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. PMID:29789389
Identification of potential crucial genes and pathways associated with vein graft restenosis based on gene expression analysis in experimental rabbits. PMID:29785339
A Computational Approach Using Bioinformatics to Screening Drug Targets for Leishmania infantum Species. PMID:29785196
miR-199b-5p Regulates Immune-Mediated Allograft Rejection after Lung Transplantation Through the GSK3β and NF-κB Pathways. PMID:29779167
Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas. PMID:29778837
Molecular characterization of physis tissue by RNA sequencing. PMID:29775757
p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis. PMID:29775581
Proteomic profiling of skeletal and cardiac muscle in cancer cachexia: alterations in sarcomeric and mitochondrial protein expression. PMID:29774118
Comparative Proteomic and Morphological Change Analyses of Staphylococcus aureus During Resuscitation From Prolonged Freezing. PMID:29774015
Abnormally high expression of POLD1, MCM2, and PLK4 promotes relapse of acute lymphoblastic leukemia. PMID:29768346
LitVar: a semantic search engine for linking genomic variant data in PubMed and PMC. PMID:29762787
MRMAssayDB: an integrated resource for validated targeted proteomics assays. PMID:29762640
Molecular functional analyses revealed essential roles of HSP90 and lamin A/C in growth, migration, and self-aggregation of dermal papilla cells. PMID:29760951
Identification of potential crucial genes and construction of microRNA-mRNA negative regulatory networks in osteosarcoma. PMID:29760609
Genome-wide association pathway analysis to identify candidate single nucleotide polymorphisms and molecular pathways associated with TP53 expression status in HBV-related hepatocellular carcinoma. PMID:29760565
Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer. PMID:29760449
Combined Transcriptomics, Proteomics and Bioinformatics Identify Drug Targets in Spinal Cord Injury. PMID:29758010
Serum-derived carcinoembryonic antigen (CEA) activates fibroblasts to induce a local re-modeling of the extracellular matrix that favors the engraftment of CEA-expressing tumor cells. PMID:29756328
Decoding Common Features of Neurodegenerative Disorders: From Differentially Expressed Genes to Pathways. PMID:29755292
Preconception Carrier Screening by Genome Sequencing: Results from the Clinical Laboratory. PMID:29754767
Cellular stress responses to chronic heat shock and shell damage in temperate Mya truncata. PMID:29754331
Single-cell RNA-seq of human induced pluripotent stem cells reveals cellular heterogeneity and cell state transitions between subpopulations. PMID:29752298
Comprehensive analysis of the clinical significance and prospective molecular mechanisms of differentially expressed autophagy-related genes in thyroid cancer. PMID:29749543
Bioinformatics analysis of microarray data to reveal the pathogenesis of brain ischemia. PMID:29749511
Identification of genes and pathways associated with multiple organ dysfunction syndrome by microarray analysis. PMID:29749505
SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS. PMID:29748379
Translational control plays an important role in the adaptive heat-shock response of Streptomyces coelicolor. PMID:29746664
INTERSPIA: a web application for exploring the dynamics of protein-protein interactions among multiple species. PMID:29746660
Profiling the Serum Protein Corona of Fibrillar Human Islet Amyloid Polypeptide. PMID:29746093
Identification of novel drug targets for diamond-blackfan anemia based on RPS19 gene mutation using protein-protein interaction network. PMID:29745857
Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy. PMID:29744371
A MIXED-EFFECTS MODEL FOR INCOMPLETE DATA FROM LABELING-BASED QUANTITATIVE PROTEOMICS EXPERIMENTS. PMID:29743963
CXCL12/CXCR4 Signaling Enhances Human PSC-Derived Hematopoietic Progenitor Function and Overcomes Early In Vivo Transplantation Failure. PMID:29742393
SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program. PMID:29741478
Identification of potential diagnostic and prognostic biomarkers in non-small cell lung cancer based on microarray data. PMID:29731852
Identification of aberrantly expressed F-box proteins in squamous-cell lung carcinoma. PMID:29728763
PregOMICS-Leveraging systems biology and bioinformatics for drug repurposing in maternal-child health. PMID:29726581
Inhibition of miR-486 and miR-92a decreases liver and plasma cholesterol levels by modulating lipid-related genes in hyperlipidemic hamsters. PMID:29725814
Analysis of the microRNA signature in left atrium from patients with valvular heart disease reveals their implications in atrial fibrillation. PMID:29723239
Core signaling pathways in ovarian cancer stem cell revealed by integrative analysis of multi-marker genomics data. PMID:29723215
Genetic susceptibility to bone and soft tissue sarcomas: a field synopsis and meta-analysis. PMID:29719630
LYL1 gene amplification predicts poor survival of patients with uterine corpus endometrial carcinoma: analysis of the Cancer genome atlas data. PMID:29716549
Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer. PMID:29715290
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network. PMID:29712938
Systematic analysis of copy number variation associated with congenital diaphragmatic hernia. PMID:29712845
Pulmonary Surfactant Promotes Virulence Gene Expression and Biofilm Formation in Klebsiella pneumoniae. PMID:29712730
Structural and functional dissection of differentially expressed tomato WRKY transcripts in host defense response against the vascular wilt pathogen (Fusarium oxysporum f. sp. lycopersici). PMID:29709017
Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms. PMID:29706353
A network map of IL-33 signaling pathway. PMID:29705949
NF-Y-dependent regulation of glutamate receptor 4 expression and cell survival in cells of the oligodendrocyte lineage. PMID:29704264
A side-effect free method for identifying cancer drug targets. PMID:29703908
Simultaneous sequencing of coding and noncoding RNA reveals a human transcriptome dominated by a small number of highly expressed noncoding genes. PMID:29703781
The Emerging Immunogenetic Architecture of Schizophrenia. PMID:29701842
Proteomic Analysis of Cerebral Cortex Extracts from Sus scrofa with Induced Hemorrhagic Stroke. PMID:29700768
New perspectives: systems medicine in cardiovascular disease. PMID:29699591
Serum Proteomics in African American Female Patients With Irritable Bowel Syndrome: An Exploratory Study. PMID:29698332
Genetic interaction between two insulin-dependent diabetes susceptibility loci, Idd2 and Idd13, in determining immunoregulatory DN T cell proportion. PMID:29696366
Exploring the Pharmacological Mechanism of Danzhi Xiaoyao Powder on ER-Positive Breast Cancer by a Network Pharmacology Approach. PMID:29692855
dbDEPC 3.0: the database of differentially expressed proteins in human cancer with multi-level annotation and drug indication. PMID:29688359
Microarray Analysis of the Molecular Mechanism Involved in Parkinson's Disease. PMID:29686831
Association of CACNA1C with bipolar disorder among the Pakistani population. PMID:29684488
Navigating the disease landscape: knowledge representations for contextualizing molecular signatures. PMID:29684165
One for all and all for One: Improving replication of genetic studies through network diffusion. PMID:29684019
Micromanaging freeze tolerance: the biogenesis and regulation of neuroprotective microRNAs in frozen brains. PMID:29681008
IFN-λ and microRNAs are important modulators of the pulmonary innate immune response against influenza A (H1N2) infection in pigs. PMID:29677213
Mining TCGA database for genes of prognostic value in glioblastoma microenvironment. PMID:29676997
Bioinformatic Integration of Molecular Networks and Major Pathways Involved in Mice Cochlear and Vestibular Supporting Cells. PMID:29674954
Comparative transcriptome analysis to investigate the potential role of miRNAs in milk protein/fat quality. PMID:29674689
Shape-Shifted Red Blood Cells: A Novel Red Blood Cell Stage? PMID:29671811
Possible Molecular Markers for the Diagnosis of Pancreatic Ductal Adenocarcinoma. PMID:29671412
Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor. PMID:29670360
Global H3.3 dynamic deposition defines its bimodal role in cell fate transition. PMID:29670118
Recurrent Patterns of Protein Expression Signatures in Pediatric Acute Lymphoblastic Leukemia: Recognition and Therapeutic Guidance. PMID:29669823
Recognition of Recurrent Protein Expression Patterns in Pediatric Acute Myeloid Leukemia Identified New Therapeutic Targets. PMID:29669821
Evolution of DNMT2 in drosophilids: Evidence for positive and purifying selection and insights into new protein (pathways) interactions. PMID:29668012
Sheep skeletal muscle transcriptome analysis reveals muscle growth regulatory lncRNAs. PMID:29666768
Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure. PMID:29664738
Isobaric Tag-Based Protein Profiling of a Nicotine-Treated Alpha7 Nicotinic Receptor-Null Human Haploid Cell Line. PMID:29663646
Pan-cancer analysis of somatic mutations and transcriptomes reveals common functional gene clusters shared by multiple cancer types. PMID:29662161
Role of MSC-derived galectin 3 in the AML microenvironment. PMID:29655803
Identification of Morus notabilis MADS-box genes and elucidation of the roles of MnMADS33 during endodormancy. PMID:29643336
In Silico Functional Networks Identified in Fish Nucleated Red Blood Cells by Means of Transcriptomic and Proteomic Profiling. PMID:29642539
Transcriptome Analysis of Acute Phase Liver Graft Injury in Liver Transplantation. PMID:29642405
iTRAQ Quantitative Proteomic Analysis of Vitreous from Patients with Retinal Detachment. PMID:29641463
Molecular characterization and expression profiling of BMP 3 gene in broiler and layer chicken. PMID:29637489
Clinical value of miR-182-5p in lung squamous cell carcinoma: a study combining data from TCGA, GEO, and RT-qPCR validation. PMID:29636077
Polylysine is a Proteostasis Network-Engaging Structural Determinant. PMID:29634277
Salivary proteome profiling of oral squamous cell carcinoma in a Hungarian population. PMID:29632809
Cross-talk between monocyte invasion and astrocyte proliferation regulates scarring in brain injury. PMID:29632244
Identification of Prognostic Biomarkers by Combined mRNA and miRNA Expression Microarray Analysis in Pancreatic Cancer. PMID:29631214
Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length. PMID:29627459
Cell cycle and complement inhibitors may be specific for treatment of spinal cord injury in aged and young mice: Transcriptomic analyses. PMID:29623939
Microglia activation in Niemann-Pick disease, type C1 is amendable to therapeutic intervention. PMID:29617956
TISSUES 2.0: an integrative web resource on mammalian tissue expression. PMID:29617745
Liver regeneration during the associating liver partition and portal vein ligation for staged hepatectomy procedure in Sus scrofa is positively modulated by stem cells. PMID:29616108
A multi-step transcriptional cascade underlies vascular regeneration in vivo. PMID:29615716
Signatures of Long-Term Balancing Selection in Human Genomes. PMID:29608730
Systematic Evaluation of Molecular Networks for Discovery of Disease Genes. PMID:29605183
A Structured Workflow for Mapping Human Sin3 Histone Deacetylase Complex Interactions Using Halo-MudPIT Affinity-Purification Mass Spectrometry. PMID:29599190
Identification of key genes and miRNAs associated with carotid atherosclerosis based on mRNA-seq data. PMID:29595698
Language and Cognitive Impairment Associated with a Novel p.Cys63Arg Change in the MED13L Transcriptional Regulator. PMID:29593475
TAILS N-terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation. PMID:29593093
Heterogeneous network propagation for herb target identification. PMID:29589568
Detangling PPI networks to uncover functionally meaningful clusters. PMID:29589565
Proteomic and bioinformatic pipeline to screen the ligands of S. pneumoniae interacting with human brain microvascular endothelial cells. PMID:29588455
SUMOylome Profiling Reveals a Diverse Array of Nuclear Targets Modified by the SUMO Ligase SIZ1 during Heat Stress. PMID:29588388
Gene expression analysis for pneumonia caused by Gram-positive bacterial infection. PMID:29581747
Proteomic Characterization of the Neural Ectoderm Fated Cell Clones in the Xenopus laevis Embryo by High-Resolution Mass Spectrometry. PMID:29578674
Integrated analysis of mRNA-seq and miRNA-seq for host susceptibilities to influenza A (H7N9) infection in inbred mouse lines. PMID:29564647
Efficient pathway enrichment and network analysis of GWAS summary data using GSA-SNP2. PMID:29562348
Measuring and Estimating the Effect Sizes of Copy Number Variants on General Intelligence in Community-Based Samples. PMID:29562078
Identification of key genes and pathways in human clear cell renal cell carcinoma (ccRCC) by co-expression analysis. PMID:29559845
Systematic analysis of the lysine malonylome in common wheat. PMID:29558883
Stress-related genes promote Edwardsiella ictaluri pathogenesis. PMID:29554143
Prognostic value of alcohol dehydrogenase mRNA expression in gastric cancer. PMID:29552190
Bivalent Chromatin Domains in Glioblastoma Reveal a Subtype-Specific Signature of Glioma Stem Cells. PMID:29549165
A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia. PMID:29547969
Molecular differences between mature and immature dental pulp cells: Bioinformatics and preliminary results. PMID:29545856
Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival. PMID:29545342
LMTK3 confers chemo-resistance in breast cancer. PMID:29540829
iDREM: Interactive visualization of dynamic regulatory networks. PMID:29538379
MetaGO: Predicting Gene Ontology of Non-homologous Proteins Through Low-Resolution Protein Structure Prediction and Protein-Protein Network Mapping. PMID:29534977
Chemokine expression in the early response to injury in human airway epithelial cells. PMID:29534074
Quantitative peptidomics of endogenous peptides involved in TGF-β1-induced epithelial mesenchymal transition of renal epithelial cells. PMID:29531806
The TRiC chaperonin controls reovirus replication through outer-capsid folding. PMID:29531365
CoA synthase regulates mitotic fidelity via CBP-mediated acetylation. PMID:29531224
Expression and regulation of avian beta-defensin 8 protein in immune tissues and cell lines of chickens. PMID:29531188
Predicted Arabidopsis Interactome Resource and Gene Set Linkage Analysis: A Transcriptomic Analysis Resource. PMID:29530937
Proteomic analysis of corneal endothelial cell-descemet membrane tissues reveals influence of insulin dependence and disease severity in type 2 diabetes mellitus. PMID:29529022
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay. PMID:29528287
Whole transcriptome profiling of Late-Onset Alzheimer's Disease patients provides insights into the molecular changes involved in the disease. PMID:29523845
Using genome wide association studies to identify common QTL regions in three different genetic backgrounds based on Iberian pig breed. PMID:29522525
Complex association patterns for inflammatory mediators in induced sputum from subjects with asthma. PMID:29520864
CD40 ligand deficiency causes functional defects of peripheral neutrophils that are improved by exogenous IFN-γ. PMID:29518426
Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma. PMID:29518416
Genetic polymorphisms of NOS2 and predisposition to fracture non-union: A case control study based on Han Chinese population. PMID:29518099
Novel Sequence Features of DNA Repair Genes/Proteins from Deinococcus Species Implicated in Protection from Oxidatively Generated Damage. PMID:29518000
Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma. PMID:29515771
Caloric Restriction Engages Hepatic RNA Processing Mechanisms in Rhesus Monkeys. PMID:29514073
Building protein-protein interaction networks for Leishmania species through protein structural information. PMID:29510668
Inhibitor of Differentiation-3 and Estrogenic Endocrine Disruptors: Implications for Susceptibility to Obesity and Metabolic Disorders. PMID:29507860
Phenotype-driven identification of epithelial signalling clusters. PMID:29507319
Proteomics of Aspergillus fumigatus Conidia-containing Phagolysosomes Identifies Processes Governing Immune Evasion. PMID:29507050
Wnt Signalling Drives Context-Dependent Differentiation or Proliferation in Neuroblastoma. PMID:29505958
FunGeneNet: a web tool to estimate enrichment of functional interactions in experimental gene sets. PMID:29504895
Joint study of two genome-wide association meta-analyses identified 20p12.1 and 20q13.33 for bone mineral density. PMID:29499414
From gene networks to drugs: systems pharmacology approaches for AUD. PMID:29497781
T-Cell Immunopeptidomes Reveal Cell Subtype Surface Markers Derived From Intracellular Proteins. PMID:29493099
Integrative functional analysis of super enhancer SNPs for coronary artery disease. PMID:29491472
The Druggable Pocketome of Corynebacterium diphtheriae: A New Approach for in silico Putative Druggable Targets. PMID:29487617
Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis. PMID:29487189
Ten hub genes associated with progression and prognosis of pancreatic carcinoma identified by co-expression analysis. PMID:29483831
MSD1 regulates pedicellate spikelet fertility in sorghum through the jasmonic acid pathway. PMID:29483511
Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β-Blockers. PMID:29478026
Text mining-based in silico drug discovery in oral mucositis caused by high-dose cancer therapy. PMID:29476419
Unexplored therapeutic opportunities in the human genome. PMID:29472638
Periosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin. PMID:29472541
Genomewide Transcriptional Responses of Iron-Starved Chlamydia trachomatis Reveal Prioritization of Metabolic Precursor Synthesis over Protein Translation. PMID:29468197
iTRAQ-Based Comparative Proteomic Analysis of Adult Schistosoma japonicum from Water Buffalo and Yellow Cattle. PMID:29467732
Proteome analysis of Aspergillus flavus isolate-specific responses to oxidative stress in relationship to aflatoxin production capability. PMID:29467403
High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds. PMID:29467300
SREBP2 contributes to cisplatin resistance in ovarian cancer cells. PMID:29466876
Proteomic analysis of the human retina reveals region-specific susceptibilities to metabolic- and oxidative stress-related diseases. PMID:29466423
Specialized plant biochemistry drives gene clustering in fungi. PMID:29463891
Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesis of the Yersinia-Containing Vacuole To Avoid Killing by Macrophages. PMID:29463656
BAG3 Overexpression and Cytoprotective Autophagy Mediate Apoptosis Resistance in Chemoresistant Breast Cancer Cells. PMID:29462756
Mendelian Disease Associations Reveal Novel Insights into Inflammatory Bowel Disease. PMID:29462399
Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy. PMID:29461977
Genome-Wide Analysis of the GRF Family Reveals Their Involvement in Abiotic Stress Response in Cassava. PMID:29461467
Genome-Wide Bimolecular Fluorescence Complementation-Based Proteomic Analysis of Toxoplasma gondii ROP18's Human Interactome Shows Its Key Role in Regulation of Cell Immunity and Apoptosis. PMID:29459857
AOP-DB: A database resource for the exploration of Adverse Outcome Pathways through integrated association networks. PMID:29454060
Identifying noncoding risk variants using disease-relevant gene regulatory networks. PMID:29453388
Mixed-species RNAseq analysis of human lymphoma cells adhering to mouse stromal cells identifies a core gene set that is also differentially expressed in the lymph node microenvironment of mantle cell lymphoma and chronic lymphocytic leukemia patients. PMID:29449436
Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor. PMID:29447339
A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts. PMID:29447159
Time- and polarity-dependent proteomic changes associated with homeostatic scaling at central synapses. PMID:29447110
Diverse Regulators of Human Ribosome Biogenesis Discovered by Changes in Nucleolar Number. PMID:29444442
Initiating Events in Direct Cardiomyocyte Reprogramming. PMID:29444441
Influence of Different Sugars and Initial pH on β-Glucan Formation by Lactobacillus brevis TMW 1.2112. PMID:29442149
Growing old, yet staying young: The role of telomeres in bats' exceptional longevity. PMID:29441358
Alanine Enhances Aminoglycosides-Induced ROS Production as Revealed by Proteomic Analysis. PMID:29441044
Liraglutide protects cardiac function in diabetic rats through the PPARα pathway. PMID:29440457
Gene expression profiling and bioinformatics analysis of hereditary gingival fibromatosis. PMID:29435271
Common module analysis reveals prospective targets and mechanisms of pediatric adrenocortical adenoma and carcinoma. PMID:29435068
Bioinformatical analysis of gene expression signatures of different glioma subtypes. PMID:29435008
Molecular dynamics simulations revealed structural differences among WRKY domain-DNA interaction in barley (Hordeum vulgare). PMID:29433424
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer's disease pathogenesis. PMID:29432188
Dissecting the biochemical architecture and morphological release pathways of the human platelet extracellular vesiculome. PMID:29427073
Friend virus limits adaptive cellular immune responses by imprinting a maturation-resistant and T helper type 2-biased immunophenotype in dendritic cells. PMID:29425215
Global view of a drug-sensitivity gene network. PMID:29423044
Systematic analysis of gene expression alterations and clinical outcomes of STAT3 in cancer. PMID:29423040
Comparative proteomics as a tool for identifying specific alterations within interferon response pathways in human glioblastoma multiforme cells. PMID:29416731
Substrate Binding Protein DppA1 of ABC Transporter DppBCDF Increases Biofilm Formation in Pseudomonas aeruginosa by Inhibiting Pf5 Prophage Lysis. PMID:29416528
Platelet procoagulant phenotype is modulated by a p38-MK2 axis that regulates RTN4/Nogo proximal to the endoplasmic reticulum: utility of pathway analysis. PMID:29412690
Role of the visual experience-dependent nascent proteome in neuronal plasticity. PMID:29412139
Host-Virus Protein Interaction Network Reveals the Involvement of Multiple Host Processes in the Life Cycle of Hepatitis E Virus. PMID:29404423
In-Depth Proteomic Characterization of Classical and Non-Classical Monocyte Subsets. PMID:29401756
Correlation analysis of mesenchymal-epithelial transition factor protein and human epidermal growth receptor 2 protein expression in 1479 cases of lung adenocarcinoma in China. PMID:29400000
Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis. PMID:29399633
Whole-Transcriptome Analysis of Mouse Models with MPTP-Induced Early Stages of Parkinson's Disease Reveals Stage-Specific Response of Transcriptome and a Possible Role of Myelin-Linked Genes in Neurodegeneration. PMID:29397556
hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage. PMID:29396485
Comparative phosphoproteomic analysis reveals signaling networks regulating monopolar and bipolar cytokinesis. PMID:29396449
Identification of methylated genes and miRNA signatures in nasopharyngeal carcinoma by bioinformatics analysis. PMID:29393436
Co-complex protein membership evaluation using Maximum Entropy on GO ontology and InterPro annotation. PMID:29390084
Transcriptomic responses to biotic stresses in Malus x domestica: a meta-analysis study. PMID:29386527
Angiogenesis and evading immune destruction are the main related transcriptomic characteristics to the invasive process of oral tongue cancer. PMID:29386520
Phosphoproteome profiling reveals critical role of JAK-STAT signaling in maintaining chemoresistance in breast cancer. PMID:29383118
New Targets for Zika Virus Determined by Human-Viral Interactomic: A Bioinformatics Approach. PMID:29379794
Molecular Genetic Analysis of Human Endometrial Mesenchymal Stem Cells That Survived Sublethal Heat Shock. PMID:29375621
Prospects for Fungal Bioremediation of Acidic Radioactive Waste Sites: Characterization and Genome Sequence of Rhodotorula taiwanensis MD1149. PMID:29375494
Systematic Analysis of mRNA and miRNA Expression of 3D-Cultured Neural Stem Cells (NSCs) in Spaceflight. PMID:29375320
Proteomic analysis reveals distinctive protein profiles involved in CD8+ T cell-mediated murine autoimmune cholangitis. PMID:29375127
Screening of Potential Genes and Transcription Factors of Postoperative Cognitive Dysfunction via Bioinformatics Methods. PMID:29374768
Global Quantitative Proteomics reveal Deregulation of Cytoskeletal and Apoptotic Signalling Proteins in Oral Tongue Squamous Cell Carcinoma. PMID:29371635
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors. PMID:29371290
Differential Proteomics for Distinguishing Ischemic Stroke from Controls: a Pilot Study of the SpecTRA Project. PMID:29368175
Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials. PMID:29367740
The Identification of Key Genes and Pathways in Glioma by Bioinformatics Analysis. PMID:29362722
Choriodecidual leukocytes display a unique gene expression signature in spontaneous labor at term. PMID:29362510
ATP-mediated Events in Peritubular Cells Contribute to Sterile Testicular Inflammation. PMID:29362497
Respiromics - An integrative analysis linking mitochondrial bioenergetics to molecular signatures. PMID:29361498
Tie2 protects the vasculature against thrombus formation in systemic inflammation. PMID:29360642
FoxP2 isoforms delineate spatiotemporal transcriptional networks for vocal learning in the zebra finch. PMID:29360038
Quantitative Proteomics After Spinal Cord Injury (SCI) in a Regenerative and a Nonregenerative Stage in the Frog Xenopus laevis. PMID:29358338
Integration of multi-omics data for integrative gene regulatory network inference. PMID:29354189
Ultrastructural Localization and Molecular Associations of HCV Capsid Protein in Jurkat T Cells. PMID:29354102
Robust phenotype prediction from gene expression data using differential shrinkage of co-regulated genes. PMID:29352257
The silent healer: miR-205-5p up-regulation inhibits epithelial to mesenchymal transition in colon cancer cells by indirectly up-regulating E-cadherin expression. PMID:29352232
Comparative salivary proteomics analysis of children with and without dental caries using the iTRAQ/MRM approach. PMID:29351798
A novel genomic signature predicting FDG uptake in diverse metastatic tumors. PMID:29349517
Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease. PMID:29348827
Investigating the Mechanisms of Action of Depside Salt from Salvia miltiorrhiza Using Bioinformatic Analysis. PMID:29348768
Comprehensive list of SUMO targets in Caenorhabditis elegans and its implication for evolutionary conservation of SUMO signaling. PMID:29348603
Identification of Secreted Proteins Involved in Nonspecific dsRNA-Mediated Lutzomyia longipalpis LL5 Cell Antiviral Response. PMID:29346269
Phosphoproteomics-Based Profiling of Kinase Activities in Cancer Cells. PMID:29344887
Discovering Altered Regulation and Signaling Through Network-based Integration of Transcriptomic, Epigenomic, and Proteomic Tumor Data. PMID:29344883
Identification of key pathways and genes in TP53 mutation acute myeloid leukemia: evidence from bioinformatics analysis. PMID:29343974
LocText: relation extraction of protein localizations to assist database curation. PMID:29343218
Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer. PMID:29342159
Loss of disease tolerance during Citrobacter rodentium infection is associated with impaired epithelial differentiation and hyperactivation of T cell responses. PMID:29339782
Genetic Variants in Immune-Related Pathways and Breast Cancer Risk in African American Women in the AMBER Consortium. PMID:29339359
Molecular and functional signatures in a novel Alzheimer's disease mouse model assessed by quantitative proteomics. PMID:29338754
Donor age affects proteome composition of tenocyte-derived engineered tendon. PMID:29338716
Transcriptional responses of Escherichia coli during recovery from inorganic or organic mercury exposure. PMID:29338696
Network-Based Methods for Identifying Key Active Proteins in the Extracellular Electron Transfer Process in Shewanella oneidensis MR-1. PMID:29337910
A novel approach for correction of crosstalk effects in pathway analysis and its application in osteoporosis research. PMID:29330445
Bioinformatic identification of chemoresistance-associated microRNAs in breast cancer based on microarray data. PMID:29328395
ERBB3-Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency-Associated-4 (DPPA4) Cofactor in Human Pluripotent Cells. PMID:29327467
Nonstructural proteins nsp2TF and nsp2N of porcine reproductive and respiratory syndrome virus (PRRSV) play important roles in suppressing host innate immune responses. PMID:29325778
Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection. PMID:29325153
Prohibitin plays a critical role in Enterovirus 71 neuropathogenesis. PMID:29324904
ModuleDiscoverer: Identification of regulatory modules in protein-protein interaction networks. PMID:29323246
Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata. PMID:29323127
Dysregulation of AKT3 along with a small panel of mRNAs stratifies high-grade serous ovarian cancer from both normal epithelia and benign tumor tissues. PMID:29321820
The PPI network analysis of mRNA expression profile of uterus from primary dysmenorrheal rats. PMID:29321498
Identification and Characterization of Sindbis Virus RNA-Host Protein Interactions. PMID:29321325
Meta-analysis of human gene expression in response to Mycobacterium tuberculosis infection reveals potential therapeutic targets. PMID:29321020
A census of P. longum's phytochemicals and their network pharmacological evaluation for identifying novel drug-like molecules against various diseases, with a special focus on neurological disorders. PMID:29320554
Integrated omics dissection of proteome dynamics during cardiac remodeling. PMID:29317621
Assessing the Performances of Protein Function Prediction Algorithms from the Perspectives of Identification Accuracy and False Discovery Rate. PMID:29316706
Systematic assessment of cervical cancer initiation and progression uncovers genetic panels for deep learning-based early diagnosis and proposes novel diagnostic and prognostic biomarkers. PMID:29312619
Characterization of Foodborne Strains of Staphylococcus aureus by Shotgun Proteomics: Functional Networks, Virulence Factors and Species-Specific Peptide Biomarkers. PMID:29312172
Putative functional genes in idiopathic dilated cardiomyopathy. PMID:29311597
LINE-1 protein localization and functional dynamics during the cell cycle. PMID:29309036
PIVOT: platform for interactive analysis and visualization of transcriptomics data. PMID:29304726
Biomarkers for tissue engineering of the tendon-bone interface. PMID:29298298
Refine gene functional similarity network based on interaction networks. PMID:29297381
The node-weighted Steiner tree approach to identify elements of cancer-related signaling pathways. PMID:29297291
CUFID-query: accurate network querying through random walk based network flow estimation. PMID:29297279
The pathogenesis of diclofenac induced immunoallergic hepatitis in a canine model of liver injury. PMID:29296203
Modularity Facilitates Flexible Tuning of Plastic and Evolutionary Gene Expression Responses during Early Divergence. PMID:29293993
Evolution of DDB1-binding WD40 (DWD) in the viridiplantae. PMID:29293590
Identification of Host Defense-Related Proteins Using Label-Free Quantitative Proteomic Analysis of Milk Whey from Cows with Staphylococcus aureus Subclinical Mastitis. PMID:29283389
Affinity purification mass spectrometry analysis of PD-1 uncovers SAP as a new checkpoint inhibitor. PMID:29282323
Resistant and susceptible chicken lines show distinctive responses to Newcastle disease virus infection in the lung transcriptome. PMID:29281979
Cancer Associated Fibroblasts: The Architects of Stroma Remodeling. PMID:29280568
Altered gene expression and metabolism in fetal umbilical cord mesenchymal stem cells correspond with differences in 5-month-old infant adiposity gain. PMID:29273781
A network-based meta-analysis for characterizing the genetic landscape of human aging. PMID:29270911
Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy. PMID:29269392
Sequential feature selection and inference using multi-variate random forests. PMID:29267851
Disturbed Glucose Metabolism in Rat Neurons Exposed to Cerebrospinal Fluid Obtained from Multiple Sclerosis Subjects. PMID:29267205
Identification and expression of CAMTA genes in Populus trichocarpa under biotic and abiotic stress. PMID:29263356
Evaluation of the association of UBASH3A and SYNGR1 with rheumatoid arthritis and disease activity and severity in Han Chinese. PMID:29262569
Prioritizing chronic obstructive pulmonary disease (COPD) candidate genes in COPD-related networks. PMID:29262568
Sustained activation of the AKT/mTOR and MAP kinase pathways mediate resistance to the Src inhibitor, dasatinib, in thyroid cancer. PMID:29262541
TSC1 Mutations in Keratoconus Patients With or Without Tuberous Sclerosis. PMID:29261847
Integrative network-based approach identifies central genetic and transcriptomic elements in triple-negative breast cancer. PMID:29260344
Functional analysis of Plasmodium falciparum subpopulations associated with artemisinin resistance in Cambodia. PMID:29258508
A biological network-based regularized artificial neural network model for robust phenotype prediction from gene expression data. PMID:29258445
Deciphering the Relationship between Obesity and Various Diseases from a Network Perspective. PMID:29258237
Identification of key pathways and genes in Barrett's esophagus using integrated bioinformatics methods. PMID:29257318
Gene Network Analysis of Interstitial Macrophages After Treatment with Induced Pluripotent Stem Cells Secretome (iPSC-cm) in the Bleomycin Injured Rat Lung. PMID:29256173
A sodium binding system alleviates acute salt stress during seawater acclimation in eels. PMID:29255617
Novel Method for Noninvasive Sampling of the Distal Airspace in Acute Respiratory Distress Syndrome. PMID:29253353
HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway. PMID:29249663
Proteomic Characterization of Prostate Cancer to Distinguish Nonmetastasizing and Metastasizing Primary Tumors and Lymph Node Metastases. PMID:29248718
Identification of Sertoli cell-specific transcripts in the mouse testis and the role of FSH and androgen in the control of Sertoli cell activity. PMID:29246116
Cryptogenic cholestasis in young and adults: ATP8B1, ABCB11, ABCB4, and TJP2 gene variants analysis by high-throughput sequencing. PMID:29238877
Unravelling Protein-Protein Interaction Networks Linked to Aliphatic and Indole Glucosinolate Biosynthetic Pathways in Arabidopsis. PMID:29238354
Relative Quantitative Proteomic Analysis of Brucella abortus Reveals Metabolic Adaptation to Multiple Environmental Stresses. PMID:29238329
Fibroblasts play a potential role in bone destruction via osteopontin related caldesmon expression and polymerization in human non-functioning pituitary adenomas. PMID:29235490
Identification of Biomarkers Correlated with the TNM Staging and Overall Survival of Patients with Bladder Cancer. PMID:29234286
Phosphoproteomics reveals network rewiring to a pro-adhesion state in annexin-1-deficient mammary epithelial cells. PMID:29233185
Functional and evolutionary analysis of Korean bob-tailed native dog using whole-genome sequencing data. PMID:29230066
Ensemble Modeling Approach Targeting Heterogeneous RNA-Seq data: Application to Melanoma Pseudogenes. PMID:29229974
Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex. PMID:29229923
Comparison of Echinococcus multilocularis and Echinococcus granulosus hydatid fluid proteome provides molecular strategies for specialized host-parasite interactions. PMID:29228589
Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells. PMID:29228002
Isolation and Molecular Characterization of Amniotic Fluid-Derived Mesenchymal Stem Cells Obtained from Caesarean Sections. PMID:29225627
Insights from the protein-protein interaction network analysis of Mycobacterium tuberculosis toxin-antitoxin systems. PMID:29225431
Deciphering transcriptional regulation in human embryonic stem cells specified towards a trophoblast fate. PMID:29222466
Exploring digenic inheritance in arrhythmogenic cardiomyopathy. PMID:29221435
Plasma-derived extracellular vesicle proteins as a source of biomarkers for lung adenocarcinoma. PMID:29221141
MiRIAD update: using alternative polyadenylation, protein interaction network analysis and additional species to enhance exploration of the role of intragenic miRNAs and their host genes. PMID:29220447
LeishDB: a database of coding gene annotation and non-coding RNAs in Leishmania braziliensis. PMID:29220437
Expression profile analysis of long non-coding RNA in acute myeloid leukemia by microarray and bioinformatics. PMID:29220122
Large-scale analysis of disease pathways in the human interactome. PMID:29218874
Expanding horizons: new roles for non-canonical RNA-binding proteins in cancer. PMID:29216518
Identification of Candidate Casein Kinase 2 Substrates in Mitosis by Quantitative Phosphoproteomics. PMID:29214152
Transcriptional survey of alveolar macrophages in a murine model of chronic granulomatous inflammation reveals common themes with human sarcoidosis. PMID:29212802
Gene gravity-like algorithm for disease gene prediction based on phenotype-specific network. PMID:29212543
Changes in Neuronal Signaling and Cell Stress Response Pathways are Associated with a Multigenic Response of Drosophila melanogaster to DDT Selection. PMID:29211847
Regulation of mesenchymal signaling in palatal mucosa differentiation. PMID:29209830
A Perspective on Extracellular Vesicles Proteomics. PMID:29209607
Co-expression network analysis identified FCER1G in association with progression and prognosis in human clear cell renal cell carcinoma. PMID:29209141
A novel correlation between ATP5A1 gene expression and progression of human clear cell renal cell carcinoma identified by co‑expression analysis. PMID:29207195
Potential role of microRNA‑223‑3p in the tumorigenesis of hepatocellular carcinoma: A comprehensive study based on data mining and bioinformatics. PMID:29207133
Use of methylation profiling to identify significant differentially methylated genes in bone marrow mesenchymal stromal cells from acute myeloid leukemia. PMID:29207054
Repository corticotrophin injection exerts direct acute effects on human B cell gene expression distinct from the actions of glucocorticoids. PMID:29205315
Genetic Variation and Gene Expression Levels of Tight Junction Genes Indicates Relationships Between PTEN as well as MAGI1 and Microscopic Colitis. PMID:29204743
Uncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology Approach. PMID:29203792
Explorative visual analytics on interval-based genomic data and their metadata. PMID:29202689
A network pharmacology approach to investigate the pharmacological effects of Guizhi Fuling Wan on uterine fibroids. PMID:29201170
Resetting the Yeast Epigenome with Human Nucleosomes. PMID:29198523
A systems medicine approach reveals disordered immune system and lipid metabolism in multiple sclerosis patients. PMID:29194580
The target landscape of clinical kinase drugs. PMID:29191878
A proximity-based graph clustering method for the identification and application of transcription factor clusters. PMID:29187152
The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery. PMID:29186335
Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches. PMID:29186305
Computational systems biology approaches for Parkinson's disease. PMID:29185073
A multiregional proteomic survey of the postnatal human brain. PMID:29184206
Identification of key genes and pathways associated with neuropathic pain in uninjured dorsal root ganglion by using bioinformatic analysis. PMID:29180893
Phosphoproteomics of cAMP signaling of Bordetella adenylate cyclase toxin in mouse dendritic cells. PMID:29176673
Global landscape of cell envelope protein complexes in Escherichia coli. PMID:29176613
COGNAT: a web server for comparative analysis of genomic neighborhoods. PMID:29166914
ADAGE signature analysis: differential expression analysis with data-defined gene sets. PMID:29166858
A Cell-Line-Specific Atlas of PARP-Mediated Protein Asp/Glu-ADP-Ribosylation in Breast Cancer. PMID:29166620
Identification of molecular mechanisms of glutamine in pancreatic cancer. PMID:29163679
The cAMP responsive element-binding (CREB)-1 gene increases risk of major psychiatric disorders. PMID:29158582
Using molecular functional networks to manifest connections between obesity and obesity-related diseases. PMID:29156709
RARβ2-dependent signaling represses neuronal differentiation in mouse ES cells. PMID:29154149
Association of Omics Features with Histopathology Patterns in Lung Adenocarcinoma. PMID:29153840
Functional network analysis of gene-phenotype connectivity associated with temozolomide. PMID:29152101
Deep RNAseq indicates protective mechanisms of cold-tolerant indica rice plants during early vegetative stage. PMID:29151156
Constructing Genetic Networks using Biomedical Literature and Rare Event Classification. PMID:29150626
Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness. PMID:29149419
GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. PMID:29146897
Scrambled eggs: Proteomic portraits and novel biomarkers of egg quality in zebrafish (Danio rerio). PMID:29145436
Sub-minute Phosphoregulation of Cell Cycle Systems during Plasmodium Gamete Formation. PMID:29141230
Utility of miR‑133a‑3p as a diagnostic indicator for hepatocellular carcinoma: An investigation combined with GEO, TCGA, meta‑analysis and bioinformatics. PMID:29138825
The industrial anaerobe Clostridium acetobutylicum uses polyketides to regulate cellular differentiation. PMID:29138399
Innate Cell-Mediated Cytotoxic Activity of European Sea Bass Leucocytes Against Nodavirus-Infected Cells: A Functional and RNA-seq Study. PMID:29133947
Comprehensive genomic analysis of the CNGC gene family in Brassica oleracea: novel insights into synteny, structures, and transcript profiles. PMID:29132315
Non-monotonic Changes in Progenitor Cell Behavior and Gene Expression during Aging of the Adult V-SVZ Neural Stem Cell Niche. PMID:29129683
Spatially-Resolved Top-down Proteomics Bridged to MALDI MS Imaging Reveals the Molecular Physiome of Brain Regions. PMID:29122912
Entity recognition in the biomedical domain using a hybrid approach. PMID:29122011
Transcriptomic analyses reveal the underlying pro-malignant functions of PTHR1 for osteosarcoma via activation of Wnt and angiogenesis pathways. PMID:29121993
Molecular spectrum of secretome regulates the relative hepatogenic potential of mesenchymal stem cells from bone marrow and dental tissue. PMID:29118330
Lung epithelial response to cigarette smoke and modulation by the nicotinic alpha 7 receptor. PMID:29117258
Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics). PMID:29113996
A novel method to identify differential pathways in uterine leiomyomata based on network strategy. PMID:29113205
Size-based detection of sarcoma circulating tumor cells and cell clusters. PMID:29108279
Comprehensive bioinformatics analysis of the characterization and determination underlying mechanisms of over-expression and co-expression of genes residing on 20q in colorectal cancer. PMID:29108255
Insight into glucocorticoid receptor signalling through interactome model analysis. PMID:29107989
MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma. PMID:29104726
Predicted Cold Shock Proteins from the Extremophilic Bacterium Deinococcus maricopensis and Related Deinococcus Species. PMID:29098004
Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation. PMID:29093484
Maternal obesity and increased neonatal adiposity correspond with altered infant mesenchymal stem cell metabolism. PMID:29093265
Evaluation of miRNA-196a2 and apoptosis-related target genes: ANXA1, DFFA and PDCD4 expression in gastrointestinal cancer patients: A pilot study. PMID:29091952
Quantitative proteomic Analysis Reveals up-regulation of caveolin-1 in FOXP3-overexpressed human gastric cancer cells. PMID:29089565
Evolution of the Aux/IAA Gene Family in Hexaploid Wheat. PMID:29085968
Characterizations of PMCA2-interacting complex and its role as a calcium oxalate crystal-binding protein. PMID:29085954
Multi-omics Comparative Analysis Reveals Multiple Layers of Host Signaling Pathway Regulation by the Gut Microbiota. PMID:29085914
Regulation of NF-κB by the p105-ABIN2-TPL2 complex and RelAp43 during rabies virus infection. PMID:29084252
A Systematic In-silico Analysis of Helicobacter pylori Pathogenic Islands for Identification of Novel Drug Target Candidates. PMID:29081700
Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets. PMID:29081603
Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid Growth Factor Receptor (OGFr). PMID:29079719
Affinity proteomics reveals extensive phosphorylation of the Brassica chromosome axis protein ASY1 and a network of associated proteins at prophase I of meiosis. PMID:29078019
A Network Pharmacology Approach to Determine the Active Components and Potential Targets of Curculigo Orchioides in the Treatment of Osteoporosis. PMID:29074841
Fusing multiple protein-protein similarity networks to effectively predict lncRNA-protein interactions. PMID:29072138
A Systems Biology Approach Provides Deeper Insights into Differentially Expressed Genes in Taxane-Anthracycline Chemoresistant and Non-Resistant Breast Cancers. PMID:29072056
Transcriptomic response to thermal and salinity stress in introduced and native sympatric Palaemon caridean shrimps. PMID:29070787
Understanding Tissue-Specific Gene Regulation. PMID:29069589
Identification of Gene Expression Changes in the Aorta of ApoE Null Mice Fed a High-Fat Diet. PMID:29064389
The Challenge of Human Spermatozoa Proteome: A Systematic Review. PMID:29062791
Structural and functional characterization of the Helicobacter pylori cytidine 5'-monophosphate-pseudaminic acid synthase PseF: molecular insight into substrate recognition and catalysis mechanism. PMID:29062238
Comparative Network Analysis of Patients with Non-Small Cell Lung Cancer and Smokers for Representing Potential Therapeutic Targets. PMID:29062084
Confronting the catalytic dark matter encoded by sequenced genomes. PMID:29059321
SalmoNet, an integrated network of ten Salmonella enterica strains reveals common and distinct pathways to host adaptation. PMID:29057095
Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis. PMID:29050298
Identification of core genes and outcome in gastric cancer using bioinformatics analysis. PMID:29050278
KIT performed as a driver gene candidate affecting the survival status of patients with stomach adenocarcinoma. PMID:29050270
NRF2-regulated metabolic gene signature as a prognostic biomarker in non-small cell lung cancer. PMID:29050246
The Early Dendritic Cell Signaling Induced by Virulent Francisella tularensis Strain Occurs in Phases and Involves the Activation of Extracellular Signal-Regulated Kinases (ERKs) and p38 In the Later Stage. PMID:29046388
Host transcription factor Speckled 110 kDa (Sp110), a nuclear body protein, is hijacked by hepatitis B virus protein X for viral persistence. PMID:29046350
The neonicotinoid insecticide Clothianidin adversely affects immune signaling in a human cell line. PMID:29044138
Prediction of Protein Complexes in Trypanosoma brucei by Protein Correlation Profiling Mass Spectrometry and Machine Learning. PMID:29042480
The online Tabloid Proteome: an annotated database of protein associations. PMID:29040688
MCM2-regulated functional networks in lung cancer by multi-dimensional proteomic approach. PMID:29038488
Blood-Based Protein Changes in Childhood Are Associated With Increased Risk for Later Psychotic Disorder: Evidence From a Nested Case-Control Study of the ALSPAC Longitudinal Birth Cohort. PMID:29036721
Plasmodium falciparum specific helicase 3 is nucleocytoplasmic protein and unwinds DNA duplex in 3' to 5' direction. PMID:29030567
DeepGO: predicting protein functions from sequence and interactions using a deep ontology-aware classifier. PMID:29028931
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. PMID:29026089
Synteny analysis of genes and distribution of loci controlling oil content and fatty acid profile based on QTL alignment map in Brassica napus. PMID:29025408
Prediction of Human Phenotype Ontology terms by means of hierarchical ensemble methods. PMID:29025394
PICKLE 2.0: A human protein-protein interaction meta-database employing data integration via genetic information ontology. PMID:29023571
BeWith: A Between-Within method to discover relationships between cancer modules via integrated analysis of mutual exclusivity, co-occurrence and functional interactions. PMID:29023534
Systematic, network-based characterization of therapeutic target inhibitors. PMID:29023443
Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors. PMID:29020998
Recent Advances in the Systems Biology of Aging. PMID:29020802
A novel network analysis approach reveals DNA damage, oxidative stress and calcium/cAMP homeostasis-associated biomarkers in frontotemporal dementia. PMID:29020091
Genotype combination contributes to psoriasis: An exhaustive algorithm perspective. PMID:29020033
DMRTC2, PAX7, BRACHYURY/T and TERT Are Implicated in Male Germ Cell Development Following Curative Hormone Treatment for Cryptorchidism-Induced Infertility. PMID:29019938
Network Diffusion-Based Prioritization of Autism Risk Genes Identifies Significantly Connected Gene Modules. PMID:28993790
Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses. PMID:28993767
Polypharmacology-based ceritinib repurposing using integrated functional proteomics. PMID:28991240
DOMINO: Using Machine Learning to Predict Genes Associated with Dominant Disorders. PMID:28985496
Genome-wide mapping of large deletions and their population-genetic properties in dairy cattle. PMID:28985340
Roles of alternative splicing in modulating transcriptional regulation. PMID:28984199
Ion Mobility-Mass Spectrometry Reveals Evidence of Specific Complex Formation between Human Histone Deacetylase 8 and Poly-r(C)-binding Protein 1. PMID:28983190
Multiplexed Temporal Quantification of the Exercise-regulated Plasma Peptidome. PMID:28982716
RUNX2 expression in thyroid and breast cancer requires the cooperation of three non-redundant enhancers under the control of BRD4 and c-JUN. PMID:28981843
The Encyclopedia of Proteome Dynamics: a big data ecosystem for (prote)omics. PMID:28981707
Individual-specific edge-network analysis for disease prediction. PMID:28981699
A Unique TGFB1-Driven Genomic Program Links Astrocytosis, Low-Grade Inflammation and Partial Demyelination in Spinal Cord Periplaques from Progressive Multiple Sclerosis Patients. PMID:28981455
Protein-protein interactions leave evolutionary footprints: High molecular coevolution at the core of interfaces. PMID:28980349
Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein. PMID:28978044
Targeted exome sequencing of Korean triple-negative breast cancer reveals homozygous deletions associated with poor prognosis of adjuvant chemotherapy-treated patients. PMID:28977883
Integrated transcriptomic analysis of distance-related field cancerization in rectal cancer patients. PMID:28977850
Functional 5' UTR motif discovery with LESMoN: Local Enrichment of Sequence Motifs in biological Networks. PMID:28977652
Multi-dimensional histone methylations for coordinated regulation of gene expression under hypoxia. PMID:28977425
Fast hyperbaric decompression after heliox saturation altered the brain proteome in rats. PMID:28977037
Meta-analysis of transcriptomic datasets identifies genes enriched in the mammalian circadian pacemaker. PMID:28973476
Sp110 enhances macrophage resistance to Mycobacterium tuberculosis via inducing endoplasmic reticulum stress and inhibiting anti-apoptotic factors. PMID:28969051
Identification of genes and pathways in nasopharyngeal carcinoma by bioinformatics analysis. PMID:28969025
Interactive network visualization in Jupyter notebooks: visJS2jupyter. PMID:28968701
Drug enrichment and discovery from schizophrenia genome-wide association results: an analysis and visualisation approach. PMID:28963561
Radiation alters the cargo of exosomes released from squamous head and neck cancer cells to promote migration of recipient cells. PMID:28963552
A transcriptome-based protein network that identifies new therapeutic targets in colorectal cancer. PMID:28962550
Network-Based Identification of Adaptive Pathways in Evolved Ethanol-Tolerant Bacterial Populations. PMID:28961727
Phosphoproteomics Profiling of Nonsmall Cell Lung Cancer Cells Treated with a Novel Phosphatase Activator. PMID:28961369
Identification of genetic networks that act in the somatic cells of the testis to mediate the developmental program of spermatogenesis. PMID:28957323
Inference and interrogation of a coregulatory network in the context of lipid accumulation in Yarrowia lipolytica. PMID:28955503
Comparative Genomics of Ralstonia solanacearum Identifies Candidate Genes Associated with Cool Virulence. PMID:28955357
A proteomics approach to identify targets of the ubiquitin-like molecule Urm1 in Drosophila melanogaster. PMID:28953965
Pathway Interaction Network Analysis Identifies Dysregulated Pathways in Human Monocytes Infected by Listeria monocytogenes. PMID:28951764
Quantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to Pulmonary Aspergillus fumigatus Infection. PMID:28951444
HTS-Net: An integrated regulome-interactome approach for establishing network regulation models in high-throughput screenings. PMID:28949986
Identification of hub genes involved in the development of hepatocellular carcinoma by transcriptome sequencing. PMID:28947976
Relating protein functional diversity to cell type number identifies genes that determine dynamic aspects of chromatin organisation as potential contributors to organismal complexity. PMID:28945800
Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis. PMID:28945738
Integrated strategy of differentially expressed genes associated with ulcerative colitis. PMID:28944823
Network module identification-A widespread theoretical bias and best practices. PMID:28941788
Evaluation of autoantibody signatures in meningioma patients using human proteome arrays. PMID:28938569
Characterization of Soft Amyloid Cores in Human Prion-Like Proteins. PMID:28935930
Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in Asthma. PMID:28933920
A computational method using the random walk with restart algorithm for identifying novel epigenetic factors. PMID:28932904
Transcriptomic and bioinformatics analysis of the early time-course of the response to prostaglandin F2 alpha in the bovine corpus luteum. PMID:28932774
Cross-ethnic meta-analysis identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. PMID:28931804
Discovering the miR-26a-5p Targetome in Prostate Cancer Cells. PMID:28928862
A systematic review and integrative approach to decode the common molecular link between levodopa response and Parkinson's disease. PMID:28927418
Discovery of Tamoxifen and N-Desmethyl Tamoxifen Protein Targets in MCF-7 Cells Using Large-Scale Protein Folding and Stability Measurements. PMID:28927269
Exploring the anti-proliferative activity of Pelargonium sidoides DC with in silico target identification and network pharmacology. PMID:28924942
Within-breed and multi-breed GWAS on imputed whole-genome sequence variants reveal candidate mutations affecting milk protein composition in dairy cattle. PMID:28923017
Backward genotype-transcript-phenotype association mapping. PMID:28917724
Phosphoproteomics reveals that glycogen synthase kinase-3 phosphorylates multiple splicing factors and is associated with alternative splicing. PMID:28916722
Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes metastasis-related properties via TGFβ2/TβR and CD44 in MDA-MB-231 breast cancer cells. PMID:28915803
Mitochondrial protein 18 (MTP18) plays a pro-apoptotic role in chemotherapy-induced gastric cancer cell apoptosis. PMID:28915614
DNA methylation profiling reveals common signatures of tumorigenesis and defines epigenetic prognostic subtypes of canine Diffuse Large B-cell Lymphoma. PMID:28912427
Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mechanisms. PMID:28912176
MCbiclust: a novel algorithm to discover large-scale functionally related gene sets from massive transcriptomics data collections. PMID:28911113
Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer. PMID:28904337
Exploring the Human-Nipah Virus Protein-Protein Interactome. PMID:28904190
The Long-Lasting Rodenticide Brodifacoum Induces Neuropathology in Adult Male Rats. PMID:28903499
Systematic analysis of coronary artery disease datasets revealed the potential biomarker and treatment target. PMID:28903366
Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance. PMID:28902459
Screening critical genes associated with malignant glioma using bioinformatics analysis. PMID:28901452
Whole Wiskott‑Aldrich syndrome protein gene deletion identified by high throughput sequencing. PMID:28901403
Screening candidate microRNA-mRNA regulatory pairs for predicting the response to chemoradiotherapy in rectal cancer by a bioinformatics approach. PMID:28900297
Unravelling the biology of chromatin in health and cancer using proteomic approaches. PMID:28895440
Identification of genes associated with primary open-angle glaucoma by bioinformatics approach. PMID:28894971
Predicted networks of protein-protein interactions in Stegodyphus mimosarum by cross-species comparisons. PMID:28893204
A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma. PMID:28892521
Monitoring storage induced changes in the platelet proteome employing label free quantitative mass spectrometry. PMID:28887518
Impaired response of the bronchial epithelium to inflammation characterizes severe equine asthma. PMID:28886691
SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms. PMID:28883622
Dissection of iron signaling and iron accumulation by overexpression of subgroup Ib bHLH039 protein. PMID:28883478
Incorporating interaction networks into the determination of functionally related hit genes in genomic experiments with Markov random fields. PMID:28881978
Integrated expression profiles analysis reveals novel predictive biomarker in pancreatic ductal adenocarcinoma. PMID:28881752
RNA Sequencing Uncovers Molecular Mechanisms Underlying Pathological Complete Response to Chemotherapy in Patients with Operable Breast Cancer. PMID:28880852
Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes. PMID:28877242
PrePhyloPro: phylogenetic profile-based prediction of whole proteome linkages. PMID:28875072
Integrated Analysis of Copy Number Variations and Gene Expression Profiling in Hepatocellular carcinoma. PMID:28874807
A chloroplast thylakoid lumen protein is required for proper photosynthetic acclimation of plants under fluctuating light environments. PMID:28874535
Potential Roles of Intrinsic Disorder in Maternal-Effect Proteins Involved in the Maintenance of DNA Methylation. PMID:28869544
Characterization of feedback-resistant mevalonate kinases from the methanogenic archaeons Methanosaeta concilii and Methanocella paludicola. PMID:28869407
Antitumor activity and expression profiles of genes induced by sulforaphane in human melanoma cells. PMID:28864908
Clinical significance and prospective molecular mechanism of MALAT1 in pancreatic cancer exploration: a comprehensive study based on the GeneChip, GEO, Oncomine, and TCGA databases. PMID:28860807
Structural and Functional View of Polypharmacology. PMID:28860623
Proteome-wide acetylation dynamics in human cells. PMID:28860605
Genetic association study of common variants in TGFB1 and IL-6 with developmental dysplasia of the hip in Han Chinese population. PMID:28860542
Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells. PMID:28860483
Reduced generation of lung tissue-resident memory T cells during infancy. PMID:28855242
Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells. PMID:28854368
HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection. PMID:28854257
iTRAQ-based proteomics monitors the withering dynamics in postharvest leaves of tea plant (Camellia sinensis). PMID:28852881
Investigation of host-pathogen interaction between Burkholderia pseudomallei and autophagy-related protein LC3 using hydrophobic chromatography-based technique. PMID:28852470
Proteomic and network analysis of human serum albuminome by integrated use of quick crosslinking and two-step precipitation. PMID:28851998
Comprehensive Analyses of Tissue-Specific Networks with Implications to Psychiatric Diseases. PMID:28849569
Analysis of gene expression profiling variations induced by hsa‑miR‑145‑5p‑overexpression in laryngeal squamous cell carcinoma cell line Tu‑177. PMID:28849105
Downregulation of miR‑136‑5p in hepatocellular carcinoma and its clinicopathological significance. PMID:28849100
Preterm labor in the absence of acute histologic chorioamnionitis is characterized by cellular senescence of the chorioamniotic membranes. PMID:28847437
Novel and ultra-rare damaging variants in neuropeptide signaling are associated with disordered eating behaviors. PMID:28846695
Docking-based modeling of protein-protein interfaces for extensive structural and functional characterization of missense mutations. PMID:28841721
Auxin Response Factor Genes Repertoire in Mulberry: Identification, and Structural, Functional and Evolutionary Analyses. PMID:28841197
Evolutionarily Conserved Alternative Splicing Across Monocots. PMID:28839042
Retinal and choroidal angiogenesis: a review of new targets. PMID:28835854
Nevirapine induced mitochondrial dysfunction in HepG2 cells. PMID:28835669
Uncover the Underlying Mechanism of Drug-Induced Myopathy by Using Systems Biology Approaches. PMID:28831389
Characterization of In Vivo Resistance to Osimertinib and JNJ-61186372, an EGFR/Met Bispecific Antibody, Reveals Unique and Consensus Mechanisms of Resistance. PMID:28830985
Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS. PMID:28827549
Identification of Nidogen 1 as a lung metastasis protein through secretome analysis. PMID:28827399
Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins. PMID:28826723
Construction of an integrated gene regulatory network link to stress-related immune system in cattle. PMID:28825201
Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing. PMID:28824170
K+ deficiency caused defects in renal tubular cell proliferation, oxidative stress response, tissue repair and tight junction integrity, but enhanced energy production, proteasome function and cellular K+ uptake. PMID:28820294
Biosemantics guided gene expression profiling of Sjögren's syndrome: a comparative analysis with systemic lupus erythematosus and rheumatoid arthritis. PMID:28818099
Overexpression of Topoisomerase 2-Alpha Confers a Poor Prognosis in Pancreatic Adenocarcinoma Identified by Co-Expression Analysis. PMID:28815403
Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations. PMID:28814792
Cancerouspdomains: comprehensive analysis of cancer type-specific recurrent somatic mutations in proteins and domains. PMID:28814324
eDGAR: a database of Disease-Gene Associations with annotated Relationships among genes. PMID:28812536
Genome-wide expression differences in anti-Vegf and dexamethasone treatment of inflammatory angiogenesis in the rat cornea. PMID:28811496
Inhibitors of the Histone Methyltransferases EZH2/1 Induce a Potent Antiviral State and Suppress Infection by Diverse Viral Pathogens. PMID:28811345
Identification of key genes and pathways associated with obesity in children. PMID:28810559
Genome-wide expression datasets of anti-VEGF and dexamethasone treatment of angiogenesis in the rat cornea. PMID:28809847
Discovery of Variants Underlying Host Susceptibility to Virus Infection Using Whole-Exome Sequencing. PMID:28808973
Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. PMID:28808245
Knowledge-guided gene prioritization reveals new insights into the mechanisms of chemoresistance. PMID:28800781
Whole exome sequencing as a diagnostic tool for patients with ciliopathy-like phenotypes. PMID:28800606
Identification of competing endogenous RNAs of the tumor suppressor gene PTEN: A probabilistic approach. PMID:28798471
mTOR regulates metabolic adaptation of APCs in the lung and controls the outcome of allergic inflammation. PMID:28798047
Functional prediction of miR-3144-5p in human cardiac myocytes based on transcriptome sequencing and bioinformatics. PMID:28796037
Identification of the anticancer effects of a novel proteasome inhibitor, ixazomib, on colorectal cancer using a combined method of microarray and bioinformatics analysis. PMID:28790851
Consensus strategy in genes prioritization and combined bioinformatics analysis for preeclampsia pathogenesis. PMID:28789679
The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. PMID:28787591
Bioenergetic Failure in Rat Oligodendrocyte Progenitor Cells Treated with Cerebrospinal Fluid Derived from Multiple Sclerosis Patients. PMID:28775680
The Image Data Resource: A Bioimage Data Integration and Publication Platform. PMID:28775673
UBE2O remodels the proteome during terminal erythroid differentiation. PMID:28774900
Construction and Optimization of a Large Gene Coexpression Network in Maize Using RNA-Seq Data. PMID:28768814
HIT'nDRIVE: patient-specific multidriver gene prioritization for precision oncology. PMID:28768687
Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages. PMID:28768414
Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications. PMID:28768201
RNA Polymerase Tags To Monitor Multidimensional Protein-Protein Interactions Reveal Pharmacological Engagement of Bcl-2 Proteins. PMID:28767232
Testis specific histone 2B is associated with sperm chromatin dynamics and bull fertility-a pilot study. PMID:28764714
Overlapping MicroRNA Expression in Saliva and Cerebrospinal Fluid Accurately Identifies Pediatric Traumatic Brain Injury. PMID:28762893
Reverse Nearest Neighbor Search on a Protein-Protein Interaction Network to Infer Protein-Disease Associations. PMID:28757797
Different Metabolic Pathways Are Involved in Response of Saccharomyces cerevisiae to L-A and M Viruses. PMID:28757599
Use of Microarray Datasets to generate Caco-2-dedicated Networks and to identify Reporter Genes of Specific Pathway Activity. PMID:28755007
Metabolome alterations in severe critical illness and vitamin D status. PMID:28750641
Proteomic analysis of human follicular fluid associated with successful in vitro fertilization. PMID:28750635
Prediction of novel target genes and pathways involved in irinotecan-resistant colorectal cancer. PMID:28749961
Acute coronary syndrome and acute kidney injury: role of inflammation in worsening renal function. PMID:28747177
Promising significance of the association of miR-204-5p expression with clinicopathological features of hepatocellular carcinoma. PMID:28746200
Oral squamous cell cancer protein-protein interaction network interpretation in comparison to esophageal adenocarcinoma. PMID:28744358
A comprehensive insight into the clinicopathologic significance of miR-144-3p in hepatocellular carcinoma. PMID:28744145
Pathogen recognition in compatible plant-microbe interactions. PMID:28743967
Decelerated neurodegeneration after intravitreal injection of α-synuclein antibodies in a glaucoma animal model. PMID:28740252
The helicase, DDX3X, interacts with poly(A)-binding protein 1 (PABP1) and caprin-1 at the leading edge of migrating fibroblasts and is required for efficient cell spreading. PMID:28733330
Proteomic profiling of early degenerative retina of RCS rats. PMID:28730077
Quantitative Assessment of the Effects of Trypsin Digestion Methods on Affinity Purification-Mass Spectrometry-based Protein-Protein Interaction Analysis. PMID:28726418
Impact of Proestrus on Gene Expression in the Medial Preoptic Area of Mice. PMID:28725181
Genetic risk between the CACNA1I gene and schizophrenia in Chinese Uygur population. PMID:28725167
Benchmarking selected computational gene network growing tools in context of virus-host interactions. PMID:28724991
Enhanced differential expression statistics for data-independent acquisition proteomics. PMID:28724900
RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells. PMID:28719611
CLIC, a tool for expanding biological pathways based on co-expression across thousands of datasets. PMID:28719601
SRF modulates seizure occurrence, activity induced gene transcription and hippocampal circuit reorganization in the mouse pilocarpine epilepsy model. PMID:28716058
Gene microarray analysis of expression profiles in liver ischemia and reperfusion. PMID:28713993
Exploration of the sequential gene changes in epithelial ovarian cancer induced by carboplatin via microarray analysis. PMID:28713952
CancerGD: A Resource for Identifying and Interpreting Genetic Dependencies in Cancer. PMID:28711281
Biological analysis of cancer specific microRNAs on function modeling in osteosarcoma. PMID:28710380
Transcriptome Analysis of Three Sheep Intestinal Regions reveals Key Pathways and Hub Regulatory Genes of Large Intestinal Lipid Metabolism. PMID:28706214
Feedback Microtubule Control and Microtubule-Actin Cross-talk in Arabidopsis Revealed by Integrative Proteomic and Cell Biology Analysis of KATANIN 1 Mutants. PMID:28706004
Elucidating Protein-DNA Interactions in Human Alphoid Chromatin via Hybridization Capture and Mass Spectrometry. PMID:28704058
Quantitative proteomics reveal the anti-tumour mechanism of the carbohydrate recognition domain of Galectin-3 in Hepatocellular carcinoma. PMID:28701735
Shikonin changes the lipopolysaccharide-induced expression of inflammation-related genes in macrophages. PMID:28699129
Transcriptome Sequencing Reveals Astrocytes as a Therapeutic Target in Heat-Stroke. PMID:28699024
Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching. PMID:28698546
Proteomic characterization of paired non-malignant and malignant African-American prostate epithelial cell lines distinguishes them by structural proteins. PMID:28697756
Metagenomic binning of a marine sponge microbiome reveals unity in defense but metabolic specialization. PMID:28696422
Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium. PMID:28694244
Development of an in silico method for the identification of subcomplexes involved in the biogenesis of multiprotein complexes in Saccharomyces cerevisiae. PMID:28693620
Prenatal Growth Patterns and Birthweight Are Associated With Differential DNA Methylation and Gene Expression of Cardiometabolic Risk Genes in Human Placentas: A Discovery-Based Approach. PMID:28693373
Identification of Pharmacologically Tractable Protein Complexes in Cancer Using the R-Based Network Clustering and Visualization Program MCODER. PMID:28691013
Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder. PMID:28688579
Strength of functional signature correlates with effect size in autism. PMID:28687074
Characterization of transcriptional modules related to fibrosing-NAFLD progression. PMID:28684781
Proteomic profiling of archaeological human bone. PMID:28680659
Pseudomonas aeruginosa cells attached to a surface display a typical proteome early as 20 minutes of incubation. PMID:28678862
Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase. PMID:28678185
Isoelectric point-based fractionation by HiRIEF coupled to LC-MS allows for in-depth quantitative analysis of the phosphoproteome. PMID:28674419
Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using SILAC-SPROX. PMID:28673085
Implication of the APP Gene in Intellectual Abilities. PMID:28671113
The Stress-Responding miR-132-3p Shows Evolutionarily Conserved Pathway Interactions. PMID:28667373
Oncogenic Protein Kinase D3 Regulating Networks in Invasive Breast Cancer. PMID:28656000
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation. PMID:28655759
A Quantitative Acetylomic Analysis of Early Seed Development in Rice (Oryza sativa L.). PMID:28654018
Functional annotation of Alzheimer's disease associated loci revealed by GWASs. PMID:28650998
Whole transcriptomic and proteomic analyses of an isogenic M. tuberculosis clinical strain with a naturally occurring 15 Kb genomic deletion. PMID:28650996
NetNorM: Capturing cancer-relevant information in somatic exome mutation data with gene networks for cancer stratification and prognosis. PMID:28650955
CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. PMID:28650476
Cross-species gene modules emerge from a systems biology approach to osteoarthritis. PMID:28649440
Meta-analysis of host response networks identifies a common core in tuberculosis. PMID:28649431
NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism. PMID:28648096
Proteome Profile of Aspergillus terreus Conidia at Germinating Stage: Identification of Probable Virulent Factors and Enzymes from Mycotoxin Pathways. PMID:28647921
Genome-wide analysis of DNA methylation in hypothalamus and ovary of Capra hircus. PMID:28645321
Characterizing the reproductive transcriptomic correlates of acute dehydration in males in the desert-adapted rodent, Peromyscus eremicus. PMID:28645248
Knockdown of Mtfp1 can minimize doxorubicin cardiotoxicity by inhibiting Dnm1l-mediated mitochondrial fission. PMID:28643438
Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos. PMID:28642470
Bacterial Cellulose Shifts Transcriptome and Proteome of Cultured Endothelial Cells Towards Native Differentiation. PMID:28637836
Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction. PMID:28634551
Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells. PMID:28634298
Regulation of cardiac myocyte cell death and differentiation by myocardin. PMID:28631251
Combined Mass Spectrometry Imaging and Top-down Microproteomics Reveals Evidence of a Hidden Proteome in Ovarian Cancer. PMID:28629911
BERing the burden of damage: Pathway crosstalk and posttranslational modification of base excision repair proteins regulate DNA damage management. PMID:28629773
A putative molecular network associated with colon cancer metastasis constructed from microarray data. PMID:28629469
Ubiquitin-Proteasome-Collagen (CUP) Pathway in Preterm Premature Rupture of Fetal Membranes. PMID:28626423
Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide. PMID:28625553
Alternative Polyadenylation Patterns for Novel Gene Discovery and Classification in Cancer. PMID:28624626
Prediction of lncRNA-protein interactions using HeteSim scores based on heterogeneous networks. PMID:28623317
Revealing protein networks and gene-drug connectivity in cancer from direct information. PMID:28623316
MyGeneFriends: A Social Network Linking Genes, Genetic Diseases, and Researchers. PMID:28623182
Functions of protein phosphatase-6 in NF-κB signaling and in lymphocytes. PMID:28620030
Antagonistic regulation of the second mitotic wave by Eyes absent-Sine oculis and Combgap coordinates proliferation and specification in the Drosophila retina. PMID:28619818
A TALE-inspired computational screen for proteins that contain approximate tandem repeats. PMID:28617832
Contextualization of drug-mediator relations using evidence networks. PMID:28617226
Genome-wide analyses of SWEET family proteins reveal involvement in fruit development and abiotic/biotic stress responses in banana. PMID:28615718
TCL1A Single-Nucleotide Polymorphisms and Estrogen-Mediated Toll-Like Receptor-MYD88-Dependent Nuclear Factor-κB Activation: Single-Nucleotide Polymorphism- and Selective Estrogen Receptor Modulator-Dependent Modification of Inflammation and Immune Response. PMID:28615284
Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach. PMID:28611792
Dammarane Sapogenins Ameliorates Neurocognitive Functional Impairment Induced by Simulated Long-Duration Spaceflight. PMID:28611667
Aberrant plasticity of peripheral sensory axons in a painful neuropathy. PMID:28611388
Inhibition of Avian Influenza A Virus Replication in Human Cells by Host Restriction Factor TUFM Is Correlated with Autophagy. PMID:28611246
Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas. PMID:28607076
Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Protein Vpr. PMID:28606917
Recent computational developments on CLIP-seq data analysis and microRNA targeting implications. PMID:28605404
A mutant O-GlcNAcase enriches Drosophila developmental regulators. PMID:28604694
Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies. PMID:28603644
An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes. PMID:28601559
Genome-wide survey of switchgrass NACs family provides new insights into motif and structure arrangements and reveals stress-related and tissue-specific NACs. PMID:28596552
mTFkb: a knowledgebase for fundamental annotation of mouse transcription factors. PMID:28596516
Precision medicine for hepatocelluar carcinoma using molecular pattern diagnostics: results from a preclinical pilot study. PMID:28594404
Identification of potential target genes associated with the effect of propranolol on angiosarcoma via microarray analysis. PMID:28588707
The Significant Pathways and Genes Underlying the Colon Cancer Treatment by the Traditional Chinese Medicine PHY906. PMID:28588641
Analysis of Microarray-Identified Genes and MicroRNAs Associated with Idiopathic Pulmonary Fibrosis. PMID:28588348
TCM-Mesh: The database and analytical system for network pharmacology analysis for TCM preparations. PMID:28588237
Characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling by integrative analysis of transcriptomic and proteomic data. PMID:28588230
The RNA helicase DHX9 establishes nucleolar heterochromatin, and this activity is required for embryonic stem cell differentiation. PMID:28588071
NaviSE: superenhancer navigator integrating epigenomics signal algebra. PMID:28587674
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases. PMID:28586827
The IDA-LIKE peptides IDL6 and IDL7 are negative modulators of stress responses in Arabidopsis thaliana. PMID:28586470
Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes. PMID:28585547
Data on the association of the nuclear envelope protein Sun1 with nucleoli. PMID:28580408
Leucine-rich glioma inactivated 3: integrative analyses support its prognostic role in glioma. PMID:28579810
Expression and integrated network analyses revealed functional divergence of NHX-type Na+/H+ exchanger genes in poplar. PMID:28572621
The Ser/Thr Protein Kinase Protein-Protein Interaction Map of M. tuberculosis. PMID:28572091
Comparative Genomic Analysis Reveals Habitat-Specific Genes and Regulatory Hubs within the Genus Novosphingobium. PMID:28567447
Identification of key genes and pathways for peri-implantitis through the analysis of gene expression data. PMID:28565775
Prediction of marker genes associated with hypertension by bioinformatics analyses. PMID:28560446
Revealing radiotherapy- and chemoradiation-induced pathway dynamics in glioblastoma by analyzing multiple differential networks. PMID:28560382
Global Transcriptome Analysis of Combined Abiotic Stress Signaling Genes Unravels Key Players in Oryza sativa L.: An In silico Approach. PMID:28555143
Early transcriptome responses of the bovine midcycle corpus luteum to prostaglandin F2α includes cytokine signaling. PMID:28549990
Disentangling Timing of Admixture, Patterns of Introgression, and Phenotypic Indicators in a Hybridizing Wolf Population. PMID:28549194
ChiPPI: a novel method for mapping chimeric protein-protein interactions uncovers selection principles of protein fusion events in cancer. PMID:28549153
Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis. PMID:28548640
Identification of transcription factors potentially involved in human adipogenesis in vitro. PMID:28546992
Genetic variation and expression levels of tight junction genes identifies association between MAGI3 and inflammatory bowel disease. PMID:28545409
Lack of the PGA exopolysaccharide in Salmonella as an adaptive trait for survival in the host. PMID:28542593
Biofilm microenvironment induces a widespread adaptive amino-acid fermentation pathway conferring strong fitness advantage in Escherichia coli. PMID:28542503
Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition. PMID:28537268
The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells. PMID:28536419
Circadian networks in human embryonic stem cell-derived cardiomyocytes. PMID:28536247
Proteomic Analysis of Chicken Skeletal Muscle during Embryonic Development. PMID:28533755
Proteomic analysis of JAK2V617F-induced changes identifies potential new combinatorial therapeutic approaches. PMID:28533538
Clinical Value and Prospective Pathway Signaling of MicroRNA-375 in Lung Adenocarcinoma: A Study Based on the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO) and Bioinformatics Analysis. PMID:28533502
Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases. PMID:28529637
Bioinformatics and in vitro experimental analyses identify the selective therapeutic potential of interferon gamma and apigenin against cervical squamous cell carcinoma and adenocarcinoma. PMID:28526810
Gene expression of Vibrio parahaemolyticus growing in laboratory isolation conditions compared to those common in its natural ocean environment. PMID:28525966
A computational framework for distinguishing direct versus indirect interactions in human functional protein-protein interaction networks. PMID:28524201
NFPscanner: a webtool for knowledge-based deciphering of biomedical networks. PMID:28521733
Host Plant Compatibility Shapes the Proteogenome of Frankia coriariae. PMID:28512450
Phosphoproteome Analysis Reveals Phosphorylation Underpinnings in the Brains of Nurse and Forager Honeybees (Apis mellifera). PMID:28512345
Histone Deacetylase Inhibitor SAHA Is a Promising Treatment of Cushing Disease. PMID:28505327
Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation. PMID:28504707
Transcriptomic and macroevolutionary evidence for phenotypic uncoupling between frog life history phases. PMID:28504275
Postzygotic single-nucleotide mosaicisms contribute to the etiology of autism spectrum disorder and autistic traits and the origin of mutations. PMID:28503910
Hippocampal Proteomic Analysis Reveals Distinct Pathway Deregulation Profiles at Early and Late Stages in a Rat Model of Alzheimer's-Like Amyloid Pathology. PMID:28502044
Establishment of a Strong Link Between Smoking and Cancer Pathogenesis through DNA Methylation Analysis. PMID:28500316
FcγRIIIa Signaling Modulates Endosomal TLR Responses in Human CD4+ T Cells. PMID:28500073
miR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin. PMID:28499703
Proteomics analysis of pleomorphic adenoma of the human parotid gland. PMID:28497265
Genomic biomarkers of prenatal intrauterine inflammation in umbilical cord tissue predict later life neurological outcomes. PMID:28493900
Large scale phosphoprotein profiling to explore Drosophila cold acclimation regulatory mechanisms. PMID:28490779
Nipple aspirate fluid-A liquid biopsy for diagnosing breast health. PMID:28488344
Identification of novel genes associated with fracture healing in osteoporosis induced by Krm2 overexpression or Lrp5 deficiency. PMID:28487939
Bioinformatics in translational drug discovery. PMID:28487472
Detecting the Molecular System Signatures of Idiopathic Pulmonary Fibrosis through Integrated Genomic Analysis. PMID:28484236
Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models. PMID:28481952
Unbiased Protein Association Study on the Public Human Proteome Reveals Biological Connections between Co-Occurring Protein Pairs. PMID:28480704
CDC42-related genes are upregulated in helper T cells from obese asthmatic children. PMID:28479334
Connective Tissue Growth Factor Promotes Efficient Generation of Human Induced Pluripotent Stem Cell-Derived Choroidal Endothelium. PMID:28474838
COFACTOR: improved protein function prediction by combining structure, sequence and protein-protein interaction information. PMID:28472402
Mitochondria-targeted antioxidants as highly effective antibiotics. PMID:28469140
Mass Spectrometric Analyses Reveal a Central Role for Ubiquitylation in Remodeling the Arabidopsis Proteome during Photomorphogenesis. PMID:28461270
Insights into Ciliary Genes and Evolution from Multi-Level Phylogenetic Profiling. PMID:28460059
Quantitative cardiac phosphoproteomics profiling during ischemia-reperfusion in an immature swine model. PMID:28455290
Investigation of differentially-expressed microRNAs and genes in cervical cancer using an integrated bioinformatics analysis. PMID:28454467
Linearity of network proximity measures: implications for set-based queries and significance testing. PMID:28453667
Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity. PMID:28449024
Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression. PMID:28447619
Proteomics Analysis of Tissue Samples Reveals Changes in Mitochondrial Protein Levels in Parathyroid Hyperplasia over Adenoma. PMID:28446534
Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy. PMID:28441737
A genomics approach identifies selective effects of trans-resveratrol in cerebral cortex neuron and glia gene expression. PMID:28441400
Understanding human thiol dioxygenase enzymes: structure to function, and biology to pathology. PMID:28439920
A Quantitative Proteomic Analysis of Brassinosteroid-induced Protein Phosphorylation in Rice (Oryza sativa L.). PMID:28439285
Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response. PMID:28437467
Human fetal heart specific coexpression network involves congenital heart disease/defect candidate genes. PMID:28436429
A qRT-PCR and Gene Functional Enrichment Study Focused on Downregulation of miR-141-3p in Hepatocellular Carcinoma and Its Clinicopathological Significance. PMID:28436261
Proteomic analysis of mitochondrial proteins in the guinea pig heart following long-term normobaric hyperoxia. PMID:28432557
Network-aided Bi-Clustering for discovering cancer subtypes. PMID:28432308
Membrane-enriched proteome changes and prion protein expression during neural differentiation and in neuroblastoma cells. PMID:28431525
Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis. PMID:28431522
Identifying new susceptibility genes on dopaminergic and serotonergic pathways for the framing effect in decision-making. PMID:28431168
A large-scale benchmark of gene prioritization methods. PMID:28429739
Expression Profiling Coupled with In-silico Mapping Identifies Candidate Genes for Reducing Aflatoxin Accumulation in Maize. PMID:28428796
Mapping the Synthetic Dosage Lethality Network of CDK1/CDC28. PMID:28428242
Cross-disorder comparative analysis of comorbid conditions reveals novel autism candidate genes. PMID:28427329
Global analysis of protein lysine succinylation profiles in common wheat. PMID:28427325
Transcriptome of interstitial cells of Cajal reveals unique and selective gene signatures. PMID:28426719
Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer. PMID:28423713
Metabolism-related microRNAs in maternal breast milk are influenced by premature delivery. PMID:28422941
The clinical value, regulatory mechanisms, and gene network of the cancer-testis gene STK31 in pancreatic cancer. PMID:28422722
Outlining Core Pathways of Amyloid Toxicity in Bacteria with the RepA-WH1 Prionoid. PMID:28421043
Identification of driver modules in pan-cancer via coordinating coverage and exclusivity. PMID:28415609
Regulatory network of GATA3 in pediatric acute lymphoblastic leukemia. PMID:28415601
Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American. PMID:28413702
Identification of miRNA biomarkers of pneumonia using RNA-sequencing and bioinformatics analysis. PMID:28413462
Highly accessible AU-rich regions in 3' untranslated regions are hotspots for binding of regulatory factors. PMID:28410363
Dynamics of the Interaction between Cotton Bollworm Helicoverpa armigera and Nucleopolyhedrovirus as Revealed by Integrated Transcriptomic and Proteomic Analyses. PMID:28404795
Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. PMID:28397817
Bioinformatics analysis of gene expression alterations in microRNA‑122 knockout mice with hepatocellular carcinoma. PMID:28393247
Integrated network analysis reveals potentially novel molecular mechanisms and therapeutic targets of refractory epilepsies. PMID:28388656
A Proteomic Analysis of the Malignant Mesothelioma Secretome Using iTRAQ. PMID:28387650
Connecting myelin-related and synaptic dysfunction in schizophrenia with SNP-rich gene expression hubs. PMID:28382934
DisBind: A database of classified functional binding sites in disordered and structured regions of intrinsically disordered proteins. PMID:28381244
Comparative study of joint bioinformatics analysis of underlying potential of 'neurimmiR', miR-212-3P/miR-132-3P, being involved in epilepsy and its emerging role in human cancer. PMID:28380454
Effect of Metformin on Adult Hippocampal Neurogenesis: Comparison with Donepezil and Links to Cognition. PMID:28378260
The Influence of HIV on the Evolution of Mycobacterium tuberculosis. PMID:28369607
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. PMID:28369058
Proteomic signature of muscle fibre hyperplasia in response to faba bean intake in grass carp. PMID:28367976
Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis. PMID:28366453
VerSeDa: vertebrate secretome database. PMID:28365718
Polymorphisms of RAD51B are associated with rheumatoid arthritis and erosion in rheumatoid arthritis patients. PMID:28361912
Active module identification in intracellular networks using a memetic algorithm with a new binary decoding scheme. PMID:28361692
Combinatorial Ranking of Gene Sets to Predict Disease Relapse: The Retinoic Acid Pathway in Early Prostate Cancer. PMID:28361034
Identification of key pathways and genes influencing prognosis in bladder urothelial carcinoma. PMID:28356754
ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease. PMID:28351972
Codon-level co-occurrences of germline variants and somatic mutations in cancer are rare but often lead to incorrect variant annotation and underestimated impact prediction. PMID:28350864
Gene expression-based biomarkers for discriminating early and late stage of clear cell renal cancer. PMID:28349958
Proteomics and integrative omic approaches for understanding host-pathogen interactions and infectious diseases. PMID:28348067
Quantitative Proteomics and Immunohistochemistry Reveal Insights into Cellular and Molecular Processes in the Infarct Border Zone One Month after Myocardial Infarction. PMID:28347137
Derivation of Functional Human Astrocytes from Cerebral Organoids. PMID:28345587
RNA-Seq transcriptomics and pathway analyses reveal potential regulatory genes and molecular mechanisms in high- and low-residual feed intake in Nordic dairy cattle. PMID:28340555
In silico search for modifier genes associated with pancreatic and liver disease in Cystic Fibrosis. PMID:28339466
Cross-Species Genome-Wide Identification of Evolutionary Conserved MicroProteins. PMID:28338802
Bivariate genomic analysis identifies a hidden locus associated with bacteria hypersensitive response in Arabidopsis thaliana. PMID:28338080
Computational modeling of in vivo and in vitro protein-DNA interactions by multiple instance learning. PMID:28334224
Data on interleukin (IL)-2- and IL-15-dependent changes in IL-2Rβ and IL-2Rγ complexes. PMID:28331895
Effects of insulin and the glucagon-like peptide 1 receptor agonist liraglutide on the kidney proteome in db/db mice. PMID:28330952
Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver. PMID:28329008
Mapping the N-linked glycosites of rice (Oryza sativa L.) germinating embryos. PMID:28328971
Identification of an RNase that preferentially cleaves A/G nucleotides. PMID:28322335
The effect of maternal chromium status on lipid metabolism in female elderly mice offspring and involved molecular mechanism. PMID:28320771
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions. PMID:28319085
Identification of Hip BMD Loss and Fracture Risk Markers Through Population-Based Serum Proteomics. PMID:28316103
Transcriptomic Analyses Elucidate Adaptive Differences of Closely Related Strains of Pseudomonas aeruginosa in Fuel. PMID:28314727
Vector Integration Sites Identification for Gene-Trap Screening in Mammalian Haploid Cells. PMID:28303933
Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis. PMID:28302149
Genome-wide identification, classification, and functional analysis of the basic helix-loop-helix transcription factors in the cattle, Bos Taurus. PMID:28299435
Integrating functional genomics to accelerate mechanistic personalized medicine. PMID:28299357
Bacterial protein meta-interactomes predict cross-species interactions and protein function. PMID:28298180
Genome-wide identification and characterization of small RNAs in Rhodobacter capsulatus and identification of small RNAs affected by loss of the response regulator CtrA. PMID:28296577
Comprehensive proteome analysis of human skeletal muscle in cachexia and sarcopenia: a pilot study. PMID:28296247
A bacterial aromatic aldehyde dehydrogenase critical for the efficient catabolism of syringaldehyde. PMID:28294121
Low circulating microRNA levels in heart failure patients are associated with atherosclerotic disease and cardiovascular-related rehospitalizations. PMID:28293796
SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling. PMID:28292441
Microarray technology reveals potentially novel genes and pathways involved in non-functioning pituitary adenomas. PMID:28289583
Enlightening discriminative network functional modules behind Principal Component Analysis separation in differential-omic science studies. PMID:28287094
Meta-Analysis of Gene Expression Profiles in Acute Promyelocytic Leukemia Reveals Involved Pathways. PMID:28286608
Proteome-Scale Human Interactomics. PMID:28284537
Understanding Host-Pathogen Interactions with Expression Profiling of NILs Carrying Rice-Blast Resistance Pi9 Gene. PMID:28280498
NV Proteins of Fish Novirhabdovirus Recruit Cellular PPM1Bb Protein Phosphatase and Antagonize RIG-I-Mediated IFN Induction. PMID:28276468
Principal Components Analysis Based Unsupervised Feature Extraction Applied to Gene Expression Analysis of Blood from Dengue Haemorrhagic Fever Patients. PMID:28276456
Chronically dysregulated NOTCH1 interactome in the dentate gyrus after traumatic brain injury. PMID:28273100
Global protein expression profile response of planktonic Aeromonas hydrophila exposed to chlortetracycline. PMID:28271383
Network Reconstruction Reveals that Valproic Acid Activates Neurogenic Transcriptional Programs in Adult Brain Following Traumatic Injury. PMID:28271248
Protein profiles of hatchery egg shell membrane. PMID:28270742
Identifying protein kinase-specific effectors of the osmostress response in yeast. PMID:28270554
Social network architecture of human immune cells unveiled by quantitative proteomics. PMID:28263321
A temporal proteome dynamics study reveals the molecular basis of induced phenotypic resistance in Mycobacterium smegmatis at sub-lethal rifampicin concentrations. PMID:28262820
Characterization of gene expression profiles in HBV-related liver fibrosis patients and identification of ITGBL1 as a key regulator of fibrogenesis. PMID:28262670
Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder. PMID:28261056
Screening of potential gene markers for predicting carotid atheroma plaque formation using bioinformatics approaches. PMID:28260035
Avoiding the pitfalls of gene set enrichment analysis with SetRank. PMID:28259142
Identifying and Analyzing Novel Epilepsy-Related Genes Using Random Walk with Restart Algorithm. PMID:28255556
Serum Proteome Alterations in Patients with Cognitive Impairment after Traumatic Brain Injury Revealed by iTRAQ-Based Quantitative Proteomics. PMID:28251161
Advances in mass spectrometry based strategies to study receptor tyrosine kinases. PMID:28250950
A Staphylococcus aureus Proteome Overview: Shared and Specific Proteins and Protein Complexes from Representative Strains of All Three Clades. PMID:28248218
Decreased Tissue COX5B Expression and Mitochondrial Dysfunction during Sepsis-Induced Kidney Injury in Rats. PMID:28246552
Label-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line. PMID:28242843
Insights into the molecular mechanisms of Polygonum multiflorum Thunb-induced liver injury: a computational systems toxicology approach. PMID:28239160
OAS Gene Family Expression Is Associated with HIV-Related Neurocognitive Disorders. PMID:28236279
Genome Wide In silico Analysis of the Mismatch Repair Components of Plasmodium falciparum and Their Comparison with Human Host. PMID:28232818
Investigating ego modules and pathways in osteosarcoma by integrating the EgoNet algorithm and pathway analysis. PMID:28225867
Coordination of Myeloid Differentiation with Reduced Cell Cycle Progression by PU.1 Induction of MicroRNAs Targeting Cell Cycle Regulators and Lipid Anabolism. PMID:28223367
Direct experimental manipulation of intestinal cells in Ascaris suum, with minor influences on the global transcriptome. PMID:28223178
Premature primary tooth eruption in cognitive/motor-delayed ADNP-mutated children. PMID:28221363
Integrated Regulatory and Metabolic Networks of the Marine Diatom Phaeodactylum tricornutum Predict the Response to Rising CO2 Levels. PMID:28217746
Transcriptomic dynamics of breast cancer progression in the MMTV-PyMT mouse model. PMID:28212608
Proteomic Analysis of Postsynaptic Protein Complexes Underlying Neuronal Plasticity. PMID:28211672
Differential signaling through p190 and p210 BCR-ABL fusion proteins revealed by interactome and phosphoproteome analysis. PMID:28210003
RNA-Seq-based transcriptomic and metabolomic analysis reveal stress responses and programmed cell death induced by acetic acid in Saccharomyces cerevisiae. PMID:28209995
Generation and quantitative proteomics analysis of CK2α/α'(-/-) cells. PMID:28209983
Immunoinformatics Features Linked to Leishmania Vaccine Development: Data Integration of Experimental and In Silico Studies. PMID:28208616
FocusHeuristics - expression-data-driven network optimization and disease gene prediction. PMID:28205611
The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. PMID:28205554
Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning. PMID:28200013
Predicting disease-related genes using integrated biomedical networks. PMID:28198675
Global Characterization of Protein Secretion from Human Macrophages Following Non-canonical Caspase-4/5 Inflammasome Activation. PMID:28196878
Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays. PMID:28196595
Polyfunctional and IFN-γ monofunctional human CD4+ T cell populations are molecularly distinct. PMID:28194431
Computational identification of the selenocysteine tRNA (tRNASec) in genomes. PMID:28192430
Time-resolved Phosphoproteome Analysis of Paradoxical RAF Activation Reveals Novel Targets of ERK. PMID:28188228
Adaptive and Behavioral Changes in Kynurenine 3-Monooxygenase Knockout Mice: Relevance to Psychotic Disorders. PMID:28187857
A novel integrative risk index of papillary thyroid cancer progression combining genomic alterations and clinical factors. PMID:28187428
Proteomic Screen for Cellular Targets of the Vaccinia Virus F10 Protein Kinase Reveals that Phosphorylation of mDia Regulates Stress Fiber Formation. PMID:28183815
Meta-analysis of gene expression in relapsed childhood B-acute lymphoblastic leukemia. PMID:28183295
An integrative study on the impact of highly differentially methylated genes on expression and cancer etiology. PMID:28178311
CPSS 2.0: a computational platform update for the analysis of small RNA sequencing data. PMID:28177064
Differential Regulation of Cryptic Genetic Variation Shapes the Genetic Interactome Underlying Complex Traits. PMID:28172852
Analysis of small RNAs revealed differential expressions during pollen and embryo sac development in autotetraploid rice. PMID:28166742
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. PMID:28166213
Therapeutic effects of Euphorbia Pekinensis and Glycyrrhiza glabra on Hepatocellular Carcinoma Ascites Partially Via Regulating the Frk-Arhgdib-Inpp5d-Avpr2-Aqp4 Signal Axis. PMID:28165501
Insights into Diabetic Kidney Disease Using Urinary Proteomics and Bioinformatics. PMID:28159781
Bridging Chromosomal Architecture and Pathophysiology of Streptococcus pneumoniae. PMID:28158485
Integrative analysis of methylation and transcriptional profiles to predict aging and construct aging specific cross-tissue networks. PMID:28155676
Genome-wide analysis of mRNAs associated with mouse peroxisomes. PMID:28155669
BicPAMS: software for biological data analysis with pattern-based biclustering. PMID:28153040
Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer. PMID:28152595
Identification of calgranulin B interacting proteins and network analysis in gastrointestinal cancer cells. PMID:28152021
Genome composition and phylogeny of microbes predict their co-occurrence in the environment. PMID:28152007
Mapping Biological Networks from Quantitative Data-Independent Acquisition Mass Spectrometry: Data to Knowledge Pipelines. PMID:28150249
Protein Bioinformatics Databases and Resources. PMID:28150231
An interactomics overview of the human and bovine milk proteome over lactation. PMID:28149201
Predictive characterization of hypothetical proteins in Staphylococcus aureus NCTC 8325. PMID:28149057
Insights using the molecular model of Lipoxygenase from Finger millet (Eleusine coracana (L.)). PMID:28149050
The Transcription Profile Unveils the Cardioprotective Effect of Aspalathin against Lipid Toxicity in an In Vitro H9c2 Model. PMID:28146135
Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. PMID:28131822
A Systematic Framework for Drug Repositioning from Integrated Omics and Drug Phenotype Profiles Using Pathway-Drug Network. PMID:28127549
Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion. PMID:28123935
Identifying key stage-specific genes and transcription factors for gastric cancer based on RNA-sequencing data. PMID:28121923
Identifying key genes associated with Hirschsprung's disease based on bioinformatics analysis of RNA-sequencing data. PMID:28120235
Quantitative iTRAQ Proteomics Revealed Possible Roles for Antioxidant Proteins in Sorghum Aluminum Tolerance. PMID:28119720
GSAR: Bioconductor package for Gene Set analysis in R. PMID:28118818
Genome-Wide Association between Transcription Factor Expression and Chromatin Accessibility Reveals Regulators of Chromatin Accessibility. PMID:28118358
The aliphatic amidase AmiE is involved in regulation of Pseudomonas aeruginosa virulence. PMID:28117457
Distribution and differential expression of microRNAs in the intestinal mucosal layer of necrotic enteritis induced Fayoumi chickens. PMID:28111433
Associations between hepatic miRNA expression, liver triacylglycerols and gut microbiota during metabolic adaptation to high-fat diet in mice. PMID:28105518
Urinary Extracellular Vesicles: Potential Biomarkers of Renal Function in Diabetic Patients. PMID:28105442
A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation. PMID:28098257
Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurification. PMID:28098164
Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures. PMID:28097054
Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome. PMID:28096346
Differential Effects of Vitamins A and D on the Transcriptional Landscape of Human Monocytes during Infection. PMID:28094291
Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition. PMID:28093501
Centrality in the host-pathogen interactome is associated with pathogen fitness during infection. PMID:28090086
Whole-Genome DNA Methylation Profiling Identifies Epigenetic Signatures of Uterine Carcinosarcoma. PMID:28088687
Invasion of Host Cells and Tissues by Uropathogenic Bacteria. PMID:28087946
A Human Proteome Array Approach to Identifying Key Host Proteins Targeted by Toxoplasma Kinase ROP18. PMID:28087594
Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors. PMID:28087593
RNAi reveals proteins for metabolism and protein processing associated with Langat virus infection in Ixodes scapularis (black-legged tick) ISE6 cells. PMID:28086865
Cross-talk between lipid and protein carbonylation in a dynamic cardiomyocyte model of mild nitroxidative stress. PMID:28086193
Testicular Dysgenesis Syndrome and Long-Lasting Epigenetic Silencing of Mouse Sperm Genes Involved in the Reproductive System after Prenatal Exposure to DEHP. PMID:28085963
Genome-Wide Transcriptional and Post-transcriptional Regulation of Innate Immune and Defense Responses of Bovine Mammary Gland to Staphylococcus aureus. PMID:28083515
Comparative Genomics of H. pylori and Non-Pylori Helicobacter Species to Identify New Regions Associated with Its Pathogenicity and Adaptability. PMID:28078297
Saffron'omics': The challenges of integrating omic technologies. PMID:28078242
Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity. PMID:28077577
RAIN: RNA-protein Association and Interaction Networks. PMID:28077569
Systemically identifying and prioritizing risk lncRNAs through integration of pan-cancer phenotype associations. PMID:28076842
Integrated analysis of differentially expressed genes and pathways in triple‑negative breast cancer. PMID:28075450
A Network Pharmacology Approach to Explore the Pharmacological Mechanism of Xiaoyao Powder on Anovulatory Infertility. PMID:28074099
A Survey of Computational Tools to Analyze and Interpret Whole Exome Sequencing Data. PMID:28070503
Identification and Characterization of MicroRNA Differentially Expressed in Macrophages Exposed to Porphyromonas gingivalis Infection. PMID:28069815
Annexin/S100A Protein Family Regulation through p14ARF-p53 Activation: A Role in Cell Survival and Predicting Treatment Outcomes in Breast Cancer. PMID:28068434
Unbiased Identification of Blood-based Biomarkers for Pulmonary Tuberculosis by Modeling and Mining Molecular Interaction Networks. PMID:28065665
A proteomic approach to identify endosomal cargoes controlling cancer invasiveness. PMID:28062852
Integrated Cellular and Plasma Proteomics of Contrasting B-cell Cancers Reveals Common, Unique and Systemic Signatures. PMID:28062796
Proteomic characterization of microdissected breast tissue environment provides a protein-level overview of malignant transformation. PMID:28058811
Molecular Characterization of N-glycan Degradation and Transport in Streptococcus pneumoniae and Its Contribution to Virulence. PMID:28056108
Gene length as a biological timer to establish temporal transcriptional regulation. PMID:28055303
Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases. PMID:28053689
