GIpred: a computational tool for prediction of GIGANTEA proteins using machine learning algorithm.
PMID:35221569
Circadian Synchrony: Sleep, Nutrition, and Physical Activity.
PMID:35156088
NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1.
PMID:34807912
An hourglass mechanism controls torpor bout length in hibernating garden dormice.
PMID:34762135
Cut the noise or couple up: Coordinating circadian and synthetic clocks.
PMID:34568785
Structure-based design and classifications of small molecules regulating the circadian rhythm period.
PMID:34531414
Circadian regulation of cardiac metabolism.
PMID:34338224
Intercellular coupling between peripheral circadian oscillators by TGF-β signaling.
PMID:34301601
Clock-Modulating Activities of the Anti-Arrhythmic Drug Moricizine.
PMID:34206497
Attenuated SIRT1 Activity Leads to PER2 Cytoplasmic Localization and Dampens the Amplitude of Bmal1 Promoter-Driven Circadian Oscillation.
PMID:34108855
Natural antisense transcript of Period2, Per2AS, regulates the amplitude of the mouse circadian clock.
PMID:34016691
Identification of PCBP1 as a Novel Modulator of Mammalian Circadian Clock.
PMID:33841513
Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs.
PMID:33828235
Sirtuins-Mediated System-Level Regulation of Mammalian Tissues at the Interface between Metabolism and Cell Cycle: A Systematic Review.
PMID:33806509
A Global Search for novel Transcription Factors impacting the Neurospora crassa Circadian Clock.
PMID:33792687
Temporal Dynamic Methods for Bulk RNA-Seq Time Series Data.
PMID:33673721
Clock at the Core of Cancer Development.
PMID:33672910
Cellular Senescence Triggers Altered Circadian Clocks With a Prolonged Period and Delayed Phases.
PMID:33568972
High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains.
PMID:33510298
A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms.
PMID:33443164
Cisplatin's dual-effect on the circadian clock triggers proliferation and apoptosis.
PMID:33364523
Genome-wide correlation analysis to identify amplitude regulators of circadian transcriptome output.
PMID:33318596
Serum factor(s) from lung adenocarcinoma patients regulates the molecular clock expression.
PMID:33221997
Peroxisome Proliferator-Activated Receptors as Molecular Links between Caloric Restriction and Circadian Rhythm.
PMID:33198317
Phosphatase of Regenerating Liver-1 Selectively Times Circadian Behavior in Darkness via Function in PDF Neurons and Dephosphorylation of TIMELESS.
PMID:33157022
Heritable gene expression variability and stochasticity govern clonal heterogeneity in circadian period.
PMID:32745129
Tracking leukemic T-cell transcriptional dynamics in vivo with a blood-based reporter assay.
PMID:32710494
Vulnerability to helpless behavior is regulated by the circadian clock component CRYPTOCHROME in the mouse nucleus accumbens.
PMID:32487727
Post-translational Modifications are Required for Circadian Clock Regulation in Vertebrates.
PMID:32476990
Chemical modulation of circadian rhythms and assessment of cellular behavior via indirubin and derivatives.
PMID:32475398
A Systems Biology Approach Identifies Hidden Regulatory Connections Between the Circadian and Cell-Cycle Checkpoints.
PMID:32372973
Isoform-selective regulation of mammalian cryptochromes.
PMID:32231341
Systems Level Understanding of Circadian Integration with Cell Physiology.
PMID:32061938
Orchestration of Circadian Timing by Macromolecular Protein Assemblies.
PMID:31945377
12-h clock regulation of genetic information flow by XBP1s.
PMID:31935211
Phenotypic proteomic profiling identifies a landscape of targets