The 24th annual Nucleic Acids Research database issue: a look back and upcoming changes. PMID:28053160
A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis. PMID:28041642
Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116. PMID:28036279
Neuroblastoma, a Paradigm for Big Data Science in Pediatric Oncology. PMID:28035989
Identified molecular mechanism of interaction between environmental risk factors and differential expression genes in cartilage of Kashin-Beck disease. PMID:28033256
Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip. PMID:28031399
Rare CNVs in Suicide Attempt include Schizophrenia-Associated Loci and Neurodevelopmental Genes: A Pilot Genome-Wide and Family-Based Study. PMID:28030616
iTRAQ-Based Proteomics Identification of Serum Biomarkers of Two Chronic Hepatitis B Subtypes Diagnosed by Traditional Chinese Medicine. PMID:28025641
Molecular and Proteomic Analysis of Levofloxacin and Metronidazole Resistant Helicobacter pylori. PMID:28018334
GPS-PAIL: prediction of lysine acetyltransferase-specific modification sites from protein sequences. PMID:28004786
Deep sequencing of wheat sRNA transcriptome reveals distinct temporal expression pattern of miRNAs in response to heat, light and UV. PMID:28004741
Association of CCND1 Gene c.870G>A Polymorphism with Breast Cancer Risk: A Case-ControlStudy and a Meta-Analysis. PMID:28004353
Semaphorin 4C: A Novel Component of B-Cell Polarization in Th2-Driven Immune Responses. PMID:28003812
Investigation of the Effects and Mechanisms of Mai Tong Formula on Lower Limb Macroangiopathy in a Spontaneous Diabetic Rat Model. PMID:27995148
Cytological behaviour of floral organs and in silico characterization of differentially expressed transcript-derived fragments associated with 'floral bud distortion' in soybean. PMID:27994177
An integrated multi-omics analysis of the NK603 Roundup-tolerant GM maize reveals metabolism disturbances caused by the transformation process. PMID:27991589
Characterization of glomerular extracellular matrix by proteomic analysis of laser-captured microdissected glomeruli. PMID:27988214
A novel independence test for somatic alterations in cancer shows that biology drives mutual exclusivity but chance explains most co-occurrence. PMID:27986087
The BioGRID interaction database: 2017 update. PMID:27980099
Investigating the human Calcineurin Interaction Network using the πɸLxVP SLiM. PMID:27974827
Bottom-up proteomics analysis of the secretome of murine islets of Langerhans in elevated glucose levels. PMID:27966681
XGR software for enhanced interpretation of genomic summary data, illustrated by application to immunological traits. PMID:27964755
Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery. PMID:27955713
Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease. PMID:27942582
Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat. PMID:27933490
Revisiting Vitis vinifera Subtilase Gene Family: A Possible Role in Grapevine Resistance against Plasmopara viticola. PMID:27933087
Cannabidiol Modulates the Immunophenotype and Inhibits the Activation of the Inflammasome in Human Gingival Mesenchymal Stem Cells. PMID:27932991
Reprogramming cell fate with a genome-scale library of artificial transcription factors. PMID:27930301
Proteomic profile of maternal-aged blastocoel fluid suggests a novel role for ubiquitin system in blastocyst quality. PMID:27924460
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible. PMID:27924014
Norspermidine changes the basic structure of S. mutans biofilm. PMID:27922663
A Molecular Basis for the Presentation of Phosphorylated Peptides by HLA-B Antigens. PMID:27920218
A Network Approach of Gene Co-expression in the Zea mays/Aspergillus flavus Pathosystem to Map Host/Pathogen Interaction Pathways. PMID:27917194
p53 Specifically Binds Triplex DNA In Vitro and in Cells. PMID:27907175
Global Deletion of TSPO Does Not Affect the Viability and Gene Expression Profile. PMID:27907096
Phylogenetic analysis of basic helix-loop-helix transcription factors in the genome of a typical human-disease vector. PMID:27904685
Joint Profiling of miRNAs and mRNAs Reveals miRNA Mediated Gene Regulation in the Göttingen Minipig Obesity Model. PMID:27902747
AtPID: a genome-scale resource for genotype-phenotype associations in Arabidopsis. PMID:27899679
The SWISS-MODEL Repository-new features and functionality. PMID:27899672
RAID v2.0: an updated resource of RNA-associated interactions across organisms. PMID:27899615
XTalkDB: a database of signaling pathway crosstalk. PMID:27899583
DIFFERENTIAL PATHWAY DEPENDENCY DISCOVERY ASSOCIATED WITH DRUG RESPONSE ACROSS CANCER CELL LINES. PMID:27897001
DISCOVERY OF FUNCTIONAL AND DISEASE PATHWAYS BY COMMUNITY DETECTION IN PROTEIN-PROTEIN INTERACTION NETWORKS. PMID:27896987
PROSNET: INTEGRATING HOMOLOGY WITH MOLECULAR NETWORKS FOR PROTEIN FUNCTION PREDICTION. PMID:27896959
A scored human protein-protein interaction network to catalyze genomic interpretation. PMID:27892958
RNA-Sequencing for profiling goat milk transcriptome in colostrum and mature milk. PMID:27884183
Highly expressed ribosomal protein L34 indicates poor prognosis in osteosarcoma and its knockdown suppresses osteosarcoma proliferation probably through translational control. PMID:27883047
Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences. PMID:27881428
RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy. PMID:27880896
Insights from the Cold Transcriptome and Metabolome of Dendrobium officinale: Global Reprogramming of Metabolic and Gene Regulation Networks during Cold Acclimation. PMID:27877182
Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer. PMID:27876705
Transcriptome-Based Analysis of Dof Family Transcription Factors and Their Responses to Abiotic Stress in Tea Plant (Camellia sinensis). PMID:27872842
Systems Biomedicine of Rabies Delineates the Affected Signaling Pathways. PMID:27872612
Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD. PMID:27871310
Advances on plant-pathogen interactions from molecular toward systems biology perspectives. PMID:27870294
Antizyme inhibitor 1: a potential carcinogenic molecule. PMID:27870265
Differentiated regulation of immune-response related genes between LUAD and LUSC subtypes of lung cancers. PMID:27863400
Nicotine-induced protein expression profiling reveals mutually altered proteins across four human cell lines. PMID:27862958
Tandem affinity purification of AtTERT reveals putative interaction partners of plant telomerase in vivo. PMID:27853871
Identification of potential genes for human ischemic cardiomyopathy based on RNA-Seq data. PMID:27852050
Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes. PMID:27845903
Proliferation rates and gene expression profiles in human lymphoblastoid cell lines from patients with depression characterized in response to antidepressant drug therapy. PMID:27845776
Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration. PMID:27845394
Transcriptome analysis of Arabidopsis mutants suggests a crosstalk between ABA, ethylene and GSH against combined cold and osmotic stress. PMID:27845361
Gene expression profile of whole blood cells differs in pregnant women with positive screening and negative diagnosis for gestational diabetes. PMID:27843554
Systemic Approach to Virulence Gene Network Analysis for Gaining New Insight into Cryptococcal Virulence. PMID:27833589
Novel RpoS-Dependent Mechanisms Strengthen the Envelope Permeability Barrier during Stationary Phase. PMID:27821607
Multi-label ℓ2-regularized logistic regression for predicting activation/inhibition relationships in human protein-protein interaction networks. PMID:27819359
Identification of microRNA profile specific to cancer stem-like cells directly isolated from human larynx cancer specimens. PMID:27816053
AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin. PMID:27813479
Characterization of a male reproductive transcriptome for Peromyscus eremicus (Cactus mouse). PMID:27812417
Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins. PMID:27812135
Daesiho-Tang Is an Effective Herbal Formulation in Attenuation of Obesity in Mice through Alteration of Gene Expression and Modulation of Intestinal Microbiota. PMID:27812119
A combination of genome-wide association and transcriptome analysis reveals candidate genes controlling harvest index-related traits in Brassica napus. PMID:27811979
AMMECR1: a single point mutation causes developmental delay, midface hypoplasia and elliptocytosis. PMID:27811305
Large-scale gene co-expression network as a source of functional annotation for cattle genes. PMID:27806696
High NUCB2 expression level represents an independent negative prognostic factor in Chinese cohorts of non-metastatic clear cell renal cell carcinoma patients. PMID:27806328
Large-scale identification of adverse drug reaction-related proteins through a random walk model. PMID:27805066
Genetic-and-Epigenetic Interspecies Networks for Cross-Talk Mechanisms in Human Macrophages and Dendritic Cells during MTB Infection. PMID:27803888
Dysregulation of mitotic machinery genes precedes genome instability during spontaneous pre-malignant transformation of mouse ovarian surface epithelial cells. PMID:27801298
OGEE v2: an update of the online gene essentiality database with special focus on differentially essential genes in human cancer cell lines. PMID:27799467
Identification of novel genes and networks governing hematopoietic stem cell development. PMID:27797851
In-Depth Proteomic Analysis of the Porcine Retina by Use of a four Step Differential Extraction Bottom up LC MS Platform. PMID:27796761
HIPPIE v2.0: enhancing meaningfulness and reliability of protein-protein interaction networks. PMID:27794551
iTRAQ-Based Quantitative Proteomic Analysis of the Potentiated and Dormant Antler Stem Cells. PMID:27792145
Metformin treatment reduces temozolomide resistance of glioblastoma cells. PMID:27791206
Gene Expression Dynamics Accompanying the Sponge Thermal Stress Response. PMID:27788197
Maternal Chromium Restriction Leads to Glucose Metabolism Imbalance in Mice Offspring through Insulin Signaling and Wnt Signaling Pathways. PMID:27782077
Quantitative proteomics reveals Piccolo as a candidate serological correlate of recovery from Guillain-Barré syndrome. PMID:27776345
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. PMID:27775709
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways. PMID:27774996
Protein folding, binding, and droplet formation in cell-like conditions. PMID:27771543
Incorporating topological information for predicting robust cancer subnetwork markers in human protein-protein interaction network. PMID:27766944
Widespread occurrence of lysine methylation in Plasmodium falciparum proteins at asexual blood stages. PMID:27762281
Insulin stimulated MCF7 breast cancer cells: Proteome dataset. PMID:27761513
Identification of a regulation network in response to cadmium toxicity using blood clam Tegillarca granosa as model. PMID:27760991
Molecular Differences in Hepatic Metabolism between AA Broiler and Big Bone Chickens: A Proteomic Study. PMID:27760160
Identification of candidate biomarkers and analysis of prognostic values in ovarian cancer by integrated bioinformatics analysis. PMID:27757782
Transcriptome profiling of equine vitamin E deficient neuroaxonal dystrophy identifies upregulation of liver X receptor target genes. PMID:27751910
Dinitrogenase-Driven Photobiological Hydrogen Production Combats Oxidative Stress in Cyanothece sp. Strain ATCC 51142. PMID:27742679
Functionally distinct roles for different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukaemia. PMID:27740637
Network diffusion-based analysis of high-throughput data for the detection of differentially enriched modules. PMID:27731320
Infection with Plasmodium berghei ookinetes alters protein expression in the brain of Anopheles albimanus mosquitoes. PMID:27724938
Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants. PMID:27723757
Proteomic analysis of the signaling pathway mediated by the heterotrimeric Gα protein Pga1 of Penicillium chrysogenum. PMID:27716202
Iron homeostasis in Arabidopsis thaliana: transcriptomic analyses reveal novel FIT-regulated genes, iron deficiency marker genes and functional gene networks. PMID:27716045
Meta-analysis of gene expression and integrin-associated signaling pathways in papillary renal cell carcinoma subtypes. PMID:27705936
Network analysis of mitonuclear GWAS reveals functional networks and tissue expression profiles of disease-associated genes. PMID:27704213
Dissection of brassinosteroid-regulated proteins in rice embryos during germination by quantitative proteomics. PMID:27703189
MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis. PMID:27698367
Functional Metabolomics Describes the Yeast Biosynthetic Regulome. PMID:27693354
Chromosomal rearrangements and protein globularity changes in Mycobacterium tuberculosis isolates from cerebrospinal fluid. PMID:27688977
The emerging role of lysine methyltransferase SETD8 in human diseases. PMID:27688818
Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue. PMID:27686526
Prediction and validation of protein-protein interactors from genome-wide DNA-binding data using a knowledge-based machine-learning approach. PMID:27683156
Genome-wide associations for birth weight and correlations with adult disease. PMID:27680694
A systems biology approach to defining regulatory mechanisms for cartilage and tendon cell phenotypes. PMID:27670352
Transcriptional profile of SH-SY5Y human neuroblastoma cells transfected by Toxoplasma rhoptry protein 16. PMID:27666388
Finding lost genes in GWAS via integrative-omics analysis reveals novel sub-networks associated with preterm birth. PMID:27664809
A novel method for crosstalk analysis of biological networks: improving accuracy of pathway annotation. PMID:27664219
Transcriptome Profiling of the Pineapple under Low Temperature to Facilitate Its Breeding for Cold Tolerance. PMID:27656892
Somatic polyploidy is associated with the upregulation of c-MYC interacting genes and EMT-like signature. PMID:27655693
modPDZpep: a web resource for structure based analysis of human PDZ-mediated interaction networks. PMID:27655048
BiC2PAM: constraint-guided biclustering for biological data analysis with domain knowledge. PMID:27651825
Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein. PMID:27649274
DMAK: A curated pan-cancer DNA methylation annotation knowledgebase. PMID:27645405
Transcriptome Analysis Identifies the Dysregulation of Ultraviolet Target Genes in Human Skin Cancers. PMID:27643989
Evolutionary Analyses of Hanwoo (Korean Cattle)-Specific Single-Nucleotide Polymorphisms and Genes Using Whole-Genome Resequencing Data of a Hanwoo Population. PMID:27640093
Quantitative Proteomic Analysis of Wheat Seeds during Artificial Ageing and Priming Using the Isobaric Tandem Mass Tag Labeling. PMID:27632285
A Network-Based Data Integration Approach to Support Drug Repurposing and Multi-Target Therapies in Triple Negative Breast Cancer. PMID:27632168
Quercetin ameliorates Aβ toxicity in Drosophila AD model by modulating cell cycle-related protein expression. PMID:27626494
Biological Networks for Cancer Candidate Biomarkers Discovery. PMID:27625573
Language Impairments in ASD Resulting from a Failed Domestication of the Human Brain. PMID:27621700
Proteomic profiling of human islets collected from frozen pancreata using laser capture microdissection. PMID:27620696
Functional Annotations of Paralogs: A Blessing and a Curse. PMID:27618105
Investigating regulatory signatures of human autophagy related gene 5 (ATG5) through functional in silico analysis. PMID:27617225
Low-dose salinomycin induces anti-leukemic responses in AML and MLL. PMID:27612428
Comprehensive Proteome Profiling of Platelet Identified a Protein Profile Predictive of Responses to An Antiplatelet Agent Sarpogrelate. PMID:27601597
Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions. PMID:27598998
Complex Sources of Variation in Tissue Expression Data: Analysis of the GTEx Lung Transcriptome. PMID:27588449
Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages. PMID:27577261
The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing. PMID:27575636
Essential role of conserved DUF177A protein in plastid 23S rRNA accumulation and plant embryogenesis. PMID:27574185
Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target. PMID:27573516
A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment. PMID:27572311
Protein Co-Expression Analysis as a Strategy to Complement a Standard Quantitative Proteomics Approach: Case of a Glioblastoma Multiforme Study. PMID:27571357
Global profiling of alternative RNA splicing events provides insights into molecular differences between various types of hepatocellular carcinoma. PMID:27565572
Expression of non-secreted IL-4 is associated with HDAC inhibitor-induced cell death, histone acetylation and c-Jun regulation in human gamma/delta T-cells. PMID:27556516
Preliminary Validation of a High Docosahexaenoic Acid (DHA) and α-Linolenic Acid (ALA) Dietary Oil Blend: Tissue Fatty Acid Composition and Liver Proteome Response in Atlantic Salmon (Salmo salar) Smolts. PMID:27556399
Network analysis reveals potential markers for pediatric adrenocortical carcinoma. PMID:27555782
A single dividing cell population with imbalanced fate drives oesophageal tumour growth. PMID:27548914
PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain. PMID:27544407
A protein network descriptor server and its use in studying protein, disease, metabolic and drug targeted networks. PMID:27542402
Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension. PMID:27542232
The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells. PMID:27541004
Comprehensive Analysis of the Membrane Phosphoproteome Regulated by Oligogalacturonides in Arabidopsis thaliana. PMID:27532006
A single cell level measurement of StAR expression and activity in adrenal cells. PMID:27521960
Genomic Complexity Places Less Restrictions on the Evolution of Young Coexpression Networks than Protein-Protein Interactions. PMID:27521813
Libby amphibole-induced mesothelial cell autoantibodies bind to surface plasminogen and alter collagen matrix remodeling. PMID:27519611
Paralog-Specific Patterns of Structural Disorder and Phosphorylation in the Vertebrate SH3-SH2-Tyrosine Kinase Protein Family. PMID:27519537
Membranome: a database for proteome-wide analysis of single-pass membrane proteins. PMID:27510400
Modelling the Structure and Dynamics of Biological Pathways. PMID:27509052
Effects of Lipid-Lowering Drugs on Vancomycin Susceptibility of Mycobacteria. PMID:27503643
Databases and tools for constructing signal transduction networks in cancer. PMID:27502015
Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism. PMID:27496535
SoyNet: a database of co-functional networks for soybean Glycine max. PMID:27492285
MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c. PMID:27483380
Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing. PMID:27479907
Effects of Glucose and Starch on Lactate Production by Newly Isolated Streptococcus bovis S1 from Saanen Goats. PMID:27474714
Coordinated movement, neuromuscular synaptogenesis and trans-synaptic signaling defects in Drosophila galactosemia models. PMID:27466186
Assessment of Protein Binding of 5-Hydroxythalidomide Bioactivated in Humanized Mice with Human P450 3A-Chromosome or Hepatocytes by Two-Dimensional Electrophoresis/Accelerator Mass Spectrometry. PMID:27464947
Circadian Profiling of the Arabidopsis Proteome Using 2D-DIGE. PMID:27462335
Integrative proteomic analysis reveals reprograming tumor necrosis factor signaling in epithelial mesenchymal transition. PMID:27461979
Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS. PMID:27460707
Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells. PMID:27460362
Exome sequencing of Pakistani consanguineous families identifies 30 novel candidate genes for recessive intellectual disability. PMID:27457812
Genetic architecture dissection by genome-wide association analysis reveals avian eggshell ultrastructure traits. PMID:27456605
Spliceosome SNRNP200 Promotes Viral RNA Sensing and IRF3 Activation of Antiviral Response. PMID:27454487
Proteomics of hot-wet and cold-dry temperaments proposed in Iranian traditional medicine: a Network-based Study. PMID:27452083
Asparaginase-associated pancreatitis: a study on phenotype and genotype in the NOPHO ALL2008 protocol. PMID:27451978
Seven protective miRNA signatures for prognosis of cervical cancer. PMID:27447860
Genome-wide analyses of the bZIP family reveal their involvement in the development, ripening and abiotic stress response in banana. PMID:27445085
Machine Learning of Protein Interactions in Fungal Secretory Pathways. PMID:27441920
The cancer/testis-antigen PRAME supports the pluripotency network and represses somatic and germ cell differentiation programs in seminomas. PMID:27441500
Variation in PTCHD2, CRISP3, NAP1L4, FSCB, and AP3B2 associated with spherical equivalent. PMID:27440996
Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma. PMID:27439200
Identification of potential crucial gene network related to seasonal allergic rhinitis using microarray data. PMID:27435592
Systematic investigation of transcription factors critical in the protection against cerebral ischemia by Danhong injection. PMID:27431009
Glaucoma related Proteomic Alterations in Human Retina Samples. PMID:27425789
Systematic analysis of an evolved Thermobifida fusca muC producing malic acid on organic and inorganic nitrogen sources. PMID:27424527
Protein function in precision medicine: deep understanding with machine learning. PMID:27423136
Mastitomics, the integrated omics of bovine milk in an experimental model of Streptococcus uberis mastitis: 2. Label-free relative quantitative proteomics. PMID:27412694
Pleiotropic Genes Affecting Carcass Traits in Bos indicus (Nellore) Cattle Are Modulators of Growth. PMID:27410030
Metabolic Regulation as a Consequence of Anaerobic 5-Methylthioadenosine Recycling in Rhodospirillum rubrum. PMID:27406564
Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling Networks. PMID:27403431
The Pleiotropic Antibacterial Mechanisms of Ursolic Acid against Methicillin-Resistant Staphylococcus aureus (MRSA). PMID:27399657
Genome-wide association meta-analyses identified 1q43 and 2q32.2 for hip Ward's triangle areal bone mineral density. PMID:27397699
Identification of human serum protein targets of Qianggu Decoction () in primary type I osteoporosis based on tandem mass tag labeling and liquid chromatography-tandem mass spectrometry technology. PMID:27389089
RASopathies: Presentation at the Genome, Interactome, and Phenome Levels. PMID:27385963
HVint: A Strategy for Identifying Novel Protein-Protein Interactions in Herpes Simplex Virus Type 1. PMID:27384951
Thyroid hormone synthesis: a potential target of a Chinese herbal formula Haizao Yuhu Decoction acting on iodine-deficient goiter. PMID:27384475
Temperate phages both mediate and drive adaptive evolution in pathogen biofilms. PMID:27382184
JC Polyomavirus Infection of Primary Human Renal Epithelial Cells Is Controlled by a Type I IFN-Induced Response. PMID:27381292
Misannotation Awareness: A Tale of Two Gene-Groups. PMID:27379147
Identification of learning-induced changes in protein networks in the hippocampi of a mouse model of Alzheimer's disease. PMID:27378549
Comparative genomic analysis of novel Acinetobacter symbionts: A combined systems biology and genomics approach. PMID:27378055
Temporal Regulation of the Bacillus subtilis Acetylome and Evidence for a Role of MreB Acetylation in Cell Wall Growth. PMID:27376153
Principal component analysis based unsupervised feature extraction applied to budding yeast temporally periodic gene expression. PMID:27366210
Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways. PMID:27364358
Coordination of Metabolism and Virulence Factors Expression of Extraintestinal Pathogenic Escherichia coli Purified from Blood Cultures of Patients with Sepsis. PMID:27364158
Alpha-tubulin enhanced renal tubular cell proliferation and tissue repair but reduced cell death and cell-crystal adhesion. PMID:27363348
A Conserved MicroRNA Regulatory Circuit Is Differentially Controlled during Limb/Appendage Regeneration. PMID:27355827
Integration of Breast Cancer Secretomes with Clinical Data Elucidates Potential Serum Markers for Disease Detection, Diagnosis, and Prognosis. PMID:27355404
Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance. PMID:27345421
Endoplasmic reticulum stress and calcium imbalance are involved in cadmium-induced lipid aberrancy in Saccharomyces cerevisiae. PMID:27344570
Systematic identification and analysis of frequent gene fusion events in metabolic pathways. PMID:27342196
Reconstruction and Application of Protein-Protein Interaction Network. PMID:27338356
Transcriptome sequencing uncovers a three-long noncoding RNA signature in predicting breast cancer survival. PMID:27338266
Yeast two-hybrid screening identified WDR77 as a novel interacting partner of TSC22D2. PMID:27337956
Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies. PMID:27336693
QuIN: A Web Server for Querying and Visualizing Chromatin Interaction Networks. PMID:27336171
MUFFINN: cancer gene discovery via network analysis of somatic mutation data. PMID:27333808
An integrative imputation method based on multi-omics datasets. PMID:27329642
Overexpression of TELO2 decreases survival in human high-grade gliomas. PMID:27329594
Prognostic value and their clinical implication of 89-gene signature in glioma. PMID:27323413
Label-free Quantification of Proteins in Single Embryonic Cells with Neural Fate in the Cleavage-Stage Frog (Xenopus laevis) Embryo using Capillary Electrophoresis Electrospray Ionization High-Resolution Mass Spectrometry (CE-ESI-HRMS). PMID:27317400
GON4L Drives Cancer Growth through a YY1-Androgen Receptor-CD24 Axis. PMID:27312530
Filamentation of Metabolic Enzymes in Saccharomyces cerevisiae. PMID:27312010
Influence maximization in time bounded network identifies transcription factors regulating perturbed pathways. PMID:27307609
The genomic landscape of testicular germ cell tumours: from susceptibility to treatment. PMID:27296647
Donor age and long-term culture do not negatively influence the stem potential of limbal fibroblast-like stem cells. PMID:27296060
Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1. PMID:27286452
SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate. PMID:27283990
Integration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks. PMID:27280975
Molecular Portrait of Oral Tongue Squamous Cell Carcinoma Shown by Integrative Meta-Analysis of Expression Profiles with Validations. PMID:27280700
Cross-talk between AMPK and EGFR dependent Signaling in Non-Small Cell Lung Cancer. PMID:27279498
In-Utero Low-Dose Irradiation Leads to Persistent Alterations in the Mouse Heart Proteome. PMID:27276052
The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches. PMID:27264189
Dual Identification and Analysis of Differentially Expressed Transcripts of Porcine PK-15 Cells and Toxoplasma gondii during in vitro Infection. PMID:27242740
Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation. PMID:27242167
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria. PMID:27238023
Genomic and transcriptomic predictors of response levels to endurance exercise training. PMID:27234805
Cogena, a novel tool for co-expressed gene-set enrichment analysis, applied to drug repositioning and drug mode of action discovery. PMID:27234029
Axonal localization and mitochondrial association of precursor microRNA 338. PMID:27229124
Coevolution of RAC Small GTPases and their Regulators GEF Proteins. PMID:27226705
BicNET: Flexible module discovery in large-scale biological networks using biclustering. PMID:27213009
Chromatin Regulators as a Guide for Cancer Treatment Choice. PMID:27196757
Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism. PMID:27196572
The Unicellular Ancestry of Groucho-Mediated Repression and the Origins of Metazoan Transcription Factors. PMID:27189982
Regulatory Requirements for Staphylococcus aureus Nitric Oxide Resistance. PMID:27185828
Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis. PMID:27185526
Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9. PMID:27182943
Identification of novel direct targets of Drosophila Sine oculis and Eyes absent by integration of genome-wide data sets. PMID:27178668
Domestication-driven Gossypium profilin 1 (GhPRF1) gene transduces early flowering phenotype in tobacco by spatial alteration of apical/floral-meristem related gene expression. PMID:27177585
Learning from Heterogeneous Data Sources: An Application in Spatial Proteomics. PMID:27175778
Filtering large-scale event collections using a combination of supervised and unsupervised learning for event trigger classification. PMID:27175227
Extracting functional trends from whole genome duplication events using comparative genomics. PMID:27168732
Mining the human urine proteome for monitoring renal transplant injury. PMID:27165815
The PUF binding landscape in metazoan germ cells. PMID:27165521
Changes in Gene Expression and Estrogen Receptor Cistrome in Mouse Liver Upon Acute E2 Treatment. PMID:27164166
Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice. PMID:27163789
CNS repair and axon regeneration: Using genetic variation to determine mechanisms. PMID:27163547
NecroX-5 exerts anti-inflammatory and anti-fibrotic effects via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway in hypoxia/reoxygenation-treated rat hearts. PMID:27162485
Homeobox genes gain trimethylation of histone H3 lysine 4 in glioblastoma tissue. PMID:27160082
Laminin-binding integrin gene copy number alterations in distinct epithelial-type cancers. PMID:27158381
A New Approach for Identification of Cancer-related Pathways using Protein Networks and Genomic Data. PMID:27158220
Genome-scale prediction of moonlighting proteins using diverse protein association information. PMID:27153604
Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells. PMID:27153061
A Set of miRNAs, Their Gene and Protein Targets and Stromal Genes Distinguish Early from Late Onset ER Positive Breast Cancer. PMID:27152840
Molecular characterization of Gleason patterns 3 and 4 prostate cancer using reverse Warburg effect-associated genes. PMID:27152194
PathwAX: a web server for network crosstalk based pathway annotation. PMID:27151197
Data-based Reconstruction of Gene Regulatory Networks of Fungal Pathogens. PMID:27148247
Temporal Dysynchrony in brain connectivity gene expression following hypoxia. PMID:27146468
Multiple Differential Networks Strategy Reveals Carboplatin and Melphalan-Induced Dynamic Module Changes in Retinoblastoma. PMID:27144687
Physical activity delays hippocampal neurodegeneration and rescues memory deficits in an Alzheimer disease mouse model. PMID:27138799
Proteome Profile and Quantitative Proteomic Analysis of Buffalo (Bubalusbubalis) Follicular Fluid during Follicle Development. PMID:27136540
Phylogenetic Profiling for Probing the Modular Architecture of the Human Genome. PMID:27135799
Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics. PMID:27134283
APID interactomes: providing proteome-based interactomes with controlled quality for multiple species and derived networks. PMID:27131791
Weighted enrichment method for prediction of transcription regulators from transcriptome and global chromatin immunoprecipitation data. PMID:27131787
The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis. PMID:27131380
Positive Selection and Centrality in the Yeast and Fly Protein-Protein Interaction Networks. PMID:27119079
A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells. PMID:27118403
Hepatitis C Virus Protein Interaction Network Analysis Based on Hepatocellular Carcinoma. PMID:27115606
Genetics of PCOS: A systematic bioinformatics approach to unveil the proteins responsible for PCOS. PMID:27114910
Global Membrane Protein Interactome Analysis using In vivo Crosslinking and Mass Spectrometry-based Protein Correlation Profiling. PMID:27114452
A Network Pharmacology Approach to Uncover the Pharmacological Mechanism of XuanHuSuo Powder on Osteoarthritis. PMID:27110264
Pooled-matrix protein interaction screens using Barcode Fusion Genetics. PMID:27107012
Network-Based Protein Biomarker Discovery Platforms. PMID:27103885
The adaptive potential of subtropical rainbowfish in the face of climate change: heritability and heritable plasticity for the expression of candidate genes. PMID:27099620
GIANT API: an application programming interface for functional genomics. PMID:27098035
Drug target identification using network analysis: Taking active components in Sini decoction as an example. PMID:27095146
Learning from Co-expression Networks: Possibilities and Challenges. PMID:27092161
Protein-protein interaction analysis for functional characterization of helicases. PMID:27090004
MiRTargetLink--miRNAs, Genes and Interaction Networks. PMID:27089332
NPInter v3.0: an upgraded database of noncoding RNA-associated interactions. PMID:27087310
Comparative Small RNA Analysis of Pollen Development in Autotetraploid and Diploid Rice. PMID:27077850
Combined small RNA and degradome sequencing to identify miRNAs and their targets in response to drought in foxtail millet. PMID:27068810
Photosystem II Repair and Plant Immunity: Lessons Learned from Arabidopsis Mutant Lacking the THYLAKOID LUMEN PROTEIN 18.3. PMID:27064270
Characterization of the direct targets of FOXO transcription factors throughout evolution. PMID:27061590
Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian malignancies: A large-scale meta-analysis. PMID:27057433
The Comparison of Adipose Stem Cell and Placental Stem Cell in Secretion Characteristics and in Facial Antiaging. PMID:27057176
Stress chaperone mortalin regulates human melanogenesis. PMID:27056733
The drug-minded protein interaction database (DrumPID) for efficient target analysis and drug development. PMID:27055828
Proteome-wide dataset supporting functional study of tyrosine kinases in breast cancer. PMID:27054188
Bioinformatic exploration of MTA1-regulated gene networks in colon cancer. PMID:27052252
Specific c-Jun target genes in malignant melanoma. PMID:27050748
Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics. PMID:27050516
A Novel Prioritization Method in Identifying Recurrent Venous Thromboembolism-Related Genes. PMID:27050193
Genic insights from integrated human proteomics in GeneCards. PMID:27048349
Data- and knowledge-based modeling of gene regulatory networks: an update. PMID:27047314
Comprehensive Genome-Wide Transcriptomic Analysis of Immature Articular Cartilage following Ischemic Osteonecrosis of the Femoral Head in Piglets. PMID:27045355
SoftPanel: a website for grouping diseases and related disorders for generation of customized panels. PMID:27044653
Combining systems pharmacology, transcriptomics, proteomics, and metabolomics to dissect the therapeutic mechanism of Chinese herbal Bufei Jianpi formula for application to COPD. PMID:27042044
Using biological networks to integrate, visualize and analyze genomics data. PMID:27036106
Identifying Cancer Subtypes from miRNA-TF-mRNA Regulatory Networks and Expression Data. PMID:27035433
Gene Prioritization by Integrated Analysis of Protein Structural and Network Topological Properties for the Protein-Protein Interaction Network of Neurological Disorders. PMID:27034906
An evolutionary roadmap to the microtubule-associated protein MAP Tau. PMID:27030133
TWEAK-Fn14 Signaling Activates Myofibroblasts to Drive Progression of Fibrotic Kidney Disease. PMID:27026366
Ion mobility-enhanced MS(E)-based label-free analysis reveals effects of low-dose radiation post contextual fear conditioning training on the mouse hippocampal proteome. PMID:27020882
DNA methylation profiling reveals differences in the 3 human monocyte subsets and identifies uremia to induce DNA methylation changes during differentiation. PMID:27018948
Transcriptomic Characterization of Tambaqui (Colossoma macropomum, Cuvier, 1818) Exposed to Three Climate Change Scenarios. PMID:27018790
Proteomics-Based Analysis of Protein Complexes in Pluripotent Stem Cells and Cancer Biology. PMID:27011181
Illuminating drug action by network integration of disease genes: a case study of myocardial infarction. PMID:27004607
FlyOde - a platform for community curation and interactive visualization of dynamic gene regulatory networks in Drosophila eye development. PMID:26998229
MONGKIE: an integrated tool for network analysis and visualization for multi-omics data. PMID:26987515
Prediction of the molecular mechanisms and potential therapeutic targets for diabetic nephropathy by bioinformatics methods. PMID:26986014
Protein S-Glutathionylation Mediates Macrophage Responses to Metabolic Cues from the Extracellular Environment. PMID:26984580
Distinct Biochemical Activities of Eyes absent During Drosophila Eye Development. PMID:26980695
PhyloPro2.0: a database for the dynamic exploration of phylogenetically conserved proteins and their domain architectures across the Eukarya. PMID:26980519
Spatiotemporal variation of mammalian protein complex stoichiometries. PMID:26975353
Relevance of the Axis Spermidine/eIF5A for Plant Growth and Development. PMID:26973686
Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. PMID:26973658
The proteome and phosphoproteome of maize pollen uncovers fertility candidate proteins. PMID:26969016
PIPINO: A Software Package to Facilitate the Identification of Protein-Protein Interactions from Affinity Purification Mass Spectrometry Data. PMID:26966684
A Quantitative Proteomic Analysis of Urine from Gamma-Irradiated Non-Human Primates. PMID:26962295
Efficient and biologically relevant consensus strategy for Parkinson's disease gene prioritization. PMID:26961748
Characterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses. PMID:26951071
MoCha: Molecular Characterization of Unknown Pathways. PMID:26950055
Genetic Network Inference Using Hierarchical Structure. PMID:26941653
Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance. PMID:26938218
Proteomic analysis of SETD6 interacting proteins. PMID:26937450
An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer. PMID:26921330
High-throughput proteomics reveal alarmins as amplifiers of tissue pathology and inflammation after spinal cord injury. PMID:26899371
A Novel Systems-Biology Algorithm for the Analysis of Coordinated Protein Responses Using Quantitative Proteomics. PMID:26893027
Activation of the TGFβ pathway impairs endothelial to haematopoietic transition. PMID:26891705
A Systems Biology Approach to the Coordination of Defensive and Offensive Molecular Mechanisms in the Innate and Adaptive Host-Pathogen Interaction Networks. PMID:26881892
Different Modes of Hydrogen Peroxide Action During Seed Germination. PMID:26870076
Evolution and Functional Insights of Different Ancestral Orthologous Clades of Chitin Synthase Genes in the Fungal Tree of Life. PMID:26870058
The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems. PMID:26869505
Sample preparation protocol for bottom-up proteomic analysis of the secretome of the islets of Langerhans. PMID:26863548
In Silico Analysis of the Structural and Biochemical Features of the NMD Factor UPF1 in Ustilago maydis. PMID:26863136
Different Gene Expression Signatures in Children and Adults with Celiac Disease. PMID:26859134
Genome stability of Propionibacterium acnes: a comprehensive study of indels and homopolymeric tracts. PMID:26857276
Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations. PMID:26848861
Prioritization of Susceptibility Genes for Ectopic Pregnancy by Gene Network Analysis. PMID:26840308
HSP60 plays a regulatory role in IL-1β-induced microglial inflammation via TLR4-p38 MAPK axis. PMID:26838598
The Bioinformatics Report of Mutation Outcome on NADPH Flavin Oxidoreductase Protein Sequence in Clinical Isolates of H. pylori. PMID:26821239
Root Type-Specific Reprogramming of Maize Pericycle Transcriptomes by Local High Nitrate Results in Disparate Lateral Root Branching Patterns. PMID:26811190
Unraveling Molecular Differences of Gastric Cancer by Label-Free Quantitative Proteomics Analysis. PMID:26805816
Semantic interrogation of a multi knowledge domain ontological model of tendinopathy identifies four strong candidate risk genes. PMID:26804977
A Systems Biology Approach to Reveal Putative Host-Derived Biomarkers of Periodontitis by Network Topology Characterization of MMP-REDOX/NO and Apoptosis Integrated Pathways. PMID:26793622
Microarray Meta-Analysis Focused on the Response of Genes Involved in Redox Homeostasis to Diverse Abiotic Stresses in Rice. PMID:26793229
The Immune Syntax Revisited: Opening New Windows on Language Evolution. PMID:26793054
Gene set enrichment and topological analyses based on interaction networks in pediatric acute lymphoblastic leukemia. PMID:26788135
A comprehensive gene expression analysis at sequential stages of in vitro cardiac differentiation from isolated MESP1-expressing-mesoderm progenitors. PMID:26783251
Developmental Nuclear Localization and Quantification of GFP-Tagged EB1c in Arabidopsis Root Using Light-Sheet Microscopy. PMID:26779221
3DIANA: 3D Domain Interaction Analysis: A Toolbox for Quaternary Structure Modeling. PMID:26772592
Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis. PMID:26766440
Proteomic Analysis of Epithelial to Mesenchymal Transition (EMT) Reveals Cross-talk between SNAIL and HDAC1 Proteins in Breast Cancer Cells. PMID:26764010
Bioinformatic landscapes for plant transcription factor system research. PMID:26719053
Prediction of Intra-Species Protein-Protein Interactions in Enteropathogens Facilitating Systems Biology Study. PMID:26717407
HitPredict version 4: comprehensive reliability scoring of physical protein-protein interactions from more than 100 species. PMID:26708988
Reactive Oxygen Species (ROS)-Activated ATM-Dependent Phosphorylation of Cytoplasmic Substrates Identified by Large-Scale Phosphoproteomics Screen. PMID:26699800
Genome-wide analysis of DNA methylation associated with HIV infection based on a pair of monozygotic twins. PMID:26697319
A comparison of the transcriptome of Drosophila melanogaster in response to entomopathogenic fungus, ionizing radiation, starvation and cold shock. PMID:26694630
Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules. PMID:26691022
Bioinformatics Mining and Modeling Methods for the Identification of Disease Mechanisms in Neurodegenerative Disorders. PMID:26690135
Fundamentals of protein interaction network mapping. PMID:26681426
Identification of aberrant gene expression associated with aberrant promoter methylation in primordial germ cells between E13 and E16 rat F3 generation vinclozolin lineage. PMID:26677731
Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. PMID:26673326
The Proteomic Profile of Deleted in Breast Cancer 1 (DBC1) Interactions Points to a Multifaceted Regulation of Gene Expression. PMID:26657080
SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat. PMID:26637528
Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death. PMID:26635802
COMBREX-DB: an experiment centered database of protein function: knowledge, predictions and knowledge gaps. PMID:26635392
Bioinformatics Analysis of the Effects of Tobacco Smoke on Gene Expression. PMID:26629988
PC-TraFF: identification of potentially collaborating transcription factors using pointwise mutual information. PMID:26627005
Comparative proteomic analysis of compartmentalised Ras signalling. PMID:26620772
cDNA Library Screening Identifies Protein Interactors Potentially Involved in Non-Telomeric Roles of Arabidopsis Telomerase. PMID:26617625
The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases. PMID:26615188
SVD-phy: improved prediction of protein functional associations through singular value decomposition of phylogenetic profiles. PMID:26614125
Mining for Candidate Genes Related to Pancreatic Cancer Using Protein-Protein Interactions and a Shortest Path Approach. PMID:26613085
Did we learn something new on pemphigoid autoimmune blistering diseases? PMID:26612397
Intein Clustering Suggests Functional Importance in Different Domains of Life. PMID:26609079
Impact of microRNA-130a on the neutrophil proteome. PMID:26608132
Lynx: a knowledge base and an analytical workbench for integrative medicine. PMID:26590263
STITCH 5: augmenting protein-chemical interaction networks with tissue and affinity data. PMID:26590256
Genetic determinants of fibro-osseous lesions in aged inbred mice. PMID:26589134
eggNOG 4.5: a hierarchical orthology framework with improved functional annotations for eukaryotic, prokaryotic and viral sequences. PMID:26582926
Gene3D: expanding the utility of domain assignments. PMID:26578585
Enhanced annotations and features for comparing thousands of Pseudomonas genomes in the Pseudomonas genome database. PMID:26578582
dbPTM 2016: 10-year anniversary of a resource for post-translational modification of proteins. PMID:26578568
GEneSTATION 1.0: a synthetic resource of diverse evolutionary and functional genomic data for studying the evolution of pregnancy-associated tissues and phenotypes. PMID:26567549
Conserved Molecular Underpinnings and Characterization of a Role for Caveolin-1 in the Tumor Microenvironment of Mature T-Cell Lymphomas. PMID:26566034
Human TNF-α induces differential protein phosphorylation in Schistosoma mansoni adult male worms. PMID:26547565
Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique. PMID:26530046
MouseNet v2: a database of gene networks for studying the laboratory mouse and eight other model vertebrates. PMID:26527726
Survey of Natural Language Processing Techniques in Bioinformatics. PMID:26525745
Integrated interactions database: tissue-specific view of the human and model organism interactomes. PMID:26516188
Proteomic profiling of nuclear fractions from native renal inner medullary collecting duct cells. PMID:26508704
Tetraspan cargo adaptors usher GPI-anchored proteins into multivesicular bodies. PMID:26505929
Moving from capstones toward cornerstones: successes and challenges in applying systems biology to identify mechanisms of autism spectrum disorders. PMID:26500678
Nonsynonymous Single-Nucleotide Variations on Some Posttranslational Modifications of Human Proteins and the Association with Diseases. PMID:26495027
CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment. PMID:26491539
Protein Analysis of Sapienic Acid-Treated Porphyromonas gingivalis Suggests Differential Regulation of Multiple Metabolic Pathways. PMID:26483519
A phylogenomic analysis of the role and timing of molecular adaptation in the aquatic transition of cetartiodactyl mammals. PMID:26473040
Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells. PMID:26462736
Prediction of microbial phenotypes based on comparative genomics. PMID:26451672
Mining protein interactomes to improve their reliability and support the advancement of network medicine. PMID:26442112
Molecular identity of human outer radial glia during cortical development. PMID:26406371
CRC-113 gene expression signature for predicting prognosis in patients with colorectal cancer. PMID:26397224
The outer mucus layer hosts a distinct intestinal microbial niche. PMID:26392213
Decoding protein networks during virus entry by quantitative proteomics. PMID:26365680
A systematic screening to identify de novo mutations causing sporadic early-onset Parkinson's disease. PMID:26362251
Cerebrospinal Fluid Biomarkers of Japanese Encephalitis. PMID:26309732
The effect of acute and long-term physical activity on extracellular matrix and serglycin in human skeletal muscle. PMID:26290530
cyNeo4j: connecting Neo4j and Cytoscape. PMID:26272981
Proteins of Unknown Biochemical Function: A Persistent Problem and a Roadmap to Help Overcome It. PMID:26269542
Functional and Structural Impact of ATP-Binding Cassette Transporter A1 R219K and I883M Gene Polymorphisms in Obese Children and Adolescents. PMID:26243156
BMP Inhibition in Seminomas Initiates Acquisition of Pluripotency via NODAL Signaling Resulting in Reprogramming to an Embryonal Carcinoma. PMID:26226633
The power of operon rearrangements for predicting functional associations. PMID:26199682
Losartan ameliorates dystrophic epidermolysis bullosa and uncovers new disease mechanisms. PMID:26194911
DDX3X Biomarker Correlates with Poor Survival in Human Gliomas. PMID:26184164
A proteomic profiling of laser-microdissected lung adenocarcinoma cells of early lepidic-types. PMID:26162278
Comparative studies of mitochondrial proteomics reveal an intimate protein network of male sterility in wheat (Triticum aestivum L.). PMID:26136264
A comprehensive quantitative phosphoproteome analysis of rice in response to bacterial blight. PMID:26112675
AtPGL3 is an Arabidopsis BURP domain protein that is localized to the cell wall and promotes cell enlargement. PMID:26106400
RPGR: Its role in photoreceptor physiology, human disease, and future therapies. PMID:26093275
YM155, a survivin suppressant, triggers PARP-dependent cell death (parthanatos) and inhibits esophageal squamous-cell carcinoma xenografts in mice. PMID:26090615
Study of phosphorylation events for cancer diagnoses and treatment. PMID:26055493
Biological Relevance and Therapeutic Potential of the Hypusine Modification System. PMID:26037925
A comprehensive map of genome-wide gene regulation in Mycobacterium tuberculosis. PMID:25977815
SELPHI: correlation-based identification of kinase-associated networks from global phospho-proteomics data sets. PMID:25948583
Human cytomegalovirus pUL97 kinase induces global changes in the infected cell phosphoproteome. PMID:25867546
Fungal metabolic gene clusters-caravans traveling across genomes and environments. PMID:25784900
An event-driven approach for studying gene block evolution in bacteria. PMID:25717195
Version 4.0 of PaxDb: Protein abundance data, integrated across model organisms, tissues, and cell-lines. PMID:25656970
Genome-scale identification and characterization of moonlighting proteins. PMID:25497125 -
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible
PubMed citations: 2865.
2865 articles citing: The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible
CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns. PMID:35918315
Network-Based Pharmacology and Bioinformatics Study on the Mechanism of Action of Gujiansan in the Treatment of Steroid-Induced Avascular Necrosis of the Femoral Head. PMID:35915795
Application of weighted co-expression network analysis and machine learning to identify the pathological mechanism of Alzheimer's disease. PMID:35912089
Mechanism and Molecular Targets of Ejiao Siwu Decoction for Treating Primary Immune Thrombocytopenia Based on High-Performance Liquid Chromatograph, Network Pharmacology, Molecular Docking and Cytokines Validation. PMID:35911404
An integrative transcriptome analysis reveals potential predictive, prognostic biomarkers and therapeutic targets in colorectal cancer. PMID:35907803
A Pilot Mitochondrial Genome-Wide Association on Migraine Among Saudi Arabians. PMID:35903646
Dysregulation of Tweak and Fn14 in skeletal muscle of spinal muscular atrophy mice. PMID:35902978
Lipid-related FABP5 activation of tumor-associated monocytes fosters immune privilege via PD-L1 expression on Treg cells in hepatocellular carcinoma. PMID:35902729
Repurposing Drugs via Network Analysis: Opportunities for Psychiatric Disorders. PMID:35890359
Analyzing the Systems Biology Effects of COVID-19 mRNA Vaccines to Assess Their Safety and Putative Side Effects. PMID:35889989
Statistical Bioinformatics to Uncover the Underlying Biological Mechanisms That Linked Smoking with Type 2 Diabetes Patients Using Transcritpomic and GWAS Analysis. PMID:35889263
STAT3 and NTRK2 Genes Predicted by the Bioinformatics Approach May Play Important Roles in the Pathogenesis of Multiple Sclerosis and Obsessive-Compulsive Disorder. PMID:35887540
Identification of Differential Expression Genes between Volume and Pressure Overloaded Hearts Based on Bioinformatics Analysis. PMID:35886059
Identifying Genes Related to Acute Myocardial Infarction Based on Network Control Capability. PMID:35886020
Integrated Analysis of LncRNA-Mediated ceRNA Network in Calcific Aortic Valve Disease. PMID:35883646
Sexually Dimorphic Increases in Bone Mass Following Tissue-specific Overexpression of Runx1 in Osteoclast Precursors. PMID:35880727
Inflammation in Preeclampsia: Genetic Biomarkers, Mechanisms, and Therapeutic Strategies. PMID:35880174
Pathogenomic in silico approach identifies NSP-A and Fe-IIISBP as possible drug targets in Neisseria Meningitidis MC58 and development of pharmacophores as novel therapeutic candidates. PMID:35879631
New Retinal Pigment Epithelial Cell Model to Unravel Neuroprotection Sensors of Neurodegeneration in Retinal Disease. PMID:35873810
SNP-to-gene linking strategies reveal contributions of enhancer-related and candidate master-regulator genes to autoimmune disease. PMID:35873673
Global Integrated Genomic and Transcriptomic Analyses of MYB Transcription Factor Superfamily in C3 Model Plant Oryza sativa (L.) Unravel Potential Candidates Involved in Abiotic Stress Signaling. PMID:35873492
Identification and Validation of a Potential Stemness-Associated Biomarker in Hepatocellular Carcinoma. PMID:35859724
Appetite regulating genes in zebrafish gut; a gene expression study. PMID:35853004
Comprehensive Pan-Cancer Analysis of TRPM8 in Tumor Metabolism and Immune Escape. PMID:35847920
Chicken-Specific Kinome Analysis of Early Host Immune Signaling Pathways in the Cecum of Newly Hatched Chickens Infected With Salmonella enterica Serovar Enteritidis. PMID:35846741
Diagnostic and prognostic potential clustered miRNAs in bladder cancer. PMID:35845108
Bioinformatics role of the WGCNA analysis and co-expression network identifies of prognostic marker in lung cancer. PMID:35844396
Identifying significant genes and functionally enriched pathways in familial hypercholesterolemia using integrated gene co-expression network analysis. PMID:35844366
Identifying the focuses of hereditary gingival fibromatosis with bioinformatics strategies. PMID:35836867
Epithelial to Mesenchymal Transition Relevant Subtypes with Distinct Prognosis and Responses to Chemo- or Immunotherapies in Osteosarcoma. PMID:35836470
Comprehensive transcriptomic and co-expression analysis of ABL1 gene and molecularly targeted drugs in hepatocellular carcinoma based on multi-database mining. PMID:35834027
Clinicopathological characteristics and prognostic significance of HDAC11 protein expression in non-small cell lung cancer: a retrospective study. PMID:35832445
Integrated Analysis and Identification of CSF-Derived Risk miRNAs and Pivotal Genes in Multiple Sclerosis. PMID:35819635
Identification of potential biomarkers and immune infiltration characteristics in severe asthma. PMID:35817495
Comprehensive Analysis of Role of Cyclin-Dependent Kinases Family Members in Colorectal Cancer. PMID:35814446
Transmembrane Transporter Sema3D Serves as a Tumor Suppressor in Localized Clear Cell Renal Cell Carcinoma. PMID:35813868
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma. PMID:35813482
eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury. PMID:35812318
COL5A1 Promotes the Progression of Gastric Cancer by Acting as a ceRNA of miR-137-3p to Upregulate FSTL1 Expression. PMID:35805015
[Therapeutic mechanism of emodin for treatment of rheumatoid arthritis: a network pharmacology-based analysis]. PMID:35790443
ATRPred: A machine learning based tool for clinical decision making of anti-TNF treatment in rheumatoid arthritis patients. PMID:35788746
Integrated Analysis of Immune-Related circRNA-miRNA-mRNA Regulatory Network in Ischemic Stroke. PMID:35785353
Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis. PMID:35785034
Construction of a Novel circRNA/miRNA/mRNA Regulatory Network to Explore the Potential Pathogenesis of Wilson's Disease. PMID:35784724
Comprehensive Proteomics Profiling Identifies Patients With Late Gadolinium Enhancement on Cardiac Magnetic Resonance Imaging in the Hypertrophic Cardiomyopathy Population. PMID:35783832
A Novel Overall Survival Prediction Signature Based on Comprehensive Research in Prostate Cancer Bone Metastases. PMID:35783639
Recognition of Key Genes in Human Anaplastic Thyroid Cancer via the Weighing Gene Coexpression Network. PMID:35782055
Extended disordered regions of ribosome-associated NAC proteins paralogs belong only to the germline in Drosophila melanogaster. PMID:35778515
SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates. PMID:35776115
Network Pharmacology and In Vivo Analysis of Dahuang-Huangqi Decoction Effectiveness in Alleviating Renal Interstitial Fibrosis. PMID:35774743
Decreased synapse-associated proteins are associated with the onset of epileptic memory impairment in endothelial CDK5-deficient mice. PMID:35770064
Identification of hub genes predicting the development of prostate cancer from benign prostate hyperplasia and analyzing their clinical value in prostate cancer by bioinformatic analysis. PMID:35768705
Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal-fetal interface. PMID:35764880
Exosomes derived from magnetically actuated bone mesenchymal stem cells promote tendon-bone healing through the miR-21-5p/SMAD7 pathway. PMID:35757032
RNA-Seq Analysis of Magnaporthe grisea Transcriptome Reveals the High Potential of ZnO Nanoparticles as a Nanofungicide. PMID:35755666
Network Pharmacology-Based Investigation of the Molecular Mechanisms of the Chinese Herbal Formula Shenyi in the Treatment of Diabetic Nephropathy. PMID:35755045
Link Prediction on Complex Networks: An Experimental Survey. PMID:35754861
Weighted Gene Co-expression Network Analysis Identifies Specific Modules and Hub Genes Related to Subacute Ruminal Acidosis. PMID:35754546
Shema Oral Liquid Ameliorates the Severity of LPS-Induced COPD via Regulating DNMT1. PMID:35754478
Discovery of Synergistic Drug Combinations for Colorectal Cancer Driven by Tumor Barcode Derived from Metabolomics "Big Data". PMID:35736427
Based on network pharmacology and in vitro experiments to prove the effective inhibition of myocardial fibrosis by Buyang Huanwu decoction. PMID:35726821
Doxycycline Alters the Porcine Renal Proteome and Degradome during Hypothermic Machine Perfusion. PMID:35723325
Deciphering the Active Compounds and Mechanisms of HSBDF for Treating ALI via Integrating Chemical Bioinformatics Analysis. PMID:35721141
Mechanism of Action of Zhi Gan Cao Decoction for Atrial Fibrillation and Myocardial Fibrosis in a Mouse Model of Atrial Fibrillation: A Network Pharmacology-Based Study. PMID:35720023
Multi-view heterogeneous molecular network representation learning for protein-protein interaction prediction. PMID:35710342
Molecular Targets and Mechanisms of Hedyotis diffusa-Scutellaria barbata Herb Pair for the Treatment of Colorectal Cancer Based on Network Pharmacology and Molecular Docking. PMID:35707465
Comprehensive Analysis of the Expression and Prognostic Value of LMAN2 in HER2+ Breast Cancer. PMID:35707004
Transcriptional profile changes after treatment of ischemia reperfusion injury-induced kidney fibrosis with 18β-glycyrrhetinic acid. PMID:35699239
A novel method for assessing and measuring homophily in networks through second-order statistics. PMID:35697749
Genome-wide characterization of copy number variations in diffuse large B-cell lymphoma with implications in targeted therapy. PMID:35693879
Bioinformatic Analysis Identifying PSMB 1/2/3/4/6/8/9/10 as Prognostic Indicators in Clear Cell Renal Cell Carcinoma. PMID:35693739
Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis. PMID:35692536
Identification of Prognostic Biomarkers of Glioblastoma Based on Multidatabase Integration and Its Correlation with Immune-Infiltration Cells. PMID:35685428
The Auxin-Response Repressor IAA30 Is Down-Regulated in Reproductive Tissues of Apomictic Paspalum notatum. PMID:35684245
Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data. PMID:35680885
Spatial region-resolved proteome map reveals mechanism of COVID-19-associated heart injury. PMID:35679865
SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity. PMID:35674692
[Identification of serological biomarkers for diagnosis of rheumatoid arthritis using a protein array-based approach]. PMID:35673918
GLUT-2 mediated glucose uptake analysis of Duranta repens: In-silico and In-vitro approach. PMID:35673484
Identification of a Diagnostic Signature and Immune Cell Infiltration Characteristics in Keloids. PMID:35669563
Naoluo Xintong Decoction in the Treatment of Ischemic Stroke: A Network Analysis of the Mechanism of Action. PMID:35668929
Computational investigation of benzalacetophenone derivatives against SARS-CoV-2 as potential multi-target bioactive compounds. PMID:35667894
Mechanisms of Gynostemma pentaphyllum against non-alcoholic fibre liver disease based on network pharmacology and molecular docking. PMID:35665440
A Network Pharmacology Analysis of Cytotoxic Triterpenes Isolated from Euphorbia abyssinica Latex Supported by Drug-likeness and ADMET Studies. PMID:35664578
Expression of Protein Acetylation Regulators During Peripheral Nerve Development, Injury, and Regeneration. PMID:35663264
Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology. PMID:35657417
Identification of molecular pathways and protein-protein interactions in adipose tissue-derived mesenchymal stromal cells (ASCs) under physiological oxygen concentration in a diabetic rat model. PMID:35655589
The LINC01929/miR-6875-5p/ADAMTS12 Axis in the ceRNA Network Regulates the Development of Advanced Bladder Cancer. PMID:35646642
Molecular Mechanism of the Effect of Zhizhu Pill on Gastroesophageal Reflux Disease Based on Network Pharmacology and Molecular Docking. PMID:35646148
OmicsNet 2.0: a web-based platform for multi-omics integration and network visual analytics. PMID:35639733
Connectivity in eQTL networks dictates reproducibility and genomic properties. PMID:35637906
Bioinformatic Analysis of Prognostic Value of SNTG2 with Immune Implications in Lung Adenocarcinoma. PMID:35637702
Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer's disease revealed by weighted gene co-expression network analysis. PMID:35637434
Bone marrow stromal cell antigen 2(BST2) suppresses the migration and invasion of trophoblasts in preeclampsia by downregulating matrix metallopeptidase 2(MMP2). PMID:35635087
A Motif-Based Network Analysis of Regulatory Patterns in Doxorubicin Effects on Treating Breast Cancer, a Systems Biology Study. PMID:35633986
Disclosing Potential Key Genes, Therapeutic Targets and Agents for Non-Small Cell Lung Cancer: Evidence from Integrative Bioinformatics Analysis. PMID:35632527
Persistent Properties of a Subpopulation of Cancer Cells Overexpressing the Hedgehog Receptor Patched. PMID:35631574
Dynamics of Connexin 43 Down Modulation in Human Articular Chondrocytes Stimulated by Tumor Necrosis Factor Alpha. PMID:35628386
Identification of Key Prognostic Genes of Triple Negative Breast Cancer by LASSO-Based Machine Learning and Bioinformatics Analysis. PMID:35627287
A High-Copy Suppressor Screen Reveals a Broad Role of Prefoldin-like Bud27 in the TOR Signaling Pathway in Saccharomyces cerevisiae. PMID:35627133
Explore the Effect of Asthma Regulating HIF-1 Pathway on Sperm Quality Based on Rat Model. PMID:35620222
Mechanistic analysis of erectile dysfunction in a depression rat model. PMID:35615771
Investigating the Molecular Mechanism of Quercetin Protecting against Podocyte Injury to Attenuate Diabetic Nephropathy through Network Pharmacology, MicroarrayData Analysis, and Molecular Docking. PMID:35615688
Andrographolide Inhibits ER-Positive Breast Cancer Growth and Enhances Fulvestrant Efficacy via ROS-FOXM1-ER-α Axis. PMID:35615146
The Overexpression of SLC25A13 Predicts Poor Prognosis and Is Correlated with Immune Cell Infiltration in Patients with Skin Cutaneous Melanoma. PMID:35607442
Single-Cell Transcriptomics Uncovers Cellular Heterogeneity, Mechanisms, and Therapeutic Targets for Parkinson's Disease. PMID:35601482
Network Pharmacology and Absolute Bacterial Quantification-Combined Approach to Explore the Mechanism of Tianqi Pingchan Granule Against 6-OHDA-Induced Parkinson's Disease in Rats. PMID:35600818
Identification of Peripheral Blood miRNA Biomarkers in First-Episode Drug-Free Schizophrenia Patients Using Bioinformatics Strategy. PMID:35599275
Modified climbing fiber/Purkinje cell synaptic connectivity in the cerebellum of the neonatal phencyclidine model of schizophrenia. PMID:35588456
Identification of key differential genes in intimal hyperplasia induced by left carotid artery ligation. PMID:35586138
Visual barcodes for clonal-multiplexing of live microscopy-based assays. PMID:35585055
Identification of candidate genes associated with bacterial and viral infections in wild boars hunted in Tuscany (Italy). PMID:35581286
Machine Learning in Causal Inference: Application in Pharmacovigilance. PMID:35579811
Identification of Common Oncogenic Genes and Pathways Both in Osteosarcoma and Ewing's Sarcoma Using Bioinformatics Analysis. PMID:35578666
Immune-Related Biomarkers Associated with Lung Metastasis from the Colorectal Cancer Microenvironment. PMID:35576491
Prediction of Pathogenic Factors in Dysbiotic Gut Microbiomes of Colorectal Cancer Patients Using Reverse Microbiomics. PMID:35574378
Prognostic Risk Signature and Comprehensive Analyses of Endoplasmic Reticulum Stress-Related Genes in Lung Adenocarcinoma. PMID:35571564
Down-Regulation of Insulin Like Growth Factor 1 Involved in Alzheimer's Disease via MAPK, Ras, and FoxO Signaling Pathways. PMID:35571248
BioTAGME: A Comprehensive Platform for Biological Knowledge Network Analysis. PMID:35571058
Gene Expression Profiling of Glioblastoma to Recognize Potential Biomarker Candidates. PMID:35571016
Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients. PMID:35565356
Integrated computational analysis reveals HOX genes cluster as oncogenic drivers in head and neck squamous cell carcinoma. PMID:35562533
The Regulatory Network and Role of the circRNA-miRNA-mRNA ceRNA Network in the Progression and the Immune Response of Wilms Tumor Based on RNA-Seq. PMID:35559038
Downregulation of CRTC1 Is Involved in CUMS-Induced Depression-Like Behavior in the Hippocampus and Its RNA Sequencing Analysis. PMID:35556215
A Computational Approach to Justifying Stratifin as a Candidate Diagnostic and Prognostic Biomarker for Pancreatic Cancer. PMID:35547358
Identification of key gene contributing to vitiligo by immune infiltration. PMID:35535201
Utilizing Network Pharmacology and Molecular Docking Integrated Surface Plasmon Resonance Technology to Investigate the Potential Targets and Mechanisms of Tripterygium wilfordii against Pulmonary Artery Hypertension. PMID:35535154
A novel artificial intelligence protocol to investigate potential leads for Parkinson's disease. PMID:35520357
Proteomics datasets of developing rat brain: Synaptic proteome and SUMO2/3-ylome. PMID:35516005
Tussah silkmoth pupae improve anti-tumor properties of Cordyceps militaris (L.) Link by increasing the levels of major metabolite cordycepin. PMID:35515955
Construction of a lncRNA-associated competing endogenous RNA regulatory network after traumatic brain injury in mouse. PMID:35501920
Urolithin A as a Potential Drug for the Treatment of Spinal Cord Injuries: A Mechanistic Study Using Network Pharmacology Approaches. PMID:35497925
Comparative Analysis of the Chalcone-Flavanone Isomerase Genes in Six Citrus Species and Their Expression Analysis in Sweet Orange (Citrus sinensis). PMID:35495138
Identification of Functional CircRNA-miRNA-mRNA Regulatory Network in Dorsolateral Prefrontal Cortex Neurons of Patients With Cocaine Use Disorder. PMID:35493321
Exploring the therapeutic mechanisms of Cassia glauca in diabetes mellitus through network pharmacology, molecular docking and molecular dynamics. PMID:35492478
Identification of Novel Immune Cell-Relevant Therapeutic Targets and Validation of Roles of TK1 in BMSCs of Systemic Lupus Erythematosus. PMID:35480888
Glycation modulates glutamatergic signaling and exacerbates Parkinson's disease-like phenotypes. PMID:35468899
Machine learning assisted analysis of breast cancer gene expression profiles reveals novel potential prognostic biomarkers for triple-negative breast cancer. PMID:35465161
miRNA Profiling and Its Role in Multi-Omics Regulatory Networks Connected with Somaclonal Variation in Cucumber (Cucumis sativus L.). PMID:35457133
Text-Mining Approach to Identify Hub Genes of Cancer Metastasis and Potential Drug Repurposing to Target Them. PMID:35456223
Comparative analysis of long noncoding RNA and mRNA expression provides insights into adaptation to hypoxia in Tibetan sheep. PMID:35449433
Evolutionary History and Functional Diversification of the JmjC Domain-Containing Histone Demethylase Gene Family in Plants. PMID:35448769
De novo identification of maximally deregulated subnetworks based on multi-omics data with DeRegNet. PMID:35439941
An atlas of posttranslational modifications on RNA binding proteins. PMID:35438783
Identification of Key Genes and Potential Mechanisms Based on the Autophagy Regulatory Network in Osteoclasts Using a Murine Osteoarthritis Model. PMID:35437349
Molecular Signatures of Mitochondrial Complexes Involved in Alzheimer's Disease via Oxidative Phosphorylation and Retrograde Endocannabinoid Signaling Pathways. PMID:35432724
Identification of Potential Core Genes for the Rupture of Intracranial Aneurysms by a Bioinformatics Analysis. PMID:35432454
Analysis of WRKY Resistance Gene Family in Boehmeria nivea (L.) Gaudich: Crosstalk Mechanisms of Secondary Cell Wall Thickening and Cadmium Stress. PMID:35432436
Transcriptome profiling of flower buds of male-sterile lines provides new insights into male sterility mechanism in alfalfa. PMID:35428186
Systematic Characterization of the Clinical Relevance of KPNA4 in Pancreatic Ductal Adenocarcinoma. PMID:35425701
Combination of system biology to probe the anti-viral activity of andrographolide and its derivative against COVID-19. PMID:35424441
Identification and Validation of Immune Cells and Hub Genes in Gastric Cancer Microenvironment. PMID:35422890
In Vitro and In Vivo Studies for the Investigation of γ-Globin Gene Induction by Adhatoda vasica: A Pre-Clinical Study of HbF Inducers for β-Thalassemia. PMID:35422700
Network pharmacology and in vitro testing of Theobroma cacao extract's antioxidative activity and its effects on cancer cell survival. PMID:35421091
Construction Immune Related Feed-Forward Loop Network Reveals Angiotensin II Receptor Blocker as Potential Neuroprotective Drug for Ischemic Stroke. PMID:35419038
InfersentPPI: Prediction of Protein-Protein Interaction Using Protein Sentence Embedding With Gene Ontology Information. PMID:35419026
Interpreting the Pharmacological Mechanisms of Sho-saiko-to on Thyroid Carcinoma through Combining Network Pharmacology and Experimental Evaluation. PMID:35415320
The Emerging Role of E3 Ubiquitin Ligase SMURF2 in the Regulation of Transcriptional Co-Repressor KAP1 in Untransformed and Cancer Cells and Tissues. PMID:35406379
Second-Generation JK-206 Targets the Oncogenic Signal Mediator RHOA in Gastric Cancer. PMID:35406376
The E3 ubiquitin ligase SMURF2 stabilizes RNA editase ADAR1p110 and promotes its adenosine-to-inosine (A-to-I) editing function. PMID:35403872
Construction of MicroRNA-mRNA Regulatory Network in the Molecular Mechanisms of Bleomycin-Induced Pulmonary Fibrosis. PMID:35402615
miRNA-Mediated Low Expression of EPHX3 Is Associated with Poor Prognosis and Tumor Immune Infiltration in Head and Neck Squamous Cell Carcinomas. PMID:35401746
Exploration of the Specific Pathology of HXMM Tablet Against Retinal Injury Based on Drug Attack Model to Network Robustness. PMID:35401181
A new nomogram model for prognosis of hepatocellular carcinoma based on novel gene signature that regulates cross-talk between immune and tumor cells. PMID:35397536
Construction of Bone Metastasis-Specific Regulation Network Based on Prognostic Stemness-Related Signatures in Prostate Cancer. PMID:35392496
Identification of Immune-Related Gene Signature and Prediction of CeRNA Network in Active Ulcerative Colitis. PMID:35392084
Identification of host transcriptome-guided repurposable drugs for SARS-CoV-1 infections and their validation with SARS-CoV-2 infections by using the integrated bioinformatics approaches. PMID:35390032
Genome-wide analysis of somatic noncoding mutation patterns in cancer. PMID:35389777
Exploration of Hanshi Zufei prescription for treatment of COVID-19 based on network pharmacology. PMID:35382000
Ramadan Diurnal Intermittent Fasting Is Associated With Attenuated FTO Gene Expression in Subjects With Overweight and Obesity: A Prospective Cohort Study. PMID:35372458
Development and Validation of Ischemic Events Related Signature After Carotid Endarterectomy. PMID:35372347
Exploration of the Potential Mechanism of Qi Yin San Liang San Decoction in the Treatment of EGFRI-Related Adverse Skin Reactions Using Network Pharmacology and In Vitro Experiments. PMID:35372072
Expression and Regulation Network of HDAC3 in Acute Myeloid Leukemia and the Implication for Targeted Therapy Based on Multidataset Data Mining. PMID:35371279
Proteomic Signatures of Microbial Adaptation to the Highest Ultraviolet-Irradiation on Earth: Lessons From a Soil Actinobacterium. PMID:35369494
Gene expression study in monocytes: evidence of inflammatory dysregulation in early-onset obsessive-compulsive disorder. PMID:35361798
Identifying Active Substances and the Pharmacological Mechanism of Houttuynia cordata Thunb. in Treating Radiation-Induced Lung Injury Based on Network Pharmacology and Molecular Docking Verification. PMID:35360660
INPUT: An intelligent network pharmacology platform unique for traditional Chinese medicine. PMID:35356545
Understanding the role of myoglobin content in Iberian pigs fattened in an extensive system through analysis of the transcriptome profile. PMID:35355298
Identification of CD101 in Glioma: A Novel Prognostic Indicator Expressed on M2 Macrophages. PMID:35350788
Predicting embryonic aneuploidy rate in IVF patients using whole-exome sequencing. PMID:35347416
Exploring the Multicomponent Synergy Mechanism of Yinzhihuang Granule in Inhibiting Inflammation-Cancer Transformation of Hepar Based on Integrated Bioinformatics and Network Pharmacology. PMID:35342754
Mechanism of Zhen Wu Decoction in the Treatment of Heart Failure Based on Network Pharmacology and Molecular Docking. PMID:35341142
Comprehensive proteomic profiling of plasma and serum phosphatidylserine-positive extracellular vesicles reveals tissue-specific proteins. PMID:35340435
Identification of Potential Genes Encoding Protein Transporters in Arabidopsis thaliana Glucosinolate (GSL) Metabolism. PMID:35330077
Correlation Imputation for Single-Cell RNA-seq. PMID:35325552
PCBP2 maintains antiviral signaling homeostasis by regulating cGAS enzymatic activity via antagonizing its condensation. PMID:35322803
Macrophage Paired Immunoglobulin-Like Receptor B Deficiency Promotes Peripheral Atherosclerosis in Apolipoprotein E-Deficient Mice. PMID:35321392
Application of an iPSC-Derived Organoid Model for Localized Scleroderma Therapy. PMID:35315234
Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation. PMID:35314028
Finding New Ways How to Control BACE1. PMID:35305135
Autophagy-Related Genes Predict the Progression of Periodontitis Through the ceRNA Network. PMID:35300213
Exploring the Mechanism of Yiqi Qingre Ziyin Method in Regulating Neuropeptide Expression for the Treatment of Atrophic Rhinitis. PMID:35299869
Comparative Studies to Uncover Mechanisms of Action of N-(1,3,4-Oxadiazol-2-yl)benzamide Containing Antibacterial Agents. PMID:35297603
Long noncoding RNAs regulated spermatogenesis in varicocele-induced spermatogenic dysfunction. PMID:35297519
Bioinformatics and Machine Learning Methods to Identify FN1 as a Novel Biomarker of Aortic Valve Calcification. PMID:35295271
Eucalyptus grandis AUX/INDOLE-3-ACETIC ACID 13 (EgrIAA13) is a novel transcriptional regulator of xylogenesis. PMID:35292886
An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis. PMID:35288533
Protecting effect of emodin in experimental autoimmune encephalomyelitis mice by inhibiting microglia activation and inflammation via Myd88/PI3K/Akt/NF-κB signalling pathway. PMID:35287559
Prediction of the Active Components and Possible Targets of Xanthii Fructus Based on Network Pharmacology for Use in Chronic Rhinosinusitis. PMID:35287308
Revealing Calcium Signaling Pathway as Novel Mechanism of Danhong Injection for Treating Acute Myocardial Infarction by Systems Pharmacology and Experiment Validation. PMID:35281886
Vitamins D2 and D3 Have Overlapping But Different Effects on the Human Immune System Revealed Through Analysis of the Blood Transcriptome. PMID:35281034
HCK is a Potential Prognostic Biomarker that Correlates with Immune Cell Infiltration in Acute Myeloid Leukemia. PMID:35280440
Computational identification of host genomic biomarkers highlighting their functions, pathways and regulators that influence SARS-CoV-2 infections and drug repurposing. PMID:35277538
Comprehensive Analyses of the Immunological and Prognostic Roles of an IQGAP3AR/let-7c-5p/IQGAP3 Axis in Different Types of Human Cancer. PMID:35274003
Comprehensive Analysis of the Prognosis and Drug Sensitivity of Differentiation-Related lncRNAs in Papillary Thyroid Cancer. PMID:35267662
A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts. PMID:35263568
In silico discovery of 3 novel quercetin derivatives against papain-like protease, spike protein, and 3C-like protease of SARS-CoV-2. PMID:35262828
The role of NAD and NAD precursors on longevity and lifespan modulation in the budding yeast, Saccharomyces cerevisiae. PMID:35260986
Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions. PMID:35259090
Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration. PMID:35259089
Identification of Potential Key Biomarkers and Immune Infiltration in Oral Lichen Planus. PMID:35256894
Invertebrate Model Organisms as a Platform to Investigate Rare Human Neurological Diseases. PMID:35256540
Transcriptome Analysis of Plasmodium falciparum Isolates From Benin Reveals Specific Gene Expression Associated With Cerebral Malaria. PMID:35255125
Integrated Chromatin Accessibility and Transcriptome Landscapes of 5-Fluorouracil-Resistant Colon Cancer Cells. PMID:35252200
Effects of Lactobacillus acidophilus KLDS1.0901 on Proliferation and Apoptosis of Colon Cancer Cells. PMID:35250903
A novel high throughput screen to identify candidate molecular networks that regulate spermatogenic stem cell functions†. PMID:35244684
Identification of Crucial Genes and Key Functions in Type 2 Diabetic Hearts by Bioinformatic Analysis. PMID:35242109
Network analysis of atherosclerotic genes elucidates druggable targets. PMID:35241081
Rapid evolution fuels transcriptional plasticity to ocean acidification. PMID:35238117
An Integrated Pharmacology-Based Strategy to Investigate the Potential Mechanism of Xiebai San in Treating Pediatric Pneumonia. PMID:35237157
Identification of the Hub Genes and the Signaling Pathways in Human iPSC-Cardiomyocytes Infected by SARS-CoV-2. PMID:35235083
CFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis. PMID:35234914
Potential biomarkers in the fibrosis progression of nonalcoholic steatohepatitis (NASH). PMID:35226336
Identification of Hub Genes in Pancreatic Ductal Adenocarcinoma Using Bioinformatics Analysis. PMID:35223598
Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data. PMID:35222843
High Expression of PLAGL2 is Associated With Poor Prognosis in High-Grade Glioma. PMID:35222518
LPIN1 Is a Regulatory Factor Associated With Immune Response and Inflammation in Sepsis. PMID:35222395
Plasma Concentration of Tumor Necrosis Factor-Stimulated Gene-6 as a Novel Diagnostic and 3-Month Prognostic Indicator in Non-Cardioembolic Acute Ischemic Stroke. PMID:35222359
Identification of Molecular Signatures and Candidate Drugs in Vascular Dementia by Bioinformatics Analyses. PMID:35221911
Pseudogene AK4P1 promotes pancreatic ductal adenocarcinoma progression through relieving miR-375-mediated YAP1 degradation. PMID:35220277
DeepWalk based method to predict lncRNA-miRNA associations via lncRNA-miRNA-disease-protein-drug graph. PMID:35216549
Urinary Proteomic Signature in Acute Decompensated Heart Failure: Advances into Molecular Pathophysiology. PMID:35216460
Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets. PMID:35215294
Integration of Transcriptome and Exome Genotyping Identifies Significant Variants with Autism Spectrum Disorder. PMID:35215271
Mining GEO and TCGA Database for Immune Microenvironment of Lung Squamous Cell Carcinoma Patients With or Without Chemotherapy. PMID:35211415
Unlocking the Memory Component of Alzheimer's Disease: Biological Processes and Pathways across Brain Regions. PMID:35204764
Comprehensive analysis of the MIR4435-2HG/miR-1-3p/MMP9/miR-29-3p/DUXAP8 ceRNA network axis in hepatocellular carcinoma. PMID:35201491
Identification of Potential Cytokinin Responsive Key Genes in Rice Treated With Trans-Zeatin Through Systems Biology Approach. PMID:35198001
Elasnin Effectively Eradicates Daptomycin-Resistant Methicillin-Resistant Staphylococcus aureus Biofilms. PMID:35196789
THRSP identified as a potential hepatocellular carcinoma marker by integrated bioinformatics analysis and experimental validation. PMID:35196258
Elastin, arterial mechanics, and stenosis. PMID:35196168
Single-Cell Sequencing Facilitates Elucidation of HIV Immunopathogenesis: A Review of Current Literature. PMID:35185920
S100A12 as Biomarker of Disease Severity and Prognosis in Patients With Idiopathic Pulmonary Fibrosis. PMID:35185901
Characterization of Interplay Between Autophagy and Ferroptosis and Their Synergistical Roles on Manipulating Immunological Tumor Microenvironment in Squamous Cell Carcinomas. PMID:35185859
Olfactory receptors contribute to progression of kidney fibrosis. PMID:35181660
A Network Pharmacology Study on the Active Components and Targets of the Radix Ginseng and Radix Bupleuri Herb Pair for Treating Nonalcoholic Fatty Liver Disease. PMID:35178098
Aberrant Expression of ADARB1 Facilitates Temozolomide Chemoresistance and Immune Infiltration in Glioblastoma. PMID:35177985
Mechanisms of magnoliae cortex on treating sarcopenia explored by GEO gene sequencing data combined with network pharmacology and molecular docking. PMID:35176999
ASF1B: A Possible Prognostic Marker, Therapeutic Target, and Predictor of Immunotherapy in Male Thyroid Carcinoma. PMID:35174076
Mechanism of action of Tripterygium wilfordii for treatment of idiopathic membranous nephropathy based on network pharmacology. PMID:35172688
Prognostic and immune-related value of STK17B in skin cutaneous melanoma. PMID:35171924
eNAMPT Is a Novel Damage-associated Molecular Pattern Protein That Contributes to the Severity of Radiation-induced Lung Fibrosis. PMID:35167418
Label-Free Quantitative Proteomics to Explore the Action Mechanism of the Pharmaceutical-Grade Triticum vulgare Extract in Speeding Up Keratinocyte Healing. PMID:35164377
Dual RNA Sequencing of Mycobacterium tuberculosis-Infected Human Splenic Macrophages Reveals a Strain-Dependent Host-Pathogen Response to Infection. PMID:35163725
The Cumulative Formation of R-loop Interacts with Histone Modifications to Shape Cell Reprogramming. PMID:35163490
Novel Possible Protein Targets in Neovascular Age-Related Macular Degeneration: A Pilot Study Experiment. PMID:35155457
Assessment of colon cancer molecular mechanism: a system biology approach. PMID:35154602
Cross-Talking Pathways of Forkhead Box O1 (FOXO1) Are Involved in the Pathogenesis of Alzheimer's Disease and Huntington's Disease. PMID:35154571
An Augmented High-Dimensional Graphical Lasso Method to Incorporate Prior Biological Knowledge for Global Network Learning. PMID:35154240
Effects of Multispecies Probiotic on Intestinal Microbiota and Mucosal Barrier Function of Neonatal Calves Infected With E. coli K99. PMID:35154038
Network Pharmacology and Molecular Docking-Based Mechanism Study to Reveal the Protective Effect of Salvianolic Acid C in a Rat Model of Ischemic Stroke. PMID:35153756
Machine learning prediction and tau-based screening identifies potential Alzheimer's disease genes relevant to immunity. PMID:35149761
Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease. PMID:35148841
Maternal Blood-Based Protein Biomarkers in Relation to Abdominal Fat Distribution Measured by Ultrasound in Early Mid-Pregnancy. PMID:35147910
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation. PMID:35140607
Transcriptome-wide changes in gene expression, splicing, and lncRNAs in response to a live attenuated dengue virus vaccine. PMID:35139383
The DOMINO web-server for active module identification analysis. PMID:35139202
Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles. PMID:35132167
Identification of circular RNAs and functional competing endogenous RNA networks in human proximal tubular epithelial cells treated with sodium-glucose cotransporter 2 inhibitor dapagliflozin in diabetic kidney disease. PMID:35129424
Identification of Potential Key Genes and Molecular Mechanisms of Medulloblastoma Based on Integrated Bioinformatics Approach. PMID:35127939
Lentinan Supplementation Protects the Gut-Liver Axis and Prevents Steatohepatitis: The Role of Gut Microbiota Involved. PMID:35127789
Gemcitabine-Resistant Biomarkers in Bladder Cancer are Associated with Tumor-Immune Microenvironment. PMID:35127724
Dysfunctional Network and Mutation Genes of Hypertrophic Cardiomyopathy. PMID:35126952
PGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis. PMID:35121728
Construction and integrated analysis of a lncRNA-associated competing endogenous RNA network reveal functional lncRNAs in pancreatic cancer. PMID:35117727
Screening of potential genes and transcription factors involved in post-radiation cognitive dysfunction in mice via bioinformatics. PMID:35117246
CDCA1/2/3/5/7/8 as novel prognostic biomarkers and CDCA4/6 as potential targets for gastric cancer. PMID:35116645
An investigation to identify tumor microenvironment-related genes of prognostic value in lung squamous cell carcinoma based on The Cancer Genome Atlas. PMID:35116510
A comprehensive bioinformatics analysis to identify a candidate prognostic biomarker for ovarian cancer. PMID:35116478
Identification of key genes and pathways at the downstream of S100PBP in pancreatic cancer cells by integrated bioinformatical analysis. PMID:35116411
Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia. PMID:35111390
Network Pharmacology-Based Analysis on Lonicera japonica for Chronic Osteomyelitis Treatment. PMID:35111224
Screening of Important Markers in Peripheral Blood Mononuclear Cells to Predict Female Osteoporosis Risk Using LASSO Regression Algorithm and SVM Method. PMID:35110962
Expression profiles and functions of ferroptosis-related genes in the placental tissue samples of early- and late-onset preeclampsia patients. PMID:35100981
Dissecting the heterogeneity of the microenvironment in primary and recurrent nasopharyngeal carcinomas using single-cell RNA sequencing. PMID:35096485
Downregulation of PIK3CB Involved in Alzheimer's Disease via Apoptosis, Axon Guidance, and FoxO Signaling Pathway. PMID:35096262
Immune microenvironment-related gene mapping predicts immunochemotherapy response and prognosis in diffuse large B-cell lymphoma. PMID:35092504
Investigation of molecular regulation mechanism under the pathophysiology of subarachnoid hemorrhage. PMID:35087950
Predictability and parallelism in the contemporary evolution of hybrid genomes. PMID:35085234
Transcription factor motif activity as a biomarker of muscle aging. PMID:35083472
Proteomic screen reveals diverse protein transport between connected neurons in the visual system. PMID:35081342
Colistin exposure enhances expression of eptB in colistin-resistant Escherichia coli co-harboring mcr-1. PMID:35079093
CKMT1A is a novel potential prognostic biomarker in patients with endometrial cancer. PMID:35077462
MetaNetwork Enhances Biological Insights from Quantitative Proteomics Differences by Combining Clustering and Enrichment Analyses. PMID:35073098
Identification of Molecular Biomarkers and Key Pathways for Esophageal Carcinoma (EsC): A Bioinformatics Approach. PMID:35071597
The establishment of a hub differential gene model to predict prognosis in stage II and III right- and left-sided colon cancer patients. PMID:35071457
Network-Based Approach and IVI Methodologies, a Combined Data Investigation Identified Probable Key Genes in Cardiovascular Disease and Chronic Kidney Disease. PMID:35071341
High expression of Ran binding protein 1 predicts poor outcomes in hepatocellular carcinoma patients: a Cancer Genome Atlas database analysis. PMID:35070423
Violations of proportional hazard assumption in Cox regression model of transcriptomic data in TCGA pan-cancer cohorts. PMID:35070171
Comparison between Heat-Clearing Medicine and Antirheumatic Medicine in Treatment of Gastric Cancer Based on Network Pharmacology, Molecular Docking, and Tumor Immune Infiltration Analysis. PMID:35069767
Gene expression profiling using targeted RNA-sequencing to elucidate the progression from histologically normal lung tissues to non-invasive lesions in invasive lung adenocarcinoma. PMID:35067776
Protein turnover models for LC-MS data of heavy water metabolic labeling. PMID:35062023
Impact of circ-0000221 in the Pathogenesis of Hepatocellular via Modulation of miR-661-PTPN11 mRNA Axis. PMID:35057034
Towards an Ideal In Cell Hybridization-Based Strategy to Discover Protein Interactomes of Selected RNA Molecules. PMID:35055128
Epigenome-Wide DNA Methylation Profiling in Colorectal Cancer and Normal Adjacent Colon Using Infinium Human Methylation 450K. PMID:35054365
2',3'-cAMP treatment mimics the stress molecular response in Arabidopsis thaliana. PMID:35043968
Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2. PMID:35042863
A novel epithelial-mesenchymal transition-related gene signature for prognosis prediction in patients with lung adenocarcinoma. PMID:35036605
NF-κB-Related Metabolic Gene Signature Predicts the Prognosis and Immunotherapy Response in Gastric Cancer. PMID:35036435
Integrated analysis and the identification of a circRNA-miRNA-mRNA network in the progression of abdominal aortic aneurysm. PMID:35036156
Systematic Understanding of Mechanism of Danggui Shaoyao San against Ischemic Stroke Using a Network Pharmacology Approach. PMID:35035503
The functions and prognostic value of Krüppel-like factors in breast cancer. PMID:35033064
A transcriptomic analysis of neuropathic pain in the anterior cingulate cortex after nerve injury. PMID:35030976
Bioinformation Analysis Reveals IFIT1 as Potential Biomarkers in Central Nervous System Tuberculosis. PMID:35027832
Inferring early-life host and microbiome functions by mass spectrometry-based metaproteomics and metabolomics. PMID:35024099
Genetic Pathways Involved in the Pathogenesis of Parkinson's Disease. PMID:35023107
Hyperphosphorylation of HDAC2 promotes drug resistance in a novel dual drug resistant mouse melanoma cell line model: an in vitro study. PMID:35018231
Insights into cell robustness against lignocellulosic inhibitors and insoluble solids in bioethanol production processes. PMID:35017613
NETME: on-the-fly knowledge network construction from biomedical literature. PMID:35013714
A de novo paradigm for male infertility. PMID:35013161
Using dual-network-analyser for communities detecting in dual networks. PMID:35012460
Potential biomarkers and signaling pathways associated with the pathogenesis of primary salivary gland carcinoma: a bioinformatics study. PMID:35012286
Arabidopsis thaliana Plant Natriuretic Peptide Active Domain Forms Amyloid-like Fibrils in a pH-Dependent Manner. PMID:35009013
Salivary ZG16B expression loss follows exocrine gland dysfunction related to oral chronic graft-versus-host disease. PMID:35005541
Downregulated ADARB1 Facilitates Cell Proliferation, Invasion and has Effect on the Immune Regulation in Ovarian Cancer. PMID:35004651
Weighted Gene Coexpression Network Analysis in Mouse Livers following Ischemia-Reperfusion and Extensive Hepatectomy. PMID:35003298
Proteogenic Dipeptides Are Characterized by Diel Fluctuations and Target of Rapamycin Complex-Signaling Dependency in the Model Plant Arabidopsis thaliana. PMID:35003157
Relating Global and Local Connectome Changes to Dementia and Targeted Gene Expression in Alzheimer's Disease. PMID:35002653
Development of Potential Prognostic Biomarkers Based on DNA Methylation-Driven Genes for Patients with Endometrial Cancer. PMID:35002309
Integrated bioinformatics and network pharmacology to identify the therapeutic target and molecular mechanisms of Huangqin decoction on ulcerative Colitis. PMID:34997010
Overexpression of SKA3 correlates with poor prognosis in female early breast cancer. PMID:34993016
HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma. PMID:34987583
Weighted Gene Correlation Network Analysis Identifies Specific Functional Modules and Genes in Esophageal Cancer. PMID:34987580
Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke. PMID:34985385
An effective drug-disease associations prediction model based on graphic representation learning over multi-biomolecular network. PMID:34983364
Screening and analysis of RNAs associated with activated memory CD4 and CD8 T cells in liver cancer. PMID:34980144
Multidimensional Dynamics of the Proteome in the Neurodegenerative and Aging Mammalian Brain. PMID:34979241
Analysis of Microarray Data from Medulloblastoma Tissue Samples. PMID:34978688
Development and Validation of a Novel Hypoxia-Related Long Noncoding RNA Model With Regard to Prognosis and Immune Features in Breast Cancer. PMID:34977036
Understanding Gene Expression and Transcriptome Profiling of COVID-19: An Initiative Towards the Mapping of Protective Immunity Genes Against SARS-CoV-2 Infection. PMID:34975833
Network Pharmacology-Based Investigation and Experimental Exploration of the Antiapoptotic Mechanism of Colchicine on Myocardial Ischemia Reperfusion Injury. PMID:34975499
Establishment of Human Pluripotent Stem Cell-Derived Skin Organoids Enabled Pathophysiological Model of SARS-CoV-2 Infection. PMID:34971128
An Robust Rank Aggregation and Least Absolute Shrinkage and Selection Operator Analysis of Novel Gene Signatures in Dilated Cardiomyopathy. PMID:34970603
Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology. PMID:34970312
Interpretable network propagation with application to expanding the repertoire of human proteins that interact with SARS-CoV-2. PMID:34966926
Network pharmacology-based strategy to investigate the active ingredients and molecular mechanisms of Scutellaria Barbata D. Don against radiation pneumonitis. PMID:34964782
Integrated Gene Expression Profiling Analysis Reveals Potential Molecular Mechanisms and Candidate Biomarkers for Early Risk Stratification and Prediction of STEMI and Post-STEMI Heart Failure Patients. PMID:34957234
Integrative genomic analysis of PPP3R1 in Alzheimer's disease: a potential biomarker for predictive, preventive, and personalized medical approach. PMID:34956428
Genomics and Prognosis Analysis of N6-Methyladenosine Regulators in Lung Adenocarcinoma. PMID:34956315
Valeriana jatamansi Jones ex Roxb. Against Post-Traumatic Stress Disorder, Network Pharmacological Analysis, and In Vivo Evaluation. PMID:34950028
MiRNA-Regulated Pathways for Hypertrophic Cardiomyopathy: Network-Based Approach to Insight into Pathogenesis. PMID:34946964
Transcriptomics Analysis of Lens from Patients with Posterior Subcapsular Congenital Cataract. PMID:34946854
Transcriptome Analysis of Neuroendocrine Regulation of Ovine Hypothalamus-Pituitary-Ovary Axis during Ovine Anestrus and the Breeding Season. PMID:34946810
Andrographolide Inhibits Lytic Reactivation of Epstein-Barr Virus by Modulating Transcription Factors in Gastric Cancer. PMID:34946164
Genome-Wide DNA Methylation Signatures Predict the Early Asymptomatic Doxorubicin-Induced Cardiotoxicity in Breast Cancer. PMID:34944912
Decreased miR-497-5p Suppresses IL-6 Induced Atrophy in Muscle Cells. PMID:34944037
Manganese-Induced Neurotoxicity through Impairment of Cross-Talk Pathways in Human Neuroblastoma Cell Line SH-SY5Y Differentiated with Retinoic Acid. PMID:34941782
Spotted Fever Group Rickettsia Trigger Species-Specific Alterations in Macrophage Proteome Signatures with Different Impacts in Host Innate Inflammatory Responses. PMID:34935429
Global Profiling of N-Glycoproteins and N-Glycans in the Diatom Phaeodactylum tricornutum. PMID:34925422
Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation. PMID:34925035
Gene prediction of aging-related diseases based on DNN and Mashup. PMID:34920719
Identification of Key Deregulated RNA-Binding Proteins in Pancreatic Cancer by Meta-Analysis and Prediction of Their Role as Modulators of Oncogenesis. PMID:34912796
Identification of homologous human miRNAs as antivirals towards COVID-19 genome. PMID:34901760
Navigating Multi-Scale Cancer Systems Biology Towards Model-Driven Clinical Oncology and Its Applications in Personalized Therapeutics. PMID:34900668
Proteomic profiling of the endogenous peptides of MRSA and MSSA. PMID:34900427
A Functional Network Model of the Metastasis Suppressor PEBP1/RKIP and Its Regulators in Breast Cancer Cells. PMID:34885208
PPM1D Is a Therapeutic Target in Childhood Neural Tumors. PMID:34885154
A Dynamic Network of Proteins Facilitate Cell Envelope Biogenesis in Gram-Negative Bacteria. PMID:34884635
CD247, a Potential T Cell-Derived Disease Severity and Prognostic Biomarker in Patients With Idiopathic Pulmonary Fibrosis. PMID:34880861
Network Pharmacology and Experimental Validation to Reveal the Pharmacological Mechanisms of Liuwei Dihuang Decoction Against Intervertebral Disc Degeneration. PMID:34880601
Identification and verification of the molecular mechanisms and prognostic values of the cadherin gene family in gastric cancer. PMID:34880371
CtBP2 interacts with TGIF to promote the progression of esophageal squamous cell cancer through the Wnt/β‑catenin pathway. PMID:34878149
The Construction and Comprehensive Analysis of a ceRNA Immunoregulatory Network and Tissue-Infiltrating Immune Cells in Atrial Fibrillation. PMID:34876841
Patient-matched analysis identifies deregulated networks in prostate cancer to guide personalized therapeutic intervention. PMID:34873462
reString: an open-source Python software to perform automatic functional enrichment retrieval, results aggregation and data visualization. PMID:34873191
Systems biology and machine learning approaches identify drug targets in diabetic nephropathy. PMID:34873190
Enhanced single-cell RNA-seq workflow reveals coronary artery disease cellular cross-talk and candidate drug targets. PMID:34871816
Developing metabolic gene signatures to predict intrahepatic cholangiocarcinoma prognosis and mining a miRNA regulatory network. PMID:34871464
Comprehensive Analysis of the Transcriptome-Wide m6A Methylation Modification Difference in Liver Fibrosis Mice by High-Throughput m6A Sequencing. PMID:34869362
Exploring the Therapeutic Mechanism of Tingli Dazao Xiefei Decoction on Heart Failure Based on Network Pharmacology and Experimental Study. PMID:34868332
Mesenchymal stromal cells mitigate liver damage after extended resection in the pig by modulating thrombospondin-1/TGF-β. PMID:34862411
Author-sourced capture of pathway knowledge in computable form using Biofactoid. PMID:34860157
The possible mechanism of Hippophae fructus oil applied in tympanic membrane repair identified based on network pharmacology and molecular docking. PMID:34859918
Identification and Validation of TYMS as a Potential Biomarker for Risk of Metastasis Development in Hepatocellular Carcinoma. PMID:34858842
Key Markers Involved in the Anticolon Cancer Response of CD8+ T Cells through the Regulation of Cholesterol Metabolism. PMID:34858500
Identifying the Effect of Ursolic Acid Against Triple-Negative Breast Cancer: Coupling Network Pharmacology With Experiments Verification. PMID:34858165
Identification of the Active Constituents and Significant Pathways of Shen-qi-Yi-zhu Decoction on Antigastric Cancer: A Network Pharmacology Research and Experimental Validation. PMID:34853601
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation. PMID:34851693
TissueNexus: a database of human tissue functional gene networks built with a large compendium of curated RNA-seq data. PMID:34850130
Identification of Unique Transcriptomic Signatures and Hub Genes Through RNA Sequencing and Integrated WGCNA and PPI Network Analysis in Nonerosive Reflux Disease. PMID:34848992
β-Sheet Richness of the Circulating Tumor-Derived Extracellular Vesicles for Noninvasive Pancreatic Cancer Screening. PMID:34846848
Temporal and sequential order of nonoverlapping gene networks unraveled in mated female Drosophila. PMID:34844981
Non-coding RNAs and related molecules associated with form-deprivation myopia in mice. PMID:34841657
Analysis of Differentially Expressed Genes That Aggravate Metabolic Diseases in Depression. PMID:34833079
Potential Prognostic Biomarkers of OSBPL Family Genes in Patients with Pancreatic Ductal Adenocarcinoma. PMID:34829830
Systemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins. PMID:34822548
Prognostic Value of SLC16A3(MCT4) in Lung Adenocarcinoma and Its Clinical Significance. PMID:34819749
Identification of miRNAs and genes for predicting Barrett's esophagus progressing to esophageal adenocarcinoma using miRNA-mRNA integrated analysis. PMID:34818353
A role of anterior cingulate cortex in the emergence of worker-parasite relationship. PMID:34815341
Transcriptome dynamics in developing testes of domestic cats and impact of age on tissue resilience to cryopreservation. PMID:34814833
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation. PMID:34809653
RETSAT Mutation Selected for Hypoxia Adaptation Inhibits Tumor Growth. PMID:34805153
RBM8A Promotes Glioblastoma Growth and Invasion Through the Notch/STAT3 Pathway. PMID:34804926
Predicting Human Protein Subcellular Locations by Using a Combination of Network and Function Features. PMID:34804131
Integrative Analysis for Elucidating Transcriptomics Landscapes of Systemic Lupus Erythematosus. PMID:34804130
Identification of key regulators in parathyroid adenoma using an integrative gene network analysis. PMID:34803267
Systematic analysis of the lysine malonylome in Sanghuangporus sanghuang. PMID:34798813
Hsa-mir-3163 and CCNB1 may be potential biomarkers and therapeutic targets for androgen receptor positive triple-negative breast cancer. PMID:34797837
TCGA database analysis of the tumor mutation burden and its clinical significance in colon cancer. PMID:34790389
Inhibition of bone morphogenetic proteins signaling suppresses metastasis melanoma: a proteomics approach. PMID:34786044
Network based analysis identifies TP53m-BRCA1/2wt-homologous recombination proficient (HRP) population with enhanced susceptibility to Vigil immunotherapy. PMID:34785763
Identification of key genes involved in recovery from spinal cord injury in adult zebrafish. PMID:34782579
Diagnostic and Prognostic Significances of SOX9 in Thymic Epithelial Tumor. PMID:34778027
Identification of Potential Novel Prognosis-Related Genes Through Transcriptome Sequencing, Bioinformatics Analysis, and Clinical Validation in Acute Myeloid Leukemia. PMID:34777462
Drug metabolism-related eight-gene signature can predict the prognosis of gastric adenocarcinoma. PMID:34773716
Identification of key genes and pathways associated with resting mast cells in meningioma. PMID:34772393
An RNA-Seq-Based Framework for Characterizing Canine Prostate Cancer and Prioritizing Clinically Relevant Biomarker Candidate Genes. PMID:34768937
Revealing the Mechanism of Friedelin in the Treatment of Ulcerative Colitis Based on Network Pharmacology and Experimental Verification. PMID:34765000
CicerSpTEdb: A web-based database for high-resolution genome-wide identification of transposable elements in Cicer species. PMID:34762703
Alternative Splicing-Based Differences Between Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma: Genes, Immune Microenvironment, and Survival Prognosis. PMID:34760694
Integrative analysis of Iso-Seq and RNA-seq data reveals transcriptome complexity and differentially expressed transcripts in sheep tail fat. PMID:34760406
Down-regulation of EPB41L4A-AS1 mediated the brain aging and neurodegenerative diseases via damaging synthesis of NAD+ and ATP. PMID:34758883
Role of adipocyte Na,K-ATPase oxidant amplification loop in cognitive decline and neurodegeneration. PMID:34755095
Genome-wide approaches delineate the additive, epistatic, and pleiotropic nature of variants controlling fatty acid composition in peanut (Arachis hypogaea L.). PMID:34751378
The Mechanism Exploration of Follicular Fluids on Granulose Cell Apoptosis in Endometriosis-Associated Infertility. PMID:34746304
Study on the Mechanism of Liuwei Dihuang Pills in Treating Parkinson's Disease Based on Network Pharmacology. PMID:34746302
Identification of Gene-Set Signature in Early-Stage Hepatocellular Carcinoma and Relevant Immune Characteristics. PMID:34745960
A Transcriptome Analysis Revealing the New Insight of Green Light on Tomato Plant Growth and Drought Stress Tolerance. PMID:34745154
Identifying stress responsive genes using overlapping communities in co-expression networks. PMID:34743699
MiR-16-5p suppresses breast cancer proliferation by targeting ANLN. PMID:34743685
The Identification of Blood Biomarkers of Chronic Neuropathic Pain by Comparative Transcriptomics. PMID:34741226
Significance of TEAD Family in Diagnosis, Prognosis and Immune Response for Ovarian Serous Carcinoma. PMID:34737608
Integrated miRNA-mRNA Expression Profiles Revealing Key Molecules in Ovarian Cancer Based on Bioinformatics Analysis. PMID:34734085
Identification of the distinctive role of DPT in dilated cardiomyopathy: a study based on bulk and single-cell transcriptomic analysis. PMID:34733953
Comparison of critical biomarkers in 2 erectile dysfunction models based on GEO and NOS-cGMP-PDE5 pathway. PMID:34731136
Differential proteome profile, biological pathways, and network relationships of osteogenic proteins in calcified human aortic valves. PMID:34727208
Toward Integrated Multi-Omics Intervention: Rice Trait Improvement and Stress Management. PMID:34721467
Efficient induction and sustenance of pluripotent stem cells from bovine somatic cells. PMID:34719702
Identification of hub genes associated with cognition in the hippocampus of Alzheimer's Disease. PMID:34719328
Screening of characteristic genes in ulcerative colitis by integrating gene expression profiles. PMID:34717557
Exploration of the anti-insomnia mechanism of Ganoderma by central-peripheral multi-level interaction network analysis. PMID:34715778
Oncogene-mediated metabolic gene signature predicts breast cancer outcome. PMID:34711841
Development and validation of genomic and epigenomic signatures associated with tumor immune microenvironment in hepatoblastoma. PMID:34711185
Effects and Components of Herb Pair Huanglian-Banxia on Diabetic Gastroparesis by Network Pharmacology. PMID:34708128
Analysing a Novel RNA-Binding-Protein-Related Prognostic Signature Highly Expressed in Breast Cancer. PMID:34707800
In-depth proteomic profiling captures subtype-specific features of craniopharyngiomas. PMID:34707096
Ferroptosis-related gene AKR1C1 predicts the prognosis of non-small cell lung cancer. PMID:34702254
Patient Heterogeneity in Acute Myeloid Leukemia: Leukemic Cell Communication by Release of Soluble Mediators and Its Effects on Mesenchymal Stem Cells. PMID:34698165
Entropy-Based Graph Clustering of PPI Networks for Predicting Overlapping Functional Modules of Proteins. PMID:34681995
Mining Fiskeby III and Mandarin (Ottawa) Expression Profiles to Understand Iron Stress Tolerant Responses in Soybean. PMID:34681702
Expression of Cytokine-Coding Genes BMP8B, LEFTY1 and INSL5 Could Distinguish between Ulcerative Colitis and Crohn's Disease. PMID:34680872
Expression Profiles and Prognostic Value of FABPs in Colorectal Adenocarcinomas. PMID:34680577
In silico Approach for Validating and Unveiling New Applications for Prognostic Biomarkers of Endometrial Cancer. PMID:34680205
Development and Validation of a Prognostic Model of RNA-Binding Proteins in Colon Adenocarcinoma: A Study Based on TCGA and GEO Databases. PMID:34675667
Comprehensive Analysis of Key mRNAs and lncRNAs in Osteosarcoma Response to Preoperative Chemotherapy with Prognostic Values. PMID:34671904
A New Stemness-Related Prognostic Model for Predicting the Prognosis in Pancreatic Ductal Adenocarcinoma. PMID:34671679
Microarray analysis of hub genes and pathways in damaged cartilage tissues of knee. PMID:34664844
Investigation on the mechanisms of guiqi huoxue capsule for treating cervical spondylosis based on network pharmacology and molecular docking. PMID:34664825
A global cancer data integrator reveals principles of synthetic lethality, sex disparity and immunotherapy. PMID:34663427
Expression of Microtubule-Associated Proteins in Relation to Prognosis and Efficacy of Immunotherapy in Non-Small Cell Lung Cancer. PMID:34660263
Investigation of anti-osteoporosis mechanisms of Rehmanniae Radix Preparata based on network pharmacology and experimental verification. PMID:34649566
An Advanced Systems Pharmacology Strategy Reveals AKR1B1, MMP2, PTGER3 as Key Genes in the Competing Endogenous RNA Network of Compound Kushen Injection Treating Gastric Carcinoma by Integrated Bioinformatics and Experimental Verification. PMID:34646828
Serum Fetuin-B Levels Are Elevated in Women with Metabolic Syndrome and Associated with Increased Oxidative Stress. PMID:34646426
GreeningDB: A Database of Host-Pathogen Protein-Protein Interactions and Annotation Features of the Bacteria Causing Huanglongbing HLB Disease. PMID:34639237
Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile. PMID:34637780
A new prognostic risk model based on autophagy-related genes in kidney renal clear cell carcinoma. PMID:34636718
MicroRNAs in oral fluids (saliva and gingival crevicular fluid) as biomarkers in orthodontics: systematic review and integrated bioinformatic analysis. PMID:34632546
Getting to know each other: PPIMem, a novel approach for predicting transmembrane protein-protein complexes. PMID:34630938
Identification of Unique Peptides for SARS-CoV-2 Diagnostics and Vaccine Development by an In Silico Proteomics Approach. PMID:34630400
Component of oligomeric Golgi complex 1 deficiency leads to hypoglycemia: a case report and literature review. PMID:34625039
Protein-protein interaction prediction based on ordinal regression and recurrent convolutional neural networks. PMID:34625020
Effects of Bacille Calmette Guerin (BCG) vaccination during COVID-19 infection. PMID:34624759
A protocol for dynamic model calibration. PMID:34619769
Weighted Gene Co-Expression Network Analysis Identifies ANGPTL4 as a Key Regulator in Diabetic Cardiomyopathy via FAK/SIRT3/ROS Pathway in Cardiomyocyte. PMID:34616362
Microglia Mediate the Occurrence and Development of Alzheimer's Disease Through Ligand-Receptor Axis Communication. PMID:34616287
A seven-gene signature and the C-C motif chemokine receptor family genes are the sarcoma-related immune genes. PMID:34605725
Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth. PMID:34604224
Genome-Wide Identification and Analysis of the NF-Y Gene Family in Potato (Solanum tuberosum L.). PMID:34603398
Comprehensive analysis of prognostic immune-related genes in the tumor microenvironment of hepatocellular carcinoma (HCC). PMID:34596136
Identification of hub genes and candidate drugs in hepatocellular carcinoma by integrated bioinformatics analysis. PMID:34596112
A Network Pharmacology Study on the Molecular Mechanism of Protocatechualdehyde in the Treatment of Diabetic Cataract. PMID:34594100
A protein interaction landscape of breast cancer. PMID:34591612
Myrtenal and β-caryophyllene oxide screened from Liquidambaris Fructus suppress NLRP3 inflammasome components in rheumatoid arthritis. PMID:34583676
Integrative proteome analysis implicates aberrant RNA splicing in impaired developmental potential of aged mouse oocytes. PMID:34582091
Identification of Potential Core Genes in Parkinson's Disease Using Bioinformatics Analysis. PMID:34580608
Deciphering the Dynamics of Signaling Cascades and Virulence Factors of B. cinerea during Tomato Cell Wall Degradation. PMID:34576732
Synergistic Interactions of Cannabidiol with Chemotherapeutic Drugs in MCF7 Cells: Mode of Interaction and Proteomics Analysis of Mechanisms. PMID:34576262
Prognostic Impact and Functional Annotations of KIF11 and KIF14 Expression in Patients with Colorectal Cancer. PMID:34575892
Genome-Wide Identification and Transcriptional Expression Profiles of Transcription Factor WRKY in Common Walnut (Juglans regia L.). PMID:34573426
NRF2 Mediates Therapeutic Resistance to Chemoradiation in Colorectal Cancer through a Metabolic Switch. PMID:34573012
HMGB1 Protein Interactions in Prostate and Ovary Cancer Models Reveal Links to RNA Processing and Ribosome Biogenesis through NuRD, THOC and Septin Complexes. PMID:34572914
Platelet miRNA Biosignature Discriminates between Dementia with Lewy Bodies and Alzheimer's Disease. PMID:34572457
Modelling Nonalcoholic Steatohepatitis In Vivo-A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model. PMID:34572384
Integrated Analysis of the Expression Characteristics, Prognostic Value, and Immune Characteristics of PPARG in Breast Cancer. PMID:34567087
Identification of Potential Prognostic Biomarker for Predicting Survival in Multiple Myeloma Using Bioinformatics Analysis and Experiments. PMID:34567073
Integrating Network Pharmacology and RT-qPCR Analysis to Investigate the Mechanisms Underlying ZeXie Decoction-Mediated Treatment of Non-alcoholic Fatty Liver Disease. PMID:34566646
Glycolysis related gene expression signature in predicting prognosis of laryngeal squamous cell carcinoma. PMID:34565301
Targeting the VCP-binding motif of ataxin-3 improves phenotypes in Drosophila models of Spinocerebellar Ataxia Type 3. PMID:34563642
HIV-Proteins-Associated CNS Neurotoxicity, Their Mediators, and Alternative Treatments. PMID:34562223
Transcriptional and cellular signatures of cortical morphometric remodelling in chronic pain. PMID:34561394
A Network Pharmacology and Molecular Docking Strategy to Explore Potential Targets and Mechanisms Underlying the Effect of Curcumin on Osteonecrosis of the Femoral Head in Systemic Lupus Erythematosus. PMID:34557547
Identification of Key Candidate Genes and Chemical Perturbagens in Diabetic Kidney Disease Using Integrated Bioinformatics Analysis. PMID:34557161
The Human Innate Immune Protein Calprotectin Elicits a Multimetal Starvation Response in Pseudomonas aeruginosa. PMID:34549997
Classification of protein domains based on their three-dimensional shapes (CPD3DS). PMID:34541344
Comprehensive Analysis of HDAC Family Identifies HDAC1 as a Prognostic and Immune Infiltration Indicator and HDAC1-Related Signature for Prognosis in Glioma. PMID:34540896
Identification of Key Genes Associated With the Process of Hepatitis B Inflammation and Cancer Transformation by Integrated Bioinformatics Analysis. PMID:34539726
Comprehensive Analysis of circRNA Expression Profiles During Cervical Carcinogenesis. PMID:34532284
Multidimensional Analyses of Tumor Immune Microenvironment Reveal the Possible Rationality of Immunotherapy and Identify High Immunotherapy Response Subtypes for Renal Papillary Cell Carcinoma. PMID:34531849
Identification of Novel Gene Signatures using Next-Generation Sequencing Data from COVID-19 Infection Models: Focus on Neuro-COVID and Potential Therapeutics. PMID:34531741
Identifying digenic disease genes via machine learning in the Undiagnosed Diseases Network. PMID:34529933
Integrated Phytochemical Analysis Based on UPLC-MS/MS and Network Pharmacology Approaches to Explore the Effect of Odontites vulgaris Moench on Rheumatoid Arthritis. PMID:34526896
DNA methylation and gene expression profiles to identify childhood atopic asthma associated genes. PMID:34525985
Integrated analysis of the molecular mechanisms in idiopathic pulmonary fibrosis. PMID:34522168
An Integrated Analysis of Network Pharmacology and Experimental Validation to Reveal the Mechanism of Chinese Medicine Formula Naotaifang in Treating Cerebral Ischemia-Reperfusion Injury. PMID:34522084
A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids. PMID:34518665
A comprehensive analysis of different gene classes in pancreatic cancer: SIGLEC15 may be a promising immunotherapeutic target. PMID:34515878
Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer. PMID:34514028
Dysregulated Circulating Apoptosis- and Autophagy-Related lncRNAs as Diagnostic Markers in Coronary Artery Disease. PMID:34513991
Protein Arginine Methyltransferase 5 Functions via Interacting Proteins. PMID:34513846
Protein function prediction with gene ontology: from traditional to deep learning models. PMID:34513334
ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 Susceptibility. PMID:34512723
Comprehensive Analysis of the Expression and Prognosis for Laminin Genes in Ovarian Cancer. PMID:34512203
Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B. PMID:34512150
Prioritizing Susceptible Genes for Thyroid Cancer Based on Gene Interaction Network. PMID:34497810
Comprehensive Analysis of YTH Domain Family in Lung Adenocarcinoma: Expression Profile, Association with Prognostic Value, and Immune Infiltration. PMID:34497675
Gene Expression Analysis Reveals Key Genes and Signalings Associated with the Prognosis of Prostate Cancer. PMID:34497666
Establishment of an Immune-Related Gene Signature for Risk Stratification for Patients with Glioma. PMID:34497663
The 'un-shrunk' partial correlation in Gaussian graphical models. PMID:34493207
Identification of potential genes associated with ALDH1A1 overexpression and cyclophosphamide resistance in chronic myelogenous leukemia using network analysis. PMID:34491453
Identification of Potential Biomarkers Associated with Acute Myocardial Infarction by Weighted Gene Coexpression Network Analysis. PMID:34490057
Comprehensive analysis of LASS6 expression and prognostic value in ovarian cancer. PMID:34488809
TMEA, a Polyphenol in Sanguisorba officinalis, Promotes Thrombocytopoiesis by Upregulating PI3K/Akt Signaling. PMID:34485295
Screening and Identification of Key Biomarkers of Gastric Cancer: Three Genes Jointly Predict Gastric Cancer. PMID:34485109
Water-Soluble Humic Materials Modulating Metabolism and Triggering Stress Defense in Sinorhizobium fredii. PMID:34479412
Genome-wide analysis and characterization of GRAS family in switchgrass. PMID:34477486
Identification of the similarly expressed genes in patients with polycystic ovary syndrome and transsexuals. PMID:34477128
A prelude to the proximity interaction mapping of CXXC5. PMID:34475492
Prospects and challenges of cancer systems medicine: from genes to disease networks. PMID:34471925
Full-length isoform transcriptome of the developing human brain provides further insights into autism. PMID:34469739
Identification of the Key Genes of Autism Spectrum Disorder Through Protein-Protein Interaction Network. PMID:34466502
Breast Cancer Interaction Network Concept from Mostly Related Components. PMID:34466490
Compound-Protein Interaction Analysis in Condition Following Cardiac Arrest. PMID:34466450
Comparative Bioinformatics Characteristic of Bladder Cancer Stage 2 from Stage 4 Expression Profile: A Network-Based Study. PMID:34466446
Comparative proteomic investigation of multiple methicillin-resistant Staphylococcus aureus strains generated through adaptive laboratory evolution. PMID:34458699
The Fibrosis-Targeted Collagen/Integrins Gene Profile Predicts Risk of Metastasis in Pulmonary Neuroendocrine Neoplasms. PMID:34458147
Proteomic analysis of machine perfusion solution from brain dead donor kidneys reveals that elevated complement, cytoskeleton and lipid metabolism proteins are associated with 1-year outcome. PMID:34448265
Promising Anticancer Activity of [Bis(1,8-quinolato)palladium (II)] Alone and in Combination. PMID:34445176
A Novel Approach for the Discovery of Biomarkers of Radiotherapy Response in Breast Cancer. PMID:34442440
Proteomic Analysis Reveals Key Proteins in Extracellular Vesicles Cargo Associated with Idiopathic Pulmonary Fibrosis In Vitro. PMID:34440261
What Antarctic Plants Can Tell Us about Climate Changes: Temperature as a Driver for Metabolic Reprogramming. PMID:34439761
In Vitro and In Silico Toxicological Properties of Natural Antioxidant Therapeutic Agent Azimatetracantha. LAM. PMID:34439555
Tear Proteomics in Keratoconus: A Quantitative SWATH-MS Analysis. PMID:34431975
The mechanisms of Chuanxiong Rhizoma in treating spinal cord injury based on network pharmacology and experimental verification. PMID:34430586
Potential Arabidopsis thaliana glucosinolate genes identified from the co-expression modules using graph clustering approach. PMID:34430080
Decreased Spp1 Expression in Acute Myocardial Infarction after Ischemia and Reperfusion Injury. PMID:34426769
The Integrity of the HMR complex is necessary for centromeric binding and reproductive isolation in Drosophila. PMID:34424906
Identification of JAK2 and FOXM1 expression as novel candidate biomarkers for predicting the benefit of immunotherapy in lung squamous cell carcinoma. PMID:34422993
Decreased Expression of PACSIN1 in Brain Glioma Samples Predicts Poor Prognosis. PMID:34422904
Systematic Analysis Identifies a Specific RNA-Binding Protein-Related Gene Model for Prognostication and Risk-Adjustment in HBV-Related Hepatocellular Carcinoma. PMID:34422009
Prediction of Genetic Factors of Hyperthyroidism Based on Gene Interaction Network. PMID:34409035
High Expression of RhoF Predicts Worse Overall Survival: A Potential Therapeutic Target for non-M3 Acute Myeloid Leukemia. PMID:34405015
Integrated bioinformatics analysis of differentially expressed genes and immune cell infiltration characteristics in Esophageal Squamous cell carcinoma. PMID:34404882
ELMO1 signaling is a promoter of osteoclast function and bone loss. PMID:34404802
Evaluating of Gene Expression Alteration after Garlic Consumption, Analyzing through Bioinformatics Approach. PMID:34400942
Integrated Chromatin Accessibility and Transcriptome Landscapes of Doxorubicin-Resistant Breast Cancer Cells. PMID:34395436
Expanding the potential genes of inborn errors of immunity through protein interactions. PMID:34391382
Employing bioinformatics analysis to identify hub genes and microRNAs involved in colorectal cancer. PMID:34390411
Integrated Bioinformatics Analysis of DNA Methylation Biomarkers in Thyroid Cancer Based on TCGA Database. PMID:34387764
Network Pharmacology and Experimental Evidence: PI3K/AKT Signaling Pathway is Involved in the Antidepressive Roles of Chaihu Shugan San. PMID:34385814
Identification and Quantification of Glutathionylated Cysteines under Ischemic Stress. PMID:34382403
Protein Integrated Network Analysis to Reveal Potential Drug Targets Against Extended Drug-Resistant Mycobacterium tuberculosis XDR1219. PMID:34382159
Investigating the Mechanism of Scutellariae barbata Herba in the Treatment of Colorectal Cancer by Network Pharmacology and Molecular Docking. PMID:34381520
Comprehensive Analysis of the Expression and Prognostic Value of SPINT1/2 in Breast Carcinoma. PMID:34381422
Reciprocal interplay between asporin and decorin: Implications in gastric cancer prognosis. PMID:34379688
SERPINH1, Targeted by miR-29b, Modulated Proliferation and Migration of Human Retinal Endothelial Cells Under High Glucose Conditions. PMID:34377003
Systematic Bioinformatic Analyses of Nutrigenomic Modifications by Polyphenols Associated with Cardiometabolic Health in Humans-Evidence from Targeted Nutrigenomic Studies. PMID:34371836
PPIDomainMiner: Inferring domain-domain interactions from multiple sources of protein-protein interactions. PMID:34370723
Multi-Level Analyses of Genome-Wide Association Study to Reveal Significant Risk Genes and Pathways in Neuromyelitis Optica Spectrum Disorder. PMID:34367251
Molecular Characterization and Elucidation of Pathways to Identify Novel Therapeutic Targets in Pulmonary Arterial Hypertension. PMID:34366885
Potential stress tolerance roles of barley germins and GLPs. PMID:34363524
Metabolomic Identification of Anticancer Metabolites of Australian Propolis and Proteomic Elucidation of Its Synergistic Mechanisms with Doxorubicin in the MCF7 Cells. PMID:34360606
Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast. PMID:34358317
Efficacy of signal peptide predictors in identifying signal peptides in the experimental secretome of Picrophilous torridus, a thermoacidophilic archaeon. PMID:34358261
Pan-cancer chromatin analysis of the human vtRNA genes uncovers their association with cancer biology. PMID:34354812
An apocrine mechanism delivers a fully immunocompetent exocrine secretion. PMID:34354130
Extract From Tetrastigma hemsleyanum Leaf Alleviates Pseudomonas aeruginosa Lung Infection: Network Pharmacology Analysis and Experimental Evidence. PMID:34349638
TRAIP modulates the IGFBP3/AKT pathway to enhance the invasion and proliferation of osteosarcoma by promoting KANK1 degradation. PMID:34349117
Identification of potential biomarkers in dengue via integrated bioinformatic analysis. PMID:34347790
Ubiquitination-Related miRNA-mRNA Interaction Is a Potential Mechanism in the Progression of Retinoblastoma. PMID:34347012
Association of MACC1 expression with lymphatic metastasis in colorectal cancer: A nested case-control study. PMID:34343214
A CpG island promoter drives the CXXC5 gene expression. PMID:34341443
Identifying molecular insight of synergistic complexities for SARS-CoV-2 infection with pre-existing type 2 diabetes. PMID:34340124
Identification of Key Biomarkers and Immune Infiltration in Systemic Juvenile Idiopathic Arthritis by Integrated Bioinformatic Analysis. PMID:34336925
Prognostic Value of a Novel Signature With Nine Hepatitis C Virus-Induced Genes in Hepatic Cancer by Mining GEO and TCGA Databases. PMID:34336819
Integrative Functional Genomic Analysis of Molecular Signatures and Mechanistic Pathways in the Cell Cycle Underlying Alzheimer's Disease. PMID:34336099
Exploring the Mechanism of Scutellaria baicalensis Georgi Efficacy against Oral Squamous Cell Carcinoma Based on Network Pharmacology and Molecular Docking Analysis. PMID:34335829
LGALS3BP: A Potential Plasma Biomarker Associated with Diagnosis and Prognosis in Patients with Sepsis. PMID:34335032
Aurora kinase A (AURKA) promotes the progression and imatinib resistance of advanced gastrointestinal stromal tumors. PMID:34332577
Genetic alterations and functional networks of m6A RNA methylation regulators in pancreatic cancer based on data mining. PMID:34330301
Network Pharmacology/Metabolomics-Based Validation of AMPK and PI3K/AKT Signaling Pathway as a Central Role of Shengqi Fuzheng Injection Regulation of Mitochondrial Dysfunction in Cancer-Related Fatigue. PMID:34326918
Pan-cancer analysis of m5C regulator genes reveals consistent epigenetic landscape changes in multiple cancers. PMID:34325709
In vitro and in silico analysis reveals antifungal activity and potential targets of curcumin on Paracoccidioides spp. PMID:34324170
Development of a gene signature associated with iron metabolism in lung adenocarcinoma. PMID:34323652
Network pharmacology to investigate the pharmacological mechanisms of muscone in Xingnaojing injections for the treatment of severe traumatic brain injury. PMID:34322321
Genome wide analysis implicates upregulation of proteasome pathway in major depressive disorder. PMID:34321460
The Mechanism of Xiaoyao San in the Treatment of Ovarian Cancer by Network Pharmacology and the Effect of Stigmasterol on the PI3K/Akt Pathway. PMID:34306252
Study on HOXBs of Clear Cell Renal Cell Carcinoma and Detection of New Molecular Target. PMID:34306077
A neural network-based method for polypharmacy side effects prediction. PMID:34303360
KiRNet: Kinase-centered network propagation of pharmacological screen results. PMID:34296206
Integrative Identification of Crucial Genes Associated With Plant Hormone-Mediated Bud Dormancy in Prunus mume. PMID:34295354
Integrating ensemble systems biology feature selection and bimodal deep neural network for breast cancer prognosis prediction. PMID:34290286
Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2. PMID:34289357
Pathogen-induced inflammation is attenuated by the iminosugar MON-DNJ via modulation of the unfolded protein response. PMID:34287854
Exploration of the molecular targets and mechanisms of suxiao xintong dropping pills for myocardial infarction by network pharmacology method. PMID:34286341
Correlation Imputation in Single cell RNA-seq using Auxiliary Information and Ensemble Learning. PMID:34278382
Comparative Analysis of Skeletal Muscle DNA Methylation and Transcriptome of the Chicken Embryo at Different Developmental Stages. PMID:34276416
Decoding the molecular mechanism of parthenocarpy in Musa spp. through protein-protein interaction network. PMID:34272422
An ancestral recombination graph of human, Neanderthal, and Denisovan genomes. PMID:34272242
Identification of hub genes in rheumatoid arthritis through an integrated bioinformatics approach. PMID:34271942
Geometry and symmetry in biochemical reaction systems. PMID:34268705
Identification and validation of an immune-related prognostic signature and key gene in papillary thyroid carcinoma. PMID:34266418
Identification of Gene Loci That Overlap Between Mental Disorders and Poor Prognosis of Cancers. PMID:34262492
The Study on the Mechanism of Hugan Tablets in Treating Drug-Induced Liver Injury Induced by Atorvastatin. PMID:34262454
Identification of Autophagy-Related Genes in the Progression from Non-Alcoholic Fatty Liver to Non-Alcoholic Steatohepatitis. PMID:34262330
FSTL3 is a Prognostic Biomarker in Gastric Cancer and is Correlated with M2 Macrophage Infiltration. PMID:34262295
Sclerotinia sclerotiorum Response to Long Exposure to Glucosinolate Hydrolysis Products by Transcriptomic Approach. PMID:34259546
Therapeutic Targets and Mechanism of Xingpi Jieyu Decoction in Depression: A Network Pharmacology Study. PMID:34257681
Learning epistatic gene interactions from perturbation screens. PMID:34255784
Solute carrier transporter superfamily member SLC16A1 is a potential prognostic biomarker and associated with immune infiltration in skin cutaneous melanoma. PMID:34254872
Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease. PMID:34253728
Immunotherapy-based targeting of MSLN+ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis. PMID:34253615
Novel immune-related signature for risk stratification and prognosis in prostatic adenocarcinoma. PMID:34252262
Biological Network Mining. PMID:34251623
An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. PMID:34251175
Bioinformatics analysis of enzymes involved in cysteine biosynthesis: first evidence for the formation of cysteine synthase complex in cyanobacteria. PMID:34249595
Bioinformatics analysis of the role of CXC ligands in the microenvironment of head and neck tumor. PMID:34247149
The Research on the Treatment of Metastatic Skin Cutaneous Melanoma by Huanglian Jiedu Decoction Based on the Analysis of Immune Infiltration Analysis. PMID:34239596
Thioredoxin reductase is a major regulator of metabolism in leukemia cells. PMID:34239044
Inference of kinase-signaling networks in human myeloid cell line models by Phosphoproteomics using kinase activity enrichment analysis (KAEA). PMID:34238254
Computational analysis for identification of early diagnostic biomarkers and prognostic biomarkers of liver cancer based on GEO and TCGA databases and studies on pathways and biological functions affecting the survival time of liver cancer. PMID:34238253
Databases for Protein-Protein Interactions. PMID:34236665
Comprehensive Bioinformatics Analysis of mRNA Expression Profiles and Identification of a miRNA-mRNA Network Associated with the Pathogenesis of Low-Grade Gliomas. PMID:34234557
Carbonic anhydrase IX and hypoxia-inducible factor 1 attenuate cardiac dysfunction after myocardial infarction. PMID:34231059
Integration of transcriptomic data identifies key hallmark genes in hypertrophic cardiomyopathy. PMID:34225646
Transcriptomics unravels molecular players shaping dorsal lip hypertrophy in the vacuum cleaner cichlid, Gnathochromis permaxillaris. PMID:34225643
HTR2B and SLC5A3 Are Specific Markers in Age-Related Osteoarthritis and Involved in Apoptosis and Inflammation of Osteoarthritis Synovial Cells. PMID:34222340
The Clinical Efficiency and the Mechanism of Sanzi Yangqin Decoction for Chronic Obstructive Pulmonary Disease. PMID:34221077
Investigation of the Mechanisms of Chuankezhi Injection in the Treatment of Asthma Based on the Network Pharmacology Approach. PMID:34221070
The underlying molecular mechanism and drugs for treatment in adrenal cortical carcinoma. PMID:34220331
Bacterial Protein Interaction Networks: Connectivity is Ruled by Gene Conservation, Essentiality and Function. PMID:34220298
Network Pharmacology-Based Approach to Investigate the Molecular Targets of Rhubarb for Treating Cancer. PMID:34211578
A Computational-Based Drug Repurposing Method Targeting SARS-CoV-2 and its Neurological Manifestations Genes and Signaling Pathways. PMID:34211268
Repurposing FDA approved drugs as radiosensitizers for treating hypoxic prostate cancer. PMID:34210300
Proteomic Analysis of Liver from Finishing Beef Cattle Supplemented with a Rumen-Protected B-Vitamin Blend and Hydroxy Trace Minerals. PMID:34209530
Loss of Wnt16 Leads to Skeletal Deformities and Downregulation of Bone Developmental Pathway in Zebrafish. PMID:34206401
Proteomics Analysis of Andrographolide-Induced Apoptosis via the Regulation of Tumor Suppressor p53 Proteolysis in Cervical Cancer-Derived Human Papillomavirus 16-Positive Cell Lines. PMID:34202736
Mining Proteome Research Reports: A Bird's Eye View. PMID:34200663
m5C RNA Methylation Regulators Predict Prognosis and Regulate the Immune Microenvironment in Lung Squamous Cell Carcinoma. PMID:34195072
Identification of the genetic basis of sporadic polydactyly in China by targeted sequencing. PMID:34194672
The Evaluation and Validation of Blood-Derived Novel Biomarkers for Precise and Rapid Diagnosis of Tuberculosis in Areas With High-TB Burden. PMID:34194403
Comprehensive Proteomics Profiling Reveals Circulating Biomarkers of Hypertrophic Cardiomyopathy. PMID:34192899
Comprehensive analysis of DNA methylation and gene expression profiles in gestational diabetes mellitus. PMID:34190178
Identification of genes modulated by interferon gamma in breast cancer cells. PMID:34189281
The m6A landscape of polyadenylated nuclear (PAN) RNA and its related methylome in the context of KSHV replication. PMID:34187903
Identification of hub genes associated with prognosis, diagnosis, immune infiltration and therapeutic drug in liver cancer by integrated analysis. PMID:34187556
Antifungal mechanism of Bacillus amyloliquefaciens strain GKT04 against Fusarium wilt revealed using genomic and transcriptomic analyses. PMID:34180606
Multi-Omics Approaches in Immunological Research. PMID:34177908
Identification of Key Genes and Pathways in Gefitinib-Resistant Lung Adenocarcinoma using Bioinformatics Analysis. PMID:34177255
Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity. PMID:34169837
Proteomics Analysis Reveals Bacterial Antibiotics Resistance Mechanism Mediated by ahslyA Against Enoxacin in Aeromonas hydrophila. PMID:34168639
The human nucleoporin Tpr protects cells from RNA-mediated replication stress. PMID:34168151
The mechanisms of celastrol in treating papillary thyroid carcinoma based on network pharmacology and experiment verification. PMID:34164500
Bioinformatics Analysis Identifies Potential Ferroptosis Key Genes in the Pathogenesis of Intracerebral Hemorrhage. PMID:34163322
Proteomic differences in the hippocampus and cortex of epilepsy brain tissue. PMID:34159317
Multilevel systems biology analysis of lung transcriptomics data identifies key miRNAs and potential miRNA target genes for SARS-CoV-2 infection. PMID:34157472
Tyr-Asp inhibition of glyceraldehyde 3-phosphate dehydrogenase affects plant redox metabolism. PMID:34156108
A network pharmacology approach to determine the underlying mechanisms of action of Yishen Tongluo formula for the treatment of oligoasthenozoospermia. PMID:34153045
Identification of significant genes and therapeutic agents for breast cancer by integrated genomics. PMID:34151730
Integrated Analysis of Cell Cycle-Related and Immunity-Related Biomarker Signatures to Improve the Prognosis Prediction of Lung Adenocarcinoma. PMID:34150632
Identification of a Competing Endogenous RNA Network Related to Immune Signature in Lung Adenocarcinoma. PMID:34149807
Identification and validation of inferior prognostic genes associated with immune signatures and chemotherapy outcome in acute myeloid leukemia. PMID:34148032
Integrating genome-wide association and transcriptome prediction model identifies novel target genes for osteoporosis. PMID:34142171
Arhgef2 regulates neural differentiation in the cerebral cortex through mRNA m6A-methylation of Npdc1 and Cend1. PMID:34142067
Involvement of eNAMPT/TLR4 signaling in murine radiation pneumonitis: protection by eNAMPT neutralization. PMID:34139379
A structural deep network embedding model for predicting associations between miRNA and disease based on molecular association network. PMID:34135401
Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity. PMID:34134991
Transcriptomics of type 2 diabetic and healthy human neutrophils. PMID:34134627
Bioinformatic profiling identifies prognosis-related genes in the immune microenvironment of endometrial carcinoma. PMID:34131259
Exploration and validation of hub genes and pathways in the progression of hypoplastic left heart syndrome via weighted gene co-expression network analysis. PMID:34130651
Network-based transcriptomic analysis identifies the genetic effect of COVID-19 to chronic kidney disease patients: A bioinformatics approach. PMID:34127904
Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes. PMID:34127860
Identification of novel hub genes associated with gastric cancer using integrated bioinformatics analysis. PMID:34126961
DGLinker: flexible knowledge-graph prediction of disease-gene associations. PMID:34125897
A novel algorithm for finding top-k weighted overlapping densest connected subgraphs in dual networks. PMID:34124340
PD-1 Coexpression Gene Analysis and the Regulatory Network in Endometrial Cancer Based on Bioinformatics Analysis. PMID:34124265
Altered Genes and Biological Functions in Response to Severe Burns. PMID:34124262
Identification of an m6A-Related lncRNA Signature for Predicting the Prognosis in Patients With Kidney Renal Clear Cell Carcinoma. PMID:34123820
Cannabidiol Displays Proteomic Similarities to Antipsychotics in Cuprizone-Exposed Human Oligodendrocytic Cell Line MO3.13. PMID:34122009
Revealing the Modular Similarities and Differences Among Alzheimer's Disease, Vascular Dementia, and Parkinson's Disease in Genomic Networks. PMID:34117614
Integrated bioinformatics analysis and screening of hub genes in papillary thyroid carcinoma. PMID:34115774
Identification of potential diagnostic biomarkers in MMPs for pancreatic carcinoma. PMID:34114996
The paeonol target gene autophagy-related 5 has a potential therapeutic value in psoriasis treatment. PMID:34113484
New Insights Into Lignification via Network and Multi-Omics Analyses of Arogenate Dehydratase Knock-Out Mutants in Arabidopsis thaliana. PMID:34113365
Identification of Susceptible Genes for Chronic Obstructive Pulmonary Disease with Lung Adenocarcinoma by Weighted Gene Co-Expression Network Analysis. PMID:34113128
Differential methylation of G-protein coupled receptor signaling genes in gastrointestinal neuroendocrine tumors. PMID:34112938
Glycoproteomics identifies HOMER3 as a potentially targetable biomarker triggered by hypoxia and glucose deprivation in bladder cancer. PMID:34108014
Levetiracetam Treatment Normalizes Levels of Presynaptic Endocytosis Machinery and Restores Nonamyloidogenic APP Processing in App Knock-in Mice. PMID:34106705
Identification of the hub genes and prognostic indicators of gastric cancer and correlation of indicators with tumor-infiltrating immune cell levels. PMID:34093807
Construction of Condition-Specific Gene Regulatory Network Using Kernel Canonical Correlation Analysis. PMID:34093651
Differentially Expressed Genes and Enriched Signaling Pathways in the Adipose Tissue of Obese People. PMID:34093637
Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity. PMID:34085697
Molecular mechanisms of fat deposition: IL-6 is a hub gene in fat lipolysis, comparing thin-tailed with fat-tailed sheep breeds. PMID:34084904
GCSENet: A GCN, CNN and SENet ensemble model for microRNA-disease association prediction. PMID:34081706
Immune-related gene expression signatures in colorectal cancer. PMID:34079596
Expression profiles and prognostic values of BolA family members in ovarian cancer. PMID:34078439
Tripartite Separation of Glomerular Cell Types and Proteomes from Reporter-Free Mice. PMID:34074698
Proteomic Comparison of Bone Marrow Derived Osteoblasts and Mesenchymal Stem Cells. PMID:34073480
Epithelial-Mesenchymal Transition Gene Signature Related to Prognostic in Colon Adenocarcinoma. PMID:34073426
Comparative Proteomic Profiling: Cellular Metabolisms Are Mainly Affected in Senecavirus A-Inoculated Cells at an Early Stage of Infection. PMID:34072643
Heparin-Binding Protein 17/Fibroblast Growth Factor-Binding Protein-1 Knockout Inhibits Proliferation and Induces Differentiation of Squamous Cell Carcinoma Cells. PMID:34072393
Deep Learning Improves Pancreatic Cancer Diagnosis Using RNA-Based Variants. PMID:34071263
Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in Saccharomyces cerevisiae. PMID:34071169
Proteomic Analyses of Vitreous in Proliferative Diabetic Retinopathy: Prior Studies and Future Outlook. PMID:34070658
Weighted Gene Co-Expression Network Analysis Reveals Key Genes and Potential Drugs in Abdominal Aortic Aneurysm. PMID:34068179
Cascading from SARS-CoV-2 to Parkinson's Disease through Protein-Protein Interactions. PMID:34066091
Cancer-Associated circRNA-miRNA-mRNA Regulatory Networks: A Meta-Analysis. PMID:34055888
Bioinformatics identification of hub genes and signaling pathways regulated by intravenous immunoglobulin treatment in acute Kawasaki disease. PMID:34055083
Identification of circRNA-miRNA-mRNA networks contributes to explore underlying pathogenesis and therapy strategy of gastric cancer. PMID:34049561
Nuclear Phosphatidylinositol 3,4,5-Trisphosphate Interactome Uncovers an Enrichment in Nucleolar Proteins. PMID:34048982
In Silico Structural, Functional, and Phylogenetic Analysis of Cytochrome (CYPD) Protein Family. PMID:34046497
Computational Biology and Machine Learning Approaches to Understand Mechanistic Microbiome-Host Interactions. PMID:34046017
Identification of diagnostic genes and vital microRNAs involved in rheumatoid arthritis: based on data mining and experimental verification. PMID:34040897
Aviator: a web service for monitoring the availability of web services. PMID:34038559
NetGO 2.0: improving large-scale protein function prediction with massive sequence, text, domain, family and network information. PMID:34038555
3-Nitrobenzanthrone promotes malignant transformation in human lung epithelial cells through the epiregulin-signaling pathway. PMID:34036453
KIF4A as a novel prognostic biomarker in cholangiocarcinoma. PMID:34032761
High expression of guanine nucleotide-binding protein-like-3-like is associated with poor prognosis in esophageal cancer. PMID:34032716
The Cardenolide Glycoside Acovenoside A Interferes with Epidermal Growth Factor Receptor Trafficking in Non-Small Cell Lung Cancer Cells. PMID:34025398
Valproic Acid Protects Against Acute Kidney Injury in Hemorrhage and Trauma. PMID:34023578
RAGE-mediated functional DNA methylated modification contributes to cigarette smoke-induced airway inflammation in mice. PMID:34017996
Prognostic and clinicopathological insights of phosphodiesterase 9A gene as novel biomarker in human colorectal cancer. PMID:34016083
Comparative Analysis on Single- and Multiherb Strategies in Coronary Artery Atherosclerosis Therapy. PMID:34012683
Endosperm and Seed Transcriptomes Reveal Possible Roles for Small RNA Pathways in Wild Tomato Hybrid Seed Failure. PMID:34009298
An overview of graph databases and their applications in the biomedical domain. PMID:34003247
Imputing single-cell RNA-seq data by combining graph convolution and autoencoder neural networks. PMID:33997678
Diagnostic, Therapeutic, and Prognostic Value of the Thrombospondin Family in Gastric Cancer. PMID:33996903
Bioinformatics Investigation and Contribution of Other Chromosomes Besides Chromosome 21 in the Risk of Down Syndrome Development. PMID:33995930
SOX4 as biomarker in hepatitis B virus-associated hepatocellular carcinoma. PMID:33995626
Network Pharmacology-Based Investigation of the Therapeutic Mechanisms of Action of Danning Tablets in Nonalcoholic Fatty Liver Disease. PMID:33995543
Identification of Hub Genes and Their Correlation With Immune Infiltration Cells in Hepatocellular Carcinoma Based on GEO and TCGA Databases. PMID:33995482
mTOR kinase activity disrupts a phosphorylation signaling network in schizophrenia brain. PMID:33990769
A novel ferroptosis-related gene signature for predicting outcomes in cervical cancer. PMID:33989111
Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection. PMID:33986255
Capturing dynamic relevance in Boolean networks using graph theoretical measures. PMID:33983406
Wedelolactone improves the renal injury induced by lipopolysaccharide in HK-2 cells by upregulation of protein tyrosine phosphatase non-receptor type 2. PMID:33983070
Multi-omics analysis of early leaf development in Arabidopsis thaliana. PMID:33982025
Downregulation of ATP6V1A Involved in Alzheimer's Disease via Synaptic Vesicle Cycle, Phagosome, and Oxidative Phosphorylation. PMID:33981384
A high-throughput genome-wide RNAi screen identifies modifiers of survival motor neuron protein. PMID:33979606
Deciphering Pharmacological Mechanism of Buyang Huanwu Decoction for Spinal Cord Injury by Network Pharmacology Approach. PMID:33976706
Surface Roughness of Titanium Orthopedic Implants Alters the Biological Phenotype of Human Mesenchymal Stromal Cells. PMID:33975459
Rare functional genetic variants in COL7A1, COL6A5, COL1A2 and COL5A2 frequently occur in Chiari Malformation Type 1. PMID:33974636
Seven-gene signature on tumor microenvironment for predicting the prognosis of patients with pancreatic cancer. PMID:33968691
Consolidation of network and experimental pharmacology to divulge the antidiabetic action of Ficus benghalensis L. bark. PMID:33968581
Investigation of circRNA-miRNA-mRNA network in colorectal cancer using an integrative bioinformatics approach. PMID:33968341
Viral-Host Interactome Analysis Reveals Chicken STAU2 Interacts With Non-structural Protein 1 and Promotes the Replication of H5N1 Avian Influenza Virus. PMID:33968009
A five metastasis-related long noncoding RNA risk signature for osteosarcoma survival prediction. PMID:33964903
Ketogenic diet-mediated steroid metabolism reprogramming improves the immune microenvironment and myelin growth in spinal cord injury rats according to gene and co-expression network analyses. PMID:33962394
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. PMID:33961781
Genome-wide DNA methylation and RNA-seq analyses identify genes and pathways associated with doxorubicin resistance in a canine diffuse large B-cell lymphoma cell line. PMID:33961622
Comprehensive Analysis of Common Different Gene Expression Signatures in the Neutrophils of Sepsis. PMID:33959663
CXCL1 Clone Evolution Induced by the HDAC Inhibitor Belinostat Might Be a Favorable Prognostic Indicator in Triple-Negative Breast Cancer. PMID:33959656
Hypoxia Constructing the Prognostic Model of Colorectal Adenocarcinoma and Related to the Immune Microenvironment. PMID:33959617
Integrating Network Pharmacology and Experimental Validation to Decipher the Mechanism of Action of Huanglian Jiedu Decoction in Treating Atherosclerosis. PMID:33958856
Modeling of stringent-response reflects nutrient stress induced growth impairment and essential amino acids in different Staphylococcus aureus mutants. PMID:33958641
Identification of seven tumor-educated platelets RNAs for cancer diagnosis. PMID:33955587
Multi-omic analysis elucidates the genetic basis of hydrocephalus. PMID:33951428
SWATH Based Quantitative Proteomics Reveals Significant Lipid Metabolism in Early Myopic Guinea Pig Retina. PMID:33946922
Proteomic Studies of Primary Acute Myeloid Leukemia Cells Derived from Patients Before and during Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid and Valproic Acid. PMID:33946813
Identification of CDC20 as an immune infiltration-correlated prognostic biomarker in hepatocellular carcinoma. PMID:33942202
Peptide array-based interactomics. PMID:33942139
Bioinformatic identification of hub genes and related transcription factors in low shear stress treated endothelial cells. PMID:33941187
Strategies for detecting and identifying biological signals amidst the variation commonly found in RNA sequencing data. PMID:33941086
Comprehensive RNA-Seq Analysis of Potential Therapeutic Targets of Gan-Dou-Fu-Mu Decoction for Treatment of Wilson Disease Using a Toxic Milk Mouse Model. PMID:33935715
MRPL15 is a novel prognostic biomarker and therapeutic target for epithelial ovarian cancer. PMID:33934540
HIF1α-dependent induction of the mitochondrial chaperone TRAP1 regulates bioenergetic adaptations to hypoxia. PMID:33934112
Deep learning integration of molecular and interactome data for protein-compound interaction prediction. PMID:33933121
Identification of PTP1B regulators from Cymbopogon citratus and its enrichment analysis for diabetes mellitus. PMID:33928007
KLK3 SNP-SNP interactions for prediction of prostate cancer aggressiveness. PMID:33927218
Stepwise pathogenic evolution of Mycobacterium abscessus. PMID:33926925
Best practices on the differential expression analysis of multi-species RNA-seq. PMID:33926528
A Novel Method to Predict Drug-Target Interactions Based on Large-Scale Graph Representation Learning. PMID:33925568
Bone Marrow-Derived IL-1Ra Increases TNF Levels Poststroke. PMID:33924148
Blood Pressure Regulation Evolved from Basic Homeostatic Components. PMID:33923023
mRNA Expressions of Candidate Genes in Gestational Day 16 Conceptus and Corresponding Endometrium in Repeat Breeder Dairy Cows with Suboptimal Uterine Environment Following Transfer of Different Quality Day 7 Embryos. PMID:33920430
A Network Medicine Approach for Drug Repurposing in Duchenne Muscular Dystrophy. PMID:33918694
Identification of Hub Genes Associated With Melanoma Development by Comprehensive Bioinformatics Analysis. PMID:33912448
Computational and In Vitro Analysis of Plumbagin's Molecular Mechanism for the Treatment of Hepatocellular Carcinoma. PMID:33912033
Transcriptome Sequencing Reveals the Potential Mechanisms of Modified Electroconvulsive Therapy in Schizophrenia. PMID:33910328
Investigation and verification of the clinical significance and perspective of natural killer group 2 member D ligands in colon adenocarcinoma. PMID:33909599
Gene expression analysis of MCF7 cell lines of breast cancer treated with herbal extract of Cissampelos pareira revealed association with viral diseases. PMID:33907720
Prediction of host-pathogen protein interactions by extended network model. PMID:33907496
Comprehensive Identification of Bridge Genes to Explain the Progression from Chronic Hepatitis B Virus Infection to Hepatocellular Carcinoma. PMID:33907440
Potential mechanisms of Guizhi decoction against hypertension based on network pharmacology and Dahl salt-sensitive rat model. PMID:33906674
Identification of key biomarkers for thyroid cancer by integrative gene expression profiles. PMID:33899546
Expression analysis of progesterone‑regulated miRNAs in cells derived from human glioblastoma. PMID:33899118
The First Contact of Human Dendritic Cells With Trypanosoma cruzi Reveals Response to Virus as an Unexplored Central Pathway. PMID:33897690
Proteomic profiling of soft tissue sarcomas with SWATH mass spectrometry. PMID:33895336
Integrated bioinformatics analysis reveals novel key biomarkers and potential candidate small molecule drugs in gestational diabetes mellitus. PMID:33890634
Identification of the Key Regulators of Spina Bifida Through Graph-Theoretical Approach. PMID:33889172
Arena3Dweb: interactive 3D visualization of multilayered networks. PMID:33885790
A Combination of RNA-Seq Analysis and Use of TCGA Database for Determining the Molecular Mechanism and Identifying Potential Drugs for GJB1 in Ovarian Cancer. PMID:33883906
Weighted gene co expression network analysis (WGCNA) with key pathways and hub-genes related to micro RNAs in ischemic stroke. PMID:33880887
Exploring the Pharmacological Mechanism of Duhuo Jisheng Decoction in Treating Osteoporosis Based on Network Pharmacology. PMID:33880122
Identification of TNIK as a novel potential drug target in thyroid cancer based on protein druggability prediction. PMID:33879700
Comprehensive analyses of competing endogenous RNA networks reveal potential biomarkers for predicting hepatocellular carcinoma recurrence. PMID:33879119
Genome-wide analysis of SET-domain group histone methyltransferases in apple reveals their role in development and stress responses. PMID:33874904
Quantitative proteome comparison of human hearts with those of model organisms. PMID:33872299
Three Immune-Related Prognostic mRNAs as Therapeutic Targets for Pancreatic Cancer. PMID:33869254
New Perspectives in Different Gene Expression Profiles for Early and Locally Advanced Non-Small Cell Lung Cancer Stem Cells. PMID:33868998
An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression. PMID:33867976
Utilizing network pharmacology and molecular docking to explore the underlying mechanism of Guizhi Fuling Wan in treating endometriosis. PMID:33859874
Role of Cigarette Smoke on Angiotensin-Converting Enzyme-2 Protein Membrane Expression in Bronchial Epithelial Cells Using an Air-Liquid Interface Model. PMID:33859566
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes. PMID:33859415
Potential Genes and Mechanisms Linking Intracerebral Hemorrhage and Depression: A Bioinformatics-Based Study. PMID:33854363
Methamphetamine-induced changes in myocardial gene transcription are sex-dependent. PMID:33845768
Nephron-deficient HSRA rats exhibit renal injury with age but have limited renal damage from streptozotocin-induced hyperglycemia. PMID:33843272
Integrated Multi-Omic Analyses of the Genomic Modifications by Gut Microbiome-Derived Metabolites of Epicatechin, 5-(4'-Hydroxyphenyl)-γ-Valerolactone, in TNFalpha-Stimulated Primary Human Brain Microvascular Endothelial Cells. PMID:33841078
Bioinformatics and machine learning approach identifies potential drug targets and pathways in COVID-19. PMID:33839760
Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway. PMID:33838689
Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families. PMID:33837273
Whole-Transcriptome RNA Sequencing Reveals Significant Differentially Expressed mRNAs, miRNAs, and lncRNAs and Related Regulating Biological Pathways in the Peripheral Blood of COVID-19 Patients. PMID:33833618
A data-driven approach for the discovery of biomarkers associated with thyroid eye disease. PMID:33832456
Identification of key genes associated with secondary metabolites biosynthesis by system network analysis in Valeriana officinalis. PMID:33829347
High BLM Expression Predicts Poor Clinical Outcome and Contributes to Malignant Progression in Human Cholangiocarcinoma. PMID:33828983
Identification of MiR-93-5p Targeted Pathogenic Markers in Acute Myeloid Leukemia through Integrative Bioinformatics Analysis and Clinical Validation. PMID:33828590
Polycystic Ovary Syndrome: the Epigenetics Behind the Disease. PMID:33826098
Maternal-Fetal Immune Responses in Pregnant Women Infected with SARS-CoV-2. PMID:33821263
Protein interactome of the Cancerous Inhibitor of protein phosphatase 2A (CIP2A) in Th17 cells. PMID:33817627
Network bioinformatics analysis provides insight into drug repurposing for COVID-19. PMID:33817623
Reducing neutrophil exposure to oxygen allows their basal state maintenance. PMID:33811670
The Constitutive Extracellular Protein Release by Acute Myeloid Leukemia Cells-A Proteomic Study of Patient Heterogeneity and Its Modulation by Mesenchymal Stromal Cells. PMID:33806032
Overexpression of Human Syndecan-1 Protects against the Diethylnitrosamine-Induced Hepatocarcinogenesis in Mice. PMID:33801718
Retinal Genomic Fabric Remodeling after Optic Nerve Injury. PMID:33799827
In Silico Network Analysis of Ingredients of Cornus officinalis in Osteoporosis. PMID:33795629
LAMB1 Is Related to the T Stage and Indicates Poor Prognosis in Gastric Cancer. PMID:33784890
Study on the Mechanism of Jiawei Shengjiang Powder in Improving Male Asthma-Induced Asthenospermia Based on Network Pharmacology and Bioinformatics. PMID:33776422
MED15 prion-like domain forms a coiled-coil responsible for its amyloid conversion and propagation. PMID:33772081
Identification and Analysis of Potential Key Genes Associated With Hepatocellular Carcinoma Based on Integrated Bioinformatics Methods. PMID:33767726
Comprehensive analysis of molecular pathways and key genes involved in lumbar disc herniation. PMID:33761671
CorGO: An Integrated Method for Clustering Functionally Similar Genes. PMID:33761117
Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen. PMID:33759347
Anti-Lung Cancer Targets of Radix Paeoniae Rubra and Biological Molecular Mechanism: Network Pharmacological Analyses and Experimental Validation. PMID:33758512
TALE: Transformer-based protein function Annotation with joint sequence-Label Embedding. PMID:33755048
Comprehensive investigation of the clinical significance of long non-coding RNA HOXA-AS2 in acute myeloid leukemia using genome-wide RNA sequencing dataset. PMID:33754013
Identification of differential DNA methylation alterations of ovarian cancer in peripheral whole blood based on within-sample relative methylation orderings. PMID:33749504
Mapping Novel Biomarkers of Liver Injury by Tissue Proteomic Analysis. PMID:33748626
C3AR1 mRNA as a Potential Therapeutic Target Associates With Clinical Outcomes and Tumor Microenvironment in Osteosarcoma. PMID:33748161
A network pharmacology-based investigation on the bioactive ingredients and molecular mechanisms of Gelsemium elegans Benth against colorectal cancer. PMID:33743701
Gene Set Index Based on Different Modules May Help Differentiate the Mechanisms of Alzheimer's Disease and Vascular Dementia. PMID:33737807
Adipose most abundant 2 protein is a predictive marker for cisplatin sensitivity in cancers. PMID:33737617
Nidogen-1 expression is associated with overall survival and temozolomide sensitivity in low-grade glioma patients. PMID:33735110
The genetic architecture of structural left-right asymmetry of the human brain. PMID:33723403
Single-Cell RNA Sequencing and Quantitative Proteomics Analysis Elucidate Marker Genes and Molecular Mechanisms in Hypoplastic Left Heart Patients With Heart Failure. PMID:33718359
Quantitative Proteomics Reveals that the OGT Interactome Is Remodeled in Response to Oxidative Stress. PMID:33716169
Integrated analysis of RNA-binding proteins in thyroid cancer. PMID:33711033
Identification of TRIM56 as a Potential Biomarker for Lung Adenocarcinoma. PMID:33707970
A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models. PMID:33705438
Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models. PMID:33693642
Aberrant cytoplasmic intron retention is a blueprint for RNA binding protein mislocalization in VCP-related amyotrophic lateral sclerosis. PMID:33693641
Identification and Validation of Key Genes in Hepatocellular Carcinoma by Bioinformatics Analysis. PMID:33688500
An Apoptotic Gene Signature for the Prognosis of Hepatocellular Carcinoma. PMID:33688206
Computational Analysis Indicates That PARP1 Acts as a Histone Deacetylases Interactor Sharing Common Lysine Residues for Acetylation, Ubiquitination, and SUMOylation in Alzheimer's and Parkinson's Disease. PMID:33681613
Integrated Bioinformatics Analysis Exhibits Pivotal Exercise-Induced Genes and Corresponding Pathways in Malignant Melanoma. PMID:33679872
Luteolin Alleviates Methamphetamine-Induced Hepatotoxicity by Suppressing the p53 Pathway-Mediated Apoptosis, Autophagy, and Inflammation in Rats. PMID:33679421
M2 macrophage-derived exosomal microRNAs inhibit cell migration and invasion in gliomas through PI3K/AKT/mTOR signaling pathway. PMID:33676540
Eosinophil Responses at the Airway Epithelial Barrier during the Early Phase of Influenza A Virus Infection in C57BL/6 Mice. PMID:33673645
The Alphaviral Capsid Protein Inhibits IRAK1-Dependent TLR Signaling. PMID:33673546
Transcriptome Analysis Reveals the Genes Involved in Bifidobacterium Longum FGSZY16M3 Biofilm Formation. PMID:33672820
Defective Mitochondrial Dynamics Underlie Manganese-Induced Neurotoxicity. PMID:33666854
The long non-coding RNA MEG3 plays critical roles in the pathogenesis of cholesterol gallstone. PMID:33665015
Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL). PMID:33664368
Akt Is S-Palmitoylated: A New Layer of Regulation for Akt. PMID:33659252
An Integrative Pharmacology-Based Pattern to Uncover the Pharmacological Mechanism of Ginsenoside H Dripping Pills in the Treatment of Depression. PMID:33658934
Transcriptome-Wide High-Throughput m6A Sequencing of Differential m6A Methylation Patterns in the Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes Cell Line MH7A. PMID:33658830
Expression and Functional Relevance of ANXA1 in Hypopharyngeal Carcinoma with Lymph Node Metastasis. PMID:33658802
Protein Interactomes of Streptococcus mutans YidC1 and YidC2 Membrane Protein Insertases Suggest SRP Pathway-Independent- and -Dependent Functions, Respectively. PMID:33658280
The important herbal pair for the treatment of COVID-19 and its possible mechanisms. PMID:33658066
Integrated analysis of label-free quantitative proteomics and bioinformatics reveal insights into signaling pathways in male breast cancer. PMID:33656060
Diabetes induces dysregulation of microRNAs associated with survival, proliferation and self-renewal in cardiac progenitor cells. PMID:33655378
The genome sequence of Aloe vera reveals adaptive evolution of drought tolerance mechanisms. PMID:33644713
Coupling of Co-expression Network Analysis and Machine Learning Validation Unearthed Potential Key Genes Involved in Rheumatoid Arthritis. PMID:33643380
Transcriptional Biomarkers in Oral Cancer: An Integrative Analysis and the Cancer Genome Atlas Validation. PMID:33639650
System-wide identification and prioritization of enzyme substrates by thermal analysis. PMID:33637753
Computational screening of potential glioma-related genes and drugs based on analysis of GEO dataset and text mining. PMID:33635875
Forty-three key gene expressions involved in the effect of indoleamine 2,3-dioxygenase 1 expression on cancer prognosis may be a potential indoleamine 2,3-dioxygenase 1 inhibitor biomarker. PMID:33634987
Exploring the conservation of Alzheimer-related pathways between H. sapiens and C. elegans: a network alignment approach. PMID:33633188
Comprehensive analysis of tumour mutational burden and its clinical significance in prostate cancer. PMID:33632199
Functional analysis of brain derived neurotrophic factor (BDNF) in Huntington's disease. PMID:33631722
Identification of UBE2C as hub gene in driving prostate cancer by integrated bioinformatics analysis. PMID:33630978
Five key aspects of metaproteomics as a tool to understand functional interactions in host-associated microbiomes. PMID:33630960
Evolution, structure and emerging roles of C1ORF112 in DNA replication, DNA damage responses, and cancer. PMID:33625522
The novel roles of virus infection-associated gene CDKN1A in chemoresistance and immune infiltration of glioblastoma. PMID:33621203
Parallel Genomic Changes Drive Repeated Evolution of Placentas in Live-Bearing Fish. PMID:33620468
Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin. PMID:33618800
A Multi-OMICs Approach Sheds Light on the Higher Yield Phenotype and Enhanced Abiotic Stress Tolerance in Tobacco Lines Expressing the Carrot lycopene β-cyclase1 Gene. PMID:33613605
Blood Coagulation Factor Fibrinogen in Tumor Pathogenesis of Central Nervous System B-Cell Lymphoma. PMID:33608067
Detecting Causal Variants in Mendelian Disorders Using Whole-Genome Sequencing. PMID:33606250
RNAi activation with homologous and heterologous sequences that induce resistance against the begomovirus Pepper golden mosaic virus (PepGMV). PMID:33604230
Integrated Analysis of Key Genes and Pathways Involved in Nonalcoholic Steatohepatitis Improvement After Roux-en-Y Gastric Bypass Surgery. PMID:33603714
Optimized expression of Hfq protein increases Escherichia coli growth. PMID:33602295
Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes. PMID:33589840
Mapping drug-target interactions and synergy in multi-molecular therapeutics for pressure-overload cardiac hypertrophy. PMID:33589646
Evaluation of the susceptibility and fatality of lung cancer patients towards the COVID-19 infection: A systemic approach through analyzing the ACE2, CXCL10 and their co-expressed genes. PMID:33585826
Construction of Bone Metastasis-Specific Regulation Network Based on Prognostic Stemness-Related Signatures in Breast Invasive Carcinoma. PMID:33585235
The long non-coding RNA GHSROS reprograms prostate cancer cell lines toward a more aggressive phenotype. PMID:33585078
Evaluation of long-term consumption of omeprazole disadvantages: a network analysis. PMID:33585010
Showing NAFLD, as a key connector disease between Alzheimer's disease and diabetes via analysis of systems biology. PMID:33585009
Identification of Protein Subcellular Localization With Network and Functional Embeddings. PMID:33584818
Cold Adaptation Mechanisms of a Snow Alga Chlamydomonas nivalis During Temperature Fluctuations. PMID:33584575
PRMT5 inhibition disrupts splicing and stemness in glioblastoma. PMID:33579912
Identification of new proteins related with cisplatin resistance in Saccharomyces cerevisiae. PMID:33576883
NetQuilt: Deep Multispecies Network-based Protein Function Prediction using Homology-informed Network Similarity. PMID:33576802
UniProt-Related Documents (UniReD): assisting wet lab biologists in their quest on finding novel counterparts in a protein network. PMID:33575553
A Network Pharmacology Approach to Estimate Potential Targets of the Active Ingredients of Epimedium for Alleviating Mild Cognitive Impairment and Treating Alzheimer's Disease. PMID:33574879
CC Chemokine Receptors in Lung Adenocarcinoma: The Inflammation-Related Prognostic Biomarkers and Immunotherapeutic Targets. PMID:33574689
Sinomenine Inhibits the Growth of Ovarian Cancer Cells Through the Suppression of Mitosis by Down-Regulating the Expression and the Activity of CDK1. PMID:33574676
Role of JAK-STAT Pathway in Broiler Chicks Fed with Chestnut Tannins. PMID:33572892
Mucociliary Respiratory Epithelium Integrity in Molecular Defense and Susceptibility to Pulmonary Viral Infections. PMID:33572760
miR-16-5p Promotes Erythroid Maturation of Erythroleukemia Cells by Regulating Ribosome Biogenesis. PMID:33572085
Identification of Functional Interactome of Colistin Resistance Protein MCR-1 in Escherichia coli. PMID:33569043
Integrated bioinformatic analysis identifies COL4A3, COL4A4, and KCNJ1 as key biomarkers in Wilms tumor. PMID:33564352
System Pharmacology-Based Strategy to Decode the Synergistic Mechanism of GanDouLing for Wilson's Disease. PMID:33564316
miR-142-3p regulates cortical oligodendrocyte gene co-expression networks associated with tauopathy. PMID:33555315
Gene Expression Changes and Associated Pathways Involved in the Progression of Prostate Cancer Advanced Stages. PMID:33552133
BioMaster: An Integrated Database and Analytic Platform to Provide Comprehensive Information About BioBrick Parts. PMID:33552037
OsTPR boosts the superior grains through increase in upper secondary rachis branches without incurring a grain quality penalty. PMID:33544455
Pan-Cancer analysis of the expression and regulation of matrisome genes across 32 tumor types. PMID:33543003
A Novel mRNA-miRNA Regulatory Sub-Network Associated With Prognosis of Metastatic Clear Cell Renal Cell Carcinoma. PMID:33542901
Emodin Inhibits the Proliferation of MCF-7 Human Breast Cancer Cells Through Activation of Aryl Hydrocarbon Receptor (AhR). PMID:33542691
The canine activated platelet secretome (CAPS): A translational model of thrombin-evoked platelet activation response. PMID:33537530
Identification of a Five-Gene Prognostic Model and Its Potential Drug Repurposing in Colorectal Cancer Based on TCGA, GTEx and GEO Databases. PMID:33537062
Identification of Genes with Altered Methylation and Its Role in Early Diagnosis of Sepsis-Induced Acute Respiratory Distress Syndrome. PMID:33536775
Neutrophil degranulation interconnects over-represented biological processes in atrial fibrillation. PMID:33536523
Novel prognostic genes and subclasses of acute myeloid leukemia revealed by survival analysis of gene expression data. PMID:33536020
Carbon ion triggered immunogenic necroptosis of nasopharyngeal carcinoma cells involving necroptotic inhibitor BCL-x. PMID:33531997
Role of Antizyme Inhibitor Proteins in Cancers and Beyond. PMID:33531815
CCT6A, a novel prognostic biomarker for Ewing sarcoma. PMID:33530265
Association of regular aerobic exercises and neuromuscular junction variants with incidence of frailty: an analysis of the Chinese Longitudinal Health and Longevity Survey. PMID:33527771
The Role of Non-Canonical Hsp70s (Hsp110/Grp170) in Cancer. PMID:33525518
Human pathways in animal models: possibilities and limitations. PMID:33524155
LAPTM5 Plays a Key Role in the Diagnosis and Prognosis of Testicular Germ Cell Tumors. PMID:33521125
Evolutionarily Conserved Long Non-coding RNA Regulates Gene Expression in Cytokine Storm During COVID-19. PMID:33520952
Gene ontology enrichment analysis of α-amylase inhibitors from Duranta repens in diabetes mellitus. PMID:33520800
Contributions and Prognostic Values of N6-Methyladenosine RNA Methylation Regulators in Hepatocellular Carcinoma. PMID:33519919
Study on mechanism of matrine in treatment of COVID-19 combined with liver injury by network pharmacology and molecular docking technology. PMID:33517789
Potential effect of Maxing Shigan decoction against coronavirus disease 2019 (COVID-19) revealed by network pharmacology and experimental verification. PMID:33513419
Network Pharmacology-Based Analysis on the Mechanism of Action of Ephedrae Herba-Cinnamomi Ramulus Couplet Medicines in the Treatment for Psoriasis. PMID:33513128
Functional lncRNA-miRNA-mRNA Networks in Response to Baicalein Treatment in Hepatocellular Carcinoma. PMID:33511213
Comprehensive Analysis of ceRNA Regulation Network Involved in the Development of Coronary Artery Disease. PMID:33511207
Effect of Gegenqinlian decoction on intestinal mucosal flora in mice with diarrhea induced by high temperature and humidity treatment. PMID:33505838
Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. PMID:33503434
In silico characterization of bacterial chitinase: illuminating its relationship with archaeal and eukaryotic cousins. PMID:33495874
Bioinformatics analysis identifies biomarkers associated with poor prognosis in diffuse‑type gastric cancer. PMID:33495829
The roles of PARP-1 and XPD and their potential interplay in repairing bupivacaine-induced neuron oxidative DNA damage. PMID:33495403
Manganese exposure in juvenile C57BL/6 mice increases glial inflammatory responses in the substantia nigra following infection with H1N1 influenza virus. PMID:33493177
High expression of collagen 1A2 promotes the proliferation and metastasis of esophageal cancer cells. PMID:33490184
Identification of IL10RA by Weighted Correlation Network Analysis and in vitro Validation of Its Association With Prognosis of Metastatic Melanoma. PMID:33490091
Detecting operons in bacterial genomes via visual representation learning. PMID:33483546
Integrative computational approach identifies drug targets in CD4+ T-cell-mediated immune disorders. PMID:33483502
MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development. PMID:33482885
A disorder-related variant (E420K) of a PP2A-regulatory subunit (PPP2R5D) causes constitutively active AKT-mTOR signaling and uncoordinated cell growth. PMID:33482199
HEDGEHOG/GLI Modulates the PRR11-SKA2 Bidirectional Transcription Unit in Lung Squamous Cell Carcinomas. PMID:33477943
System-Wide Pollution of Biomedical Data: Consequence of the Search for Hub Genes of Hepatocellular Carcinoma Without Spatiotemporal Consideration. PMID:33475988
DOMINO: a network-based active module identification algorithm with reduced rate of false calls. PMID:33471440
GSK-3β Regulates the Expression of P21 to Promote the Progression of Chordoma. PMID:33469364
Bioinformatics analysis of miRNA and mRNA expression profiles to reveal the key miRNAs and genes in osteoarthritis. PMID:33468167
Melanoma Cell Resistance to Vemurafenib Modifies Inter-Cellular Communication Signals. PMID:33467521
Does KRAS Play a Role in the Regulation of Colon Cancer Cells-Derived Exosomes? PMID:33466836
Identification of potential biomarkers of peripheral blood mononuclear cell in hepatocellular carcinoma using bioinformatic analysis: A protocol for systematic review and meta-analysis. PMID:33466191
Identification of RNA-binding protein SNRPA1 for prognosis in prostate cancer. PMID:33460399
Constructing a ceRNA-immunoregulatory network associated with the development and prognosis of human atherosclerosis through weighted gene co-expression network analysis. PMID:33460396
Exploring the treatment of COVID-19 with Yinqiao powder based on network pharmacology. PMID:33452734
Bioinformatics analysis of differentially expressed genes in tumor and paracancerous tissues of patients with lung adenocarcinoma. PMID:33447425
Identification of Four Genes as Prognosis Signatures in Lung Adenocarcinoma Microenvironment. PMID:33447073
Bone Marrow Failure Syndromes, Overlapping Diseases with a Common Cytokine Signature. PMID:33445786
Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington's disease mice. PMID:33441541
Classification of Cancer Types Using Graph Convolutional Neural Networks. PMID:33437754
A systems pharmacology approach to identify the autophagy-inducing effects of Traditional Persian medicinal plants. PMID:33431946
DF-MDA: An effective diffusion-based computational model for predicting miRNA-disease association. PMID:33429082
TMEM158 May Serve as a Diagnostic Biomarker for Anaplastic Thyroid Carcinoma: An Integrated Bioinformatic Analysis. PMID:33428142
RNA-Seq Whole Transcriptome Analysis of Bovine Mammary Epithelial Cells in Response to Intracellular Staphylococcus aureus. PMID:33426011
Prediction of lncRNA-disease associations via an embedding learning HOPE in heterogeneous information networks. PMID:33425486
Analysis of Hub Genes Involved in Distinction Between Aged and Fetal Bone Marrow Mesenchymal Stem Cells by Robust Rank Aggregation and Multiple Functional Annotation Methods. PMID:33424919
Elucidating the network features and evolutionary attributes of intra- and interspecific protein-protein interactions between human and pathogenic bacteria. PMID:33420198
Uncovering the secretome of mesenchymal stromal cells exposed to healthy, traumatic, and degenerative intervertebral discs: a proteomic analysis. PMID:33413584
METTL3/YTHDF2 m6A axis accelerates colorectal carcinogenesis through epigenetically suppressing YPEL5. PMID:33411363
The histone methyltransferase inhibitor A-366 enhances hemoglobin expression in erythroleukemia cells upon co-exposure with chemical inducers in culture. PMID:33407944
Six Novel Biomarkers for Diagnosis and Prognosis of Esophageal squamous cell carcinoma: validated by scRNA-seq and qPCR. PMID:33403046
Localization and Dynamics of the Methionine Sulfoxide Reductases MsrB1 and MsrB2 in Beech Seeds. PMID:33401671
Identification of lncRNA-mRNA Regulatory Module to Explore the Pathogenesis and Prognosis of Melanoma. PMID:33392203
MYC dysfunction modulates stemness and tumorigenesis in breast cancer. PMID:33390842
Bioinformatics Analyses of Potential miRNA-mRNA Regulatory Axis in HBV-related Hepatocellular Carcinoma. PMID:33390802
Immunological analysis and differential genes screening of venous thromboembolism. PMID:33388092
Integrated Analysis of Key Pathways and Drug Targets Associated With Vogt-Koyanagi-Harada Disease. PMID:33384687
Identification of Core Prognosis-Related Candidate Genes in Chinese Gastric Cancer Population Based on Integrated Bioinformatics. PMID:33381592
The Underlying Mechanism of Paeonia lactiflora Pall. in Parkinson's Disease Based on a Network Pharmacology Approach. PMID:33381034
KIF14 and KIF23 Promote Cell Proliferation and Chemoresistance in HCC Cells, and Predict Worse Prognosis of Patients with HCC. PMID:33380832
Alcoholic and Non-Alcoholic Beer Modulate Plasma and Macrophage microRNAs Differently in a Pilot Intervention in Humans with Cardiovascular Risk. PMID:33379359
The Extracellular Bone Marrow Microenvironment-A Proteomic Comparison of Constitutive Protein Release by In Vitro Cultured Osteoblasts and Mesenchymal Stem Cells. PMID:33379263
Cell type-specific transcriptomics identifies neddylation as a novel therapeutic target in multiple sclerosis. PMID:33374005
Differential alternative splicing between hepatocellular carcinoma with normal and elevated serum alpha-fetoprotein. PMID:33371894
Novel therapeutic compounds for prostate adenocarcinoma treatment: An analysis using bioinformatic approaches and the CMap database. PMID:33371142
Comprehensive Integration of Single-Cell Transcriptional Profiling Reveals the Heterogeneities of Non-cardiomyocytes in Healthy and Ischemic Hearts. PMID:33365332
An Iron Metabolism-Related SLC22A17 for the Prognostic Value of Gastric Cancer. PMID:33363382
Computational and network pharmacology analysis of bioflavonoids as possible natural antiviral compounds in COVID-19. PMID:33363251
Acyl-CoA Thioesterase 8 and 11 as Novel Biomarkers for Clear Cell Renal Cell Carcinoma. PMID:33362855
Supplementing chestnut tannins in the broiler diet mediates a metabolic phenotype of the ceca. PMID:33357706
From miRNA Target Gene Network to miRNA Function: miR-375 Might Regulate Apoptosis and Actin Dynamics in the Heart Muscle via Rho-GTPases-Dependent Pathways. PMID:33352947
Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation. PMID:33349623
Topological network measures for drug repositioning. PMID:33348366
Elevated CDK5R1 predicts worse prognosis in hepatocellular carcinoma based on TCGA data. PMID:33346796
Development and Validation of a Five-Gene Signature to Predict Relapse-Free Survival in Multiple Sclerosis. PMID:33343487
Expression of CAMK1 and its association with clinicopathologic characteristics in pancreatic cancer. PMID:33342045
Renal Carcinoma Is Associated With Increased Risk of Coronavirus Infections. PMID:33330620
Membrane Proteocomplexome of Campylobacter jejuni Using 2-D Blue Native/SDS-PAGE Combined to Bioinformatics Analysis. PMID:33329413
Aortic Gene Expression Profiles Show How ApoA-I Levels Modulate Inflammation, Lysosomal Activity, and Sphingolipid Metabolism in Murine Atherosclerosis. PMID:33327742
Gene Co-expression Networks Identifies Common Hub Genes Between Cutaneous Sarcoidosis and Discoid Lupus Erythematosus. PMID:33324666
Classifying Breast Cancer Molecular Subtypes by Using Deep Clustering Approach. PMID:33324444
Postnatal Growth Restriction in Mice Alters Cardiac Protein Composition and Leads to Functional Impairment in Adulthood. PMID:33322681
Correlation of carbonic anhydrase 9 (CA9) with pathological T-stage and prognosis in patients with oral tongue squamous cell carcinoma. PMID:33313266
The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1. PMID:33301474
Overexpression of P4HA1 Is Correlated with Poor Survival and Immune Infiltrates in Lung Adenocarcinoma. PMID:33299876
Radiosensitivity-Related Genes and Clinical Characteristics of Nasopharyngeal Carcinoma. PMID:33299859
Differently expressed microRNA in response to the first Ig replacement therapy in common variable immunodeficiency patients. PMID:33293557
Identification of metabolism-associated genes and construction of a prognostic signature in bladder cancer. PMID:33292266
ZBTB7A, a potential biomarker for prognosis and immune infiltrates, inhibits progression of endometrial cancer based on bioinformatics analysis and experiments. PMID:33292231
Differential expression and bioinformatic analysis of circRNA in nonalcoholic steatohepatitis cirrhosis. PMID:33284878
Identification of key genes in lung adenocarcinoma based on a competing endogenous RNA network. PMID:33281971
Identification and Expression Analysis of Long Non-coding RNA in Large Yellow Croaker (Larimichthys crocea) in Response to Cryptocaryon irritans Infection. PMID:33281881
Replaying the evolutionary tape to investigate subgenome dominance in allopolyploid Brassica napus. PMID:33280122
Diurnal dynamics of the Arabidopsis rosette proteome and phosphoproteome. PMID:33278033
Screening of T Cell-Related Long Noncoding RNA-MicroRNA-mRNA Regulatory Networks in Non-Small-Cell Lung Cancer. PMID:33274216
On the lifetime of bioinformatics web services. PMID:33270886
Aqueous Fibronectin Correlates With Severity of Macular Edema and Visual Acuity in Patients With Branch Retinal Vein Occlusion: A Proteome Study. PMID:33270842
N6-methyladenine-related genes affect biological behavior and the prognosis of glioma. PMID:33264518
Programmed death 1, ligand 1 and 2 correlated genes and their association with mutation, immune infiltration and clinical outcomes of hepatocellular carcinoma. PMID:33250959
Network pharmacology of AYUSH recommended immune-boosting medicinal plants against COVID-19. PMID:33250601
Overexpression of BASP1 Indicates a Poor Prognosis in Head and Neck Squamous Cell Carcinoma. PMID:33247706
Identification of the anti-breast cancer targets of triterpenoids in Liquidambaris Fructus and the hints for its traditional applications. PMID:33246450
Identification of hub genes associated with the pathogenesis of diffuse large B-cell lymphoma subtype one characterized by host response via integrated bioinformatic analyses. PMID:33240622
Comprehensive analysis and identification of key genes and signaling pathways in the occurrence and metastasis of cutaneous melanoma. PMID:33240619
Multiple functions of TBCK protein in neurodevelopment disorders and tumors. PMID:33240423
Improving existing analysis pipeline to identify and analyze cancer driver genes using multi-omics data. PMID:33239644
Initial response of ovarian tissue transcriptome to vitrification or microwave-assisted dehydration in the domestic cat model. PMID:33238878
Improving biomedical named entity recognition with syntactic information. PMID:33238875
Noise Exposures Causing Hearing Loss Generate Proteotoxic Stress and Activate the Proteostasis Network. PMID:33238128
Bioinformatics Analysis Identifies a Novel Role of GINS1 Gene in Colorectal Cancer. PMID:33235499
Reduced lipolysis in lipoma phenocopies lipid accumulation in obesity. PMID:33235355
Exploring the mechanism of resistance to sorafenib in two hepatocellular carcinoma cell lines. PMID:33234725
Differential Gene Expression in Longissimus Dorsi Muscle of Hanwoo Steers-New Insight in Genes Involved in Marbling Development at Younger Ages. PMID:33233382
The Potential Effects of Curcumin on Pulmonary Fibroblasts of Idiopathic Pulmonary Fibrosis (IPF)-Approaching with Next-Generation Sequencing and Bioinformatics. PMID:33233354
Inhibition of 3-phosphoinositide-dependent protein kinase 1 (PDK1) can revert cellular senescence in human dermal fibroblasts. PMID:33229519
Development and validation of an RNA binding protein-associated prognostic model for hepatocellular carcinoma. PMID:33228611
Genomics and prognosis analysis of epithelial-mesenchymal transition in colorectal cancer patients. PMID:33228590
Computational gene expression profiling in the exploration of biomarkers, non-coding functional RNAs and drug perturbagens for COVID-19. PMID:33228475
Identification of Spindle and Kinetochore-Associated Family Genes as Therapeutic Targets and Prognostic Biomarkers in Pancreas Ductal Adenocarcinoma Microenvironment. PMID:33224872
Comprehensive proteomic atlas of skin biomatrix scaffolds reveals a supportive microenvironment for epidermal development. PMID:33224464
Investigating the Effects of Ibuprofen on the Gene Expression Profile in Hippocampus of Mice Model of Alzheimer's Disease through Bioinformatics Analysis. PMID:33224242
Prognostic Significance of Prostaglandin-Endoperoxide Synthase-2 Expressions in Human Breast Carcinoma: A Multiomic Approach. PMID:33223820
Vascular endothelial growth factor receptor-2 and its association with tumor immune regulatory gene expression in hepatocellular carcinoma. PMID:33223512
Chronic exposure to TNF reprograms cell signaling pathways in fibroblast-like synoviocytes by establishing long-term inflammatory memory. PMID:33219307
Comprehensive analysis of partial epithelial mesenchymal transition-related genes in hepatocellular carcinoma. PMID:33215860
A Potential Theragnostic Regulatory Axis for Arthrofibrosis Involving Adiponectin (ADIPOQ) Receptor 1 and 2 (ADIPOR1 and ADIPOR2), TGFβ1, and Smooth Muscle α-Actin (ACTA2). PMID:33213041
Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression. PMID:33207193
Construction of a Potential Breast Cancer-Related miRNA-mRNA Regulatory Network. PMID:33204705
Proteomic and Systematic Functional Profiling Unveils Citral Targeting Antibiotic Resistance, Antioxidant Defense, and Biofilm-Associated Two-Component Systems of Acinetobacter baumannii To Encumber Biofilm and Virulence Traits. PMID:33203690
Genome-wide transcriptional changes triggered by water deficit on a drought-tolerant common bean cultivar. PMID:33203368
Potential Diagnostic and Prognostic Utility of miR-141, miR-181b1, and miR-23b in Breast Cancer. PMID:33202602
Bile Ductal Transcriptome Identifies Key Pathways and Hub Genes in Clonorchis sinensis-Infected Sprague-Dawley Rats. PMID:33202503
In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis. PMID:33200027
Comprehensive Identification of Key Genes Involved in Development of Diabetes Mellitus-Related Atherogenesis Using Weighted Gene Correlation Network Analysis. PMID:33195466
In silico Analysis Excavates A Novel Competing Endogenous RNA Subnetwork in Adolescent Idiopathic Scoliosis. PMID:33195333
Transcriptome-wide identification of MAPKKK genes in bermudagrass (Cynodon dactylon L.) and their potential roles in low temperature stress responses. PMID:33194398
Mechanisms of Core Chinese Herbs against Colorectal Cancer: A Study Based on Data Mining and Network Pharmacology. PMID:33193800
Nicotinamide N-Methyltransferase Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Gastric Cancer. PMID:33193702
Underlying Mechanisms and Candidate Drugs for COVID-19 Based on the Connectivity Map Database. PMID:33193639
Identification of Immune Cell Infiltration and Immune-Related Genes in the Tumor Microenvironment of Glioblastomas. PMID:33193404
Expression Profile of GINS Complex Predicts the Prognosis of Pancreatic Cancer Patients. PMID:33192076
Network pharmacology, molecular docking integrated surface plasmon resonance technology reveals the mechanism of Toujie Quwen Granules against coronavirus disease 2019 pneumonia. PMID:33191068
Molecular identification of protein kinase C beta in Alzheimer's disease. PMID:33186918
Identification of potential target genes and crucial pathways in small cell lung cancer based on bioinformatic strategy and human samples. PMID:33186389
Molecular pathophysiology of diabetes mellitus during pregnancy with antenatal complications. PMID:33184417
Chronic Disruption of the Late Cholesterol Synthesis Leads to Female-Prevalent Liver Cancer. PMID:33182326
LL-37-Induced Autophagy Contributed to the Elimination of Live Porphyromonas gingivalis Internalized in Keratinocytes. PMID:33178622
OMA orthology in 2021: website overhaul, conserved isoforms, ancestral gene order and more. PMID:33174605
Pan-transcriptome-based candidate therapeutic discovery for idiopathic pulmonary fibrosis. PMID:33167785
Potential roles of PBRM1 on immune infiltration in cholangiocarcinoma. PMID:33165423
Inhibition of AURKB, regulated by pseudogene MTND4P12, confers synthetic lethality to PARP inhibition in skin cutaneous melanoma. PMID:33163283
Network Pharmacology-Based Study on the Mechanism of Scutellariae Radix for Hepatocellular Carcinoma Treatment. PMID:33163086
HCK can serve as novel prognostic biomarker and therapeutic target for Breast Cancer patients. PMID:33162805
Identification of NLRP3 Inflammation-Related Gene Promoter Hypomethylation in Diabetic Retinopathy. PMID:33156339
Non-invasive Embryo Assessment: Altered Individual Protein Profile in Spent Culture Media from Embryos Transferred at Day 5. PMID:33151525
Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow. PMID:33149111
Dissecting Herpes Simplex Virus 1-Induced Host Shutoff at the RNA Level. PMID:33148793
Network pharmacology for the identification of phytochemicals in traditional Chinese medicine for COVID-19 that may regulate interleukin-6. PMID:33146673
Comprehensive Gene Expression Analysis Detects Global Reduction of Proteasome Subunits in Schizophrenia. PMID:33141894
ACE2 Netlas: In-silico functional characterization and drug-gene interactions of ACE2 gene network to understand its potential involvement in COVID-19 susceptibility. PMID:33140059
TET1 Directs Chondrogenic Differentiation by Regulating SOX9 Dependent Activation of Col2a1 and Acan In Vitro. PMID:33134768
Network Pharmacology-Based Study on the Mechanism of Pinellia ternata in Asthma Treatment. PMID:33133221
Identification of Hub Genes Associated With Hepatocellular Carcinoma Using Robust Rank Aggregation Combined With Weighted Gene Co-expression Network Analysis. PMID:33133125
Chinese Medicine Huzhen Tongfeng Formula Effectively Attenuates Gouty Arthritis by Inhibiting Arachidonic Acid Metabolism and Inflammatory Mediators. PMID:33132756
Landscape of transcription and expression regulated by DNA methylation related to age of donor and cell passage in adipose-derived mesenchymal stem cells. PMID:33130636
Gonadotroph tumours with a low SF-1 labelling index are more likely to recur and are associated with enrichment of the PI3K-AKT pathway. PMID:33128255
Proteomics reveals the preliminary physiological states of the spotted seal (Phoca largha) pups. PMID:33127980
PAR-TERRA is the main contributor to telomeric repeat-containing RNA transcripts in normal and cancer mouse cells. PMID:33127860
Novel Modular Rhodopsins from Green Algae Hold Great Potential for Cellular Optogenetic Modulation Across the Biological Model Systems. PMID:33126644
Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore. PMID:33122293
OsteoBLAST: Computational Routine of Global Molecular Analysis Applied to Biomaterials Development. PMID:33117780
Identification and Validation of Novel Genes in Anaplastic Thyroid Carcinoma via Bioinformatics Analysis. PMID:33116838
Identification of Novel Therapeutic Molecular Targets in Inflammatory Bowel Disease by Using Genetic Databases. PMID:33116744
Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila. PMID:33116184
Designing high affinity target-binding peptides to HLA-E: a key membrane antigen of multiple myeloma. PMID:33115963
Increased E2F2 predicts poor prognosis in patients with HCC based on TCGA data. PMID:33115417
Comprehensive analysis of the expression of SLC30A family genes and prognosis in human gastric cancer. PMID:33110097
Differential immune gene expression associated with contemporary range expansion in two invasive rodents in Senegal. PMID:33106535
Integrated Microarray to Identify the Hub miRNAs and Constructed miRNA-mRNA Network in Neuroblastoma Via Bioinformatics Analysis. PMID:33104965
Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain. PMID:33101276
Identification of Hub Genes and Potential Molecular Mechanisms in Patients with HBV-Associated Acute Liver Failure. PMID:33100826
Rpb4 and Puf3 imprint and post-transcriptionally control the stability of a common set of mRNAs in yeast. PMID:33094674
Identification of DHX9 as a cell cycle regulated nucleolar recruitment factor for CIZ1. PMID:33093612
Systems pharmacology in combination with proteomics reveals underlying mechanisms of Xihuang pill against triple-negative breast cancer. PMID:33092442
Biological and Clinical Changes in a Pediatric Series Treated with Off-Label JAK Inhibitors. PMID:33092242
Aerobic Exercises Induce Antioxidant Pathways Activation in Rats. PMID:33088472
Integrated Proteomic and Glycoproteomic Characterization of Human High-Grade Serous Ovarian Carcinoma. PMID:33086064
Genome-wide identification of Streptococcus sanguinis fitness genes in human serum and discovery of potential selective drug targets. PMID:33084151
Identification of Key Genes Involved in Acute Myocardial Infarction by Comparative Transcriptome Analysis. PMID:33083450
CKS2 and RMI2 are two prognostic biomarkers of lung adenocarcinoma. PMID:33083148
Examining the effector mechanisms of Xuebijing injection on COVID-19 based on network pharmacology. PMID:33082858
A computational and bioinformatic analysis of ACE2: an elucidation of its dual role in COVID-19 pathology and finding its associated partners as potential therapeutic targets. PMID:33073716
Cell Development Deficiency and Gene Expression Dysregulation of Trisomy 21 Retina Revealed by Single-Nucleus RNA Sequencing. PMID:33072724
Identification of key genes unique to the luminal a and basal-like breast cancer subtypes via bioinformatic analysis. PMID:33066779
Beneficial Effects of Naringenin in Cigarette Smoke-Induced Damage to the Lung Based on Bioinformatic Prediction and In Vitro Analysis. PMID:33066647
A practical guide to mechanistic systems modeling in biology using a logic-based approach. PMID:33064138
Transcription Factor Profiling Identifies Spatially Heterogenous Mediators of Follicular Thyroid Cancer Invasion. PMID:33063251
Identification of an 8-miRNA signature as a potential prognostic biomarker for glioma. PMID:33062427
The Perspective of Diagnostic and Prognostic Values of Lipoxygenases mRNA Expression in Colon Adenocarcinoma. PMID:33061426
A network pharmacology-based approach to explore potential targets of Caesalpinia pulcherima: an updated prototype in drug discovery. PMID:33057155
A strategy to incorporate prior knowledge into correlation network cutoff selection. PMID:33056991
IurV, Encoded by ORF VCA0231, Is Involved in the Regulation of Iron Uptake Genes in Vibrio cholerae. PMID:33053678
Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome. PMID:33052137
Circulating miR-1246 Targeting UBE2C, TNNI3, TRAIP, UCHL1 Genes and Key Pathways as a Potential Biomarker for Lung Adenocarcinoma: Integrated Biological Network Analysis. PMID:33050659
Early Pro-Inflammatory Remodeling of HDL Proteome in a Model of Diet-Induced Obesity: 2H2O-Metabolic Labeling-Based Kinetic Approach. PMID:33050482
SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways. PMID:33048956
Early-pregnancy transcriptome signatures of preeclampsia: from peripheral blood to placenta. PMID:33046794
Micro RNA Targets in HIV Latency: Insights into Novel Layers of Latency Control. PMID:33045840
Screening of autophagy genes as prognostic indicators for glioma patients. PMID:33042422
Identification and validation of an immune-related gene-based prognostic index for bladder cancer. PMID:33042413
RNA sequence analysis of dermal papilla cells' regeneration in 3D culture. PMID:33038058
Bioinformatic Identification of Potential Hub Genes in Muscle-Invasive Bladder Urothelial Carcinoma. PMID:33035117
Molecular evolutionary and structural analysis of human UCHL1 gene demonstrates the relevant role of intragenic epistasis in Parkinson's disease and other neurological disorders. PMID:33028204
Integration of anatomy ontology data with protein-protein interaction networks improves the candidate gene prediction accuracy for anatomical entities. PMID:33028186
A role for the MEGF6 gene in predisposition to osteoporosis. PMID:33026655
RNA oxidation in chromatin modification and DNA-damage response following exposure to formaldehyde. PMID:33024153
Functional relationships between recessive inherited genes and genes with de novo variants in autism spectrum disorder. PMID:33023636
Uncovering the protective mechanism of Taohong Siwu decoction against diabetic retinopathy via HIF-1 signaling pathway based on network analysis and experimental validation. PMID:33023593
Static Growth Promotes PrrF and 2-Alkyl-4(1H)-Quinolone Regulation of Type VI Secretion Protein Expression in Pseudomonas aeruginosa. PMID:33020221
Screening of key genes related to the prognosis of mouse sepsis. PMID:33015708
Guanxinshutong Alleviates Atherosclerosis by Suppressing Oxidative Stress and Proinflammation in ApoE-/- Mice. PMID:33014098
Identification of a Novel Immune-Related Prognostic Biomarker and Small-Molecule Drugs in Clear Cell Renal Cell Carcinoma (ccRCC) by a Merged Microarray-Acquired Dataset and TCGA Database. PMID:33014010
Localization of CDR2L and CDR2 in paraneoplastic cerebellar degeneration. PMID:33009713
Transcriptional landscape of the embryonic chicken Müllerian duct. PMID:33008304
Hyperconserved Elements in Human 5'UTRs Shape Essential Post-transcriptional Regulatory Networks. PMID:33005630
iMDA-BN: Identification of miRNA-disease associations based on the biological network and graph embedding algorithm. PMID:33005302
Exploring celiac disease candidate pathways by global gene expression profiling and gene network cluster analysis. PMID:33004927
Identification of putative master regulators in rheumatoid arthritis synovial fibroblasts using gene expression data and network inference. PMID:33004899
Sulforaphane-cysteine inhibited migration and invasion via enhancing mitophagosome fusion to lysosome in human glioblastoma cells. PMID:33004792
Multiple Isolated Transcription Factors Act as Switches and Contribute to Species Uniqueness. PMID:33003522
DeeplyEssential: a deep neural network for predicting essential genes in microbes. PMID:32998698
Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin. PMID:32994467
Identification of osteoporosis markers through bioinformatic functional analysis of serum proteome. PMID:32991410
PDX-derived organoids model in vivo drug response and secrete biomarkers. PMID:32990680
Comparative Transcriptomics and Co-Expression Networks Reveal Tissue- and Genotype-Specific Responses of qDTYs to Reproductive-Stage Drought Stress in Rice (Oryza sativa L.). PMID:32987927
Transcriptomic analyses of humans and mice provide insights into depression. PMID:32987454
Ionotropic Receptors as a Driving Force behind Human Synapse Establishment. PMID:32986821
The E3 ubiquitin-protein ligase MDM2 is a novel interactor of the von Hippel-Lindau tumor suppressor. PMID:32985545
Protein interactome mapping in Caenorhabditis elegans. PMID:32984658
Proteomics dataset of adult Anopheles Stephensi female brain. PMID:32984457
The Cardiac Syndecan-2 Interactome. PMID:32984315
Clinical Correlation of Wnt2 and COL8A1 With Colon Adenocarcinoma Prognosis. PMID:32983993
Therapeutic mechanism of Toujie Quwen granules in COVID-19 based on network pharmacology. PMID:32983259
Biogenesis of HLA Ligand Presentation in Immune Cells Upon Activation Reveals Changes in Peptide Length Preference. PMID:32983136
Inactivation of the Caenorhabditis elegans RNF-5 E3 ligase promotes IRE-1-independent ER functions. PMID:32981418
A Network Pharmacological Approach to Investigate the Mechanism of Action of Active Ingredients of Epimedii Herba and Their Potential Targets in Treatment of Alzheimer's Disease. PMID:32980851
Molecular Characterization of the Coproduced Extracellular Vesicles in HEK293 during Virus-Like Particle Production. PMID:32975947
Functional Disassociation Between the Protein Domains of MSMEG_4305 of Mycolicibacterium smegmatis (Mycobacterium smegmatis) in vivo. PMID:32973726
Differences in the Loin Tenderness of Iberian Pigs Explained through Dissimilarities in Their Transcriptome Expression Profile. PMID:32971875
Regulation of neuronal commitment in mouse embryonic stem cells by the Reno1/Bahcc1 locus. PMID:32969152
Identification of diagnostic and prognostic biomarkers, and candidate targeted agents for hepatitis B virus-associated early stage hepatocellular carcinoma based on RNA-sequencing data. PMID:32968453
Both Wnt signaling and epidermal stem cell-derived extracellular vesicles are involved in epidermal cell growth. PMID:32967725
Mapping Physiological ADP-Ribosylation Using Activated Ion Electron Transfer Dissociation. PMID:32966781
Identification of the DNA Replication Regulator MCM Complex Expression and Prognostic Significance in Hepatic Carcinoma. PMID:32964028
Analysis of key genes and pathways in breast ductal carcinoma in situ. PMID:32963623
Deciphering the Underlying Mechanism of Eucommiae Cortex against Osteoporotic Fracture by Network Pharmacology. PMID:32963568
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. PMID:32963231
Network Analysis Prioritizes DEWAX and ICE1 as the Candidate Genes for Major eQTL Hotspots in Seed Germination of Arabidopsis thaliana. PMID:32963085
Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease. PMID:32948616
miRNAs expression signature potentially associated with lymphatic dissemination in locally advanced prostate cancer. PMID:32948204
A network pharmacology study on analgesic mechanism of Yuanhu-Baizhi herb pair. PMID:32948176
Single-cell RNA-seq identifies unique transcriptional landscapes of human nucleus pulposus and annulus fibrosus cells. PMID:32943704
Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. PMID:32941599
Mechanisms of indigo naturalis on treating ulcerative colitis explored by GEO gene chips combined with network pharmacology and molecular docking. PMID:32938944
Identification and verification of three key genes associated with survival and prognosis of COAD patients via integrated bioinformatics analysis. PMID:32936304
Experimental evolution reveals nitrate tolerance mechanisms in Desulfovibrio vulgaris. PMID:32934357
Identification of Target Genes Related to Sulfasalazine in Triple-Negative Breast Cancer Through Network Pharmacology. PMID:32925871
Using bioinformatics and metabolomics to identify altered granulosa cells in patients with diminished ovarian reserve. PMID:32923184
Clinical significance of long non-coding RNA DUXAP8 and its protein coding genes in hepatocellular carcinoma. PMID:32922554
Exploring the Role of Chemokine Receptor 6 (Ccr6) in the BXD Mouse Model of Gulf War Illness. PMID:32922257
ANDDigest: a new web-based module of ANDSystem for the search of knowledge in the scientific literature. PMID:32921303
Multiple independent mechanisms link gene polymorphisms in the region of ZEB2 with risk of coronary artery disease. PMID:32919281
Cytokine Expression Pattern and Protein-Protein interaction network analysis of Leucocyte Rich Platelet Rich Fibrin and Injectable Form of Platelet Rich Fibrin. PMID:32915342
In silico identification of common and specific signatures in coronary heart diseases. PMID:32905032
Integrated PPI- and WGCNA-Retrieval of Hub Gene Signatures Shared Between Barrett's Esophagus and Esophageal Adenocarcinoma. PMID:32903837
Markers of Angiogenesis, Lymphangiogenesis, and Epithelial-Mesenchymal Transition (Plasticity) in CIN and Early Invasive Carcinoma of the Cervix: Exploring Putative Molecular Mechanisms Involved in Early Tumor Invasion. PMID:32899940
Short-Term Mild Temperature-Stress-Induced Alterations in the C. elegans Phosphoproteome. PMID:32899194
Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity. PMID:32898175
Prediction of drug-target interactions from multi-molecular network based on LINE network representation method. PMID:32894154
Mass spectrometry-based analysis of formalin-fixed, paraffin-embedded distal cholangiocarcinoma identifies stromal thrombospondin-2 as a potential prognostic marker. PMID:32887625
Identification of dysregulated miRNAs-genes network in ovarian cancer: An integrative approach to uncover the molecular interactions and oncomechanisms. PMID:32886452
Identification of potential biomarkers and candidate small molecule drugs in glioblastoma. PMID:32874133
Bioinformatics analysis of microRNA linked to ubiquitin proteasome system in traumatic osteonecrosis of the femoral head. PMID:32872046
Hypoxia regulates GR function through multiple mechanisms involving microRNAs 103 and 107. PMID:32871225
Exploring the stage-specific roles of Tcf-1 in T cell development and malignancy at single-cell resolution. PMID:32868912
Genomic landscape of the immune microenvironments of brain metastases in breast cancer. PMID:32867782
Music-listening regulates human microRNA expression. PMID:32867562
Network pharmacology reveals the multiple mechanisms of Xiaochaihu decoction in the treatment of non-alcoholic fatty liver disease. PMID:32863886
Genetics meets proteomics: perspectives for large population-based studies. PMID:32860016
Whole-transcriptome Analysis of Fully Viable Energy Efficient Glycolytic-null Cancer Cells Established by Double Genetic Knockout of Lactate Dehydrogenase A/B or Glucose-6-Phosphate Isomerase. PMID:32859627
Immiscible inclusion bodies formed by polyglutamine and poly(glycine-alanine) are enriched with distinct proteomes but converge in proteins that are risk factors for disease and involved in protein degradation. PMID:32857759
miR-29b enhances the proliferation and migration of bone marrow mesenchymal stem cells in rats with castration-induced osteoporosis through the PI3K/AKT and TGF-β/Smad signaling pathways. PMID:32855687
Circadian clock mechanism driving mammalian photoperiodism. PMID:32855407
Determining the interaction status and evolutionary fate of duplicated homomeric proteins. PMID:32853212
Anticancer Effects of Fufang Yiliu Yin Formula on Colorectal Cancer Through Modulation of the PI3K/Akt Pathway and BCL-2 Family Proteins. PMID:32850824
Study on Intervention Mechanism of Yiqi Huayu Jiedu Decoction on ARDS Based on Network Pharmacology. PMID:32849901
Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma. PMID:32849813
Screening and Identification of Therapeutic Targets for Pulmonary Arterial Hypertension Through Microarray Technology. PMID:32849793
Perturbation-based gene regulatory network inference to unravel oncogenic mechanisms. PMID:32843692
Genetic control of temperament traits across species: association of autism spectrum disorder risk genes with cattle temperament. PMID:32842956
Comparative analyses of alphaviral RNA:Protein complexes reveals conserved host-pathogen interactions. PMID:32841293
Whole-genome sequencing and gene network modules predict gemcitabine/carboplatin-induced myelosuppression in non-small cell lung cancer patients. PMID:32839457
LAITOR4HPC: A text mining pipeline based on HPC for building interaction networks. PMID:32838742
Pseudomonas aeruginosa Presents Multiple Vital Changes in Its Proteome in the Presence of 3-Hydroxyphenylacetic Acid, a Promising Antimicrobial Agent. PMID:32832748
β-Catenin safeguards the ground state of mousepluripotency by strengthening the robustness of the transcriptional apparatus. PMID:32832621
Identification of a Transcription Factor-microRNA-Gene Coregulation Network in Meningioma through a Bioinformatic Analysis. PMID:32832554
Suppression of Dynamical Network Biomarker Signals at the Predisease State (Mibyou) before Metabolic Syndrome in Mice by a Traditional Japanese Medicine (Kampo Formula) Bofutsushosan. PMID:32831883
Features of alternative splicing in stomach adenocarcinoma and their clinical implication: a research based on massive sequencing data. PMID:32831016
An Abiotic Stress Responsive U-Box E3 Ubiquitin Ligase Is Involved in OsGI-Mediating Diurnal Rhythm Regulating Mechanism. PMID:32825403
Oxidant-Induced Alterations in the Adipocyte Transcriptome: Role of the Na,K-ATPase Oxidant Amplification Loop. PMID:32824688
Transcriptional Regulation Based on Network of Autophagy Identifies Key Genes and Potential Mechanisms in Human Osteoarthritis. PMID:32819149
Differentiation-dependent susceptibility of human muscle cells to Zika virus infection. PMID:32817655
The Integrated Analyses of Driver Genes Identify Key Biomarkers in Thyroid Cancer. PMID:32812852
Discovery of the possible mechanisms in kouyanqing granule for treatment of oral ulcers based on network pharmacology. PMID:32811507
Gene network in pulmonary tuberculosis based on bioinformatic analysis. PMID:32811479
Sphingosine Kinase 1 is Associated With Immune Cell-Related Gene Expressions in Human Breast Cancer. PMID:32810665
Transcriptome analysis of Aedes aegypti Aag2 cells in response to dengue virus-2 infection. PMID:32807211
Deciphering serous ovarian carcinoma histopathology and platinum response by convolutional neural networks. PMID:32807164
Identification of UBE2T as an independent prognostic biomarker for gallbladder cancer. PMID:32802166
S-Palmitoylation as a Functional Regulator of Proteins Associated with Cisplatin Resistance in Bladder Cancer. PMID:32792852
Independent replications and integrative analyses confirm TRANK1 as a susceptibility gene for bipolar disorder. PMID:32791513
Novel variants in women with premature ovarian function decline identified via whole-exome sequencing. PMID:32789750
Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology. PMID:32788624
Gcn5p and Ubp8p Affect Protein Ubiquitylation and Cell Proliferation by Altering the Fermentative/Respiratory Flux Balance in Saccharomyces cerevisiae. PMID:32788380
Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane. PMID:32788342
Combining Neurobehavioral Analysis and In Vivo Photoaffinity Labeling to Understand Protein Targets of Methamphetamine in Casper Zebrafish. PMID:32786314
Identification of prognostic biomarkers associated with stromal cell infiltration in muscle-invasive bladder cancer by bioinformatics analyses. PMID:32786144
Salivary proteotypes of gingivitis tolerance and resilience. PMID:32777086
Functional Molecular Network Analysis Enables Prediction of Response to Vedolizumab Therapy in Anti-TNF Refractory IBD Patients. PMID:32776006
Population-scale proteome variation in human induced pluripotent stem cells. PMID:32773033
Anthraquinone Derivatives as an Immune Booster and their Therapeutic Option Against COVID-19. PMID:32772313
Global multi-omics and systems pharmacological strategy unravel the multi-targeted therapeutic potential of natural bioactive molecules against COVID-19: An in silico approach. PMID:32771622
Graph2GO: a multi-modal attributed network embedding method for inferring protein functions. PMID:32770210
Network-based modeling of drug effects on disease module in systemic sclerosis. PMID:32770109
Identification of DGUOK-AS1 as a Prognostic Factor in Breast Cancer by Bioinformatics Analysis. PMID:32766141
Analysis of the Antifungal Properties of Bacillus velezensis B-4 Through a Bioassay and Complete-Genome Sequencing. PMID:32765583
Elevated mRNA Expression Levels of NCAPG are Associated with Poor Prognosis in Ovarian Cancer. PMID:32765080
Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture. PMID:32762496
[Comparative analysis of structural characteristics and epitopes in S proteins between SARS-CoV-2 and SARS-CoV]. PMID:32762171
[Quantitative determination and optimun extraction technique of nine compounds of Paeoniae Radix Alba]. PMID:32762162
FLUTE: Fast and reliable knowledge retrieval from biomedical literature. PMID:32761077
Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach. PMID:32760426
Comparative gene expression profiling between optic nerve and spinal cord injury in Xenopus laevis reveals a core set of genes inherent in successful regeneration of vertebrate central nervous system axons. PMID:32758133
Gene expression-based clinical predictions in lung adenocarcinoma. PMID:32756002
Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer. PMID:32754443
MicroRNA Expression Signature in Mild Cognitive Impairment Due to Alzheimer's Disease. PMID:32737762
Promoter Proximal Pausing Limits Tumorous Growth Induced by the Yki Transcription Factor in Drosophila. PMID:32737120
Genome-Wide Screen for Context-Dependent Tumor Suppressors Identified Using in Vivo Models for Neoplasia in Drosophila. PMID:32737065
Network perturbation analysis in human bronchial epithelial cells following SARS-CoV2 infection. PMID:32735892
Extracellular Vesicles Produced by the Probiotic Propionibacterium freudenreichii CIRM-BIA 129 Mitigate Inflammation by Modulating the NF-κB Pathway. PMID:32733422
Verification of a Blood-Based Targeted Proteomics Signature for Malignant Pleural Mesothelioma. PMID:32732250
Integrative Analysis of Gene Expression and Regulatory Network Interaction Data Reveals the Protein Kinase C Family of Serine/Threonine Receptors as a Significant Druggable Target for Parkinson's Disease. PMID:32728898
Integrated bioinformatics analysis to decipher molecular mechanism of compound Kushen injection for esophageal cancer by combining WGCNA with network pharmacology. PMID:32728182
The identification of nuclear αvβ3 integrin in ovarian cancer: non-paradigmal localization with cancer promoting actions. PMID:32728020
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR-mutant gliomas. PMID:32727536
Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA. PMID:32726614
A Network-Based Approach to Explore the Mechanism and Bioactive Compounds of Erzhi Pill against Metabolic Dysfunction-Associated Fatty Liver Disease. PMID:32724826
Identification of glioblastoma-specific prognostic biomarkers via an integrative analysis of DNA methylation and gene expression. PMID:32724403
Integrated bioinformatics analysis for the identification of potential key genes affecting the pathogenesis of clear cell renal cell carcinoma. PMID:32724399
Identification of prognosis-related genes and construction of multi-regulatory networks in pancreatic cancer microenvironment by bioinformatics analysis. PMID:32724299
Identification of potential hub genes associated with the pathogenesis and prognosis of hepatocellular carcinoma via integrated bioinformatics analysis. PMID:32722976
Whole exome profiling and mutational analysis of Ocular Surface Squamous Neoplasia. PMID:32717381
Cancer-Testis Gene Expression in Hepatocellular Carcinoma: Identification of Prognostic Markers and Potential Targets for Immunotherapy. PMID:32715976
Identifying hub genes of papillary thyroid carcinoma in the TCGA and GEO database using bioinformatics analysis. PMID:32714651
The Delivery of Multipotent Adult Progenitor Cells to Extended Criteria Human Donor Livers Using Normothermic Machine Perfusion. PMID:32714318
Integrated Analysis of Three Publicly Available Gene Expression Profiles Identified Genes and Pathways Associated with Clear Cell Renal Cell Carcinoma. PMID:32712616
Computational Analysis of the Global Effects of Ly6E in the Immune Response to Coronavirus Infection Using Gene Networks. PMID:32708319
Effects of Egr1 on pancreatic acinar intracellular trypsinogen activation and the associated ceRNA network. PMID:32705196
Polyvalent therapeutic vaccine for type 2 diabetes mellitus: Immunoinformatics approach to study co-stimulation of cytokines and GLUT1 receptors. PMID:32703184
hsa-miR-106b-5p participates in the development of chronic thromboembolic pulmonary hypertension via targeting matrix metalloproteinase 2. PMID:32699607
Scalable phylogenetic profiling using MinHash uncovers likely eukaryotic sexual reproduction genes. PMID:32697802
Comprehensive Study of Different Expressed Genes and Their Functional Modules in Anesthesia for Off-Pump Coronary Artery Bypass Grafting. PMID:32695821
Topological and system-level protein interaction network (PIN) analyses to deduce molecular mechanism of curcumin. PMID:32694520
Mechanisms of Spica Prunellae against thyroid-associated Ophthalmopathy based on network pharmacology and molecular docking. PMID:32689994
Identification of Key Genes and Pathways Associated With Irradiation in Breast Cancer Tissue and Breast Cancer Cell Lines. PMID:32684870
Network-based identification of biomarkers for colon adenocarcinoma. PMID:32680494
Protein-Protein interactions uncover candidate 'core genes' within omnigenic disease networks. PMID:32678846
Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach. PMID:32678143
Streptococcus pneumoniae metal homeostasis alters cellular metabolism. PMID:32676626
Drug Repositioning for Noonan and LEOPARD Syndromes by Integrating Transcriptomics With a Structure-Based Approach. PMID:32676024
The Differential Phosphorylation-Dependent Signaling and Glucose Immunometabolic Responses Induced during Infection by Salmonella Enteritidis and Salmonella Heidelberg in Chicken Macrophage-like cells. PMID:32674261
The genetic factors of bilaterian evolution. PMID:32672535
Screening and identification of biomarkers associated with the diagnosis and prognosis of lung adenocarcinoma. PMID:32672359
Sulfoxide-Containing Polymer-Coated Nanoparticles Demonstrate Minimal Protein Fouling and Improved Blood Circulation. PMID:32670765
Analyzing Functional Pathways and constructing gene-gene network for Narcolepsy based on candidate genes. PMID:32669953
Inhibition of NF-κB Signaling Alters Acute Myelogenous Leukemia Cell Transcriptomics. PMID:32664684
Characterization of ASR gene and its role in drought tolerance in chickpea (Cicer arietinum L.). PMID:32663226
miR-499a promotes PANC-1 cell proliferation by down-regulating PDCD4 expression in pancreatic ductal adenocarcinoma. PMID:32661474
Network Analysis Identifies Gene Regulatory Network Indicating the Role of RUNX1 in Human Intervertebral Disc Degeneration. PMID:32659941
Harnessing endophenotypes and network medicine for Alzheimer's drug repurposing. PMID:32656864
Investigation of microbial community interactions between Lake Washington methanotrophs using -------genome-scale metabolic modeling. PMID:32655999
The Pre-Implantation Embryo Induces Uterine Inflammatory Reaction in Mice. PMID:32651899
Underlying Mechanism of Insulin Resistance: A Bioinformatics Analysis Based on Validated Related-Genes from Public Disease Databases. PMID:32651353
Radiosensitization by Kinase Inhibition Revealed by Phosphoproteomic Analysis of Pancreatic Cancer Cells. PMID:32651227
Comparative transcriptomic analysis identifies distinct molecular signatures and regulatory networks of chondroclasts and osteoclasts. PMID:32650826
Ecological Sensing Through Taste and Chemosensation Mediates Inflammation: A Biological Anthropological Approach. PMID:32647890
Adaptation of plasticity to projected maximum temperatures and across climatically defined bioregions. PMID:32647058
Systematic Discovery of Short Linear Motifs Decodes Calcineurin Phosphatase Signaling. PMID:32645368
Overexpression of annexin A5 might guide the gemtuzumab ozogamicin treatment choice in patients with pediatric acute myeloid leukemia. PMID:32636939
Inflammatory pathway analytes predicting rapid cognitive decline in MCI stage of Alzheimer's disease. PMID:32634865
CD66b+ monocytes represent a proinflammatory myeloid subpopulation in cancer. PMID:32632664
Upregulated proteoglycan-related signaling pathways in fluid flow shear stress-treated podocytes. PMID:32628542
Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens. PMID:32627965
Integrated microarray analysis to identify potential biomarkers and therapeutic targets in dilated cardiomyopathy. PMID:32626989
Nine Genes Mediate the Therapeutic Effects of Iodine-131 Radiotherapy in Thyroid Carcinoma Patients. PMID:32626543
Application of cAMP-dependent catalytic subunit β (PRKACB) Low Expression in Predicting Worse Overall Survival: A Potential Therapeutic Target for Colorectal Carcinoma. PMID:32626531
Proteome analysis revealed the essential functions of protein phosphatase PP2A in the induction of Th9 cells. PMID:32620893
Deciphering the underlying mechanism of Xianlinggubao capsule against osteoporosis by network pharmacology. PMID:32620113
Protein profile of well-differentiated versus un-differentiated human bronchial/tracheal epithelial cells. PMID:32613119
Multiple Herpes Simplex Virus-1 (HSV-1) Reactivations Induce Protein Oxidative Damage in Mouse Brain: Novel Mechanisms for Alzheimer's Disease Progression. PMID:32610629
Computational analysis of microarray data of Arabidopsis thaliana challenged with Alternaria brassicicola for identification of key genes in Brassica. PMID:32607787
Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration. PMID:32605588
Weighted gene co-expression network analysis to define pivotal modules and genes in diabetic heart failure. PMID:32602534
Alignment of Cell Lineage Trees Elucidates Genetic Programs for the Development and Evolution of Cell Types. PMID:32599560
Identification of SPRR3 as a novel diagnostic/prognostic biomarker for oral squamous cell carcinoma via RNA sequencing and bioinformatic analyses. PMID:32596058
Temperature Dramatically Shapes Mosquito Gene Expression With Consequences for Mosquito-Zika Virus Interactions. PMID:32595607
System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion. PMID:32589689
Minichromosome maintenance 6 complex component identified by bioinformatics analysis and experimental validation in esophageal squamous cell carcinoma. PMID:32583000
Disease Activity-Associated Alteration of mRNA m5 C Methylation in CD4+ T Cells of Systemic Lupus Erythematosus. PMID:32582707
Prediction of Drug-Target Interactions From Multi-Molecular Network Based on Deep Walk Embedding Model. PMID:32582646
Comprehensive Analysis of Key Genes and Regulatory Elements in Osteosarcoma Affected by Bone Matrix Mineral With Prognostic Values. PMID:32582282
Bioinformatics Analysis of Prognostic miRNA Signature and Potential Critical Genes in Colon Cancer. PMID:32582275
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant. PMID:32581705
Comprehensive Transcriptomic Analysis and Experimental Validation Identify lncRNA HOXA-AS2/miR-184/COL6A2 as the Critical ceRNA Regulation Involved in Low-Grade Glioma Recurrence. PMID:32581558
Decellularized skeletal muscles display neurotrophic effects in three-dimensional organotypic cultures. PMID:32578968
Comprehensive Analysis of Candidate Diagnostic and Prognostic Biomarkers Associated with Lung Adenocarcinoma. PMID:32578582
Caveolin-1 Ablation Imparts Partial Protection Against Inner Retinal Injury in Experimental Glaucoma and Reduces Apoptotic Activation. PMID:32578008
Bioinformatics Approach for Identifying Novel Biomarkers and Their Signaling Pathways Involved in Interstitial Cystitis/Bladder Pain Syndrome with Hunner Lesion. PMID:32575815
IFN-I Independent Antiviral Immune Response to Vesicular Stomatitis Virus Challenge in Mouse Brain. PMID:32575459
SLC1A1, SLC16A9, and CNTN3 Are Potential Biomarkers for the Occurrence of Colorectal Cancer. PMID:32566650
Silkworm pupae as source of high-value edible proteins and of bioactive peptides. PMID:32566182
Comprehensive characterization of driver genes in diffuse large B cell lymphoma. PMID:32565964
Random-forest algorithm based biomarkers in predicting prognosis in the patients with hepatocellular carcinoma. PMID:32565735
A novel prognostic signature of immune-related genes for patients with colorectal cancer. PMID:32564470
Impact of Phenol-Enriched Virgin Olive Oils on the Postprandial Levels of Circulating microRNAs Related to Cardiovascular Disease. PMID:32562310
Association of Dopamine Transporter Gene with Heroin Dependence in an Indian Subpopulation from Manipur. PMID:32557146
The bovine cumulus proteome is influenced by maturation condition and maturational competence of the oocyte. PMID:32555221
Putative circumsporozoite protein (CSP) of Plasmodium vivax is considerably distinct from the well-known CSP and plays a role in the protein ubiquitination pathway. PMID:32550551
Identification of Potential Key Genes for Pathogenesis and Prognosis in Prostate Cancer by Integrated Analysis of Gene Expression Profiles and the Cancer Genome Atlas. PMID:32547947
Identification of differentially expressed methylated genes in melanoma versus nevi using bioinformatics methods. PMID:32547879
MicroRNA-mRNA Co-sequencing Identifies Transcriptional and Post-transcriptional Regulatory Networks Underlying Muscle Wasting in Cancer Cachexia. PMID:32547603
Analysis of Virus and Host Proteomes During Productive HSV-1 and VZV Infection in Human Epithelial Cells. PMID:32547533
Identification of candidate aberrantly methylated and differentially expressed genes in Esophageal squamous cell carcinoma. PMID:32546690
Integrated analysis of a compendium of RNA-Seq datasets for splicing factors. PMID:32546682
De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2. PMID:32544884
The expression patterns and the diagnostic/prognostic roles of PTPN family members in digestive tract cancers. PMID:32536826
Comprehensive analysis of LDHAP5 pseudogene expression and potential pathogenesis in ovarian serous cystadenocarcinoma. PMID:32536817
Revealing the key point of the temperature stress response of Arthrospira platensis C1 at the interconnection of C- and N- metabolism by proteome analyses and PPI networking. PMID:32532219
Biophysical and Biochemical Characterization of Nascent Polypeptide-Associated Complex of Picrophilus torridus and Elucidation of Its Interacting Partners. PMID:32528429
PINOT: an intuitive resource for integrating protein-protein interactions. PMID:32527260
mTADA is a framework for identifying risk genes from de novo mutations in multiple traits. PMID:32522981
KRT8 and KRT19, associated with EMT, are hypomethylated and overexpressed in lung adenocarcinoma and link to unfavorable prognosis. PMID:32519739
Depolarization-dependent Induction of Site-specific Changes in Sialylation on N-linked Glycoproteins in Rat Nerve Terminals. PMID:32518069
Collapsing the list of myocardial infarction-related differentially expressed genes into a diagnostic signature. PMID:32517814
Downexpression of HSD17B6 correlates with clinical prognosis and tumor immune infiltrates in hepatocellular carcinoma. PMID:32514254
Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection. PMID:32514074
The Progression of Acute Myeloid Leukemia from First Diagnosis to Chemoresistant Relapse: A Comparison of Proteomic and Phosphoproteomic Profiles. PMID:32512867
Novel Comprehensive Bioinformatics Approaches to Determine the Molecular Genetic Susceptibility Profile of Moderate and Severe Asthma. PMID:32512817
Database Mining of Genes of Prognostic Value for the Prostate Adenocarcinoma Microenvironment Using the Cancer Gene Atlas. PMID:32509861
Fuling-Guizhi Herb Pair in Coronary Heart Disease: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation. PMID:32508942
Tamoxifen induces fatty liver disease in breast cancer through the MAPK8/FoxO pathway. PMID:32508033
A bioinformatics investigation into the pharmacological mechanisms of javanica oil emulsion injection in non-small cell lung cancer based on network pharmacology methodologies. PMID:32503508
microRNA-Dependent Modulation of Genes Contributes to ESR1's Effect on ERα Positive Breast Cancer. PMID:32500028
Excessive Homeostatic Gain in Spinal Motoneurons in a Mouse Model of Amyotrophic Lateral Sclerosis. PMID:32493926
The transcription factor E2A drives neural differentiation in pluripotent cells. PMID:32487737
Proteomic signatures of metronidazole-resistant Trichomonas vaginalis reveal novel proteins associated with drug resistance. PMID:32487244
miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology. PMID:32484539
Integrated omics in Drosophila uncover a circadian kinome. PMID:32483184
RNA-Binding Proteins Driving the Regulatory Activity of Small Non-coding RNAs in Bacteria. PMID:32478092
Bioinformatics Analysis based on Multiple Databases Identifies Hub Genes Associated with Hepatocellular Carcinoma. PMID:32476992
Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells. PMID:32470396
Identification and Verification of Core Genes in Colorectal Cancer. PMID:32462020
APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer's disease. PMID:32460813
Questing functions and structures of hypothetical proteins from Campylobacter jejuni: a computer-aided approach. PMID:32458979
Integration of Heterogeneous Experimental Data Improves Global Map of Human Protein Complexes. PMID:32457940
Identification of Prognostic miRNA Signature and Lymph Node Metastasis-Related Key Genes in Cervical Cancer. PMID:32457603
The Potential Mechanism of Wuwei Qingzhuo San against Hyperlipidemia Based on TCM Network Pharmacology and Validation Experiments in Hyperlipidemia Hamster. PMID:32454862
Revealing the Common Mechanisms of Scutellarin in Angina Pectoris and Ischemic Stroke Treatment via a Network Pharmacology Approach. PMID:32447519
Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation. PMID:32444791
Identification of crucial genes correlated with esophageal cancer by integrated high-throughput data analysis. PMID:32443386
Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker. PMID:32440005
The microbiome as a biosensor: functional profiles elucidate hidden stress in hosts. PMID:32438915
Virus-induced genetics revealed by multidimensional precision medicine transcriptional workflow applicable to COVID-19. PMID:32437232
Gene network analyses support subfunctionalization hypothesis for duplicated hsp70 genes in the Antarctic clam. PMID:32436134
Positive transcriptional response on inflammation and joint remodelling influenced by physical exercise in proteoglycan-induced arthritis: An animal study. PMID:32435454
Mass spectrometric analysis of the in vitro secretome from equine bone marrow-derived mesenchymal stromal cells to assess the effect of chondrogenic differentiation on response to interleukin-1β treatment. PMID:32434555
Comprehensive analysis of the value of RAB family genes in prognosis of breast invasive carcinoma. PMID:32432324
Dendritic Spine and Synaptic Plasticity in Alzheimer's Disease: A Focus on MicroRNA. PMID:32432108
Insights Into the Somatic Mutation Burden of Hepatoblastomas From Brazilian Patients. PMID:32432034
Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH. PMID:32429478
Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients - A Bioinformatics Approach. PMID:32426333
Post-translational Modification Crosstalk and Hotspots in Sirtuin Interactors Implicated in Cardiovascular Diseases. PMID:32425973
Identifying Drug Targets in Pancreatic Ductal Adenocarcinoma Through Machine Learning, Analyzing Biomolecular Networks, and Structural Modeling. PMID:32425783
Genome-Wide Analysis of the GRAS Gene Family in Barley (Hordeum vulgare L.). PMID:32423019
Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke. PMID:32419906
Integrated Analysis of the Mechanisms of Da-Chai-Hu Decoction in Type 2 Diabetes Mellitus by a Network Pharmacology Approach. PMID:32419835
Overexpression of SOX4 induces up-regulation of miR-126 and miR-195 in LNCaP prostate cancer cell line. PMID:32419068
miR-622 is a novel potential biomarker of breast carcinoma and impairs motility of breast cancer cells through targeting NUAK1 kinase. PMID:32418991
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1. PMID:32415096
CSN: unsupervised approach for inferring biological networks based on the genome alone. PMID:32414319
Comprehensive molecular characterization of circRNA-associated ceRNA network in constrictive pericarditis. PMID:32411772
The structure and reactivity of the HoxEFU complex from the cyanobacterium Synechocystis sp. PCC 6803. PMID:32409585
Blood transcriptome analysis reveals gene expression features of breast-feeding rhesus macaque ( Macaca mulatta) infants. PMID:32400975
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits. PMID:32400009
Identification of microRNA-mRNA regulatory networks and pathways related to retinoblastoma across human and mouse. PMID:32399402
Transcriptional analysis of the multiple Sry genes and developmental program at the onset of testis differentiation in the rat. PMID:32398044
Targeting Cellular Metabolism in Acute Myeloid Leukemia and The Role of Patient Heterogeneity. PMID:32392896
Genetic regulatory subnetworks and key regulating genes in rat hippocampus perturbed by prenatal malnutrition: implications for major brain disorders. PMID:32392183
Infection of Monocytes From Tuberculosis Patients With Two Virulent Clinical Isolates of Mycobacterium tuberculosis Induces Alterations in Myeloid Effector Functions. PMID:32391286
Influenza A virus directly modulates mouse eosinophil responses. PMID:32386457
Synovial Fluid Cell Proteomic Analysis Identifies Upregulation of Alpha-Taxilin Proteins in Rheumatoid Arthritis: A Potential Prognostic Marker. PMID:32377534
Serum omentin-1 level in patients with benign prostatic hyperplasia. PMID:32375790
The Integrated Landscape of Biological Candidate Causal Genes in Coronary Artery Disease. PMID:32373157
Human Alveolar and Splenic Macrophage Populations Display a Distinct Transcriptomic Response to Infection With Mycobacterium tuberculosis. PMID:32373118
Development of a new macrophage-specific TRAP mouse (MacTRAP) and definition of the renal macrophage translational signature. PMID:32372032
Senescent Stromal Cells Promote Cancer Resistance through SIRT1 Loss-Potentiated Overproduction of Small Extracellular Vesicles. PMID:32366480
miR-196B-5P and miR-200B-3P Are Differentially Expressed in Medulloblastomas of Adults and Children. PMID:32365560
Identification of Complex Rumen Microbiome Interaction Within Diverse Functional Niches as Mechanisms Affecting the Variation of Methane Emissions in Bovine. PMID:32362882
RNA-sequencing and microarray data mining revealing: the aberrantly expressed mRNAs were related with a poor outcome in the triple negative breast cancer patients. PMID:32355807
CPS1 expression and its prognostic significance in lung adenocarcinoma. PMID:32355785
Analysis of potential hub genes involved in the pathogenesis of Chinese type 1 diabetic patients. PMID:32355739
Integrated analysis of immunocyte infiltration and differential gene expression in tricuspid aortic valve-associated thoracic aortic aneurysms. PMID:32355729
Single-cell transcriptional networks in differentiating preadipocytes suggest drivers associated with tissue heterogeneity. PMID:32355218
Differential DNA Methylation Encodes Proliferation and Senescence Programs in Human Adipose-Derived Mesenchymal Stem Cells. PMID:32351540
Identification of Hub Genes Related to Carcinogenesis and Prognosis in Colorectal Cancer Based on Integrated Bioinformatics. PMID:32351322
High-throughput, Label-Free Quantitative Proteomic Studies of the Anticancer Effects of Electrical Pulses with Turmeric Silver Nanoparticles: an in vitro Model Study. PMID:32350346
A Comprehensive Proteomic and Phosphoproteomic Analysis of Retinal Pigment Epithelium Reveals Multiple Pathway Alterations in Response to the Inflammatory Stimuli. PMID:32344885
Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing. PMID:32341448
Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis. PMID:32339698
Proteomic analysis of the S. cerevisiae response to the anticancer ruthenium complex KP1019. PMID:32329475
Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas. PMID:32327612
HIV-1 and Amyloid Beta Remodel Proteome of Brain Endothelial Extracellular Vesicles. PMID:32326569
Red Chinese Cabbage Transcriptome Analysis Reveals Structural Genes and Multiple Transcription Factors Regulating Reddish Purple Color. PMID:32326209
Bioinformatics Methods for Mass Spectrometry-Based Proteomics Data Analysis. PMID:32326049
Identification of lung adenocarcinoma biomarkers based on bioinformatic analysis and human samples. PMID:32323809
Single‑cell RNA sequencing of t(8;21) acute myeloid leukemia for risk prediction. PMID:32323795
Integrated analysis of DNA methylation and transcriptome profiling of polycystic ovary syndrome. PMID:32323770
Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma. PMID:32321912
Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism. PMID:32320661
A precision medicine framework using artificial intelligence for the identification and confirmation of genomic biomarkers of response to an Alzheimer's disease therapy: Analysis of the blarcamesine (ANAVEX2-73) Phase 2a clinical study. PMID:32318621
Identification of Key Genes and the Pathophysiology Associated With Major Depressive Disorder Patients Based on Integrated Bioinformatics Analysis. PMID:32317989
MYC Controls the Epstein-Barr Virus Lytic Switch. PMID:32315601
Multi-level evidence of an allelic hierarchy of USH2A variants in hearing, auditory processing and speech/language outcomes. PMID:32313182
Predicting miRNA-disease association from heterogeneous information network with GraRep embedding model. PMID:32313121
Identification of HO-1 as a novel biomarker for graft acute cellular rejection and prognosis prediction after liver transplantation. PMID:32309368
Genome-wide single-nucleotide resolution of oxaliplatin-DNA adduct repair in drug-sensitive and -resistant colorectal cancer cell lines. PMID:32299912
A Systematic Way to Infer the Regulation Relations of miRNAs on Target Genes and Critical miRNAs in Cancers. PMID:32296462
USP22 promotes development of lung adenocarcinoma through ubiquitination and immunosuppression. PMID:32294625
ppiGReMLIN: a graph mining based detection of conserved structural arrangements in protein-protein interfaces. PMID:32293241
Gene Expression Profiles Identified Novel Urine Biomarkers for Diagnosis and Prognosis of High-Grade Bladder Urothelial Carcinoma. PMID:32292720
Quantitative Proteomics of Human Heart Samples Collected In Vivo Reveal the Remodeled Protein Landscape of Dilated Left Atrium Without Atrial Fibrillation. PMID:32291283
Tissue-specific epigenetic inheritance after paternal heat exposure in male wild guinea pigs. PMID:32285146
Identification of Key Genes and Pathways for Enchondromas by Bioinformatics Analysis. PMID:32284694
Design and analysis of CRISPR-Cas experiments. PMID:32284587
Bacterial colonization reprograms the neonatal gut metabolome. PMID:32284564
An RNA thermoswitch regulates daytime growth in Arabidopsis. PMID:32284544
DDX6 Helicase Behavior and Protein Partners in Human Adipose Tissue-Derived Stem Cells during Early Adipogenesis and Osteogenesis. PMID:32283676
Bioinformatics Analysis of the Expression of Key Long Intergenic Non-Protein Coding RNA Genes in Bladder Cancer. PMID:32277695
Genomics, molecular and evolutionary perspective of NAC transcription factors. PMID:32275733
Prediction of antiviral drugs against African swine fever viruses based on protein-protein interaction analysis. PMID:32274268
Oncogene inference optimization using constraint-based modelling incorporated with protein expression in normal and tumour tissues. PMID:32269785
Passenger Mutations Confound Phenotypes of SARM1-Deficient Mice. PMID:32268088
Characterization of Signaling Pathways Associated with Pancreatic β-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice. PMID:32265294
Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. PMID:32258954
Enhanced Inner-Ear Organoid Formation from Mouse Embryonic Stem Cells by Photobiomodulation. PMID:32258218
Al-induced proteomics changes in tomato plants over-expressing a glyoxalase I gene. PMID:32257229
Comparative Proteomic Investigation of Plasma Reveals Novel Potential Biomarker Groups for Acute Aortic Dissection. PMID:32256857
Network Pharmacology-Based Strategy for Predicting Therapy Targets of Traditional Chinese Medicine Xihuang Pill on Liver Cancer. PMID:32256653
An Integrated Pharmacology-Based Analysis for Antidepressant Mechanism of Chinese Herbal Formula Xiao-Yao-San. PMID:32256358
Hyperbolic Graph Convolutional Neural Networks. PMID:32256024
Nucleolin-Sle A Glycoforms as E-Selectin Ligands and Potentially Targetable Biomarkers at the Cell Surface of Gastric Cancer Cells. PMID:32252346
MAGIC: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data. PMID:32251445
Anticancer Effect of Radix Astragali on Cholangiocarcinoma In Vitro and Its Mechanism via Network Pharmacology. PMID:32246704
Effect of Transgenesis on mRNA and miRNA Profiles in Cucumber Fruits Expressing Thaumatin II. PMID:32245082
Network-Based Single-Cell RNA-Seq Data Imputation Enhances Cell Type Identification. PMID:32244427
Next-Generation Sequencing Analysis of Cellular Response to Influenza B Virus Infection. PMID:32244344
Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data. PMID:32243127
SCNrank: spectral clustering for network-based ranking to reveal potential drug targets and its application in pancreatic ductal adenocarcinoma. PMID:32241274
CDKN1A upregulation and cisplatin‑pemetrexed resistance in non‑small cell lung cancer cells. PMID:32236605
Transcriptome analysis reveals gender-specific differences in overall metabolic response of male and female patients in lung adenocarcinoma. PMID:32236130
Proteomic Profiles and Biological Processes of Relapsed vs. Non-Relapsed Pediatric Hodgkin Lymphoma. PMID:32235718
Introducing Critical Pain-related Genes: A System Biology Approach. PMID:32231777
Global expression and CpG methylation analysis of primary endothelial cells before and after TNFa stimulation reveals gene modules enriched in inflammatory and infectious diseases and associated DMRs. PMID:32231389
Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression. PMID:32231273
Computational Analysis of the Hypothetical Protein P9303_05031 from Marine Cyanobacterium Prochlorococcus Marinus MIT 9303. PMID:32229666
Identification of key gene modules and hub genes of human mantle cell lymphoma by coexpression network analysis. PMID:32219041
WGCNA analysis of the subcutaneous fat transcriptome in a novel tree shrew model. PMID:32216464
Weighted Gene Coexpression Network Analysis Identifies Specific Modules and Hub Genes Related to Major Depression. PMID:32214815
Bioinformatics analysis of vascular RNA-seq data revealed hub genes and pathways in a novel Tibetan minipig atherosclerosis model induced by a high fat/cholesterol diet. PMID:32213192
LncRNAs Predicted to Interfere With the Gene Regulation Activity of miR-637 and miR-196a-5p in GBM. PMID:32211330
Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation. PMID:32210974
Dimensionality reduction by UMAP to visualize physical and genetic interactions. PMID:32210240
ECE2 regulates neurogenesis and neuronal migration during human cortical development. PMID:32207244
The potential drug for treatment in pancreatic adenocarcinoma: a bioinformatical study based on distinct drug databases. PMID:32206083
Loss of the nuclear Wnt pathway effector TCF7L2 promotes migration and invasion of human colorectal cancer cells. PMID:32203164
Systems biology approaches based discovery of a small molecule inhibitor targeting both c-Met/PARP-1 and inducing cell death in breast cancer. PMID:32201536
Hyaluronidase-2 Regulates RhoA Signaling, Myofibroblast Contractility, and Other Key Profibrotic Myofibroblast Functions. PMID:32201263
An Integrated Meta-Analysis of Secretome and Proteome Identify Potential Biomarkers of Pancreatic Ductal Adenocarcinoma. PMID:32197468
Network-based computational approach to identify genetic links between cardiomyopathy and its risk factors. PMID:32196466
An array of 60,000 antibodies for proteome-scale antibody generation and target discovery. PMID:32195335
Comprehensive Computational Analysis of Protein Phenotype Changes Due to Plausible Deleterious Variants of Human SPTLC1 Gene. PMID:32195206
Novel candidate biomarkers of origin recognition complex 1, 5 and 6 for survival surveillance in patients with hepatocellular carcinoma. PMID:32194798
Integrated bioinformatics analysis of the association between apolipoprotein E expression and patient prognosis in papillary thyroid carcinoma. PMID:32194729
Prognostic value of key genes of the JAK-STAT signaling pathway in patients with cutaneous melanoma. PMID:32194688
Identification of candidate RNA signatures in triple-negative breast cancer by the construction of a competing endogenous RNA network with integrative analyses of Gene Expression Omnibus and The Cancer Genome Atlas data. PMID:32194687
Identification of crucial genes and pathways associated with colorectal cancer by bioinformatics analysis. PMID:32194683
Overexpression of miR-206 in osteosarcoma and its associated molecular mechanisms as assessed through TCGA and GEO databases. PMID:32194668
miRNA-Coordinated Schizophrenia Risk Network Cross-Talk With Cardiovascular Repair and Opposed Gliomagenesis. PMID:32194626
Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia. PMID:32192169
Mass-spectrometry-based draft of the Arabidopsis proteome. PMID:32188942
Potential therapies for residual hepatoblastoma following incomplete ablation treatment in a nude mouse subcutaneous xenograft model based on lncRNA and mRNA expression profiles. PMID:32186781
ICAM1 Regulates the Development of Gastric Cancer and May Be a Potential Biomarker for the Early Diagnosis and Prognosis of Gastric Cancer. PMID:32184657
Ependymoma Pediatric Brain Tumor Protein Fingerprinting by Integrated Mass Spectrometry Platforms: A Pilot Investigation. PMID:32183175
A multi-layered structure of the interphase chromocenter revealed by proximity-based biotinylation. PMID:32182352
Genes Involved in Stress Response and Especially in Phytoalexin Biosynthesis Are Upregulated in Four Malus Genotypes in Response to Apple Replant Disease. PMID:32180775
Integrated miRNA/mRNA Counter-Expression Analysis Highlights Oxidative Stress-Related Genes CCR7 and FOXO1 as Blood Markers of Coronary Arterial Disease. PMID:32178422
CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling. PMID:32171124
A learning based framework for diverse biomolecule relationship prediction in molecular association network. PMID:32170157
Network Pharmacology-based Research of Active Components of Albiziae Flos and Mechanisms of Its Antidepressant Effect. PMID:32166674
Mutation effect estimation on protein-protein interactions using deep contextualized representation learning. PMID:32166223
Forecasting risk gene discovery in autism with machine learning and genome-scale data. PMID:32165711
Caspase Recruitment Domain Containing Protein 9 Suppresses Non-Small Cell Lung Cancer Proliferation and Invasion via Inhibiting MAPK/p38 Pathway. PMID:32164050
Utilization of dried and long-term stored polyacrylamide gels for the advanced proteomic profiling of mitochondrial contact sites from rat liver. PMID:32161802
Screening and identification of critical biomarkers in erectile dysfunction: evidence from bioinformatic analysis. PMID:32161689
DNA methylation QTL analysis identifies new regulators of human longevity. PMID:32160291
Deep graph embedding for prioritizing synergistic anticancer drug combinations. PMID:32153729
Spatially distinct physiology of Bacteroides fragilis within the proximal colon of gnotobiotic mice. PMID:32152589
Hemispheric asymmetry in the human brain and in Parkinson's disease is linked to divergent epigenetic patterns in neurons. PMID:32151270
Network Pharmacology Study on the Pharmacological Mechanism of Cinobufotalin Injection against Lung Cancer. PMID:32148531
Promising key genes associated with tumor microenvironments and prognosis of hepatocellular carcinoma. PMID:32148377
Molecular pathology of human knee arthrofibrosis defined by RNA sequencing. PMID:32145378
Identification of the key genes and pathways involved in the tumorigenesis and prognosis of kidney renal clear cell carcinoma. PMID:32144299
A systematic analysis of natural α-glucosidase inhibitors from flavonoids of Radix scutellariae using ultrafiltration UPLC-TripleTOF-MS/MS and network pharmacology. PMID:32143602
Cooperation and interplay between base and nucleotide excision repair pathways: From DNA lesions to proteins. PMID:32141475
Identification of 2 Potential Core Genes for Influence of Gut Probiotics on Formation of Intracranial Aneurysms by Bioinformatics Analysis. PMID:32141441
KCML: a machine-learning framework for inference of multi-scale gene functions from genetic perturbation screens. PMID:32141232
Functionally Enigmatic Genes in Cancer: Using TCGA Data to Map the Limitations of Annotations. PMID:32139709
Proteomics-Based Detection of Immune Dysfunction in an Elite Adventure Athlete Trekking Across the Antarctica. PMID:32138228
Oral Microbiota Profile Associates with Sugar Intake and Taste Preference Genes. PMID:32138214
Epitranscriptomic 5-Methylcytosine Profile in PM2.5-induced Mouse Pulmonary Fibrosis. PMID:32135311
Inferring Causal Gene Regulatory Networks from Coupled Single-Cell Expression Dynamics Using Scribe. PMID:32135093
Identification of PTPRR and JAG1 as key genes in castration-resistant prostate cancer by integrated bioinformatics methods. PMID:32133801
BarleyNet: A Network-Based Functional Omics Analysis Server for Cultivated Barley, Hordeum vulgare L. PMID:32133024
Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension. PMID:32132543
Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases. PMID:32128391
Automated recognition of functional compound-protein relationships in literature. PMID:32126064
PHARMIP: An insilico method to predict genetics that underpin adverse drug reactions. PMID:32123669
Investigating the multi-target pharmacological mechanism of danhong injection acting on unstable angina by combined network pharmacology and molecular docking. PMID:32122353
Secretome Analysis Performed During in vitro Cardiac Differentiation: Discovering the Cardiac Microenvironment. PMID:32117977
Systemic Analysis of RNA Alternative Splicing Signals Related to the Prognosis for Head and Neck Squamous Cell Carcinoma. PMID:32117741
Transcriptomic and proteomic profiles of II YOU 838 (Oryza sativa) provide insights into heat stress tolerance in hybrid rice. PMID:32117601
Novel Combined Tissue Transcriptome Analysis After Lentogenic Newcastle Disease Virus Challenge in Inbred Chicken Lines of Differential Resistance. PMID:32117434
Pathogenic Gene Prediction Algorithm Based on Heterogeneous Information Fusion. PMID:32117433
An Investigation of the Mechanism of Rapid Relief of Ulcerative Colitis Induced by Five-flavor Sophora Flavescens Enteric-coated Capsules Based on Network Pharmacology. PMID:32116186
Large-scale Identification of N-linked Intact Glycopeptides in Human Serum using HILIC Enrichment and Spectral Library Search. PMID:32102970
Phosphotyrosine-based Phosphoproteomics for Target Identification and Drug Response Prediction in AML Cell Lines. PMID:32102969
Association of IL28B (IFNL3) rs12979860 mRNA levels, viral load, and liver function among HCV genotype 1a patients. PMID:32099617
Gallbladder cancer integrated bioinformatics analysis of protein profile data. PMID:32099604
SPD_1495 Contributes to Capsular Polysaccharide Synthesis and Virulence in Streptococcus pneumoniae. PMID:32098834
Horizontal Gene Transfer to a Defensive Symbiont with a Reduced Genome in a Multipartite Beetle Microbiome. PMID:32098813
High-Throughput Proteomics Enabled by a Photocleavable Surfactant. PMID:32097521
Impact of mutations in DNA methylation modification genes on genome-wide methylation landscapes and downstream gene activations in pan-cancer. PMID:32093698
Network-Based Genetic Profiling Reveals Cellular Pathway Differences Between Follicular Thyroid Carcinoma and Follicular Thyroid Adenoma. PMID:32093341
Comparative Proteomic Analysis of Wild-Type Physcomitrella Patens and an OPDA-Deficient Physcomitrella Patens Mutant with Disrupted PpAOS1 and PpAOS2 Genes after Wounding. PMID:32093080
Arginine in C9ORF72 Dipolypeptides Mediates Promiscuous Proteome Binding and Multiple Modes of Toxicity. PMID:32086375
Probing lncRNA-Protein Interactions: Data Repositories, Models, and Algorithms. PMID:32082358
A Network Pharmacology Approach to Estimate the Active Ingredients and Potential Targets of Cuscutae semen in the Treatment of Osteoporosis. PMID:32081843
Comparative in-silico proteomic analysis discerns potential granuloma proteins of Yersinia pseudotuberculosis. PMID:32080254
Differential Allele-Specific Expression Uncovers Breast Cancer Genes Dysregulated by Cis Noncoding Mutations. PMID:32078798
A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons. PMID:32075678
Heterogeneous Network Model to Identify Potential Associations Between Plasmodium vivax and Human Proteins. PMID:32075230
Changes in the proteome of sea urchin Paracentrotus lividus coelomocytes in response to LPS injection into the body cavity. PMID:32074628
Identification of core biomarkers associated with pathogenesis and prognostic outcomes of laryngeal squamous-cell cancer using bioinformatics analysis. PMID:32067095
A systematic integrative approach reveals novel microRNAs in diabetic nephropathy. PMID:32055241
STAT1 and its related molecules as potential biomarkers in Mycobacterium tuberculosis infection. PMID:32048448
Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication. PMID:32042151
Hierarchical cooperation of transcription factors from integration analysis of DNA sequences, ChIP-Seq and ChIA-PET data. PMID:32039697
TNFα-Signaling Modulates the Kinase Activity of Human Effector Treg and Regulates IL-17A Expression. PMID:32038615
Computational Identification of the Proteins Associated With Quorum Sensing and Biofilm Formation in Mycobacterium tuberculosis. PMID:32038515
Alpha-Synuclein Physiology and Pathology: A Perspective on Cellular Structures and Organelles. PMID:32038126
Integrative Network Analysis of Differentially Methylated and Expressed Genes for Biomarker Identification in Leukemia. PMID:32034170
Integrated characterisation of cancer genes identifies key molecular biomarkers in stomach adenocarcinoma. PMID:32034058
Combined Use of Three Machine Learning Modeling Methods to Develop a Ten-Gene Signature for the Diagnosis of Ventilator-Associated Pneumonia. PMID:32031163
Investigation of hub genes and their nonsynonymous single nucleotide polymorphism analysis in Plasmodium falciparum for designing therapeutic methodologies using next-generation sequencing approach. PMID:32029961
Phospho-PTM proteomic discovery of novel EPO- modulated kinases and phosphatases, including PTPN18 as a positive regulator of EPOR/JAK2 Signaling. PMID:32027948
A Global Screen for Assembly State Changes of the Mitotic Proteome by SEC-SWATH-MS. PMID:32027860
The RNA-Binding Protein ATXN2 is Expressed during Megakaryopoiesis and May Control Timing of Gene Expression. PMID:32024018
Radiation Therapy in Patients With Brain Cancer: Post-proteomics Interpretation. PMID:32021675
Study on the mechanisms of compound Kushen injection for the treatment of gastric cancer based on network pharmacology. PMID:32020871
Role of downregulated ADARB1 in lung squamous cell carcinoma. PMID:32016472
Screening and Identifying Immune-Related Cells and Genes in the Tumor Microenvironment of Bladder Urothelial Carcinoma: Based on TCGA Database and Bioinformatics. PMID:32010623
Altered molecular signatures during kidney development after intrauterine growth restriction of different origins. PMID:32008055
Knowledge-enhanced biomedical named entity recognition and normalization: application to proteins and genes. PMID:32000677
Postnatal development of skeletal muscle in pigs with intrauterine growth restriction: morphofunctional phenotype and molecular mechanisms. PMID:31997379
Transcriptome analysis of early pregnancy vitamin D status and spontaneous preterm birth. PMID:31995561
Key genes with prognostic values in suppression of osteosarcoma metastasis using comprehensive analysis. PMID:31992246
NAPAbench 2: A network synthesis algorithm for generating realistic protein-protein interaction (PPI) network families. PMID:31986158
Proteomic Analysis of Iodinated Contrast Agent-Induced Perturbation of Thyroid Iodide Uptake. PMID:31979418
Pulse-chase SILAC-based analyses reveal selective oversynthesis and rapid turnover of mitochondrial protein components of respiratory complexes. PMID:31974161
Reduced culture temperature attenuates oxidative stress and inflammatory response facilitating expansion and differentiation of adipose-derived stem cells. PMID:31973743
Combined proteomics/miRNomics of dendritic cell immunotherapy-treated glioblastoma patients as a screening for survival-associated factors. PMID:31969991
Biofilm formation displays intrinsic offensive and defensive features of Bacillus cereus. PMID:31969984
Integrated Analysis of Methylome and Transcriptome Changes Reveals the Underlying Regulatory Signatures Driving Curly Wool Transformation in Chinese Zhongwei Goats. PMID:31969898
Contribution of Known Genetic Risk Variants to Dyslipidemias and Type 2 Diabetes in Mexico: A Population-Based Nationwide Study. PMID:31968565
A Combined Proteomics, Metabolomics and In Vivo Analysis Approach for the Characterization of Probiotics in Large-Scale Production. PMID:31963736
Genome-Wide Investigation of Heat Shock Transcription Factor Family in Wheat (Triticum aestivum L.) and Possible Roles in Anther Development. PMID:31963482
Intragenic MicroRNAs Autoregulate Their Host Genes in Both Direct and Indirect Ways-A Cross-Species Analysis. PMID:31963421
CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual. PMID:31959876
Identification of dissociation factors in pancreatic Cancer using a mass spectrometry-based proteomic approach. PMID:31959150
Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle. PMID:31956366
Altered platelet proteome in lupus anticoagulant (LA)-positive patients-protein disulfide isomerase and NETosis as new players in LA-related thrombosis. PMID:31956273
Integrated Bioinformatics Analysis Identifies Hub Genes Associated with the Pathogenesis and Prognosis of Esophageal Squamous Cell Carcinoma. PMID:31950035
Comparative transcriptomics reveals candidate carotenoid color genes in an East African cichlid fish. PMID:31948394
Phosphatase POPX2 interferes with cell cycle by interacting with Chk1. PMID:31944151
Gigaxonin glycosylation regulates intermediate filament turnover and may impact giant axonal neuropathy etiology or treatment. PMID:31944090
Beneficial Effects of Bariatric Surgery-Induced by Weight Loss on the Proteome of Abdominal Subcutaneous Adipose Tissue. PMID:31941045
Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. PMID:31939735
Low Temperature Promotes Anthocyanin Biosynthesis and Related Gene Expression in the Seedlings of Purple Head Chinese Cabbage (Brassica rapa L.). PMID:31936856
Elevation of miR-191-5p level and its potential signaling pathways in hepatocellular carcinoma: a study validated by microarray and in-house qRT-PCR with 1,291 clinical samples. PMID:31933962
The clinical significance of CHEK1 in breast cancer: a high-throughput data analysis and immunohistochemical study. PMID:31933717
Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1. PMID:31932422
GDE3 regulates oligodendrocyte precursor proliferation via release of soluble CNTFRα. PMID:31932351
Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes. PMID:31925297
Integrative Construction and Analysis of Molecular Association Network in Human Cells by Fusing Node Attribute and Behavior Information. PMID:31923739
The Solute Carrier Family 2 Genes Are Potential Prognostic Biomarkers in Acute Myeloid Leukemia. PMID:31918632
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function. PMID:31915373
The MyoD family inhibitor domain-containing protein enhances the chemoresistance of cancer stem cells in the epithelial state by increasing β-catenin activity. PMID:31911618
Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival. PMID:31911546
Efficacy of FGFR Inhibitors and Combination Therapies for Acquired Resistance in FGFR2-Fusion Cholangiocarcinoma. PMID:31911531
A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria. PMID:31911436
Systems biology approaches toward autosomal dominant polycystic kidney disease (ADPKD). PMID:31907669
Protein Oxidative Damage in UV-Related Skin Cancer and Dysplastic Lesions Contributes to Neoplastic Promotion and Progression. PMID:31906275
Mapping axon initial segment structure and function by multiplexed proximity biotinylation. PMID:31900387
Sex-specific and opposite modulatory aspects revealed by PPI network and pathway analysis of ischemic stroke in humans. PMID:31899762
Identification of differentially expressed genes in the endothelial precursor cells of patients with type 2 diabetes mellitus by bioinformatics analysis. PMID:31897097
Utilizing network pharmacology to explore the underlying mechanism of Radix Salviae in diabetic retinopathy. PMID:31892939
An insight to HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) pathogenesis; evidence from high-throughput data integration and meta-analysis. PMID:31888669
Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation. PMID:31888456
Bioinformatic Analysis of Circular RNA-Associated ceRNA Network Associated with Hepatocellular Carcinoma. PMID:31886256
Identification of Key Genes and Pathways Associated with Sex Differences in Osteoarthritis Based on Bioinformatics Analysis. PMID:31886203
Study on the Multitarget Mechanism and Key Active Ingredients of Herba Siegesbeckiae and Volatile Oil against Rheumatoid Arthritis Based on Network Pharmacology. PMID:31885670
Transcriptional study of appetite regulating genes in the brain of zebrafish (Danio rerio) with impaired leptin signalling. PMID:31882937
RNA-seq and ChIP-seq as Complementary Approaches for Comprehension of Plant Transcriptional Regulatory Mechanism. PMID:31881735
Genome-Scale Metabolic Modeling with Protein Expressions of Normal and Cancerous Colorectal Tissues for Oncogene Inference. PMID:31881674
CLIC4 and CLIC1 bridge plasma membrane and cortical actin network for a successful cytokinesis. PMID:31879279
Microglial microRNAs mediate sex-specific responses to tau pathology. PMID:31873194
Exploring the Pharmacological Mechanism of the Herb Pair "HuangLian-GanJiang" against Colorectal Cancer Based on Network Pharmacology. PMID:31871473
Differential alternative splicing regulation among hepatocellular carcinoma with different risk factors. PMID:31856847
The Glycerol Phosphatase Gpp2: A Link to Osmotic Stress, Sulfur Assimilation and Virulence in Cryptococcus neoformans. PMID:31849880
Evaluating the consistency of large-scale pharmacogenomic studies. PMID:31846027
Src Kinase Is Biphosphorylated at Y416/Y527 and Activates the CUB-Domain Containing Protein 1/Protein Kinase C δ Pathway in a Subset of Triple-Negative Breast Cancers. PMID:31843498
BCL2 and hsa-miR-181a-5p are potential biomarkers associated with papillary thyroid cancer based on bioinformatics analysis. PMID:31842912
Ectopic expression of Medicago truncatula homeodomain finger protein, MtPHD6, enhances drought tolerance in Arabidopsis. PMID:31842738
Derivation of notochordal cells from human embryonic stem cells reveals unique regulatory networks by single cell-transcriptomics. PMID:31840817
The Western Diet Regulates Hippocampal Microvascular Gene Expression: An Integrated Genomic Analyses in Female Mice. PMID:31836762
Multi-omic Characterization of the Mode of Action of a Potent New Antimalarial Compound, JPC-3210, Against Plasmodium falciparum. PMID:31836637
Induction of PrMADS10 on the lower side of bent pine tree stems: potential role in modifying plant cell wall properties and wood anatomy. PMID:31831838
Changes in meta-transcriptome of rumen epimural microbial community and liver transcriptome in young calves with feed induced acidosis. PMID:31831817
SSIPe: accurately estimating protein-protein binding affinity change upon mutations using evolutionary profiles in combination with an optimized physical energy function. PMID:31830252
Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases. PMID:31827713
Co-expression analysis and ceRNA network reveal eight novel potential lncRNA biomarkers in hepatocellular carcinoma. PMID:31824761
Formal axioms in biomedical ontologies improve analysis and interpretation of associated data. PMID:31821406
Silencing of nuclear factor kappa b 1 gene expression inhibits colony formation, cell migration and invasion via the downregulation of interleukin 1 beta and matrix metallopeptidase 9 in renal cell carcinoma. PMID:31820316
Activation of ATM-c-IAP1 Pathway Mediates the Protective Effects of Estradiol in Human Vascular Endothelial Cells Exposed to Intermittent Hypoxia. PMID:31819689
Integrated Analysis To Identify Molecular Biomarkers Of High-Grade Serous Ovarian Cancer. PMID:31819501
Identification of molecular correlations of RBM8A with autophagy in Alzheimer's disease. PMID:31816601
Identification of potential core genes in metastatic renal cell carcinoma using bioinformatics analysis. PMID:31814889
Comprehensive analysis of vitreous chemokines involved in ischemic retinal vein occlusion. PMID:31814701
MELK is Upregulated in Advanced Clear Cell Renal Cell Carcinoma and Promotes Disease Progression by Phosphorylating PRAS40. PMID:31813279
Genome-Wide Distribution, Expression and Function Analysis of the U-Box Gene Family in Brassica oleracea L. PMID:31810369
Molecular Insights into miRNA-Driven Resistance to 5-Fluorouracil and Oxaliplatin Chemotherapy: miR-23b Modulates the Epithelial–Mesenchymal Transition of Colorectal Cancer Cells. PMID:31810268
Noteworthy prognostic value of phospholipase C delta genes in early stage pancreatic ductal adenocarcinoma patients after pancreaticoduodenectomy and potential molecular mechanisms. PMID:31808619
Reduced expression of microRNA-139-5p in hepatocellular carcinoma results in a poor outcome: An exploration the roles of microRNA-139-5p in tumorigenesis, advancement and prognosis at the molecular biological level using an integrated meta-analysis and bioinformatic investigation. PMID:31807180
MST4 Predicts Poor Prognosis And Promotes Metastasis By Facilitating Epithelial-Mesenchymal Transition In Gastric Cancer. PMID:31807065
Emerging Roles Of hsa-circ-0046600 Targeting The miR-640/HIF-1α Signalling Pathway In The Progression Of HCC. PMID:31807009
Systems pharmacology based approach to investigate the in-vivo therapeutic efficacy of Albizia lebbeck (L.) in experimental model of Parkinson's disease. PMID:31805998
Genome-Wide Analysis of Circular RNAs Mediated ceRNA Regulation in Porcine Embryonic Muscle Development. PMID:31803743
EGFR mutation: novel prognostic factor associated with immune infiltration in lower-grade glioma; an exploratory study. PMID:31801484
mitoXplorer, a visual data mining platform to systematically analyze and visualize mitochondrial expression dynamics and mutations. PMID:31799603
A Five-microRNA Signature as Prognostic Biomarker in Colorectal Cancer by Bioinformatics Analysis. PMID:31799184
Functional network analysis of gene-phenotype connectivity based on pioglitazone. PMID:31798704
LncRNA ZFAS1 serves as a prognostic biomarker to predict the survival of patients with ovarian cancer. PMID:31798702
Leveraging User-Friendly Network Approaches to Extract Knowledge From High-Throughput Omics Datasets. PMID:31798629
Modulatory Role of Vaginal-Isolated Lactococcus lactis on the Expression of miR-21, miR-200b, and TLR-4 in CAOV-4 Cells and In Silico Revalidation. PMID:31797280
Light chain amyloidosis induced inflammatory changes in cardiomyocytes and adipose-derived mesenchymal stromal cells. PMID:31796914
Text-mining clinically relevant cancer biomarkers for curation into the CIViC database. PMID:31796060
Peripheral blood mononuclear cell transcriptomes reveal an over-representation of down-regulated genes associated with immunity in HIV-exposed uninfected infants. PMID:31792230
Evaluation of colorectal cancer subtypes and cell lines using deep learning. PMID:31792061
Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system. PMID:31792058
Prognostic value and prospective molecular mechanism of miR-100-5p in hepatocellular carcinoma: A comprehensive study based on 1,258 samples. PMID:31788087
Cyclin-dependent kinase 9 expression and its association with CD8+ T cell infiltration in microsatellite-stable colorectal cancer. PMID:31788079
Identification of key genes and evaluation of clinical outcomes in lung squamous cell carcinoma using integrated bioinformatics analysis. PMID:31788059
Construction and Analysis of Molecular Association Network by Combining Behavior Representation and Node Attributes. PMID:31788002
LncDisAP: a computation model for LncRNA-disease association prediction based on multiple biological datasets. PMID:31787106
Integrating protein localization with automated signaling pathway reconstruction. PMID:31787091
Integrative analysis of the nuclear proteome in Pinus radiata reveals thermopriming coupled to epigenetic regulation. PMID:31781741
Clinical and Expression Significance of AKT1 by Co-expression Network Analysis in Endometrial Cancer. PMID:31781484
Identified the Synergistic Mechanism of Drynariae Rhizoma for Treating Fracture Based on Network Pharmacology. PMID:31781279
Effects of thyroid hormone on mitochondria and metabolism of human preimplantation embryos. PMID:31778245
Differentially expressed tRFs in CD5 positive relapsed & refractory diffuse large B cell lymphoma and the bioinformatic analysis for their potential clinical use. PMID:31775867
Transcriptomic and Co-Expression Network Profiling of Shoot Apical Meristem Reveal Contrasting Response to Nitrogen Rate between Indica and Japonica Rice Subspecies. PMID:31775351
Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress. PMID:31772688
Expression and potential prognostic value of histone family gene signature in breast cancer. PMID:31772649
Identification of cancer sex-disparity in the functional integrity of p53 and its X chromosome network. PMID:31772231
The FATTY ACID DESATURASE2 Family in Tomato Contributes to Primary Metabolism and Stress Responses. PMID:31767693
Exercise Exacerbates the Transcriptional Profile of Hypoxia, Oxidative Stress and Inflammation in Rats with Adjuvant-Induced Arthritis. PMID:31766745
GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors. PMID:31765370
Comparative analysis of differential proteome-wide protein-protein interaction network of Methanobrevibacter ruminantium M1. PMID:31763465
Genome Investigation of a Cariogenic Pathogen with Implications in Cardiovascular Diseases. PMID:31762508
Deciphering Molecular Virulence Mechanism of Mycobacterium tuberculosis Dop isopeptidase Based on Its Sequence-Structure-Function Linkage. PMID:31760575
A new model isolates glioblastoma clonal interactions and reveals unexpected modes for regulating motility, proliferation, and drug resistance. PMID:31758030
ENCORE: A Visualization Tool for Insight into Circadian Omics. PMID:31754663
Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response. PMID:31754133
Serum extracellular vesicles contain SPARC and LRG1 as biomarkers of colon cancer and differ by tumour primary location. PMID:31753726
Evaluation of Skin Response After Erbium:Yttrium- Aluminum-Garnet Laser Irradiation: A Network Analysis Approach. PMID:31749945
Genetic predisposition to mosaic Y chromosome loss in blood. PMID:31748747
NLRP3 inflammasome activation drives tau pathology. PMID:31748742
Identification of potential hub genes related to the progression and prognosis of hepatocellular carcinoma through integrated bioinformatics analysis. PMID:31746405
Metatranscriptomic Analysis of Multiple Environmental Stresses Identifies RAP2.4 Gene Associated with Arabidopsis Immunity to Botrytis cinerea. PMID:31740741
Prognostic Significance of CD276 in Non-small Cell Lung Cancer. PMID:31737785
Broad Substrate-Specific Phosphorylation Events Are Associated With the Initial Stage of Plant Cell Wall Recognition in Neurospora crassa. PMID:31736884
The Architecture of the Human RNA-Binding Protein Regulatory Network. PMID:31733516
Identification of the key differentially expressed genes and pathways involved in neutrophilia. PMID:31726910
Global Vectors Representation of Protein Sequences and Its Application for Predicting Self-Interacting Proteins with Multi-Grained Cascade Forest Model. PMID:31726752
Identifying candidate diagnostic markers for early stage of non-small cell lung cancer. PMID:31726467
Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart. PMID:31723062
[Bioinformatics analysis of programmed cell death ligand 1 co-expression genes and their regulatory network in head and neck squamous cell carcinoma]. PMID:31721500
An integrative methodology based on protein-protein interaction networks for identification and functional annotation of disease-relevant genes applied to channelopathies. PMID:31718537
RPGeNet v2.0: expanding the universe of retinal disease gene interactions network. PMID:31712826
Distinct cell proliferation, myogenic differentiation, and gene expression in skeletal muscle myoblasts of layer and broiler chickens. PMID:31712718
COPD-dependent effects of genetic variation in key inflammation pathway genes on lung cancer risk. PMID:31709530
Landscape of Loci and Candidate Genes for Muscle Fatty Acid Composition in Pigs Revealed by Multiple Population Association Analysis. PMID:31708975
Gene expression analysis of the cerebellar cortex in essential tremor. PMID:31707044
Integrated transcriptomic analysis reveals hub genes involved in diagnosis and prognosis of pancreatic cancer. PMID:31706267
Functional categorization of de novo transcriptome assembly of Vanilla planifolia Jacks. potentially points to a translational regulation during early stages of infection by Fusarium oxysporum f. sp. vanillae. PMID:31703622
Noninvasive Brain Stimulation Enhances Memory Acquisition and Is Associated with Synaptoneurosome Modification in the Rat Hippocampus. PMID:31699891
Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide. PMID:31695851
Global transcriptome analysis of rat hypothalamic arcuate nucleus demonstrates reversal of hypothalamic gliosis following surgically and diet induced weight loss. PMID:31695063
Understanding allergic multimorbidity within the non-eosinophilic interactome. PMID:31693680
Investigating Novel Genes Potentially Involved in Endometrial Adenocarcinoma using Next-Generation Sequencing and Bioinformatic Approaches. PMID:31692912
Differential gene expression analysis of HNSCC tumors deciphered tobacco dependent and independent molecular signatures. PMID:31692905
A network pharmacology approach to explore active compounds and pharmacological mechanisms of epimedium for treatment of premature ovarian insufficiency. PMID:31692519
Rapid Discovery of Potential Drugs for Osteonecrosis of Femoral Head Based on Gene Expression Omnibus Database and Connectivity Map. PMID:31692295
Anaerobic Transcription by OxyR: A Novel Paradigm for Nitrosative Stress. PMID:31691575
Melittin inhibits proliferation, migration and invasion of bladder cancer cells by regulating key genes based on bioinformatics and experimental assays. PMID:31691530
Co-regulation map of the human proteome enables identification of protein functions. PMID:31690884
Co-expression of synaptic genes in the sponge Amphimedon queenslandica uncovers ancient neural submodules. PMID:31673079
First genome-wide association study of non-severe malaria in two birth cohorts in Benin. PMID:31667592
8-OxoG in GC-rich Sp1 binding sites enhances gene transcription in adipose tissue of juvenile mice. PMID:31666587
ChlamDB: a comparative genomics database of the phylum Chlamydiae and other members of the Planctomycetes-Verrucomicrobiae-Chlamydiae superphylum. PMID:31665454
MaGenDB: a functional genomics hub for Malvaceae plants. PMID:31665439
Network inference with ensembles of bi-clustering trees. PMID:31660848
The miR-15a-5p-XIST-CUL3 regulatory axis is important for sepsis-induced acute kidney injury. PMID:31658856
Dynamic gene expression changes in response to micronutrient, macronutrient, and multiple stress exposures in soybean. PMID:31655948
Autologous micrograft accelerates endogenous wound healing response through ERK-induced cell migration. PMID:31654035
Hypergraph-based connectivity measures for signaling pathway topologies. PMID:31652258
Accelerated evolution and diversifying selection drove the adaptation of cetacean bone microstructure. PMID:31651232
Integrated Analysis of Brain Transcriptome Reveals Convergent Molecular Pathways in Autism Spectrum Disorder. PMID:31649562
Calcium-signaling proteins mediate the plant transcriptomic response during a well-established Xanthomonas campestris pv. campestris infection. PMID:31645958
Modeling cancer drug response through drug-specific informative genes. PMID:31645597
SilkDB 3.0: visualizing and exploring multiple levels of data for silkworm. PMID:31642484
Mapping genetic interactions in cancer: a road to rational combination therapies. PMID:31640753
HMNPPID-human malignant neoplasm protein-protein interaction database. PMID:31639057
β‑elemene inhibits the generation of peritoneum effusion in pancreatic cancer via suppression of the HIF1A‑VEGFA pathway based on network pharmacology. PMID:31638231
The long non-coding RNA GHSROS facilitates breast cancer cell migration and orthotopic xenograft tumour growth. PMID:31638176
Analysis of "old" proteins unmasks dynamic gradient of cartilage turnover in human limbs. PMID:31633025
Expression profile of circular RNA s in TMJ osteoarthritis synovial tissues and potential functions of hsa_circ_0000448 with specific back-spliced junction. PMID:31632516
Differential secretome of pancreatic cancer cells in serum-containing conditioned medium reveals CCT8 as a new biomarker of pancreatic cancer invasion and metastasis. PMID:31632196
COL6A6 interacted with P4HA3 to suppress the growth and metastasis of pituitary adenoma via blocking PI3K-Akt pathway. PMID:31627190
Multi-strategic RNA-seq analysis reveals a high-resolution transcriptional landscape in cotton. PMID:31624240
Head and Neck Cancers Promote an Inflammatory Transcriptome through Coactivation of Classic and Alternative NF-κB Pathways. PMID:31624067
The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population. PMID:31622411
Identification of prognostic biomarkers for malignant melanoma using microarray datasets. PMID:31620197
RNA-Seq analysis of ileocecal valve and peripheral blood from Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis revealed dysregulation of the CXCL8/IL8 signaling pathway. PMID:31619718
PBK as a Potential Biomarker Associated with Prognosis of Glioblastoma. PMID:31617063
Increased expression of hub gene CXCL10 in peripheral blood mononuclear cells of patients with systemic lupus erythematosus. PMID:31616519
MUDENG Expression Profiling in Cohorts and Brain Tumor Biospecimens to Evaluate Its Role in Cancer. PMID:31616474
Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1. PMID:31615982
An SNP-Based Genetic Map and QTL Mapping for Growth Traits in the Red-Spotted Grouper (Epinephelus akaara). PMID:31614822
Identification of candidate genes for the diagnosis and treatment of cholangiocarcinoma using a bioinformatics approach. PMID:31612054
Evaluation of the target genes of arsenic trioxide in pancreatic cancer by bioinformatics analysis. PMID:31612027
IRF2 is a master regulator of human keratinocyte stem cell fate. PMID:31611556
Data Integration in Poplar: 'Omics Layers and Integration Strategies. PMID:31608114
Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation. PMID:31607918
The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. PMID:31607563
A comprehensive expression landscape of RNA-binding proteins (RBPs) across 16 human cancer types. PMID:31607220
Diagnostic and prognostic biomarkers of Human Leukocyte Antigen complex for hepatitis B virus-related hepatocellular carcinoma. PMID:31602270
Dysregulated liver lipid metabolism and innate immunity associated with hepatic steatosis in neonatal BBdp rats and NOD mice. PMID:31601915
Investigating the Multi-Target Pharmacological Mechanism of Hedyotis diffusa Willd Acting on Prostate Cancer: A Network Pharmacology Approach. PMID:31600936
Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor. PMID:31599329
Comprehensive investigation of the clinical significance and molecular mechanisms of plasmacytoma variant translocation 1 in sarcoma using genome-wide RNA sequencing data. PMID:31598169
Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer's disease and dementia with Lewy bodies. PMID:31592314
CircUBAP2-mediated competing endogenous RNA network modulates tumorigenesis in pancreatic adenocarcinoma. PMID:31584877
Network Pharmacology Analysis of Traditional Chinese Medicine Formula Xiao Ke Yin Shui Treating Type 2 Diabetes Mellitus. PMID:31583009
The role of extracellular matrix in mouse and human corneal neovascularization. PMID:31582785
Identification of pivotal lncRNAs in papillary thyroid cancer using lncRNA-mRNA-miRNA ceRNA network analysis. PMID:31579562
A tailored approach to fusion transcript identification increases diagnosis of rare inherited disease. PMID:31577830
Proteomic characterization of primary cultured myocytes in a fish model at different myogenesis stages. PMID:31576009
HLA class I-restricted T cell epitopes isolated and identified from myeloid leukemia cells. PMID:31575892
Plant DNA Polymerases. PMID:31569730
Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells. PMID:31569627
Global transcriptional regulation of STAT3- and MYC-mediated sepsis-induced ARDS. PMID:31566109
Marine Natural Products and Drug Resistance in Latent Tuberculosis. PMID:31561525
Variations of Wnt/β-catenin pathway-related genes in susceptibility to knee osteoarthritis: A three-centre case-control study. PMID:31560818
Identification of root transcriptional responses to shoot illumination in Arabidopsis thaliana. PMID:31560104
Quantitative proteomic analysis of enhanced cellular effects of electrochemotherapy with Cisplatin in triple-negative breast cancer cells. PMID:31558821
Altered long noncoding RNA profile after intracerebral hemorrhage. PMID:31557399
Association study identified biologically relevant receptor genes with synergistic functions in celiac disease. PMID:31554915
Identification of Candidate Adaxial-Abaxial-Related Genes Regulating Petal Expansion During Flower Opening in Rosa chinensis "Old Blush". PMID:31552079
Proteomics of Crystal-Cell Interactions: A Model for Kidney Stone Research. PMID:31547429
Exploring the active mechanism of berberine against HCC by systematic pharmacology and experimental validation. PMID:31545468
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis. PMID:31536960
ATF4 destabilizes RET through nonclassical GRP78 inhibition to enhance chemosensitivity to bortezomib in human osteosarcoma. PMID:31534554
Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53. PMID:31534536
Widespread cis-regulatory convergence between the extinct Tasmanian tiger and gray wolf. PMID:31533979
Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients. PMID:31533822
The bioinformatics aspects of gene screening of HT-29, human colon cell line treated with caffeic acid. PMID:31528309
Identification of Novel Genes in Osteoarthritic Fibroblast-Like Synoviocytes Using Next-Generation Sequencing and Bioinformatics Approaches. PMID:31523167
Tandem RNA isolation reveals functional rearrangement of RNA-binding proteins on CDKN1B/p27Kip1 3'UTRs in cisplatin treated cells. PMID:31522610
Multifaceted protein-protein interaction prediction based on Siamese residual RCNN. PMID:31510705
Gene-set association and epistatic analyses reveal complex gene interaction networks affecting flowering time in a worldwide barley collection. PMID:31504706
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice. PMID:31504240
Proteomics approach to identify serum biomarkers associated with the progression of diabetes in Korean patients with abdominal obesity. PMID:31504048
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila. PMID:31498321
Sp1-induced upregulation of the long noncoding RNA TINCR inhibits cell migration and invasion by regulating miR-107/miR-1286 in lung adenocarcinoma. PMID:31497197
Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence. PMID:31495571
Function of low ADARB1 expression in lung adenocarcinoma. PMID:31491024
Prognostic value of Kinesin-4 family genes mRNA expression in early-stage pancreatic ductal adenocarcinoma patients after pancreaticoduodenectomy. PMID:31489986
The developmental origins of sex-biased expression in cardiac development. PMID:31488212
CFHR1 is a potentially downregulated gene in lung adenocarcinoma. PMID:31485643
Analysis of clinical significance and prospective molecular mechanism of main elements of the JAK/STAT pathway in hepatocellular carcinoma. PMID:31485610
Computer aided analysis of disease linked protein networks. PMID:31485137
The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation. PMID:31485003
Muscle transcriptome analysis reveals genes and metabolic pathways related to mineral concentration in Bos indicus. PMID:31481722
Benchmarking network propagation methods for disease gene identification. PMID:31479437
Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut. PMID:31477894
Identifying Hepatocellular Carcinoma Driver Genes by Integrative Pathway Crosstalk and Protein Interaction Network. PMID:31464520
WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. PMID:31462314
Tumor Transcriptome Reveals High Expression of IL-8 in Non-Small Cell Lung Cancer Patients with Low Pectoralis Muscle Area and Reduced Survival. PMID:31455042
A Novel Computational Model for Predicting microRNA-Disease Associations Based on Heterogeneous Graph Convolutional Networks. PMID:31455028
HTR1D, TIMP1, SERPINE1, MMP3 and CNR2 affect the survival of patients with colon adenocarcinoma. PMID:31452735
Identification of aberrantly methylated differentially expressed genes in glioblastoma multiforme and their association with patient survival. PMID:31452706
Transcriptome analysis to understand the effects of the toxoflavin and tropolone produced by phytopathogenic Burkholderia on Escherichia coli. PMID:31452043
In vivo evidence for a regulatory role of phosphorylation of Arabidopsis Rubisco activase at the Thr78 site. PMID:31451644
The RabGAP Gene Family in Tomato (Solanum lycopersicum) and Wild Relatives: Identification, Interaction Networks, and Transcriptional Analysis during Plant Development and in Response to Salt Stress. PMID:31450820
Development of a 21-miRNA Signature Associated With the Prognosis of Patients With Bladder Cancer. PMID:31448232
Transcriptomic Analysis Identifies RNA Binding Proteins as Putative Regulators of Myelopoiesis and Leukemia. PMID:31448224
Construction and Investigation of a lncRNA-Associated ceRNA Regulatory Network in Cholangiocarcinoma. PMID:31448221
Three Novel Players: PTK2B, SYK, and TNFRSF21 Were Identified to Be Involved in the Regulation of Bovine Mastitis Susceptibility via GWAS and Post-transcriptional Analysis. PMID:31447828
ComplexBrowser: A Tool for Identification and Quantification of Protein Complexes in Large-scale Proteomics Datasets. PMID:31447428
The Scs disulfide reductase system cooperates with the metallochaperone CueP in Salmonella copper resistance. PMID:31444272
Hamiltonian energy as an efficient approach to identify the significant key regulators in biological networks. PMID:31442253
Post-transcriptional Regulation of Colorectal Cancer: A Focus on RNA-Binding Proteins. PMID:31440515
Efficient Mining of Variants From Trios for Ventricular Septal Defect Association Study. PMID:31440271
Protein-Protein Interactions in Candida albicans. PMID:31440220
Time-Dependent Changes in Microglia Transcriptional Networks Following Traumatic Brain Injury. PMID:31440141
Insoluble solids at high concentrations repress yeast's response against stress and increase intracellular ROS levels. PMID:31439886
Multi-Omic Approaches Identify Metabolic and Autophagy Regulators Important in Ovarian Cancer Dissemination. PMID:31437751
ProtFus: A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins. PMID:31437145
Transcriptome profile of Corynebacterium pseudotuberculosis in response to iron limitation. PMID:31429699
Co-Expression Network Analysis Revealed That the ATP5G1 Gene Is Associated With Major Depressive Disorder. PMID:31428135
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex. PMID:31427770
PcG Proteins MSI1 and BMI1 Function Upstream of miR156 to Regulate Aerial Tuber Formation in Potato. PMID:31427464
A mechanistic evaluation of the angiogenic properties of a dehydrated amnion chorion membrane in vitro and in vivo. PMID:31425636
Identification of CFTR as a novel key gene in chromophobe renal cell carcinoma through bioinformatics analysis. PMID:31423244
Five genes may predict metastasis in non-small cell lung cancer using bioinformatics analysis. PMID:31423239
Integrated bioinformatics analysis to identify 15 hub genes in breast cancer. PMID:31423162
Identification of differentially expressed genes and signaling pathways in chronic obstructive pulmonary disease via bioinformatic analysis. PMID:31419078
Differential coexpression networks in bronchiolitis and emphysema phenotypes reveal heterogeneous mechanisms of chronic obstructive pulmonary disease. PMID:31419013
The regulation of the sulfur amino acid biosynthetic pathway in Cryptococcus neoformans: the relationship of Cys3, Calcineurin, and Gpp2 phosphatases. PMID:31417135
An integrative bioinformatics analysis of microarray data for identifying hub genes as diagnostic biomarkers of preeclampsia. PMID:31416885
Adult and iPS-derived non-parenchymal cells regulate liver organoid development through differential modulation of Wnt and TGF-β. PMID:31416480
Identifying crucial genes for prognosis in septic patients: Gene integration study based on PRISMA guidelines. PMID:31415393
HENA, heterogeneous network-based data set for Alzheimer's disease. PMID:31413325
Age modulates liver responses to asparaginase-induced amino acid stress in mice. PMID:31413113
Genotyping, generation and proteomic profiling of the first human autosomal dominant osteopetrosis type II-specific induced pluripotent stem cells. PMID:31412925
The liver proteome in a mouse model for Ascaris suum resistance and susceptibility: evidence for an altered innate immune response. PMID:31412915
The Retinal Ganglion Cell Transportome Identifies Proteins Transported to Axons and Presynaptic Compartments in the Visual System In Vivo. PMID:31412257
Identification of crucial genes based on expression profiles of hepatocellular carcinomas by bioinformatics analysis. PMID:31410310
Genome-wide Identification, Classification, Expression and Duplication Analysis of GRAS Family Genes in Juglans regia L. PMID:31406208
Construction and Comprehensive Analysis of a Molecular Association Network via lncRNA-miRNA -Disease-Drug-Protein Graph. PMID:31405040
Mass spectrometry-based proteomic techniques to identify cerebrospinal fluid biomarkers for diagnosing suspected central nervous system infections. A systematic review. PMID:31404562
KH-Type Splicing Regulatory Protein Controls Colorectal Cancer Cell Growth and Modulates the Tumor Microenvironment. PMID:31404541
The P2-receptor-mediated Ca2+ signalosome of the human pulmonary endothelium - implications for pulmonary arterial hypertension. PMID:31396838
Frailty in middle age is associated with frailty status and race-specific changes to the transcriptome. PMID:31395793
Characterization of cellular transcriptomic signatures induced by different respiratory viruses in human reconstituted airway epithelia. PMID:31391513
Landscape of the Plasmodium Interactome Reveals Both Conserved and Species-Specific Functionality. PMID:31390575
Comparison of Target Features for Predicting Drug-Target Interactions by Deep Neural Network Based on Large-Scale Drug-Induced Transcriptome Data. PMID:31382356
C-Jun drives melanoma progression in PTEN wild type melanoma cells. PMID:31378787
Upregulated Expression of CUX1 Correlates with Poor Prognosis in Glioma Patients: a Bioinformatic Analysis. PMID:31377983
Network Pharmacology-Based Pharmacological Mechanism of the Chinese Medicine Rhizoma drynariae Against Osteoporosis. PMID:31368456
Redox Systems Biology: Harnessing the Sentinels of the Cysteine Redoxome. PMID:31368359
Detection of dynamic protein complexes through Markov Clustering based on Elephant Herd Optimization Approach. PMID:31366992
CNS cell type-specific gene profiling of P301S tau transgenic mice identifies genes dysregulated by progressive tau accumulation. PMID:31366728
A High Protein Model Alters the Endometrial Transcriptome of Mares. PMID:31366166
Systems Network Genomic Analysis Reveals Cardioprotective Effect of MURC/Cavin-4 Deletion Against Ischemia/Reperfusion Injury. PMID:31364493
Bioactive Proteins in Channa striata Promote Wound Healing through Angiogenesis and Cell Proliferation. PMID:31362651
Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans. PMID:31358989
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases. PMID:31358043
Downregulation of STAT3, β-Catenin, and Notch-1 by Single and Combinations of siRNA Treatment Enhance Chemosensitivity of Wild Type and Doxorubicin Resistant MCF7 Breast Cancer Cells to Doxorubicin. PMID:31357721
Investigation of Precise Molecular Mechanistic Action of Tobacco-Associated Carcinogen `NNK´ Induced Carcinogenesis: A System Biology Approach. PMID:31357510
Host Genetics, Innate Immune Responses, and Cellular Death Pathways in Poliomyelitis Patients. PMID:31354645
Key inflammatory pathway activations in the MCI stage of Alzheimer's disease. PMID:31353852
Identification of Biomarkers Related to Neuropathic Pain Induced by Peripheral Nerve Injury. PMID:31352588
A Review of Bioinformatics Tools to Understand Acetaminophen-Alcohol Interaction. PMID:31349598
Integrated identification of key genes and pathways in Alzheimer's disease via comprehensive bioinformatical analyses. PMID:31346329
In silico analysis excavates potential biomarkers by constructing miRNA-mRNA networks between non-cirrhotic HCC and cirrhotic HCC. PMID:31346321
Integrated analyses of microRNA-29 family and the related combination biomarkers demonstrate their widespread influence on risk, recurrence, metastasis and survival outcome in colorectal cancer. PMID:31346316
Evolutionary and Comparative Expression Analyses of TCP Transcription Factor Gene Family in Land Plants. PMID:31340456
The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling. PMID:31339449
Network analysis of hyphae forming proteins in Candida albicans identifies important proteins responsible for pathovirulence in the organism. PMID:31338453
Flower bud proteome reveals modulation of sex-biased proteins potentially associated with sex expression and modification in dioecious Coccinia grandis. PMID:31337343
In Silico Analysis of Gene Expression Change Associated with Copy Number of Enhancers in Pancreatic Adenocarcinoma. PMID:31336658
Using deep maxout neural networks to improve the accuracy of function prediction from protein interaction networks. PMID:31335894
oqxAB-Positive IncHI2 Plasmid pHXY0908 Increase Salmonella enterica Serotype Typhimurium Strains Tolerance to Ciprofloxacin. PMID:31334135
Co-Expression Network Analysis Identified Gene Signatures in Osteosarcoma as a Predictive Tool for Lung Metastasis and Survival. PMID:31333788
Interferon-Inducible Protein 16 (IFI16) Has a Broad-Spectrum Binding Ability Against ssDNA Targets: An Evolutionary Hypothesis for Antiretroviral Checkpoint. PMID:31333597
Interaction Network Prediction and Analysis of Anorexia Nervosa. PMID:31327968
Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells. PMID:31324758
Genome-wide investigation of the clinical significance and prospective molecular mechanism of minichromosome maintenance protein family genes in patients with Lung Adenocarcinoma. PMID:31323040
Diagnostic and prognostic values of integrin α subfamily mRNA expression in colon adenocarcinoma. PMID:31322253
Diagnostic and prognostic value of WNT family gene expression in hepatitis B virus‑related hepatocellular carcinoma. PMID:31322232
Proteo-metabolomic investigation of transgenic rice unravels metabolic alterations and accumulation of novel proteins potentially involved in defence against Rhizoctonia solani. PMID:31320685
MiR-222-3p in Platelets Serves as a Distinguishing Marker for Early Recognition of Kawasaki Disease. PMID:31316949
Integrated bioinformatics analysis reveals novel hub genes closely associated with pathological mechanisms of immunoglobulin A nephropathy. PMID:31316619
Analysis of the equine "cumulome" reveals major metabolic aberrations after maturation in vitro. PMID:31315563
Analysis of networks of host proteins in the early time points following HIV transduction. PMID:31315557
The first evidence of global meat phosphoproteome changes in response to pre-slaughter stress. PMID:31315554
Functional DNA variations associated with Saudi female with low VO2max: a pilot microarray study. PMID:31312377
Membrane protein-regulated networks across human cancers. PMID:31311925
[Identification of differentially expressed genes in peripheral blood mononuclear cells of patients with hepatocellular carcinoma and its regulatory network analysis]. PMID:31309752
EPIC: software toolkit for elution profile-based inference of protein complexes. PMID:31308550
The transcriptome of potato tuber phellogen reveals cellular functions of cork cambium and genes involved in periderm formation and maturation. PMID:31308437
NGSEA: Network-Based Gene Set Enrichment Analysis for Interpreting Gene Expression Phenotypes with Functional Gene Sets. PMID:31307154
CDKN2B upregulation prevents teratoma formation in multipotent fibromodulin-reprogrammed cells. PMID:31305260
Bioinformatics analysis of molecular genetic targets and key pathways for hepatocellular carcinoma. PMID:31303768
Dependency Between Protein-Protein Interactions and Protein Variability and Evolutionary Rates in Vertebrates: Observed Relationships and Stochastic Modeling. PMID:31302723
Is there a Function for a Sex Pheromone Precursor? PMID:31301673
Translational regulation contributes to the secretory response of chondrocytic cells following exposure to interleukin-1β. PMID:31300557
Data from differentially expressed proteins in platelet components associated with adverse transfusion reactions. PMID:31297409
Comprehensive in vivo identification of the c-Myc mRNA protein interactome using HyPR-MS. PMID:31296583
Caenorhabditis elegans hub genes that respond to amyloid beta are homologs of genes involved in human Alzheimer's disease. PMID:31291334
Integrated analysis of competing endogenous RNA network revealing potential prognostic biomarkers of hepatocellular carcinoma. PMID:31289599
Investigation of differentially expressed genes in nasopharyngeal carcinoma by integrated bioinformatics analysis. PMID:31289570
Bioinformatics prediction and analysis of hub genes and pathways of three types of gynecological cancer. PMID:31289534
Genetic interactions of G-quadruplexes in humans. PMID:31287417
Proteomic study of the membrane components of signalling cascades of Botrytis cinerea controlled by phosphorylation. PMID:31285484
Genome-scale metabolic model of the rat liver predicts effects of diet restriction. PMID:31285465
BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas. PMID:31285370
Association of childhood traumatization and neuropsychiatric outcomes with altered plasma micro RNA-levels. PMID:31284290
Identification of RBPMS as a mammalian smooth muscle master splicing regulator via proximity of its gene with super-enhancers. PMID:31283468
Genome-wide functional association networks: background, data & state-of-the-art resources. PMID:31281921
Delineating the Plausible Molecular Vaccine Candidates and Drug Targets of Multidrug-Resistant Acinetobacter baumannii. PMID:31281799
Identification of Potential Biomarkers with Diagnostic Value in Pituitary Adenomas Using Prediction Analysis for Microarrays Method. PMID:31280474
Application of Proteomics Profiling for Biomarker Discovery in Hypertrophic Cardiomyopathy. PMID:31278493
A Novel Genes Signature Associated with the Progression of Polycystic Ovary Syndrome. PMID:31278444
High Constitutive Cytokine Release by Primary Human Acute Myeloid Leukemia Cells Is Associated with a Specific Intercellular Communication Phenotype. PMID:31277464
Identification of crucial miRNAs and genes in esophageal squamous cell carcinoma by miRNA-mRNA integrated analysis. PMID:31277149
Cancer driver genes: a guilty by resemblance doctrine. PMID:31275738
Mechanisms of Compound Kushen Injection for the Treatment of Lung Cancer Based on Network Pharmacology. PMID:31275410
Chemoproteomic Method for Profiling Inhibitor-Bound Kinase Complexes. PMID:31274292
Utilising network pharmacology to explore the underlying mechanism of Wumei Pill in treating pancreatic neoplasms. PMID:31272505
Genome-wide identification and functional analysis of oleosin genes in Brassica napus L. PMID:31272381
Integrating proteomics and transcriptomics for the identification of potential targets in early colorectal cancer. PMID:31268166
A systems biology pipeline identifies regulatory networks for stem cell engineering. PMID:31267104
Listeria monocytogenes Biofilm Adaptation to Different Temperatures Seen Through Shotgun Proteomics. PMID:31259174
CREB deletion increases resilience to stress and downregulates inflammatory gene expression in the hippocampus. PMID:31255680
A genetics-led approach defines the drug target landscape of 30 immune-related traits. PMID:31253980
Varroa destructor parasitism has a greater effect on proteome changes than the deformed wing virus and activates TGF-β signaling pathways. PMID:31253851
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking. PMID:31253831
Improving the diagnostic yield of exome- sequencing by predicting gene-phenotype associations using large-scale gene expression analysis. PMID:31253775
DYNC1I1 Promotes the Proliferation and Migration of Gastric Cancer by Up-Regulating IL-6 Expression. PMID:31249807
Differential genetic and functional background in inflammatory bowel disease phenotypes of a Greek population: a systems bioinformatics approach. PMID:31249629
Comparative Proteomic Analysis of Proteins Involved in Bioenergetics Pathways Associated with Human Sperm Motility. PMID:31248186
A tropomyosin receptor kinase family protein, NTRK2 is a potential predictive biomarker for lung adenocarcinoma. PMID:31245181
Comparative Analysis of Gene Expression in Virulent and Attenuated Strains of Infectious Bronchitis Virus at Subcodon Resolution. PMID:31243124
A Role for the VPS Retromer in Brucella Intracellular Replication Revealed by Genomewide siRNA Screening. PMID:31243080
Enteropathogenic Escherichia coli remodels host endosomes to promote endocytic turnover and breakdown of surface polarity. PMID:31242273
Long non-coding RNA FLJ33360 participates in ovarian cancer progression by sponging miR-30b-3p. PMID:31239715
Integration of CLIP experiments of RNA-binding proteins: a novel approach to predict context-dependent splicing factors from transcriptomic data. PMID:31238884
Deep transcriptome analysis using RNA-Seq suggests novel insights into molecular aspects of fat-tail metabolism in sheep. PMID:31235755
Histone H2B monoubiquitination regulates heart development via epigenetic control of cilia motility. PMID:31235600
Mutual editing of alternative splicing between breast cancer cells and macrophages. PMID:31233192
MepmiRDB: a medicinal plant microRNA database. PMID:31231773
Comparative analysis of the transcriptomes of the calyx abscission zone of sweet orange insights into the huanglongbing-associated fruit abscission. PMID:31231529
Mass Spectrometry-Based Proteomics Approach Characterizes the Dual Functionality of miR-328 in Monocytes. PMID:31231226
Biological conversion of methane to putrescine using genome-scale model-guided metabolic engineering of a methanotrophic bacterium Methylomicrobium alcaliphilum 20Z. PMID:31223337
RST1 Is a FREE1 Suppressor That Negatively Regulates Vacuolar Trafficking in Arabidopsis. PMID:31221737
Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus. PMID:31221621
Anti-obesity effects of Spirulina platensis protein hydrolysate by modulating brain-liver axis in high-fat diet fed mice. PMID:31220177
A large-scale CRISPR screen and identification of essential genes in cellular senescence bypass. PMID:31219803
Global transcriptomic analysis identifies SERPINE1 as a prognostic biomarker associated with epithelial-to-mesenchymal transition in gastric cancer. PMID:31218131
Computational identification of protein-protein interactions in model plant proteomes. PMID:31217453
Circulating tumor cell and cell-free RNA capture and expression analysis identify platelet-associated genes in metastatic lung cancer. PMID:31215484
Analysis of Genes Involved in Ulcerative Colitis Activity and Tumorigenesis Through Systematic Mining of Gene Co-expression Networks. PMID:31214045
Prediction of VEGF-C as a Key Target of Pure Total Flavonoids From Citrus Against NAFLD in Mice via Network Pharmacology. PMID:31214028
Expressions of HLA Class II Genes in Cutaneous Melanoma Were Associated with Clinical Outcome: Bioinformatics Approaches and Systematic Analysis of Public Microarray and RNA-Seq Datasets. PMID:31212865
Degradome of soluble ADAM10 and ADAM17 metalloproteases. PMID:31209506
Novel interconnections of HOG signaling revealed by combined use of two proteomic software packages. PMID:31208443
Quantitative Trait Locus and Integrative Genomics Revealed Candidate Modifier Genes for Ectopic Mineralization in Mouse Models of Pseudoxanthoma Elasticum. PMID:31207231
Investigation of new candidate genes in retinoblastoma using the TruSight One "clinical exome" gene panel. PMID:31207142
An expanded proteome of cardiac t-tubules. PMID:31202980
The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation. PMID:31200561
Decrypting protein surfaces by combining evolution, geometry, and molecular docking. PMID:31199528
CoCoScore: context-aware co-occurrence scoring for text mining applications using distant supervision. PMID:31199464
Construction and analysis of an interologous protein-protein interaction network of Camellia sinensis leaf (TeaLIPIN) from RNA-Seq data sets. PMID:31197449
MicroRNA-guided regulation of heat stress response in wheat. PMID:31195958
Identification of a 5-Gene Signature Predicting Progression and Prognosis of Clear Cell Renal Cell Carcinoma. PMID:31194719
Upregulation of the APE1 and H2AX genes and miRNAs involved in DNA damage response and repair in gastric cancer. PMID:31194025
Integrated Bioinformatic Analysis of a Competing Endogenous RNA Network Reveals a Prognostic Signature in Endometrial Cancer. PMID:31192139
Gene screening of colorectal cancers via network analysis. PMID:31191840
ANXA2, PRKCE, and OXT are critical differentially genes in Nonalcoholic fatty liver disease. PMID:31191837
Three Capsular Polysaccharide Synthesis-Related Glucosyltransferases, GT-1, GT-2 and WcaJ, Are Associated With Virulence and Phage Sensitivity of Klebsiella pneumoniae. PMID:31191500
Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer. PMID:31189116
A multidimensional perspective on microbial interactions. PMID:31187139
A catalog of single nucleotide changes distinguishing modern humans from archaic hominins. PMID:31186485
Fast optimization of non-negative matrix tri-factorization. PMID:31185054
Bioinformatics Analysis of Gene Expression Profiles of Sex Differences in Ischemic Stroke. PMID:31183363
Detection of novel biomarkers for early detection of Non-Muscle-Invasive Bladder Cancer using Competing Endogenous RNA network analysis. PMID:31182759
Evaluation of the diagnostic ability of laminin gene family for pancreatic ductal adenocarcinoma. PMID:31182680
Transcriptome analysis of responses to bluetongue virus infection in Aedes albopictus cells. PMID:31182015
Genetic resistance to DEHP-induced transgenerational endocrine disruption. PMID:31181066
Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway. PMID:31180559
Pharmacogenetic Factors Affecting Asthma Treatment Response. Potential Implications for Drug Therapy. PMID:31178722
Nerve Growth Factor Induces Proliferation and Aggressiveness In Prostate Cancer Cells. PMID:31174415
A Fast and Flexible Framework for Network-Assisted Genomic Association. PMID:31174177
Comprehensive Analysis Reveals a 4-Gene Signature in Predicting Response to Temozolomide in Low-Grade Glioma Patients. PMID:31167546
Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles. PMID:31167148
Genome-wide survey and expression analyses of the GRAS gene family in Brassica napus reveals their roles in root development and stress response. PMID:31161396
m6A Regulates Neurogenesis and Neuronal Development by Modulating Histone Methyltransferase Ezh2. PMID:31154015
Extracellular DNA release, quorum sensing, and PrrF1/F2 small RNAs are key players in Pseudomonas aeruginosa tobramycin-enhanced biofilm formation. PMID:31149345
Plasmodium pseudo-Tyrosine Kinase-like binds PP1 and SERA5 and is exported to host erythrocytes. PMID:31148576
Novel secretome-to-transcriptome integrated or secreto-transcriptomic approach to reveal liquid biopsy biomarkers for predicting individualized prognosis of breast cancer patients. PMID:31146747
Predicting pathogenicity of missense variants with weakly supervised regression. PMID:31144781
Correlation between pri-miR-124 (rs531564) polymorphism and congenital heart disease susceptibility in Chinese population at two different altitudes: a case-control and in silico study. PMID:31144180
c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma. PMID:31142587
Nanoparticle exposure driven circulating bioactive peptidome causes systemic inflammation and vascular dysfunction. PMID:31142334
Network Analyses of Differentially Expressed Genes in Osteoarthritis to Identify Hub Genes. PMID:31139654
Novel Prognostic Markers in Triple-Negative Breast Cancer Discovered by MALDI-Mass Spectrometry Imaging. PMID:31139569
Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains. PMID:31138642
NECTIN4 (PVRL4) as Putative Therapeutic Target for a Specific Subtype of High Grade Serous Ovarian Cancer-An Integrative Multi-Omics Approach. PMID:31137558
Gene Expression Studies to Identify Significant Genes in AR, MTOR, MAPK Pathways and their Overlapping Regulatory Role in Prostate Cancer. PMID:31136301
Proteomics Profiling of Host Cell Response via Protein Expression and Phosphorylation upon Dengue Virus Infection. PMID:31134586
Identification of a Combined RNA Prognostic Signature in Adenocarcinoma of the Lung. PMID:31132294
Personalized medicine-concepts, technologies, and applications in inflammatory skin diseases. PMID:31124204
Proteomic Analysis of MeJa-Induced Defense Responses in Rice against Wounding. PMID:31121967
Proteomic Analysis of the Breast Cancer Brain Metastasis Microenvironment. PMID:31121957
Discovering Biomarkers and Pathways Shared by Alzheimer's Disease and Ischemic Stroke to Identify Novel Therapeutic Targets. PMID:31121943
Investigation of the clinical significance and prospective molecular mechanisms of cystatin genes in patients with hepatitis B virus‑related hepatocellular carcinoma. PMID:31115549
Integrated bioinformatic analysis of differentially expressed genes and signaling pathways in plaque psoriasis. PMID:31115544
BEERE: a web server for biomedical entity expansion, ranking and explorations. PMID:31114876
Systems Biology Understanding of the Effects of Lithium on Cancer. PMID:31114752
Transcriptional profiling of coaggregation interactions between Streptococcus gordonii and Veillonella parvula by Dual RNA-Seq. PMID:31113978
Specific Binding Peptides from Rv3632: A Strategy for Blocking Mycobacterium tuberculosis Entry to Target Cells? PMID:31111070
NetGO: improving large-scale protein function prediction with massive network information. PMID:31106361
Overexpression of ASPM, CDC20, and TTK Confer a Poorer Prognosis in Breast Cancer Identified by Gene Co-expression Network Analysis. PMID:31106147
Identification of potential therapeutic target genes in mouse mesangial cells associated with diabetic nephropathy using bioinformatics analysis. PMID:31105790
LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML. PMID:31105032
Early Cancer Detection from Multianalyte Blood Test Results. PMID:31103852
Analysis of the Human Kinome and Phosphatome by Mass Cytometry Reveals Overexpression-Induced Effects on Cancer-Related Signaling. PMID:31101498
Identification of Potential Transcriptional Biomarkers Differently Expressed in Both S. aureus- and E. coli-Induced Sepsis via Integrated Analysis. PMID:31093495
In silico prediction of housekeeping long intergenic non-coding RNAs reveals HKlincR1 as an essential player in lung cancer cell survival. PMID:31089191
Human PRPF40B regulates hundreds of alternative splicing targets and represses a hypoxia expression signature. PMID:31088860
miRNA deregulation targets specific pathways in leiomyosarcoma development: an in silico analysis. PMID:31088504
Another look at matrix correlations. PMID:31081021
GPCRomics: An Approach to Discover GPCR Drug Targets. PMID:31078319
Exact hypothesis testing for shrinkage-based Gaussian graphical models. PMID:31077287
Tissue-specific genes as an underutilized resource in drug discovery. PMID:31076736
Bioinformatic Analysis of Gene Variants from Gastroschisis Recurrence Identifies Multiple Novel Pathogenetic Pathways: Implication for the Closure of the Ventral Body Wall. PMID:31075877
GScluster: network-weighted gene-set clustering analysis. PMID:31072324
Aberrant gene expression by Sertoli cells in infertile men with Sertoli cell-only syndrome. PMID:31071133
Return to the Sea, Get Huge, Beat Cancer: An Analysis of Cetacean Genomes Including an Assembly for the Humpback Whale (Megaptera novaeangliae). PMID:31070747
Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis. PMID:31070582
Gene pathogenicity prediction of Mendelian diseases via the random forest algorithm. PMID:31069506
Comparison of Proteome Composition of Serum Enriched in Extracellular Vesicles Isolated from Polycythemia Vera Patients and Healthy Controls. PMID:31064135
RNA-sequencing data highlighting the time-of-day-dependent transcriptome of the central circadian pacemaker in Sox2-deficient mice. PMID:31061857
A TMEFF2-regulated cell cycle derived gene signature is prognostic of recurrence risk in prostate cancer. PMID:31060542
What Changed on the Folliculogenesis in the Process of Mouse Ovarian Aging? PMID:31058188
Microfluidic reactors for advancing the MS analysis of fast biological responses. PMID:31057934
Classification and Interactions of LRR Receptors and Co-receptors Within the Arabidopsis Plasma Membrane - An Overview. PMID:31057579
Molecular Origins of Complex Heritability in Natural Genotype-to-Phenotype Relationships. PMID:31054809
Drug Combinations: Mathematical Modeling and Networking Methods. PMID:31052580
Proteome data of female Anopheles stephensi antennae. PMID:31049374
Analysis of potential key genes in very early hepatocellular carcinoma. PMID:31043166
Protein expression profiling of plasma and lungs at different stages of metastatic development in a human triple negative breast cancer xenograft model. PMID:31042781
Systems biology in inflammatory bowel diseases: on the way to precision medicine. PMID:31040620
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. PMID:31040226
Rescue of premature aging defects in Cockayne syndrome stem cells by CRISPR/Cas9-mediated gene correction. PMID:31037510
Protein Interaction Mapping related to Becker Muscular Dystrophy. PMID:31037085
Marek's Disease Virus Regulates the Ubiquitylome of Chicken CD4+ T Cells to Promote Tumorigenesis. PMID:31035338
Multigenic truncation of the semaphorin-plexin pathway by a germline chromothriptic rearrangement associated with Moebius syndrome. PMID:31033088
Epigenetic Field Cancerization in Gastric Cancer: microRNAs as Promising Biomarkers. PMID:31031866
Disentangling Genetic and Environmental Effects on the Proteotypes of Individuals. PMID:31031010
RIPK1 suppresses apoptosis mediated by TNF and caspase-3 in intervertebral discs. PMID:31029152
Macrophages Infected by a Pathogen and a Non-pathogen Spotted Fever Group Rickettsia Reveal Differential Reprogramming Signatures Early in Infection. PMID:31024862
A Convergent Study of Genetic Variants Associated With Crohn's Disease: Evidence From GWAS, Gene Expression, Methylation, eQTL and TWAS. PMID:31024628
Manganese-induced cellular disturbance in the baker's yeast, Saccharomyces cerevisiae with putative implications in neuronal dysfunction. PMID:31024033
TASmania: A bacterial Toxin-Antitoxin Systems database. PMID:31022176
Effect of CO2 Concentration on Uptake and Assimilation of Inorganic Carbon in the Extreme Acidophile Acidithiobacillus ferrooxidans. PMID:31019493
An Intramolecular Salt Bridge Linking TDP43 RNA Binding, Protein Stability, and TDP43-Dependent Neurodegeneration. PMID:31018129
PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination. PMID:31018126
In silico learning of tumor evolution through mutational time series. PMID:31015295
The Pathway to Cancer Cachexia: MicroRNA-Regulated Networks in Muscle Wasting Based on Integrative Meta-Analysis. PMID:31013615
The Effects of Epigallocatechin Gallate (EGCG) on Pulmonary Fibroblasts of Idiopathic Pulmonary Fibrosis (IPF)-A Next-Generation Sequencing and Bioinformatic Approach. PMID:31013581
Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression. PMID:31010829
Identification of DNA methylation patterns predisposing for an efficient response to BCG vaccination in healthy BCG-naïve subjects. PMID:31010371
Prolactin Receptor Signaling Regulates a Pregnancy-Specific Transcriptional Program in Mouse Islets. PMID:31004482
Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes. PMID:31004051
Altered Expression and Localization of Tumor Suppressive E3 Ubiquitin Ligase SMURF2 in Human Prostate and Breast Cancer. PMID:31003445
Upregulation of MicroRNA-21 promotes tumorigenesis of prostate cancer cells by targeting KLF5. PMID:31002531
Transcriptome Analysis Revealed a Highly Connected Gene Module Associated With Cirrhosis to Hepatocellular Carcinoma Development. PMID:31001331
Conserved MicroRNA Act Boldly During Sprout Development and Quality Formation in Pingyang Tezaocha (Camellia sinensis). PMID:31001312
UCP1 expression-associated gene signatures of human epicardial adipose tissue. PMID:30996144
Phosphoproteome Analysis of Cells Infected with Adapted and Nonadapted Influenza A Virus Reveals Novel Pro- and Antiviral Signaling Networks. PMID:30996098
The Influenza A Virus Endoribonuclease PA-X Usurps Host mRNA Processing Machinery to Limit Host Gene Expression. PMID:30995476
Interplay of cold shock protein E with an uncharacterized protein, YciF, lowers porin expression and enhances bile resistance in Salmonella Typhimurium. PMID:30992363
A photocleavable surfactant for top-down proteomics. PMID:30988469
Structural Genome Variations Related to Craniosynostosis. PMID:30976277
Comparative RNA sequencing reveals that HPV16 E6 abrogates the effect of E6*I on ROS metabolism. PMID:30976051
Sensitive Quantitative Proteomics of Human Hematopoietic Stem and Progenitor Cells by Data-independent Acquisition Mass Spectrometry. PMID:30975897
Construction of Potential Glioblastoma Multiforme-Related miRNA-mRNA Regulatory Network. PMID:30971889
Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain. PMID:30971208
Comparative analysis of homologous aminopeptidase PepN from pathogenic and non-pathogenic mycobacteria reveals divergent traits. PMID:30969995
Genes Whose Gain or Loss-of-Function Increases Endurance Performance in Mice: A Systematic Literature Review. PMID:30967789
The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP). PMID:30967474
A plasma protein derived TGFβ signature is a prognostic indicator in triple negative breast cancer. PMID:30963111
The auxin response factor gene family in allopolyploid Brassica napus. PMID:30958842
Comprehensive analysis of differentially expressed profiles and reconstruction of a competing endogenous RNA network in papillary renal cell carcinoma. PMID:30957192
Music-performance regulates microRNAs in professional musicians. PMID:30956902
O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes. PMID:30952976
IFITM3 knockdown reduces the expression of CCND1 and CDK4 and suppresses the growth of oral squamous cell carcinoma cells. PMID:30949979
Preeclampsia-Associated Alteration of DNA Methylation in Fetal Endothelial Progenitor Cells. PMID:30949477
Irradiation-induced dynamic changes of gene signatures reveal gain of metastatic ability in nasopharyngeal carcinoma. PMID:30949405
Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites. PMID:30943267
Genotype-phenotype relations of the von Hippel-Lindau tumor suppressor inferred from a large-scale analysis of disease mutations and interactors. PMID:30943211
A Multi-Cohort and Multi-Omics Meta-Analysis Framework to Identify Network-Based Gene Signatures. PMID:30941158
The mechanical effects of CRT promoting autophagy via mitochondrial calcium uniporter down-regulation and mitochondrial dynamics alteration. PMID:30938090
In silico identification of key genes and signaling pathways targeted by a panel of signature microRNAs in prostate cancer. PMID:30937635
A Network Module for the Perseus Software for Computational Proteomics Facilitates Proteome Interaction Graph Analysis. PMID:30931570
A Ubiquitous Platform for Bacterial Nanotube Biogenesis. PMID:30929979
Liver proteomics unravel the metabolic pathways related to Feed Efficiency in beef cattle. PMID:30926873
Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry. PMID:30924900
Integrated bioinformatics analysis of As, Au, Cd, Pb and Cu heavy metal responsive marker genes through Arabidopsis thaliana GEO datasets. PMID:30918749
Protein-protein interactions of the nicotinamide/nicotinate mononucleotide adenylyltransferase of Leishmania braziliensis. PMID:30916117
SUMOylation promotes protective responses to DNA-protein crosslinks. PMID:30914427
Encircling the regions of the pharmacogenomic landscape that determine drug response. PMID:30914058
Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. PMID:30912746
Long non-coding RNA SNHG6 is upregulated in prostate cancer and predicts poor prognosis. PMID:30911973
New Insight on Solute Carrier Family 27 Member 6 (SLC27A6) in Tumoral and Non-Tumoral Breast Cells. PMID:30911270
Genome-wide association study of blood lipids in Indians confirms universality of established variants. PMID:30911093
A Genome-Wide Analysis of the Penumbral Volume in Inbred Mice following Middle Cerebral Artery Occlusion. PMID:30911049
Molecular Players of EF-hand Containing Calcium Signaling Event in Plants. PMID:30909616
Integrated transcriptome interactome study of oncogenes and tumor suppressor genes in breast cancer. PMID:30906836
Computational Molecular Phenotypic Analysis of PTPN22 (W620R), IL6R (D358A), and TYK2 (P1104A) Gene Mutations of Rheumatoid Arthritis. PMID:30899276
Genome-scale integrated analysis to identify prospective molecular mechanisms and therapeutic targets in isocitrate dehydrogenase 2 R140Q-mutated acute myeloid leukemia. PMID:30896832
Diagnostic and prognostic value of mRNA expression of phospholipase C β family genes in hepatitis B virus‑associated hepatocellular carcinoma. PMID:30896816
Identification of EGFR as a Novel Key Gene in Clear Cell Renal Cell Carcinoma (ccRCC) through Bioinformatics Analysis and Meta-Analysis. PMID:30895194
A Pathogen and a Non-pathogen Spotted Fever Group Rickettsia Trigger Differential Proteome Signatures in Macrophages. PMID:30895174
Transcriptome analysis of rumen epithelium and meta-transcriptome analysis of rumen epimural microbial community in young calves with feed induced acidosis. PMID:30894588
Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo. PMID:30893613
The Selection of a Hepatocyte Cell Line Susceptible to Plasmodium falciparum Sporozoite Invasion That Is Associated With Expression of Glypican-3. PMID:30891005
Transcriptome Analysis of the Human Tibial Nerve Identifies Sexually Dimorphic Expression of Genes Involved in Pain, Inflammation, and Neuro-Immunity. PMID:30890918
Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing. PMID:30890647
Quantitative Proteomics Links the Intermediate Filament Nestin to Resistance to Targeted BRAF Inhibition in Melanoma Cells. PMID:30890564
Gene Expression Networks Across Multiple Tissues Are Associated with Rates of Molecular Evolution in Wild House Mice. PMID:30889893
γ-proteobacteria eject their polar flagella under nutrient depletion, retaining flagellar motor relic structures. PMID:30889173
Proteomic profiling of the mouse diaphragm and refined mass spectrometric analysis of the dystrophic phenotype. PMID:30888583
Candidate genes involved in metastasis of colon cancer identified by integrated analysis. PMID:30884206
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells toward Treg-mediated suppression of cytokine expression. PMID:30882958
The chaperone ERp29 is required for tunneling nanotube formation by stabilizing MSec. PMID:30877198
Infrastructures of systems biology that facilitate functional genomic study in rice. PMID:30874968
Sulforaphane metabolites inhibit migration and invasion via microtubule-mediated Claudins dysfunction or inhibition of autolysosome formation in human non-small cell lung cancer cells. PMID:30874545
How Does Fusarium oxysporum Sense and Respond to Nicotinaldehyde, an Inhibitor of the NAD+ Salvage Biosynthesis Pathway? PMID:30873138
Identification and analysis of genes associated with papillary thyroid carcinoma by bioinformatics methods. PMID:30872410
Arsenic Trioxide and (-)-Gossypol Synergistically Target Glioma Stem-Like Cells via Inhibition of Hedgehog and Notch Signaling. PMID:30871073
Mutations in gliclazide-associated genes may predict poor bladder cancer prognosis. PMID:30868054
Quantitative proteomic changes in LPS-activated monocyte-derived dendritic cells: A SWATH-MS study. PMID:30867486
A systematic review and standardized clinical validity assessment of male infertility genes. PMID:30865283
The Protein-Protein Interaction Network of Litopenaeus vannamei Haemocytes. PMID:30863321
Developmental Dieldrin Exposure Alters DNA Methylation at Genes Related to Dopaminergic Neuron Development and Parkinson's Disease in Mouse Midbrain. PMID:30859219
Prognostic and Clinicopathological Significance of SERTAD1 in Various Types of Cancer Risk: A Systematic Review and Retrospective Analysis. PMID:30857225
Increased expression of plakophilin 3 is associated with poor prognosis in ovarian cancer. PMID:30855445
Chromatin capture links the metabolic enzyme AHCY to stem cell proliferation. PMID:30854431
Genome-wide analysis of yeast expression data based on a priori generated co-regulation cliques. PMID:30854393
PIMKL: Pathway-Induced Multiple Kernel Learning. PMID:30854223
Knockdown of high mobility group box 3 impairs cell viability and colony formation but increases apoptosis in A549 human non-small cell lung cancer cells. PMID:30854071
Comprehensive Analysis of Driver Genes in Personal Genomes of Clear Cell Renal Cell Carcinoma. PMID:30852945
Design, implementation, and operation of a rapid, robust named entity recognition web service. PMID:30850898
Connectivity mapping of angiotensin-PPAR interactions involved in the amelioration of non-alcoholic steatohepatitis by Telmisartan. PMID:30850637
Drug repositioning in epilepsy reveals novel antiseizure candidates. PMID:30847362
Gene Expression Changes Associated with Nintedanib Treatment in Idiopathic Pulmonary Fibrosis Fibroblasts: A Next-Generation Sequencing and Bioinformatics Study. PMID:30841487
Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. PMID:30838976
Integrative Analysis Reveals Key Circular RNA in Atrial Fibrillation. PMID:30838031
Comparative Gene Expression Profiles in Parathyroid Adenoma and Normal Parathyroid Tissue. PMID:30832348
Compendium of synovial signatures identifies pathologic characteristics for predicting treatment response in rheumatoid arthritis patients. PMID:30831253
Proteomic Identification of Protein Glutathionylation in Cardiomyocytes. PMID:30831029
B lymphocyte alterations accompany abatacept resistance in new-onset type 1 diabetes. PMID:30830871
Biclustering analysis of transcriptome big data identifies condition-specific microRNA targets. PMID:30820547
In silico analysis identified miRNA‑based therapeutic agents against glioblastoma multiforme. PMID:30816530
The underlying molecular mechanism and potential drugs for treatment in papillary renal cell carcinoma: A study based on TCGA and Cmap datasets. PMID:30816528
The analysis of a time-course transcriptome profile by systems biology approaches reveals key molecular processes in acute kidney injury. PMID:30815016
The evolution of gene regulatory networks controlling Arabidopsis thaliana L. trichome development. PMID:30813891
mtProtEvol: the resource presenting molecular evolution analysis of proteins involved in the function of Vertebrate mitochondria. PMID:30813887
Prediction of Drug Positioning for Quan-Du-Zhong Capsules Against Hypertensive Nephropathy Based on the Robustness of Disease Network. PMID:30809144
Origin and evolution of the octoploid strawberry genome. PMID:30804557
Blubber transcriptome responses to repeated ACTH administration in a marine mammal. PMID:30804370
System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection. PMID:30799147
An Advanced Strategy for Comprehensive Profiling of ADP-ribosylation Sites Using Mass Spectrometry-based Proteomics. PMID:30798302
Multi-omics identify xanthine as a pro-survival metabolite for nematodes with mitochondrial dysfunction. PMID:30796049
Testosterone Administration after Traumatic Brain Injury Reduces Mitochondrial Dysfunction and Neurodegeneration. PMID:30794079
A Network Pharmacology Approach to Explore Mechanism of Action of Longzuan Tongbi Formula on Rheumatoid Arthritis. PMID:30792744
Extracellular vesicles derived from cancer-associated fibroblasts induce the migration and invasion of oral squamous cell carcinoma. PMID:30788085
Cold Tolerance Regulated by the Pyruvate Metabolism in Vibrio parahaemolyticus. PMID:30787922
Comparative Genomic Analyses Reveal Core-Genome-Wide Genes Under Positive Selection and Major Regulatory Hubs in Outlier Strains of Pseudomonas aeruginosa. PMID:30787911
Identification and Expression Analysis of Long Noncoding RNAs in Fat-Tail of Sheep Breeds. PMID:30787031
Insight into Structural Characteristics of Protein-Substrate Interaction in Pimaricin Thioesterase. PMID:30781619
SRC and TP53 play critical role in low-grade dysplasia colorectal mucosa transformation into cancer. PMID:30774815
Barrett's esophagus network analysis revealed that arginine, alanine, aspartate, glutamate, valine, leucine and isoleucine can be biomarkers. PMID:30774814
Insulin dysregulation plays a critical role in colon inflammation: a bioinformatics approach. PMID:30774812
Integrated Bioinformatics Analysis of Hub Genes and Pathways in Anaplastic Thyroid Carcinomas. PMID:30774662
Investigating Common Pathogenic Mechanisms between Homo sapiens and Different Strains of Candida albicans for Drug Design: Systems Biology Approach via Two-Sided NGS Data Identification. PMID:30769958
Phosphoproteomic analyses of kidneys of Atlantic salmon infected with Aeromonas salmonicida. PMID:30765835
Proteome data of Anopheles stephensi salivary glands using high-resolution mass spectrometry analysis. PMID:30761337
Plasmodium palmitoylation machinery engineered in E. coli for high-throughput screening of palmitoyl acyl-transferase inhibitors. PMID:30761251
IMMAN: an R/Bioconductor package for Interolog protein network reconstruction, mapping and mining analysis. PMID:30755155
Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes. PMID:30753093
Integrated bioinformatics analysis of key genes involved in progress of colon cancer. PMID:30746900
Hypersensitive IFN Responses in Lupus Keratinocytes Reveal Key Mechanistic Determinants in Cutaneous Lupus. PMID:30745462
Genome-wide Identification, Expression Profiling and Evolutionary Analysis of Auxin Response Factor Gene Family in Potato (Solanum tuberosum Group Phureja). PMID:30742001
Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain. PMID:30735499
In silico studies on bacterial xylanase enzyme: Structural and functional insight. PMID:30733796
Plasmodium falciparum specific helicase 2 is a dual, bipolar helicase and is crucial for parasite growth. PMID:30728406
Network Pharmacology Integrated Molecular Docking Reveals the Antiosteosarcoma Mechanism of Biochanin A. PMID:30723510
Inferring pathogen-host interactions between Leptospira interrogans and Homo sapiens using network theory. PMID:30723266
The effect of physiological stretch and the valvular endothelium on mitral valve proteomes. PMID:30722697
Silencing the OCT4-PG1 pseudogene reduces OCT-4 protein levels and changes characteristics of the multidrug resistance phenotype in chronic myeloid leukemia. PMID:30721421
Integrative analysis of cancer driver genes in prostate adenocarcinoma. PMID:30720096
Comparative transcriptome analysis reveals new molecular pathways for cucumber genes related to sex determination. PMID:30719568
Serum Proteomic Study of Women With Obsessive-Compulsive Disorder, Washing Subtype. PMID:30719248
Integrative system genetic analysis reveals mRNA-lncRNA network associated with mouse spontaneous lung cancer susceptibility. PMID:30719228
Inferring Gene Regulatory Networks from a Population of Yeast Segregants. PMID:30718595
Fine mapping of the major QTL for seed coat color in Brassica rapa var. Yellow Sarson by use of NIL populations and transcriptome sequencing for identification of the candidate genes. PMID:30716096
The SCOOP12 peptide regulates defense response and root elongation in Arabidopsis thaliana. PMID:30715439
A miRNA-HERC4 pathway promotes breast tumorigenesis by inactivating tumor suppressor LATS1. PMID:30710319
Plasma Proteome Signature of Sepsis: a Functionally Connected Protein Network. PMID:30706660
A Pilot Study Using a Multistaged Integrated Analysis of Gene Expression and Methylation to Evaluate Mechanisms for Evening Fatigue in Women Who Received Chemotherapy for Breast Cancer. PMID:30701989
Identification of liver metastasis-associated genes in human colon carcinoma by mRNA profiling. PMID:30700932
Systematic analysis of NLMP suggests nuclear localization of RTK/MET kinases resemble cancer cell clearance. PMID:30700325
Prediction of Gold Nanoparticle and Microwave-Induced Hyperthermia Effects on Tumor Control via a Simulation Approach. PMID:30699996
Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets. PMID:30692607
Transcriptomics analysis of host liver and meta-transcriptome analysis of rumen epimural microbial community in young calves treated with artificial dosing of rumen content from adult donor cow. PMID:30692556
Chronic Cold Stress Alters the Skin Mucus Interactome in a Temperate Fish Model. PMID:30687126
Sexual dimorphism in brain transcriptomes of Amami spiny rats (Tokudaia osimensis): a rodent species where males lack the Y chromosome. PMID:30683046
Virulence Characteristics and an Action Mode of Antibiotic Resistance in Multidrug-Resistant Pseudomonas aeruginosa. PMID:30679735
Bioinformatics Analysis of Key Genes and Pathways for Medulloblastoma as a Therapeutic Target. PMID:30678435
Transcriptome-Wide Analysis of Human Chondrocyte Expansion on Synoviocyte Matrix. PMID:30678371
Integrative Analyses of Genes Associated with Subcutaneous Insulin Resistance. PMID:30678306
Genetic and genomic analyses of testicular hypoplasia in Nellore cattle. PMID:30677076
A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations. PMID:30670742
Meta-analysis of expression and methylation signatures indicates a stress-related epigenetic mechanism in multiple neuropsychiatric disorders. PMID:30670680
Systemic analysis of tyrosine kinase signaling reveals a common adaptive response program in a HER2-positive breast cancer. PMID:30670633
A dynamic and integrated epigenetic program at distal regions orchestrates transcriptional responses to VEGFA. PMID:30670628
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy. PMID:30664790
The autism/neuroprotection-linked ADNP/NAP regulate the excitatory glutamatergic synapse. PMID:30664622
Atypical Auditory Brainstem Response and Protein Expression Aberrations Related to ASD and Hearing Loss in the Adnp Haploinsufficient Mouse Brain. PMID:30659505
Relation of the pdxB-usg-truA-dedA Operon and the truA Gene to the Intracellular Survival of Salmonella enterica Serovar Typhimurium. PMID:30658401
Identification of key pathways and genes in endometrial cancer using bioinformatics analyses. PMID:30655845
Modelling and molecular docking studies of the cytoplasmic domain of Wsc-family, full-length Ras2p, and therapeutic antifungal compounds. PMID:30654316
Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor. PMID:30653502
Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin. PMID:30651137
Network Analyses of Integrated Differentially Expressed Genes in Papillary Thyroid Carcinoma to Identify Characteristic Genes. PMID:30646607
Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation. PMID:30644849
A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis. PMID:30643265
Transcriptome analysis reveals immune-related gene expression changes with age in giant panda (Ailuropoda melanoleuca) blood. PMID:30641486
Quantitative Proteomics Reveals the Dynamic Protein Landscape during Initiation of Human Th17 Cell Polarization. PMID:30641411
LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis. PMID:30638865
Deduction of Novel Genes Potentially Involved in Keratinocytes of Type 2 Diabetes Using Next-Generation Sequencing and Bioinformatics Approaches. PMID:30634634
Inhibitor of DNA-Binding/Differentiation Proteins and Environmental Toxicants: Genomic Impact on the Onset of Depressive Dysfunction. PMID:30634536
Using a Chemical Genetic Screen to Enhance Our Understanding of the Antimicrobial Properties of Gallium against Escherichia coli. PMID:30634525
Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling. PMID:30632963
Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer's disease mouse model. PMID:30631041
Chronobiology of limbic seizures: Potential mechanisms and prospects of chronotherapy for mesial temporal lobe epilepsy. PMID:30629979
Identification of prognostic biomarkers for patients with hepatocellular carcinoma after hepatectomy. PMID:30628708
IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling. PMID:30626937
CoExpresso: assess the quantitative behavior of protein complexes in human cells. PMID:30626316
Mutational profile of colorectal cancer lung metastases and paired primary tumors by targeted next generation sequencing: implications on clinical outcome after surgery. PMID:30622786
Cluster expansion of apolipoprotein D (ApoD) genes in teleost fishes. PMID:30621595
Efficacy of Integrating a Novel 16-Gene Biomarker Panel and Intelligence Classifiers for Differential Diagnosis of Rheumatoid Arthritis and Osteoarthritis. PMID:30621359
Protein Profiling of Arabidopsis Roots Treated With Humic Substances: Insights Into the Metabolic and Interactome Networks. PMID:30619394
Systems Biology Understanding of the Effects of Lithium on Affective and Neurodegenerative Disorders. PMID:30618562
RNA-seq analysis of hepatic gene expression of common Pekin, Muscovy, mule and hinny ducks fed ad libitum or overfed. PMID:30616512
Phagocytosis of Leptospira by leukocytes from mice with different susceptibility to leptospirosis and possible role of chemokines. PMID:30616505
Delineation of the pan-proteome of fish-pathogenic Streptococcus agalactiae strains using a label-free shotgun approach. PMID:30616502
HOPS-dependent endosomal fusion required for efficient cytosolic delivery of therapeutic peptides and small proteins. PMID:30610181
Biomarker Discovery for Immunotherapy of Pituitary Adenomas: Enhanced Robustness and Prediction Ability by Modern Computational Tools. PMID:30609812
Mitochondrial ribosomal protein PTCD3 mutations cause oxidative phosphorylation defects with Leigh syndrome. PMID:30607703
A homozygous G insertion in MPLKIP leads to TTDN1 with the hypergonadotropic hypogonadism symptom. PMID:30598092
Network spectra for drug-target identification in complex diseases: new guns against old foes. PMID:30596144
Putative Systemic Biomarkers of Biomass Smoke-Induced Chronic Obstructive Pulmonary Disease among Women in a Rural South Indian Population. PMID:30595762
Heterodimeric DNA motif synthesis and validations. PMID:30590725
Genome-wide analysis of consistently RNA edited sites in human blood reveals interactions with mRNA processing genes and suggests correlations with cell types and biological variables. PMID:30587120
Genetically Determined Levels of Circulating Cytokines and Risk of Stroke. PMID:30586705
Systematic Investigation of Scutellariae Barbatae Herba for Treating Hepatocellular Carcinoma Based on Network Pharmacology. PMID:30584453
Environmental Change-Dependent Inherited Epigenetic Response. PMID:30583460
Proteins Altered by Surgical Weight Loss Highlight Biomarkers of Insulin Resistance in the Community. PMID:30580566
Multiple transcription factors contribute to inter-chromosomal interaction in yeast. PMID:30577873
Clinically Relevant Post-Translational Modification Analyses-Maturing Workflows and Bioinformatics Tools. PMID:30577541
MicroRNA-31 Reduces the Motility of Proinflammatory T Helper 1 Lymphocytes. PMID:30574141
Fatherhood alters gene expression within the MPOA. PMID:30568805
Identification of differentially expressed miRNAs in early-stage cervical cancer with lymph node metastasis across The Cancer Genome Atlas datasets. PMID:30568508
Wound-Healing Markers Revealed by Proximity Extension Assay in Tears of Patients following Glaucoma Surgery. PMID:30567303
Transcriptomic profiles of muscle, heart, and spleen in reaction to circadian heat stress in Ethiopian highland and lowland male chicken. PMID:30565091
Identification of Candidate Genes and Regulatory Factors Underlying Intramuscular Fat Content Through Longissimus Dorsi Transcriptome Analyses in Heavy Iberian Pigs. PMID:30564273
Surface Immunoproteomics Reveals Potential Biomarkers in Alicyclobacillus acidoterrestris. PMID:30564227
Identifying mouse developmental essential genes using machine learning. PMID:30563825
MicroRNAs as Diagnostic and Prognostic Biomarkers in Ischemic Stroke-A Comprehensive Review and Bioinformatic Analysis. PMID:30563269
Defining a Characteristic Gene Expression Set Responsible for Cancer Stem Cell-Like Features in a Sub-Population of Ewing Sarcoma Cells CADO-ES1. PMID:30563222
Towards a Central Role of ISL1 in the Bladder Exstrophy⁻Epispadias Complex (BEEC): Computational Characterization of Genetic Variants and Structural Modelling. PMID:30563179
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization. PMID:30562941
Human Breast Cancer Xenograft Model Implicates Peroxisome Proliferator-activated Receptor Signaling as Driver of Cancer-induced Muscle Fatigue. PMID:30559167
Diet-Induced Dysbiosis and Genetic Background Synergize With Cystic Fibrosis Transmembrane Conductance Regulator Deficiency to Promote Cholangiopathy in Mice. PMID:30556040
Production of Protein-Complex Components Is Stoichiometric and Lacks General Feedback Regulation in Eukaryotes. PMID:30553725
The Ferredoxin-Like Protein FerR Regulates PrbP Activity in Liberibacter asiaticus. PMID:30552192
Personalized Medicine and Molecular Interaction Networks in Amyotrophic Lateral Sclerosis (ALS): Current Knowledge. PMID:30551677
Integrating molecular networks with genetic variant interpretation for precision medicine. PMID:30548534
Potential clinical value and putative biological function of miR-122-5p in hepatocellular carcinoma: A comprehensive study using microarray and RNA sequencing data. PMID:30546424
Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk. PMID:30545851
Regulatory motifs found in the small heat shock protein (sHSP) gene family in tomato. PMID:30537925
Putative contributions of the sex chromosome proteins SOX3 and SRY to neurodevelopmental disorders. PMID:30537354
Proteome modifications on tomato under extreme high light induced-stress. PMID:30534005
Mitoproteomics: Tackling Mitochondrial Dysfunction in Human Disease. PMID:30533169
Identification of novel candidate genes involved in the progression of emphysema by bioinformatic methods. PMID:30532529
PathFX provides mechanistic insights into drug efficacy and safety for regulatory review and therapeutic development. PMID:30532240
A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight? PMID:30522862
Downstream components of the calmodulin signaling pathway in the rice salt stress response revealed by transcriptome profiling and target identification. PMID:30518322
The Monothiol Glutaredoxin Grx4 Regulates Iron Homeostasis and Virulence in Cryptococcus neoformans. PMID:30514787
Genome-wide discovery of epistatic loci affecting antibiotic resistance in Neisseria gonorrhoeae using evolutionary couplings. PMID:30510172
Proteome-Wide Analysis of Cysteine Reactivity during Effector-Triggered Immunity. PMID:30510037
Proteomic analysis of microbial induced redox-dependent intestinal signaling. PMID:30508697
A Genome-wide Association Study Identifying RAP1A as a Novel Susceptibility Gene for Crohn's Disease in Japanese Individuals. PMID:30500874
SeqVItA: Sequence Variant Identification and Annotation Platform for Next Generation Sequencing Data. PMID:30487811
MAB21L1 loss of function causes a syndromic neurodevelopmental disorder with distinctive cerebellar, ocular, craniofacial and genital features (COFG syndrome). PMID:30487245
Immunotherapy utilizing the combination of natural killer- and antibody dependent cellular cytotoxicity (ADCC)-mediating agents with poly (ADP-ribose) polymerase (PARP) inhibition. PMID:30486888
Integrated Proteomic and Transcriptomic Analysis of Differential Expression of Chicken Lung Tissue in Response to NDV Infection during Heat Stress. PMID:30486457
Computational Modeling and Reverse Engineering to Reveal Dominant Regulatory Interactions Controlling Osteochondral Differentiation: Potential for Regenerative Medicine. PMID:30483498
Weighted Gene Correlation Network Analysis (WGCNA) Reveals Novel Transcription Factors Associated With Bisphenol A Dose-Response. PMID:30483308
STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets. PMID:30476243
The BioGRID interaction database: 2019 update. PMID:30476227
Histology-guided high-resolution AP-SMALDI mass spectrometry imaging of wheat-Fusarium graminearum interaction at the root-shoot junction. PMID:30473724
Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS. PMID:30471916
Network Pharmacology to Unveil the Biological Basis of Health-Strengthening Herbal Medicine in Cancer Treatment. PMID:30469422
Human Prolactinoma: A View of Protein-Protein Interaction Pattern. PMID:30464775
Coordinate regulation of long non-coding RNAs and protein-coding genes in germ-free mice. PMID:30463508
ProSave: an application for restoring quantitative data to manipulated subsets of protein lists. PMID:30459825
Eco-Metabolomics and Metabolic Modeling: Making the Leap From Model Systems in the Lab to Native Populations in the Field. PMID:30459786
Quantitative metaproteomics of medieval dental calculus reveals individual oral health status. PMID:30459334
Ambiguity in logic-based models of gene regulatory networks: An integrative multi-perturbation analysis. PMID:30458000
Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins. PMID:30455320
Cytoscape StringApp: Network Analysis and Visualization of Proteomics Data. PMID:30450911
Transcriptome and Proteome of Fish-Pathogenic Streptococcus agalactiae Are Modulated by Temperature. PMID:30450092
High-Throughput Identification of the Plasma Proteomic Signature of Inflammatory Bowel Disease. PMID:30445421
Screening and clinical significance of tumor markers in head and neck squamous cell carcinoma through bioinformatics analysis. PMID:30431092
Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control. PMID:30429547
Identification of Potential Key Genes Associated with Adipogenesis through Integrated Analysis of Five Mouse Transcriptome Datasets. PMID:30424473
C/VDdb: A multi-omics expression profiling database for a knowledge-driven approach in cardiovascular disease (CVD). PMID:30419069
eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses. PMID:30418610
HumanNet v2: human gene networks for disease research. PMID:30418591
Prognostic Value of Excision Repair Cross-Complementing mRNA Expression in Gastric Cancer. PMID:30417012
Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development. PMID:30413530
Quantifying the contribution of recessive coding variation to developmental disorders. PMID:30409806
Heterotrimeric G-Protein-Dependent Proteome and Phosphoproteome in Unstimulated Arabidopsis Roots. PMID:30407730
IID 2018 update: context-specific physical protein-protein interactions in human, model organisms and domesticated species. PMID:30407591
Proteomic Profiling of Burkholderia thailandensis During Host Infection Using Bio-Orthogonal Noncanonical Amino Acid Tagging (BONCAT). PMID:30406044
Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors. PMID:30403660
The pervasive effects of recombinant Fasciola gigantica Ras-related protein Rab10 on the functions of goat peripheral blood mononuclear cells. PMID:30400957
Global Analysis of WOX Transcription Factor Gene Family in Brassica napus Reveals Their Stress- and Hormone-Responsive Patterns. PMID:30400610
Lineage-Specific Expression Divergence in Grasses Is Associated with Male Reproduction, Host-Pathogen Defense, and Domestication. PMID:30398650
Limited short-term effects on human prostate cancer xenograft growth and epidermal growth factor receptor gene expression by the ghrelin receptor antagonist [D-Lys3]-GHRP-6. PMID:30390209
Proteomic profiling of liver tissue from the mdx-4cv mouse model of Duchenne muscular dystrophy. PMID:30386187
Differential expression of immune receptors in two marine sponges upon exposure to microbial-associated molecular patterns. PMID:30382170
Zika Virus Infection of Human Mesenchymal Stem Cells Promotes Differential Expression of Proteins Linked to Several Neurological Diseases. PMID:30377986
HCN Regulates Cellular Processes through Posttranslational Modification of Proteins by S-cyanylation. PMID:30377236
Acid bone lysate activates TGFβ signalling in human oral fibroblasts. PMID:30375456
Computational discovery of dynamic cell line specific Boolean networks from multiplex time-course data. PMID:30372442
Identification of Potential Gene Interactions in Heart Failure Caused by Idiopathic Dilated Cardiomyopathy. PMID:30368515
Expression, Clinical Significance, and Functional Prediction of MNX1 in Breast Cancer. PMID:30368216
Application of Proteomics Technologies in Oil Palm Research. PMID:30367348
IL-18 and S100A12 Are Upregulated in Experimental Central Retinal Vein Occlusion. PMID:30366444
Bioinformatics analysis to identify key genes and pathways influencing synovial inflammation in osteoarthritis. PMID:30365099
Substrate Specificity Analysis of Dihydrofolate/Dihydromethanopterin Reductase Homologs in Methylotrophic α-Proteobacteria. PMID:30364315
RNA Sequencing-Based Whole-Transcriptome Analysis of Friesian Cattle Fed with Grape Pomace-Supplemented Diet. PMID:30360570
Mapping of equine mesenchymal stromal cell surface proteomes for identification of specific markers using proteomics and gene expression analysis: an in vitro cross-sectional study. PMID:30359315
Genome-wide identification and analysis of the CNGC gene family in maize. PMID:30356996
Identification and characterization of NF-Y gene family in walnut (Juglans regia L.). PMID:30352551
Identification of genes and analysis of prognostic values in nonsmoking females with non-small cell lung carcinoma by bioinformatics analyses. PMID:30349363
Gene expression profiling in a mouse model of Dravet syndrome. PMID:30347190
Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents. PMID:30346968
Genetic expression profile-based screening of genes and pathways associated with papillary thyroid carcinoma. PMID:30344727
Bioinformatics identification of crucial genes and pathways associated with hepatocellular carcinoma. PMID:30341252
Peanut Stunt Virus and Its Satellite RNA Trigger Changes in Phosphorylation in N. benthamiana Infected Plants at the Early Stage of the Infection. PMID:30340407
Combining multi-OMICs information to identify key-regulator genes for pleiotropic effect on fertility and production traits in beef cattle. PMID:30335783
Transcriptome-wide association study identifies multiple genes and pathways associated with pancreatic cancer. PMID:30334361
Resveratrol: Twenty Years of Growth, Development and Controversy. PMID:30332889
Genomic data integration systematically biases interactome mapping. PMID:30332399
Exploring Protein⁻Protein Interaction in the Study of Hormone-Dependent Cancers. PMID:30326622
Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules. PMID:30323326
Mining the potential therapeutic targets for coronary artery disease by bioinformatics analysis. PMID:30320387
Immune Gene Expression Profile in Hepatocellular Carcinoma and Surrounding Tissue Predicts Time to Tumor Recurrence. PMID:30319985
Potential Effects of MSC-Derived Exosomes in Neuroplasticity in Alzheimer's Disease. PMID:30319358
Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions. PMID:30315172
Aptamer-based proteomics of serum and plasma in acquired aplastic anemia. PMID:30312735
Proteomic profiling of yeast heterochromatin connects direct physical and genetic interactions. PMID:30310994
Biallelic mutations of CFAP251 cause sperm flagellar defects and human male infertility. PMID:30310178
A Viral Protein Restricts Drosophila RNAi Immunity by Regulating Argonaute Activity and Stability. PMID:30308158
Genome-wide expression profiling of glioblastoma using a large combined cohort. PMID:30305647
The C-terminal D/E-rich domain of MBD3 is a putative Z-DNA mimic that competes for Zα DNA-binding activity. PMID:30304469
N-dodecanoyl-homoserine lactone influences the levels of thiol and proteins related to oxidation-reduction process in Salmonella. PMID:30304064
Activity-dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11. PMID:30301801
LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent. PMID:30297806
Screening and identification of potential novel biomarker for diagnosis of complicated Plasmodium vivax malaria. PMID:30286756
A complete bioconversion cascade for dehalogenation and denitration by bacterial flavin-dependent enzymes. PMID:30282807
OligoPVP: Phenotype-driven analysis of individual genomic information to prioritize oligogenic disease variants. PMID:30279426
Protein interaction and functional data indicate MTHFD2 involvement in RNA processing and translation. PMID:30275950
Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline. PMID:30275468
Exploration of Survival Traits, Probiotic Determinants, Host Interactions, and Functional Evolution of Bifidobacterial Genomes Using Comparative Genomics. PMID:30275399
Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers. PMID:30271945
Identification of key candidate genes and small molecule drugs in cervical cancer by bioinformatics strategy. PMID:30271202
WEADE: A workflow for enrichment analysis and data exploration. PMID:30265728
Darkness in the Human Gene and Protein Function Space: Widely Modest or Absent Illumination by the Life Science Literature and the Trend for Fewer Protein Function Discoveries Since 2000. PMID:30265449
d2ome, Software for in Vivo Protein Turnover Analysis Using Heavy Water Labeling and LC-MS, Reveals Alterations of Hepatic Proteome Dynamics in a Mouse Model of NAFLD. PMID:30265007
Protein Syndesmos is a novel RNA-binding protein that regulates primary cilia formation. PMID:30260431
Association of Pioglitazone with Increased Risk of Prostate Cancer and Pancreatic Cancer: A Functional Network Study. PMID:30255424
Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets. PMID:30252678
A new tool for studying waterfowl immune and metabolic responses: Molecular level analysis using kinome profiling. PMID:30250721
Viruses.STRING: A Virus-Host Protein-Protein Interaction Database. PMID:30249048
Molecular pathology of adverse local tissue reaction caused by metal-on-metal implants defined by RNA-seq. PMID:30248488
Identifying and validating blood mRNA biomarkers for acute and chronic insufficient sleep in humans: a machine learning approach. PMID:30247731
Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice. PMID:30241514
Growth Cone Phosphoproteomics Reveals that GAP-43 Phosphorylated by JNK Is a Marker of Axon Growth and Regeneration. PMID:30240740
Role of altered proteostasis network in chronic hypobaric hypoxia induced skeletal muscle atrophy. PMID:30240405
The Grayling Genome Reveals Selection on Gene Expression Regulation after Whole-Genome Duplication. PMID:30239729
Single-cell RNA-seq reveals dynamic transcriptome profiling in human early neural differentiation. PMID:30239706
Integrated Analysis of a Competing Endogenous RNA Network Revealing a Prognostic Signature for Cervical Cancer. PMID:30237984
Computational studies on Begomoviral AC2/C2 proteins. PMID:30237675
Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas. PMID:30236127
A Comprehensive In Silico Method to Study the QSTR of the Aconitine Alkaloids for Designing Novel Drugs. PMID:30231506
Proteome analysis reveals a role of rainbow trout lymphoid organs during Yersinia ruckeri infection process. PMID:30228307
Expression of the OAS Gene Family Is Highly Modulated in Subjects Affected by Juvenile Dermatomyositis, Resembling an Immune Response to a dsRNA Virus Infection. PMID:30227596
Novel urinary exosomal biomarkers of acute T cell-mediated rejection in kidney transplant recipients: A cross-sectional study. PMID:30226858
TOP2B: The First Thirty Years. PMID:30223465
Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16. PMID:30222779
Identification of key genes and associated pathways in KIT/PDGFRA wild‑type gastrointestinal stromal tumors through bioinformatics analysis. PMID:30221743
Network analysis of membranous glomerulonephritis based on metabolomics data. PMID:30221719
Aspirin promotes apoptosis and inhibits proliferation by blocking G0/G1 into S phase in rheumatoid arthritis fibroblast-like synoviocytes via downregulation of JAK/STAT3 and NF-κB signaling pathway. PMID:30221683
Functional Proteomics and Deep Network Interrogation Reveal a Complex Mechanism of Action of Midostaurin in Lung Cancer Cells. PMID:30217950
The Amino Acid Composition of Quadruplex Binding Proteins Reveals a Shared Motif and Predicts New Potential Quadruplex Interactors. PMID:30216987
Analysis of Protein Complexes in the Unicellular Cyanobacterium Cyanothece ATCC 51142. PMID:30216071
Rewiring of cisplatin-resistant bladder cancer cells through epigenetic regulation of genes involved in amino acid metabolism. PMID:30214636
Transcriptomic signature associated with carcinogenesis and aggressiveness of papillary thyroid carcinoma. PMID:30214625
Proteome data of Anopheles stephensi ovary using high-resolution mass spectrometry. PMID:30211266
Multifaceted regulation and functions of replication factor C family in human cancers. PMID:30210909
Identification of Genes and Pathways Involved in Ovarian Epithelial Cancer by Bioinformatics Analysis. PMID:30210623
Epistasis regulates the developmental stability of the mouse craniofacial shape. PMID:30209292
A comparative analysis of label-free liquid chromatography-mass spectrometry liver proteomic profiles highlights metabolic differences between pig breeds. PMID:30208024
Quillaja brasiliensis saponin-based nanoparticulate adjuvants are capable of triggering early immune responses. PMID:30206376
Identification of differentially expressed genes and signaling pathways using bioinformatics in interstitial lung disease due to tyrosine kinase inhibitors targeting the epidermal growth factor receptor. PMID:30203136
T cell immunomodulation by clinically used allogeneic human cancellous bone fragments: a potential novel immunotherapy tool. PMID:30201960
Detection of Functional Overreaching in Endurance Athletes Using Proteomics. PMID:30200480
Targeted UPLC-MS Metabolic Analysis of Human Faeces Reveals Novel Low-Invasive Candidate Markers for Colorectal Cancer. PMID:30200467
A distinct class of antioxidant response elements is consistently activated in tumors with NRF2 mutations. PMID:30195190
Prediction of protein group function by iterative classification on functional relevance network. PMID:30192921
Beneficial Role of Rosuvastatin in Blood-Brain Barrier Damage Following Experimental Ischemic Stroke. PMID:30186167
Ruxolitinib inhibits cyclosporine-induced proliferation of cutaneous squamous cell carcinoma. PMID:30185657
PPARγ/Pgc-1α-Fndc5 pathway up-regulation in gastrocnemius and heart muscle of exercised, branched chain amino acid diet fed mice. PMID:30181762
Insights into archaeal chaperone machinery: a network-based approach. PMID:30178307
Calmodulin Enhances Cryptochrome Binding to INAD in Drosophila Photoreceptors. PMID:30177872
Differentially Tolerized Mouse Antigen Presenting Cells Share a Common miRNA Signature Including Enhanced mmu-miR-223-3p Expression Which Is Sufficient to Imprint a Protolerogenic State. PMID:30174602
Sex dependent impact of gestational stress on predisposition to eating disorders and metabolic disease. PMID:30174229
Identification of hub genes and analysis of prognostic values in pancreatic ductal adenocarcinoma by integrated bioinformatics methods. PMID:30173393
A Smooth-Type, Phage-Resistant Klebsiella pneumoniae Mutant Strain Reveals that OmpC Is Indispensable for Infection by Phage GH-K3. PMID:30171001
The Xenopus animal cap transcriptome: building a mucociliary epithelium. PMID:30165493
Insight into Arthrospira platensis Δ9 desaturase: a key enzyme in poly-unsaturated fatty acid synthesis. PMID:30159640
Differential Proteomic Analysis Predicts Appropriate Applications for the Secretome of Adipose-Derived Mesenchymal Stem/Stromal Cells and Dermal Fibroblasts. PMID:30158987
Co-expression Network Analysis of Biomarkers for Adrenocortical Carcinoma. PMID:30158955
In Vitro Weight-Loaded Cell Models for Understanding Mechanodependent Molecular Pathways Involved in Orthodontic Tooth Movement: A Systematic Review. PMID:30154862
Insights Into de novo Mutation Variation in Lithuanian Exome. PMID:30154829
Wide-Ranging Analysis of MicroRNA Profiles in Sporadic Amyotrophic Lateral Sclerosis Using Next-Generation Sequencing. PMID:30154826
Identification of key genes and pathways using bioinformatics analysis in septic shock children. PMID:30147344
Circulating Biomarkers From the Phase 1 Trial of Sirolimus and Autophagy Inhibition for Patients With Lymphangioleiomyomatosis. PMID:30144422
Utility of serological biomarkers for giant cell arteritis in a large cohort of treatment-naïve patients. PMID:30143961
Global phosphoproteomic analysis identifies SRMS-regulated secondary signaling intermediates. PMID:30140170
Transcriptional targeting of oncogene addiction in medullary thyroid cancer. PMID:30135308
A High-Throughput Candida albicans Two-Hybrid System. PMID:30135223
An impaired hepatic clock system effects lipid metabolism in rats with nephropathy. PMID:30132511
In silico Identification of the Indispensable Quorum Sensing Proteins of Multidrug Resistant Proteus mirabilis. PMID:30131943
Systematic Analysis of Survival-Associated Alternative Splicing Signatures in Gastrointestinal Pan-Adenocarcinomas. PMID:30131306
Thioredoxin-related protein of 14 kDa as a modulator of redox signalling pathways. PMID:30129655
Identification and characterization of histone modification gene family reveal their critical responses to flower induction in apple. PMID:30126363
Functional Linkage of RKIP to the Epithelial to Mesenchymal Transition and Autophagy during the Development of Prostate Cancer. PMID:30115852
The Kaleidoscope of Microglial Phenotypes. PMID:30108586
Molecular characterization of the apoptosis-related SH3RF1 and SH3RF2 genes and their association with exercise performance in Arabian horses. PMID:30107803
Activity-dependent neuroprotective protein deficiency models synaptic and developmental phenotypes of autism-like syndrome. PMID:30106381
Schizosaccharomyces pombe Pol II transcription elongation factor ELL functions as part of a rudimentary super elongation complex. PMID:30102332
Biomarker panels for characterizing microbial community biofilm formation as composite molecular process. PMID:30092027
Genome-wide association study using haplotype alleles for the evaluation of reproductive traits in Nelore cattle. PMID:30089161
Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP. PMID:30087168
Network analysis of inflammatory responses to sepsis by neutrophils and peripheral blood mononuclear cells. PMID:30086151
From hairballs to hypotheses-biological insights from microbial networks. PMID:30085090
Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration of hematopoietic stem cells. PMID:30083817
Contribution of Inhibitor of Differentiation and Estrogenic Endocrine Disruptors to Neurocognitive Disorders. PMID:30081481
Chemical screen identifies a geroprotective role of quercetin in premature aging. PMID:30069858
Transcriptome and metabolome analysis reveal candidate genes and biochemicals involved in tea geometrid defense in Camellia sinensis. PMID:30067831
An automated identification and analysis of ontological terms in gastrointestinal diseases and nutrition-related literature provides useful insights. PMID:30065857
Identification of Potential Key Genes Associated With the Pathogenesis and Prognosis of Gastric Cancer Based on Integrated Bioinformatics Analysis. PMID:30065754
A systematic survey of centrality measures for protein-protein interaction networks. PMID:30064421
Engineering TATA-binding protein Spt15 to improve ethanol tolerance and production in Kluyveromyces marxianus. PMID:30061929
New Insights into the Occurrence of Matrix Metalloproteases -2 and -9 in a Cohort of Breast Cancer Patients and Proteomic Correlations. PMID:30060564
Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy. PMID:30054502
Automatic extraction of gene-disease associations from literature using joint ensemble learning. PMID:30048465
Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming. PMID:30047926
[Molecular networks of hypoxia and neuronal apoptosis in the cochlea]. PMID:30043174
A comparison of heat-stress transcriptome changes between wild-type Arabidopsis pollen and a heat-sensitive mutant harboring a knockout of cyclic nucleotide-gated cation channel 16 (cngc16). PMID:30041596
RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer. PMID:30037330
Functions of Rhotekin, an Effector of Rho GTPase, and Its Binding Partners in Mammals. PMID:30037057
Mapping the Genetic Landscape of Human Cells. PMID:30033366
Metaproteomics reveals associations between microbiome and intestinal extracellular vesicle proteins in pediatric inflammatory bowel disease. PMID:30030445
Abnormal RNA stability in amyotrophic lateral sclerosis. PMID:30030424
Potent and selective effect of the mir-10b inhibitor MN-anti-mir10b in human cancer cells of diverse primary disease origin. PMID:30028875
Identification of the Key MicroRNAs and the miRNA-mRNA Regulatory Pathways in Prostate Cancer by Bioinformatics Methods. PMID:30027097
Distinct Diagnostic and Prognostic Values of Minichromosome Maintenance Gene Expression in Patients with Hepatocellular Carcinoma. PMID:30026832
ProfPPIdb: Pairs of physical protein-protein interactions predicted for entire proteomes. PMID:30020956
Systematic Study of Nucleosome-Displacing Factors in Budding Yeast. PMID:30017582
Kinome-wide identification of phosphorylation networks in eukaryotic proteomes. PMID:30016513
Downregulation of miR‑486‑5p in papillary thyroid carcinoma tissue: A study based on microarray and miRNA sequencing. PMID:30015845
Altered Gene Expression in Prefrontal Cortex of a Fabry Disease Mouse Model. PMID:30013462
Gene expression drives the evolution of dominance. PMID:30013096
Netpredictor: R and Shiny package to perform drug-target network analysis and prediction of missing links. PMID:30012095
Identification and characterization of the bZIP transcription factor family and its expression in response to abiotic stresses in sesame. PMID:30011333
5-Hydroxymethylome in Circulating Cell-free DNA as A Potential Biomarker for Non-small-cell Lung Cancer. PMID:30010036
Bioinformatic identification of key genes and analysis of prognostic values in clear cell renal cell carcinoma. PMID:30008862
Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome. PMID:30008298
Aspirin is Involved in the Cell Cycle Arrest, Apoptosis, Cell Migration, and Invasion of Oral Squamous Cell Carcinoma. PMID:30002310
Diet changes alter paternally inherited epigenetic pattern in male Wild guinea pigs. PMID:29992049
Integrated multifactor analysis explores core dysfunctional modules in autism spectrum disorder. PMID:29989084
Using a Chemical Genetic Screen to Enhance Our Understanding of the Antibacterial Properties of Silver. PMID:29986482
Genome-Wide Changes in Protein Translation Efficiency Are Associated with Autism. PMID:29986017
The prognostic value of differentially expressed CYP3A subfamily members for hepatocellular carcinoma. PMID:29983591
Biomarker Identification from RNA-Seq Data using a Robust Statistical Approach. PMID:29983485
Molecular modeling, docking and protein-protein interaction analysis of MAPK signalling cascade involved in Camalexin biosynthesis in Brassica rapa. PMID:29983484
Influenza A Virus Induces Autophagosomal Targeting of Ribosomal Proteins. PMID:29980615
Thermal proteome profiling in bacteria: probing protein state in vivo. PMID:29980614
An Uncharacterized Member of the Gls24 Protein Superfamily Is a Putative Sensor of Essential Amino Acid Availability in Streptococcus pneumoniae. PMID:29978356
Novel proteome and acetylome of Bemisia tabaci Q in response to Cardinium infection. PMID:29976144
Identification of Critical Genes and Five Prognostic Biomarkers Associated with Colorectal Cancer. PMID:29973580
A novel gene-expression-signature-based model for prediction of response to Tripterysium glycosides tablet for rheumatoid arthritis patients. PMID:29973208
HyPR-MS for Multiplexed Discovery of MALAT1, NEAT1, and NORAD lncRNA Protein Interactomes. PMID:29972301
Patients with early-stage oropharyngeal cancer can be identified with label-free serum proteomics. PMID:29961760
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders. PMID:29951184
Onto2Vec: joint vector-based representation of biological entities and their ontology-based annotations. PMID:29949999
Modeling polypharmacy side effects with graph convolutional networks. PMID:29949996
Network-based association analysis to infer new disease-gene relationships using large-scale protein interactions. PMID:29949603
Site-specific characterization of endogenous SUMOylation across species and organs. PMID:29942033
Prediction of auxin response elements based on data fusion in Arabidopsis thaliana. PMID:29936576
Genomic approaches for the elucidation of genes and gene networks underlying cardiovascular traits. PMID:29934864
Quantitative Crotonylome Analysis Expands the Roles of p300 in the Regulation of Lysine Crotonylation Pathway. PMID:29932303
Computational Methods for Predicting Protein-Protein Interactions Using Various Protein Features. PMID:29927082
Elevated T cell levels in peripheral blood predict poor clinical response following rituximab treatment in new-onset type 1 diabetes. PMID:29925930
Identification of hepatic protein-protein interaction targets for betaine homocysteine S-methyltransferase. PMID:29924862
Hub Protein Controversy: Taking a Closer Look at Plant Stress Response Hubs. PMID:29922309
Co-Expression Network Analysis of AMPK and Autophagy Gene Products during Adipocyte Differentiation. PMID:29921805
Structural insights and characterization of human Npas4 protein. PMID:29915698
Autophagy Impairment Is Associated With Increased Inflammasome Activation and Reversal Reaction Development in Multibacillary Leprosy. PMID:29915584
Global analysis of threonine metabolism genes unravel key players in rice to improve the abiotic stress tolerance. PMID:29915249
Hyperstimulation of CaSR in human MSCs by biomimetic apatite inhibits endochondral ossification via temporal down-regulation of PTH1R. PMID:29915064
Biochemical pathway analysis of gastric atrophy. PMID:29910852
Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. PMID:29907695
Weighted gene co‑expression network analysis in identification of key genes and networks for ischemic‑reperfusion remodeling myocardium. PMID:29901145
Proteome data of Anopheles stephensi hemolymph using high resolution mass spectrometry. PMID:29900324
A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes. PMID:29899353
Transgenerational inheritance of chronic adolescent stress: Effects of stress response and the amygdala transcriptome. PMID:29896789
Development Of A Three-Gene Prognostic Signature For Hepatitis B Virus Associated Hepatocellular Carcinoma Based On Integrated Transcriptomic Analysis. PMID:29896284
Expression and regulation of the Pseudomonas aeruginosa hibernation promoting factor. PMID:29885070
OmicsNet: a web-based tool for creation and visual analysis of biological networks in 3D space. PMID:29878180
Using Regularization to Infer Cell Line Specificity in Logical Network Models of Signaling Pathways. PMID:29872402
An integrated analysis of key microRNAs, regulatory pathways and clinical relevance in bladder cancer. PMID:29872319
Cell Lysate Microarray for Mapping the Network of Genetic Regulators for Histone Marks. PMID:29871872
Temporal profiling of redox-dependent heterogeneity in single cells. PMID:29869985
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP. PMID:29868516
Host Interaction Analysis of PA-N155 and PA-N182 in Chicken Cells Reveals an Essential Role of UBA52 for Replication of H5N1 Avian Influenza Virus. PMID:29867845
What Makes the Harderian Gland Transcriptome Different From Other Chicken Immune Tissues? A Gene Expression Comparative Analysis. PMID:29867543
KIAA0100 Modulates Cancer Cell Aggression Behavior of MDA-MB-231 through Microtubule and Heat Shock Proteins. PMID:29867023
Effects of perfluorooctane sulfonate on genes controlling hepatic fatty acid metabolism in livers of chicken embryos. PMID:29860686
Human long intrinsically disordered protein regions are frequent targets of positive selection. PMID:29858274
Protein Expression Profile of Twenty-Week-Old Diabetic db/db and Non-Diabetic Mice Livers: A Proteomic and Bioinformatic Analysis. PMID:29857581
Network Pharmacology-Based Approach to Investigate the Mechanisms of Hedyotis diffusa Willd. in the Treatment of Gastric Cancer. PMID:29853970
Quantitative proteomic characterization and comparison of T helper 17 and induced regulatory T cells. PMID:29851958
Three-lncRNA signature is a potential prognostic biomarker for pancreatic adenocarcinoma. PMID:29849937
CBD: a biomarker database for colorectal cancer. PMID:29846545
Mapping Anopheles stephensi midgut proteome using high-resolution mass spectrometry. PMID:29845101
Identifying miRNA and gene modules of colon cancer associated with pathological stage by weighted gene co-expression network analysis. PMID:29844680
HMGB1 released by irradiated tumor cells promotes living tumor cell proliferation via paracrine effect. PMID:29844348
Prognostic Value of RNASEH2A-, CDK1-, and CD151-Related Pathway Gene Profiling for Kidney Cancers. PMID:29843367
Cdc48-like protein of actinobacteria (Cpa) is a novel proteasome interactor in mycobacteria and related organisms. PMID:29809155
No wisdom in the crowd: genome annotation in the era of big data - current status and future prospects. PMID:29806194
The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells. PMID:29805737
The conserved RNA recognition motif and C3H1 domain of the Not4 ubiquitin ligase regulate in vivo ligase function. PMID:29802328
The challenge of drug resistance in cancer treatment: a current overview. PMID:29799080
Extracellular RNA profiles with human age. PMID:29797538
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. PMID:29789581
Integration of protein phosphorylation, acetylation, and methylation data sets to outline lung cancer signaling networks. PMID:29789295
Analysis of antibiotics resistant genes in different strains of Staphylococcus aureus. PMID:29785070
Integrated proteomics, genomics, metabolomics approaches reveal oxalic acid as pathogenicity factor in Tilletia indica inciting Karnal bunt disease of wheat. PMID:29777151
Molecular characterization of physis tissue by RNA sequencing. PMID:29775757
A Five-microRNA Signature for Survival Prognosis in Pancreatic Adenocarcinoma based on TCGA Data. PMID:29769534
Systems Pharmacology-Based Approach of Connecting Disease Genes in Genome-Wide Association Studies with Traditional Chinese Medicine. PMID:29765977
Proteomic screening identifies the zonula occludens protein ZO-1 as a new partner for ADAM12 in invadopodia-like structures. PMID:29765546
Comprehensive and integrative analysis identifies microRNA-106 as a novel non-invasive biomarker for detection of gastric cancer. PMID:29764446
Genomics and Epigenomics of Congenital Heart Defects: Expert Review and Lessons Learned in Africa. PMID:29762087
Lung-Resident Mesenchymal Stromal Cells Reveal Transcriptional Dynamics of Lung Development in Preterm Infants. PMID:29757681
Integrative Analysis Identifies Genetic Variants Associated With Autoimmune Diseases Affecting Putative MicroRNA Binding Sites. PMID:29755505
RNAi-Based Identification of Gene-Specific Nuclear Cofactor Networks Regulating Interleukin-1 Target Genes. PMID:29755455
Deconvolution of Human Brain Cell Type Transcriptomes Unraveled Microglia-Specific Potential Biomarkers. PMID:29755398
Identification of a 5‑lncRNA signature‑based risk scoring system for survival prediction in colorectal cancer. PMID:29749517
Proteomic Investigation to Identify Anticancer Targets of Nemopilema nomurai Jellyfish Venom in Human Hepatocarcinoma HepG2 Cells. PMID:29748501
Profiling the Serum Protein Corona of Fibrillar Human Islet Amyloid Polypeptide. PMID:29746093
PPI network analyses of human WD40 protein family systematically reveal their tendency to assemble complexes and facilitate the complex predictions. PMID:29745845
MEGADOCK-Web: an integrated database of high-throughput structure-based protein-protein interaction predictions. PMID:29745830
Bioinformatic analysis and identification of potential prognostic microRNAs and mRNAs in thyroid cancer. PMID:29740512
Expression of the Long Intergenic Non-Protein Coding RNA 665 (LINC00665) Gene and the Cell Cycle in Hepatocellular Carcinoma Using The Cancer Genome Atlas, the Gene Expression Omnibus, and Quantitative Real-Time Polymerase Chain Reaction. PMID:29728556
miR-205 regulates the proliferation and invasion of ovarian cancer cells via suppressing PTEN/SMAD4 expression. PMID:29725462
Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer. PMID:29721183
Role of Selenof as a Gatekeeper of Secreted Disulfide-Rich Glycoproteins. PMID:29719252
iPath3.0: interactive pathways explorer v3. PMID:29718427
Elevated Glucose Levels Preserve Glucose Uptake, Hyaluronan Production, and Low Glutamate Release Following Interleukin-1β Stimulation of Differentiated Chondrocytes. PMID:29701083
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies. PMID:29695774
Identification of Key Candidate Genes and Pathways in Endometrial Cancer by Integrated Bioinformatical Analysis. PMID:29693365
Genome-Wide Association Analyses Highlight the Potential for Different Genetic Mechanisms for Litter Size Among Sheep Breeds. PMID:29692799
Alternative polyadenylation drives genome-to-phenome information detours in the AMPKα1 and AMPKα2 knockout mice. PMID:29691479
Differential protein expression and post-translational modifications in metronidazole-resistant Giardia duodenalis. PMID:29688452
SILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast. PMID:29688323
Placental miR-340 mediates vulnerability to activity based anorexia in mice. PMID:29686286
Genome-wide RNAi Screening to Identify Host Factors That Modulate Oncolytic Virus Therapy. PMID:29683442
Comparative gel-based proteomic analysis of chemically crosslinked complexes in dystrophic skeletal muscle. PMID:29679381
Quantitative shotgun proteomics distinguishes wound-healing biomarker signatures in common carp skin mucus in response to Ichthyophthirius multifiliis. PMID:29678203
Cardiomyocytes have mosaic patterns of protein expression. PMID:29677652
Viral Induced Oxidative and Inflammatory Response in Alzheimer's Disease Pathogenesis with Identification of Potential Drug Candidates: A Systematic Review using Systems Biology Approach. PMID:29676229
Identification of Poly-N-Acetyllactosamine-Carrying Glycoproteins from HL-60 Human Promyelocytic Leukemia Cells Using a Site-Specific Glycome Analysis Method, Glyco-RIDGE. PMID:29675740
Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity. PMID:29671950
Annotating activation/inhibition relationships to protein-protein interactions using gene ontology relations. PMID:29671402
ANLN functions as a key candidate gene in cervical cancer as determined by integrated bioinformatic analysis. PMID:29670400
Effect of Larval Nutrition on Maternal mRNA Contribution to the Drosophila Egg. PMID:29666195
Transcriptome and proteome profiling reveals stress-induced expression signatures of imiquimod-treated Tasmanian devil facial tumor disease (DFTD) cells. PMID:29662615
Analysis of Human Nuclear Protein Complexes by Quantitative Mass Spectrometry Profiling. PMID:29655301
Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration. PMID:29642001
"Exosomics"-A Review of Biophysics, Biology and Biochemistry of Exosomes With a Focus on Human Breast Milk. PMID:29636770
Salivary proteome profiling of oral squamous cell carcinoma in a Hungarian population. PMID:29632809
Profiling of Long Non-coding RNAs and mRNAs by RNA-Sequencing in the Hippocampi of Adult Mice Following Propofol Sedation. PMID:29628875
High-throughput mouse phenomics for characterizing mammalian gene function. PMID:29626206
Integrating images from multiple microscopy screens reveals diverse patterns of change in the subcellular localization of proteins. PMID:29620521
A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer. PMID:29619072
Screening of Human Proteins for Fluoride and Aluminum Binding. PMID:29618902
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. PMID:29617664
A comprehensive analysis of the predicted targets of miR-642b-3p associated with the long non-coding RNA HOXA11-AS in NSCLC cells. PMID:29616096
Bioinformatic analysis of prognostic value of ZW10 interacting protein in lung cancer. PMID:29615843
Lipid accumulation in human breast cancer cells injured by iron depletors. PMID:29615075
A 35-gene signature discriminates between rapidly- and slowly-progressing glioblastoma multiforme and predicts survival in known subtypes of the cancer. PMID:29614978
Systematic Evaluation of Molecular Networks for Discovery of Disease Genes. PMID:29605183
Shifts in the Gut Metabolome and Clostridium difficile Transcriptome throughout Colonization and Infection in a Mouse Model. PMID:29600278
Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans. PMID:29598825
Nasopharyngeal Carcinoma Protein Interaction Mapping Analysis via Proteomic Approaches. PMID:29582644
Proteomic analysis of plasma extracellular vesicles reveals mitochondrial stress upon HTLV-1 infection. PMID:29581472
Gene expression profiles of ion channels and receptors in mouse resistance arteries: Effects of cell type, vascular bed, and age. PMID:29577514
NOD2- and disease-specific gene expression profiles of peripheral blood mononuclear cells from Crohn's disease patients. PMID:29568200
Calcium-Dependent Protein Kinase Family Genes Involved in Ethylene-Induced Natural Rubber Production in Different Hevea brasiliensis Cultivars. PMID:29565813
Association of Proteomics Changes with Al-Sensitive Root Zones in Switchgrass. PMID:29565292
Study of Imidazolium Salt Derivatives as PIK3CA Inhibitors Using a Comprehensive in Silico Method. PMID:29562629
Small molecules capable of activating DNA methylation-repressed genes targeted by the p38 mitogen-activated protein kinase pathway. PMID:29559556
Experimental evolution and proximate mechanisms in biology. PMID:29552649
Expression profiling analysis of autophagy-related genes in perineural invasion of cutaneous squamous cell carcinoma. PMID:29552123
BIOPYDB: A Dynamic Human Cell Specific Biochemical Pathway Database with Advanced Computational Analyses Platform. PMID:29547394
Alpha-oxoglutarate inhibits the proliferation of immortalized normal bladder epithelial cells via an epigenetic switch involving ARID1A. PMID:29540744
MPO Promoter Polymorphism rs2333227 Enhances Malignant Phenotypes of Colorectal Cancer by Altering the Binding Affinity of AP-2α. PMID:29540402
Identification of key differentially expressed genes associated with non‑small cell lung cancer by bioinformatics analyses. PMID:29532892
Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis. PMID:29530978
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay. PMID:29528287
Whole transcriptome profiling of Late-Onset Alzheimer's Disease patients provides insights into the molecular changes involved in the disease. PMID:29523845
Genome-wide map of proximity linkage to renin proximal promoter in rat. PMID:29521603
Identification of key genes of papillary thyroid cancer using integrated bioinformatics analysis. PMID:29520684
Anticancer activity of biogenerated silver nanoparticles: an integrated proteomic investigation. PMID:29515763
Changes in chromatin accessibility between Arabidopsis stem cells and mesophyll cells illuminate cell type-specific transcription factor networks. PMID:29513366
Protein interaction mapping interpretation of none alcoholic fatty liver disease model of rats after fat diet feeding. PMID:29511485
Evaluation of involved proteins in colon adenocarcinoma: an interactome analysis. PMID:29511483
A recombinant Fasciola gigantica 14-3-3 epsilon protein (rFg14-3-3e) modulates various functions of goat peripheral blood mononuclear cells. PMID:29510740
Consequences of early life stress on genomic landscape of H3K4me3 in prefrontal cortex of adult mice. PMID:29504911
Genotypic effect of a mutation of the MYBPC3 gene and two phenotypes with different patterns of inheritance. PMID:29493010
The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock. PMID:29491349
Identification and characterization of microRNAs in the intestinal tissues of sheep (Ovis aries). PMID:29489866
Ten hub genes associated with progression and prognosis of pancreatic carcinoma identified by co-expression analysis. PMID:29483831
Uncovering the genetic lesions underlying the most severe form of Hirschsprung disease by whole-genome sequencing. PMID:29483666
Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease. PMID:29483513
A systems biology approach to predictive developmental neurotoxicity of a larvicide used in the prevention of Zika virus transmission. PMID:29476864
Distinct expression of CDCA3, CDCA5, and CDCA8 leads to shorter relapse free survival in breast cancer patient. PMID:29467944
Spina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice. PMID:29463853
Transcriptomic and Proteomic Profiling Revealed High Proportions of Odorant Binding and Antimicrobial Defense Proteins in Olfactory Tissues of the House Mouse. PMID:29459883
Metabolic Profile of Oral Squamous Carcinoma Cell Lines Relies on a Higher Demand of Lipid Metabolism in Metastatic Cells. PMID:29456966
Five Novel Oncogenic Signatures Could Be Utilized as AFP-Related Diagnostic Biomarkers for Hepatocellular Carcinoma Based on Next-Generation Sequencing. PMID:29442275
Profiling of Human Molecular Pathways Affected by Retrotransposons at the Level of Regulation by Transcription Factor Proteins. PMID:29441061
Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications. PMID:29441009
Redox responses are preserved across muscle fibres with differential susceptibility to aging. PMID:29438851
Comprehensive characterization of cancer genes in hepatocellular carcinoma genomes. PMID:29434842
Identification of genomic expression differences between right-sided and left-sided colon cancer based on bioinformatics analysis. PMID:29430186
Signatures of Altered Gene Expression in Dorsal Root Ganglia of a Fabry Disease Mouse Model. PMID:29422837
Construction and analysis for differentially expressed long non-coding RNAs and MicroRNAs mediated competing endogenous RNA network in colon cancer. PMID:29420609
Embryonic stem cell-derived cardiomyocytes for the treatment of doxorubicin-induced cardiomyopathy. PMID:29402309
All-Round Manipulation of the Actin Cytoskeleton by HIV. PMID:29401736
Identification of molecular pathways and candidate genes associated with cocks' comb size trait by genome-wide transcriptome analysis. PMID:29386544
Target discovery screens using pooled shRNA libraries and next-generation sequencing: A model workflow and analytical algorithm. PMID:29385199
Screening of Potential Genes and Transcription Factors of Postoperative Cognitive Dysfunction via Bioinformatics Methods. PMID:29374768
Cerebrospinal fluid chemokine patterns in children with enterovirus 71-related encephalitis. PMID:29374213
Identification of a Common Different Gene Expression Signature in Ischemic Cardiomyopathy. PMID:29361784
Fasting and Fast Food Diet Play an Opposite Role in Mice Brain Aging. PMID:29353457
Preservation Method and Phosphate Buffered Saline Washing Affect the Acute Myeloid Leukemia Proteome. PMID:29351208
The Role of Cadaverine Synthesis on Pneumococcal Capsule and Protein Expression. PMID:29351189
Integrated Analyses Reveal Overexpressed Notch1 Promoting Porcine Satellite Cells' Proliferation through Regulating the Cell Cycle. PMID:29337929
The PEG-responding desiccome of the alder microsymbiont Frankia alni. PMID:29335550
Population-dependent Intron Retention and DNA Methylation in Breast Cancer. PMID:29330282
Combined analysis of gene expression and genome binding profiles identified potential therapeutic targets of ciclopirox in Ewing sarcoma. PMID:29328472
Identification and Characterization of Sindbis Virus RNA-Host Protein Interactions. PMID:29321325
In Silico Characterization and Functional Validation of Cell Wall Modification Genes Imparting Waterlogging Tolerance in Maize. PMID:29317803
Assessing the Performances of Protein Function Prediction Algorithms from the Perspectives of Identification Accuracy and False Discovery Rate. PMID:29316706
Prognostic Significance of Activated Leukocyte Cell Adhesion Molecule (ALCAM) in Association with Promoter Methylation of the ALCAM Gene in Breast Cancer. PMID:29315254
Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer. PMID:29306329
Simultaneous inference of phenotype-associated genes and relevant tissues from GWAS data via Bayesian integration of multiple tissue-specific gene networks. PMID:29300920
A database of human genes and a gene network involved in response to tick-borne encephalitis virus infection. PMID:29297316
Twist1 regulates embryonic hematopoietic differentiation through binding to Myb and Gata2 promoter regions. PMID:29296814
Non-canonical Wnt signaling regulates neural stem cell quiescence during homeostasis and after demyelination. PMID:29296000
Protein-Protein Interaction Network Analysis for a Biomarker Panel Related to Human Esophageal Adenocarcinoma. PMID:29286604
Preclinical efficacy and immunogenicity assessment to show that a chimeric Plasmodium falciparum UB05-09 antigen could be a malaria vaccine candidate. PMID:29284177
Integrative analysis of lncRNAs and miRNAs with coding RNAs associated with ceRNA crosstalk network in triple negative breast cancer. PMID:29276392
Restoration of type 1 iodothyronine deiodinase expression in renal cancer cells downregulates oncoproteins and affects key metabolic pathways as well as anti-oxidative system. PMID:29272308
Enhancing the Promise of Drug Repositioning through Genetics. PMID:29270124
Cell Cycle Model System for Advancing Cancer Biomarker Research. PMID:29269772
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1. PMID:29269732
Phyletic Distribution and Lineage-Specific Domain Architectures of Archaeal Two-Component Signal Transduction Systems. PMID:29263101
DanHong injection targets endothelin receptor type B and angiotensin II receptor type 1 in protection against cardiac hypertrophy. PMID:29262570
Sustained activation of the AKT/mTOR and MAP kinase pathways mediate resistance to the Src inhibitor, dasatinib, in thyroid cancer. PMID:29262541
The retina/RPE proteome in chick myopia and hyperopia models: Commonalities with inherited and age-related ocular pathologies. PMID:29259393
Bioinformatics analysis of differentially expressed gene profiles associated with systemic lupus erythematosus. PMID:29257335
A Genome-Wide Association Study and Complex Network Identify Four Core Hub Genes in Bipolar Disorder. PMID:29257106
Weighted Gene Co-expression Network Analysis Identifies FKBP11 as a Key Regulator in Acute Aortic Dissection through a NF-kB Dependent Pathway. PMID:29255427
Generating a Tolerogenic Cell Therapy Knowledge Graph from Literature. PMID:29238346
Relative Quantitative Proteomic Analysis of Brucella abortus Reveals Metabolic Adaptation to Multiple Environmental Stresses. PMID:29238329
Functional network community detection can disaggregate and filter multiple underlying pathways in enrichment analyses. PMID:29218878
The transcription factors Hsf1 and Msn2 of thermotolerant Kluyveromyces marxianus promote cell growth and ethanol fermentation of Saccharomyces cerevisiae at high temperatures. PMID:29213328
Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain. PMID:29207277
Repository corticotrophin injection exerts direct acute effects on human B cell gene expression distinct from the actions of glucocorticoids. PMID:29205315
Duchenne Muscular Dystrophy (DMD) Protein-Protein Interaction Mapping. PMID:29201118
Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome. PMID:29196558
Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA). PMID:29183982
FunCoup 4: new species, data, and visualization. PMID:29165593
RNA metabolism is the primary target of formamide in vivo. PMID:29162938
A 16-gene signature predicting prognosis of patients with oral tongue squamous cell carcinoma. PMID:29158988
Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data. PMID:29155944
Ketamine's antidepressant effect is mediated by energy metabolism and antioxidant defense system. PMID:29150633
Towards a Unified Understanding of Lithium Action in Basic Biology and its Significance for Applied Biology. PMID:29127487
PFI1785w: A highly conserved protein associated with pregnancy associated malaria. PMID:29121643
The UCSC Genome Browser database: 2018 update. PMID:29106570
Bioinformatics on a national scale: an example from Switzerland. PMID:29106442
Genome-wide identification and expression analysis of calmodulin-like (CML) genes in Chinese cabbage (Brassica rapa L. ssp. pekinensis). PMID:29096605
Network-Driven Proteogenomics Unveils an Aging-Related Imbalance in the Olfactory IκBα-NFκB p65 Complex Functionality in Tg2576 Alzheimer's Disease Mouse Model. PMID:29077059
Single-cell analysis identifies cellular markers of the HIV permissive cell. PMID:29073251
Identification of molecular alterations in leukocytes from gene expression profiles of peripheral whole blood of Alzheimer's disease. PMID:29070791
Investigating transcription factor synergism in humans. PMID:29069301
Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells. PMID:29066743
BioPlex Display: An Interactive Suite for Large-Scale AP-MS Protein-Protein Interaction Data. PMID:29054129
Integrated genomic characterization of cancer genes in glioma. PMID:29046615
The polyglutamine protein ataxin-3 enables normal growth under heat shock conditions in the methylotrophic yeast Pichia pastoris. PMID:29042637
20 years of the SMART protein domain annotation resource. PMID:29040681
Anti-CRISPRdb: a comprehensive online resource for anti-CRISPR proteins. PMID:29036676
A Compendium of Co-regulated Protein Complexes in Breast Cancer Reveals Collateral Loss Events. PMID:29032073
Signatures of positive selection reveal a universal role of chromatin modifiers as cancer driver genes. PMID:29030609
Plasmodium falciparum specific helicase 3 is nucleocytoplasmic protein and unwinds DNA duplex in 3' to 5' direction. PMID:29030567
Functional Impact of Chromatin Remodeling Gene Mutations and Predictive Signature for Therapeutic Response in Bladder Cancer. PMID:28970362
Identification of candidate genes associated with triple negative breast cancer. PMID:28966727
Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis. PMID:28945738
Computational Approaches to Identify Genetic Interactions for Cancer Therapeutics. PMID:28941356
Detecting gene subnetworks under selection in biological pathways. PMID:28934485
A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. PMID:28892059
SERPING1 mRNA overexpression in monocytes from HIV+ patients. PMID:28889214
Periostin and its interacting proteins in the construction of extracellular architectures. PMID:28887577
Novel Insights into the Adipokinome of Obese and Obese/Diabetic Mouse Models. PMID:28885548
An integrated analysis for long noncoding RNAs and microRNAs with the mediated competing endogenous RNA network in papillary renal cell carcinoma. PMID:28860812
Phosphoproteomic Analysis Reveals the Importance of Kinase Regulation During Orbivirus Infection. PMID:28851738
Association and interaction of myopia with SNP markers rs13382811 and rs6469937 at ZFHX1B and SNTB1 in Han Chinese and European populations. PMID:28848321
Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib. PMID:28842319
Proteomic analysis of protein phosphatase Z1 from Candida albicans. PMID:28837603
DNA helix: the importance of being AT-rich. PMID:28836096
Pervasive coexpression of spatially proximal genes is buffered at the protein level. PMID:28835372
Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing. PMID:28769105
Dynamic scaffolds for neuronal signaling: in silico analysis of the TANC protein family. PMID:28754924
Oral squamous cell cancer protein-protein interaction network interpretation in comparison to esophageal adenocarcinoma. PMID:28744358
Multiple correlation analyses revealed complex relationship between DNA methylation and mRNA expression in human peripheral blood mononuclear cells. PMID:28735351
UCSF ChimeraX: Meeting modern challenges in visualization and analysis. PMID:28710774
The CINSARC signature as a prognostic marker for clinical outcome in multiple neoplasms. PMID:28710396
TRAIL, Wnt, Sonic Hedgehog, TGFβ, and miRNA Signalings Are Potential Targets for Oral Cancer Therapy. PMID:28708091
Interferon γ induced compositional changes in human bone marrow derived mesenchymal stem/stromal cells. PMID:28694743
Intra-articular injection of a substance P inhibitor affects gene expression in a joint contracture model. PMID:28671282
Exploring Wound-Healing Genomic Machinery with a Network-Based Approach. PMID:28635674
Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes. PMID:28566371
Label-Free Quantitative Proteomic Analysis of Chitosan Oligosaccharide-Treated Rice Infected with Southern Rice Black-Streaked Dwarf Virus. PMID:28524115
Quantitative proteomics profiling reveals activation of mTOR pathway in trastuzumab resistance. PMID:28507275
microRNA-125a-3p is regulated by MyD88 in Legionella pneumophila infection and targets NTAN1. PMID:28445535
Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains. PMID:28404772
Introducing crucial protein panel of gastric adenocarcinoma disease. PMID:28331560
Protein Kinase CK2: Intricate Relationships within Regulatory Cellular Networks. PMID:28273877
Introduction of inflammatory bowel disease biomarkers panel using protein-protein interaction (PPI) network analysis. PMID:28224022
Exome analysis of Smith-Magenis-like syndrome cohort identifies de novo likely pathogenic variants. PMID:28213671
A comprehensive software suite for protein family construction and functional site prediction. PMID:28182651 -
STRING v9.1: protein-protein interaction networks, with increased coverage and integration
PubMed citations: 2019.
2019 articles citing: STRING v9.1: protein-protein interaction networks, with increased coverage and integration
Identifying the Antitumor Effects of Curcumin on Lung Adenocarcinoma Using Comprehensive Bioinformatics Analysis. PMID:35910781
Four-gene signature predicting overall survival and immune infiltration in hepatocellular carcinoma by bioinformatics analysis with RT‒qPCR validation. PMID:35907846
STAT3 and NTRK2 Genes Predicted by the Bioinformatics Approach May Play Important Roles in the Pathogenesis of Multiple Sclerosis and Obsessive-Compulsive Disorder. PMID:35887540
Mutational Signature and Integrative Genomic Analysis of Human Papillomavirus-Associated Penile Squamous Cell Carcinomas from Latin American Patients. PMID:35884575
Escherichia coli transcription factors of unknown function: sequence features and possible evolutionary relationships. PMID:35880217
Comprehensive Analysis of TRIM Family Genes in Hepatitis Virus B-Related Hepatoma Carcinoma. PMID:35873464
Proteomics data analysis using multiple statistical approaches identified proteins and metabolic networks associated with sucrose accumulation in sugarcane. PMID:35869434
Predicting protein network topology clusters from chemical structure using deep learning. PMID:35841114
Identification and Validation of Candidate Gene Module Along With Immune Cells Infiltration Patterns in Atherosclerosis Progression to Plaque Rupture via Transcriptome Analysis. PMID:35811739
Identification of Potential miRNA-mRNA Regulatory Network in Denervated Muscular Atrophy by Bioinformatic Analysis. PMID:35800215
Investigation of the Pharmacological Effect and Mechanism of Jinbei Oral Liquid in the Treatment of Idiopathic Pulmonary Fibrosis Using Network Pharmacology and Experimental Validation. PMID:35784749
Comprehensive Effects of Flowering Locus T-Mediated Stem Growth in Tobacco. PMID:35783923
Transcriptome Integration Analysis at Different Embryonic Ages Reveals Key lncRNAs and mRNAs for Chicken Skeletal Muscle. PMID:35782545
Dysregulation of Neuropeptide and Tau Peptide Signatures in Human Alzheimer's Disease Brain. PMID:35758417
Link Prediction on Complex Networks: An Experimental Survey. PMID:35754861
Transcriptome Profiling Reveals Genes Related to Sex Determination and Differentiation in Sugarcane Borer (Chilo sacchariphagus Bojer). PMID:35735837
Identification of Differentially Expressed Genes and miRNAs for Ulcerative Colitis Using Bioinformatics Analysis. PMID:35719390
Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis. PMID:35692536
Genome-wide identification and characterization of glutathione S-transferase gene family in Musa acuminata L. AAA group and gaining an insight to their role in banana fruit development. PMID:35689012
HOPX: A Unique Homeodomain Protein in Development and Tumor Suppression. PMID:35681746
Evaluating the Immune Response in Treatment-Naive Hospitalised Patients With Influenza and COVID-19. PMID:35663963
Label-Free Quantitative Proteomics Unravel the Impacts of Salt Stress on Dendrobium huoshanense. PMID:35646023
Identification of microRNAs in the Lyme Disease Vector Ixodes scapularis. PMID:35628370
Genome-Wide Identification of the SAMS Gene Family in Upland Cotton (Gossypium hirsutum L.) and Expression Analysis in Drought Stress Treatments. PMID:35627245
Transcriptome analysis of eutopic endometrial stromal cells in women with adenomyosis by RNA-sequencing. PMID:35603555
NUF2 Is a Potential Immunological and Prognostic Marker for Non-Small-Cell Lung Cancer. PMID:35600043
In-depth proteomics characterization of ∆Np73 effectors identifies key proteins with diagnostic potential implicated in lymphangiogenesis, vasculogenesis and metastasis in colorectal cancer. PMID:35586989
Visual barcodes for clonal-multiplexing of live microscopy-based assays. PMID:35585055
Potential mechanisms of Qili Qiangxin capsule to prevent pulmonary arterial hypertension based on network pharmacology analysis in a rat model. PMID:35571420
2D-DIGE based proteome analysis of wheat-Thinopyrum intermedium 7XL/7DS translocation line under drought stress. PMID:35568798
Consensus molecular subtype differences linking colon adenocarcinoma and obesity revealed by a cohort transcriptomic analysis. PMID:35560039
Anti-POSTN and Anti-TIMP1 Autoantibodies as Diagnostic Markers in Esophageal Squamous Cell Carcinoma. PMID:35559040
Identification of Hub Genes Associated With Non-alcoholic Steatohepatitis Using Integrated Bioinformatics Analysis. PMID:35559030
Multitranscriptome analyses of keloid fibroblasts reveal the role of the HIF-1α/HOXC6/ERK axis in keloid development. PMID:35547861
Characterization of Immune-Related Genes and Immune Infiltration Features in Epilepsy by Multi-Transcriptome Data. PMID:35547834
Text mining for identification of biological entities related to antibiotic resistant organisms. PMID:35539017
Identification of Prognostic Biomarkers for Glioblastoma Based on Transcriptome and Proteome Association Analysis. PMID:35538679
Oncogenic ACSM1 in prostate cancer is through metabolic and extracellular matrix-receptor interaction signaling pathways. PMID:35530294
A Six-Gene Risk Model Based on the Immune Score Reveals Prognosis in Intermediate-Risk Acute Myeloid Leukemia. PMID:35528167
Serum Antigenome Profiling Reveals Diagnostic Models for Rheumatoid Arthritis. PMID:35514972
Analysis of the different characteristics between omental preadipocytes and differentiated white adipocytes using bioinformatics methods. PMID:35499169
Identification of key candidate genes and biological pathways in the synovial tissue of patients with rheumatoid arthritis. PMID:35495609
Comprehensive analysis of DNA methylation for periodontitis. PMID:35491409
Identification of Molecular Correlations Between DHRS4 and Progressive Neurodegeneration in Amyotrophic Lateral Sclerosis By Gene Co-Expression Network Analysis. PMID:35479082
Glycation modulates glutamatergic signaling and exacerbates Parkinson's disease-like phenotypes. PMID:35468899
In Silico Analysis of the L-2-Hydroxyglutarate Dehydrogenase Gene Mutations and Their Biological Impact on Disease Etiology. PMID:35456504
In Silico Analysis Identified Putative Pathogenic Missense nsSNPs in Human SLITRK1 Gene. PMID:35456478
Multi-omics integration and interactomics reveals molecular networks and regulators of the beneficial effect of yoga and exercise. PMID:35444372
Epithelial-Mesenchymal Transition-Based Gene Signature and Distinct Molecular Subtypes for Predicting Clinical Outcomes in Breast Cancer. PMID:35386860
An Insight Into the microRNA Profile of the Ectoparasitic Mite Varroa destructor (Acari: Varroidae), the Primary Vector of Honey Bee Deformed Wing Virus. PMID:35372101
Bioinformatics Analysis Reveals Cell Cycle-Related Gene Upregulation in Ascending Aortic Tissues From Murine Models. PMID:35356426
Screening of Potential Key Biomarkers for Ewing Sarcoma: Evidence from Gene Array Analysis. PMID:35342299
Bioinformatics Analysis and Identification of Potential Genes Associated with Pathogenesis and Prognosis of Gastric Cancer. PMID:35325407
Identification of the TF-miRNA-mRNA co-regulatory networks involved in sepsis. PMID:35322335
Integrated Analysis of miRNA and mRNA Expression Profiles Reveals the Molecular Mechanism of Posttraumatic Stress Disorder and Therapeutic Drugs. PMID:35300145
Identification of hub genes and pathways in bladder cancer using bioinformatics analysis. PMID:35291419
Exploring the Communal Pathogenesis, Ferroptosis Mechanism, and Potential Therapeutic Targets of Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy via a Microarray Data Analysis. PMID:35282347
Evaluation of the Prognostic Relevance of Differential Claudin Gene Expression Highlights Claudin-4 as Being Suppressed by TGFβ1 Inhibitor in Colorectal Cancer. PMID:35281827
Systematic understanding of anti-tumor mechanisms of Tamarixetin through network and experimental analyses. PMID:35273218
Investigation of Roles of TaTALE Genes during Development and Stress Response in Bread Wheat. PMID:35270056
GGT5 Is an Independent Prognostic Biomarker in Stomach Adenocarcinoma. PMID:35257007
Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2. PMID:35246634
Identifying protein function and functional links based on large-scale co-occurrence patterns. PMID:35239724
Genome-wide analysis of sucrose synthase family in soybean and their expression in response to abiotic stress and seed development. PMID:35213642
PREGO: A Literature and Data-Mining Resource to Associate Microorganisms, Biological Processes, and Environment Types. PMID:35208748
Identification of Potential Immune Checkpoint Inhibitor Targets in Gliomas via Bioinformatic Analyses. PMID:35198632
Increased Expression of YAP Inhibited the Autophagy Level by Upregulating mTOR Signal in the Eutopic ESCs of Endometriosis. PMID:35173685
PsGSTF3, an Anthocyanin-Related Glutathione S-Transferase Gene, Is Essential for Petal Coloration in Tree Peony. PMID:35163347
Systematic analysis of alterations in the ubiquitin proteolysis system reveals its contribution to driver mutations in cancer. PMID:35121836
Comprehensive analysis reveals a four-gene signature in colorectal cancer. PMID:35117487
Comprehensive analysis reveals novel gene signature in head and neck squamous cell carcinoma: predicting is associated with poor prognosis in patients. PMID:35117201
Helicase lymphoid-specifics and selenoprotein P1 are potential candidate genes in the progression and prognosis of lung adenocarcinoma. PMID:35116990
Identification of hub genes in key hallmarks of ovarian cancer via bioinformatics analysis. PMID:35116413
Transcriptome analysis of the effect of a novel human serine protease inhibitor SPINK13 on gene expression in MHCC97-H cells. PMID:35116303
Characterization of an Aging-Based Diagnostic Gene Signature and Molecular Subtypes With Diverse Immune Infiltrations in Atherosclerosis. PMID:35096968
Exploration of the Role of Serine Proteinase Inhibitor A3 in Alcohol Dependence Using Gene Expression Omnibus Database. PMID:35095596
Gene Network of Susceptibility to Atypical Femoral Fractures Related to Bisphosphonate Treatment. PMID:35052486
Identification of prognostic biomarkers in papillary renal cell carcinoma and PTTG1 may serve as a biomarker for predicting immunotherapy response. PMID:35037540
Screening and Identification of Key Biomarkers in Lower Grade Glioma via Bioinformatical Analysis. PMID:35035531
Identification of Potential Biomarkers of Depression and Network Pharmacology Approach to Investigate the Mechanism of Key Genes and Therapeutic Traditional Chinese Medicine in the Treatment of Depression. PMID:35003290
Salivary and Intestinal Transcriptomes Reveal Differential Gene Expression in Starving, Fed and Trypanosoma cruzi-Infected Rhodnius neglectus. PMID:34988032
Integrated weighted gene coexpression network analysis identifies Frizzled 2 (FZD2) as a key gene in invasive malignant pleomorphic adenoma. PMID:34986855
Large-scale protein-protein post-translational modification extraction with distant supervision and confidence calibrated BioBERT. PMID:34983371
Canine transmissible venereal tumour established in immunodeficient mice reprograms the gene expression profiles associated with a favourable tumour microenvironment to enable cancer malignancy. PMID:34980125
Analysis of Microarray Data from Medulloblastoma Tissue Samples. PMID:34978688
The diagnostic and prognostic significance of small nuclear ribonucleoprotein Sm D1 aberrantly high expression in hepatocellular carcinoma. PMID:34976182
A Pilot Study on Early-Onset Schizophrenia Reveals the Implication of Wnt, Cadherin and Cholecystokinin Receptor Signaling in Its Pathophysiology. PMID:34976023
Screening and Identification of Muscle-Specific Candidate Genes via Mouse Microarray Data Analysis. PMID:34966817
Integrated Gene Expression Profiling Analysis Reveals Potential Molecular Mechanisms and Candidate Biomarkers for Early Risk Stratification and Prediction of STEMI and Post-STEMI Heart Failure Patients. PMID:34957234
A Novel Four-Gene Signature as a Potential Prognostic Biomarker for Hepatocellular Carcinoma. PMID:34950206
High Expression of BCL11A Predicts Poor Prognosis for Childhood MLL-r ALL. PMID:34938655
Establishment of Sunitinib-Resistant Xenograft Model of Renal Cell Carcinoma and the Identification of Drug-Resistant Hub Genes and Pathways. PMID:34938069
Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology. PMID:34932275
R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability. PMID:34916496
Identification and Validation of an 6-Metabolism-Related Gene Signature and Its Correlation With Immune Checkpoint in Hepatocellular Carcinoma. PMID:34869039
AURKB as a Promising Prognostic Biomarker in Hepatocellular Carcinoma. PMID:34866894
Inhibitor tolerance and bioethanol fermentability of levoglucosan-utilizing Escherichia coli were enhanced by overexpression of stress-responsive gene ycfR: The proteomics-guided metabolic engineering. PMID:34853817
Atg5 Regulates Selective Autophagy of the Parental Macronucleus during Tetrahymena Sexual Reproduction. PMID:34831293
Identification of Immunological Biomarkers of Atopic Dermatitis by Integrated Analysis to Determine Molecular Targets for Diagnosis and Therapy. PMID:34815693
Plasmin Cascade Mediates Thrombotic Events in SARS-CoV-2 Infection via Complement and Platelet-Activating Systems. PMID:34786557
Network based analysis identifies TP53m-BRCA1/2wt-homologous recombination proficient (HRP) population with enhanced susceptibility to Vigil immunotherapy. PMID:34785763
Identification of KIF4A as a prognostic biomarker for esophageal squamous cell carcinoma. PMID:34775374
Transcriptomic analysis reveals that coxsackievirus B3 Woodruff and GD strains use similar key genes to induce FoxO signaling pathway activation in HeLa cells. PMID:34773511
Putative Biomarkers for Acute Pulmonary Embolism in Exhaled Breath Condensate. PMID:34768685
Integrative Bioinformatics approaches to therapeutic gene target selection in various cancers for Nitroglycerin. PMID:34764329
Circulating miRNAs as Potential Biomarkers in Prostate Cancer Patients Undergoing Radiotherapy. PMID:34754245
Ploidy and recombination proficiency shape the evolutionary adaptation to constitutive DNA replication stress. PMID:34752451
Identification of C3 and FN1 as potential biomarkers associated with progression and prognosis for clear cell renal cell carcinoma. PMID:34688260
Staphylococcusaureus Transcriptome Data and Metabolic Modelling Investigate the Interplay of Ser/Thr Kinase PknB, Its Phosphatase Stp, the glmR/yvcK Regulon and the cdaA Operon for Metabolic Adaptation. PMID:34683468
Cell Wall Proteomics Reveal Phenotypic Adaption of Drug-Resistant Mycobacterium smegmatis to Subinhibitory Rifampicin Exposure. PMID:34676224
Analysis of Communal Molecular Mechanism and Potential Therapeutic Targets in Heart Failure and Type 2 Diabetes Mellitus. PMID:34675622
Huanglianjiedu Decoction as an effective treatment for oral squamous cell carcinoma based on network pharmacology and experimental validation. PMID:34674717
GNG7 and ADCY1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma through bioinformatic-based analyses. PMID:34650124
Arabidopsis LSH8 Positively Regulates ABA Signaling by Changing the Expression Pattern of ABA-Responsive Proteins. PMID:34638657
Proteomics: Concepts and applications in human medicine. PMID:34630910
Systematic Construction and Validation of an RNA-Binding Protein-Associated Prognostic Model for Acute Myeloid Leukemia. PMID:34630514
Exploring the mechanism of Jianpi Qushi Huayu Formula in the treatment of chronic glomerulonephritis based on network pharmacology. PMID:34618179
Exploring the Potential Mechanism of Shennao Fuyuan Tang for Ischemic Stroke Based on Network Pharmacology and Molecular Docking. PMID:34603472
The Identification of Gene Expression Profiles Associated with Granulomatous Mastitis. PMID:34602937
The Interactions of Small Proline-Rich Proteins with Late Cornified Envelope Proteins are Involved in the Pathogenesis of Psoriasis. PMID:34594126
Insilco identification and characterization of superoxide dismutase gene family in Brassica rapa. PMID:34588862
BCG immunotherapy inhibits cancer progression by promoting the M1 macrophage differentiation of THP‑1 cells via the Rb/E2F1 pathway in cervical carcinoma. PMID:34581419
Cyclic Hypoxia Conditioning Alters the Content of Myoblast-Derived Extracellular Vesicles and Enhances Their Cell-Protective Functions. PMID:34572398
Expression and prognosis of CDC45 in cervical cancer based on the GEO database. PMID:34557356
Association between chronic periodontitis and the risk of Alzheimer's disease: combination of text mining and GEO dataset. PMID:34556089
Prenylcysteine oxidase 1, an emerging player in atherosclerosis. PMID:34548610
Integrative analysis of hub genes and key pathway in two subtypes of diffuse large B-cell lymphoma by bioinformatics and basic experiments. PMID:34545634
Role of competitive endogenous RNA networks in the pathogenesis of coronary artery disease. PMID:34532371
Gene Expression Profiling of Contralateral Dorsal Root Ganglia Associated with Mirror-Image Pain in a Rat Model of Complex Regional Pain Syndrome Type-I. PMID:34512013
CT-detected extramural venous invasion-related gene signature for the overall survival prediction in patients with gastric cancer. PMID:34510798
Delineating chromatin accessibility re-patterning at single cell level during early stage of direct cardiac reprogramming. PMID:34509499
The 'un-shrunk' partial correlation in Gaussian graphical models. PMID:34493207
Integrative Analysis of Minichromosome Maintenance Proteins and Their Prognostic Significance in Melanoma. PMID:34490114
Discovery of Novel Biomarkers for Diagnosing and Predicting the Progression of Multiple Sclerosis Using TMT-Based Quantitative Proteomics. PMID:34489947
Mapping Transcriptome Data to Protein-Protein Interaction Networks of Inflammatory Bowel Diseases Reveals Disease-Specific Subnetworks. PMID:34484291
GSK2126458 has the potential to inhibit the proliferation of pancreatic cancer uncovered by bioinformatics analysis and pharmacological experiments. PMID:34461940
Discovery of Novel Host Molecular Factors Underlying HBV/HCV Infection. PMID:34458256
Uncovering cancer vulnerabilities by machine learning prediction of synthetic lethality. PMID:34454516
Deoxynivalenol and Zearalenone: Different Mycotoxins with Different Toxic Effects in the Sertoli Cells of Equus asinus. PMID:34440667
Phosphoproteomics Identifies Significant Biomarkers Associated with the Proliferation and Metastasis of Prostate Cancer. PMID:34437425
Network pharmacology-based prediction of the active compounds and mechanism of Buyang Huanwu Decoction for ischemic stroke. PMID:34434264
Dynamic bi-directional phosphorylation events associated with the reciprocal regulation of synapses during homeostatic up- and down-scaling. PMID:34433048
Identification of key genes and crucial pathways for major depressive disorder using peripheral blood samples and chronic unpredictable mild stress rat models. PMID:34414022
Investigation of Potential Molecular Biomarkers for Diagnosis and Prognosis of AFP-Negative HCC. PMID:34408477
Deciphering the Therapeutic Mechanisms of Wuzi Ershen Decoction in Treating Oligoasthenozoospermia through the Network Pharmacology Approach. PMID:34394386
Quantitative Peptidomics of Mouse Brain After Infection With Cyst-Forming Toxoplasma gondii. PMID:34367142
Comprehensive investigation of RNA-sequencing dataset reveals the hub genes and molecular mechanisms of coronavirus disease 2019 acute respiratory distress syndrome. PMID:34350693
High-Density Blood Transcriptomics Reveals Precision Immune Signatures of SARS-CoV-2 Infection in Hospitalized Individuals. PMID:34335605
Ovine CD14- an Immune Response Gene Has a Role Against Gastrointestinal Nematode Haemonchus contortus-A Novel Report. PMID:34335567
High Expression Levels of CDK1 and CDC20 in Patients With Lung Squamous Cell Carcinoma are Associated With Worse Prognosis. PMID:34307447
Analysis of DNA Methylation Profiles in Mandibular Condyle of Chicks With Crossed Beaks Using Whole-Genome Bisulfite Sequencing. PMID:34306022
Analysis of Hub Genes and the Mechanism of Immune Infiltration in Stanford Type a Aortic Dissection. PMID:34277731
Prognostic significance and oncogene function of cathepsin A in hepatocellular carcinoma. PMID:34272452
Molecular mechanisms of growth depression in broiler chickens (Gallus Gallus domesticus) mediated by immune stress: a hepatic proteome study. PMID:34253261
Bioinformatics analysis of the role of CXC ligands in the microenvironment of head and neck tumor. PMID:34247149
Integrative analysis of key candidate genes and signaling pathways in acute coronary syndrome related to obstructive sleep apnea by bioinformatics. PMID:34239024
Databases for Protein-Protein Interactions. PMID:34236665
Identification of endometriosis-associated genes and pathways based on bioinformatic analysis. PMID:34232189
Applications and analytical tools of cell communication based on ligand-receptor interactions at single cell level. PMID:34217372
Nanopore-based full-length transcriptome sequencing of Muscovy duck (Cairina moschata) ovary. PMID:34198095
Actualities in immunological markers and electrochemical sensors for determination of dopamine and its metabolites in psychotic disorders (Review). PMID:34194566
Genome-wide identification, phylogenetic, and expression analysis under abiotic stress conditions of LIM gene family in Medicago sativa L. PMID:34191816
A predictive biomarker panel for bone metastases: Liquid biopsy approach. PMID:34189028
ACSNI: An unsupervised machine-learning tool for prediction of tissue-specific pathway components using gene expression profiles. PMID:34179848
Topological Analysis of Regulatory Networks Reveals Functionally Key Genes and miRNAs Involved in the Differentiation of Mesenchymal Stem Cells. PMID:34179189
Low Expression of ADCY4 Predicts Worse Survival of Lung Squamous Cell Carcinoma Based on Integrated Analysis and Immunohistochemical Verification. PMID:34178627
Ultrasensitive single-cell proteomics workflow identifies >1000 protein groups per mammalian cell. PMID:34163866
Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma. PMID:34163522
Identification of Independent and Communal Differentially Expressed Genes as Well as Potential Therapeutic Targets in Ischemic Heart Failure and Non-Ischemic Heart Failure. PMID:34163213
Node Similarity Based Graph Convolution for Link Prediction in Biological Networks. PMID:34152393
Mapping the multiscale structure of biological systems. PMID:34139169
TIMEOR: a web-based tool to uncover temporal regulatory mechanisms from multi-omics data. PMID:34125906
Investigation of the Mechanism of Complement System in Diabetic Nephropathy via Bioinformatics Analysis. PMID:34124269
Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis. PMID:34122426
Identification of Disease-Specific Hub Biomarkers and Immune Infiltration in Osteoarthritis and Rheumatoid Arthritis Synovial Tissues by Bioinformatics Analysis. PMID:34113405
A new molecular classification to drive precision treatment strategies in primary Sjögren's syndrome. PMID:34112769
Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance. PMID:34099682
Surfactin, a quorum sensing signal molecule, globally affects the carbon metabolism in Bacillus amyloliquefaciens. PMID:34094854
Galectin-9 and PSMB8 overexpression predict unfavorable prognosis in patients with AML. PMID:34093826
ITRAQ-based quantitative proteomics reveals the proteome profiles of MDBK cells infected with bovine viral diarrhea virus. PMID:34092256
TMT-based quantitative proteomics analysis reveals the key proteins related with the differentiation process of goat intramuscular adipocytes. PMID:34090334
Transcriptional Response in the Digestive Gland of the King Scallop (Pecten maximus) After the Injection of Domoic Acid. PMID:34067146
Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons. PMID:34056454
Quantitative Proteomics Analysis of FFPE Tumor Samples Reveals the Influences of NET-1 siRNA Nanoparticles and Sonodynamic Therapy on Tetraspanin Protein Involved in HCC. PMID:34041269
The important role of MDM2, RPL5, and TP53 in mycophenolic acid-induced cleft lip and palate. PMID:34032749
Identification of key transcriptome biomarkers based on a vital gene module associated with pathological changes in Alzheimer's disease. PMID:34031265
The epigenetic regulator G9a attenuates stress-induced resistance and metabolic transcriptional programs across different stressors and species. PMID:34030685
Chaperonin-Containing TCP1 Subunit 6A Is a Prognostic Potential Biomarker That Correlates With the Presence of Immune Infiltrates in Colorectal Cancer. PMID:34017352
An overview of graph databases and their applications in the biomedical domain. PMID:34003247
Necrotic enteritis challenge regulates peroxisome proliferator-1 activated receptors signaling and β-oxidation pathways in broiler chickens. PMID:33997353
SOX4 as biomarker in hepatitis B virus-associated hepatocellular carcinoma. PMID:33995626
Genomic Analysis of Glioblastoma Multiforme Reveals a Key Transcription Factor Signature Relevant to Prognosis and the Immune Processes. PMID:33987093
Low expression of CHRDL1 and SPARCL1 predicts poor prognosis of lung adenocarcinoma based on comprehensive analysis and immunohistochemical validation. PMID:33980221
Screening and identification of LMNB1 and DLGAP5, two key biomarkers in gliomas. PMID:33956061
Active-Ingredient Screening and Synergistic Action Mechanism of Shegan Mixture for Anti-Asthma Effects Based on Network Pharmacology in a Mouse Model of Asthma. PMID:33953545
Analysis of key genes and related transcription factors in liver fibrosis based on bioinformatic technology. PMID:33936366
Neuromuscular junction-specific genes screening by deep RNA-seq analysis. PMID:33933147
GEE-TGDR: A Longitudinal Feature Selection Algorithm and Its Application to lncRNA Expression Profiles for Psoriasis Patients Treated with Immune Therapies. PMID:33928163
Metabolic, Organoleptic and Transcriptomic Impact of Saccharomyces cerevisiae Genes Involved in the Biosynthesis of Linear and Substituted Esters. PMID:33919724
Proteomic and Transcriptomic Analyses Reveal Pathological Changes in the Entorhinal Cortex Region that Correlate Well with Dysregulation of Ion Transport in Patients with Alzheimer's Disease. PMID:33904022
Multi-omics integration strategies for animal epigenetic studies - A review. PMID:33902167
Prognostic biomarkers and therapeutic targets in oral squamous cell carcinoma: a study based on cross-database analysis. PMID:33892811
CDC20 and PTTG1 are Important Biomarkers and Potential Therapeutic Targets for Metastatic Prostate Cancer. PMID:33881746
An ensemble of the iCluster method to analyze longitudinal lncRNA expression data for psoriasis patients. PMID:33879268
Identification of a Gene Prognostic Signature for Oral Squamous Cell Carcinoma by RNA Sequencing and Bioinformatics. PMID:33869632
Integrated Genomic and Transcriptomic Analysis reveals key genes for predicting dual-phenotype Hepatocellular Carcinoma Prognosis. PMID:33854600
Profiles of alternative splicing events in the diagnosis and prognosis of Gastric Cancer. PMID:33854599
Balancing precision versus cohort transcriptomic analysis of acute and recovery phase of viral bronchiolitis. PMID:33851876
A long non-coding RNAs expression signature to improve prognostic prediction of Wilms tumor in children. PMID:33850811
Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways. PMID:33846781
Multi-omics reveals novel prognostic implication of SRC protein expression in bladder cancer and its correlation with immunotherapy response. PMID:33830879
Identification of a Six Gene Prognosis Signature for Papillary Thyroid Cancer Using Multi-Omics Methods and Bioinformatics Analysis. PMID:33816258
COL5A2 Promotes Proliferation and Invasion in Prostate Cancer and Is One of Seven Gleason-Related Genes That Predict Recurrence-Free Survival. PMID:33816226
In Silico Analysis of Huntingtin Homologs in Lower Eukaryotes. PMID:33809947
The Effect of Infertility on the Liver Structure, Endocrinology, and Gene Network in Japanese Flounder. PMID:33806167
Emerging Role of ODC1 in Neurodevelopmental Disorders and Brain Development. PMID:33806076
Identification of Hub Genes and Key Pathways Associated with Anti-VEGF Resistant Glioblastoma Using Gene Expression Data Analysis. PMID:33803224
Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development. PMID:33797837
Immune Interaction Map of Human SARS-CoV-2 Target Genes: Implications for Therapeutic Avenues. PMID:33796097
Identification of a Novel Four-Gene Signature Correlated With the Prognosis of Patients With Hepatocellular Carcinoma: A Comprehensive Analysis. PMID:33777771
Activation of Toll-Like Receptor 7 Signaling Pathway in Primary Sjögren's Syndrome-Associated Thrombocytopenia. PMID:33767707
Identification of pivotal genes associated with the prognosis of gastric carcinoma through integrated analysis. PMID:33754626
Prognostic Risk Model of Immune-Related Genes in Colorectal Cancer. PMID:33747044
Integrating 3D structural information into systems biology. PMID:33744294
Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of Buyang Huanwu Decoction in the Treatment of Ischemic Stroke. PMID:33727944
Genome-wide transcriptome profiling uncovers differential miRNAs and lncRNAs in ovaries of Hu sheep at different developmental stages. PMID:33712687
Magnetic Field Induced Changes in the Shoot and Root Proteome of Barley (Hordeum vulgare L.). PMID:33708230
A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models. PMID:33705438
Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer. PMID:33682294
Protein domain identification methods and online resources. PMID:33680357
FAST1 Predicts Poor Survival of Renal Carcinoma and Promotes Its Progression Through the TGF-β/Smad Pathway. PMID:33679133
Study on the transcriptome for breast muscle of chickens and the function of key gene RAC2 on fibroblasts proliferation. PMID:33676413
Integrated genomic analysis reveals regulatory pathways and dynamic landscapes of the tRNA transcriptome. PMID:33664286
Network pharmacology and RNA-sequencing reveal the molecular mechanism of Xuebijing injection on COVID-19-induced cardiac dysfunction. PMID:33662681
Integrated RNA Sequencing Reveals Epigenetic Impacts of Diesel Particulate Matter Exposure in Human Cerebral Organoids. PMID:33657557
MMP7 as a potential biomarker of colon cancer and its prognostic value by bioinformatics analysis. PMID:33655961
Computational screening of potential glioma-related genes and drugs based on analysis of GEO dataset and text mining. PMID:33635875
Construction of a robust prognostic model for adult adrenocortical carcinoma: Results from bioinformatics and real-world data. PMID:33626208
Direct cell reprogramming: approaches, mechanisms and progress. PMID:33619373
Identification of Hub Genes and Immune Infiltration in Psoriasis by Bioinformatics Method. PMID:33613635
RNAi activation with homologous and heterologous sequences that induce resistance against the begomovirus Pepper golden mosaic virus (PepGMV). PMID:33604230
Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential mechanisms mediating neuroinflammation and pain. PMID:33602238
HBB mutations and HbA2 level: Escaping the carrier screening programs. PMID:33598281
Study on cocoonase, sericin, and degumming of silk cocoon: computational and experimental. PMID:33594479
Screening and identification of hub genes in bladder cancer by bioinformatics analysis and KIF11 is a potential prognostic biomarker. PMID:33574944
Blocking the short isoform of augmenter of liver regeneration inhibits proliferation of human multiple myeloma U266 cells via the MAPK/STAT3/cell cycle signaling pathway. PMID:33574936
Microarray Data Mining and Preliminary Bioinformatics Analysis of Hepatitis D Virus-Associated Hepatocellular Carcinoma. PMID:33564675
KinPred: A unified and sustainable approach for harnessing proteome-level human kinase-substrate predictions. PMID:33556051
Inhibitory effect of sodium butyrate on colorectal cancer cells and construction of the related molecular network. PMID:33549042
The extracellular matrix phenome across species. PMID:33543035
A Novel mRNA-miRNA Regulatory Sub-Network Associated With Prognosis of Metastatic Clear Cell Renal Cell Carcinoma. PMID:33542901
ENAM gene associated with T classification and inhibits proliferation in renal clear cell carcinoma. PMID:33539322
Tumor microenvironment characterization in triple-negative breast cancer identifies prognostic gene signature. PMID:33536349
An edge-based statistical analysis of long non-coding RNA expression profiles reveals a negative association between Parkinson's disease and colon cancer. PMID:33531021
High expression of MAPK-14 promoting the death of chondrocytes is an important signal of osteoarthritis process. PMID:33520453
Nras Q61R/+ and Kras-/- cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors. PMID:33512434
Exploring the mechanism of aidi injection for lung cancer by network pharmacology approach and molecular docking validation. PMID:33506873
A proteome signature for acute incisional pain in dorsal root ganglia of mice. PMID:33492035
COL1A1 Is a Potential Prognostic Biomarker and Correlated with Immune Infiltration in Mesothelioma. PMID:33490271
NLPEI: A Novel Self-Interacting Protein Prediction Model Based on Natural Language Processing and Evolutionary Information. PMID:33488064
Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival. PMID:33483501
Identification of Potential Risk Genes and the Immune Landscape of Idiopathic Pulmonary Arterial Hypertension via Microarray Gene Expression Dataset Reanalysis. PMID:33478117
Identifying FBLN1 (Gene ID: 2192) as a Potential Melanoma Biomarker for Melanoma based on an Analysis of microRNA Expression Profiles in the GEO and TCGA Databases. PMID:33470885
CHRNA5 belongs to the secondary estrogen signaling network exhibiting prognostic significance in breast cancer. PMID:33469842
Multiplexed MRM-Based Proteomics Identified Multiple Biomarkers of Disease Severity in Human Heart Failure. PMID:33467687
Serum lipocalin-2 is a potential biomarker for the clinical diagnosis of nonalcoholic steatohepatitis. PMID:33465844
The expression and prognostic value of GLYATL1 and its potential role in hepatocellular carcinoma. PMID:33457003
Transcript levels of keratin 1/5/6/14/15/16/17 as potential prognostic indicators in melanoma patients. PMID:33441834
Drug repurposing for opioid use disorders: integration of computational prediction, clinical corroboration, and mechanism of action analyses. PMID:33432189
Comprehensive assessments of germline deletion structural variants reveal the association between prognostic MUC4 and CEP72 deletions and immune response gene expression in colorectal cancer patients. PMID:33431054
Screening druggable targets and predicting therapeutic drugs for COVID-19 via integrated bioinformatics analysis. PMID:33428154
miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells. PMID:33425897
Relevance of STK11 Mutations Regarding Immune Cell Infiltration, Drug Sensitivity, and Cellular Processes in Lung Adenocarcinoma. PMID:33425731
Chromatin phosphoproteomics unravels a function for AT-hook motif nuclear localized protein AHL13 in PAMP-triggered immunity. PMID:33419940
Systematic Analysis of the Expression and Prognostic Significance of P4HA1 in Pancreatic Cancer and Construction of a lncRNA-miRNA-P4HA1 Regulatory Axis. PMID:33415167
Sex-dependent differences in the secretome of human endothelial cells. PMID:33413676
The histone methyltransferase inhibitor A-366 enhances hemoglobin expression in erythroleukemia cells upon co-exposure with chemical inducers in culture. PMID:33407944
Identification of predictors based on drug targets highlights accurate treatment of goserelin in breast and prostate cancer. PMID:33407865
Analysis of N6-Methyladenosine Methyltransferase Reveals METTL14 and ZC3H13 as Tumor Suppressor Genes in Breast Cancer. PMID:33363011
Developmental programming: Adipose depot-specific transcriptional regulation by prenatal testosterone excess in a sheep model of PCOS. PMID:33359827
Identification of key genes and pathways in endometriosis by integrated expression profiles analysis. PMID:33354413
MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced obese mice. PMID:33349332
Identify and Validate the Transcriptomic, Functional Network, and Predictive Validity of FBXL19-AS1 in Hepatocellular Carcinoma. PMID:33344260
Hypoxia-Associated Prognostic Markers and Competing Endogenous RNA Co-Expression Networks in Breast Cancer. PMID:33344235
Transcriptome Analysis Illuminates a Hub Role of SREBP2 in Cholesterol Metabolism by α-Mangostin. PMID:33324821
Postnatal Growth Restriction in Mice Alters Cardiac Protein Composition and Leads to Functional Impairment in Adulthood. PMID:33322681
Identification of potential oxidative stress biomarkers for spinal cord injury in erythrocytes using mass spectrometry. PMID:33318408
Identification of long non-coding RNA signatures for squamous cell carcinomas and adenocarcinomas. PMID:33318305
Convergent network effects along the axis of gene expression during prostate cancer progression. PMID:33317623
Plasma Proteome Profiling of Coronary Artery Disease Patients: Downregulation of Transthyretin-An Important Event. PMID:33299376
Germline variation networks in the PI3K/AKT pathway corresponding to familial high-incidence lung cancer pedigrees. PMID:33297998
Screening and Identification of Differentially Expressed and Adipose Growth-Related Protein-Coding Genes During the Deposition of Perirenal Adipose Tissue in Rabbits. PMID:33293841
SPOCK1/SIX1axis promotes breast cancer progression by activating AKT/mTOR signaling. PMID:33293473
The effect of a novel glycolysis-related gene signature on progression, prognosis and immune microenvironment of renal cell carcinoma. PMID:33287763
Differences in key genes in human alveolar macrophages between phenotypically normal smokers and nonsmokers: diagnostic and prognostic value in lung cancer. PMID:33284895
Identification of Monotonically Differentially Expressed Genes across Pathologic Stages for Cancers. PMID:33273919
We need to keep a reproducible trace of facts, predictions, and hypotheses from gene to function in the era of big data. PMID:33253151
UBC9 coordinates inflammation affecting development of bladder cancer. PMID:33244139
Multiple functions of TBCK protein in neurodevelopment disorders and tumors. PMID:33240423
The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets. PMID:33237311
Use of bioinformatic analyses in identifying characteristic genes and mechanisms active in the progression of idiopathic thrombocytopenic purpura in individuals with different phenotypes. PMID:33222560
Colon cancer-specific diagnostic and prognostic biomarkers based on genome-wide abnormal DNA methylation. PMID:33202377
Identification of Prognostic Model and Biomarkers for Cancer Stem Cell Characteristics in Glioblastoma by Network Analysis of Multi-Omics Data and Stemness Indices. PMID:33195193
Electroacupuncture Alleviates Mechanical Allodynia of a Rat Model of CRPS-I and Modulates Gene Expression Profiles in Dorsal Root Ganglia. PMID:33193035
ID1 As a Prognostic Biomarker and Promising Drug Target Plays a Pivotal Role in Deterioration of Clear Cell Renal Cell Carcinoma. PMID:33178820
A methodology for predicting tissue-specific metabolic roles of receptors applied to subcutaneous adipose. PMID:33177567
CENPE, PRC1, TTK, and PLK4 May Play Crucial Roles in the Osteosarcoma Progression. PMID:33176597
Exploring the potential therapeutic effect of traditional Chinese medicine on coronavirus disease 2019 (COVID-19) through a combination of data mining and network pharmacology analysis. PMID:33163124
RNA-seq transcriptome analysis in flounder cells to compare innate immune responses to low- and high-virulence viral hemorrhagic septicemia virus. PMID:33145636
Isobaric Tagging for Relative and Absolute Protein Quantification (iTRAQ)-Based Quantitative Proteomics Analysis of Differentially Expressed Proteins 1 Week After Spinal Cord Injury in a Rat Model. PMID:33144554
A holistic view of mouse enhancer architectures reveals analogous pleiotropic effects and correlation with human disease. PMID:33138777
Changes in Honey Bee Head Proteome in Response to Dietary 24-Methylenecholesterol. PMID:33138161
High Expression of UBB, RAC1, and ITGB1 Predicts Worse Prognosis among Nonsmoking Patients with Lung Adenocarcinoma through Bioinformatics Analysis. PMID:33134373
Stromal microenvironment promoted infiltration in esophageal adenocarcinoma and squamous cell carcinoma: a multi-cohort gene-based analysis. PMID:33122682
Identification of a Twelve-Gene Signature and Establishment of a Prognostic Nomogram Predicting Overall Survival for Medulloblastoma. PMID:33101383
Identification of key genes and novel immune infiltration-associated biomarkers of sepsis. PMID:33100122
RobNorm: model-based robust normalization method for labeled quantitative mass spectrometry proteomics data. PMID:33098413
Lineage-Specific Proteomic Signatures in the Mycobacterium tuberculosis Complex Reveal Differential Abundance of Proteins Involved in Virulence, DNA Repair, CRISPR-Cas, Bioenergetics and Lipid Metabolism. PMID:33072011
The role of RBM10 mutations in the development, treatment, and prognosis of lung adenocarcinoma. PMID:33064970
Genes regulating membrane-associated E-cadherin and proliferation in adenomatous polyposis coli mutant colon cancer cells: High content siRNA screen. PMID:33057364
Bioinformatic gene analysis for potential therapeutic targets of Huntington's disease in pre-symptomatic and symptomatic stage. PMID:33054835
Environmental Epigenetics of Diesel Particulate Matter Toxicogenomics. PMID:33050454
Suppression of the TGF-β pathway by a macrolide antibiotic decreases fibrotic responses by ocular fibroblasts in vitro. PMID:33047019
Transcriptome-Based Network Analysis Unveils Eight Immune-Related Genes as Molecular Signatures in the Immunomodulatory Subtype of Triple-Negative Breast Cancer. PMID:33042828
Extensive fragmentation and re-organization of transcription in Systemic Lupus Erythematosus. PMID:33024230
Survival Strategies of Pathogenic Candida Species in Human Blood Show Independent and Specific Adaptations. PMID:33024045
Integrin Beta 1 Promotes Glioma Cell Proliferation by Negatively Regulating the Notch Pathway. PMID:33014056
Summary-data-based Mendelian randomization prioritizes potential druggable targets for multiple sclerosis. PMID:33005893
Development of an Immune-Related Risk Signature for Predicting Prognosis in Lung Squamous Cell Carcinoma. PMID:33005178
Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: A model for studying atherogenic mechanisms. PMID:33002093
Identification of Potential Biomarkers and Related Transcription Factors in Peripheral Blood of Tuberculosis Patients. PMID:32987825
Transcriptome analysis based on RNA-seq of common innate immune responses of flounder cells to IHNV, VHSV, and HIRRV. PMID:32986779
Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease. PMID:32985496
Transcriptomic Analysis Revealed an Emerging Role of Alternative Splicing in Embryonal Tumor with Multilayered Rosettes. PMID:32971786
Genetic factors related to the widespread dissemination of ST11 extensively drug-resistant carbapenemase-producing Klebsiella pneumoniae strains within hospital. PMID:32969865
γ-Aminobutyric Acid Enhances Heat Tolerance Associated with the Change of Proteomic Profiling in Creeping Bentgrass. PMID:32961841
Identification of hub genes in diabetic kidney disease via multiple-microarray analysis. PMID:32953797
Identification, Validation, and Functional Annotations of Genome-Wide Profile Variation between Melanocytic Nevus and Malignant Melanoma. PMID:32934956
Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses. PMID:32929263
Identification of tumor-infiltrating immune cells and prognostic validation of tumor-infiltrating mast cells in adrenocortical carcinoma: results from bioinformatics and real-world data. PMID:32923148
ANDDigest: a new web-based module of ANDSystem for the search of knowledge in the scientific literature. PMID:32921303
A Quantitative Proteome Map of the Human Body. PMID:32916130
Identification and validation of novel metastasis-related signatures of clear cell renal cell carcinoma using gene expression databases. PMID:32913492
Identification of Biomarkers to Construct a Competing Endogenous RNA Network and Establishment of a Genomic-Clinicopathologic Nomogram to Predict Survival for Children with Rhabdoid Tumors of the Kidney. PMID:32908900
Bioinformatic analysis reveals hub genes and pathways that promote melanoma metastasis. PMID:32894090
Combined proteomics and transcriptomics reveal the genetic basis underlying the differentiation of skin appendages and immunity in pangolin. PMID:32884035
Genome-wide pathogenesis interpretation using a heat diffusion-based systems genetics method and implications for gene function annotation. PMID:32869547
Comprehensive study of altered proteomic landscape in proximal renal tubular epithelial cells in response to calcium oxalate monohydrate crystals. PMID:32867742
Comprehensive analysis of key genes associated with ceRNA networks in nasopharyngeal carcinoma based on bioinformatics analysis. PMID:32863767
Diurnal Differences in Human Muscle Isometric Force In Vivo Are Associated with Differential Phosphorylation of Sarcomeric M-Band Proteins. PMID:32859009
Identification and Characterization of MAPK Signaling Pathway Genes and Associated lncRNAs in the Ileum of Piglets Infected by Clostridium perfringens Type C. PMID:32855971
Constructing cancer patient-specific and group-specific gene networks with multi-omics data. PMID:32854705
Mito-oncology agent: fermented extract suppresses the Warburg effect, restores oxidative mitochondrial activity, and inhibits in vivo tumor growth. PMID:32843660
Bioinformatic Profiling of Prognosis-Related Genes in Malignant Glioma Microenvironment. PMID:32843610
Identification of the Effects of Aspirin and Sulindac Sulfide on the Inhibition of HMGA2-Mediated Oncogenic Capacities in Colorectal Cancer. PMID:32842685
Six-Gene Signature Associated with Immune Cells in the Progression of Atherosclerosis Discovered by Comprehensive Bioinformatics Analyses. PMID:32821283
Identification of UBE2T as an independent prognostic biomarker for gallbladder cancer. PMID:32802166
Identification and Validation of Key Genes Associated With Systemic Sclerosis-Related Pulmonary Hypertension. PMID:32793290
Bioinformatics analysis shows that TOP2A functions as a key candidate gene in the progression of cervical cancer. PMID:32765860
Bioinformatic screening and identification of downregulated hub genes in adrenocortical carcinoma. PMID:32765768
Comprehensive Network Analysis Reveals Alternative Splicing-Related lncRNAs in Hepatocellular Carcinoma. PMID:32760422
Abnormal expression and prognostic significance of EPB41L1 in kidney renal clear cell carcinoma based on data mining. PMID:32760223
Prognostic implication and functional annotations of APOBEC3G expression in patients with Melanoma. PMID:32742470
Genomic, transcriptomic, and protein landscape profile of CFTR and cystic fibrosis. PMID:32734384
Identification of key genes in calcific aortic valve disease by integrated bioinformatics analysis. PMID:32702920
Identification of potential molecular mechanisms and small molecule drugs in myocardial ischemia/reperfusion injury. PMID:32696819
Complex-centric proteome profiling by SEC-SWATH-MS for the parallel detection of hundreds of protein complexes. PMID:32690956
Comparative study of gene expression profiles rooted in acute myocardial infarction and ischemic/reperfusion rat models. PMID:32685266
Understanding the genetics of systemic lupus erythematosus using Bayesian statistics and gene network analysis. PMID:32683804
MicroRNAs Regulated by the LPS/TLR2 Immune Axis as Bona Fide Biomarkers for Diagnosis of Acute Leptospirosis. PMID:32669469
Identification of candidate biomarkers and pathways associated with psoriasis using bioinformatics analysis. PMID:32669126
Characterization of ASR gene and its role in drought tolerance in chickpea (Cicer arietinum L.). PMID:32663226
TopicNet: a framework for measuring transcriptional regulatory network change. PMID:32657410
Quantitative Proteomics of Urinary Bladder Cancer Cell Lines Identify UAP1 as a Potential Therapeutic Target. PMID:32650368
Tomato contrasting genotypes responses under combined salinity and viral stresses. PMID:32647458
Mechanism of Astragalus membranaceus in the treatment of laryngeal cancer based on gene co-expression network and molecular docking. PMID:32636440
Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways. PMID:32634473
Screening and identification of key gene in sepsis development: Evidence from bioinformatics analysis. PMID:32629654
Identification of differentially expressed mRNA and the Hub mRNAs modulated by lncRNA Meg3 as a competing endogenous RNA in brown adipose tissue of mice on a high-fat diet. PMID:32614631
Comprehensive Analysis of a Long Noncoding RNA-Associated Competing Endogenous RNA Network in Wilms Tumor. PMID:32597194
Identification of hydatidosis-related modules and key regulatory genes. PMID:32596042
A Comprehensive Network Pharmacology-Based Strategy to Investigate Multiple Mechanisms of HeChan Tablet on Lung Cancer. PMID:32595734
Hub genes and key pathways of traumatic brain injury: bioinformatics analysis and in vivo validation. PMID:32594047
Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1. PMID:32574189
Adaptive Molecular Evolution of AKT3 Gene for Positive Diversifying Selection in Mammals. PMID:32550227
Immune profiling reveals prognostic genes in high-grade serous ovarian cancer. PMID:32544083
Pseudomonas aeruginosa N-3-Oxo-Dodecanoyl-Homoserine Lactone Impacts Mitochondrial Networks Morphology, Energetics, and Proteome in Host Cells. PMID:32523583
Proteomic analysis of human synovial fluid reveals potential diagnostic biomarkers for ankylosing spondylitis. PMID:32518534
Developmental Programming: Sheep Granulosa and Theca Cell-Specific Transcriptional Regulation by Prenatal Testosterone. PMID:32516392
Gene-environment interaction: New insights into perceived parenting and social anxiety among adolescents. PMID:32507125
Whole exome sequencing of a Saudi family and systems biology analysis identifies CPED1 as a putative causative gene to Celiac Disease. PMID:32489286
Master Sculptor at Work: Enteropathogenic Escherichia coli Infection Uniquely Modifies Mitochondrial Proteolysis during Its Control of Human Cell Death. PMID:32487743
Genome-Wide Characterization of GRAS Family and Their Potential Roles in Cold Tolerance of Cucumber (Cucumis sativus L.). PMID:32485801
Scoring functions for drug-effect similarity. PMID:32484516
Functional Annotations of Single-Nucleotide Polymorphism (SNP)-Based and Gene-Based Genome-Wide Association Studies Show Genes Affecting Keratitis Susceptibility. PMID:32450567
Expression profiling of spinal cord dorsal horn in a rat model of complex regional pain syndrome type-I uncovers potential mechanisms mediating pain and neuroinflammation responses. PMID:32446302
Screening and identification of key biomarkers for retinoblastoma: Evidence from bioinformatics analysis. PMID:32443297
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans. PMID:32438927
Circulating MicroRNAs Regulating DNA Damage Response and Responsiveness to Cisplatin in the Prognosis of Patients with Non-Small Cell Lung Cancer Treated with First-Line Platinum Chemotherapy. PMID:32438598
ThETA: transcriptome-driven efficacy estimates for gene-based TArget discovery. PMID:32437556
Transcriptome profiling of digital flexor tendons after injury in a chicken model. PMID:32432656
Arginine Deiminase and Biotin Metabolism Signaling Pathways Play an Important Role in Human-Derived Serotype V, ST1 Streptococcus agalactiae Virulent Strain upon Infected Tilapia. PMID:32423070
Epigenome-Wide Tobacco-Related Methylation Signature Identification and Their Multilevel Regulatory Network Inference for Lung Adenocarcinoma. PMID:32420331
Key genes of renal tubular necrosis: a bioinformatics analysis. PMID:32420172
Developmental programming: Transcriptional regulation of visceral and subcutaneous adipose by prenatal bisphenol-A in female sheep. PMID:32417515
Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel. PMID:32413042
Identification of Key Players Involved in CoCl2 Hypoxia Induced Pulmonary Artery Hypertension in vitro. PMID:32391042
Altered protein levels in bone marrow lesions of hip osteoarthritis: Analysis by proteomics and multiplex immunoassays. PMID:32383346
Evaluation of the proteomic profiles of ejaculated spermatozoa from Saanen bucks ( Capra hircus ). PMID:32368270
Analysis of DNA methylation profiles during sheep skeletal muscle development using whole-genome bisulfite sequencing. PMID:32349667
Construction and analysis for differentially expressed long non-coding RNAs and mRNAs in acute myocardial infarction. PMID:32332808
Identification of hub genes and small-molecule compounds in medulloblastoma by integrated bioinformatic analyses. PMID:32328342
Identification of key candidate genes and pathways revealing the protective effect of liraglutide on diabetic cardiac muscle by integrated bioinformatics analysis. PMID:32309328
ZGRF1 Is Associated with Poor Prognosis in Triple-Negative Breast Cancer and Promotes Cancer Stemness Based on Bioinformatics. PMID:32308418
Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses. PMID:32295833
Modulation of stress and immune response by Amblyomin-X results in tumor cell death in a horse melanoma model. PMID:32286411
Down-regulated Solute Carrier Family 4 Member 4 Predicts Poor Progression in Colorectal Cancer. PMID:32284764
Contributions of Gene Modules Regulated by Essential Noncoding RNA in Colon Adenocarcinoma Progression. PMID:32280704
Network Systems Pharmacology-Based Mechanism Study on the Beneficial Effects of Vitamin D against Psychosis in Alzheimer's Disease. PMID:32273551
Identification of core genes associated with prostate cancer progression and outcome via bioinformatics analysis in multiple databases. PMID:32266115
Influenza-Induced Interferon Lambda Response Is Associated With Longer Time to Delivery Among Pregnant Kenyan Women. PMID:32256497
Genome-Wide Analysis Reveals Stress and Hormone Responsive Patterns of JAZ Family Genes in Camellia Sinensis. PMID:32244526
ProGeo-neo: a customized proteogenomic workflow for neoantigen prediction and selection. PMID:32241270
Compensation of Mutation in Arabidopsis glutathione transferase (AtGSTU) Genes under Control or Salt Stress Conditions. PMID:32231125
EphB2 represents an independent prognostic marker in patients with gastric cancer and promotes tumour cell aggressiveness. PMID:32226496
WeiBI (web-based platform): Enriching integrated interaction network with increased coverage and functional proteins from genome-wide experimental OMICS data. PMID:32221380
Validation of the Key Active Ingredients and Anti-Inflammatory and Analgesic Effects of Shenjin Huoxue Mixture Against Osteoarthritis by Integrating Network Pharmacology Approach and Thin-Layer Chromatography Analysis. PMID:32214800
Malignant Evaluation and Clinical Prognostic Values of m6A RNA Methylation Regulators in Glioblastoma. PMID:32211315
Feature selection based on differentially correlated gene pairs reveals the mechanism of IFN-β therapy for multiple sclerosis. PMID:32211244
Fatty acid-binding protein 5 predicts poor prognosis in patients with uveal melanoma. PMID:32194670
Gene Expression Alterations and Molecular Analysis of CHEK1 in Solid Tumors. PMID:32178478
Fast and Robust Proteome Screening Platform Identifies Neutrophil Extracellular Trap Formation in the Lung in Response to Cobalt Ferrite Nanoparticles. PMID:32167280
Comprehensive Analysis of lncRNA-Mediated ceRNA Crosstalk and Identification of Prognostic Biomarkers in Wilms' Tumor. PMID:32149111
Label-free quantitative identification of abnormally ubiquitinated proteins as useful biomarkers for human lung squamous cell carcinomas. PMID:32140187
CDK1 and CDC20 overexpression in patients with colorectal cancer are associated with poor prognosis: evidence from integrated bioinformatics analysis. PMID:32127012
Components of the endocytic and recycling trafficking pathways interfere with the integrity of the Legionella-containing vacuole. PMID:32096265
A Guide to Conquer the Biological Network Era Using Graph Theory. PMID:32083072
Tracking intratumoral heterogeneity in glioblastoma via regularized classification of single-cell RNA-Seq data. PMID:32070274
Machine Learning and Bioinformatics Models to Identify Pathways that Mediate Influences of Welding Fumes on Cancer Progression. PMID:32066756
Network Pharmacology-Based Prediction and Verification of Qingluo Tongbi Formula to Reduce Liver Toxicity of Tripterygium wilfordii via UGT2B7 in Endoplasmic Reticulum. PMID:32061080
Enhancing reproducibility of gene expression analysis with known protein functional relationships: The concept of well-associated protein. PMID:32058996
Deriving disease modules from the compressed transcriptional space embedded in a deep autoencoder. PMID:32051402
Identification of Urinary Biomarkers for Exercise-Induced Immunosuppression by iTRAQ Proteomics. PMID:32047808
Identification of AIDS-Associated Kaposi Sarcoma: A Functional Genomics Approach. PMID:32038721
Bioinformatics Analysis of Global Proteomic and Phosphoproteomic Data Sets Revealed Activation of NEK2 and AURKA in Cancers. PMID:32033228
Identifying Synergistic Mechanisms of Multiple Ingredients in Shuangbai Tablets against Proteinuria by Virtual Screening and a Network Pharmacology Approach. PMID:32025234
Protein sorting into protein bodies during barley endosperm development is putatively regulated by cytoskeleton members, MVBs and the HvSNF7s. PMID:32024857
Integrative analysis of highly mutated genes in hepatitis B virus-related hepatic carcinoma. PMID:32017470
Exploring the Key Genes and Pathways in the Formation of Corneal Scar Using Bioinformatics Analysis. PMID:32016117
Identification of genes of prognostic value in the ccRCC microenvironment from TCGA database. PMID:32012488
The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the transcriptome of aryl hydrocarbon receptor (AhR) knock-down porcine granulosa cells. PMID:32002328
Identification of Key Genes and Prognostic Analysis between Chromophobe Renal Cell Carcinoma and Renal Oncocytoma by Bioinformatic Analysis. PMID:31998788
Genome-wide identification and expression of GRAS gene family members in cassava. PMID:31996133
Identification of Key Biomarkers in Bladder Cancer: Evidence from a Bioinformatics Analysis. PMID:31991631
Tumor necrosis factor α promotes HEp-2 cell proliferation via toll-like receptor 4 and NF-κB signaling pathways. PMID:31966525
The proteome of IVF-induced aberrant embryo-maternal crosstalk by implantation stage in ewes. PMID:31956410
Cytochrome P450 family proteins as potential biomarkers for ovarian granulosa cell damage in mice with premature ovarian failure. PMID:31949819
Based on network pharmacology to explore the molecular mechanisms of astragalus membranaceus for treating T2 diabetes mellitus. PMID:31930034
Identification of Monotonically Differentially Expressed Genes for IFN-β-Treated Multiple Sclerosis Patients. PMID:31915697
Prognostic value of epithelial-mesenchymal transition markers in clear cell renal cell carcinoma. PMID:31915310
Identification of key candidate tumor biomarkers in non-small-cell lung cancer by in silico analysis. PMID:31897214
Enhancement of immune response against Bordetella spp. by disrupting immunomodulation. PMID:31889098
Identification of key genes and pathways in abdominal aortic aneurysm by integrated bioinformatics analysis. PMID:31885343
Investigating host-bacterial interactions among enteric pathogens. PMID:31881845
Gene Expression Profiles in Primary Sjögren's Syndrome With and Without Systemic Manifestations. PMID:31872181
Weighted gene expression profiles identify diagnostic and prognostic genes for lung adenocarcinoma and squamous cell carcinoma. PMID:31854219
Characterization of protein, long noncoding RNA and microRNA signatures in extracellular vesicles derived from resting and degranulated mast cells. PMID:31853339
Systematic expression analysis of WEE family kinases reveals the importance of PKMYT1 in breast carcinogenesis. PMID:31837068
Plasma membrane V-ATPase controls oncogenic RAS-induced macropinocytosis. PMID:31827278
The Role of Serine Peptidase Inhibitor Kazal Type 13 (SPINK13) as a Clinicopathological and Prognostic Biomarker in Patients with Clear Cell Renal Cell Carcinoma. PMID:31825950
Projection-Based Neighborhood Non-Negative Matrix Factorization for lncRNA-Protein Interaction Prediction. PMID:31824563
Screening Hub Genes as Prognostic Biomarkers of Hepatocellular Carcinoma by Bioinformatics Analysis. PMID:31822116
Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA-induced differentiation of leukemic cells. PMID:31820845
Integrated analysis of lncRNA CTD-2357A8.3 expression and its potential roles in head and neck squamous cell carcinoma. PMID:31807160
Species-specific transcriptional profiles of the gut and gut microbiome of Ceratitis quilicii and Ceratitis rosa sensu stricto. PMID:31798006
Identification of key candidate genes for colorectal cancer by bioinformatics analysis. PMID:31788116
Screening and characterization of long noncoding RNAs involved in the albinism of Ananas comosus var. bracteatus leaves. PMID:31756232
ENCORE: A Visualization Tool for Insight into Circadian Omics. PMID:31754663
Identification of prognostic genes in the acute myeloid leukemia microenvironment. PMID:31740623
Discovery of disease- and drug-specific pathways through community structures of a literature network. PMID:31738408
A Dynamic Transcriptional Analysis Reveals IL-6 Axis as a Prominent Mediator of Surgical Acute Response in Non-ischemic Mouse Heart. PMID:31736788
Identification of the molecular mechanisms associated with acute type A aortic dissection through bioinformatics methods. PMID:31721906
Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma. PMID:31703694
Transcriptome profiling analysis of sex-based differentially expressed mRNAs and lncRNAs in the brains of mature zebrafish (Danio rerio). PMID:31703616
Mitochondrial dysfunction in rheumatoid arthritis: A comprehensive analysis by integrating gene expression, protein-protein interactions and gene ontology data. PMID:31703070
Proteomics Profiling of Autologous Blood and Semen Exosomes from HIV-infected and Uninfected Individuals Reveals Compositional and Functional Variabilities. PMID:31676584
Gene expression profile analysis of ileum transcriptomes in pigs fed Gelsemium elegans plants. PMID:31673142
New insights into the heat responses of grape leaves via combined phosphoproteomic and acetylproteomic analyses. PMID:31666961
Potential biomarker identification for Friedreich's ataxia using overlapping gene expression patterns in patient cells and mouse dorsal root ganglion. PMID:31665133
Increased expression of TET3 predicts unfavorable prognosis in patients with ovarian cancer-a bioinformatics integrative analysis. PMID:31656201
Identification of key protein-coding genes and lncRNAs in spontaneous neutrophil apoptosis. PMID:31641174
The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. PMID:31640799
Autophagy is required for sulfur dioxide tolerance in Saccharomyces cerevisiae. PMID:31638329
Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion. PMID:31615920
Identification of key candidate genes and pathways in glioblastoma by integrated bioinformatical analysis. PMID:31602219
Systematic profiling of alternative splicing events and splicing factors in left- and right-sided colon cancer. PMID:31586988
Identification of potential diagnostic and prognostic biomarkers for prostate cancer. PMID:31579071
Screening and Identification of Potential Prognostic Biomarkers in Adrenocortical Carcinoma. PMID:31572440
Global Proteome of LonP1+/- Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes. PMID:31547314
Microarray‑based analysis of COL11A1 and TWIST1 as important differentially‑expressed pathogenic genes between left and right‑sided colon cancer. PMID:31545476
Bioinformatic identification of key candidate genes and pathways in axon regeneration after spinal cord injury in zebrafish. PMID:31535658
Identification of Key Pathways and Genes of Acute Respiratory Distress Syndrome Specific Neutrophil Phenotype. PMID:31531373
Bioinformatics and functional analyses of key genes in smoking-associated lung adenocarcinoma. PMID:31516576
Prognostic value and immune infiltration of novel signatures in clear cell renal cell carcinoma microenvironment. PMID:31493764
Integrative genomics analysis of hub genes and their relationship with prognosis and signaling pathways in esophageal squamous cell carcinoma. PMID:31485619
Structure to function analysis with antigenic characterization of a hypothetical protein,HPAG1_0576 from Helicobacter pylori HPAG1. PMID:31485131
Combination treatment with n-3 polyunsaturated fatty acids and ursodeoxycholic acid dissolves cholesterol gallstones in mice. PMID:31484954
Papillary Renal Cell Carcinomas Rewire Glutathione Metabolism and Are Deficient in Both Anabolic Glucose Synthesis and Oxidative Phosphorylation. PMID:31484429
Breakdown of multiple sclerosis genetics to identify an integrated disease network and potential variant mechanisms. PMID:31482761
DNA Methylation Biomarkers Predict Objective Responses to PD-1/PD-L1 Inhibition Blockade. PMID:31475034
Neutrophil-Derived Reactive Oxygen Orchestrates Epithelial Cell Signaling Events during Intestinal Repair. PMID:31472109
Gene Expression Predicts Histological Severity and Reveals Distinct Molecular Profiles of Nonalcoholic Fatty Liver Disease. PMID:31467298
Prim-O-glucosylcimifugin enhances the antitumour effect of PD-1 inhibition by targeting myeloid-derived suppressor cells. PMID:31462297
Identification and characterization of biomarkers and their functions for docetaxel-resistant prostate cancer cells. PMID:31452801
N-Glycoproteomic Profiling Reveals Alteration In Extracellular Matrix Organization In Non-Type Bladder Carcinoma. PMID:31450586
Comparative multi-omics systems analysis reveal the glycolysis / gluconeogenesis signal pathway play an important role in virulence attenuation in fish-derived GBS YM001. PMID:31449567
Post-transcriptional Regulation of Colorectal Cancer: A Focus on RNA-Binding Proteins. PMID:31440515
A differential transcriptional profile by Culex quinquefasciatus larvae resistant to Lysinibacillus sphaericus IAB59 highlights genes and pathways associated with the resistance phenotype. PMID:31429782
Integral analyses of survival-related long non-coding RNA MIR210HG and its prognostic role in colon cancer. PMID:31423171
Integrated systems-genetic analyses reveal a network target for delaying glioma progression. PMID:31420939
mRNAs expression profiles of high glucose-induced memory in human umbilical vein endothelial cells. PMID:31413614
Identification of biomarkers, pathways and potential therapeutic agents for white adipocyte insulin resistance using bioinformatics analysis. PMID:31407623
Meta-analysis of gene expression alterations and clinical significance of the HECT domain-containing ubiquitin ligase HUWE1 in cancer. PMID:31404287
Construction of subtype-specific prognostic gene signatures for early-stage non-small cell lung cancer using meta feature selection methods. PMID:31402939
Analysis of Protein-Protein Functional Associations by Using Gene Ontology and KEGG Pathway. PMID:31396531
The Cross Talk between TbTim50 and PIP39, Two Aspartate-Based Protein Phosphatases, Maintains Cellular Homeostasis in Trypanosoma brucei. PMID:31391278
Connecting signaling and metabolic pathways in EGF receptor-mediated oncogenesis of glioblastoma. PMID:31386654
Avian Binocularity and Adaptation to Nocturnal Environments: Genomic Insights from a Highly Derived Visual Phenotype. PMID:31386143
Regulatory Network Analysis to Reveal Important miRNAs and Genes in Non-Small Cell Lung Cancer. PMID:31376328
The Evolution of Gene Duplicates in Angiosperms and the Impact of Protein-Protein Interactions and the Mechanism of Duplication. PMID:31364708
Reprogramming of gene expression in Escherichia coli cultured on pyruvate versus glucose. PMID:31363904
A Review of Bioinformatics Tools to Understand Acetaminophen-Alcohol Interaction. PMID:31349598
E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration. PMID:31341204
Diagnostic and prognostic values of integrin α subfamily mRNA expression in colon adenocarcinoma. PMID:31322253
Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism. PMID:31320750
Analysis of networks of host proteins in the early time points following HIV transduction. PMID:31315557
Long Noncoding RNA Expression Profile in BV2 Microglial Cells Exposed to Lipopolysaccharide. PMID:31309106
Identifying Cancer Driver lncRNAs Bridged by Functional Effectors through Integrating Multi-omics Data in Human Cancers. PMID:31302496
SerThr-PhosphoProteome of Brain from Aged PINK1-KO+A53T-SNCA Mice Reveals pT1928-MAP1B and pS3781-ANK2 Deficits, as Hub between Autophagy and Synapse Changes. PMID:31277379
RNA Sequencing of Osteosarcoma Gene Expression Profile Revealed that miR-214-3p Facilitates Osteosarcoma Cell Proliferation via Targeting Ubiquinol-Cytochrome c Reductase Core Protein 1 (UQCRC1). PMID:31276465
Transcriptome Profiling Reveals Pro-Inflammatory Cytokines and Matrix Metalloproteinase Activation in Zika Virus Infected Human Umbilical Vein Endothelial Cells. PMID:31249527
Identification of hub genes and key pathways associated with angioimmunoblastic T-cell lymphoma using weighted gene co-expression network analysis. PMID:31239775
Anticancer Effects of Emodin on HepG2 Cell: Evidence from Bioinformatic Analysis. PMID:31236404
Banking Mesenchymal Stromal Cells from Umbilical Cord Tissue: Large Sample Size Analysis Reveals Consistency Between Donors. PMID:31219684
Characterization of intellectual disability and autism comorbidity through gene panel sequencing. PMID:31209962
Combining learning and constraints for genome-wide protein annotation. PMID:31208327
CoCoScore: context-aware co-occurrence scoring for text mining applications using distant supervision. PMID:31199464
Analysis of the role of DAMTC in lung adenocarcinoma cells based on the DNA microarrays. PMID:31186684
Deciphering molecular mechanism of silver by integrated omic approaches enables enhancing its antimicrobial efficacy in E. coli. PMID:31181061
Differentially expressed genes between systemic sclerosis and rheumatoid arthritis. PMID:31178673
Transcriptome and Gene Coexpression Network Analyses of Two Wild Populations Provides Insight into the High-Salinity Adaptation Mechanisms of Crassostrea ariakensis. PMID:31165295
Analysis of a Protein Network Related to Copy Number Variations in Autism Spectrum Disorder. PMID:31161481
Transcriptome Analysis of the Breast Muscle of Xichuan Black-Bone Chickens Under Tyrosine Supplementation Revealed the Mechanism of Tyrosine-Induced Melanin Deposition. PMID:31156710
Phylogeny, Divergent Evolution, and Speciation of Sulfur-Oxidizing Acidithiobacillus Populations. PMID:31146680
Identification of hub genes and therapeutic drugs in esophageal squamous cell carcinoma based on integrated bioinformatics strategy. PMID:31139019
Genomic Characterization Provides New Insights for Detailed Phage- Resistant Mechanism for Brucella abortus. PMID:31130926
KEGG-expressed genes and pathways in intervertebral disc degeneration: Protocol for a systematic review and data mining. PMID:31124977
Collagen stiffness promoted non-muscle-invasive bladder cancer progression to muscle-invasive bladder cancer. PMID:31123405
Bioinformatics identification of microRNAs involved in polycystic ovary syndrome based on microarray data. PMID:31115532
Systems Biology Understanding of the Effects of Lithium on Cancer. PMID:31114752
Transcriptome profiling of dorsal root ganglia in a rat model of complex regional pain syndrome type-I reveals potential mechanisms involved in pain. PMID:31114302
Analysis of the autophagy gene expression profile of pancreatic cancer based on autophagy-related protein microtubule-associated protein 1A/1B-light chain 3. PMID:31114135
Analysis of the Human Kinome and Phosphatome by Mass Cytometry Reveals Overexpression-Induced Effects on Cancer-Related Signaling. PMID:31101498
scNPF: an integrative framework assisted by network propagation and network fusion for preprocessing of single-cell RNA-seq data. PMID:31068142
In Vivo Proteome of Pseudomonas aeruginosa in Airways of Cystic Fibrosis Patients. PMID:31060355
Identification of time‑series differentially expressed genes and pathways associated with heart failure post‑myocardial infarction using integrated bioinformatics analysis. PMID:31059043
LPI-IBNRA: Long Non-coding RNA-Protein Interaction Prediction Based on Improved Bipartite Network Recommender Algorithm. PMID:31057602
Usnic acid modifies MRSA drug resistance through down-regulation of proteins involved in peptidoglycan and fatty acid biosynthesis. PMID:31050202
The tomato Arp2/3 complex is required for resistance to the powdery mildew fungus Oidium neolycopersici. PMID:31038756
Evolutionary Analysis of Makorin Ring Finger Protein 3 Reveals Positive Selection in Mammals. PMID:31024214
Gene expression changes associated with the evolutionary loss of a metabolic trait: lack of lipogenesis in parasitoids. PMID:31014246
Identification of key candidate genes and pathways in oral squamous cell carcinoma by integrated Bioinformatics analysis. PMID:31007745
Identification of key pathways and genes in nasopharyngeal carcinoma using bioinformatics analysis. PMID:30988824
Identification of key genes involved in the metastasis of clear cell renal cell carcinoma. PMID:30988807
A quantitative analysis of heterogeneities and hallmarks in acute myelogenous leukaemia. PMID:30988472
In Silico Investigation of the Anti-Tumor Mechanisms of Epigallocatechin-3-Gallate. PMID:30979098
Identification of the GRAS gene family in the Brassica juncea genome provides insight into its role in stem swelling in stem mustard. PMID:30972257
Identification of monotonically differentially expressed genes for non-small cell lung cancer. PMID:30971213
Comparison of cytokine/chemokine levels in aqueous humor of primary open-angle glaucoma patients with positive or negative outcome following trabeculectomy. PMID:30967499
Dark Proteome Database: Studies on Dark Proteins. PMID:30934744
Identification of Triple-Negative Breast Cancer Genes and a Novel High-Risk Breast Cancer Prediction Model Development Based on PPI Data and Support Vector Machines. PMID:30930932
A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regions. PMID:30922963
Identification of pathways associated with chemosensitivity through network embedding. PMID:30893303
Deletion of the KH1 Domain of Fmr1 Leads to Transcriptional Alterations and Attentional Deficits in Rats. PMID:30877790
Long Noncoding RNA and Protein Interactions: From Experimental Results to Computational Models Based on Network Methods. PMID:30875752
Deep sequencing reveals microRNA signature is altered in the rat epididymis following bilateral castration. PMID:30859493
A network-based approach to identify DNA methylation and its involved molecular pathways in testicular germ cell tumors. PMID:30854095
A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP-1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation. PMID:30848916
Functional protein representations from biological networks enable diverse cross-species inference. PMID:30847485
Development of a multicellular pancreatic tumor microenvironment system using patient-derived tumor cells. PMID:30839006
Gene expression analysis reveals early dysregulation of disease pathways and links Chmp7 to pathogenesis of spinal and bulbar muscular atrophy. PMID:30837566
The temporal profile of activity-dependent presynaptic phospho-signalling reveals long-lasting patterns of poststimulus regulation. PMID:30822303
Bioinformatics analyses of differentially expressed genes associated with spinal cord injury: A microarray-based analysis in a mouse model. PMID:30804258
Magic roundabout is an endothelial-specific ohnolog of ROBO1 which neo-functionalized to an essential new role in angiogenesis. PMID:30802244
Testosterone Administration after Traumatic Brain Injury Reduces Mitochondrial Dysfunction and Neurodegeneration. PMID:30794079
Identification of Potential Key Genes and Pathways in Early-Onset Colorectal Cancer Through Bioinformatics Analysis. PMID:30786729
RNA-Seq Transcriptome Profiling of the Queen Scallop (Aequipecten opercularis) Digestive Gland after Exposure to Domoic Acid-Producing Pseudo-nitzschia. PMID:30736356
Identification of the targets of hematoporphyrin derivative in lung adenocarcinoma using integrated network analysis. PMID:30717818
Bioinformatics analysis to identify the key genes affecting the progression and prognosis of hepatocellular carcinoma. PMID:30705088
Prognostic values of GMPS, PR, CD40, and p21 in ovarian cancer. PMID:30701134
A SNP, Gene, and Polygenic Risk Score Approach of Oxytocin-Vasopressin Genes in Adolescents' Loneliness. PMID:30697859
Saccharomyces cerevisiae Cytosolic Thioredoxins Control Glycolysis, Lipid Metabolism, and Protein Biosynthesis under Wine-Making Conditions. PMID:30683739
Identification of differentially expressed genes and enriched pathways in lung cancer using bioinformatics analysis. PMID:30664219
Weighted gene co‑expression network analysis for identifying hub genes in association with prognosis in Wilms tumor. PMID:30664180
Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation. PMID:30655532
Biological Interpretation of Complex Genomic Data. PMID:30649721
Secretory High-Mobility Group Box 1 Protein Affects Regulatory T Cell Differentiation in Neuroblastoma Microenvironment In Vitro. PMID:30643519
Complex-centric proteome profiling by SEC-SWATH-MS. PMID:30642884
Identification of candidate diagnostic and prognostic biomarkers for pancreatic carcinoma. PMID:30639415
Heat stress induces proteomic changes in the liver and mammary tissue of dairy cows independent of feed intake: An iTRAQ study. PMID:30625175
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks. PMID:30622252
Systems Biology Understanding of the Effects of Lithium on Affective and Neurodegenerative Disorders. PMID:30618562
Interaction between TP53 and XRCC1 increases susceptibility to cervical cancer development: a case control study. PMID:30616520
Identification of potential drug targets and inhibitor of the pathogenic bacteria Shigella flexneri 2a through the subtractive genomic approach. PMID:30607324
Analysis of dynamic molecular networks for pancreatic ductal adenocarcinoma progression. PMID:30598639
Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis. PMID:30598580
Key regulator of cellular metabolism, estrogen-related receptor α, a new therapeutic target in endocrine-related gynecological tumor. PMID:30588094
Integrating Multiple Interaction Networks for Gene Function Inference. PMID:30577643
Investigation into the underlying molecular mechanisms of white adipose tissue through comparative transcriptome analysis of multiple tissues. PMID:30569103
Physiological and proteomic analysis on long-term drought resistance of cassava (Manihot esculenta Crantz). PMID:30568257
Transcriptionally dynamic progenitor populations organised around a stable niche drive axial patterning. PMID:30559277
Quantitative Phosphoproteomic and System-Level Analysis of TOR Inhibition Unravel Distinct Organellar Acclimation in Chlamydomonas reinhardtii. PMID:30546371
Network-based features enable prediction of essential genes across diverse organisms. PMID:30543651
Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer. PMID:30532555
GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis. PMID:30523250
Temporal proteomic profiling of postnatal human cortical development. PMID:30518843
Genome-wide identification and characterization of long non-coding RNAs during postnatal development of rabbit adipose tissue. PMID:30486837
A chemical genetic screen reveals a role for proteostasis in capsule and biofilm formation by Cryptococcus neoformans. PMID:30483521
STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets. PMID:30476243
CCNA2 acts as a novel biomarker in regulating the growth and apoptosis of colorectal cancer. PMID:30464611
Transcriptome and Resistance-Related Genes Analysis of Botrytis cinerea B05.10 Strain to Different Selective Pressures of Cyprodinil and Fenhexamid. PMID:30425701
Role of Overexpressed Transcription Factor FOXO1 in Fatal Cardiovascular Septal Defects in Patau Syndrome: Molecular and Therapeutic Strategies. PMID:30423812
Identification of DKK-1 as a novel mediator of statin effects in human endothelial cells. PMID:30420710
Identifying antimicrobial peptides using word embedding with deep recurrent neural networks. PMID:30418485
Transcriptome-based mining and expression profiling of Pythium responsive transcription factors in Zingiber sp. PMID:30415383
The Overexpression of CD80 and ISG15 Are Associated with the Progression and Metastasis of Breast Cancer by a Meta-Analysis Integrating Three Microarray Datasets. PMID:30411299
Identification of critically carcinogenesis-related genes in basal cell carcinoma. PMID:30410353
Exploring Pharmacological Mechanisms of Xuefu Zhuyu Decoction in the Treatment of Traumatic Brain Injury via a Network Pharmacology Approach. PMID:30402137
Limited short-term effects on human prostate cancer xenograft growth and epidermal growth factor receptor gene expression by the ghrelin receptor antagonist [D-Lys3]-GHRP-6. PMID:30390209
The Crabtree Effect Shapes the Saccharomyces cerevisiae Lag Phase during the Switch between Different Carbon Sources. PMID:30377274
cuRnet: an R package for graph traversing on GPU. PMID:30367572
Substrate Specificity Analysis of Dihydrofolate/Dihydromethanopterin Reductase Homologs in Methylotrophic α-Proteobacteria. PMID:30364315
Proteomic and metabolomic analysis of the cellular biomarkers related to inhibitors tolerance in Zymomonas mobilis ZM4. PMID:30356850
Ataxia telangiectasia alters the ApoB and reelin pathway. PMID:30343341
Distinct co-expression networks using multi-omic data reveal novel interventional targets in HPV-positive and negative head-and-neck squamous cell cancer. PMID:30323202
Systematic expression alteration analysis of master reprogramming factor OCT4 and its three pseudogenes in human cancer and their prognostic outcomes. PMID:30287838
Mesenchymal glioblastoma constitutes a major ceRNA signature in the TGF-β pathway. PMID:30279734
Additional common variants associated with type 2 diabetes and coronary artery disease detected using a pleiotropic cFDR method. PMID:30270018
Bioinformatics analysis to identify action targets in NCI-N87 gastric cancer cells exposed to quercetin. PMID:30266078
Darkness in the Human Gene and Protein Function Space: Widely Modest or Absent Illumination by the Life Science Literature and the Trend for Fewer Protein Function Discoveries Since 2000. PMID:30265449
Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy. PMID:30262818
Computational identification and analysis of neurodegenerative disease associated protein kinases in hominid genomes. PMID:30258892
Constitutive activation and overexpression of NF-κB/c-Rel in conjunction with p50 contribute to aggressive tongue tumorigenesis. PMID:30250646
Microscopic and Proteomic Analysis of Dissected Developing Barley Endosperm Layers Reveals the Starchy Endosperm as Prominent Storage Tissue for ER-Derived Hordeins Alongside the Accumulation of Barley Protein Disulfide Isomerase (HvPDIL1-1). PMID:30250475
Viruses.STRING: A Virus-Host Protein-Protein Interaction Database. PMID:30249048
Dissecting the Repertoire of DNA-Binding Transcription Factors of the Archaeon Pyrococcus furiosus DSM 3638. PMID:30248960
Proteomic variation in metamorphosing Paralichthys olivaceus induced by exogenous thyroid hormone. PMID:30242698
Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling. PMID:30239736
A pan-cancer atlas of cancer hallmark-associated candidate driver lncRNAs. PMID:30216655
MIEF1 Microprotein Regulates Mitochondrial Translation. PMID:30215512
Microarray data analysis to identify differentially expressed genes and biological pathways associated with asthma. PMID:30186379
Andrographolide Sulfonate Attenuates Acute Lung Injury by Reducing Expression of Myeloperoxidase and Neutrophil-Derived Proteases in Mice. PMID:30174607
Quantitative RNA-seq Analysis Unveils Osmotic and Thermal Adaptation Mechanisms Relevant for Ectoine Production in Chromohalobacter salexigens. PMID:30158907
Mechanisms of Huangqi Decoction Granules () on Hepatitis B Cirrhosis Patients Based on RNA-Sequencing. PMID:30155678
Region-Resolved Quantitative Proteome Profiling Reveals Molecular Dynamics Associated With Chronic Pain in the PNS and Spinal Cord. PMID:30154697
Bioinformatics Analysis of Key Differentially Expressed Genes in Nonalcoholic Fatty Liver Disease Mice Models. PMID:30135001
Bioinformatics analyses of significant genes, related pathways and candidate prognostic biomarkers in glioblastoma. PMID:30132538
Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers. PMID:30123424
Identification of target genes in cardiomyopathy with fibrosis and cardiac remodeling. PMID:30115125
Zearalenone Exposure Enhanced the Expression of Tumorigenesis Genes in Donkey Granulosa Cells via the PTEN/PI3K/AKT Signaling Pathway. PMID:30108608
Structure modeling to function prediction of Uncharacterized Human Protein C15orf41. PMID:30108417
Risk assessment model constructed by differentially expressed lncRNAs for the prognosis of glioma. PMID:30106138
In silico insights on diverse interacting partners and phosphorylation sites of respiratory burst oxidase homolog (Rbohs) gene families from Arabidopsis and rice. PMID:30097007
Analysis of differentially expressed genes among human hair follicle-derived iPSCs, induced hepatocyte-like cells, and primary hepatocytes. PMID:30092828
Signals involved in the effects of bisphenol A (BPA) on proliferation and motility of Leydig cells: a comparative proteomic analysis. PMID:30090458
Gender specific differences in the liver proteome of rats exposed to short term and low-concentration hexabromocyclododecane (HBCD). PMID:30090431
Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids. PMID:30090399
Identification of Critical Genes and miRNAs Associated with the Development of Parkinson's Disease. PMID:30083784
Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart. PMID:30061404
Characterizing functional consequences of DNA copy number alterations in breast and ovarian tumors by spaceMap. PMID:30057342
An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome. PMID:30057032
Transcriptomic Analysis of Hepatic Cells in Multicellular Organotypic Liver Models. PMID:30054499
Understanding the role of interactions between host and Mycobacterium tuberculosis under hypoxic condition: an in silico approach. PMID:30053801
Extracting proteins involved in disease progression using temporally connected networks. PMID:30045727
Integrating Rio1 activities discloses its nutrient-activated network in Saccharomyces cerevisiae. PMID:30011030
Bid Expression Network Controls Neuronal Cell Fate During Avian Ciliary Ganglion Development. PMID:30008673
A Novel Differential Ion Mobility Device Expands the Depth of Proteome Coverage and the Sensitivity of Multiplex Proteomic Measurements. PMID:30007914
Radio-sensitizing effects of VE-821 and beyond: Distinct phosphoproteomic and metabolomic changes after ATR inhibition in irradiated MOLT-4 cells. PMID:30001349
Expression of microRNA-99a-3p in Prostate Cancer Based on Bioinformatics Data and Meta-Analysis of a Literature Review of 965 Cases. PMID:29997385
Bioinformatics analysis to reveal the key genes related to obstructive sleep apnea. PMID:29992456
Identification of Hub Genes and Key Pathways Associated with Two Subtypes of Diffuse Large B-Cell Lymphoma Based on Gene Expression Profiling via Integrated Bioinformatics. PMID:29992138
A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease. PMID:29988083
Expression and network analysis of YBX1 interactors for identification of new drug targets in lung adenocarcinoma. PMID:29973960
Differential Integration of Transcriptome and Proteome Identifies Pan-Cancer Prognostic Biomarkers. PMID:29971090
Novel insights into global translational regulation through Pumilio family RNA-binding protein Puf3p revealed by ribosomal profiling. PMID:29951697
Gallid Herpesvirus 1 Initiates Apoptosis in Uninfected Cells through Paracrine Repression of p53. PMID:29950417
Functional annotation of hypothetical proteins from the Exiguobacterium antarcticum strain B7 reveals proteins involved in adaptation to extreme environments, including high arsenic resistance. PMID:29940001
In Silico Genome-Wide Analysis Reveals the Potential Links Between Core Genome of Acidithiobacillus thiooxidans and Its Autotrophic Lifestyle. PMID:29937764
High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration. PMID:29936182
Exploring the molecular pathogenesis associated with T-cell prolymphocytic leukemia based on a comprehensive bioinformatics analysis. PMID:29928415
Dysregulated genes targeted by microRNAs and metabolic pathways in bladder cancer revealed by bioinformatics methods. PMID:29928337
Integration of proteomic and transcriptomic profiles reveals multiple levels of genetic regulation of salt tolerance in cotton. PMID:29925319
Natural cyclopeptide RA-V inhibits the NF-κB signaling pathway by targeting TAK1. PMID:29915207
Identification and functional analysis of differentially expressed genes associated with cerebral ischemia/reperfusion injury through bioinformatics methods. PMID:29901134
Proteomic comparison of the EWS-FLI1 expressing cells EF with NIH-3T3 and actin remodeling effect of (R/W)9 cell-penetrating peptide. PMID:29900093
Differential network as an indicator of osteoporosis with network entropy. PMID:29896257
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. PMID:29895827
Genomic atlas of the human plasma proteome. PMID:29875488
deepNF: deep network fusion for protein function prediction. PMID:29868758
Meta-Analysis of Maternal and Fetal Transcriptomic Data Elucidates the Role of Adaptive and Innate Immunity in Preterm Birth. PMID:29867970
Toll-Like Receptors Drive Specific Patterns of Tolerance and Training on Restimulation of Macrophages. PMID:29867935
Host Interaction Analysis of PA-N155 and PA-N182 in Chicken Cells Reveals an Essential Role of UBA52 for Replication of H5N1 Avian Influenza Virus. PMID:29867845
Melittin Constrains the Expression of Identified Key Genes Associated with Bladder Cancer. PMID:29854840
MicroRNA Expression Profiling in Behçet's Disease. PMID:29854829
Gene Expression Profiling in Behcet's Disease Indicates an Autoimmune Component in the Pathogenesis of the Disease and Opens New Avenues for Targeted Therapy. PMID:29850627
MicroRNA Expression Profiling in Psoriatic Arthritis. PMID:29850558
Finding novel relationships with integrated gene-gene association network analysis of Synechocystis sp. PCC 6803 using species-independent text-mining. PMID:29844966
Identification of key genes and pathways in meningioma by bioinformatics analysis. PMID:29805558
Identification of key candidate genes and pathways in hepatocellular carcinoma by integrated bioinformatical analysis. PMID:29805517
Identification of Biological Targets of Therapeutic Intervention for Hepatocellular Carcinoma by Integrated Bioinformatical Analysis. PMID:29795057
Quantitative SUMO proteomics reveals the modulation of several PML nuclear body associated proteins and an anti-senescence function of UBC9. PMID:29773808
Cellular stress responses to chronic heat shock and shell damage in temperate Mya truncata. PMID:29754331
Microarray‑based bioinformatics analysis of the prospective target gene network of key miRNAs influenced by long non‑coding RNA PVT1 in HCC. PMID:29749550
Integrated bioinformatics analysis reveals that the expression of cathepsin S is associated with lymph node metastasis and poor prognosis in papillary thyroid cancer. PMID:29749483
The genetic architecture of floral traits in the woody plant Prunus mume. PMID:29703940
ParaBTM: A Parallel Processing Framework for Biomedical Text Mining on Supercomputers. PMID:29702574
The Correlation Between the Immune and Epithelial-Mesenchymal Transition Signatures Suggests Potential Therapeutic Targets and Prognosis Prediction Approaches in Kidney Cancer. PMID:29700419
Identifying genes as potential prognostic indicators in patients with serous ovarian cancer resistant to carboplatin using integrated bioinformatics analysis. PMID:29693178
Identification of Key Candidate Proteins and Pathways Associated with Temozolomide Resistance in Glioblastoma Based on Subcellular Proteomics and Bioinformatical Analysis. PMID:29687002
Comparative genomics of the wheat fungal pathogen Pyrenophora tritici-repentis reveals chromosomal variations and genome plasticity. PMID:29685100
Global Effects of DDX3 Inhibition on Cell Cycle Regulation Identified by a Combined Phosphoproteomics and Single Cell Tracking Approach. PMID:29684792
Navigating the disease landscape: knowledge representations for contextualizing molecular signatures. PMID:29684165
A Systems Approach to Refine Disease Taxonomy by Integrating Phenotypic and Molecular Networks. PMID:29669699
Investigating multiple dysregulated pathways in rheumatoid arthritis based on pathway interaction network. PMID:29666336
Upregulation of HOXA1 promotes tumorigenesis and development of non‑small cell lung cancer: A comprehensive investigation based on reverse transcription-quantitative polymerase chain reaction and bioinformatics analysis. PMID:29658571
Pan-Genome Analysis Links the Hereditary Variation of Leptospirillum ferriphilum With Its Evolutionary Adaptation. PMID:29636744
SUMO1-conjugation is altered during normal aging but not by increased amyloid burden. PMID:29633471
Identification of key genes in non‑alcoholic fatty liver disease progression based on bioinformatics analysis. PMID:29620197
Exploring the molecular mechanisms of osteosarcoma by the integrated analysis of mRNAs and miRNA microarrays. PMID:29620143
A comprehensive analysis of the predicted targets of miR-642b-3p associated with the long non-coding RNA HOXA11-AS in NSCLC cells. PMID:29616096
Systematic Evaluation of Molecular Networks for Discovery of Disease Genes. PMID:29605183
Comprehensive analysis of Helicobacter pylori infection-associated diseases based on miRNA-mRNA interaction network. PMID:29579224
Long non-coding RNAs RP5-821D11.7, APCDD1L-AS1 and RP11-277P12.9 were associated with the prognosis of lung squamous cell carcinoma. PMID:29568882
The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells. PMID:29568765
Gene Profiling in Patients with Systemic Sclerosis Reveals the Presence of Oncogenic Gene Signatures. PMID:29559981
PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT. PMID:29559632
Identification of prefrontal cortex protein alterations in Alzheimer's disease. PMID:29541381
Transcriptomic Analysis Reveal the Molecular Mechanisms of Wheat Higher-Temperature Seedling-Plant Resistance to Puccinia striiformis f. sp. tritici. PMID:29541084
Exploring the Molecular Mechanism of Thoracic Aortic Aneurysm via Bioinformatics Analysis. PMID:29538353
Promyelocytic Leukemia Protein (PML) Requirement for Interferon-induced Global Cellular SUMOylation. PMID:29535160
Chemokine expression in the early response to injury in human airway epithelial cells. PMID:29534074
p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage. PMID:29523821
An uncertain model-based approach for identifying dynamic protein complexes in uncertain protein-protein interaction networks. PMID:29513194
The chemokine receptor CCR1 is identified in mast cell-derived exosomes. PMID:29511430
Phenotype-driven identification of epithelial signalling clusters. PMID:29507319
Genome-wide identification and expression analysis of GRAS family transcription factors in tea plant (Camellia sinensis). PMID:29500448
Investigation of hypoxia networks in ovarian cancer via bioinformatics analysis. PMID:29482638
Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. PMID:29467282
A novel heterogeneous network-based method for drug response prediction in cancer cell lines. PMID:29463808
Effect of ovarian cancer ascites on SKOV-3 cells proteome: new proteins associated with aggressive phenotype in epithelial ovarian cancer. PMID:29456457
A comprehensive and quantitative comparison of text-mining in 15 million full-text articles versus their corresponding abstracts. PMID:29447159
Oasis 2: improved online analysis of small RNA-seq data. PMID:29444641
Screening of FOXD3 targets in lung cancer via bioinformatics analysis. PMID:29435060
Identification of core pathways based on attractor and crosstalk in ischemic stroke. PMID:29434737
Retinal progenitor cells release extracellular vesicles containing developmental transcription factors, microRNA and membrane proteins. PMID:29434302
A large-scale RNA interference screen identifies genes that regulate autophagy at different stages. PMID:29434216
Proteome Data Improves Protein Function Prediction in the Interactome of Helicobacter pylori. PMID:29414760
Transcriptome of Porcine PBMCs over Two Generations Reveals Key Genes and Pathways Associated with Variable Antibody Responses post PRRSV Vaccination. PMID:29410429
Integrated Modules Analysis to Explore the Molecular Mechanisms of Phlegm-Stasis Cementation Syndrome with Ischemic Heart Disease. PMID:29403392
Identification of candidate genes that may contribute to the metastasis of prostate cancer by bioinformatics analysis. PMID:29399176
Identification of key genes associated with bladder cancer using gene expression profiles. PMID:29375713
Revealing the action mechanisms of dexamethasone on the birth weight of infant using RNA-sequencing data of trophoblast cells. PMID:29369181
Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome. PMID:29357390
Comprehensive list of SUMO targets in Caenorhabditis elegans and its implication for evolutionary conservation of SUMO signaling. PMID:29348603
Platelet protein biomarker panel for ovarian cancer diagnosis. PMID:29344361
Identification and functional analysis of risk-related microRNAs for the prognosis of patients with bladder urothelial carcinoma. PMID:29344166
To Explore the Mechanism of the GRM4 Gene in Osteosarcoma by RNA Sequencing and Bioinformatics Approach. PMID:29339716
Network-Based Methods for Identifying Key Active Proteins in the Extracellular Electron Transfer Process in Shewanella oneidensis MR-1. PMID:29337910
Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in glioblastoma. PMID:29335913
Transcriptomics Evidence for Common Pathways in Human Major Depressive Disorder and Glioblastoma. PMID:29329273
Integrative gene ontology and network analysis of coronary artery disease associated genes suggests potential role of ErbB pathway gene EGFR. PMID:29328373
Genome-Wide Methylation Patterns in Androgen-Independent Prostate Cancer Cells: A Comprehensive Analysis Combining MeDIP-Bisulfite, RNA, and microRNA Sequencing Data. PMID:29324665
Assessing the Performances of Protein Function Prediction Algorithms from the Perspectives of Identification Accuracy and False Discovery Rate. PMID:29316706
Transcriptomic Analysis of Intestinal Tissues from Two 90-Day Feeding Studies in Rats Using Genetically Modified MON810 Maize Varieties. PMID:29312443
Lysine Succinylation Contributes to Aflatoxin Production and Pathogenicity in Aspergillus flavus. PMID:29298838
Biomarkers for tissue engineering of the tendon-bone interface. PMID:29298298
Functional and DNA-protein binding studies of WRKY transcription factors and their expression analysis in response to biotic and abiotic stress in wheat (Triticum aestivum L.). PMID:29291153
Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione. PMID:29285300
The integration of weighted gene association networks based on information entropy. PMID:29272314
Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis. PMID:29262532
Exploring of the molecular mechanism of rhinitis via bioinformatics methods. PMID:29257233
Estrogen exposure overrides the masculinizing effect of elevated temperature by a downregulation of the key genes implicated in sexual differentiation in a fish with mixed genetic and environmental sex determination. PMID:29254503
Electronic Northern Analysis of Genes and Modeling of Gene Networks Underlying Bovine Milk Fat Production. PMID:29250447
Co-expression Network Approach Reveals Functional Similarities among Diseases Affecting Human Skeletal Muscle. PMID:29249983
The phosphorelay signal transduction system in Candida glabrata: an in silico analysis. PMID:29248994
An integrative analysis of DNA methylation in osteosarcoma. PMID:29234590
KiPho: malaria parasite kinome and phosphatome portal. PMID:29220464
Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach. PMID:29215067
Perturbation of Wound Healing, Cytoskeletal Organization and Cellular Protein Networks during Hazara Virus Infection. PMID:29209610
Identification of key genes influenced by fixation stability in early fracture hematoma and elucidation of their roles in fracture healing. PMID:29201161
Novel Common Variants Associated with Obesity and Type 2 Diabetes Detected Using a cFDR Method. PMID:29180724
Maximum-likelihood approaches reveal signatures of positive selection in BMP15 and GDF9 genes modulating ovarian function in mammalian female fertility. PMID:29177034
Functional diversity of topological modules in human protein-protein interaction networks. PMID:29170401
Quantitative Phosphoproteomic Analysis Reveals Shared and Specific Targets of Arabidopsis Mitogen-Activated Protein Kinases (MAPKs) MPK3, MPK4, and MPK6. PMID:29167316
Integrative analysis of novel hypomethylation and gene expression signatures in glioblastomas. PMID:29163774
Using molecular functional networks to manifest connections between obesity and obesity-related diseases. PMID:29156709
Association of Omics Features with Histopathology Patterns in Lung Adenocarcinoma. PMID:29153840
Discovery of Bladder Cancer-related Genes Using Integrative Heterogeneous Network Modeling of Multi-omics Data. PMID:29142286
Assigning chemoreceptors to chemosensory pathways in Pseudomonas aeruginosa. PMID:29133402
Comprehensive genomic analysis of the CNGC gene family in Brassica oleracea: novel insights into synteny, structures, and transcript profiles. PMID:29132315
Apolipoprotein C-III in the high-density lipoprotein proteome of cerebral lacunar infarction patients impairs its anti-inflammatory function. PMID:29115584
Identification of key genes, transcription factors and microRNAs involved in intracranial aneurysm. PMID:29115560
Screening of potential therapy targets for prostate cancer using integrated analysis of two gene expression profiles. PMID:29113170
Insight into glucocorticoid receptor signalling through interactome model analysis. PMID:29107989
Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development. PMID:29107595
The UCSC Genome Browser database: 2018 update. PMID:29106570
Bioinformatic Analysis Identifies Three Potentially Key Differentially Expressed Genes in Peripheral Blood Mononuclear Cells of Patients with Takayasu's Arteritis. PMID:29105401
Differentially expressed genes in the caecal and colonic mucosa of Landrace finishing pigs with high and low food conversion ratios. PMID:29097775
Genome-wide identification and expression analysis of glutathione S-transferase gene family in tomato: Gaining an insight to their physiological and stress-specific roles. PMID:29095889
Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor. PMID:29063678
Identification of candidate genes related to pancreatic cancer based on analysis of gene co-expression and protein-protein interaction network. PMID:29050346
CANcer-specific Evaluation System (CANES): a high-accuracy platform, for preclinical single/multi-biomarker discovery. PMID:29050243
Proteomics analysis of bladder cancer invasion: Targeting EIF3D for therapeutic intervention. PMID:29050215
Pumilio2-deficient mice show a predisposition for epilepsy. PMID:29046322
Proteomic analysis of human lacrimal and tear fluid in dry eye disease. PMID:29042648
Long non‑coding RNA HOTTIP promotes hepatocellular carcinoma tumorigenesis and development: A comprehensive investigation based on bioinformatics, qRT‑PCR and meta‑analysis of 393 cases. PMID:29039502
Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer. PMID:29032074
Single-cell RNA-seq reveals a distinct transcriptome signature of aneuploid hematopoietic cells. PMID:29030335
Review of computational methods for virus-host protein interaction prediction: a case study on novel Ebola-human interactions. PMID:29028879
Low-Grade Dysplastic Nodules Revealed as the Tipping Point during Multistep Hepatocarcinogenesis by Dynamic Network Biomarkers. PMID:29027943
Prediction of Human Phenotype Ontology terms by means of hierarchical ensemble methods. PMID:29025394
Quantitative phosphoproteomics reveals involvement of multiple signaling pathways in early phagocytosis by the retinal pigmented epithelium. PMID:28978645
Docking of CDK1 with antibiotic drugs revealed novel therapeutic value in breast ductal cancer in situ. PMID:28977921
Network-Based Method for Identifying Co- Regeneration Genes in Bone, Dentin, Nerve and Vessel Tissues. PMID:28974058
Genome-wide analysis of DNA Methylation profiles on sheep ovaries associated with prolificacy using whole-genome Bisulfite sequencing. PMID:28969601
RNA-seq based gene expression analysis of ovarian granulosa cells exposed to zearalenone in vitro: significance to steroidogenesis. PMID:28969048
Formation of a TBX20-CASZ1 protein complex is protective against dilated cardiomyopathy and critical for cardiac homeostasis. PMID:28945738
Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts. PMID:28939891
The highly expressed COL4A1 genes contributes to the proliferation and migration of the invasive ductal carcinomas. PMID:28938546
Integrated network analysis to explore the key genes regulated by parathyroid hormone receptor 1 in osteosarcoma. PMID:28934958
PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways across Biological Sex and Modes of Trauma. PMID:28925389
RNA-seq analysis of the kidneys of broiler chickens fed diets containing different concentrations of calcium. PMID:28924246
Comparative Genomic Analysis of the Human Gut Microbiome Reveals a Broad Distribution of Metabolic Pathways for the Degradation of Host-Synthetized Mucin Glycans and Utilization of Mucin-Derived Monosaccharides. PMID:28912798
Dynamic Changes in the Splenic Transcriptome of Chickens during the Early Infection and Progress of Marek's Disease. PMID:28912500
Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer. PMID:28904337
Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis. PMID:28903739
Screening and identification of key biomarkers in hepatocellular carcinoma: Evidence from bioinformatic analysis. PMID:28901457
Identification of genes associated with castration‑resistant prostate cancer by gene expression profile analysis. PMID:28901445
Integration of deep transcriptome and proteome analyses of salicylic acid regulation high temperature stress in Ulva prolifera. PMID:28887495
Mapping the STK4/Hippo signaling network in prostate cancer cell. PMID:28880957
α7 nicotinic acetylcholine receptor signaling modulates the inflammatory phenotype of fetal brain microglia: first evidence of interference by iron homeostasis. PMID:28878260
Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology. PMID:28874689
Phylo_dCor: distance correlation as a novel metric for phylogenetic profiling. PMID:28870256
Targeting mitochondrial translation by inhibiting DDX3: a novel radiosensitization strategy for cancer treatment. PMID:28869602
Transcriptome analysis of ankylosing spondylitis patients before and after TNF-α inhibitor therapy reveals the pathways affected. PMID:28835680
Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. PMID:28831120
Genome-wide characterization of the WRKY gene family in radish (Raphanus sativus L.) reveals its critical functions under different abiotic stresses. PMID:28819820
Differential effect of TGFβ on the proteome of cancer associated fibroblasts and cancer epithelial cells in a co-culture approach - a short report. PMID:28808957
Molecular mechanisms of breast cancer metastasis by gene expression profile analysis. PMID:28791367
Analysis of salivary microRNA expression profiles and identification of novel biomarkers in esophageal cancer. PMID:28789354
A network-based method using a random walk with restart algorithm and screening tests to identify novel genes associated with Menière's disease. PMID:28787010
Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures. PMID:28775339
Enriching Traditional Protein-protein Interaction Networks with Alternative Conformations of Proteins. PMID:28775330
Non-conventional role of haemoglobin beta in breast malignancy. PMID:28772282
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation. PMID:28768533
Characterization and predicted role of microRNA expression profiles associated with early childhood obesity. PMID:28765929
Double impact: natural molluscicide for schistosomiasis vector control also impedes development of Schistosoma mansoni cercariae into adult parasites. PMID:28753630
VEGFA Involves in the Use of Fluvastatin and Zoledronate Against Breast Cancer. PMID:28744693
Transcriptome Analysis of Canine Cutaneous Melanoma and Melanocytoma Reveals a Modulation of Genes Regulating Extracellular Matrix Metabolism and Cell Cycle. PMID:28743863
Capturing protein communities by structural proteomics in a thermophilic eukaryote. PMID:28743795
Network based subcellular proteomics in monocyte membrane revealed novel candidate genes involved in osteoporosis. PMID:28741036
Breast cancer cell adhesome and degradome interact to drive metastasis. PMID:28721370
Random mutagenesis analysis and identification of a novel C2H2-type transcription factor from the nematode-trapping fungus Arthrobotrys oligospora. PMID:28717216
Comparison of gene expression profiles between dental pulp and periodontal ligament tissues in humans. PMID:28713908
GeNNet: an integrated platform for unifying scientific workflows and graph databases for transcriptome data analysis. PMID:28695067
Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder. PMID:28688579
Identification of key genes and molecular mechanisms associated with dedifferentiated liposarcoma based on bioinformatic methods. PMID:28670134
[Screening of biomarkers related with leukocyte responses early after burn injury in mice by differential gene expression profiling]. PMID:28669950
FlyExpress 7: An Integrated Discovery Platform To Study Coexpressed Genes Using in Situ Hybridization Images in Drosophila. PMID:28667017
Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes. PMID:28664195
Quantitative proteomics analysis of proteins involved in alkane uptake comparing the profiling of Pseudomonas aeruginosa SJTD-1 in response to n-octadecane and n-hexadecane. PMID:28662172
Sitagliptin ameliorates oxidative stress in experimental diabetic nephropathy by diminishing the miR-200a/Keap-1/Nrf2 antioxidant pathway. PMID:28652790
Functional annotation of Alzheimer's disease associated loci revealed by GWASs. PMID:28650998
Data from salivary gland proteome analysis of female Aedes aegypti Linn. PMID:28649586
Comparative transcriptomic analysis of Gardnerella vaginalis biofilms vs. planktonic cultures using RNA-seq. PMID:28649404
Transcriptome profiling of 3D co-cultured cardiomyocytes and endothelial cells under oxidative stress using a photocrosslinkable hydrogel system. PMID:28648749
A multidimensional integration analysis reveals potential bridging targets in the process of colorectal cancer liver metastasis. PMID:28628609
Data mining and pathway analysis of glucose-6-phosphate dehydrogenase with natural language processing. PMID:28627690
Bioinformatics analysis of transcription profiling of solid pseudopapillary neoplasm of the pancreas. PMID:28627654
A knowledge-based T2-statistic to perform pathway analysis for quantitative proteomic data. PMID:28622336
Tag SNP selection for prediction of tick resistance in Brazilian Braford and Hereford cattle breeds using Bayesian methods. PMID:28619006
Identifying prognostic signature in ovarian cancer using DirGenerank. PMID:28615526
Identification of molecular biomarkers for pancreatic cancer with mRMR shortest path method. PMID:28611293
RNA-Sequence Analysis Reveals Differentially Expressed Genes (DEGs) in Patients Exhibiting Different Risks of Tumor Metastasis. PMID:28601889
Quantitative Proteomics Shows Extensive Remodeling Induced by Nitrogen Limitation in Prochlorococcusmarinus SS120. PMID:28593196
Multi-omics analysis provides insight to the Ignicoccus hospitalis-Nanoarchaeum equitans association. PMID:28591626
Colonic Phenotypes Are Associated with Poorer Response to Anti-TNF Therapies in Patients with IBD. PMID:28590340
Identification and functional analysis of the risk microRNAs associated with cerebral low-grade glioma prognosis. PMID:28586047
Elevated Levels of Proinflammatory Cytokines in Cerebrospinal Fluid of Multiple Sclerosis Patients. PMID:28572801
Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death. PMID:28562344
Platelet proteome reveals novel pathways of platelet activation and platelet-mediated immunoregulation in dengue. PMID:28542641
PPARD is an Inhibitor of Cartilage Growth in External Ears. PMID:28539839
Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence. PMID:28536560
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug. PMID:28530702
Comparative Genomics Unravels the Functional Roles of Co-occurring Acidophilic Bacteria in Bioleaching Heaps. PMID:28529505
Bioinformatics analysis of dysregulated microRNAs in the nipple discharge of patients with breast cancer. PMID:28521415
Silencing TAK1 alters gene expression signatures in bladder cancer cells. PMID:28521404
Architecture of the human interactome defines protein communities and disease networks. PMID:28514442
Decoding the complex genetic causes of heart diseases using systems biology. PMID:28509974
Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis. PMID:28506991
Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties. PMID:28504705
A Systemic Analysis of Transcriptomic and Epigenomic Data To Reveal Regulation Patterns for Complex Disease. PMID:28500050
The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior. PMID:28499923
Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea. PMID:28491023
In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4) as prognostic biomarker in several malignancies. PMID:28484222
From protein-protein interactions to protein co-expression networks: a new perspective to evaluate large-scale proteomic data. PMID:28477207
Overexpression of RKIP and its cross-talk with several regulatory gene products in multiple myeloma. PMID:28476134
In silico target network analysis of de novo-discovered, tick saliva-specific microRNAs reveals important combinatorial effects in their interference with vertebrate host physiology. PMID:28473453
Identifying novel fruit-related genes in Arabidopsis thaliana based on the random walk with restart algorithm. PMID:28472169
Computational Analysis of Host-Pathogen Protein Interactions between Humans and Different Strains of Enterohemorrhagic Escherichia coli. PMID:28469995
Protein signature characterizing Helicobacter pylori strains of patients with autoimmune atrophic gastritis, duodenal ulcer and gastric cancer. PMID:28465717
Insights into a key sulfite scavenger enzyme sulfite oxidase (SOX) gene in plants. PMID:28461726
Co-occurring protein phosphorylation are functionally associated. PMID:28459814
Transcriptomic and proteomic insight into the effects of a defined European mistletoe extract in Ewing sarcoma cells reveals cellular stress responses. PMID:28454538
Ref-1/APE1 as a Transcriptional Regulator and Novel Therapeutic Target in Pediatric T-cell Leukemia. PMID:28446640
Gene Expression Analysis before and after Treatment with Adalimumab in Patients with Ankylosing Spondylitis Identifies Molecular Pathways Associated with Response to Therapy. PMID:28441778
Identification of potential gene targets in systemic vasculitis using DNA microarray analysis. PMID:28440408
Identification of key genes associated with Schmid-type metaphyseal chondrodysplasia based on microarray data. PMID:28440393
Bioinformatics analysis of key genes and latent pathway interactions based on the anaplastic thyroid carcinoma gene expression profile. PMID:28428828
Transcriptional landscape of human cancers. PMID:28427185
Novel interactions of the von Hippel-Lindau (pVHL) tumor suppressor with the CDKN1 family of cell cycle inhibitors. PMID:28425505
Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer. PMID:28423713
Identification of protein clusters predictive of tumor response in rectal cancer patients receiving neoadjuvant chemo-radiotherapy. PMID:28423701
Transcriptome Sequencing of Dianthus spiculifolius and Analysis of the Genes Involved in Responses to Combined Cold and Drought Stress. PMID:28420173
Inferring modulators of genetic interactions with epistatic nested effects models. PMID:28406896
Microarray‑based screening of differentially expressed genes in glucocorticoid‑induced avascular necrosis. PMID:28393228
Cinnamaldehyde and eugenol change the expression folds of AKT1 and DKC1 genes and decrease the telomere length of human adipose-derived stem cells (hASCs): An experimental and in silico study. PMID:28392905
Transcriptomic buffering of cryptic genetic variation contributes to meningococcal virulence. PMID:28388876
Integrated network analysis reveals potentially novel molecular mechanisms and therapeutic targets of refractory epilepsies. PMID:28388656
Protease-Inhibitor Interaction Predictions: Lessons on the Complexity of Protein-Protein Interactions. PMID:28385878
An integrated method for the identification of novel genes related to oral cancer. PMID:28384236
Phosphoproteome Profiling Reveals Circadian Clock Regulation of Posttranslational Modifications in the Murine Hippocampus. PMID:28382018
Genome-wide DNA methylation profiles reveal novel candidate genes associated with meat quality at different age stages in hens. PMID:28378745
PINTnet: construction of condition-specific pathway interaction network by computing shortest paths on weighted PPI. PMID:28361687
Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. PMID:28356702
A Novel Pan-Genome Reverse Vaccinology Approach Employing a Negative-Selection Strategy for Screening Surface-Exposed Antigens against leptospirosis. PMID:28352257
Identification of Key Candidate Genes and Pathways in Colorectal Cancer by Integrated Bioinformatical Analysis. PMID:28350360
Cardioprotection Effects of Sevoflurane by Regulating the Pathway of Neuroactive Ligand-Receptor Interaction in Patients Undergoing Coronary Artery Bypass Graft Surgery. PMID:28348638
The autophagy interaction network of the aging model Podospora anserina. PMID:28347269
Smoking-Dependent Distal-to-Proximal Repatterning of the Adult Human Small Airway Epithelium. PMID:28345955
Quantitative Tyrosine Phosphoproteomics of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor-treated Lung Adenocarcinoma Cells Reveals Potential Novel Biomarkers of Therapeutic Response. PMID:28331001
Correlated duplications and losses in the evolution of palmitoylation writer and eraser families. PMID:28320309
Vector Integration Sites Identification for Gene-Trap Screening in Mammalian Haploid Cells. PMID:28303933
Identification of lymph node metastasis-related microRNAs in lung adenocarcinoma and analysis of the underlying mechanisms using a bioinformatics approach. PMID:28299977
Identification of Candidate Genes Related to Inflammatory Bowel Disease Using Minimum Redundancy Maximum Relevance, Incremental Feature Selection, and the Shortest-Path Approach. PMID:28293637
Microarray Integrated Analysis of a Gene Network for the CD36 Myocardial Phenotype. PMID:28293076
Comprehensive discovery of subsample gene expression components by information explanation: therapeutic implications in cancer. PMID:28292312
Analysis of MicroRNA-mRNA Interactions in Stem Cell-Enriched Fraction of Oral Squamous Cell Carcinoma. PMID:28276309
Early spatiotemporal-specific changes in intermediate signals are predictive of cytotoxic sensitivity to TNFα and co-treatments. PMID:28272488
Identifying protein kinase-specific effectors of the osmostress response in yeast. PMID:28270554
A temporal proteome dynamics study reveals the molecular basis of induced phenotypic resistance in Mycobacterium smegmatis at sub-lethal rifampicin concentrations. PMID:28262820
GenePANDA-a novel network-based gene prioritizing tool for complex diseases. PMID:28252032
Concurrent Label-Free Mass Spectrometric Analysis of Dystrophin Isoform Dp427 and the Myofibrosis Marker Collagen in Crude Extracts from mdx-4cv Skeletal Muscles. PMID:28248273
Proteomic analysis and cross species comparison of casein fractions from the milk of dairy animals. PMID:28240229
Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors. PMID:28239758
Genome Wide In silico Analysis of the Mismatch Repair Components of Plasmodium falciparum and Their Comparison with Human Host. PMID:28232818
Analysis of gene expression changes associated with human carcinoma-associated fibroblasts in non-small cell lung carcinoma. PMID:28231844
Exploration of inhibitory mechanisms of curcumin in lung cancer metastasis using a miRNA- transcription factor-target gene network. PMID:28231299
Decoding the Molecular and Mutational Ambiguities of Gastroenteropancreatic Neuroendocrine Neoplasm Pathobiology. PMID:28210673
MiR-30 Family Potentially Targeting PI3K-SIAH2 Predicted Interaction Network Represents a Novel Putative Theranostic Panel in Non-small Cell Lung Cancer. PMID:28210267
FocusHeuristics - expression-data-driven network optimization and disease gene prediction. PMID:28205611
Effect of myeloid differentiation primary response gene 88 on expression profiles of genes during the development and progression of Helicobacter-induced gastric cancer. PMID:28201999
Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1). PMID:28198434
Pharmacoinformatics, Adaptive Evolution, and Elucidation of Six Novel Compounds for Schizophrenia Treatment by Targeting DAOA (G72) Isoforms. PMID:28197415
Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing. PMID:28196478
Personalized Identification of Differentially Expressed Modules in Osteosarcoma. PMID:28190021
Time-resolved Phosphoproteome Analysis of Paradoxical RAF Activation Reveals Novel Targets of ERK. PMID:28188228
Doxycycline directly targets PAR1 to suppress tumor progression. PMID:28187433
Protein complex prediction for large protein protein interaction networks with the Core&Peel method. PMID:28185552
Prediction of biomarkers of oral squamous cell carcinoma using microarray technology. PMID:28176846
Molecular determinants of cytochrome C oxidase IV mRNA axonal trafficking. PMID:28161363
Uncovering stem cell differentiation factors for salivary gland regeneration by quantitative analysis of differential proteomes. PMID:28158262
TrypsNetDB: An integrated framework for the functional characterization of trypanosomatid proteins. PMID:28158179
Understanding cancer complexome using networks, spectral graph theory and multilayer framework. PMID:28155908
Cisplatin-Impaired Adipogenic Differentiation of Adipose Mesenchymal Stem Cells1. PMID:28155807
Prediction of Protein Interactions by Structural Matching: Prediction of PPI Networks and the Effects of Mutations on PPIs that Combines Sequence and Structural Information. PMID:28150242
An interactomics overview of the human and bovine milk proteome over lactation. PMID:28149201
Transcriptional responses to hyperplastic MRL signalling in Drosophila. PMID:28148822
The integration of weighted human gene association networks based on link prediction. PMID:28137253
Identification of the molecular mechanisms underlying dilated cardiomyopathy via bioinformatic analysis of gene expression profiles. PMID:28123501
Tensor Factorization for Precision Medicine in Heart Failure with Preserved Ejection Fraction. PMID:28116551
Adaptive Evolution of Extreme Acidophile Sulfobacillus thermosulfidooxidans Potentially Driven by Horizontal Gene Transfer and Gene Loss. PMID:28115381
Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks. PMID:28114351
Comparative Phosphoproteomics Reveals an Important Role of MKK2 in Banana (Musa spp.) Cold Signal Network. PMID:28106078
Identification of potential therapeutic targets for colorectal cancer by bioinformatics analysis. PMID:28105216
Genome-Wide Immune Modulation of TLR3-Mediated Inflammation in Intestinal Epithelial Cells Differs between Single and Multi-Strain Probiotic Combination. PMID:28099447
Expression and prognostic value of microRNAs in lower-grade glioma depends on IDH1/2 status. PMID:28091987
Gene-metabolite network analysis in different nonalcoholic fatty liver disease phenotypes. PMID:28082742
Transcriptional Regulatory Network Analysis for Gastric Cancer Based on mRNA Microarray. PMID:28078605
Repression of Fyn-related kinase in breast cancer cells is associated with promoter site-specific CpG methylation. PMID:28077797
RAIN: RNA-protein Association and Interaction Networks. PMID:28077569
Identifying a gene expression signature of cluster headache in blood. PMID:28074859
Context-sensitive network-based disease genetics prediction and its implications in drug discovery. PMID:28062449
Transcriptomic analysis of human norovirus NS1-2 protein highlights a multifunctional role in murine monocytes. PMID:28056773
Network-Based Approach to Identify Potential Targets and Drugs that Promote Neuroprotection and Neurorepair in Acute Ischemic Stroke. PMID:28054643
The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo. PMID:28026145
Selecting optimal combinations of transcription factors to promote axon regeneration: Why mechanisms matter. PMID:28025113
Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. PMID:28017472
Gene Turnover Contributes to the Evolutionary Adaptation of Acidithiobacillus caldus: Insights from Comparative Genomics. PMID:27999570
Cytological behaviour of floral organs and in silico characterization of differentially expressed transcript-derived fragments associated with 'floral bud distortion' in soybean. PMID:27994177
GENIUS: web server to predict local gene networks and key genes for biological functions. PMID:27993775
Identification of disease comorbidity through hidden molecular mechanisms. PMID:27991583
Phosphoproteomics of colon cancer metastasis: comparative mass spectrometric analysis of the isogenic primary and metastatic cell lines SW480 and SW620. PMID:27987026
Unraveling gene expression profiles in peripheral motor nerve from amyotrophic lateral sclerosis patients: insights into pathogenesis. PMID:27982123
Dual-seq transcriptomics reveals the battle for iron during Pseudomonas aeruginosa acute murine pneumonia. PMID:27982111
A pathway-centric view of spatial proximity in the 3D nucleome across cell lines. PMID:27976707
Analysis of Important Gene Ontology Terms and Biological Pathways Related to Pancreatic Cancer. PMID:27957501
Genetic study of congenital bile-duct dilatation identifies de novo and inherited variants in functionally related genes. PMID:27955658
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible. PMID:27924014
Identification of key genes induced by platelet-rich plasma in human dermal papilla cells using bioinformatics methods. PMID:27922680
Molecular mechanisms underlying the positive role of treadmill training in locomotor recovery after spinal cord injury. PMID:27922623
Evolutionary and Functional Features of Copy Number Variation in the Cattle Genome. PMID:27920798
Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians. PMID:27917918
Mining the Cicer arietinum genome for the mildew locus O (Mlo) gene family and comparative evolutionary analysis of the Mlo genes from Medicago truncatula and some other plant species. PMID:27900493
Quantitative label-free mass spectrometry analysis of formalin-fixed, paraffin-embedded tissue representing the invasive cutaneous malignant melanoma proteome. PMID:27899996
Gene-Based Genome-Wide Association Analysis in European and Asian Populations Identified Novel Genes for Rheumatoid Arthritis. PMID:27898717
DISCOVERY OF FUNCTIONAL AND DISEASE PATHWAYS BY COMMUNITY DETECTION IN PROTEIN-PROTEIN INTERACTION NETWORKS. PMID:27896987
Comparative analysis of gene expression profiles of gastric cardia adenocarcinoma and gastric non-cardia adenocarcinoma. PMID:27895742
Compact Integration of Multi-Network Topology for Functional Analysis of Genes. PMID:27889536
Measuring intratumor heterogeneity by network entropy using RNA-seq data. PMID:27883053
TP53 mutations, expression and interaction networks in human cancers. PMID:27880943
Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer. PMID:27876760
Computational approaches for the identification of cancer genes and pathways. PMID:27863091
RNAseq profiling of primary microglia and astrocyte cultures in near-term ovine fetus: A glial in vivo-in vitro multi-hit paradigm in large mammalian brain. PMID:27856275
Exploring Mouse Protein Function via Multiple Approaches. PMID:27846315
Small Regulatory RNAs of Rickettsia conorii. PMID:27834404
Proteomics profiling of interactome dynamics by colocalisation analysis (COLA). PMID:27824369
In silico identification of essential proteins in Corynebacterium pseudotuberculosis based on protein-protein interaction networks. PMID:27814699
Integrative analysis for identification of shared markers from various functional cells/tissues for rheumatoid arthritis. PMID:27812736
Neuroglobin, a Factor Playing for Nerve Cell Survival. PMID:27809238
A Novel Method for Pathway Identification Based on Attractor and Crosstalk in Polyarticular Juvenile Idiopathic Arthritis. PMID:27804927
Identification of crucial miRNAs and the targets in renal cortex of hypertensive patients by expression profiles. PMID:27802793
Global Dynamic Proteome Study of a Pellicle-forming Acinetobacter baumannii Strain. PMID:27799293
Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice. PMID:27799148
Identification of a RAI1-associated disease network through integration of exome sequencing, transcriptomics, and 3D genomics. PMID:27799067
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. PMID:27798618
Network-based analysis of omics data: the LEAN method. PMID:27797778
Molecular mechanisms underlying COPD-muscle dysfunction unveiled through a systems medicine approach. PMID:27794560
A computational interactome and functional annotation for the human proteome. PMID:27770567
Identification of potential candidate genes for hypertensive nephropathy based on gene expression profile. PMID:27756246
Advances in Sequencing Technologies for Understanding Hereditary Ataxias: A Review. PMID:27749953
Dynamic Phosphoproteome Analysis of Seedling Leaves in Brachypodium distachyon L. Reveals Central Phosphorylated Proteins Involved in the Drought Stress Response. PMID:27748408
Pathway Analysis Based on Attractor and Cross Talk in Colon Cancer. PMID:27746583
Expression profile and in silico characterization of novel RTF2h gene under oxidative stress in Indian catfish, Clarias magur (Hamilton 1822). PMID:27743114
Chromoplectic TPM3-ALK rearrangement in a patient with inflammatory myofibroblastic tumor who responded to ceritinib after progression on crizotinib. PMID:27742657
New Genes Involved in Osmotic Stress Tolerance in Saccharomyces cerevisiae. PMID:27733850
Ovarian transcriptomic study reveals the differential regulation of miRNAs and lncRNAs related to fecundity in different sheep. PMID:27731399
Staphylococcus epidermidis Biofilm-Released Cells Induce a Prompt and More Marked In vivo Inflammatory-Type Response than Planktonic or Biofilm Cells. PMID:27729907
Sequence Analysis of Hypothetical Proteins from Helicobacter pylori 26695 to Identify Potential Virulence Factors. PMID:27729842
Members of WRKY Group III transcription factors are important in TYLCV defense signaling pathway in tomato (Solanum lycopersicum). PMID:27717312
Microarray data analysis to identify crucial genes regulated by CEBPB in human SNB19 glioma cells. PMID:27716259
Potency Biomarker Signature Genes from Multiparametric Osteogenesis Assays: Will cGMP Human Bone Marrow Mesenchymal Stromal Cells Make Bone? PMID:27711115
Bioinformatics analysis of the molecular mechanism of diffuse intrinsic pontine glioma. PMID:27698822
Matrix metalloproteinase expression and molecular interaction network analysis in gastric cancer. PMID:27698806
Identification of genes involved in Epstein-Barr virus-associated nasopharyngeal carcinoma. PMID:27698802
Mechanism analysis of colorectal cancer according to the microRNA expression profile. PMID:27698796
Co-expressed differentially expressed genes and long non-coding RNAs involved in the celecoxib treatment of gastric cancer: An RNA sequencing analysis. PMID:27698747
Quantitative Proteomic and Phosphoproteomic Comparison of 2D and 3D Colon Cancer Cell Culture Models. PMID:27696853
Finding approximate gene clusters with Gecko 3. PMID:27679480
Classifying lower grade glioma cases according to whole genome gene expression. PMID:27677590
Global Phosphoproteomic Analysis Reveals the Involvement of Phosphorylation in Aflatoxins Biosynthesis in the Pathogenic Fungus Aspergillus flavus. PMID:27667718
Complex Patterns of Association between Pleiotropy and Transcription Factor Evolution. PMID:27635052
A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion. PMID:27627128
Constructing Bayesian networks by integrating gene expression and copy number data identifies NLGN4Y as a novel regulator of prostate cancer progression. PMID:27626693
An integrative study identifies KCNC2 as a novel predisposing factor for childhood obesity and the risk of diabetes in the Korean population. PMID:27623749
Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development. PMID:27621813
Quantitative Proteomic Analysis of Escherichia coli Heat-Labile Toxin B Subunit (LTB) with Enterovirus 71 (EV71) Subunit VP1. PMID:27618897
Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity. PMID:27611590
Analyzing and interpreting genome data at the network level with ConsensusPathDB. PMID:27606777
Candida albicans triggers the expression of inflammatory genes in human umbilical vein endothelial cells. PMID:27602073
Assessment of transfer methods for comparative genomics of regulatory networks in bacteria. PMID:27586594
Phenome-based gene discovery provides information about Parkinson's disease drug targets. PMID:27586503
Self-regulation of functional pathways by motifs inside the disordered tails of beta-catenin. PMID:27585692
Towards understanding brain-gut-microbiome connections in Alzheimer's disease. PMID:27585440
Discover the network underlying the connections between aging and age-related diseases. PMID:27582315
A PGC1α-mediated transcriptional axis suppresses melanoma metastasis. PMID:27580028
Predicting Diagnostic Gene Biomarkers for Non-Small-Cell Lung Cancer. PMID:27579312
A pathway-centric approach to rare variant association analysis. PMID:27577545
THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria. PMID:27571973
A genomics-based systems approach towards drug repositioning for rheumatoid arthritis. PMID:27557330
Ancient pathogen-driven adaptation triggers increased susceptibility to non-celiac wheat sensitivity in present-day European populations. PMID:27551316
STAMS: STRING-assisted module search for genome wide association studies and application to autism. PMID:27542772
Identification of compound-protein interactions through the analysis of gene ontology, KEGG enrichment for proteins and molecular fragments of compounds. PMID:27530612
VHLdb: A database of von Hippel-Lindau protein interactors and mutations. PMID:27511743
Transcriptomic Analysis of Staphylococcus epidermidis Biofilm-Released Cells upon Interaction with Human Blood Circulating Immune Cells and Soluble Factors. PMID:27493645
B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing. PMID:27487157
Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions. PMID:27482468
Identification of differentially expressed genes in salivary adenoid cystic carcinoma cells associated with metastasis. PMID:27478471
Metformin increases PDH and suppresses HIF-1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma. PMID:27474170
Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells. PMID:27464732
Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS. PMID:27460707
RichMind: A Tool for Improved Inference from Large-Scale Neuroimaging Results. PMID:27455041
A method for predicting protein complex in dynamic PPI networks. PMID:27454775
Meta-analysis of gene expression profiles identifies differential biomarkers for hepatocellular carcinoma and cholangiocarcinoma. PMID:27448818
Genome-wide analysis of DNA methylation in obese, lean, and miniature pig breeds. PMID:27444743
Cryptic protein-protein interaction motifs in the cytoplasmic domain of MHCI proteins. PMID:27435737
A Shortest-Path-Based Method for the Analysis and Prediction of Fruit-Related Genes in Arabidopsis thaliana. PMID:27434024
High-Throughput Small Interfering RNA Screening Identifies Phosphatidylinositol 3-Kinase Class II Alpha as Important for Production of Human Cytomegalovirus Virions. PMID:27412598
Identification of novel candidate drivers connecting different dysfunctional levels for lung adenocarcinoma using protein-protein interactions and a shortest path approach. PMID:27412431
Identification of candidate genes for myeloma-induced osteocyte death based on microarray data. PMID:27405725
Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens. PMID:27403523
Lithium-responsive genes and gene networks in bipolar disorder patient-derived lymphoblastoid cell lines. PMID:27401222
Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression. PMID:27388124
Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease. PMID:27381087
Gold nanorods inhibit respiratory syncytial virus by stimulating the innate immune response. PMID:27381068
Transcriptome- Assisted Label-Free Quantitative Proteomics Analysis Reveals Novel Insights into Piper nigrum-Phytophthora capsici Phytopathosystem. PMID:27379110
BcCluster: A Bladder Cancer Database at the Molecular Level. PMID:27376128
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins. PMID:27374120
Discovery Proteomics Identifies a Molecular Link between the Coatomer Protein Complex I and Androgen Receptor-dependent Transcription. PMID:27365400
A new strategy for exploring the hierarchical structure of cancers by adaptively partitioning functional modules from gene expression network. PMID:27349736
Isofunctional Protein Subfamily Detection Using Data Integration and Spectral Clustering. PMID:27348631
Investigation of potential molecular biomarkers and small molecule drugs for hepatocellular carcinoma transformed from cirrhosis. PMID:27347171
Integration and bioinformatics analysis of DNA-methylated genes associated with drug resistance in ovarian cancer. PMID:27347118
Regulatory mechanisms underlying sepsis progression in patients with tumor necrosis factor-α genetic variations. PMID:27347057
The "melanoma-enriched" microRNA miR-4731-5p acts as a tumour suppressor. PMID:27331623
A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma. PMID:27324824
Drosophila Torsin Protein Regulates Motor Control and Stress Sensitivity and Forms a Complex with Fragile-X Mental Retardation Protein. PMID:27313903
Notoginsenoside Rb1 inhibits activation of ERK and p38 MAPK pathways induced by hypoxia and hypercapnia. PMID:27313674
Web-based network analysis and visualization using CellMaps. PMID:27296979
System Review about Function Role of ESCC Driver Gene KDM6A by Network Biology Approach. PMID:27294188
Comprehensive coverage of cardiovascular disease data in the disease portals at the Rat Genome Database. PMID:27287925
Explaining the disease phenotype of intergenic SNP through predicted long range regulation. PMID:27280978
The Drosophila ETV5 Homologue Ets96B: Molecular Link between Obesity and Bipolar Disorder. PMID:27280443
NrdR Transcription Regulation: Global Proteome Analysis and Its Role in Escherichia coli Viability and Virulence. PMID:27275780
N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells. PMID:27267252
Prodrugs Bioactivated to Quinones Target NF-κB and Multiple Protein Networks: Identification of the Quinonome. PMID:27258437
Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu). PMID:27247549
The Use of Protein-Protein Interactions for the Analysis of the Associations between PM2.5 and Some Diseases. PMID:27243032
Chromosomal contacts connect loci associated with autism, BMI and head circumference phenotypes. PMID:27240531
The Prediction of Key Cytoskeleton Components Involved in Glomerular Diseases Based on a Protein-Protein Interaction Network. PMID:27227331
Stage-specific Proteomes from Onchocerca ochengi, Sister Species of the Human River Blindness Parasite, Uncover Adaptations to a Nodular Lifestyle. PMID:27226403
A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection. PMID:27226375
Understanding the dimorphic lifestyles of human gastric pathogen Helicobacter pylori using the SWATH-based proteomics approach. PMID:27222005
Integrated Analysis of Expression Profile Based on Differentially Expressed Genes in Middle Cerebral Artery Occlusion Animal Models. PMID:27213359
A flexible method for estimating the fraction of fitness influencing mutations from large sequencing data sets. PMID:27197222
Practical aspects of NGS-based pathways analysis for personalized cancer science and medicine. PMID:27191992
The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease. PMID:27189168
Identifying a biomarker network for corticosteroid resistance in asthma from bronchoalveolar lavage samples. PMID:27188427
A systems biology pipeline identifies new immune and disease related molecular signatures and networks in human cells during microgravity exposure. PMID:27185415
Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9. PMID:27182943
Phosphoprotein network analysis of white adipose tissues unveils deregulated pathways in response to high-fat diet. PMID:27180971
Low expression of leptin and its association with breast cancer: A transcriptomic study. PMID:27177292
The Clathrin-dependent Spindle Proteome. PMID:27174698
Co-expression network-based analysis of hippocampal expression data associated with Alzheimer's disease using a novel algorithm. PMID:27168792
Translationally controlled tumour protein (TCTP) from tomato and Nicotiana benthamiana is necessary for successful infection by a potyvirus. PMID:27159273
Laminin-binding integrin gene copy number alterations in distinct epithelial-type cancers. PMID:27158381
Quantitative proteomics and integrative network analysis identified novel genes and pathways related to osteoporosis. PMID:27153759
DrugGenEx-Net: a novel computational platform for systems pharmacology and gene expression-based drug repurposing. PMID:27151405
Identification of breast cancer candidate genes using gene co-expression and protein-protein interaction information. PMID:27150055
How Hepatitis C Virus Leads to Hepatocellular Carcinoma: A Network-Based Study. PMID:27148389
K-shell Analysis Reveals Distinct Functional Parts in an Electron Transfer Network and Its Implications for Extracellular Electron Transfer. PMID:27148219
Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking. PMID:27136326
Associations between joint effusion in the knee and gene expression levels in the circulation: a meta-analysis. PMID:27134727
BioTapestry now provides a web application and improved drawing and layout tools. PMID:27134726
A Protein Domain and Family Based Approach to Rare Variant Association Analysis. PMID:27128313
The healthy human microbiome. PMID:27122046
PTIR: Predicted Tomato Interactome Resource. PMID:27121261
CoReCG: a comprehensive database of genes associated with colon-rectal cancer. PMID:27114494
Standardized Profiling of The Membrane-Enriched Proteome of Mouse Dorsal Root Ganglia (DRG) Provides Novel Insights Into Chronic Pain. PMID:27103637
The interactome of Streptococcus pneumoniae and its bacteriophages show highly specific patterns of interactions among bacteria and their phages. PMID:27103053
Protein-protein interaction network analysis of cirrhosis liver disease. PMID:27099671
Quantitative Tagless Copurification: A Method to Validate and Identify Protein-Protein Interactions. PMID:27099342
Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package. PMID:27096930
Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance. PMID:27095270
Identification of Bovine Sperm Surface Proteins Involved in Carbohydrate-mediated Fertilization Interactions. PMID:27094474
APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone. PMID:27092780
Application of wide selected-ion monitoring data-independent acquisition to identify tomato fruit proteins regulated by the CUTIN DEFICIENT2 transcription factor. PMID:27089858
Comparison of molecular mechanisms of rheumatoid arthritis and osteoarthritis using gene microarrays. PMID:27082252
Proteomic differences between native and tissue-engineered tendon and ligament. PMID:27080496
Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer. PMID:27078000
STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia. PMID:27074565
Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea. PMID:27070092
A Quantitative Approach to Analyzing Genome Reductive Evolution Using Protein-Protein Interaction Networks: A Case Study of Mycobacterium leprae. PMID:27066064
Characterization of the direct targets of FOXO transcription factors throughout evolution. PMID:27061590
Stress chaperone mortalin regulates human melanogenesis. PMID:27056733
Lysophosphatidic Acid Receptor Is a Functional Marker of Adult Hippocampal Precursor Cells. PMID:27050949
ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation. PMID:27050377
A Novel Prioritization Method in Identifying Recurrent Venous Thromboembolism-Related Genes. PMID:27050193
Identification and Comparative Analysis of H2O2-Scavenging Enzymes (Ascorbate Peroxidase and Glutathione Peroxidase) in Selected Plants Employing Bioinformatics Approaches. PMID:27047498
Mechanistically linked serum miRNAs distinguish between drug induced and fatty liver disease of different grades. PMID:27045805
Screening for genes and subnetworks associated with pancreatic cancer based on the gene expression profile. PMID:27035224
Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine. PMID:27032388
Metabolism-related enzyme alterations identified by proteomic analysis in human renal cell carcinoma. PMID:27022288
Genomic, Lipidomic and Metabolomic Analysis of Cyclooxygenase-null Cells: Eicosanoid Storm, Cross Talk, and Compensation by COX-1. PMID:27012456
Identification of a dTDP-rhamnose biosynthetic pathway that oscillates with the molting cycle in Caenorhabditis elegans. PMID:27009306
Role of MicroRNAs in carcinogenesis that potential for biomarker of endometrial cancer. PMID:27006767
Pathway analysis in attention deficit hyperactivity disorder: An ensemble approach. PMID:27004716
Integration of Metabolic Modeling with Gene Co-expression Reveals Transcriptionally Programmed Reactions Explaining Robustness in Mycobacterium tuberculosis. PMID:27000948
Expression profile analysis based on DNA microarray for patients undergoing off-pump coronary artery bypass surgery. PMID:26998004
Xp22.33p22.12 Duplication in a Patient with Intellectual Disability and Dysmorphic Facial Features. PMID:26997944
A Protein Complex Map of Trypanosoma brucei. PMID:26991453
CSCdb: a cancer stem cells portal for markers, related genes and functional information. PMID:26989154
Understanding butanol tolerance and assimilation in Pseudomonas putida BIRD-1: an integrated omics approach. PMID:26986205
Epigenetic Studies Point to DNA Replication/Repair Genes as a Basis for the Heritable Nature of Long Term Complications in Diabetes. PMID:26981540
Protein Kinase A Activation Promotes Cancer Cell Resistance to Glucose Starvation and Anoikis. PMID:26978032
Detailed phenotyping identifies genes with pleiotropic effects on body composition. PMID:26968377
Comparative analysis of genome-wide Mlo gene family in Cajanus cajan and Phaseolus vulgaris. PMID:26961357
IL-22 Impedes the Proliferation of Schwann cells: Transcriptome Sequencing and Bioinformatics Analysis. PMID:26960328
The Impact of Mass Spectrometry-Based Proteomics on Fundamental Discoveries in Virology. PMID:26958735
Combining Human Disease Genetics and Mouse Model Phenotypes towards Drug Repositioning for Parkinson's disease. PMID:26958284
DenguePredict: An Integrated Drug Repositioning Approach towards Drug Discovery for Dengue. PMID:26958268
Two overlapping two-component systems in Xanthomonas oryzae pv. oryzae contribute to full fitness in rice by regulating virulence factors expression. PMID:26957113
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines. PMID:26947069
Interaction between inflammatory mediators and miRNAs in Helicobacter pylori infection. PMID:26945693
Identification of biological targets of therapeutic intervention for clear cell renal cell carcinoma based on bioinformatics approach. PMID:26941587
Involvement of Polycomb Repressive Complex 2 in Maturation of Induced Pluripotent Stem Cells during Reprogramming of Mouse and Human Fibroblasts. PMID:26938987
Integrated microRNA‑gene analysis of coronary artery disease based on miRNA and gene expression profiles. PMID:26936111
Premature termination codons in modern human genomes. PMID:26932450
A Multi-Method Approach for Proteomic Network Inference in 11 Human Cancers. PMID:26928298
Key Immune Events of the Pathomechanisms of Early Cardioembolic Stroke: Multi-Database Mining and Systems Biology Approach. PMID:26927091
Genomics of Rapid Incipient Speciation in Sympatric Threespine Stickleback. PMID:26925837
Analysis of transcripts differentially expressed between fruited and deflowered 'Gala' adult trees: a contribution to biennial bearing understanding in apple. PMID:26924309
Cloning, expression, purification, crystallization and X-ray crystallographic analysis of recombinant human C1ORF123 protein. PMID:26919524
Spatial colocalization and functional link of purinosomes with mitochondria. PMID:26912862
Reduced-representation Phosphosignatures Measured by Quantitative Targeted MS Capture Cellular States and Enable Large-scale Comparison of Drug-induced Phenotypes. PMID:26912667
Data detailing the platelet acetyl-lysine proteome. PMID:26904711
Genomic Analysis of the Human Gut Microbiome Suggests Novel Enzymes Involved in Quinone Biosynthesis. PMID:26904004
A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program. PMID:26898779
Identification of genes and pathways associated with pancreatic ductal adenocarcinoma by bioinformatics analyses. PMID:26893748
Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum. PMID:26893683
Revealing the role of VEGFA in clear cell sarcoma of the kidney by protein-protein interaction network and significant pathway analysis. PMID:26893674
Antibiotic binding of STY3178, a yfdX protein from Salmonella Typhi. PMID:26892637
Exome sequencing reveals genetic differentiation due to high-altitude adaptation in the Tibetan cashmere goat (Capra hircus). PMID:26892324
Proteome Based Construction of the Lymphocyte Function-Associated Antigen 1 (LFA-1) Interactome in Human Dendritic Cells. PMID:26889827
Transcriptomic Profiling of Extracellular RNAs Present in Cerebrospinal Fluid Identifies Differentially Expressed Transcripts in Parkinson's Disease. PMID:26889637
The non-Geldanamycin Hsp90 inhibitors enhanced the antifungal activity of fluconazole. PMID:26885259
Phi Class of Glutathione S-transferase Gene Superfamily Widely Exists in Nonplant Taxonomic Groups. PMID:26884677
Cross-platform comparison of independent datasets identifies an immune signature associated with improved survival in metastatic melanoma. PMID:26883106
Label-Free Proteomic Analysis of Flavohemoglobin Deleted Strain of Saccharomyces cerevisiae. PMID:26881076
In silico analysis of Mn transporters (NRAMP1) in various plant species. PMID:26878855
Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors. PMID:26877223
Identification of potential therapeutic targets for papillary thyroid carcinoma by bioinformatics analysis. PMID:26870166
Regulation of WRKY46 Transcription Factor Function by Mitogen-Activated Protein Kinases in Arabidopsis thaliana. PMID:26870073
Identification of candidate genes involved in Witches' broom disease resistance in a segregating mapping population of Theobroma cacao L. in Brazil. PMID:26865216
The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation. PMID:26859351
An Impaired Respiratory Electron Chain Triggers Down-regulation of the Energy Metabolism and De-ubiquitination of Solute Carrier Amino Acid Transporters. PMID:26852163
Bridging semantics and syntax with graph algorithms-state-of-the-art of extracting biomedical relations. PMID:26851224
Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations. PMID:26850065
An integrated in silico approach for functional and structural impact of non- synonymous SNPs in the MYH1 gene in Jeju Native Pigs. PMID:26847462
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability. PMID:26842758
Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition. PMID:26842662
Predicting Long Noncoding RNA and Protein Interactions Using Heterogeneous Network Model. PMID:26839884
Network-based in silico drug efficacy screening. PMID:26831545
In silico analyses of heparin binding proteins expression in human periodontal tissues. PMID:26821679
Gene expression profiling identifies candidate biomarkers for active and latent tuberculosis. PMID:26818387
Active medulloblastoma enhancers reveal subgroup-specific cellular origins. PMID:26814967
Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite. PMID:26813983
Bioinformatics analysis of hepatitis C virus genotype 2a-induced human hepatocellular carcinoma in Huh7 cells. PMID:26811688
Application of computational methods in genetic study of inflammatory bowel disease. PMID:26811639
Meta-Analyses of Microarray Datasets Identifies ANO1 and FADD as Prognostic Markers of Head and Neck Cancer. PMID:26808319
Analysis of Protein-protein Interaction Interface between Yeast Mitochondrial Proteins Rim1 and Pif1 Using Chemical Cross-linking Mass Spectrometry. PMID:26807012
H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs. PMID:26804911
Operon Gene Order Is Optimized for Ordered Protein Complex Assembly. PMID:26804901
Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. PMID:26801178
The biochemical and mass spectrometric profiling of the dystrophin complexome from skeletal muscle. PMID:26793286
Protein Sequence Annotation Tool (PSAT): a centralized web-based meta-server for high-throughput sequence annotations. PMID:26792120
Predicting chemotherapeutic drug combinations through gene network profiling. PMID:26791325
Metagenome-scale analysis yields insights into the structure and function of microbial communities in a copper bioleaching heap. PMID:26781463
A predictive computational framework for direct reprogramming between human cell types. PMID:26780608
Decoding Cellular Dynamics in Epidermal Growth Factor Signaling Using a New Pathway-Based Integration Approach for Proteomics and Transcriptomics Data. PMID:26779252
Expression of aurora kinase A correlates with the Wnt-modulator RACGAP1 in gastric cancer. PMID:26778597
COMPUTING THERAPY FOR PRECISION MEDICINE: COLLABORATIVE FILTERING INTEGRATES AND PREDICTS MULTI-ENTITY INTERACTIONS. PMID:26776170
Integrative meta-analysis identifies microRNA-regulated networks in infantile hemangioma. PMID:26772808
Analysis of differentially expressed genes based on microarray data of glioma. PMID:26770324
Sensing of latent EBV infection through exosomal transfer of 5'pppRNA. PMID:26768848
Analysis of the Protein Kinase A-Regulated Proteome of Cryptococcus neoformans Identifies a Role for the Ubiquitin-Proteasome Pathway in Capsule Formation. PMID:26758180
A draft map of the mouse pluripotent stem cell spatial proteome. PMID:26754106
Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster. PMID:26751788
LEGO: a novel method for gene set over-representation analysis by incorporating network-based gene weights. PMID:26750448
Gene Duplicability of Core Genes Is Highly Consistent across All Angiosperms. PMID:26744215
Identification of novel gene and pathway targets for human epilepsy treatment. PMID:26742644
Identification of potential therapeutic targets for lung cancer by bioinformatics analysis. PMID:26739332
A Zinc-Dependent Protease AMZ-tk from a Thermophilic Archaeon is a New Member of the Archaemetzincin Protein Family. PMID:26733945
Path2PPI: an R package to predict protein-protein interaction networks for a set of proteins. PMID:26733452
Altered expression of mRNA profiles in blood of early-onset schizophrenia. PMID:26733343
BioGRID: A Resource for Studying Biological Interactions in Yeast. PMID:26729913
Identifying novel protein phenotype annotations by hybridizing protein-protein interactions and protein sequence similarities. PMID:26728152
Blood-based gene expression signatures of medication-free outpatients with major depressive disorder: integrative genome-wide and candidate gene analyses. PMID:26728011
The interactive association between heat shock factor 1 and heat shock proteins in primary myocardial cells subjected to heat stress. PMID:26719858
Role of NSC319726 in ovarian cancer based on the bioinformatics analyses. PMID:26719703
Brain Transcriptomic Response to Social Eavesdropping in Zebrafish (Danio rerio). PMID:26713440
Prediction of the anti-inflammatory mechanisms of curcumin by module-based protein interaction network analysis. PMID:26713275
AraC-Type Regulator Rsp Adapts Staphylococcus aureus Gene Expression to Acute Infection. PMID:26712209
Unravelling druggable signalling networks that control F508del-CFTR proteostasis. PMID:26701908
Forward Individualized Medicine from Personal Genomes to Interactomes. PMID:26696898
Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain. PMID:26693857
LENS: web-based lens for enrichment and network studies of human proteins. PMID:26680011
Screening of potential biomarkers for cholangiocarcinoma by integrated analysis of microarray data sets. PMID:26679756
YAGM: a web tool for mining associated genes in yeast based on diverse biological associations. PMID:26678566
Taking Bioinformatics to Systems Medicine. PMID:26677177
Integrated Genomic Analysis of Pancreatic Ductal Adenocarcinomas Reveals Genomic Rearrangement Events as Significant Drivers of Disease. PMID:26676757
Transferrin-bound proteins as potential biomarkers for advanced breast cancer patients. PMID:26673961
Proteogenomics from a bioinformatics angle: A growing field. PMID:26670565
IRES-dependent translated genes in fungi: computational prediction, phylogenetic conservation and functional association. PMID:26666532
A Comparison of the Chicken and Turkey Proteomes and Phosphoproteomes in the Development of Poultry-Specific Immuno-Metabolism Kinome Peptide Arrays. PMID:26664921
Correlating chemical sensitivity and basal gene expression reveals mechanism of action. PMID:26656090
Proteome Analysis of Renoprotection Mediated by a Novel Cyclic Helix B Peptide in Acute Kidney Injury. PMID:26655840
Muscle Expression of SOD1(G93A) Modulates microRNA and mRNA Transcription Pattern Associated with the Myelination Process in the Spinal Cord of Transgenic Mice. PMID:26648847
Identification of Major Signaling Pathways in Prion Disease Progression Using Network Analysis. PMID:26646948
Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort. PMID:26643968
Identification of Drosophila Zfh2 as a Mediator of Hypercapnic Immune Regulation by a Genome-Wide RNA Interference Screen. PMID:26643480
Transcriptome and Molecular Endocrinology Aspects of Epicardial Adipose Tissue in Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Observational Studies. PMID:26636103
Proteomic Analysis Reveals Key Proteins and Phosphoproteins upon Seed Germination of Wheat (Triticum aestivum L.). PMID:26635843
Screening of potential biomarkers for chemoresistant ovarian carcinoma with miRNA expression profiling data by bioinformatics approach. PMID:26622864
Prediction and Characterisation of the System Effects of Aristolochic Acid: A Novel Joint Network Analysis towards Therapeutic and Toxicological Mechanisms. PMID:26620132
Drug target prioritization by perturbed gene expression and network information. PMID:26615774
An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes. PMID:26609137
Exploring Transcription Factors-microRNAs Co-regulation Networks in Schizophrenia. PMID:26609121
Changes in the enhancer landscape during early placental development uncover a trophoblast invasion gene-enhancer network. PMID:26604129
From Single Variants to Protein Cascades: MULTISCALE MODELING OF SINGLE NUCLEOTIDE VARIANT SETS IN GENETIC DISORDERS. PMID:26601959
Deciphering the molecular adaptation of the king scallop (Pecten maximus) to heat stress using transcriptomics and proteomics. PMID:26596422
NDEx, the Network Data Exchange. PMID:26594663
STITCH 5: augmenting protein-chemical interaction networks with tissue and affinity data. PMID:26590256
Computing interaction probabilities in signaling networks. PMID:26587014
Proteomic analysis of tylosin-resistant Mycoplasma gallisepticum reveals enzymatic activities associated with resistance. PMID:26584633
Experimental detection of short regulatory motifs in eukaryotic proteins: tips for good practice as well as for bad. PMID:26581338
Cellular reprogramming through mitogen-activated protein kinases. PMID:26579181
Unexpected features of the dark proteome. PMID:26578815
Hydroxyproline O-arabinosyltransferase mutants oppositely alter tip growth in Arabidopsis thaliana and Physcomitrella patens. PMID:26577059
A method for developing regulatory gene set networks to characterize complex biological systems. PMID:26576648
Uncovering Phosphorylation-Based Specificities through Functional Interaction Networks. PMID:26572964
CentiServer: A Comprehensive Resource, Web-Based Application and R Package for Centrality Analysis. PMID:26571275
Genome-wide Screening of Regulators of Catalase Expression: ROLE OF A TRANSCRIPTION COMPLEX AND HISTONE AND tRNA MODIFICATION COMPLEXES ON ADAPTATION TO STRESS. PMID:26567340
Bringing Down Cancer Aircraft: Searching for Essential Hypomutated Proteins in Skin Melanoma. PMID:26565620
Next-generation diagnostics and disease-gene discovery with the Exomiser. PMID:26562621
Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency. PMID:26562225
Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms. PMID:26559926
Potential Role of lncRNAs in Contributing to Pathogenesis of Intervertebral Disc Degeneration Based on Microarray Data. PMID:26556537
Sieve-based relation extraction of gene regulatory networks from biological literature. PMID:26551454
Screening feature genes of lung carcinoma with DNA microarray analysis. PMID:26550126
Host-Microbe Protein Interactions during Bacterial Infection. PMID:26548613
5p13.3p13.2 duplication associated with developmental delay, congenital malformations and chromosome instability manifested as low-level aneuploidy. PMID:26543751
DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes. PMID:26541172
PPCM: Combing Multiple Classifiers to Improve Protein-Protein Interaction Prediction. PMID:26539460
BRANE Cut: biologically-related a priori network enhancement with graph cuts for gene regulatory network inference. PMID:26537179
Comparative Genome of GK and Wistar Rats Reveals Genetic Basis of Type 2 Diabetes. PMID:26529237
Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology. PMID:26519433
Network analysis of gene essentiality in functional genomics experiments. PMID:26518695
Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer's disease: identification of common and distinct olfactory targets across Alzheimer-related co-pathologies. PMID:26517091
Epigenetics and Preeclampsia: Defining Functional Epimutations in the Preeclamptic Placenta Related to the TGF-β Pathway. PMID:26510177
A Molecular-Level Landscape of Diet-Gut Microbiome Interactions: Toward Dietary Interventions Targeting Bacterial Genes. PMID:26507230
Sarcosine Catabolism in Pseudomonas aeruginosa Is Transcriptionally Regulated by SouR. PMID:26503852
Deciphering the mode of action of a mutant Allium sativum Leaf Agglutinin (mASAL), a potent antifungal protein on Rhizoctonia solani. PMID:26502719
Roles of Nucleoid-Associated Proteins in Stress-Induced Mutagenic Break Repair in Starving Escherichia coli. PMID:26500258
Integrated analysis of miRNA and mRNA paired expression profiling of prenatal skeletal muscle development in three genotype pigs. PMID:26496978
Methods for biological data integration: perspectives and challenges. PMID:26490630
A functional module-based exploration between inflammation and cancer in esophagus. PMID:26489668
Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia. PMID:26485648
A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces. PMID:26485003
Systems Biology for Smart Crops and Agricultural Innovation: Filling the Gaps between Genotype and Phenotype for Complex Traits Linked with Robust Agricultural Productivity and Sustainability. PMID:26484978
Protein Analysis of Sapienic Acid-Treated Porphyromonas gingivalis Suggests Differential Regulation of Multiple Metabolic Pathways. PMID:26483519
Cyclosporin A induced toxicity in mouse liver slices is only slightly aggravated by Fxr-deficiency and co-occurs with upregulation of pro-inflammatory genes and downregulation of genes involved in mitochondrial functions. PMID:26482353
The SIDER database of drugs and side effects. PMID:26481350
Characterization of the hypothalamic transcriptome in response to food deprivation reveals global changes in long noncoding RNA, and cell cycle response genes. PMID:26475716
Improved detection of disease-associated variation by sex-specific characterization and prediction of genes required for fertility. PMID:26473511
Cellular Signature of SIL1 Depletion: Disease Pathogenesis due to Alterations in Protein Composition Beyond the ER Machinery. PMID:26468156
Gene Prioritization by Compressive Data Fusion and Chaining. PMID:26465776
Comparison of the protein-coding gene content of Chlamydia trachomatis and Protochlamydia amoebophila using a Raspberry Pi computer. PMID:26462790
Revealing potential molecular targets bridging colitis and colorectal cancer based on multidimensional integration strategy. PMID:26461477
Gene expression profile analysis of ventilator-associated pneumonia. PMID:26459786
Evolutionary rescue by compensatory mutations is constrained by genomic and environmental backgrounds. PMID:26459777
MicroRNA-derived network analysis of differentially methylated genes in schizophrenia, implicating GABA receptor B1 [GABBR1] and protein kinase B [AKT1]. PMID:26450699
Integrated genome-wide analysis of genomic changes and gene regulation in human adrenocortical tissue samples. PMID:26446994
Genome-Wide Gene Expression Analysis Identifies the Proto-oncogene Tyrosine-Protein Kinase Src as a Crucial Virulence Determinant of Infectious Laryngotracheitis Virus in Chicken Cells. PMID:26446601
Bioinformatics analyses of differentially expressed genes associated with bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma. PMID:26445550
A survey about methods dedicated to epistasis detection. PMID:26442103
A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling. PMID:26438848
Systematic analysis of somatic mutations impacting gene expression in 12 tumour types. PMID:26436532
Synergistic Gene Expression Signature Observed in TK6 Cells upon Co-Exposure to UVC-Irradiation and Protein Kinase C-Activating Tumor Promoters. PMID:26431317
Dynamics in Transcriptomics: Advancements in RNA-seq Time Course and Downstream Analysis. PMID:26430493
RegNetwork: an integrated database of transcriptional and post-transcriptional regulatory networks in human and mouse. PMID:26424082
Hypoxia Strongly Affects Mitochondrial Ribosomal Proteins and Translocases, as Shown by Quantitative Proteomics of HeLa Cells. PMID:26421188
The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence. PMID:26416763
Integrative analyses reveal transcriptome-proteome correlation in biological pathways and secondary metabolism clusters in A. flavus in response to temperature. PMID:26416011
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera. PMID:26415554
Identification of Circulating Biomarker Candidates for Hepatocellular Carcinoma (HCC): An Integrated Prioritization Approach. PMID:26414287
miRTex: A Text Mining System for miRNA-Gene Relation Extraction. PMID:26407127
Graph theoretic network analysis reveals protein pathways underlying cell death following neurotropic viral infection. PMID:26404759
Recent findings and technological advances in phosphoproteomics for cells and tissues. PMID:26400465
High-Throughput Identification of Cis-Regulatory Rewiring Events in Yeast. PMID:26399482
Proteome-wide quantitative multiplexed profiling of protein expression: carbon-source dependency in Saccharomyces cerevisiae. PMID:26399295
The Relationship of Immune Cell Signatures to Patient Survival Varies within and between Tumor Types. PMID:26398410
Protein networks in induced sputum from smokers and COPD patients. PMID:26396508
Transcriptome Sequencing to Identify Transcription Factor Regulatory Network and Alternative Splicing in Endothelial Cells Under VEGF Stimulation. PMID:26395122
Proteomic Analyses for the Global S-Nitrosylated Proteins in the Brain Tissues of Different Human Prion Diseases. PMID:26392294
The outer mucus layer hosts a distinct intestinal microbial niche. PMID:26392213
Metabolome and proteome changes with aging in Caenorhabditis elegans. PMID:26390854
Global transcriptome and mutagenic analyses of the acid tolerance response of Salmonella enterica serovar Typhimurium. PMID:26386064
SimiRa: A tool to identify coregulation between microRNAs and RNA-binding proteins. PMID:26383775
The Mechanism Research of Qishen Yiqi Formula by Module-Network Analysis. PMID:26379745
Comparative proteomic analysis of a membrane-enriched fraction from flag leaves reveals responses to chemical hybridization agent SQ-1 in wheat. PMID:26379693
Phosphoproteomic analysis reveals Smarcb1 dependent EGFR signaling in Malignant Rhabdoid tumor cells. PMID:26370283
LncReg: a reference resource for lncRNA-associated regulatory networks. PMID:26363021
Inhibition of elongin C promotes longevity and protein homeostasis via HIF-1 in C. elegans. PMID:26361075
Proteomic analysis of embryonic kidney development: Heterochromatin proteins as epigenetic regulators of nephrogenesis. PMID:26359909
Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data. PMID:26354681
Integrated Analyses of Gene Expression Profiles Digs out Common Markers for Rheumatic Diseases. PMID:26352601
Discovery of Intermediary Genes between Pathways Using Sparse Regression. PMID:26348038
Panorama of ancient metazoan macromolecular complexes. PMID:26344197
Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. PMID:26339636
SwissPalm: Protein Palmitoylation database. PMID:26339475
Large-scale extraction of gene interactions from full-text literature using DeepDive. PMID:26338771
Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis. PMID:26336360
Genes related to inflammation and bone loss process in periodontitis suggested by bioinformatics methods. PMID:26334995
Integration of 'omics' data in aging research: from biomarkers to systems biology. PMID:26331998
Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types. PMID:26330083
The Identification of Genes Important in Pseudomonas syringae pv. phaseolicola Plant Colonisation Using In Vitro Screening of Transposon Libraries. PMID:26325299
Susceptibility Genes for Multiple Sclerosis Identified in a Gene-Based Genome-Wide Association Study. PMID:26320842
A core of kinase-regulated interactomes defines the neoplastic MDSC lineage. PMID:26320174
Family Wide Molecular Adaptations to Underground Life in African Mole-Rats Revealed by Phylogenomic Analysis. PMID:26318402
Of Fighting Flies, Mice, and Men: Are Some of the Molecular and Neuronal Mechanisms of Aggression Universal in the Animal Kingdom? PMID:26312756
A Rich-Club Organization in Brain Ischemia Protein Interaction Network. PMID:26310627
Transcriptome-wide identification of Camellia sinensis WRKY transcription factors in response to temperature stress. PMID:26308611
Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin. PMID:26307164
Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes. PMID:26307061
RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states. PMID:26305935
Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations. PMID:26304112
Selective enrichment of mycobacterial proteins from infected host macrophages. PMID:26303024
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. PMID:26301688
Coxiella burnetii and Leishmania mexicana residing within similar parasitophorous vacuoles elicit disparate host responses. PMID:26300862
Fetal microglial phenotype in vitro carries memory of prior in vivo exposure to inflammation. PMID:26300730
Gene-expression and in vitro function of mesenchymal stromal cells are affected in juvenile myelomonocytic leukemia. PMID:26294732
CNV Analysis Associates AKNAD1 with Type-2 Diabetes in Jordan Subpopulations. PMID:26292654
Functional characterization of drought-responsive modules and genes in Oryza sativa: a network-based approach. PMID:26284112
A PAS domain-containing regulator controls flagella-flagella interactions in Campylobacter jejuni. PMID:26284050
Gene scanning and heart attack risk. PMID:26277204
Integrative network-based analysis of mRNA and microRNA expression in 1,25-dihydroxyvitamin D3-treated cancer cells. PMID:26276506
An Association Rule Mining Approach to Discover lncRNAs Expression Patterns in Cancer Datasets. PMID:26273587
Potential anti-cancer effect of curcumin in human lung squamous cell carcinoma. PMID:26273408
Distilling a Visual Network of Retinitis Pigmentosa Gene-Protein Interactions to Uncover New Disease Candidates. PMID:26267445
Dissecting ancestry genomic background in substance dependence genome-wide association studies. PMID:26267224
Spt-Ada-Gcn5-Acetyltransferase (SAGA) Complex in Plants: Genome Wide Identification, Evolutionary Conservation and Functional Determination. PMID:26263547
Computational analysis of protein interaction networks for infectious diseases. PMID:26261187
Lysine acetyltransfer supports platelet function. PMID:26256950
A proteomic profile of synoviocyte lesions microdissected from formalin-fixed paraffin-embedded synovial tissues of rheumatoid arthritis. PMID:26251654
Remote Ischemic Conditioning Alters Methylation and Expression of Cell Cycle Genes in Aneurysmal Subarachnoid Hemorrhage. PMID:26251247
Transcriptome analysis provides insights into the regulatory function of alternative splicing in antiviral immunity in grass carp (Ctenopharyngodon idella). PMID:26248502
Quantitative proteomics analysis of an ethanol- and a lactate-producing mutant strain of Synechocystis sp. PCC6803. PMID:26246854
Network analysis reveals a stress-affected common gene module among seven stress-related diseases/systems which provides potential targets for mechanism research. PMID:26245528
A Novel Role of Numb as A Regulator of Pro-inflammatory Cytokine Production in Macrophages in Response to Toll-like Receptor 4. PMID:26244698
In-depth analysis of the critical genes and pathways in colorectal cancer. PMID:26239303
Functional analysis of the nasopharyngeal carcinoma primary tumor‑associated gene interaction network. PMID:26238040
Prediction of problematic complexes from PPI networks: sparse, embedded, and small complexes. PMID:26231465
Identification of the key genes connected with plasma cells of multiple myeloma using expression profiles. PMID:26229487
Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Macrophage Colony Stimulating Factor (M-CSF) Grown Macrophages Derived from Murine Bone Marrow Cells. PMID:26229149
Conserved and divergent functions of RcrRPQ in Streptococcus gordonii and S. mutans. PMID:26229070
RNAseq analysis of fast skeletal muscle in restriction-fed transgenic coho salmon (Oncorhynchus kisutch): an experimental model uncoupling the growth hormone and nutritional signals regulating growth. PMID:26228074
Cancer type-dependent genetic interactions between cancer driver alterations indicate plasticity of epistasis across cell types. PMID:26227665
Identification of Subtype-Specific Prognostic Genes for Early-Stage Lung Adenocarcinoma and Squamous Cell Carcinoma Patients Using an Embedded Feature Selection Algorithm. PMID:26226392
Distinct Responses of Mycobacterium smegmatis to Exposure to Low and High Levels of Hydrogen Peroxide. PMID:26225431
Effects of β-catenin on differentially expressed genes in multiple myeloma. PMID:26223925
Biological processes and pathway changes in isoflurane-induced anesthesia revealed by bioinformatics analysis of gene expression profiles. PMID:26223573
Screening feature genes of osteosarcoma with DNA microarray: a bioinformatic analysis. PMID:26221251
Family-based analysis of eight susceptibility loci in polycystic ovary syndrome. PMID:26220222
Functional Networks of Highest-Connected Splice Isoforms: From The Chromosome 17 Human Proteome Project. PMID:26216192
Massive interstitial copy-neutral loss-of-heterozygosity as evidence for cancer being a disease of the DNA-damage response. PMID:26208496
Microarray Analysis of the Major Depressive Disorder mRNA Profile Data. PMID:26207134
Identification of a multi-cancer gene expression biomarker for cancer clinical outcomes using a network-based algorithm. PMID:26202601
Associations of SNPs located at candidate genes to bovine growth traits, prioritized with an interaction networks construction approach. PMID:26198337
A draft network of ligand-receptor-mediated multicellular signalling in human. PMID:26198319
Genome Wide Re-Annotation of Caldicellulosiruptor saccharolyticus with New Insights into Genes Involved in Biomass Degradation and Hydrogen Production. PMID:26196387
Identification of prostate cancer biomarkers in urinary exosomes. PMID:26196085
Deep Sequencing Analysis of miRNA Expression in Breast Muscle of Fast-Growing and Slow-Growing Broilers. PMID:26193261
Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS. PMID:26192745
Screening of potential target genes for cataract by analyzing mRNA expression profile of mouse Hsf4-null lens. PMID:26187041
Elucidating Compound Mechanism of Action by Network Perturbation Analysis. PMID:26186195
The BioPlex Network: A Systematic Exploration of the Human Interactome. PMID:26186194
An integrative approach to analyze microarray datasets for prioritization of genes relevant to lens biology and disease. PMID:26185746
Screening of potential diagnostic markers and therapeutic targets against colorectal cancer. PMID:26185457
ZNF555 protein binds to transcriptional activator site of 4qA allele and ANT1: potential implication in Facioscapulohumeral dystrophy. PMID:26184877
Research Resource: Androgen Receptor Activity Is Regulated Through the Mobilization of Cell Surface Receptor Networks. PMID:26181434
Interaction networks for identifying coupled molecular processes in microbial communities. PMID:26180552
Nonrandom Distribution of miRNAs Genes and Single Nucleotide Variants in Keratoconus Loci. PMID:26176855
Meta-Analysis of Placental Transcriptome Data Identifies a Novel Molecular Pathway Related to Preeclampsia. PMID:26171964
Transcriptomes analysis of Aeromonas molluscorum Av27 cells exposed to tributyltin (TBT): Unravelling the effects from the molecular level to the organism. PMID:26171931
Integrative proteomics to understand the transmission mechanism of Barley yellow dwarf virus-GPV by its insect vector Rhopalosiphum padi. PMID:26161807
Metagenomic insights into strategies of aerobic and anaerobic carbon and nitrogen transformation in boreal lakes. PMID:26159227
A reproducible approach to high-throughput biological data acquisition and integration. PMID:26157642
Comprehensive comparison of large-scale tissue expression datasets. PMID:26157623
Restoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degeneration. PMID:26150894
Proteome profiling of heat, oxidative, and salt stress responses in Thermococcus kodakarensis KOD1. PMID:26150806
Lung Transcriptomics during Protective Ventilatory Support in Sepsis-Induced Acute Lung Injury. PMID:26147972
iCOSSY: An Online Tool for Context-Specific Subnetwork Discovery from Gene Expression Data. PMID:26147457
Time-course gene profiling and networks in demethylated retinoblastoma cell line. PMID:26143641
Phosphorylation of ubiquitin at Ser65 affects its polymerization, targets, and proteome-wide turnover. PMID:26142280
Using prior knowledge from cellular pathways and molecular networks for diagnostic specimen classification. PMID:26141830
Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation. PMID:26140597
Possible functional links among brain- and skull-related genes selected in modern humans. PMID:26136701
Pathway and network analysis of cancer genomes. PMID:26125594
Functional fingerprinting of human mesenchymal stem cells using high-throughput RNAi screening. PMID:26120366
Functional conservation of an ancestral Pellino protein in helminth species. PMID:26120048
Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection. PMID:26118995
Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease. PMID:26113417
iTRAQ-based quantitative proteomics analysis of rice leaves infected by Rice stripe virus reveals several proteins involved in symptom formation. PMID:26113023
Surfing the Protein-Protein Interaction Surface Using Docking Methods: Application to the Design of PPI Inhibitors. PMID:26111183
NET-GE: a novel NETwork-based Gene Enrichment for detecting biological processes associated to Mendelian diseases. PMID:26110971
Opposite Expression of SPARC between the Liver and Pancreas in Streptozotocin-Induced Diabetic Rats. PMID:26110898
A New Combinatorial Optimization Approach for Integrated Feature Selection Using Different Datasets: A Prostate Cancer Transcriptomic Study. PMID:26106884
Identifying Highly Penetrant Disease Causal Mutations Using Next Generation Sequencing: Guide to Whole Process. PMID:26106619
Publisher’s Note:Abstraction for data integration:Fusing mammalian molecular, cellular and phenotype big datasets for better knowledge extraction. PMID:26101093
A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat. PMID:26100814
Predicting and exploring network components involved in pathogenesis in the malaria parasite via novel subnetwork alignments. PMID:26100579
Network-based gene prediction for Plasmodium falciparum malaria towards genetics-based drug discovery. PMID:26099491
Network-based survival-associated module biomarker and its crosstalk with cell death genes in ovarian cancer. PMID:26099452
A meta-analysis to evaluate the cellular processes regulated by the interactome of endogenous and over-expressed estrogen receptor alpha. PMID:26097882
Gene expression profiling analysis of osteosarcoma cell lines. PMID:26096802
Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway. PMID:26092128
Quantitative Circadian Phosphoproteomic Analysis of Arabidopsis Reveals Extensive Clock Control of Key Components in Physiological, Metabolic, and Signaling Pathways. PMID:26091701
Proteomic Analysis of Interaction between a Plant Virus and Its Vector Insect Reveals New Functions of Hemipteran Cuticular Protein. PMID:26091699
Pathway-Dependent Effectiveness of Network Algorithms for Gene Prioritization. PMID:26091506
Molecular-docking study of malaria drug target enzyme transketolase in Plasmodium falciparum 3D7 portends the novel approach to its treatment. PMID:26089981
Comprehensive analysis of gene-expression profile in chronic obstructive pulmonary disease. PMID:26089660
By the company they keep: interaction networks define the binding ability of transcription factors. PMID:26089389
Characterization of the Tyrosine Kinase-Regulated Proteome in Breast Cancer by Combined use of RNA interference (RNAi) and Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC) Quantitative Proteomics. PMID:26089344
Pareto Optimization Identifies Diverse Set of Phosphorylation Signatures Predicting Response to Treatment with Dasatinib. PMID:26083411
Integrated web visualizations for protein-protein interaction databases. PMID:26077899
Multiblock discriminant analysis for integrative genomic study. PMID:26075260
System-wide identification of wild-type SUMO-2 conjugation sites. PMID:26073453
Exploiting ontology graph for predicting sparsely annotated gene function. PMID:26072504
Improving compound-protein interaction prediction by building up highly credible negative samples. PMID:26072486
Simultaneous Pathoproteomic Evaluation of the Dystrophin-Glycoprotein Complex and Secondary Changes in the mdx-4cv Mouse Model of Duchenne Muscular Dystrophy. PMID:26067837
Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds. PMID:26064904
Identifying diabetes-related important protein targets with few interacting partners with the PageRank algorithm. PMID:26064627
Systems-level quantification of division timing reveals a common genetic architecture controlling asynchrony and fate asymmetry. PMID:26063786
Novel Serum Biomarkers to Differentiate Cholangiocarcinoma from Benign Biliary Tract Diseases Using a Proteomic Approach. PMID:26060332
Gene set analysis: A step-by-step guide. PMID:26059482
Network-Based Analysis on Orthogonal Separation of Human Plasma Uncovers Distinct High Density Lipoprotein Complexes. PMID:26057100
Study of phosphorylation events for cancer diagnoses and treatment. PMID:26055493
Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs. PMID:26055452
Differential Expression Profile of Chicken Embryo Fibroblast DF-1 Cells Infected with Cell-Adapted Infectious Bursal Disease Virus. PMID:26053856
Functional Identification of Target by Expression Proteomics (FITExP) reveals protein targets and highlights mechanisms of action of small molecule drugs. PMID:26052917
ComiRNet: a web-based system for the analysis of miRNA-gene regulatory networks. PMID:26051695
A Network-Based Target Overlap Score for Characterizing Drug Combinations: High Correlation with Cancer Clinical Trial Results. PMID:26047322
Gene Expression Profiles of Chicken Embryo Fibroblasts in Response to Salmonella Enteritidis Infection. PMID:26046914
Analysis of the transcriptional regulation of cancer-related genes by aberrant DNA methylation of the cis-regulation sites in the promoter region during hepatocyte carcinogenesis caused by arsenic. PMID:26046465
Micro-RNAs Let7e and 126 in Plasma as Markers of Metabolic Dysfunction in 10 to 12 Years Old Children. PMID:26046362
Molecular mechanisms for alcoholic hepatitis based on analysis of gene expression profile. PMID:26045708
Genome-Wide Collation of the Plasmodium falciparum WDR Protein Superfamily Reveals Malarial Parasite-Specific Features. PMID:26043001
Inferring regulatory networks from experimental morphological phenotypes: a computational method reverse-engineers planarian regeneration. PMID:26042810
The Proteome of the Isolated Chlamydia trachomatis Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer Components. PMID:26042774
Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression. PMID:26040834
Phosphoproteome dynamics of Saccharomyces cerevisiae under heat shock and cold stress. PMID:26040289
Proteins Related to the Type I Secretion System Are Associated with Secondary SecA_DEAD Domain Proteins in Some Species of Planctomycetes, Verrucomicrobia, Proteobacteria, Nitrospirae and Chlorobi. PMID:26030905
A Dedicated Type II NADPH Dehydrogenase Performs the Penultimate Step in the Biosynthesis of Vitamin K1 in Synechocystis and Arabidopsis. PMID:26023160
Proteomic profile of KSR1-regulated signalling in response to genotoxic agents in breast cancer. PMID:26022350
Postnatal TLR2 activation impairs learning and memory in adulthood. PMID:26021559
The Hippo pathway promotes cell survival in response to chemical stress. PMID:26021298
Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci. PMID:26020271
INGA: protein function prediction combining interaction networks, domain assignments and sequence similarity. PMID:26019177
DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data. PMID:26013811
Databases for Microbiologists. PMID:26013493
The prognostic factors and multiple biomarkers in young patients with colorectal cancer. PMID:26013439
Systematic Genome-wide Screening and Prediction of microRNAs in EBOV During the 2014 Ebolavirus Outbreak. PMID:26011078
AMP-Activated Protein Kinase Regulates the Cell Surface Proteome and Integrin Membrane Traffic. PMID:26010094
SPECTRA: An Integrated Knowledge Base for Comparing Tissue and Tumor-Specific PPI Networks in Human. PMID:26005672
ProteINSIDE to Easily Investigate Proteomics Data from Ruminants: Application to Mine Proteome of Adipose and Muscle Tissues in Bovine Foetuses. PMID:26000831
Synergistic antifungal activity of berberine derivative B-7b and fluconazole. PMID:25992630
Carcinogenic Liver Fluke Secretes Extracellular Vesicles That Promote Cholangiocytes to Adopt a Tumorigenic Phenotype. PMID:25985904
Identification of Leaf Proteins Differentially Accumulated between Wheat Cultivars Distinct in Their Levels of Drought Tolerance. PMID:25984726
The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation. PMID:25981667
Identification of a 6-cytokine prognostic signature in patients with primary glioblastoma harboring M2 microglia/macrophage phenotype relevance. PMID:25978454
Dynamic network-based relevance score reveals essential proteins and functional modules in directed differentiation. PMID:25977693
Urothelial cancer gene regulatory networks inferred from large-scale RNAseq, Bead and Oligo gene expression data. PMID:25971253
IMP 2.0: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks. PMID:25969450
Screening of candidate genes in fibroblasts derived from patients with Dupuytren's contracture using bioinformatics analysis. PMID:25963801
MSCA: a spectral comparison algorithm between time series to identify protein-protein interactions. PMID:25963052
Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbations. PMID:25960144
ProtPhylo: identification of protein-phenotype and protein-protein functional associations via phylogenetic profiling. PMID:25956654
Zodiac: A Comprehensive Depiction of Genetic Interactions in Cancer by Integrating TCGA Data. PMID:25956356
Involvement of enhancer of zeste homolog 2 in cisplatin-resistance in ovarian cancer cells by interacting with several genes. PMID:25955318
The integral membrane protein ITM2A, a transcriptional target of PKA-CREB, regulates autophagic flux via interaction with the vacuolar ATPase. PMID:25951193
FlyNet: a versatile network prioritization server for the Drosophila community. PMID:25943544
FNTM: a server for predicting functional networks of tissues in mouse. PMID:25940632
Predicting peptide-mediated interactions on a genome-wide scale. PMID:25938916
Regulation of gene expression in rats with spinal cord injury based on microarray data. PMID:25936407
Organ-specific adaptive signaling pathway activation in metastatic breast cancer cells. PMID:25926557
Phosphoproteome Analysis Links Protein Phosphorylation to Cellular Remodeling and Metabolic Adaptation during Magnaporthe oryzae Appressorium Development. PMID:25926025
A Multivariate Computational Method to Analyze High-Content RNAi Screening Data. PMID:25918037
Protein expression profiles characterize distinct features of mouse cerebral cortices at different developmental stages. PMID:25915664
A review on computational systems biology of pathogen-host interactions. PMID:25914674
Gene expression of OCT4, SOX2, KLF4 and MYC (OSKM) induced pluripotent stem cells: identification for potential mechanisms. PMID:25907774
A Comprehensive Immunoreceptor Phosphotyrosine-based Signaling Network Revealed by Reciprocal Protein-Peptide Array Screening. PMID:25907764
Differential regulation of defense-related proteins in soybean during compatible and incompatible interactions between Phytophthora sojae and soybean by comparative proteomic analysis. PMID:25906415
Unveiling the Metabolic Pathways Associated with the Adaptive Reduction of Cell Size During Vibrio harveyi Persistence in Seawater Microcosms. PMID:25903990
Pathway reporter genes define molecular phenotypes of human cells. PMID:25903797
Targets of Wnt/ß-catenin transcription in penile carcinoma. PMID:25901368
Evolving transcriptomic fingerprint based on genome-wide data as prognostic tools in prostate cancer. PMID:25900404
HER2 and uPAR cooperativity contribute to metastatic phenotype of HER2-positive breast cancer. PMID:25897424
Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract. PMID:25896808
Association of brain immune genes with social behavior of inbred mouse strains. PMID:25895500
Identification of functional candidates amongst hypothetical proteins of Treponema pallidum ssp. pallidum. PMID:25894582
Plasmodium vivax inhibits erythroid cell growth through altered phosphorylation of the cytoskeletal protein ezrin. PMID:25889165
Prediction of host - pathogen protein interactions between Mycobacterium tuberculosis and Homo sapiens using sequence motifs. PMID:25887594
Test on existence of histology subtype-specific prognostic signatures among early stage lung adenocarcinoma and squamous cell carcinoma patients using a Cox-model based filter. PMID:25887039
Measuring semantic similarities by combining gene ontology annotations and gene co-function networks. PMID:25886899
Novel primary immunodeficiency candidate genes predicted by the human gene connectome. PMID:25883595
CellWhere: graphical display of interaction networks organized on subcellular localizations. PMID:25883154
ANDSystem: an Associative Network Discovery System for automated literature mining in the field of biology. PMID:25881313
REGULATOR: a database of metazoan transcription factors and maternal factors for developmental studies. PMID:25880930
Essentiality and centrality in protein interaction networks revisited. PMID:25880655
Molecular association of pathogenetic contributors to pre-eclampsia (pre-eclampsia associome). PMID:25879409
PheNetic: network-based interpretation of molecular profiling data. PMID:25878035
Mutation analysis in patients with total sperm immotility. PMID:25877373
Molecular mechanism of flocculation self-recognition in yeast and its role in mating and survival. PMID:25873380
Combining bevacizumab and chemoradiation in rectal cancer. Translational results of the AXEBeam trial. PMID:25867261
Prediction of cancer proteins by integrating protein interaction, domain frequency, and domain interaction data using machine learning algorithms. PMID:25866773
Heavy path mining of protein-protein associations in the malaria parasite. PMID:25861922
Identification of stage-specific biomarkers in lung adenocarcinoma based on RNA-seq data. PMID:25861020
An integrated network of microRNA and gene expression in ovarian cancer. PMID:25860109
Hippocampal transcriptome-guided genetic analysis of correlated episodic memory phenotypes in Alzheimer's disease. PMID:25859259
Multidimensional proteomics for cell biology. PMID:25857810
A temporal gate for viral enhancers to co-opt Toll-like-receptor transcriptional activation pathways upon acute infection. PMID:25856589
Integration of transcriptome and whole genomic resequencing data to identify key genes affecting swine fat deposition. PMID:25849573
A mutation in the NADH-dehydrogenase subunit 2 suppresses fibroblast aging. PMID:25839158
Islet adaptation to obesity and insulin resistance in WNIN/GR-Ob rats. PMID:25833252
An adenosine triphosphate-independent proteasome activator contributes to the virulence of Mycobacterium tuberculosis. PMID:25831519
The promise of multi-omics and clinical data integration to identify and target personalized healthcare approaches in autism spectrum disorders. PMID:25831060
Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. PMID:25829543
Impact of Leishmania infection on host macrophage nuclear physiology and nucleopore complex integrity. PMID:25826301
Single-Cell Based Quantitative Assay of Chromosome Transmission Fidelity. PMID:25823586
Transcriptomics of maternal and fetal membranes can discriminate between gestational-age matched preterm neonates with and without cognitive impairment diagnosed at 18-24 months. PMID:25822971
Novel Genes Affecting Blood Pressure Detected Via Gene-Based Association Analysis. PMID:25820152
Large-scale determination of absolute phosphorylation stoichiometries in human cells by motif-targeting quantitative proteomics. PMID:25814448
Label-free Quantitative Proteomics Reveals a Role for the Mycobacterium tuberculosis SecA2 Pathway in Exporting Solute Binding Proteins and Mce Transporters to the Cell Wall. PMID:25813378
Gene-based association analysis identified novel genes associated with bone mineral density. PMID:25811989
The effect of music performance on the transcriptome of professional musicians. PMID:25806429
Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. PMID:25790137
Deciphering deterioration mechanisms of complex diseases based on the construction of dynamic networks and systems analysis. PMID:25788156
Identification of B cells participated in the mechanism of postmenopausal women osteoporosis using microarray analysis. PMID:25785089
High throughput proteomic analysis and a comparative review identify the nuclear chaperone, Nucleophosmin among the common set of proteins modulated in Chikungunya virus infection. PMID:25782748
Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer's disease donor as a model for investigating AD-associated gene regulatory networks. PMID:25765079
Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells. PMID:25762744
Label-free profiling of white adipose tissue of rats exhibiting high or low levels of intrinsic exercise capacity. PMID:25758023
Quantitative proteome analysis of temporally resolved phagosomes following uptake via key phagocytic receptors. PMID:25755298
Spatial and temporal dynamics of the cardiac mitochondrial proteome. PMID:25752359
Pervasive variation of transcription factor orthologs contributes to regulatory network evolution. PMID:25748510
Annotated differentially expressed salivary proteins of susceptible and insecticide-resistant mosquitoes of Anopheles stephensi. PMID:25742511
Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. PMID:25737553
Computational modeling of drug response with applications to neuroscience. PMID:25733952
FR database 1.0: a resource focused on fruit development and ripening. PMID:25725058
Identification of crucial genes in intracranial aneurysm based on weighted gene coexpression network analysis. PMID:25721208
Physiological and proteomic analyses of leaves from the halophyte Tangut Nitraria reveals diverse response pathways critical for high salinity tolerance. PMID:25713577
Therapeutic opportunities within the DNA damage response. PMID:25709118
cisPath: an R/Bioconductor package for cloud users for visualization and management of functional protein interaction networks. PMID:25708840
Highlights from the Third International Society for Computational Biology (ISCB) European Student Council Symposium 2014. PMID:25708611
Molecular handoffs in nitrergic neurotransmission. PMID:25705621
Molecular Characterization of Legionellosis Drug Target Candidate Enzyme Phosphoglucosamine Mutase from Legionella pneumophila (strain Paris): An In Silico Approach. PMID:25705169
Oasis: online analysis of small RNA deep sequencing data. PMID:25701573
The roles of post-translational modifications in the context of protein interaction networks. PMID:25692714
Identification of mammalian proteins that collaborate with type III secretion system function: involvement of a chemokine receptor in supporting translocon activity. PMID:25691588
Genome-wide identification, classification and functional analyses of the bHLH transcription factor family in the pig, Sus scrofa. PMID:25687626
The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network. PMID:25687571
Arginine-rhamnosylation as new strategy to activate translation elongation factor P. PMID:25686373
Eukaryotic LYR Proteins Interact with Mitochondrial Protein Complexes. PMID:25686363
High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice. PMID:25685688
Systematic Discovery of Human Gene Function and Principles of Modular Organization through Phylogenetic Profiling. PMID:25683721
Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator. PMID:25680957
Crucial microRNAs and genes of human primary breast cancer explored by microRNA-mRNA integrated analysis. PMID:25680412
Evolutionary signatures amongst disease genes permit novel methods for gene prioritization and construction of informative gene-based networks. PMID:25679399
Rare variants at 16p11.2 are associated with common variable immunodeficiency. PMID:25678086
Systems pharmacology augments drug safety surveillance. PMID:25670520
In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma. PMID:25669970
Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. PMID:25669599
Developing a molecular roadmap of drug-food interactions. PMID:25668218
Mapping native disulfide bonds at a proteome scale. PMID:25664544
A neurogenetics approach to defining differential susceptibility to institutional care. PMID:25663728
Dsp rul: a spontaneous mouse mutation in desmoplakin as a model of Carvajal-Huerta syndrome. PMID:25659760
Identification of circulating biomarkers in sera of Plasmodium knowlesi-infected malaria patients--comparison against Plasmodium vivax infection. PMID:25656928
Examination of the Staphylococcus aureus nitric oxide reductase (saNOR) reveals its contribution to modulating intracellular NO levels and cellular respiration. PMID:25651868
miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy. PMID:25650662
EcoliNet: a database of cofunctional gene network for Escherichia coli. PMID:25650278
Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways. PMID:25650115
Whole genome sequencing reveals a de novo SHANK3 mutation in familial autism spectrum disorder. PMID:25646853
Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans. PMID:25646306
Quantitative and logic modelling of molecular and gene networks. PMID:25645874
Molecular insights into the binding of coenzyme F420 to the conserved protein Rv1155 from Mycobacterium tuberculosis. PMID:25644473
ID helix-loop-helix proteins as determinants of cell survival in B-cell chronic lymphocytic leukemia cells in vitro. PMID:25644253
Comparative genomics reveals new candidate genes involved in selenium metabolism in prokaryotes. PMID:25638258
Dissecting the molecular properties of prokaryotic flotillins. PMID:25635948
Assessment of the olfactory function in Italian patients with type 3 von Willebrand disease caused by a homozygous 253 Kb deletion involving VWF and TMEM16B/ANO2. PMID:25635880
A global microRNA screen identifies regulators of the ErbB receptor signaling network. PMID:25630670
Re-annotation of the sequence > annotation: opportunities for the functional microbiologist. PMID:25627838
Candidate prioritization for low-abundant differentially expressed proteins in 2D-DIGE datasets. PMID:25627479
Network representations of immune system complexity. PMID:25625853
Using comparative genomics to drive new discoveries in microbiology. PMID:25617609
Complete Genome Sequence of Bacillus pumilus Strain WP8, an Efficient Plant Growth-Promoting Rhizobacterium. PMID:25614565
Emergence of differentially regulated pathways associated with the development of regional specificity in chicken skin. PMID:25612663
BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1. PMID:25609615
Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation. PMID:25609184
atBRX1-1 and atBRX1-2 are involved in an alternative rRNA processing pathway in Arabidopsis thaliana. PMID:25605960
Histology-directed and imaging mass spectrometry: An emerging technology in ectopic calcification. PMID:25595835
Bisphenol A alters autonomic tone and extracellular matrix structure and induces sex-specific effects on cardiovascular function in male and female CD-1 mice. PMID:25594700
Identifying mutation specific cancer pathways using a structurally resolved protein interaction network. PMID:25592571
New mass-spectrometry-compatible degradable surfactant for tissue proteomics. PMID:25589168
Identification of molecular signature of head and neck cancer stem-like cells. PMID:25588898
Comparative genomic analysis of evolutionarily conserved but functionally uncharacterized membrane proteins in archaea: Prediction of novel components of secretion, membrane remodeling and glycosylation systems. PMID:25583072
Global transcriptional disturbances underlie Cornelia de Lange syndrome and related phenotypes. PMID:25574841
Genome-wide Analysis of Mycoplasma hominis for the Identification of Putative Therapeutic Targets. PMID:25574133
Discovery of small protein complexes from PPI networks with size-specific supervised weighting. PMID:25559663
Pathway and network approaches for identification of cancer signature markers from omics data. PMID:25553089
Identifying glioblastoma gene networks based on hypergeometric test analysis. PMID:25551752
EvoTol: a protein-sequence based evolutionary intolerance framework for disease-gene prioritization. PMID:25550428
Identification of protein network alterations upon retinal ischemia-reperfusion injury by quantitative proteomics using a Rattus norvegicus model. PMID:25549249
Exploring systems affected by the heat shock response in Plasmodium falciparum via protein association networks. PMID:25539848
Reproducibility enhancement and differential expression of non predefined functional gene sets in human genome. PMID:25539829
Comparative metagenomic and metatranscriptomic analyses of microbial communities in acid mine drainage. PMID:25535937
SILAC-iPAC: a quantitative method for distinguishing genuine from non-specific components of protein complexes by parallel affinity capture. PMID:25534881
Selecting causal genes from genome-wide association studies via functionally coherent subnetworks. PMID:25532137
Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson's disease. PMID:25528190
The acetate switch of an intestinal pathogen disrupts host insulin signaling and lipid metabolism. PMID:25525791
Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach. PMID:25525446
Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas. PMID:25521819
19q13.11 microdeletion concomitant with ins(2;19)(p25.3;q13.1q13.4)dn in a boy: potential role of UBA2 in the associated phenotype. PMID:25516771
An integrative computational approach for prioritization of genomic variants. PMID:25506935
High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow derived macrophages. PMID:25504905
Microarray analysis for differentially expressed genes of patients undergoing total knee arthroplasty with ischemia preconditioning. PMID:25496472
Feedforward regulation of mRNA stability by prolonged extracellular signal-regulated kinase activity. PMID:25491268
Identification of the interactors of human nibrin (NBN) and of its 26 kDa and 70 kDa fragments arising from the NBN 657del5 founder mutation. PMID:25485873
Graphical algorithm for integration of genetic and biological data: proof of principle using psoriasis as a model. PMID:25480373
LuxR solos in Photorhabdus species. PMID:25478328
The predicted ABC transporter AbcEDCBA is required for type IV secretion system expression and lysosomal evasion by Brucella ovis. PMID:25474545
Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex. PMID:25473596
Identification and analysis of potential targets in Streptococcus sanguinis using computer aided protein data analysis. PMID:25473301
Synergy-COPD: a systems approach for understanding and managing chronic diseases. PMID:25472826
Systems Medicine: from molecular features and models to the clinic in COPD. PMID:25471042
Diffusion of information throughout the host interactome reveals gene expression variations in network proximity to target proteins of hepatitis C virus. PMID:25461596
Profilin-1 overexpression in MDA-MB-231 breast cancer cells is associated with alterations in proteomics biomarkers of cell proliferation, survival, and motility as revealed by global proteomics analyses. PMID:25454514
Network analyses of sperm-egg recognition and binding: ready to rethink fertility mechanisms? PMID:25454512
Evaluative profiling of arsenic sensing and regulatory systems in the human microbiome project genomes. PMID:25452698
Gene expression microarray analysis of the sciatic nerve of mice with diabetic neuropathy. PMID:25435094
Analysis of the protein-protein interaction networks of differentially expressed genes in pulmonary embolism. PMID:25434468
A directed-overflow and damage-control N-glycosidase in riboflavin biosynthesis. PMID:25431972
Protein-protein Interaction Networks of E. coli and S. cerevisiae are similar. PMID:25431098
Host genetics of Epstein-Barr virus infection, latency and disease. PMID:25430668
The BioGRID interaction database: 2015 update. PMID:25428363
Conserved abundance and topological features in chromatin-remodeling protein interaction networks. PMID:25427557
Genome wide in silico analysis of Plasmodium falciparum phosphatome. PMID:25425018
Lysine malonylation is elevated in type 2 diabetic mouse models and enriched in metabolic associated proteins. PMID:25418362
A comprehensive analysis of candidate genes and pathways in pancreatic cancer. PMID:25409614
Anatomo-proteomic characterization of human basal ganglia: focus on striatum and globus pallidus. PMID:25406675
Computational surprisal analysis speeds-up genomic characterization of cancer processes. PMID:25405334
Text mining in cancer gene and pathway prioritization. PMID:25392685
COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems. PMID:25392420
PubAngioGen: a database and knowledge for angiogenesis and related diseases. PMID:25392416
Identification of genes associated with the differentiation potential of adipose-derived stem cells to osteocytes or myocytes. PMID:25385480
A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools. PMID:25380778
Proteomics for systems toxicology. PMID:25379146
A derived network-based interferon-related signature of human macrophages responding to Mycobacterium tuberculosis. PMID:25371902
Quantitative proteomics of delirium cerebrospinal fluid. PMID:25369144
Sustained mitogen-activated protein kinase activation reprograms defense metabolism and phosphoprotein profile in Arabidopsis thaliana. PMID:25368622
Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes. PMID:25367092
A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks. PMID:25362484
MobiDB 2.0: an improved database of intrinsically disordered and mobile proteins. PMID:25361972
GeneFriends: a human RNA-seq-based gene and transcript co-expression database. PMID:25361971
PTMcode v2: a resource for functional associations of post-translational modifications within and between proteins. PMID:25361965
A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis. PMID:25361581
STRING v10: protein-protein interaction networks, integrated over the tree of life. PMID:25352553
Effects of changes in food supply at the time of sex differentiation on the gonadal transcriptome of juvenile fish. Implications for natural and farmed populations. PMID:25340342
Protein profiles reveal diverse responsive signaling pathways in kernels of two maize inbred lines with contrasting drought sensitivity. PMID:25334062
Expression profiling of mitochondrial voltage-dependent anion channel-1 associated genes predicts recurrence-free survival in human carcinomas. PMID:25333947
The human DEPhOsphorylation database DEPOD: a 2015 update. PMID:25332398
Profound impact of Hfq on nutrient acquisition, metabolism and motility in the plant pathogen Agrobacterium tumefaciens. PMID:25330313
Exploiting holistic approaches to model specificity in protein phosphorylation. PMID:25324856
P2CS: updates of the prokaryotic two-component systems database. PMID:25324303
Novel function discovery with GeneMANIA: a new integrated resource for gene function prediction in Escherichia coli. PMID:25316676
A curated C. difficile strain 630 metabolic network: prediction of essential targets and inhibitors. PMID:25315994
Inferring protein modulation from gene expression data using conditional mutual information. PMID:25314274
Copy number loss of the interferon gene cluster in melanomas is linked to reduced T cell infiltrate and poor patient prognosis. PMID:25314013
SMART: recent updates, new developments and status in 2015. PMID:25300481
Messenger RNA degradation in bacterial cells. PMID:25292357
Molecular mechanism underlying the impact of vitamin D on disease activity of MS. PMID:25285313
Effect of light on global gene expression in the neuroglobin-deficient mouse retina. PMID:25279145
Computational biophysical, biochemical, and evolutionary signature of human R-spondin family proteins, the member of canonical Wnt/β-catenin signaling pathway. PMID:25276837
Systematic expression profiling analysis identifies specific microRNA-gene interactions that may differentiate between active and latent tuberculosis infection. PMID:25276827
Comparative proteomics and glycoproteomics of plasma proteins in Indian visceral leishmaniasis. PMID:25276097
Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions. PMID:25275790
Identification of host-immune response protein candidates in the sera of human oral squamous cell carcinoma patients. PMID:25272005
CisMiner: genome-wide in-silico cis-regulatory module prediction by fuzzy itemset mining. PMID:25268582
Widespread signals of convergent adaptation to high altitude in Asia and america. PMID:25262650
High dose ionizing radiation regulates micro RNA and gene expression changes in human peripheral blood mononuclear cells. PMID:25257395
Gene expression variability as a unifying element of the pluripotency network. PMID:25254348
Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology. PMID:25254076
Structure-based inhibition of protein-protein interactions. PMID:25253637
A random set scoring model for prioritization of disease candidate genes using protein complexes and data-mining of GeneRIF, OMIM and PubMed records. PMID:25253562
The 'dnet' approach promotes emerging research on cancer patient survival. PMID:25246945
Transcriptomic response of Enterococcus faecalis V583 to low hydrogen peroxide levels. PMID:25245959
Alterations in the nuclear proteome of HIV-1 infected T-cells. PMID:25240327
Differential proteomic profiling unveils new molecular mechanisms associated with mitochondrial complex III deficiency. PMID:25239759
Proteome analysis of human sebaceous follicle infundibula extracted from healthy and acne-affected skin. PMID:25238151
Single nucleotide variations: biological impact and theoretical interpretation. PMID:25234433
A high-resolution network model for global gene regulation in Mycobacterium tuberculosis. PMID:25232098
BRAF activates and physically interacts with PAK to regulate cell motility. PMID:25228413
Protein deep sequencing applied to biobank samples from patients with pancreatic cancer. PMID:25216700
GSAASeqSP: a toolset for gene set association analysis of RNA-Seq data. PMID:25213199
Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast. PMID:25208583
Insilico analysis of hypothetical proteins unveils putative metabolic pathways and essential genes in Leishmania donovani. PMID:25206363
Gene expression profiles on predicting protein interaction network and exploring of new treatments for lung cancer. PMID:25205123
Biological network exploration with Cytoscape 3. PMID:25199793
A proteomics analysis to evaluate cytotoxicity in NRK-52E cells caused by unmodified Nano-Fe₃O₄. PMID:25197711
A sentinel protein assay for simultaneously quantifying cellular processes. PMID:25194849
The DNA methylation-regulated miR-193a-3p dictates the multi-chemoresistance of bladder cancer via repression of SRSF2/PLAU/HIC2 expression. PMID:25188512
Revealing molecular mechanisms by integrating high-dimensional functional screens with protein interaction data. PMID:25188415
Analysis of gene expression profiles of soft tissue sarcoma using a combination of knowledge-based filtering with integration of multiple statistics. PMID:25188299
An siRNA screen of membrane trafficking genes highlights pathways common to HIV-1 and M-PMV virus assembly and release. PMID:25187981
Identification of glutamate ABC-Transporter component in Clostridium perfringens as a putative drug target. PMID:25187678
An overview of the neurobiology of suicidal behaviors as one meta-system. PMID:25178164
Centriolar satellites: key mediators of centrosome functions. PMID:25173771
Pharmacogenetic effects of 'candidate gene complexes' on stroke in the GenHAT study. PMID:25171760
Network-based analysis reveals distinct association patterns in a semantic MEDLINE-based drug-disease-gene network. PMID:25170419
A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. PMID:25170077
Functional and genomic context in pathway analysis of GWAS data. PMID:25154796
A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice. PMID:25151659
Computational identification of surrogate genes for prostate cancer phases using machine learning and molecular network analysis. PMID:25151146
Asymmetric mRNA localization contributes to fidelity and sensitivity of spatially localized systems. PMID:25150862
Microarray analysis of the transcriptional responses of Porphyromonas gingivalis to polyphosphate. PMID:25148905
Human factors and pathways essential for mediating epigenetic gene silencing. PMID:25147916
Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma. PMID:25147914
MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib. PMID:25147211
Mouse IDGenes: a reference database for genetic interactions in the developing mouse brain. PMID:25145340
Network biology in medicine and beyond. PMID:25140061
From pathways to networks: connecting dots by establishing protein-protein interaction networks in signaling pathways using affinity purification and mass spectrometry. PMID:25137225
Nuclear cytoplasmic trafficking of proteins is a major response of human fibroblasts to oxidative stress. PMID:25133973
PPI network analysis of mRNA expression profile of ezrin knockdown in esophageal squamous cell carcinoma. PMID:25126570
Gene expression profiling analysis of locus coeruleus in idiopathic Parkinson's disease by bioinformatics. PMID:25116258
Lean Big Data integration in systems biology and systems pharmacology. PMID:25109570
Bioinformatic approaches to augment study of epithelial-to-mesenchymal transition in lung cancer. PMID:25096367
Phen-Gen: combining phenotype and genotype to analyze rare disorders. PMID:25086502
Walking the interactome for candidate prioritization in exome sequencing studies of Mendelian diseases. PMID:25078397
Proteomic analysis reveals age-related changes in tendon matrix composition, with age- and injury-specific matrix fragmentation. PMID:25077967
PPI layouts: BioJS components for the display of Protein-Protein Interactions. PMID:25075288
Toward a systems-level understanding of gene regulatory, protein interaction, and metabolic networks in cyanobacteria. PMID:25071821
Arabidopsis and maize RidA proteins preempt reactive enamine/imine damage to branched-chain amino acid biosynthesis in plastids. PMID:25070638
Phylobiochemical characterization of class-Ib aspartate/prephenate aminotransferases reveals evolution of the plant arogenate phenylalanine pathway. PMID:25070637
The PSI family of nuclear proteins is required for growth in arabidopsis. PMID:25062973
iRegulon: from a gene list to a gene regulatory network using large motif and track collections. PMID:25058159
The landscape of protein biomarkers proposed for periodontal disease: markers with functional meaning. PMID:25057495
Genome-wide prediction of cancer driver genes based on SNP and cancer SNV data. PMID:25057442
The structural network of Interleukin-10 and its implications in inflammation and cancer. PMID:25056661
The liver transcriptome of two full-sibling Songliao black pigs with extreme differences in backfat thickness. PMID:25053997
Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake. PMID:25044324
Bioinformatic analysis of proteomics data. PMID:25033288
KIFCI, a novel putative prognostic biomarker for ovarian adenocarcinomas: delineating protein interaction networks and signaling circuitries. PMID:25028599
Identification and consequences of miRNA-target interactions--beyond repression of gene expression. PMID:25022902
Investigating co-evolution of functionally associated phosphosites in human. PMID:25005854
Radiosensitization of human leukemic HL-60 cells by ATR kinase inhibitor (VE-821): phosphoproteomic analysis. PMID:25003641
An integrative analysis of meningioma tumors reveals the determinant genes and pathways of malignant transformation. PMID:25003081
Expanding the computational toolbox for mining cancer genomes. PMID:25001846
Leveraging structure for enzyme function prediction: methods, opportunities, and challenges. PMID:24998033
Coherent somatic mutation in autoimmune disease. PMID:24988487
Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks. PMID:24980702
Integrated high-throughput analysis identifies Sp1 as a crucial determinant of p53-mediated apoptosis. PMID:24971482
Novel insights into the regulatory architecture of CD4+ T cells in rheumatoid arthritis. PMID:24959711
Bioinformatics analyses combined microarray identify the deregulated microRNAs in oral cancer. PMID:24959249
Insights into pathophysiology of dystropy through the analysis of gene networks: an example of bronchial asthma and tuberculosis. PMID:24954693
The emerging era of genomic data integration for analyzing splice isoform function. PMID:24951248
Lynx web services for annotations and systems analysis of multi-gene disorders. PMID:24948611
The chromatin regulator DMAP1 modulates activity of the nuclear factor B (NF-B) transcription factor Relish in the Drosophila innate immune response. PMID:24947515
Identification of a duplication within the GDF9 gene and novel candidate genes for primary ovarian insufficiency (POI) by a customized high-resolution array comparative genomic hybridization platform. PMID:24939957
New directions for diffusion-based network prediction of protein function: incorporating pathways with confidence. PMID:24931987
Conserved evolutionary units in the heme-copper oxidase superfamily revealed by novel homologous protein families. PMID:24931479
Stoichiometry of site-specific lysine acetylation in an entire proteome. PMID:24917678
Extracellular matrix and cytochrome P450 gene expression can distinguish steatohepatitis from steatosis in mice. PMID:24913135
Pathway and network analysis in proteomics. PMID:24911777
Plant, animal, and fungal micronutrient queuosine is salvaged by members of the DUF2419 protein family. PMID:24911101
Identification of potential therapeutic targets in a model of neuropathic pain. PMID:24904634
Network Assessor: an automated method for quantitative assessment of a network's potential for gene function prediction. PMID:24904632
Carnitine/acylcarnitine translocase and carnitine palmitoyltransferase 2 form a complex in the inner mitochondrial membrane. PMID:24898781
Selenoprotein S is involved in maintenance and transport of multiprotein complexes. PMID:24897171
Structural bioinformatics of the interactome. PMID:24895853
Protein-protein interactions and genetic diseases: The interactome. PMID:24892209
Differential proteomic analysis of the pancreas of diabetic db/db mice reveals the proteins involved in the development of complications of diabetes mellitus. PMID:24886809
Exploring mechanisms of diet-colon cancer associations through candidate molecular interaction networks. PMID:24886433
Large-scale phosphoproteome analysis in seedling leaves of Brachypodium distachyon L. PMID:24885693
Investigating perturbed pathway modules from gene expression data via structural equation models. PMID:24885496
A web-based protein interaction network visualizer. PMID:24885165
Biophysical constraints on the evolution of tissue structure and function. PMID:24882821
Prediction and redesign of protein-protein interactions. PMID:24878423
NetworkAnalyst--integrative approaches for protein-protein interaction network analysis and visual exploration. PMID:24861621
EvoCor: a platform for predicting functionally related genes using phylogenetic and expression profiles. PMID:24848012
Think globally and solve locally: secondary memory-based network learning for automated multi-species function prediction. PMID:24843788
Shotgun proteomics: identification of unique protein profiles of apoptotic bodies from biliary epithelial cells. PMID:24841946
Application of fluorescence two-dimensional difference in-gel electrophoresis as a proteomic biomarker discovery tool in muscular dystrophy research. PMID:24833232
Unveiling novel interactions of histone chaperone Asf1 linked to TREX-2 factors Sus1 and Thp1. PMID:24824343
Integrated analysis of gene network in childhood leukemia from microarray and pathway databases. PMID:24822192
Genome scale modeling in systems biology: algorithms and resources. PMID:24822031
Host responses to the pathogen Mycobacterium avium subsp. paratuberculosis and beneficial microbes exhibit host sex specificity. PMID:24814797
Identification of 2R-ohnologue gene families displaying the same mutation-load skew in multiple cancers. PMID:24806839
Transcriptional atlas of cardiogenesis maps congenital heart disease interactome. PMID:24803680
RAID: a comprehensive resource for human RNA-associated (RNA-RNA/RNA-protein) interaction. PMID:24803509
Modeling genome-wide dynamic regulatory network in mouse lungs with influenza infection using high-dimensional ordinary differential equations. PMID:24802016
Platelet-derived growth factor receptor beta: a novel urinary biomarker for recurrence of non-muscle-invasive bladder cancer. PMID:24801713
microRNA-148a dysregulation discriminates poor prognosis of hepatocellular carcinoma in association with USP4 overexpression. PMID:24798342
Identification of small ubiquitin-like modifier substrates with diverse functions using the Xenopus egg extract system. PMID:24797264
Fifteen years SIB Swiss Institute of Bioinformatics: life science databases, tools and support. PMID:24792157
Proteomic profiling of the dystrophin-deficient mdx phenocopy of dystrophinopathy-associated cardiomyopathy. PMID:24772416
N-cadherin/catenin complex as a master regulator of intercalated disc function. PMID:24766605
The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex. PMID:24748658
A three step network based approach (TSNBA) to finding disease molecular signature and key regulators: a case study of IL-1 and TNF-alpha stimulated inflammation. PMID:24747419
Ferritin heavy chain in triple negative breast cancer: a favorable prognostic marker that relates to a cluster of differentiation 8 positive (CD8+) effector T-cell response. PMID:24742827
Proteomics, metabolomics, and protein interactomics in the characterization of the molecular features of major depressive disorder. PMID:24733971
Modulation of the chromatin phosphoproteome by the Haspin protein kinase. PMID:24732914
Systematic variation in the pattern of gene paralog retention between the teleost superorders Ostariophysi and Acanthopterygii. PMID:24732281
Uncovering the pathogenesis and identifying novel targets of pancreatic cancer using bioinformatics approach. PMID:24728565
What's that gene (or protein)? Online resources for exploring functions of genes, transcripts, and proteins. PMID:24723265
Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. PMID:24721909
Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. PMID:24719451
Progress and challenges in the computational prediction of gene function using networks: 2012-2013 update. PMID:24715959
Comprehensive genotyping and clinical characterisation reveal 27 novel NKX2-1 mutations and expand the phenotypic spectrum. PMID:24714694
DoReMi: context-based prioritization of linear motif matches. PMID:24711967
Identifying biological pathways that underlie primordial short stature using network analysis. PMID:24711643
Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia. PMID:24704148
Emerging genetic basis of osteochondritis dissecans. PMID:24698039
HGCS: an online tool for prioritizing disease-causing gene variants by biological distance. PMID:24694260
NatalieQ: a web server for protein-protein interaction network querying. PMID:24690407
Deciphering intrafamilial phenotypic variability by exome sequencing in a Bardet-Biedl family. PMID:24689075
Biblio-MetReS for user-friendly mining of genes and biological processes in scientific documents. PMID:24688854
An In Silico Approach for Characterization of an Aminoglycoside Antibiotic-Resistant Methyltransferase Protein from Pyrococcus furiosus (DSM 3638). PMID:24683305
High-throughput quantitative proteomic analysis of dengue virus type 2 infected A549 cells. PMID:24671231
GeneSense: a new approach for human gene annotation integrated with protein-protein interaction networks. PMID:24667292
Identification of a novel nutrient-sensing histidine kinase/response regulator network in Escherichia coli. PMID:24659770
Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry. PMID:24625528
Variants of CEP68 gene are associated with acute urticaria/angioedema induced by multiple non-steroidal anti-inflammatory drugs. PMID:24618698
Identification and biosynthesis of a novel xanthomonadin-dialkylresorcinol-hybrid from Azoarcus sp. BH72. PMID:24618669
COMPARTMENTS: unification and visualization of protein subcellular localization evidence. PMID:24573882
Quantitative proteomics by SWATH-MS reveals altered expression of nucleic acid binding and regulatory proteins in HIV-1-infected macrophages. PMID:24564501
New insights into the evolution and structure of Colletotrichum plant-like subtilisins (CPLSs). PMID:24563701
Prediction of CTL epitope, in silico modeling and functional analysis of cytolethal distending toxin (CDT) protein of Campylobacter jejuni. PMID:24552167
Late multiple organ surge in interferon-regulated target genes characterizes staphylococcal enterotoxin B lethality. PMID:24551153
Proteomics of a fuzzy organelle: interphase chromatin. PMID:24534090
Cd²⁺-induced alteration of the global proteome of human skin fibroblast cells. PMID:24527689
In Silico Molecular Characterization of Cysteine Protease YopT from Yersinia pestis by Homology Modeling and Binding Site Identification. PMID:24526834
Importance of collection in gene set enrichment analysis of drug response in cancer cell lines. PMID:24522610
Functional analysis of a subtilisin-like serine protease gene from biocontrol fungus Trichoderma harzianum. PMID:24500477
Computational investigation of pkcβ inhibitors for the treatment of diabetic retinopathy. PMID:24497733
Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices. PMID:24489787
Cleavage of E-cadherin and β-catenin by calpain affects Wnt signaling and spheroid formation in suspension cultures of human pluripotent stem cells. PMID:24482122
Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine. PMID:24479672
Proteomic profile of Cryptococcus neoformans biofilm reveals changes in metabolic processes. PMID:24467693
Initiation of the flexirubin biosynthesis in Chitinophaga pinensis. PMID:24467333
Review of biological network data and its applications. PMID:24465231
A widespread bacteriophage abortive infection system functions through a Type IV toxin-antitoxin mechanism. PMID:24465005
The evolution of lncRNA repertoires and expression patterns in tetrapods. PMID:24463510
A two-stage association study suggests BRAP as a susceptibility gene for schizophrenia. PMID:24454952
In-silico analysis and expression profiling implicate diverse role of EPSPS family genes in regulating developmental and metabolic processes. PMID:24450620
Determinants of expression variability. PMID:24435799
Identification of low-molecular-weight compounds inhibiting growth of corynebacteria: potential lead compounds for antibiotics. PMID:24403054
TTSS2-deficient hha mutant of Salmonella Typhimurium exhibits significant systemic attenuation in immunocompromised hosts. PMID:24401482
Reconstruction and analysis of nutrient-induced phosphorylation networks in Arabidopsis thaliana. PMID:24400017
Automatic context-specific subnetwork discovery from large interaction networks. PMID:24392115
Transcriptomic changes induced by mycophenolic acid in gastric cancer cells. PMID:24349619
CyTargetLinker: a cytoscape app to integrate regulatory interactions in network analysis. PMID:24340000
Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis. PMID:24327959
Differentially expressed transcripts and dysregulated signaling pathways and networks in African American breast cancer. PMID:24324792
Mapping eQTLs in the Norfolk Island genetic isolate identifies candidate genes for CVD risk traits. PMID:24314549
Phylogeny, functional annotation, and protein interaction network analyses of the Xenopus tropicalis basic helix-loop-helix transcription factors. PMID:24312906
Functional categorization of transcriptome in the species Symphysodon aequifasciatus Pellegrin 1904 (Perciformes: Cichlidae) exposed to benzo[a]pyrene and phenanthrene. PMID:24312524
STITCH 4: integration of protein-chemical interactions with user data. PMID:24293645
Network analysis of GWAS data. PMID:24287332
PortEco: a resource for exploring bacterial biology through high-throughput data and analysis tools. PMID:24285306
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. PMID:24284630
Protein-driven inference of miRNA-disease associations. PMID:24273243
Network portal: a database for storage, analysis and visualization of biological networks. PMID:24271392
CentrosomeDB: a new generation of the centrosomal proteins database for Human and Drosophila melanogaster. PMID:24270791
Lynx: a database and knowledge extraction engine for integrative medicine. PMID:24270788
Prioritizing genes responsible for host resistance to influenza using network approaches. PMID:24261899
Mycophenolic acid inhibits migration and invasion of gastric cancer cells via multiple molecular pathways. PMID:24260584
DNA hypermethylation and DNA hypomethylation is present at different loci in chronic kidney disease. PMID:24253112
A computational study identifies HIV progression-related genes using mRMR and shortest path tracing. PMID:24244287
Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity. PMID:24240700
Integrating protein-protein interaction networks with phenotypes reveals signs of interactions. PMID:24240319
Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines. PMID:24239728
Expression changes of ribosomal proteins in phosphate- and iron-deficient Arabidopsis roots predict stress-specific alterations in ribosome composition. PMID:24225185
Discover context-specific combinatorial transcription factor interactions by integrating diverse ChIP-Seq data sets. PMID:24217919
NPInter v2.0: an updated database of ncRNA interactions. PMID:24217916
UniHI 7: an enhanced database for retrieval and interactive analysis of human molecular interaction networks. PMID:24214987
Exploring extra-cellular proteins in methicillin susceptible and methicillin resistant Staphylococcus aureus by liquid chromatography-tandem mass spectrometry. PMID:24214678
CellFateScout - a bioinformatics tool for elucidating small molecule signaling pathways that drive cells in a specific direction. PMID:24206562
Measles contributes to rheumatoid arthritis: evidence from pathway and network analyses of genome-wide association studies. PMID:24204584
Transcription factors and genetic circuits orchestrating the complex, multilayered response of Clostridium acetobutylicum to butanol and butyrate stress. PMID:24196194
Status of large-scale analysis of post-translational modifications by mass spectrometry. PMID:24187339
FunCoup 3.0: database of genome-wide functional coupling networks. PMID:24185702
BloodChIP: a database of comparative genome-wide transcription factor binding profiles in human blood cells. PMID:24185696
A multifunctional protein EWS regulates the expression of Drosha and microRNAs. PMID:24185621
SIMAP--the database of all-against-all protein sequence similarities and annotations with new interfaces and increased coverage. PMID:24165881
A primer to frequent itemset mining for bioinformatics. PMID:24162173
On Crowd-verification of Biological Networks. PMID:24151423
Are graph databases ready for bioinformatics? PMID:24135261
Analytical tools and databases for metagenomics in the next-generation sequencing era. PMID:24124405
HTS-DB: an online resource to publish and query data from functional genomics high-throughput siRNA screening projects. PMID:24122843
Productivity and salinity structuring of the microplankton revealed by comparative freshwater metagenomics. PMID:24118837
Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes. PMID:24112857
Identifying reaction modules in metabolic pathways: bioinformatic deduction and experimental validation of a new putative route in purine catabolism. PMID:24093154
Porcine JAB1 significantly enhances apoptosis induced by staurosporine. PMID:24091666
CoCiter: an efficient tool to infer gene function by assessing the significance of literature co-citation. PMID:24086311
Drug discovery for autism spectrum disorder: challenges and opportunities. PMID:24080699
Deletion of lipoprotein PG0717 in Porphyromonas gingivalis W83 reduces gingipain activity and alters trafficking in and response by host cells. PMID:24069284
The coming of age of phosphoproteomics--from large data sets to inference of protein functions. PMID:24037665
Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila. PMID:24004689
Navigating traditional chinese medicine network pharmacology and computational tools. PMID:23983798
in silico analyses of metabolic pathway and protein interaction network for identification of next gen therapeutic targets in Chlamydophila pneumoniae. PMID:23904736
Green fluorescent protein expression triggers proteome changes in breast cancer cells. PMID:23899627
Maternal-fetal unit interactions and eutherian neocortical development and evolution. PMID:23882189
A graph kernel approach for alignment-free domain-peptide interaction prediction with an application to human SH3 domains. PMID:23813002
GeneMANIA prediction server 2013 update. PMID:23794635
Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: of gene prioritization and context dependence. PMID:23781200
Tumor necrosis factor receptor superfamily 10B (TNFRSF10B): an insight from structure modeling to virtual screening for designing drug against head and neck cancer. PMID:23724937
The cellular interactome of the coronavirus infectious bronchitis virus nucleocapsid protein and functional implications for virus biology. PMID:23637410
Computational solutions for omics data. PMID:23594911
Multi-parameter systematic strategies for predictive, preventive and personalised medicine in cancer. PMID:23339750 -
STRING 8--a global view on proteins and their functional interactions in 630 organisms
PubMed citations: 1166.
1166 articles citing: STRING 8--a global view on proteins and their functional interactions in 630 organisms
The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex. PMID:35918739
Metabolomics analysis of milk thistle lipids to identify drought-tolerant genes. PMID:35896570
Transcriptome Analysis Reveals Molecular Mechanisms under Salt Stress in Leaves of Foxtail Millet (Setaria italica L.). PMID:35890498
NSD1 Mutations in Sotos Syndrome Induce Differential Expression of Long Noncoding RNAs, miR646 and Genes Controlling the G2/M Checkpoint. PMID:35888078
Orphan GPR26 Counteracts Early Phases of Hyperglycemia-Mediated Monocyte Activation and Is Suppressed in Diabetic Patients. PMID:35885041
Analysis of the expression, function and signaling of glycogen phosphorylase isoforms in hepatocellular carcinoma. PMID:35761940
Salivary Proteomics Markers for Preclinical Sjögren's Syndrome: A Pilot Study. PMID:35740863
Missense variants causing Wiedemann-Steiner syndrome preferentially occur in the KMT2A-CXXC domain and are accurately classified using AlphaFold2. PMID:35727845
Analysis and pharmacological modulation of senescence in human epithelial stem cells. PMID:35706382
Optogenetic actuator - ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics. PMID:35694820
Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis. PMID:35692536
Age and sex effects on DNA methylation sites linked to genes implicated in severe COVID-19 and SARS-CoV-2 host cell entry. PMID:35679253
Comprehensive analysis of gene expression profiles to identify differential prognostic factors of primary and metastatic breast cancer. PMID:35677896
Single-Cell Transcriptomics-Based Study of Transcriptional Regulatory Features in the Non-Obstructive Azoospermia Testis. PMID:35669193
Transcriptome-Wide Association Studies and Integration Analysis of mRNA Expression Profiles Identify Candidate Genes and Pathways Associated With Ankylosing Spondylitis. PMID:35619696
A N7-Methylguanine-Related Gene Signature Applicable for the Prognosis and Microenvironment of Prostate Cancer. PMID:35602299
NEAT1 can be a diagnostic biomarker in the breast cancer and gastric cancer patients by targeting XIST, hsa-miR-612, and MTRNR2L8: integrated RNA targetome interaction and experimental expression analysis. PMID:35581633
In silico functional and tumor suppressor role of hypothetical protein PCNXL2 with regulation of the Notch signaling pathway. PMID:35539910
Increased expression of NOP14 is associated with improved prognosis due to immune regulation in colorectal cancer. PMID:35473611
Glycation modulates glutamatergic signaling and exacerbates Parkinson's disease-like phenotypes. PMID:35468899
IFITM3 Interacts with the HBV/HDV Receptor NTCP and Modulates Virus Entry and Infection. PMID:35458456
TcdB of Clostridioides difficile Mediates RAS-Dependent Necrosis in Epithelial Cells. PMID:35457076
Sphingolipid Metabolism as a New Predictive Target Correlated with Aging and AD: A Transcriptomic Analysis. PMID:35454332
Combination of Enrichment Using Gene Ontology and Transcriptomic Analysis Revealed Contribution of Interferon Signaling to Severity of COVID-19. PMID:35422859
Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells. PMID:35379199
Sulforaphane suppresses metastasis of triple-negative breast cancer cells by targeting the RAF/MEK/ERK pathway. PMID:35332167
Identifying Environmental Endocrine Disruptors Associated With the Age at Menarche by Integrating a Transcriptome-Wide Association Study With Chemical-Gene-Interaction Analysis. PMID:35282430
Regulatory network-based model to simulate the biochemical regulation of chondrocytes in healthy and osteoarthritic environments. PMID:35264634
High-content analysis of microRNAs involved in the phenotype regulation of vascular smooth muscle cells. PMID:35241704
Protective immune trajectories in early viral containment of non-pneumonic SARS-CoV-2 infection. PMID:35197461
Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs. PMID:35193953
FVIII regulates the molecular profile of endothelial cells: functional impact on the blood barrier and macrophage behavior. PMID:35190870
Efficient link prediction in the protein-protein interaction network using topological information in a generative adversarial network machine learning model. PMID:35183129
Dual RNA Sequencing of Mycobacterium tuberculosis-Infected Human Splenic Macrophages Reveals a Strain-Dependent Host-Pathogen Response to Infection. PMID:35163725
Identification of key candidate genes and pathways associated with colorectal aberrant crypt foci-to-adenoma-to-carcinoma progression. PMID:35154601
Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response. PMID:35111156
Cytoplasmic switch of ARS2 isoforms promotes nonsense-mediated mRNA decay and arsenic sensitivity. PMID:35104878
A New Prospect for the Treatment of Nephrotic Syndrome Based on Network Pharmacology Analysis. PMID:35098155
Skeletal muscle transcriptomics identifies common pathways in nerve crush injury and ageing. PMID:35093178
Neutrophil extracellular traps (NETs) modulate inflammatory profile in obese humans and mice: adipose tissue role on NETs levels. PMID:35066770
Proteomic Response of Deinococcus radiodurans to Short-Term Real Microgravity during Parabolic Flight Reveals Altered Abundance of Proteins Involved in Stress Response and Cell Envelope Functions. PMID:35054415
RNA Sequencing Analysis of Gene Expression by Electroacupuncture in Guinea Pig Gallstone Models. PMID:35035504
Epigenetic scores for the circulating proteome as tools for disease prediction. PMID:35023833
Deep Time Course Proteomics of SARS-CoV- and SARS-CoV-2-Infected Human Lung Epithelial Cells (Calu-3) Reveals Strong Induction of Interferon-Stimulated Gene Expression by SARS-CoV-2 in Contrast to SARS-CoV. PMID:34982558
Analysis of Microarray Data from Medulloblastoma Tissue Samples. PMID:34978688
Ago-RIP Sequencing Identifies New MicroRNA-449a-5p Target Genes Increasing Sorafenib Efficacy in Hepatocellular Carcinoma. PMID:34976171
STXBP6 and B3GNT6 Genes are Associated With Selective IgA Deficiency. PMID:34976003
Oral Selective TLR8 Agonist Selgantolimod Induces Multiple Immune Cell Responses in Humans. PMID:34960669
Transcriptional and Histochemical Signatures of Bone Marrow Mononuclear Cell-Mediated Resolution of Synovitis. PMID:34956173
Fitness Analysis and Transcriptome Profiling Following Repeated Mild Heat Stress of Varying Frequency in Drosophilamelanogaster Females. PMID:34943239
Influence of Silica Exposure for Lung Silicosis Rat. PMID:34938375
Action of carvacrol in Salmonella Typhimurium biofilm: A proteomic study. PMID:34907763
Identification of potential core genes in colorectal carcinoma and key genes in colorectal cancer liver metastasis using bioinformatics analysis. PMID:34907282
LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms. PMID:34903876
Improving Analysis and Annotation of Microarray Data with Protein Interactions. PMID:34902122
Current and Emerging Tools of Computational Biology To Improve the Detoxification of Mycotoxins. PMID:34878810
M-Sec induced by HTLV-1 mediates an efficient viral transmission. PMID:34843591
Clinically Relevant Genes and Proteins Modulated by Tocotrienols in Human Colon Cancer Cell Lines: Systematic Scoping Review. PMID:34836311
Role of FRG1 in predicting the overall survivability in cancers using multivariate based optimal model. PMID:34795329
Integrative COVID-19 biological network inference with probabilistic core decomposition. PMID:34791019
Network based analysis identifies TP53m-BRCA1/2wt-homologous recombination proficient (HRP) population with enhanced susceptibility to Vigil immunotherapy. PMID:34785763
Drug repurposing for coronavirus (SARS-CoV-2) based on gene co-expression network analysis. PMID:34750486
Proximity labeling identifies LOTUS domain proteins that promote the formation of perinuclear germ granules in C. elegans. PMID:34730513
Dysregulation of RNA interference components in COVID-19 patients. PMID:34715923
Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia. PMID:34709177
Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling. PMID:34663829
Metabolic Analysis of Potential Key Genes Associated with Systemic Lupus Erythematosus Using Liquid Chromatography-Mass Spectrometry. PMID:34646335
The Role of E-Cadherin and microRNA on FAK Inhibitor Response in Malignant Pleural Mesothelioma (MPM). PMID:34638565
Proteomics analysis identifies PEA-15 as an endosomal phosphoprotein that regulates α5β1 integrin endocytosis. PMID:34615962
High-quality reference genome of Fasciola gigantica: Insights into the genomic signatures of transposon-mediated evolution and specific parasitic adaption in tropical regions. PMID:34610021
Mechanism of Paeoniae Radix Alba in the Treatment of Non-alcoholic Fatty Liver Disease Based on Sequential Metabolites Identification Approach, Network Pharmacology, and Binding Affinity Measurement. PMID:34604271
The Binary Toxin of Clostridioides difficile Alters the Proteome and Phosphoproteome of HEp-2 Cells. PMID:34594315
A monoallelic SEC23A variant E599K associated with cranio-lenticulo-sutural dysplasia. PMID:34580982
WGCNA Identifies Translational and Proteasome-Ubiquitin Dysfunction in Rett Syndrome. PMID:34576118
Molecular Prognostic Factors for Distant Metastases in Premenopausal Patients with HR+/HER2- Early Breast Cancer. PMID:34575612
Loss of Ubiquitin Carboxy-Terminal Hydrolase L1 Impairs Long-Term Differentiation Competence and Metabolic Regulation in Murine Spermatogonial Stem Cells. PMID:34571914
Proteomic Tools for the Analysis of Cytoskeleton Proteins. PMID:34542864
Towards Building a Quantitative Proteomics Toolbox in Precision Medicine: A Mini-Review. PMID:34512391
Mechanisms of Binding Specificity among bHLH Transcription Factors. PMID:34502060
An early proinflammatory transcriptional response to tau pathology is age-specific and foreshadows reduced tau burden. PMID:34463402
Integrated Bioinformatics Analysis to Identify Alternative Therapeutic Targets for Alzheimer's Disease: Insights from a Synaptic Machinery Perspective. PMID:34414562
Association study of taste preference: Analysis in the Lithuanian population. PMID:34401081
New insights into the proteins interacting with the promoters of silkworm fibroin genes. PMID:34354143
Comprehensive investigation of RNA-sequencing dataset reveals the hub genes and molecular mechanisms of coronavirus disease 2019 acute respiratory distress syndrome. PMID:34350693
Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control. PMID:34338405
Early Functional Impairment in Experimental Glaucoma Is Accompanied by Disruption of the GABAergic System and Inceptive Neuroinflammation. PMID:34299211
The effects of aging on molecular modulators of human embryo implantation. PMID:34278260
Screening and characterization of hypothetical proteins of Plasmodium falciparum as novel vaccine candidates in the fight against malaria using reverse vaccinology. PMID:34269931
Bioinformatics analysis of the role of CXC ligands in the microenvironment of head and neck tumor. PMID:34247149
Screen Key Genes Associated with Distraction-Induced Osteogenesis of Stem Cells Using Bioinformatics Methods. PMID:34204414
Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer. PMID:34198846
Dynamic Host Immune and Transcriptomic Responses to Respiratory Syncytial Virus Infection in a Vaccination-Challenge Mouse Model. PMID:34138405
A bioinformatics approach for identifying potential molecular mechanisms and key genes involved in COVID-19 associated cardiac remodeling. PMID:34131597
In silico analysis of deleterious SNPs of human MTUS1 gene and their impacts on subsequent protein structure and function. PMID:34125870
Contribution of Heptose Metabolites and the cag Pathogenicity Island to the Activation of Monocytes/Macrophages by Helicobacter pylori. PMID:34093525
Identification of core gene in obese type 2 diabetes patients using bioinformatics analysis. PMID:34085602
Mass spectrometry based proteomics for developmental neurobiology in the amphibian Xenopus laevis. PMID:34074530
Computational study of zebrafish immune-targeted microarray data for prediction of preventive drug candidates. PMID:33953878
Genetics of Familial Non-Medullary Thyroid Carcinoma (FNMTC). PMID:33946592
ZC3H4 restricts non-coding transcription in human cells. PMID:33913806
Transcriptome profiles associated with selenium-deficiency-dependent oxidative stress identify potential diagnostic and therapeutic targets in liver cancer cells. PMID:33907497
Integrated Systems Pharmacology and Surface Plasmon Resonance Approaches to Reveal the Synergistic Effect of Multiple Components of Gu-Ben-Ke-Chuan Decoction on Chronic Bronchitis. PMID:33883922
CD25890, a conserved protein that modulates sporulation initiation in Clostridioides difficile. PMID:33846410
Establishing a consensus for the hallmarks of cancer based on gene ontology and pathway annotations. PMID:33823788
Construction of Gene Modules and Analysis of Prognostic Biomarkers for Cervical Cancer by Weighted Gene Co-Expression Network Analysis. PMID:33816217
Effects of Simulated Microgravity on the Proteome and Secretome of the Polyextremotolerant Black Fungus Knufia chersonesos. PMID:33815472
Long-term dynamic compression enhancement TGF-β3-induced chondrogenesis in bovine stem cells: a gene expression analysis. PMID:33743603
Logical modeling of thymus and natural killer lymphocyte differentiation. PMID:33735399
A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models. PMID:33705438
Personalized Profiling Reveals Donor- and Lactation-Specific Trends in the Human Milk Proteome and Peptidome. PMID:33693758
Genomic adaptations to cereal-based diets contribute to mitigate metabolic risk in some human populations of East Asian ancestry. PMID:33664777
OmicLoupe: facilitating biological discovery by interactive exploration of multiple omic datasets and statistical comparisons. PMID:33663372
Benchmarking network-based gene prioritization methods for cerebral small vessel disease. PMID:33634312
A novel DNA methylation-based model that effectively predicts prognosis in hepatocellular carcinoma. PMID:33634306
Label-Free Liquid Chromatography-Mass Spectrometry Proteomic Analysis of Urinary Identification in Diabetic Vascular Dementia in a Han Chinese Population. PMID:33597859
DIscBIO: A User-Friendly Pipeline for Biomarker Discovery in Single-Cell Transcriptomics. PMID:33573289
Exploring the Active Components of Simotang Oral Liquid and Their Potential Mechanism of Action on Gastrointestinal Disorders by Integrating Ultrahigh-Pressure Liquid Chromatography Coupled with Linear Ion Trap-Orbitrap Analysis and Network Pharmacology. PMID:33521474
Is gene expression among women with rheumatoid arthritis dysregulated during a postpartum flare? PMID:33461591
Systematic detection of brain protein-coding genes under positive selection during primate evolution and their roles in cognition. PMID:33441416
m5C RNA Methylation Primarily Affects the ErbB and PI3K-Akt Signaling Pathways in Gastrointestinal Cancer. PMID:33365328
Can a Quantum Walk Tell Which Is Which?A Study of Quantum Walk-Based Graph Similarity. PMID:33267042
Multiple functions of TBCK protein in neurodevelopment disorders and tumors. PMID:33240423
Risk factors and association with severity of keratoconus: the Australian study of Keratoconus. PMID:33200389
Integrated network pharmacology and molecular docking approaches to reveal the synergistic mechanism of multiple components in Venenum Bufonis for ameliorating heart failure. PMID:33194384
Cholesterol-Rich Microdomains Contribute to PAR1 Signaling in Platelets Despite a Weak Localization of the Receptor in These Microdomains. PMID:33138025
Genome-Wide Search for SNP Interactions in GWAS Data: Algorithm, Feasibility, Replication Using Schizophrenia Datasets. PMID:33133133
Kinesin family member 3A inhibits the carcinogenesis of non-small cell lung cancer and prolongs survival. PMID:33123259
Transcriptome analysis of the circadian clock gene BMAL1 deletion with opposite carcinogenic effects. PMID:33111200
Integrated phosphoproteomic and metabolomic profiling reveals perturbed pathways in the hippocampus of gut microbiota dysbiosis mice. PMID:33051451
Keratin 17 regulates nuclear morphology and chromatin organization. PMID:33008845
Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling. PMID:33007944
Transcriptome profiling of Variovorax paradoxus EPS under different growth conditions reveals regulatory and structural novelty in biofilm formation. PMID:32974586
Genomic Signatures of Coevolution between Nonmodel Mammals and Parasitic Roundworms. PMID:32960966
Dysregulated circulating SOCS3 and haptoglobin expression associated with stable coronary artery disease and acute coronary syndrome: An integrated study based on bioinformatics analysis and case-control validation. PMID:32870172
Predicting the most deleterious missense nsSNPs of the protein isoforms of the human HLA-G gene and in silico evaluation of their structural and functional consequences. PMID:32867672
m6A RNA modification modulates PI3K/Akt/mTOR signal pathway in Gastrointestinal Cancer. PMID:32863943
LAITOR4HPC: A text mining pipeline based on HPC for building interaction networks. PMID:32838742
The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells. PMID:32764536
PDCD4 regulates axonal growth by translational repression of neurite growth-related genes and is modulated during nerve injury responses. PMID:32747606
Mapping the Efficacy and Mode of Action of Ethylzingerone [4-(3-Ethoxy-4-Hydroxyphenyl) Butan-2-One] as an Active Agent against Burkholderia Bacteria. PMID:32737133
OmicsON - Integration of omics data with molecular networks and statistical procedures. PMID:32726348
Identification and Functional Analysis of BmNPV-Interacting Proteins From Bombyx mori (Lepidoptera) Larval Midgut Based on Subcellular Protein Levels. PMID:32695093
Global targetome analysis reveals critical role of miR-29a in pancreatic stellate cell mediated regulation of PDAC tumor microenvironment. PMID:32660466
Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways. PMID:32634473
Trnp1 organizes diverse nuclear membrane-less compartments in neural stem cells. PMID:32627867
Multiple Herpes Simplex Virus-1 (HSV-1) Reactivations Induce Protein Oxidative Damage in Mouse Brain: Novel Mechanisms for Alzheimer's Disease Progression. PMID:32610629
Systems chemo-biology analysis of DNA damage response and cell cycle effects induced by coal exposure. PMID:32609278
Proteomics of Sentinel Lymph Nodes in Early Breast Cancer for Identification of Thymidylate Synthase as a Potential Biomarker to Flag Metastasis: A Preliminary Study. PMID:32606973
Deciphering the Novel Target Genes Involved in the Epigenetics of Hepatocellular Carcinoma Using Graph Theory Approach. PMID:32581643
TMT Sample Preparation for Proteomics Facility Submission and Subsequent Data Analysis. PMID:32568242
Another Breaker of the Wall: the Biological Function of the Usp45 Protein of Lactococcus lactis. PMID:32532874
Gene Expression Profiling in Fibromyalgia Indicates an Autoimmune Origin of the Disease and Opens New Avenues for Targeted Therapy. PMID:32532082
Tandem Mass Tag (TMT)-based quantitative proteomics reveals potential targets associated with onset of Sub-clinical Mastitis in cows. PMID:32518370
Analysis of extracellular vesicle miRNA profiles in heart failure. PMID:32485073
Global Distribution and Evolution of Mycobacterium bovis Lineages. PMID:32477295
Positive transcriptional response on inflammation and joint remodelling influenced by physical exercise in proteoglycan-induced arthritis: An animal study. PMID:32435454
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits. PMID:32400009
Loss of wild-type p53 promotes mutant p53-driven metastasis through acquisition of survival and tumor-initiating properties. PMID:32393735
Genomic competition for noise reduction shaped evolutionary landscape of mir-4673. PMID:32376854
Proteomic variations after short-term heat shock treatment reveal differentially expressed proteins involved in early microspore embryogenesis in cabbage (Brassica oleracea). PMID:32337101
Target Identification Using Homopharma and Network-Based Methods for Predicting Compounds Against Dengue Virus-Infected Cells. PMID:32325755
Hepatitis B Virus Core Particles Containing a Conserved Region of the G Protein Combined with Interleukin-35 Protected Mice against Respiratory Syncytial Virus Infection without Vaccine-Enhanced Immunopathology. PMID:32321805
Network Systems Pharmacology-Based Mechanism Study on the Beneficial Effects of Vitamin D against Psychosis in Alzheimer's Disease. PMID:32273551
A comprehensive analysis of sialolith proteins and the clinical implications. PMID:32265614
WeiBI (web-based platform): Enriching integrated interaction network with increased coverage and functional proteins from genome-wide experimental OMICS data. PMID:32221380
CAncer bioMarker Prediction Pipeline (CAMPP)-A standardized framework for the analysis of quantitative biological data. PMID:32176694
Overall survival prediction of non-small cell lung cancer by integrating microarray and clinical data with deep learning. PMID:32170141
Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells. PMID:32170109
Network hub-node prioritization of gene regulation with intra-network association. PMID:32164570
Proteomic profiling of vetiver grass (Chrysopogon zizanioides) under 2,4,6-trinitrotoluene (TNT) stress. PMID:32158981
TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis. PMID:32101751
Secretome Analysis of Mouse Dendritic Cells Interacting with a Probiotic Strain of Lactobacillus gasseri. PMID:32093322
Heterogeneous Multi-Layered Network Model for Omics Data Integration and Analysis. PMID:32063919
Transcriptomic Profiles of Zymomonas mobilis 8b to Furfural Acute and Long-Term Stress in Both Glucose and Xylose Conditions. PMID:32038596
In Silico Strategies in Tuberculosis Drug Discovery. PMID:32033144
Differential impacts of late gestational over-and undernutrition on adipose tissue traits and associated visceral obesity risk upon exposure to a postnatal high-fat diet in adolescent sheep. PMID:32026612
Comprehensive understanding of B7 family in gastric cancer: expression profile, association with clinicopathological parameters and downstream targets. PMID:32025206
Protein Oxidative Damage in UV-Related Skin Cancer and Dysplastic Lesions Contributes to Neoplastic Promotion and Progression. PMID:31906275
Genome sequencing of Mycobacterium pinnipedii strains: genetic characterization and evidence of superinfection in a South American sea lion (Otaria flavescens). PMID:31888476
Nuclear factor erythroid 2 - related factor 2 and its relationship with cellular response in nickel exposure: a systems biology analysis. PMID:31852525
Effect of cadmium on essential metals and their impact on lipid metabolism in Saccharomyces cerevisiae. PMID:31823289
Styrene maleic acid recovers proteins from mammalian cells and tissues while avoiding significant cell death. PMID:31767876
An epigenetic screening determines BET proteins as targets to suppress self-renewal and tumorigenicity in canine mammary cancer cells. PMID:31758045
Characterization of Matricellular Protein Expression Signatures in Mechanistically Diverse Mouse Models of Kidney Injury. PMID:31723159
Quantitative Proteomics Reveal Peroxiredoxin Perturbation Upon Persistent Lymphocytic Choriomeningitis Virus Infection in Human Cells. PMID:31708904
A New Strategy for Identifying Mechanisms of Drug-drug Interaction Using Transcriptome Analysis: Compound Kushen Injection as a Proof of Principle. PMID:31685921
Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast. PMID:31676685
Cerebrospinal Fluid Proteomics For Identification Of α2-Macroglobulin As A Potential Biomarker To Monitor Pharmacological Therapeutic Efficacy In Dopamine Dictated Disease States Of Parkinson's Disease And Schizophrenia. PMID:31632033
Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion. PMID:31615920
Broad Phenotypes of Disorders/Differences of Sex Development in MAMLD1 Patients Through Oligogenic Disease. PMID:31555317
A Novel TTC19 Mutation in a Patient With Neurological, Psychological, and Gastrointestinal Impairment. PMID:31551910
Deciphering structure, function and mechanism of lysine acetyltransferase HBO1 in protein acetylation, transcription regulation, DNA replication and its oncogenic properties in cancer. PMID:31535175
Reticulocyte and red blood cell deformation triggers specific phosphorylation events. PMID:31506283
A Survey of Gene Prioritization Tools for Mendelian and Complex Human Diseases. PMID:31494632
Long Non-Coding RNAs Modulate Sjögren's Syndrome Associated Gene Expression and Are Involved in the Pathogenesis of the Disease. PMID:31480511
Transcriptome and Network Dissection of Microsatellite Stable and Highly Instable Colorectal Cancer. PMID:31450919
Association of Cyclin Dependent Kinase 10 and Transcription Factor 2 during Human Corneal Epithelial Wound Healing in vitro model. PMID:31413335
Evaluation of α-synuclein and apolipoprotein E as potential biomarkers in cerebrospinal fluid to monitor pharmacotherapeutic efficacy in dopamine dictated disease states of Parkinson's disease and schizophrenia. PMID:31410011
Long Non-Coding RNAs Target Pathogenetically Relevant Genes and Pathways in Rheumatoid Arthritis. PMID:31382516
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection With Transcriptome Analysis. PMID:31380274
Data on hyper-activation of GPVI signalling in obese patients: Towards the identification of novel antiplatelet targets in obesity. PMID:31372431
Omics Approaches in Pancreatic Adenocarcinoma. PMID:31349663
Identification of differentially expressed genes in hip cartilage with femoral head necrosis, based on genome‑wide expression profiles. PMID:31322206
mTORC1/AMPK responses define a core gene set for developmental cell fate switching. PMID:31319820
Stress-induced Changes in the S-palmitoylation and S-nitrosylation of Synaptic Proteins. PMID:31311849
Circular RNA Signature in Hepatocellular Carcinoma. PMID:31293639
Examining the biomarkers and molecular mechanisms of medulloblastoma based on bioinformatics analysis. PMID:31289514
TLR4 participates in the transmission of ethanol-induced neuroinflammation via astrocyte-derived extracellular vesicles. PMID:31272469
Identifying miRNA-mRNA Pairs and Novel miRNAs from Hepatocelluar Carcinoma miRNomes and TCGA Database. PMID:31258761
Carriage of Shiga toxin phage profoundly affects Escherichia coli gene expression and carbon source utilization. PMID:31208335
Using genetics to understand biology. PMID:31189902
Overexpression of NCAPH is upregulated and predicts a poor prognosis in prostate cancer. PMID:31186803
Nerve Growth Factor Induces Proliferation and Aggressiveness In Prostate Cancer Cells. PMID:31174415
Immunomodulatory Effects and Induction of Apoptosis by Different Molecular Weight Chitosan Oligosaccharides in Head Kidney Macrophages From Blunt Snout Bream (Megalobrama amblycephala). PMID:31156612
Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway. PMID:31147963
3D gelatin-chitosan hybrid hydrogels combined with human platelet lysate highly support human mesenchymal stem cell proliferation and osteogenic differentiation. PMID:31105928
Proteomic Profiling of Human Prostate Cancer-associated Fibroblasts (CAF) Reveals LOXL2-dependent Regulation of the Tumor Microenvironment. PMID:31061140
Cryptochrome deletion in p53 mutant mice enhances apoptotic and anti-tumorigenic responses to UV damage at the transcriptome level. PMID:31044344
Gnal haploinsufficiency causes genomic instability and increased sensitivity to haloperidol. PMID:31034808
Understanding the regulation of overwintering diapause molecular mechanisms in Culex pipiens pallens through comparative proteomics. PMID:31019237
Proteomics of intracellular Salmonella enterica reveals roles of Salmonella pathogenicity island 2 in metabolism and antioxidant defense. PMID:31009521
Knockdown of BmTCP-1β Delays BmNPV Infection in vitro. PMID:30967853
Comprehensive analysis of differentially expressed profiles and reconstruction of a competing endogenous RNA network in papillary renal cell carcinoma. PMID:30957192
Glycolytic flux in Saccharomyces cerevisiae is dependent on RNA polymerase III and its negative regulator Maf1. PMID:30885983
Cellular response to small molecules that selectively stall protein synthesis by the ribosome. PMID:30875366
Analyzing bioactive effects of the minor hop compound xanthohumol C on human breast cancer cells using quantitative proteomics. PMID:30875365
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme. PMID:30867843
In Systemic Sclerosis, a Unique Long Non Coding RNA Regulates Genes and Pathways Involved in the Three Main Features of the Disease (Vasculopathy, Fibrosis and Autoimmunity) and in Carcinogenesis. PMID:30866419
Differential gene expression induced by Verteporfin in endometrial cancer cells. PMID:30846786
AAV9-TAZ Gene Replacement Ameliorates Cardiac TMT Proteomic Profiles in a Mouse Model of Barth Syndrome. PMID:30788385
Autophagy and Apoptosis Specific Knowledgebases-guided Systems Pharmacology Drug Research. PMID:30727895
Genes encoding SATB2-interacting proteins in adult cerebral cortex contribute to human cognitive ability. PMID:30726206
Linking genetic, metabolic, and phenotypic diversity among Saccharomyces cerevisiae strains using multi-omics associations. PMID:30715293
The translational regulator FMRP controls lipid and glucose metabolism in mice and humans. PMID:30686771
Gene Expression Patterns Analysis in the Supraspinatus Muscle after a Rotator Cuff Tear in a Mouse Model. PMID:30671462
Interleukin 4 induces rapid mucin transport, increases mucus thickness and quality and decreases colitis and Citrobacter rodentium in contact with epithelial cells. PMID:30665337
GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: Elucidating potential anti-atherothrombotic targets in obesity. PMID:30658193
Proteomic Analysis of the Responses of Candida albicans during Infection of Galleria mellonella Larvae. PMID:30641883
Evidence for an association of interferon gene variants with sudden infant death syndrome. PMID:30617847
Protective Effect of Salidroside Against Diabetic Kidney Disease Through Inhibiting BIM-Mediated Apoptosis of Proximal Renal Tubular Cells in Rats. PMID:30564128
Arylsulfonamide 64B Inhibits Hypoxia/HIF-Induced Expression of c-Met and CXCR4 and Reduces Primary Tumor Growth and Metastasis of Uveal Melanoma. PMID:30563937
Identifying mouse developmental essential genes using machine learning. PMID:30563825
Identification and Analysis of Rice Yield-Related Candidate Genes by Walking on the Functional Network. PMID:30524460
Derivation and Validation of the Potential Core Genes in Pancreatic Cancer for Tumor-Stroma Crosstalk. PMID:30519576
Cardiac contractility modulation: mechanisms of action in heart failure with reduced ejection fraction and beyond. PMID:30485591
Haploinsufficiency of the intellectual disability gene SETD5 disturbs developmental gene expression and cognition. PMID:30455454
Elevation in Cell Cycle and Protein Metabolism Gene Transcription in Inactive Colonic Tissue From Icelandic Patients With Ulcerative Colitis. PMID:30452647
Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN. PMID:30425250
Role of Overexpressed Transcription Factor FOXO1 in Fatal Cardiovascular Septal Defects in Patau Syndrome: Molecular and Therapeutic Strategies. PMID:30423812
Combined multivariate analysis and machine learning reveals a predictive module of metabolic stress response in Arabidopsis thaliana. PMID:30387490
Cold plasma effect on the proteome of Pseudomonas aeruginosa - Role for bacterioferritin. PMID:30365553
Substrate Specificity Analysis of Dihydrofolate/Dihydromethanopterin Reductase Homologs in Methylotrophic α-Proteobacteria. PMID:30364315
Evaluation of Serum Apolipoprotein E as a Potential Biomarker for Pharmacological Therapeutic Efficacy Monitoring in Dopamine Dictated Disease Spectrum of Schizophrenia and Parkinson's disease: A Preliminary Study. PMID:30327579
Oxidant stress induction and signalling in xenografted (human breast cancer-tissues) plus estradiol treated or N-ethyl-N-nitrosourea treated female rats via altered estrogen sulfotransferase (rSULT1E1) expressions and SOD1/catalase regulations. PMID:30315444
Discovering Genetic Factors for psoriasis through exhaustively searching for significant second order SNP-SNP interactions. PMID:30315195
Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice. PMID:30273559
Single-Run Mass Spectrometry Analysis Provides Deep Insight into E. coli Proteome. PMID:30259409
Synthesis and mechanistic studies of quinolin-chlorobenzothioate derivatives with proteasome inhibitory activity in pancreatic cancer cell lines. PMID:30253345
Knockout of the Hmt1p Arginine Methyltransferase in Saccharomyces cerevisiae Leads to the Dysregulation of Phosphate-associated Genes and Processes. PMID:30206180
DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy. PMID:30196736
The Xenopus animal cap transcriptome: building a mucociliary epithelium. PMID:30165493
Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study. PMID:30134812
Bioinformatics Analysis of Transcriptomic Data Reveals Refined Functional Networks for the Self-Renewal of Mouse Spermatogonial Stem Cells. PMID:30123288
Dynamical Analysis of the Regulatory Network Controlling Natural Killer Cells Differentiation. PMID:30116200
Reconstruction of the Protein-Protein Interaction Network for Protein Complexes Identification by Walking on the Protein Pair Fingerprints Similarity Network. PMID:30087694
Whole Cell Cross-Linking to Discover Host-Microbe Protein Cognate Receptor/Ligand Pairs. PMID:30072965
Long Non-Coding RNAs Play a Role in the Pathogenesis of Psoriatic Arthritis by Regulating MicroRNAs and Genes Involved in Inflammation and Metabolic Syndrome. PMID:30061880
Annexin A2 binds to vimentin and contributes to porcine reproductive and respiratory syndrome virus multiplication. PMID:30053894
Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia. PMID:30038221
Disruption of microglia histone acetylation and protein pathways in mice exhibiting inflammation-associated depression-like symptoms. PMID:30005281
Identification of differential modules in ankylosing spondylitis using systemic module inference and the attract method. PMID:29977361
High Expression of CD200 and CD200R1 Distinguishes Stem and Progenitor Cell Populations within Mammary Repopulating Units. PMID:29937142
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes. PMID:29931111
RNA-Seq based transcriptome of whole blood from immunocompetent pigs (Sus scrofa) experimentally infected with Mycoplasma suis strain Illinois. PMID:29914581
Effect of temperature on Burkholderia pseudomallei growth, proteomic changes, motility and resistance to stress environments. PMID:29907803
Linkage analysis and whole exome sequencing identify a novel candidate gene in a Dutch multiple sclerosis family. PMID:29873607
Transcriptomic analysis of neuregulin-1 regulated genes following ischemic stroke by computational identification of promoter binding sites: A role for the ETS-1 transcription factor. PMID:29856744
Gene Expression Profiling in Behcet's Disease Indicates an Autoimmune Component in the Pathogenesis of the Disease and Opens New Avenues for Targeted Therapy. PMID:29850627
In Silico Analysis of Natural Resistance-Associated Macrophage Protein (NRAMP) Family of Transporters in Rice. PMID:29785641
Genomics and Epigenomics of Congenital Heart Defects: Expert Review and Lessons Learned in Africa. PMID:29762087
Bioinformatics-based identification of potential microRNA biomarkers in frequent and non-frequent exacerbators of COPD. PMID:29713155
The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature. PMID:29681787
Genome-Wide Analyses of Calcium Sensors Reveal Their Involvement in Drought Stress Response and Storage Roots Deterioration after Harvest in Cassava. PMID:29671773
Systematic Evaluation of Molecular Networks for Discovery of Disease Genes. PMID:29605183
Gene Profiling in Patients with Systemic Sclerosis Reveals the Presence of Oncogenic Gene Signatures. PMID:29559981
ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling. PMID:29472497
Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD). PMID:29401581
Scuba: scalable kernel-based gene prioritization. PMID:29370760
Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC). PMID:29363612
Commensal Homeostasis of Gut Microbiota-Host for the Impact of Obesity. PMID:29358923
Identification and Comparison of Differentiation-Related Proteins in Hepatocellular Carcinoma Tissues by Proteomics. PMID:29332450
Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation. PMID:29330507
Integrative approach using liver and duodenum RNA-Seq data identifies candidate genes and pathways associated with feed efficiency in pigs. PMID:29323241
Discovery and Longitudinal Evaluation of Candidate Biomarkers for Ischaemic Stroke by Mass Spectrometry-Based Proteomics. PMID:29308009
Global mapping of transcription factor motifs in human aging. PMID:29293662
PECAplus: statistical analysis of time-dependent regulatory changes in dynamic single-omics and dual-omics experiments. PMID:29263799
Gene expression in the chicken caecum is dependent on microbiota composition. PMID:29202873
Inference of differentiation time for single cell transcriptomes using cell population reference data. PMID:29187729
Vanillic acid from Actinidia deliciosa impedes virulence in Serratia marcescens by affecting S-layer, flagellin and fatty acid biosynthesis proteins. PMID:29180790
5D proteomic approach for the biomarker search in plasma: Acute myeloid leukaemia as a case study. PMID:29180721
The Diversity of REcent and Ancient huMan (DREAM): A New Microarray for Genetic Anthropology and Genealogy, Forensics, and Personalized Medicine. PMID:29165562
Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice. PMID:29163474
ProteomicsDB. PMID:29106664
Identification of the PAK4 interactome reveals PAK4 phosphorylation of N-WASP and promotion of Arp2/3-dependent actin polymerization. PMID:29100370
The Production of Curli Amyloid Fibers Is Deeply Integrated into the Biology of Escherichia coli. PMID:29088115
Identification of key pathways and genes with aberrant methylation in prostate cancer using bioinformatics analysis. PMID:29066912
Computational Analysis of High Risk Missense Variant in Human UTY Gene: A Candidate Gene of AZFa Sub-region. PMID:29062794
Coupling chemosensory array formation and localization. PMID:29058677
Network-based analysis of the molecular mechanisms of multiple myeloma and monoclonal gammopathy of undetermined significance. PMID:28943924
Nε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains: Proteins Involved in Bioenergetics, Virulence, and Antimicrobial Resistance Are Acetylated. PMID:28920697
Screening critical genes associated with malignant glioma using bioinformatics analysis. PMID:28901452
Predicted networks of protein-protein interactions in Stegodyphus mimosarum by cross-species comparisons. PMID:28893204
Multiple network-constrained regressions expand insights into influenza vaccination responses. PMID:28881994
Immune system deregulation in hypertensive patients chronically RAS suppressed developing albuminuria. PMID:28827575
Interrogating Patient-level Genomics and Mouse Phenomics towards Understanding Cytokines in Colorectal Cancer Metastasis. PMID:28815134
The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation. PMID:28811474
PhosphoPredict: A bioinformatics tool for prediction of human kinase-specific phosphorylation substrates and sites by integrating heterogeneous feature selection. PMID:28761071
Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice. PMID:28728022
MINERVA-a platform for visualization and curation of molecular interaction networks. PMID:28725475
Comparative proteome analysis for identification of differentially abundant proteins in SIDS. PMID:28717962
A wellness study of 108 individuals using personal, dense, dynamic data clouds. PMID:28714965
The Impact of Gut Microbiota on Gender-Specific Differences in Immunity. PMID:28713378
Germline Chd8 haploinsufficiency alters brain development in mouse. PMID:28671691
Methylation differences reveal heterogeneity in preterm pathophysiology: results from bipartite network analyses. PMID:28665803
Potential lung carcinogenicity induced by chronic exposure to PM2.5 in the rat. PMID:28656580
Establishment of a 3D cell culture model of primary bovine mammary epithelial cells extracted from fresh milk. PMID:28643224
Exposure of Induced Pluripotent Stem Cell-Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell-Like Phenotypes. PMID:28628273
Comparative proteomic analysis of eggplant (Solanum melongena L.) heterostylous pistil development. PMID:28586360
Weighted gene co-expression network analysis of gene modules for the prognosis of esophageal cancer. PMID:28585144
A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data. PMID:28569218
Urinary exosomes reveal protein signatures in hypertensive patients with albuminuria. PMID:28562335
Gene co-expression network reveals shared modules predictive of stage and grade in serous ovarian cancers. PMID:28562334
Pregnancy-induced gene expression changes in vivo among women with rheumatoid arthritis: a pilot study. PMID:28545501
Serum depletion induces changes in protein expression in the trophoblast-derived cell line HTR-8/SVneo. PMID:28536624
SCENERY: a web application for (causal) network reconstruction from cytometry data. PMID:28525568
Determination of Genes Related to Uveitis by Utilization of the Random Walk with Restart Algorithm on a Protein-Protein Interaction Network. PMID:28505077
Different phosphoisoforms of RNA polymerase II engage the Rtt103 termination factor in a structurally analogous manner. PMID:28465432
Hyper-phosphorylation of Sequestosome-1 Distinguishes Resistance to Cisplatin in Patient Derived High Grade Serous Ovarian Cancer Cells. PMID:28455291
Gene Expression Analysis before and after Treatment with Adalimumab in Patients with Ankylosing Spondylitis Identifies Molecular Pathways Associated with Response to Therapy. PMID:28441778
Proteomic profiling of HBV infected liver biopsies with different fibrotic stages. PMID:28439208
Respiratory status determines the effect of emodin on cell viability. PMID:28415582
The Glial Cell-Derived Neurotrophic Factor (GDNF)-responsive Phosphoprotein Landscape Identifies Raptor Phosphorylation Required for Spermatogonial Progenitor Cell Proliferation. PMID:28408662
ESCDL-1, a new cell line derived from chicken embryonic stem cells, supports efficient replication of Mardiviruses. PMID:28406989
Knockdown of stem cell regulator Oct4A in ovarian cancer reveals cellular reprogramming associated with key regulators of cytoskeleton-extracellular matrix remodelling. PMID:28406185
Recognition memory-induced gene expression in the perirhinal cortex: A transcriptomic analysis. PMID:28389337
Comparative Subcellular Proteomics Analysis of Susceptible and Near-isogenic Resistant Bombyx mori (Lepidoptera) Larval Midgut Response to BmNPV infection. PMID:28361957
Mitochondrial proteomics of the acetic acid - induced programmed cell death response in a highly tolerant Zygosaccharomyces bailii - derived hybrid strain. PMID:28357336
Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats. PMID:28349193
Flightless-I governs cell fate by recruiting the SUMO isopeptidase SENP3 to distinct HOX genes. PMID:28344658
Understanding the conservation patterns and molecular phylogenetics of human death receptors family through computational biology. PMID:28324447
Comprehensive discovery of subsample gene expression components by information explanation: therapeutic implications in cancer. PMID:28292312
Functional Diversity of Transcriptional Regulators in the Cyanobacterium Synechocystis sp. PCC 6803. PMID:28270809
Pathway Cross-Talk Analysis in Detecting Significant Pathways in Barrett's Esophagus Patients. PMID:28263955
A three-way approach for protein function classification. PMID:28234929
Genome Wide In silico Analysis of the Mismatch Repair Components of Plasmodium falciparum and Their Comparison with Human Host. PMID:28232818
Effect of myeloid differentiation primary response gene 88 on expression profiles of genes during the development and progression of Helicobacter-induced gastric cancer. PMID:28201999
GWAS of self-reported mosquito bite size, itch intensity and attractiveness to mosquitoes implicates immune-related predisposition loci. PMID:28199695
Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. PMID:28198360
Whole-exome sequencing of individuals from an isolated population implicates rare risk variants in bipolar disorder. PMID:28195573
Effects of ErbB2 Overexpression on the Proteome and ErbB Ligand-specific Phosphosignaling in Mammary Luminal Epithelial Cells. PMID:28174229
The Transcription Profile Unveils the Cardioprotective Effect of Aspalathin against Lipid Toxicity in an In Vitro H9c2 Model. PMID:28146135
Skewing in Arabidopsis roots involves disparate environmental signaling pathways. PMID:28143395
Integrative Variation Analysis Reveals that a Complex Genotype May Specify Phenotype in Siblings with Syndromic Autism Spectrum Disorder. PMID:28118382
MIF/CD74 axis is a target for novel therapies in colon carcinomatosis. PMID:28114961
Zika virus disrupts molecular fingerprinting of human neurospheres. PMID:28112162
A Periplasmic Polymer Curves Vibrio cholerae and Promotes Pathogenesis. PMID:28086090
Systematic Analysis of Transcriptional and Post-transcriptional Regulation of Metabolism in Yeast. PMID:28072816
Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea. PMID:28053595
Comprehensive Metaproteomic Analyses of Urine in the Presence and Absence of Neutrophil-Associated Inflammation in the Urinary Tract. PMID:28042331
DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds. PMID:28032149
The role of prostate tumor overexpressed 1 in cancer progression. PMID:28029646
Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1. PMID:28027307
Prediction of key genes and miRNAs responsible for loss of muscle force in patients during an acute exacerbation of chronic obstructive pulmonary disease. PMID:28025995
A Meta-Analysis Based Method for Prioritizing Candidate Genes Involved in a Pre-specific Function. PMID:28018423
A Stromal Immune Module Correlated with the Response to Neoadjuvant Chemotherapy, Prognosis and Lymphocyte Infiltration in HER2-Positive Breast Carcinoma Is Inversely Correlated with Hormonal Pathways. PMID:28005906
Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis. PMID:27942596
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible. PMID:27924014
PCAN: phenotype consensus analysis to support disease-gene association. PMID:27923364
Finding Potential Therapeutic Targets against Shigella flexneri through Proteome Exploration. PMID:27920755
Early Molecular Stratification of High-risk Primary Biliary Cholangitis. PMID:27913155
Phylogenetic analysis of basic helix-loop-helix transcription factors in the genome of a typical human-disease vector. PMID:27904685
Systematic tracking of disrupted modules identifies significant genes and pathways in hepatocellular carcinoma. PMID:27899995
The Genome Conformation As an Integrator of Multi-Omic Data: The Example of Damage Spreading in Cancer. PMID:27895661
Computational Discovery of Putative Leads for Drug Repositioning through Drug-Target Interaction Prediction. PMID:27893735
Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues. PMID:27889451
HPV16 integration probably contributes to cervical oncogenesis through interrupting tumor suppressor genes and inducing chromosome instability. PMID:27884161
Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity. PMID:27874830
Transcriptome analysis reveals manifold mechanisms of cyst development in ADPKD. PMID:27871310
Identification of clinically predictive metagenes that encode components of a network coupling cell shape to transcription by image-omics. PMID:27864353
Identification of an Efficient Gene Expression Panel for Glioblastoma Classification. PMID:27855170
Regulatory Architecture of Gene Expression Variation in the Threespine Stickleback Gasterosteus aculeatus. PMID:27836907
Investigating genetic characteristics of hepatitis B virus-associated and -non-associated hepatocellular carcinoma. PMID:27834158
Potential molecular characteristics in situ in response to repetitive UVB irradiation. PMID:27829444
Control of mitochondrial function and cell growth by the atypical cadherin Fat1. PMID:27828948
Analysis of Gene Expression in an Inbred Line of Soft-Shell Clams (Mya arenaria) Displaying Growth Heterosis: Regulation of Structural Genes and the NOD2 Pathway. PMID:27822466
Integrative omics connects N-glycoproteome-wide alterations with pathways and regulatory events in induced pluripotent stem cells. PMID:27808266
Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome. PMID:27798693
Rare Variants in Neurodegeneration Associated Genes Revealed by Targeted Panel Sequencing in a German ALS Cohort. PMID:27790088
A graphical model approach visualizes regulatory relationships between genome-wide transcription factor binding profiles. PMID:27780826
Proteomic analysis reveals diverse proline hydroxylation-mediated oxygen-sensing cellular pathways in cancer cells. PMID:27764789
Distinct Cell Stress Responses Induced by ATP Restriction in Quiescent Human Fibroblasts. PMID:27757122
Label-free LC-MS/MS shotgun proteomics to investigate the anti-inflammatory effect of rCC16. PMID:27748820
Epigenetics in Schizophrenia: A Pilot Study of Global DNA Methylation in Different Brain Regions Associated with Higher Cognitive Functions. PMID:27746755
Exploring the interactions of the RAS family in the human protein network and their potential implications in RAS-directed therapies. PMID:27713118
Network analysis of mitonuclear GWAS reveals functional networks and tissue expression profiles of disease-associated genes. PMID:27704213
The ubiquitin ligase TRIM27 functions as a host restriction factor antagonized by Mycobacterium tuberculosis PtpA during mycobacterial infection. PMID:27698396
CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages. PMID:27670879
Subclinical Pregnancy Toxemia-Induced Gene Expression Changes in Ovine Placenta and Uterus. PMID:27626035
Pathway Analysis Incorporating Protein-Protein Interaction Networks Identified Candidate Pathways for the Seven Common Diseases. PMID:27622767
HMGB4 is expressed by neuronal cells and affects the expression of genes involved in neural differentiation. PMID:27608812
Role of miRNAs in Epicardial Adipose Tissue in CAD Patients with T2DM. PMID:27597954
Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells. PMID:27589771
Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer. PMID:27566577
Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks. PMID:27553489
A proteomic evaluation of urinary changes associated with cardiopulmonary bypass. PMID:27528862
Libby amphibole-induced mesothelial cell autoantibodies bind to surface plasminogen and alter collagen matrix remodeling. PMID:27519611
Human Sirtuin 2 Localization, Transient Interactions, and Impact on the Proteome Point to Its Role in Intracellular Trafficking. PMID:27503897
A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. PMID:27501013
A Proteomic Investigation of Hepatic Resistance to Ascaris in a Murine Model. PMID:27490109
Proteomic and Transcriptomic Analyses of Swine Pathogen Erysipelothrix rhusiopathiae Reveal Virulence Repertoire. PMID:27479071
A PII-Like Protein Regulated by Bicarbonate: Structural and Biochemical Studies of the Carboxysome-Associated CPII Protein. PMID:27464895
Drosophila Ringmaker regulates microtubule stabilization and axonal extension during embryonic development. PMID:27422099
Identification of Pathways in Liver Repair Potentially Targeted by Secretory Proteins from Human Mesenchymal Stem Cells. PMID:27409608
Monoethylhexyl Phthalate Elicits an Inflammatory Response in Adipocytes Characterized by Alterations in Lipid and Cytokine Pathways. PMID:27384973
Gene-Expression Profiling Suggests Impaired Signaling via the Interferon Pathway in Cstb-/- Microglia. PMID:27355630
Protein-Protein Interactions Suggest Novel Activities of Human Cytomegalovirus Tegument Protein pUL103. PMID:27334581
Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function. PMID:27332732
In silico analysis of deleterious single nucleotide polymorphisms in human BUB1 mitotic checkpoint serine/threonine kinase B gene. PMID:27331020
Comparative proteomic study of Arabidopsis mutants mpk4 and mpk6. PMID:27324189
Identification of CD20, ECM, and ITGA as Biomarkers for Osteosarcoma by Integrating Transcriptome Analysis. PMID:27314445
A statistical method for detecting differentially expressed SNVs based on next-generation RNA-seq data. PMID:27276420
Review on Graph Clustering and Subgraph Similarity Based Analysis of Neurological Disorders. PMID:27258269
The Use of Protein-Protein Interactions for the Analysis of the Associations between PM2.5 and Some Diseases. PMID:27243032
EP300 Protects from Light-Induced Retinopathy in Zebrafish. PMID:27242532
An atlas of gene expression and gene co-regulation in the human retina. PMID:27235414
Crowdsourcing the nodulation gene network discovery environment. PMID:27230384
Networks of Host Factors that Interact with NS1 Protein of Influenza A Virus. PMID:27199973
The Proteasome Stress Regulon Is Controlled by a Pair of NAC Transcription Factors in Arabidopsis. PMID:27194708
Low expression of leptin and its association with breast cancer: A transcriptomic study. PMID:27177292
Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa. PMID:27167126
DNA Microarray Analysis in Screening Features of Genes Involved in Spinal Cord Injury. PMID:27160807
Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics. PMID:27134283
HEY1 functions are regulated by its phosphorylation at Ser-68. PMID:27129302
An examination of the regulatory mechanism of Pxdn mutation-induced eye disorders using microarray analysis. PMID:27121343
Genome-wide non-CpG methylation of the host genome during M. tuberculosis infection. PMID:27112593
Proteomic dissection of LPS-inducible, PHF8-dependent secretome reveals novel roles of PHF8 in TLR4-induced acute inflammation and T cell proliferation. PMID:27112199
Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression. PMID:27096627
Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance. PMID:27095270
The Atlantic salmon genome provides insights into rediploidization. PMID:27088604
Impact of gut microbiota on the fly's germ line. PMID:27080728
A Quantitative Approach to Analyzing Genome Reductive Evolution Using Protein-Protein Interaction Networks: A Case Study of Mycobacterium leprae. PMID:27066064
A Novel Prioritization Method in Identifying Recurrent Venous Thromboembolism-Related Genes. PMID:27050193
Evidence for embryonic stem-like signature and epithelial-mesenchymal transition features in the spheroid cells derived from lung adenocarcinoma. PMID:27048287
Defining Molecular Basis for Longevity Traits in Natural Yeast Isolates. PMID:27030810
Large-Scale, Ion-Current-Based Proteomic Investigation of the Rat Striatal Proteome in a Model of Short- and Long-Term Cocaine Withdrawal. PMID:27018876
Systems psychopharmacology: A network approach to developing novel therapies. PMID:27014599
HNdb: an integrated database of gene and protein information on head and neck squamous cell carcinoma. PMID:27013077
ABCE1 is essential for S phase progression in human cells. PMID:26985706
Genes with high penetrance for syndromic and non-syndromic autism typically function within the nucleus and regulate gene expression. PMID:26985359
Microglia-Derived Cytokines/Chemokines Are Involved in the Enhancement of LPS-Induced Loss of Nigrostriatal Dopaminergic Neurons in DJ-1 Knockout Mice. PMID:26982707
Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network. PMID:26974125
A Quantitative Proteomic Analysis of Urine from Gamma-Irradiated Non-Human Primates. PMID:26962295
Insulin receptor substrate 1 is a substrate of the Pim protein kinases. PMID:26956053
Biological network-driven gene selection identifies a stromal immune module as a key determinant of triple-negative breast carcinoma prognosis. PMID:26942074
The Role of CD44 and ERM Proteins in Expression and Functionality of P-glycoprotein in Breast Cancer Cells. PMID:26938523
NecroX-5 protects mitochondrial oxidative phosphorylation capacity and preserves PGC1α expression levels during hypoxia/reoxygenation injury. PMID:26937217
Time-resolved proteomic analysis of quorum sensing in Vibrio harveyi. PMID:26925210
The human DNA ends proteome uncovers an unexpected entanglement of functional pathways. PMID:26921407
Modelling local gene networks increases power to detect trans-acting genetic effects on gene expression. PMID:26911988
Nine susceptibility loci for hepatitis B virus-related hepatocellular carcinoma identified by a pilot two-stage genome-wide association study. PMID:26870257
DNA methyltransferase 1, 3a, and 3b expression in hepatitis C associated human hepatocellular carcinoma and their clinicopathological association. PMID:26850594
Toward Repurposing Metformin as a Precision Anti-Cancer Therapy Using Structural Systems Pharmacology. PMID:26841718
A Genetic Risk Score Is Associated with Weight Loss Following Roux-en Y Gastric Bypass Surgery. PMID:26832135
A panel of glycoproteins as candidate biomarkers for early diagnosis and treatment evaluation of B-cell acute lymphoblastic leukemia. PMID:26823978
Network-Based Analysis of eQTL Data to Prioritize Driver Mutations. PMID:26802430
Screening feature genes of astrocytoma using a combined method of microarray gene expression profiling and bioinformatics analysis. PMID:26770395
Differential Expression of Proteins Associated with the Hair Follicle Cycle - Proteomics and Bioinformatics Analyses. PMID:26752403
Exome Sequencing Analysis in Severe, Early-Onset Chronic Obstructive Pulmonary Disease. PMID:26736064
T-bet as a key regulator of mucosal immunity. PMID:26726991
HitWalker2: visual analytics for precision medicine and beyond. PMID:26708334
Putative alternative polyadenylation (APA) events in the early interaction of Salmonella enterica Typhimurium and human host cells. PMID:26697380
Prediction of Druggable Proteins Using Machine Learning and Systems Biology: A Mini-Review. PMID:26696900
Predictive Modeling of Drug Treatment in the Area of Personalized Medicine. PMID:26692759
Transferrin-bound proteins as potential biomarkers for advanced breast cancer patients. PMID:26673961
Antiviral innate immunity through the lens of systems biology. PMID:26657882
A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators. PMID:26643252
Detecting Protein Complexes in Protein Interaction Networks Modeled as Gene Expression Biclusters. PMID:26641660
Transcriptional program for nitrogen starvation-induced lipid accumulation in Chlamydomonas reinhardtii. PMID:26633994
PPIM: A Protein-Protein Interaction Database for Maize. PMID:26620522
Multisystem Lewy body disease and the other parkinsonian disorders. PMID:26620112
Comparative Genome and Network Centrality Analysis to Identify Drug Targets of Mycobacterium tuberculosis H37Rv. PMID:26618166
Raf/ERK drives the proliferative and invasive phenotype of BMPR2-silenced pulmonary artery endothelial cells. PMID:26589479
Cellular reprogramming through mitogen-activated protein kinases. PMID:26579181
CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal During Cardiac Remodeling. PMID:26578544
Investigation of Pathogenic Genes in Chinese sporadic Hypertrophic Cardiomyopathy Patients by Whole Exome Sequencing. PMID:26573135
Adaptation to High Ethanol Reveals Complex Evolutionary Pathways. PMID:26545090
Lactobacillus acidophilus-Rutin Interplay Investigated by Proteomics. PMID:26544973
Identifying Novel Candidate Genes Related to Apoptosis from a Protein-Protein Interaction Network. PMID:26543496
SYSTEM-WIDE MAPPING OF ACTIVATED CIRCUITRY IN EXPERIMENTAL SYSTEMIC INFLAMMATORY RESPONSE SYNDROME. PMID:26536201
Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma. PMID:26529251
Bioinformatics Knowledge Map for Analysis of Beta-Catenin Function in Cancer. PMID:26509276
Identifying New Candidate Genes and Chemicals Related to Prostate Cancer Using a Hybrid Network and Shortest Path Approach. PMID:26504486
Tumor-host signaling interaction reveals a systemic, age-dependent splenic immune influence on tumor development. PMID:26497558
A Glimpse to Background and Characteristics of Major Molecular Biological Networks. PMID:26491677
MAS C-Terminal Tail Interacting Proteins Identified by Mass Spectrometry- Based Proteomic Approach. PMID:26484771
Protein Analysis of Sapienic Acid-Treated Porphyromonas gingivalis Suggests Differential Regulation of Multiple Metabolic Pathways. PMID:26483519
Carboxydotrophic growth of Geobacter sulfurreducens. PMID:26481622
Characterization and quantification of proteins secreted by single human embryos prior to implantation. PMID:26471863
AztD, a Periplasmic Zinc Metallochaperone to an ATP-binding Cassette (ABC) Transporter System in Paracoccus denitrificans. PMID:26468286
Virtual pathway explorer (viPEr) and pathway enrichment analysis tool (PEANuT): creating and analyzing focus networks to identify cross-talk between molecules and pathways. PMID:26467653
Reduced keratin expression in colorectal neoplasia and associated fields is reversible by diet and resection. PMID:26462274
Determining Roles of Accessory Genes in Denitrification by Mutant Fitness Analyses. PMID:26452555
The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence. PMID:26416763
KLK1 and ZG16B proteins and arginine-proline metabolism identified as novel targets to monitor atherosclerosis, acute coronary syndrome and recovery. PMID:26413039
Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length. PMID:26365526
RNA helicase DDX3: a novel therapeutic target in Ewing sarcoma. PMID:26364611
Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation. PMID:26320211
Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes. PMID:26311884
Systematic tracking of dysregulated modules identifies disrupted pathways in narcolepsy. PMID:26309600
Identification of Drosophila centromere associated proteins by quantitative affinity purification-mass spectrometry. PMID:26306323
Development of Bioinformatics Pipeline for Analyzing Clinical Pediatric NGS Data. PMID:26306272
Gene Function Prediction from Functional Association Networks Using Kernel Partial Least Squares Regression. PMID:26288239
OVA: integrating molecular and physical phenotype data from multiple biomedical domain ontologies with variant filtering for enhanced variant prioritization. PMID:26272982
Identifying miRNA/mRNA negative regulation pairs in colorectal cancer. PMID:26269151
Human respiratory syncytial virus non-structural protein NS1 modifies miR-24 expression via transforming growth factor-β. PMID:26253191
Protein interaction network constructing based on text mining and reinforcement learning with application to prostate cancer. PMID:26243825
Introducing differential expression of human heat shock protein 27 in hepatocellular carcinoma: moving toward identification of cancer biomarker. PMID:26242269
Molecular mechanisms of the non-coenzyme action of thiamin in brain: biochemical, structural and pathway analysis. PMID:26212886
Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases. PMID:26209609
Prediction of Links and Weights in Networks by Reliable Routes. PMID:26198206
Acquisition of estrogen independence induces TOB1-related mechanisms supporting breast cancer cell proliferation. PMID:26165839
Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis. PMID:26125048
Citrullination of myofilament proteins in heart failure. PMID:26113265
Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes. PMID:26108689
Mam33 promotes cytochrome c oxidase subunit I translation in Saccharomyces cerevisiae mitochondria. PMID:26108620
Reversal of the Transcriptome by Prostaglandin E2 during Myofibroblast Dedifferentiation. PMID:26098591
Proteins interaction network and modeling of IGVH mutational status in chronic lymphocytic leukemia. PMID:26088082
Powerful Tukey's One Degree-of-Freedom Test for Detecting Gene-Gene and Gene-Environment Interactions. PMID:26064040
Maximum flow approach to prioritize potential drug targets of Mycobacterium tuberculosis H37Rv from protein-protein interaction network. PMID:26061871
Identification of New Candidate Genes and Chemicals Related to Esophageal Cancer Using a Hybrid Interaction Network of Chemicals and Proteins. PMID:26058041
ONION: Functional Approach for Integration of Lipidomics and Transcriptomics Data. PMID:26053255
Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk. PMID:26051272
Impact of microfluidic processing on bacterial ribonucleic acid expression. PMID:26045727
Characterization of the proteome of cytoplasmic lipid droplets in mouse enterocytes after a dietary fat challenge. PMID:25992653
Phosphodiesterase sequence variants may predispose to prostate cancer. PMID:25979379
Proteomic profiling of high risk medulloblastoma reveals functional biology. PMID:25970789
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity. PMID:25970248
Rv2031c of Mycobacterium tuberculosis: a master regulator of Rv2028-Rv2031 (HspX) operon. PMID:25964780
Polymorphism at 19q13.41 Predicts Breast Cancer Survival Specifically after Endocrine Therapy. PMID:25964295
Wound healing and longevity: lessons from long-lived αMUPA mice. PMID:25960543
Identification of transcriptional factors and key genes in primary osteoporosis by DNA microarray. PMID:25957414
Novel Host Proteins and Signaling Pathways in Enteropathogenic E. coli Pathogenesis Identified by Global Phosphoproteome Analysis. PMID:25944883
Construction and Analysis of the Cell Surface's Protein Network for Human Sperm-Egg Interaction. PMID:25937952
Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth. PMID:25931508
Targeted inhibition of galectin 1 by thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats. PMID:25920776
MicroRNA Levels as Prognostic Markers for the Differentiation Potential of Human Mesenchymal Stromal Cell Donors. PMID:25915705
Functional Proteomics Identifies Acinus L as a Direct Insulin- and Amino Acid-Dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Substrate. PMID:25907765
DomSign: a top-down annotation pipeline to enlarge enzyme space in the protein universe. PMID:25888481
Neuroblastoma tyrosine kinase signaling networks involve FYN and LYN in endosomes and lipid rafts. PMID:25884760
Identification of novel thyroid cancer-related genes and chemicals using shortest path algorithm. PMID:25874234
Wnt directs the endosomal flux of LDL-derived cholesterol and lipid droplet homeostasis. PMID:25851648
Disease gene prioritization using network and feature. PMID:25844670
Violating the theory of single gene-single disorder: inhibitor development in hemophilia. PMID:25825553
Properties of protein drug target classes. PMID:25822509
Methylation-associated partial down-regulation of mesothelin causes resistance to anti-mesothelin immunotoxins in a pancreatic cancer cell line. PMID:25803818
MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition. PMID:25803170
LC-MS/MS-based serum proteomics for identification of candidate biomarkers for hepatocellular carcinoma. PMID:25778709
A hybrid computational method for the discovery of novel reproduction-related genes. PMID:25768094
Advantages and limitations of shot-gun proteomic analyses on Arabidopsis plants with altered MAPK signaling. PMID:25763005
PathCards: multi-source consolidation of human biological pathways. PMID:25725062
Transcriptome meta-analysis reveals dysregulated pathways in nasopharyngeal carcinoma. PMID:25724187
A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions. PMID:25720483
Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity. PMID:25713356
Quantitative phosphoproteomics analysis reveals a key role of insulin growth factor 1 receptor (IGF1R) tyrosine kinase in human sperm capacitation. PMID:25693802
BolA is a transcriptional switch that turns off motility and turns on biofilm development. PMID:25691594
Unlocking proteomic heterogeneity in complex diseases through visual analytics. PMID:25684269
Dynamic changes in the expression of apoptosis-related genes in differentiating gonocytes and in seminomas. PMID:25677133
An integrated approach for analyzing clinical genomic variant data from next-generation sequencing. PMID:25649353
Exploring bacterial organelle interactomes: a model of the protein-protein interaction network in the Pdu microcompartment. PMID:25646976
Dissecting the molecular properties of prokaryotic flotillins. PMID:25635948
Discovery of new candidate genes related to brain development using protein interaction information. PMID:25635857
Identification of the differentially expressed genes associated with familial combined hyperlipidemia using bioinformatics analysis. PMID:25625967
Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells. PMID:25599176
Histology-directed and imaging mass spectrometry: An emerging technology in ectopic calcification. PMID:25595835
Symptom-driven idiopathic disease gene identification. PMID:25590976
Proceedings of the Thirteenth Annual UT- KBRIN Bioinformatics Summit 2014. PMID:25571995
Differential transcriptome profile of peripheral white cells to identify biomarkers involved in oxaliplatin induced neuropathy. PMID:25563226
Reproducibility enhancement and differential expression of non predefined functional gene sets in human genome. PMID:25539829
INTEGRATING COMPUTATIONAL PROTEIN FUNCTION PREDICTION INTO DRUG DISCOVERY INITIATIVES. PMID:25530654
Schizophrenia and cortical blindness: protective effects and implications for language. PMID:25506321
A chemical proteomics approach for global analysis of lysine monomethylome profiling. PMID:25505155
Chromosomal Instability and Phosphoinositide Pathway Gene Signatures in Glioblastoma Multiforme. PMID:25502460
White adipose tissue reference network: a knowledge resource for exploring health-relevant relations. PMID:25466819
Defining the nociceptor transcriptome. PMID:25426020
RNA-sequencing reveals early, dynamic transcriptome changes in the corollas of pollinated petunias. PMID:25403317
Using biological networks to improve our understanding of infectious diseases. PMID:25379138
Proteomic analysis of human plasma in chronic rheumatic mitral stenosis reveals proteins involved in the complement and coagulation cascade. PMID:25379033
A pan-cancer modular regulatory network analysis to identify common and cancer-specific network components. PMID:25374456
Pathogenesis analysis of pituitary adenoma based on gene expression profiling. PMID:25360166
STRING v10: protein-protein interaction networks, integrated over the tree of life. PMID:25352553
Proteomes of host cell membranes modified by intracellular activities of Salmonella enterica. PMID:25348832
Multiplexed digital mRNA profiling of the inflammatory response in the West Nile Swiss Webster mouse model. PMID:25340818
Proteomic and biochemical analyses show a functional network of proteins involved in antioxidant defense of the Arabidopsis anp2anp3 double mutant. PMID:25325904
Identification of proteins found to be significantly altered when comparing the serum proteome from Multiple Myeloma patients with varying degrees of bone disease. PMID:25322877
Genetic, psychosocial and clinical factors associated with hippocampal volume in the general population. PMID:25313508
Insights into acetate toxicity in Zymomonas mobilis 8b using different substrates. PMID:25298783
Computational biophysical, biochemical, and evolutionary signature of human R-spondin family proteins, the member of canonical Wnt/β-catenin signaling pathway. PMID:25276837
In-depth quantitative proteomic analysis of de novo protein synthesis induced by brain-derived neurotrophic factor. PMID:25271054
ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses. PMID:25269479
A random set scoring model for prioritization of disease candidate genes using protein complexes and data-mining of GeneRIF, OMIM and PubMed records. PMID:25253562
Proteomic study reveals a functional network of cancer markers in the G1-Stage of the breast cancer cell cycle. PMID:25252636
Excretion of urinary orosomucoid 1 protein is elevated in patients with chronic heart failure. PMID:25215505
Interactome analysis of the influenza A virus transcription/replication machinery identifies protein phosphatase 6 as a cellular factor required for efficient virus replication. PMID:25187537
Differential cysteine labeling and global label-free proteomics reveals an altered metabolic state in skeletal muscle aging. PMID:25181601
Prenatal maternal immune activation causes epigenetic differences in adolescent mouse brain. PMID:25180573
Functional and genomic context in pathway analysis of GWAS data. PMID:25154796
Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease. PMID:25153994
Proteomic investigation into betulinic acid-induced apoptosis of human cervical cancer HeLa cells. PMID:25148076
MYC and EGR1 synergize to trigger tumor cell death by controlling NOXA and BIM transcription upon treatment with the proteasome inhibitor bortezomib. PMID:25147211
Mass spectrometry based proteomic analysis of salivary glands of urban malaria vector Anopheles stephensi. PMID:25126571
Identification of Differentially Expressed Gene after Femoral Fracture via Microarray Profiling. PMID:25110652
The Succinated Proteome of FH-Mutant Tumours. PMID:25105836
Prediction and functional analysis of the sweet orange protein-protein interaction network. PMID:25091279
Whole genome DNA methylation signature of HER2-positive breast cancer. PMID:25089541
Proteomic analysis of free-living Bradyrhizobium diazoefficiens: highlighting potential determinants of a successful symbiosis. PMID:25086822
Finding pathway-modulating genes from a novel Ontology Fingerprint-derived gene network. PMID:25063300
Genetic similarities between tobacco use disorder and related comorbidities: an exploratory study. PMID:25060307
A graphic method for identification of novel glioma related genes. PMID:25050377
Accurate in silico identification of species-specific acetylation sites by integrating protein sequence-derived and functional features. PMID:25042424
An empirical study of different approaches for protein classification. PMID:25028675
Large-scale structure of a network of co-occurring MeSH terms: statistical analysis of macroscopic properties. PMID:25006672
Proteogenomic convergence for understanding cancer pathways and networks. PMID:24994965
Temporal gene expression analysis of Sjögren's syndrome in C57BL/6.NOD-Aec1Aec2 mice based on microarray time-series data using an improved empirical Bayes approach. PMID:24990690
Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes. PMID:24987309
Simulated annealing based algorithm for identifying mutated driver pathways in cancer. PMID:24982873
Improving functional annotation for industrial microbes: a case study with Pichia pastoris. PMID:24929579
Involvement of YODA and mitogen activated protein kinase 6 in Arabidopsis post-embryogenic root development through auxin up-regulation and cell division plane orientation. PMID:24923680
Probing phosphorylation-dependent protein interactions within functional domains of histone deacetylase 5 (HDAC5). PMID:24920159
Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy. PMID:24912190
miRror-Suite: decoding coordinated regulation by microRNAs. PMID:24907353
Elucidation of Zymomonas mobilis physiology and stress responses by quantitative proteomics and transcriptomics. PMID:24904559
MIR137 variants identified in psychiatric patients affect synaptogenesis and neuronal transmission gene sets. PMID:24888363
The Index-based Subgraph Matching Algorithm with General Symmetries (ISMAGS): exploiting symmetry for faster subgraph enumeration. PMID:24879305
Systematic family-wide analysis of sodium bicarbonate cotransporter NBCn1/SLC4A7 interactions with PDZ scaffold proteins. PMID:24844638
Fetal alcohol syndrome, chemo-biology and OMICS: ethanol effects on vitamin metabolism during neurodevelopment as measured by systems biology analysis. PMID:24816220
Changes in metabolite profiles caused by genetically determined obesity in mice. PMID:24772056
Impact of NGS in the medical sciences: Genetic syndromes with an increased risk of developing cancer as an example of the use of new technologies. PMID:24764758
Identifying gastric cancer related genes using the shortest path algorithm and protein-protein interaction network. PMID:24729971
Sizing up models of heart failure: Proteomics from flies to humans. PMID:24723306
Proteins recruited to exosomes by tau overexpression implicate novel cellular mechanisms linking tau secretion with Alzheimer's disease. PMID:24718102
The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes. PMID:24710217
Delayed administration of bone marrow mesenchymal stem cell conditioned medium significantly improves outcome after retinal ischemia in rats. PMID:24699381
Effect of Wnt3a on keratinocytes utilizing in vitro and bioinformatics analysis. PMID:24686518
Expression of targeted ribozyme against telomerase RNA causes altered expression of several other genes in tumor cells. PMID:24664581
Noncanonical Gβ Gib2 is a scaffolding protein promoting cAMP signaling through functions of Ras1 and Cac1 proteins in Cryptococcus neoformans. PMID:24659785
Analysis of protein-protein interaction network and functional modules on primary osteoporosis. PMID:24656062
ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration. PMID:24618899
Identification of salivary gland proteins depleted after blood feeding in the malaria vector Anopheles campestris-like mosquitoes (Diptera: Culicidae). PMID:24599352
A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells. PMID:24596151
Differential evolutionary constraints in the evolution of chemoreceptors: a murine and human case study. PMID:24587745
A genome-wide MeSH-based literature mining system predicts implicit gene-to-gene relationships and networks. PMID:24555475
Systems biology-based identification of Mycobacterium tuberculosis persistence genes in mouse lungs. PMID:24549847
Monitoring and Inhibiting MT1-MMP during Cancer Initiation and Progression. PMID:24549119
A temporal examination of the planktonic and biofilm proteome of whole cell Pseudomonas aeruginosa PAO1 using quantitative mass spectrometry. PMID:24532839
The predictability of molecular evolution during functional innovation. PMID:24516157
ISMARA: automated modeling of genomic signals as a democracy of regulatory motifs. PMID:24515121
Subclinical inflammatory status in Rett syndrome. PMID:24511209
H(2)O(2) production in species of the Lactobacillus acidophilus group: a central role for a novel NADH-dependent flavin reductase. PMID:24487531
Identification of age-related macular degeneration related genes by applying shortest path algorithm in protein-protein interaction network. PMID:24455700
An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription. PMID:24434558
Plasma protein profiling of Mild Cognitive Impairment and Alzheimer's disease using iTRAQ quantitative proteomics. PMID:24433274
Integrative radiation systems biology. PMID:24411063
Phosphoproteomics and bioinformatics analyses of spinal cord proteins in rats with morphine tolerance. PMID:24392096
Tyrosine kinase receptors as molecular targets in pheochromocytomas and paragangliomas. PMID:24390213
A de novo convergence of autism genetics and molecular neuroscience. PMID:24387789
Protein complex identification by integrating protein-protein interaction evidence from multiple sources. PMID:24386289
Network analysis of transcription factors for nuclear reprogramming into induced pluripotent stem cell using bioinformatics. PMID:24381858
ParP prevents dissociation of CheA from chemotactic signaling arrays and tethers them to a polar anchor. PMID:24379357
Over-expression of hNGF in adult human olfactory bulb neural stem cells promotes cell growth and oligodendrocytic differentiation. PMID:24367504
Bioinformatics analysis for the antirheumatic effects of huang-lian-jie-du-tang from a network perspective. PMID:24348693
Proteomic analysis of mismatch repair-mediated alkylating agent-induced DNA damage response. PMID:24330662
Differential expression of proteins in brain regions of Alzheimer's disease patients. PMID:24306222
Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype. PMID:24292680
A novel phenotypic dissimilarity method for image-based high-throughput screens. PMID:24256072
Molecular mechanisms of system responses to novel stimuli are predictable from public data. PMID:24185701
Expression of the mevalonate pathway enzymes in the Lutzomyia longipalpis (Diptera: Psychodidae) sex pheromone gland demonstrated by an integrated proteomic approach. PMID:24185139
Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli. PMID:24176774
Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family. PMID:24174223
Identifying genes relevant to specific biological conditions in time course microarray experiments. PMID:24146889
Reconstructing targetable pathways in lung cancer by integrating diverse omics data. PMID:24135919
Comparative analysis of differential network modularity in tissue specific normal and cancer protein interaction networks. PMID:24093757
Tobacco LSU-like protein couples sulphur-deficiency response with ethylene signalling pathway. PMID:24085579
Prediction of effective drug combinations by chemical interaction, protein interaction and target enrichment of KEGG pathways. PMID:24083237
Osteoprotegerin in exosome-like vesicles from human cultured tubular cells and urine. PMID:24058411
The nebulin SH3 domain is dispensable for normal skeletal muscle structure but is required for effective active load bearing in mouse. PMID:24046450
Stable isotope metabolic labeling-based quantitative phosphoproteomic analysis of Arabidopsis mutants reveals ethylene-regulated time-dependent phosphoproteins and putative substrates of constitutive triple response 1 kinase. PMID:24043427
Dissecting virus-plant interactions through proteomics approaches. PMID:24039615
Dynamics of DNA damage induced pathways to cancer. PMID:24023735
Unraveling the Leloir pathway of Bifidobacterium bifidum: significance of the uridylyltransferases. PMID:24014529
Proteomic analysis of seminal fluid from men exhibiting oxidative stress. PMID:24004880
Exploiting human CD34+ stem cell-conditioned medium for tissue repair. PMID:23985698
Comparative proteomics reveals novel components at the plasma membrane of differentiated HepaRG cells and different distribution in hepatocyte- and biliary-like cells. PMID:23977166
Down regulation of T cell receptor expression in COPD pulmonary CD8 cells. PMID:23977094
Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes. PMID:23963736
Expression pattern of serum cytokines in hepatitis B virus infected patients with persistently normal alanine aminotransferase levels. PMID:23954997
Human growth is associated with distinct patterns of gene expression in evolutionarily conserved networks. PMID:23941278
Integrative mechanisms of oriented neuronal migration in the developing brain. PMID:23937349
Candidate serum biomarkers for early intestinal cancer using 15N metabolic labeling and quantitative proteomics in the ApcMin/+ mouse. PMID:23924158
Environmental shaping of codon usage and functional adaptation across microbial communities. PMID:23921637
Kinetic differences in the induction of interferon stimulated genes by interferon-α and interleukin 28B are altered by infection with hepatitis C virus. PMID:23913866
Constitutive activation of signal transducer and activator of transcription 3 (STAT3) and nuclear factor κB signaling in glioblastoma cancer stem cells regulates the Notch pathway. PMID:23902772
Summarizing cellular responses as biological process networks. PMID:23895181
Systems biology analysis of Zymomonas mobilis ZM4 ethanol stress responses. PMID:23874800
Magnetic fractionation and proteomic dissection of cellular organelles occupied by the late replication complexes of Semliki Forest virus. PMID:23864636
Bioinformatics for spermatogenesis: annotation of male reproduction based on proteomics. PMID:23852026
Protein biomarkers distinguish between high- and low-risk pediatric acute lymphoblastic leukemia in a tissue specific manner. PMID:23849470
Interleukin-6 expression under gravitational stress due to vibration and hypergravity in follicular thyroid cancer cells. PMID:23844163
Predicting and analyzing interactions between Mycobacterium tuberculosis and its human host. PMID:23844013
Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. PMID:23824909
Multiscale modeling of the causal functional roles of nsSNPs in a genome-wide association study: application to hypoxia. PMID:23819581
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PMID:23806337
Hypothalamic and amygdalar cell lines differ markedly in mitochondrial rather than nuclear encoded gene expression. PMID:23800343
mirTools 2.0 for non-coding RNA discovery, profiling, and functional annotation based on high-throughput sequencing. PMID:23778453
Complex disease interventions from a network model for type 2 diabetes. PMID:23776558
Neuron enriched nuclear proteome isolated from human brain. PMID:23768213
Identifying chemicals with potential therapy of HIV based on protein-protein and protein-chemical interaction network. PMID:23762317
DigSee: Disease gene search engine with evidence sentences (version cancer). PMID:23761452
Members of the Sinorhizobium meliloti ChvI regulon identified by a DNA binding screen. PMID:23758731
Pre- and early-postnatal nutrition modify gene and protein expressions of muscle energy metabolism markers and phospholipid Fatty Acid composition in a muscle type specific manner in sheep. PMID:23755234
Protective effects of andrographolide analogue AL-1 on ROS-induced RIN-mβ cell death by inducing ROS generation. PMID:23750203
An improved hypergeometric probability method for identification of functionally linked proteins using phylogenetic profiles. PMID:23750082
Construction of protein phosphorylation networks by data mining, text mining and ontology integration: analysis of the spindle checkpoint. PMID:23749465
Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition. PMID:23749060
Tissue inhibitor of metalloproteinases-3 moderates the proinflammatory status of macrophages. PMID:23742180
Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder. PMID:23730306
Protein expression profiling of nuclear membrane protein reveals potential biomarker of human hepatocellular carcinoma. PMID:23724895
A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors. PMID:23703321
Relevant Networks involving the p53 Signalling Pathway in Renal Cell Carcinoma. PMID:23675247
Genetic signatures reveal high-altitude adaptation in a set of ethiopian populations. PMID:23666210
Enrichment map profiling of the cancer invasion front suggests regulation of colorectal cancer progression by the bone morphogenetic protein antagonist, gremlin-1. PMID:23659962
Toxicological effects of the different substances in tobacco smoke on human embryonic development by a systems chemo-biology approach. PMID:23637898
Chapter 15: disease gene prioritization. PMID:23633938
Explaining microbial phenotypes on a genomic scale: GWAS for microbes. PMID:23625995
The index-based subgraph matching algorithm (ISMA): fast subgraph enumeration in large networks using optimized search trees. PMID:23620730
Proteomic Profiling of Ex Vivo Expanded CD34-Positive Haematopoetic Cells Derived from Umbilical Cord Blood. PMID:23606859
Construction and analysis of the protein-protein interaction network related to essential hypertension. PMID:23587307
Signal propagation in protein interaction network during colorectal cancer progression. PMID:23586028
Fine mapping for Weaver syndrome in Brown Swiss cattle and the identification of 41 concordant mutations across NRCAM, PNPLA8 and CTTNBP2. PMID:23527149
Identification and characterization of potential therapeutic candidates in emerging human pathogen Mycobacterium abscessus: a novel hierarchical in silico approach. PMID:23527108
Proteomics analysis of hepatoprotective effects for scoparone using MALDI-TOF/TOF mass spectrometry with bioinformatics. PMID:23514563
Combining heterogeneous data sources for accurate functional annotation of proteins. PMID:23514123
Keratin gene expression profiles after digit amputation in C57BL/6 vs. regenerative MRL mice imply an early regenerative keratinocyte activated-like state. PMID:23512742
Proteomic profiling of bronchoalveolar lavage fluid in critically ill patients with ventilator-associated pneumonia. PMID:23505561
Preferential duplication of intermodular hub genes: an evolutionary signature in eukaryotes genome networks. PMID:23468868
In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion. PMID:23443137
PDGFRB promotes liver metastasis formation of mesenchymal-like colorectal tumor cells. PMID:23441134
Immunohistochemical staining, laser capture microdissection, and filter-aided sample preparation-assisted proteomic analysis of target cell populations within tissue samples. PMID:23436586
Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells. PMID:23393188
Simultaneous reconstruction of multiple signaling pathways via the prize-collecting steiner forest problem. PMID:23383998
Discovery and analysis of consistent active sub-networks in cancers. PMID:23368093
A review of integration strategies to support gene regulatory network construction. PMID:23365519
The Epstein-Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins. PMID:23358825
Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases. PMID:23355459
Distinct protein classes in human red cell proteome revealed by similarity of phylogenetic profiles. PMID:23349899
Detecting recurrent gene mutation in interaction network context using multi-scale graph diffusion. PMID:23343428
JContextExplorer: a tree-based approach to facilitate cross-species genomic context comparison. PMID:23324080
Rare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypes. PMID:23321619
Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpoint. PMID:23320540
Proteomic analysis reveals the deregulation of inflammation-related proteins in acupuncture-treated rats with asthma onset. PMID:23304218
Interaction of proteins identified in human thyroid cells. PMID:23303277
Wrangling phosphoproteomic data to elucidate cancer signaling pathways. PMID:23300999
A pathway-based analysis on the effects of obstructive sleep apnea in modulating visceral fat transcriptome. PMID:23288968
Meta-analytical biomarker search of EST expression data reveals three differentially expressed candidates. PMID:23282184
Managing biological complexity across orthologs with a visual knowledgebase of documented biomolecular interactions. PMID:23264875
Computational prediction of protein-protein interactions in Leishmania predicted proteomes. PMID:23251492
PRC2/EED-EZH2 complex is up-regulated in breast cancer lymph node metastasis compared to primary tumor and correlates with tumor proliferation in situ. PMID:23251464
The Cytotoxicity Mechanism of 6-Shogaol-Treated HeLa Human Cervical Cancer Cells Revealed by Label-Free Shotgun Proteomics and Bioinformatics Analysis. PMID:23243437
Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma. PMID:23242808
Architecture for interoperable software in biology. PMID:23235920
Protein expression in the midgut of sugar-fed Aedes albopictus females. PMID:23232105
RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition. PMID:23213202
Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb. PMID:23211419
STRING v9.1: protein-protein interaction networks, with increased coverage and integration. PMID:23203871
Interactogeneous: disease gene prioritization using heterogeneous networks and full topology scores. PMID:23185389
Proteomic snapshot of breast cancer cell cycle: G1/S transition point. PMID:23152136
Time-dependent network analysis reveals molecular targets underlying the development of diet-induced obesity and non-alcoholic steatohepatitis. PMID:23149694
Proteomics identifies differentially expressed proteins in neonatal murine thymus compared with adults. PMID:23134655
Long non-coding RNAs function annotation: a global prediction method based on bi-colored networks. PMID:23132350
Use of biotinylated ubiquitin for analysis of rat brain mitochondrial proteome and interactome. PMID:23109873
Linkers of cell polarity and cell cycle regulation in the fission yeast protein interaction network. PMID:23093924
Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway. PMID:23079576
Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins. PMID:23071613
Popular computational methods to assess multiprotein complexes derived from label-free affinity purification and mass spectrometry (AP-MS) experiments. PMID:23071097
Network-based inference from complex proteomic mixtures using SNIPE. PMID:23060611
Genome-wide patterns of natural variation reveal strong selective sweeps and ongoing genomic conflict in Drosophila mauritiana. PMID:23051690
The drug cocktail network. PMID:23046711
Insights into the pathogenesis of axial spondyloarthropathy from network and pathway analysis. PMID:23046677
Predicting metabolic pathways of small molecules and enzymes based on interaction information of chemicals and proteins. PMID:23029334
What evidence is there for the homology of protein-protein interactions? PMID:23028270
Annotate-it: a Swiss-knife approach to annotation, analysis and interpretation of single nucleotide variation in human disease. PMID:23013645
Systematic deciphering of cancer genome networks. PMID:23012582
Impairment of O-antigen production confers resistance to grazing in a model amoeba-cyanobacterium predator-prey system. PMID:23012457
Multiscale models of breast cancer progression. PMID:23008097
Induced pluripotency and oncogenic transformation are related processes. PMID:22998387
Biological function through network topology: a survey of the human diseasome. PMID:22962330
HYST: a hybrid set-based test for genome-wide association studies, with application to protein-protein interaction-based association analysis. PMID:22958900
Beta adrenergic overstimulation impaired vascular contractility via actin-cytoskeleton disorganization in rabbit cerebral artery. PMID:22916309
Proteomic characterization of phagosomal membrane microdomains during phagolysosome biogenesis and evolution. PMID:22915823
Flux variability scanning based on enforced objective flux for identifying gene amplification targets. PMID:22909053
Human giant congenital melanocytic nevus exhibits potential proteomic alterations leading to melanotumorigenesis. PMID:22906024
Proteomic analysis of plasma membranes isolated from undifferentiated and differentiated HepaRG cells. PMID:22857383
Prediction and analysis of the protein interactome in Pseudomonas aeruginosa to enable network-based drug target selection. PMID:22848443
A smoking-associated 7-gene signature for lung cancer diagnosis and prognosis. PMID:22825454
Multiple independent analyses reveal only transcription factors as an enriched functional class associated with microRNAs. PMID:22824421
A comparison and evaluation of five biclustering algorithms by quantifying goodness of biclusters for gene expression data. PMID:22824157
Clostridium thermocellum ATCC27405 transcriptomic, metabolomic and proteomic profiles after ethanol stress. PMID:22823947
Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosis. PMID:22808064
Deciphering a global network of functionally associated post-translational modifications. PMID:22806145
Cell type specificity of signaling: view from membrane receptors distribution and their downstream transduction networks. PMID:22802048
In-silico identification of phenotype-biased functional modules. PMID:22759578
Global identification of transcriptional regulators of pluripotency and differentiation in embryonic stem cells. PMID:22730289
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. PMID:22703881
Network-induced classification kernels for gene expression profile analysis. PMID:22697242
MoNetFamily: a web server to infer homologous modules and module-module interaction networks in vertebrates. PMID:22689643
Biomine: predicting links between biological entities using network models of heterogeneous databases. PMID:22672646
DroPNet: a web portal for integrated analysis of Drosophila protein-protein interaction networks. PMID:22641854
SteinerNet: a web server for integrating 'omic' data to discover hidden components of response pathways. PMID:22638579
Integrative miRNA-mRNA profiling of adipose tissue unravels transcriptional circuits induced by sleep fragmentation. PMID:22629440
Phosphosignature predicts dasatinib response in non-small cell lung cancer. PMID:22617229
Computational and informatics strategies for identification of specific protein interaction partners in affinity purification mass spectrometry experiments. PMID:22611043
Different evolutionary modifications as a guide to rewire two-component systems. PMID:22586357
SPICE: discovery of phenotype-determining component interplays. PMID:22583800
Linking proteins to signaling pathways for experiment design and evaluation. PMID:22558382
Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks. PMID:22548703
Quantitative proteomics targeting classes of motif-containing peptides using immunoaffinity-based mass spectrometry. PMID:22543061
Predicting the fission yeast protein interaction network. PMID:22540037
Dynamic interactions between Bombyx mori nucleopolyhedrovirus and its host cells revealed by transcriptome analysis. PMID:22532689
Mass spectrometry-based proteomics: existing capabilities and future directions. PMID:22498958
Functional annotation of hierarchical modularity. PMID:22496762
Single nucleotide polymorphism microarray analysis in cortisol-secreting adrenocortical adenomas identifies new candidate genes and pathways. PMID:22496620
Hepatitis C virus network based classification of hepatocellular cirrhosis and carcinoma. PMID:22493692
Proteomics identification of annexin A2 as a key mediator in the metastasis and proangiogenesis of endometrial cells in human adenomyosis. PMID:22493182
Gene expression profile of adult human olfactory bulb and embryonic neural stem cell suggests distinct signaling pathways and epigenetic control. PMID:22485144
Systems analysis of inflammatory bowel disease based on comprehensive gene information. PMID:22480395
A collaborative environment for developing and validating predictive tools for protein biophysical characteristics. PMID:22476577
SdhE is a conserved protein required for flavinylation of succinate dehydrogenase in bacteria. PMID:22474332
PTRF/cavin-1 and MIF proteins are identified as non-small cell lung cancer biomarkers by label-free proteomics. PMID:22461895
Understanding communication signals during mycobacterial latency through predicted genome-wide protein interactions and boolean modeling. PMID:22448278
A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia. PMID:22431509
Transcriptome and network changes in climbers at extreme altitudes. PMID:22393366
Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. PMID:22373819
Comparative analysis and assessment of M. tuberculosis H37Rv protein-protein interaction datasets. PMID:22369691
Prioritizing disease candidate genes by a gene interconnectedness-based approach. PMID:22369140
Preimplantation development regulatory pathway construction through a text-mining approach. PMID:22369103
Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer. PMID:22366898
Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks. PMID:22364233
REGγ is associated with multiple oncogenic pathways in human cancers. PMID:22361172
HIPPIE: Integrating protein interaction networks with experiment based quality scores. PMID:22348130
ANAP: an integrated knowledge base for Arabidopsis protein interaction network analysis. PMID:22345505
Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression. PMID:22344559
Distinct co-evolution patterns of genes associated to DNA polymerase III DnaE and PolC. PMID:22333191
Translating Mendelian and complex inheritance of Alzheimer's disease genes for predicting unique personal genome variants. PMID:22319180
Human kinome profiling identifies a requirement for AMP-activated protein kinase during human cytomegalovirus infection. PMID:22315427
Inferring Biological Mechanisms by Data-Based Mathematical Modelling: Compartment-Specific Gene Activation during Sporulation in Bacillus subtilis as a Test Case. PMID:22312331
Complex-disease networks of trait-associated single-nucleotide polymorphisms (SNPs) unveiled by information theory. PMID:22278381
Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice. PMID:22253740
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. PMID:22252128
Response of fatty acid synthesis genes to the binding of human salivary amylase by Streptococcus gordonii. PMID:22247133
A comprehensive framework for prioritizing variants in exome sequencing studies of Mendelian diseases. PMID:22241780
Connecting the dots between PubMed abstracts. PMID:22235301
Genotype-phenotype correlation in interstitial 6q deletions: a report of 12 new cases. PMID:22218741
Comparison of strategies to detect epistasis from eQTL data. PMID:22205949
From the regulation of peptidoglycan synthesis to bacterial growth and morphology. PMID:22203377
Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets. PMID:22199227
Generation and Analysis of Large-Scale Data-Driven Mycobacterium tuberculosis Functional Networks for Drug Target Identification. PMID:22190924
SySAP: a system-level predictor of deleterious single amino acid polymorphisms. PMID:22183811
Identification of the major functional proteins of prokaryotic lipid droplets. PMID:22180631
Novel search method for the discovery of functional relationships. PMID:22180409
Transcriptional analysis of a Dehalococcoides-containing microbial consortium reveals prophage activation. PMID:22179237
Antibody colocalization microarray: a scalable technology for multiplex protein analysis in complex samples. PMID:22171321
Prediction of 492 human protein kinase substrate specificities. PMID:22165948
Single cell genome sequencing. PMID:22154471
Efficient algorithms for reconstructing gene content by co-evolution. PMID:22151715
Comparative microbial modules resource: generation and visualization of multi-species biclusters. PMID:22144874
Protein-protein interaction networks suggest different targets have different propensities for triggering drug resistance. PMID:22132058
Semantic annotation of biological concepts interplaying microbial cellular responses. PMID:22122862
The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection. PMID:22110760
dbDEPC 2.0: updated database of differentially expressed proteins in human cancers. PMID:22096234
Intermittent hypoxia activates temporally coordinated transcriptional programs in visceral adipose tissue. PMID:22086141
Efficient α, β-motif finder for identification of phenotype-related functional modules. PMID:22078292
PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries. PMID:22070195
Identification of common and cell type specific LXXLL motif EcR cofactors using a bioinformatics refined candidate RNAi screen in Drosophila melanogaster cell lines. PMID:22050674
Functional Genomics Assistant (FUGA): a toolbox for the analysis of complex biological networks. PMID:22035155
The GA and the GWAS: using genetic algorithms to search for multilocus associations. PMID:22025762
DENSE: efficient and prior knowledge-driven discovery of phenotype-associated protein functional modules. PMID:22024446
Proteomic and biochemical analyses reveal the activation of unfolded protein response, ERK-1/2 and ribosomal protein S6 signaling in experimental autoimmune myocarditis rat model. PMID:22014063
Comparison of three quantitative phosphoproteomic strategies to study receptor tyrosine kinase signaling. PMID:22013880
canSAR: an integrated cancer public translational research and drug discovery resource. PMID:22013161
Phosphoproteomic analysis: an emerging role in deciphering cellular signaling in human embryonic stem cells and their differentiated derivatives. PMID:22009073
Characterization of genetic variation and natural selection at the arylamine N-acetyltransferase genes in global human populations. PMID:21995608
Systems-biology approaches to discover anti-viral effectors of the human innate immune response. PMID:21994773
Comparative analysis of the human hepatic and adipose tissue transcriptomes during LPS-induced inflammation leads to the identification of differential biological pathways and candidate biomarkers. PMID:21978410
The human metabolic reconstruction Recon 1 directs hypotheses of novel human metabolic functions. PMID:21962087
Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3' UTR structures. PMID:21957497
Identification of a novel Mcl-1 protein binding motif. PMID:21953453
Unveiling novel genes upregulated by both rhBMP2 and rhBMP7 during early osteoblastic transdifferentiation of C2C12 cells. PMID:21943021
Visualization and exploration of conserved regulatory modules using ReXSpecies 2. PMID:21942985
Quantification of protein group coherence and pathway assignment using functional association. PMID:21929787
Complete genome sequence of the dog commensal and human pathogen Capnocytophaga canimorsus strain 5. PMID:21914877
Ranking candidate disease genes from gene expression and protein interaction: a Katz-centrality based approach. PMID:21912686
Significant effects of antiretroviral therapy on global gene expression in brain tissues of patients with HIV-1-associated neurocognitive disorders. PMID:21909266
Induced sputum proteome in healthy subjects and asthmatic patients. PMID:21906793
Computational approaches to selecting and optimising targets for structural biology. PMID:21906678
Differential profiling studies of N-linked glycoproteins in glioblastoma cancer stem cells upon treatment with γ-secretase inhibitor. PMID:21898824
MIRTFnet: analysis of miRNA regulated transcription factors. PMID:21857930
Exploring pathway interactions in insulin resistant mouse liver. PMID:21843341
Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns. PMID:21836164
Large-scale de novo prediction of physical protein-protein association. PMID:21836163
Prediction of body fluids where proteins are secreted into based on protein interaction network. PMID:21829572
Comprehensive gene expression analysis of human embryonic stem cells during differentiation into neural cells. PMID:21829537
Cooperative transcription factor associations discovered using regulatory variation. PMID:21828005
Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR. PMID:21818401
Exploiting publicly available biological and biochemical information for the discovery of novel short linear motifs. PMID:21799808
Bio::Homology::InterologWalk--a Perl module to build putative protein-protein interaction networks through interolog mapping. PMID:21767381
Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation. PMID:21765947
Unraveling regulation and new components of human P-bodies through a protein interaction framework and experimental validation. PMID:21750099
A majority of the cancer/testis antigens are intrinsically disordered proteins. PMID:21748782
Systematic approaches towards the development of host-directed antiviral therapeutics. PMID:21747723
Network clustering revealed the systemic alterations of mitochondrial protein expression. PMID:21738461
Co-localization of the oncogenic transcription factor MYCN and the DNA methyl binding protein MeCP2 at genomic sites in neuroblastoma. PMID:21731748
Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth. PMID:21721029
Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells. PMID:21712546
DeBi: Discovering Differentially Expressed Biclusters using a Frequent Itemset Approach. PMID:21699691
Copy number variants and infantile spasms: evidence for abnormalities in ventral forebrain development and pathways of synaptic function. PMID:21694734
Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14. PMID:21693558
Small sets of interacting proteins suggest functional linkage mechanisms via Bayesian analogical reasoning. PMID:21685095
Optimally discriminative subnetwork markers predict response to chemotherapy. PMID:21685072
Discovery of biomarker candidates for coronary artery disease from an APOE-knock out mouse model using iTRAQ-based multiplex quantitative proteomics. PMID:21681990
Research resource: New and diverse substrates for the insulin receptor isoform A revealed by quantitative proteomics after stimulation with IGF-II or insulin. PMID:21680660
Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence. PMID:21672909
Visualization of single mRNAs reveals temporal association of proteins with microRNA-regulated mRNA. PMID:21653551
De novo discovery of mutated driver pathways in cancer. PMID:21653252
A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly. PMID:21642980
Quantitative proteomic and interaction network analysis of cisplatin resistance in HeLa cells. PMID:21637840
Sequencing and comparative genome analysis of two pathogenic Streptococcus gallolyticus subspecies: genome plasticity, adaptation and virulence. PMID:21633709
Going deeper: metagenome of a hadopelagic microbial community. PMID:21629664
Assessing the functional coherence of modules found in multiple-evidence networks from Arabidopsis. PMID:21612636
PINTA: a web server for network-based gene prioritization from expression data. PMID:21602267
Quantitative subcellular proteome and secretome profiling of influenza A virus-infected human primary macrophages. PMID:21589892
Evolutionary plasticity determination by orthologous groups distribution. PMID:21586164
CASCADE_SCAN: mining signal transduction network from high-throughput data based on steepest descent method. PMID:21575263
Database and interaction network of genes involved in oral cancer: Version II. PMID:21572887
Unraveling networks of co-regulated genes on the sole basis of genome sequences. PMID:21572103
Expansion of type II CAAX proteases reveals evolutionary origin of γ-secretase subunit APH-1. PMID:21570408
Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus. PMID:21569391
Signalogs: orthology-based identification of novel signaling pathway components in three metazoans. PMID:21559328
Absence of aquaporin-4 in skeletal muscle alters proteins involved in bioenergetic pathways and calcium handling. PMID:21552523
Identification of missense mutation (I12T) in the BSND gene and bioinformatics analysis. PMID:21541222
A 5-formyltetrahydrofolate cycloligase paralog from all domains of life: comparative genomic and experimental evidence for a cryptic role in thiamin metabolism. PMID:21538139
Prioritizing candidate disease genes by network-based boosting of genome-wide association data. PMID:21536720
Ethanol modulation of gene networks: implications for alcoholism. PMID:21536129
Expression of measles virus nucleoprotein induces apoptosis and modulates diverse functional proteins in cultured mammalian cells. PMID:21533140
Using graph theory to analyze biological networks. PMID:21527005
Scoring protein relationships in functional interaction networks predicted from sequence data. PMID:21526183
Characterization of the genomic structure and function of regions influencing renin and angiogenesis in the SS rat. PMID:21521778
Enterotypes of the human gut microbiome. PMID:21508958
Analysis of coevolving gene families using mutually exclusive orthologous modules. PMID:21498882
Gene ontology function prediction in mollicutes using protein-protein association networks. PMID:21486441
Transcriptional regulation via TF-modifying enzymes: an integrative model-based analysis. PMID:21470963
A systems biology approach for the investigation of the heparin/heparan sulfate interactome. PMID:21454685
Retinyl ester storage particles (retinosomes) from the retinal pigmented epithelium resemble lipid droplets in other tissues. PMID:21454509
Modeling and analysis of retinoic acid induced differentiation of uncommitted precursor cells. PMID:21437295
Genomes of the most dangerous epidemic bacteria have a virulence repertoire characterized by fewer genes but more toxin-antitoxin modules. PMID:21437250
Motif-guided sparse decomposition of gene expression data for regulatory module identification. PMID:21426557
Molecular modelling of urease accessory interaction proteins of Helicobacter Pylori J 99 and predicting an interruption in interaction by Vigna radiata Defensins. PMID:21423886
Assembling a protein-protein interaction map of the SSU processome from existing datasets. PMID:21423703
Predicting protein phenotypes based on protein-protein interaction network. PMID:21423698
RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42. PMID:21407211
Proteomic and electron microscopy survey of large assemblies in macrophage cytoplasm. PMID:21406389
Computational analysis of HIV-1 resistance based on gene expression profiles and the virus-host interaction network. PMID:21394196
MicroRNA expression analysis: clinical advantage of propranolol reveals key microRNAs in myocardial infarction. PMID:21386882
CIN85 modulates the down-regulation of Fc gammaRIIa expression and function by c-Cbl in a PKC-dependent manner in human neutrophils. PMID:21372129
A probabilistic model of nuclear import of proteins. PMID:21372083
Mass spectrometry-based immuno-precipitation proteomics - the user's guide. PMID:21365760
Fungome: Annotating proteins implicated in fungal pathogenesis. PMID:21364798
Landscape mapping of functional proteins in insulin signal transduction and insulin resistance: a network-based protein-protein interaction analysis. PMID:21305025
Using transcription modules to identify expression clusters perturbed in Williams-Beuren syndrome. PMID:21304579
In vitro studies indicate a high resistance potential for the lantibiotic nisin in Staphylococcus aureus and define a genetic basis for nisin resistance. PMID:21300840
The effects of EBV transformation on gene expression levels and methylation profiles. PMID:21289059
Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach. PMID:21285413
Predicting functions of proteins in mouse based on weighted protein-protein interaction network and protein hybrid properties. PMID:21283518
Caries induced cytokine network in the odontoblast layer of human teeth. PMID:21261944
Analysis and prediction of translation rate based on sequence and functional features of the mRNA. PMID:21253596
Activation of nuclear factor-kappa B signalling promotes cellular senescence. PMID:21242976
The Biomolecular Interaction Network Database in PSI-MI 2.5. PMID:21233089
An application of the elastic net for an endophenotype analysis. PMID:21229297
Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners. PMID:21223593
Coxiella burnetii transcriptional analysis reveals serendipity clusters of regulation in intracellular bacteria. PMID:21203564
BiologicalNetworks 2.0--an integrative view of genome biology data. PMID:21190573
Functional comparison of innate immune signaling pathways in primates. PMID:21187902
The annotation and the usage of scientific databases could be improved with public issue tracker software. PMID:21186182
PigS and PigP regulate prodigiosin biosynthesis in Serratia via differential control of divergent operons, which include predicted transporters of sulfur-containing molecules. PMID:21183667
A tissue-specific atlas of mouse protein phosphorylation and expression. PMID:21183079
Regulation of peptidoglycan synthesis by outer-membrane proteins. PMID:21183073
The Protein Information and Property Explorer 2: gaggle-like exploration of biological proteomic data within one webpage. PMID:21182202
Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast. PMID:21177495
Towards a genome-wide transcriptogram: the Saccharomyces cerevisiae case. PMID:21169199
Retro-MoRFs: identifying protein binding sites by normal and reverse alignment and intrinsic disorder prediction. PMID:21152297
Antimicrobial peptides increase tolerance to oxidant stress in Drosophila melanogaster. PMID:21148307
Networked-based characterization of extracellular matrix proteins from adult mouse pulmonary and aortic valves. PMID:21133377
Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels. PMID:21126336
ExprEssence--revealing the essence of differential experimental data in the context of an interaction/regulation net-work. PMID:21118483
Glycoproteomic analysis of glioblastoma stem cell differentiation. PMID:21110520
Integrative analysis of genomic, functional and protein interaction data predicts long-range enhancer-target gene interactions. PMID:21109530
DIMA 3.0: Domain Interaction Map. PMID:21097782
Breast cancer biomarker discovery in the functional genomic age: a systematic review of 42 gene expression signatures. PMID:21082037
A stress-responsive system for mitochondrial protein degradation. PMID:21070972
Reactome: a database of reactions, pathways and biological processes. PMID:21067998
Phospho.ELM: a database of phosphorylation sites--update 2011. PMID:21062810
MicroRNA-integrated and network-embedded gene selection with diffusion distance. PMID:21060785
CPLA 1.0: an integrated database of protein lysine acetylation. PMID:21059677
P2CS: a database of prokaryotic two-component systems. PMID:21051349
In silico prediction of human pathogenicity in the γ-proteobacteria. PMID:21048922
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. PMID:21045058
Relationship between human oral lichen planus and oral squamous cell carcinoma at a genomic level: a datamining study. PMID:20975920
A data set of human endogenous protein ubiquitination sites. PMID:20972266
Transcriptomics and proteomics in the study of H1N1 2009. PMID:20970742
SmashCell: a software framework for the analysis of single-cell amplified genome sequences. PMID:20966005
HitPredict: a database of quality assessed protein-protein interactions in nine species. PMID:20947562
The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation. PMID:20944208
DUFs: families in search of function. PMID:20944204
Involvement of EupR, a response regulator of the NarL/FixJ family, in the control of the uptake of the compatible solutes ectoines by the halophilic bacterium Chromohalobacter salexigens. PMID:20942908
iRefWeb: interactive analysis of consolidated protein interaction data and their supporting evidence. PMID:20940177
Application of computational approaches to study signalling networks of nuclear and Tyrosine kinase receptors. PMID:20937105
Archaeal ubiquitin-like proteins: functional versatility and putative ancestral involvement in tRNA modification revealed by comparative genomic analysis. PMID:20936112
Human protein reference database and human proteinpedia as discovery resources for molecular biotechnology. PMID:20927658
A systematic study of genome context methods: calibration, normalization and combination. PMID:20920312
Multi-species integrative biclustering. PMID:20920250
mRNA expression analysis of cell cycle genes in islets of pregnant mice. PMID:20886204
Finding the "dark matter" in human and yeast protein network prediction and modelling. PMID:20885791
Transcriptome analysis indicates an enhanced activation of adaptive and innate immunity by chlamydia-infected murine epithelial cells treated with interferon γ. PMID:20868270
The Plk1-dependent phosphoproteome of the early mitotic spindle. PMID:20860994
Synthetic lethal screen of an EGFR-centered network to improve targeted therapies. PMID:20858866
TRIP Database: a manually curated database of protein-protein interactions for mammalian TRP channels. PMID:20851834
The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea. PMID:20844578
Candidate gene prioritization by network analysis of differential expression using machine learning approaches. PMID:20840752
The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu. PMID:20836087
Finding the right questions: exploratory pathway analysis to enhance biological discovery in large datasets. PMID:20824171
Proteomic changes resulting from gene copy number variations in cancer cells. PMID:20824076
Inferring cancer subnetwork markers using density-constrained biclustering. PMID:20823331
Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo. PMID:20820852
A model-based strategy to investigate the role of microRNA regulation in cancer signalling networks. PMID:20809366
Apolipoprotein B genetic variants modify the response to fenofibrate: a GOLDN study. PMID:20724655
Quantitative proteomics reveals a "poised quiescence" cellular state after triggering the DNA replication origin activation checkpoint. PMID:20707412
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization. PMID:20697350
Meta-analysis of heat- and chemically upregulated chaperone genes in plant and human cells. PMID:20694844
The mitochondrial proteome and human disease. PMID:20690818
Prediction of deleterious non-synonymous SNPs based on protein interaction network and hybrid properties. PMID:20689580
MLTreeMap--accurate Maximum Likelihood placement of environmental DNA sequences into taxonomic and functional reference phylogenies. PMID:20687950
Open source tool for prediction of genome wide protein-protein interaction network based on ortholog information. PMID:20684769
Prediction of metabolic fluxes by incorporating genomic context and flux-converging pattern analyses. PMID:20679215
Cytoscape Web: an interactive web-based network browser. PMID:20656902
Inferring modules from human protein interactome classes. PMID:20653930
Uncovering packaging features of co-regulated modules based on human protein interaction and transcriptional regulatory networks. PMID:20649980
From complete genome sequence to 'complete' understanding? PMID:20647113
Glycoprotein capture and quantitative phosphoproteomics indicate coordinated regulation of cell migration upon lysophosphatidic acid stimulation. PMID:20639409
Viruses in the faecal microbiota of monozygotic twins and their mothers. PMID:20631792
GTC: A web server for integrating systems biology data with web tools and desktop applications. PMID:20626906
Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry. PMID:20601722
Over-expression and purification strategies for recombinant multi-protein oligomers: a case study of Mycobacterium tuberculosis σ/anti-σ factor protein complexes. PMID:20600947
Extending the chinchilla middle ear epithelial model for mucin gene investigation. PMID:20591507
Protein-protein interactions essentials: key concepts to building and analyzing interactome networks. PMID:20589078
Identifying differentially regulated subnetworks from phosphoproteomic data. PMID:20584295
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function. PMID:20576703
Distinct biological network properties between the targets of natural products and disease genes. PMID:20565092
Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages. PMID:20548782
MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screening. PMID:20548102
Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. PMID:20541999
Predicting genetic modifier loci using functional gene networks. PMID:20538624
Analysis and prediction of the metabolic stability of proteins based on their sequential features, subcellular locations and interaction networks. PMID:20532046
The phosphoproteome of toll-like receptor-activated macrophages. PMID:20531401
Computational tools for the interactive exploration of proteomic and structural data. PMID:20525940
A quick guide to large-scale genomic data mining. PMID:20523745
Transcriptional profiling of Clostridium difficile and Caco-2 cells during infection. PMID:20521945
Struct2Net: a web service to predict protein-protein interactions using a structure-based approach. PMID:20513650
A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells. PMID:20505756
Using GeneReg to construct time delay gene regulatory networks. PMID:20500822
Dynamic cross-talk analysis among TNF-R, TLR-4 and IL-1R signalings in TNFalpha-induced inflammatory responses. PMID:20497537
Construction of a large scale integrated map of macrophage pathogen recognition and effector systems. PMID:20470404
Profiling of protein interaction networks of protein complexes using affinity purification and quantitative mass spectrometry. PMID:20445003
Histone chaperones, histone acetylation, and the fluidity of the chromogenome. PMID:20432449
Improved microarray-based decision support with graph encoded interactome data. PMID:20419106
High accuracy operon prediction method based on STRING database scores. PMID:20385580
A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila. PMID:20368357
From evidence to inference: probing the evolution of protein interaction networks. PMID:20357887
Building and analyzing protein interactome networks by cross-species comparisons. PMID:20353594
DONGLE and DEFECTIVE IN ANTHER DEHISCENCE1 lipases are not essential for wound- and pathogen-induced jasmonate biosynthesis: redundant lipases contribute to jasmonate formation. PMID:20348210
Construction and analysis of protein-protein interaction networks. PMID:20334628
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli. PMID:20308541
Glutathione peroxidase 1 protects mitochondria against hypoxia/reoxygenation damage in mouse hearts. PMID:20306076
Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time. PMID:20303064
Time-series gene expression profiles in AGS cells stimulated with Helicobacter pylori. PMID:20238406
SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale. PMID:20214776
[Attenuation regulation of amino acid and amino acyl-tRNA biosynthetic operons in bacteria: comparative genomics analysis]. PMID:20198868
How to understand the cell by breaking it: network analysis of gene perturbation screens. PMID:20195495
SPICi: a fast clustering algorithm for large biological networks. PMID:20185405
Genomicus: a database and a browser to study gene synteny in modern and ancestral genomes. PMID:20185404
Advances in genome studies: The PAG 2010 conference. PMID:20182762
Automated microscopy for high-content RNAi screening. PMID:20176920
Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk. PMID:20167577
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways. PMID:20122211
LAITOR--Literature Assistant for Identification of Terms co-Occurrences and Relationships. PMID:20122157
Biana: a software framework for compiling biological interactions and analyzing networks. PMID:20105306
Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. PMID:20097925
Nuclear proteome analysis of monkey embryonic stem cells during differentiation. PMID:20091144
An integrated phosphoproteomics work flow reveals extensive network regulation in early lysophosphatidic acid signaling. PMID:20071362
Systemic factors dominate mammal protein evolution. PMID:20053642
Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach. PMID:20052266
The C-terminal repeat domain of Spt5 plays an important role in suppression of Rad26-independent transcription coupled repair. PMID:20042611
Fragile histidine triad protein: structure, function, and its association with tumorogenesis. PMID:20033706
Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. PMID:20020773
Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening. PMID:20020055
Network-based Identification of novel cancer genes. PMID:19959820
Reconstructing ancestral gene content by coevolution. PMID:19948819
Phylogeny-guided interaction mapping in seven eukaryotes. PMID:19948065
Role for protein-protein interaction databases in human genetics. PMID:19929610
ELM: the status of the 2010 eukaryotic linear motif resource. PMID:19920119
BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. PMID:19919682
The ATP-binding cassette transporter Cbc (choline/betaine/carnitine) recruits multiple substrate-binding proteins with strong specificity for distinct quaternary ammonium compounds. PMID:19919675
Co-expression networks: graph properties and topological comparisons. PMID:19910304
MBGD update 2010: toward a comprehensive resource for exploring microbial genome diversity. PMID:19906735
Network of Cancer Genes: a web resource to analyze duplicability, orthology and network properties of cancer genes. PMID:19906700
YybT is a signaling protein that contains a cyclic dinucleotide phosphodiesterase domain and a GGDEF domain with ATPase activity. PMID:19901023
eggNOG v2.0: extending the evolutionary genealogy of genes with enhanced non-supervised orthologous groups, species and functional annotations. PMID:19900971
STITCH 2: an interaction network database for small molecules and proteins. PMID:19897548
PepX: a structural database of non-redundant protein-peptide complexes. PMID:19880386
pISTil: a pipeline for yeast two-hybrid Interaction Sequence Tags identification and analysis. PMID:19874608
Evolution of biomolecular networks: lessons from metabolic and protein interactions. PMID:19851337
Accounting for redundancy when integrating gene interaction databases. PMID:19847299
The Universal Protein Resource (UniProt) in 2010. PMID:19843607
Comprehensive classification of nucleotidyltransferase fold proteins: identification of novel families and their representatives in human. PMID:19833706
STARNET 2: a web-based tool for accelerating discovery of gene regulatory networks using microarray co-expression data. PMID:19828039
Glutaredoxins: roles in iron homeostasis. PMID:19811920
Network strategies to understand the aging process and help age-related drug design. PMID:19804610
Achievements and new knowledge unraveled by metagenomic approaches. PMID:19760178
Saint: a lightweight integration environment for model annotation. PMID:19734151
Ontological Discovery Environment: a system for integrating gene-phenotype associations. PMID:19733230
A Novel extracytoplasmic function (ECF) sigma factor regulates virulence in Pseudomonas aeruginosa. PMID:19730690
Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins. PMID:19729411
Extending the models for iron and sulfur oxidation in the extreme acidophile Acidithiobacillus ferrooxidans. PMID:19703284
Cytokine array comparisons of plasma from cycling fertile women on cycle day 5 and ovulation. PMID:19694641
Linking genes to diseases: it's all in the data. PMID:19678910
A comparative genomics, network-based approach to understanding virulence in Vibrio cholerae. PMID:19666715
Scaffolds: interaction platforms for cellular signalling circuits. PMID:19651513
Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo. PMID:19650917
Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome. PMID:19629158
BowTieBuilder: modeling signal transduction pathways. PMID:19566957
A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability. PMID:19536205
Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. PMID:19531213
Evolution and diversity of glutaredoxins in photosynthetic organisms. PMID:19506802
DASMIweb: online integration, analysis and assessment of distributed protein interaction data. PMID:19502495
Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. PMID:19471023
Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease. PMID:19463981
DASMI: exchanging, annotating and assessing molecular interaction data. PMID:19420069
Protein-protein interaction databases: keeping up with growing interactomes. PMID:19403463
Protein databases on the internet. PMID:18265344 -
SVD-phy: improved prediction of protein functional associations through singular value decomposition of phylogenetic profiles
PubMed citations: 45.
45 articles citing: SVD-phy: improved prediction of protein functional associations through singular value decomposition of phylogenetic profiles
Putative Biomarkers in Tears for Diabetic Retinopathy Diagnosis. PMID:35692536
Glycation modulates glutamatergic signaling and exacerbates Parkinson's disease-like phenotypes. PMID:35468899
Screening of potential genes and transcription factors involved in post-radiation cognitive dysfunction in mice via bioinformatics. PMID:35117246
Analysis of Microarray Data from Medulloblastoma Tissue Samples. PMID:34978688
Increased levels of TAR DNA-binding protein 43 in the hippocampus of subjects with bipolar disorder: a postmortem study. PMID:34966974
Network based analysis identifies TP53m-BRCA1/2wt-homologous recombination proficient (HRP) population with enhanced susceptibility to Vigil immunotherapy. PMID:34785763
Co-evolution based machine-learning for predicting functional interactions between human genes. PMID:34753957
GFICLEE: ultrafast tree-based phylogenetic profile method inferring gene function at the genomic-wide level. PMID:34715785
Targeting the VCP-binding motif of ataxin-3 improves phenotypes in Drosophila models of Spinocerebellar Ataxia Type 3. PMID:34563642
The Brachypodium distachyon cold-acclimated plasma membrane proteome is primed for stress resistance. PMID:34544140
Bioinformatics analysis of the role of CXC ligands in the microenvironment of head and neck tumor. PMID:34247149
CladeOScope: functional interactions through the prism of clade-wise co-evolution. PMID:33928243
Integrated analysis of RNA-binding proteins in thyroid cancer. PMID:33711033
A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models. PMID:33705438
The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets. PMID:33237311
Machine learning methods accurately predict host specificity of coronaviruses based on spike sequences alone. PMID:32981683
Scalable phylogenetic profiling using MinHash uncovers likely eukaryotic sexual reproduction genes. PMID:32697802
Over-expression of TOP2A as a prognostic biomarker in patients with glioma. PMID:31938217
LncRNA ZFAS1 serves as a prognostic biomarker to predict the survival of patients with ovarian cancer. PMID:31798702
Identification of potential sialic acid binding proteins on cell membranes by proximity chemical labeling. PMID:31360427
High Functioning Autism with Missense Mutations in Synaptotagmin-Like Protein 4 (SYTL4) and Transmembrane Protein 187 (TMEM187) Genes: SYTL4- Protein Modeling, Protein-Protein Interaction, Expression Profiling and MicroRNA Studies. PMID:31323913
Long non-coding RNA SNHG6 is upregulated in prostate cancer and predicts poor prognosis. PMID:30911973
Magic roundabout is an endothelial-specific ohnolog of ROBO1 which neo-functionalized to an essential new role in angiogenesis. PMID:30802244
Genetic and genomic analyses of testicular hypoplasia in Nellore cattle. PMID:30677076
ACCBN: ant-Colony-clustering-based bipartite network method for predicting long non-coding RNA-protein interactions. PMID:30626319
Identifying a Novel Biomarker TOP2A of Clear Cell Renal Cell Carcinoma (ccRCC) Associated with Smoking by Co-Expression Network Analysis. PMID:30410595
Substrate Specificity Analysis of Dihydrofolate/Dihydromethanopterin Reductase Homologs in Methylotrophic α-Proteobacteria. PMID:30364315
Co-expression network analysis identified CDH11 in association with progression and prognosis in gastric cancer. PMID:30323620
Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice. PMID:30241514
Identification of key genes and pathways using bioinformatics analysis in septic shock children. PMID:30147344
Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP. PMID:30087168
Effect of Productive Human Papillomavirus 16 Infection on Global Gene Expression in Cervical Epithelium. PMID:30045992
GRMDA: Graph Regression for MiRNA-Disease Association Prediction. PMID:29515453
Screening of Potential Genes and Transcription Factors of Postoperative Cognitive Dysfunction via Bioinformatics Methods. PMID:29374768
Identification of membrane-associated proteins with pathogenic potential expressed by Corynebacterium pseudotuberculosis grown in animal serum. PMID:29368627
Co-expression network analysis identified FCER1G in association with progression and prognosis in human clear cell renal cell carcinoma. PMID:29209141
A novel correlation between ATP5A1 gene expression and progression of human clear cell renal cell carcinoma identified by co‑expression analysis. PMID:29207195
ProphTools: general prioritization tools for heterogeneous biological networks. PMID:29186475
Liver segmentation from CT images using a sparse priori statistical shape model (SP-SSM). PMID:28981530
PrePhyloPro: phylogenetic profile-based prediction of whole proteome linkages. PMID:28875072
Link prediction based on non-negative matrix factorization. PMID:28854195
Overexpression of Topoisomerase 2-Alpha Confers a Poor Prognosis in Pancreatic Adenocarcinoma Identified by Co-Expression Analysis. PMID:28815403
An index-based algorithm for fast on-line query processing of latent semantic analysis. PMID:28520747
Correlated duplications and losses in the evolution of palmitoylation writer and eraser families. PMID:28320309
The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible. PMID:27924014 - https://doi.org/10.1093/nar/gkaa1074
- http://dx.doi.org/10.1093/nar/gku1003
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computational predictions
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functional association
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
protein
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metasource: re3data.org
version: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
protein interaction
metasource: Fairsharing.org
version: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metabolic and signaling pathways
metasource: Nucleic Acid Research database catalogue
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protein-protein interactions
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enzyme
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proteomics
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protein interactions
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computational predictions
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
functional association
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
protein
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
protein interaction
metasource: Fairsharing.orgversion: FAIRsharing.org: STRING; STRING; DOI: https://doi.org/10.25504/FAIRsharing.9b7wvk; Last edited: March 19, 2021, 11:35 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metabolic and signaling pathways
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
protein-protein interactions
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enzyme
metasource: re3data.orgversion: re3data.org: STRING; editing status 2019-01-17; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R3VS40 last accessed: 2022-11-04
proteomics
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:31:43.096336
protein interactions
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:31:43.096336
computational predictions functional association protein protein interaction metabolic and signaling pathways protein-protein interactions enzyme proteomics protein interaction
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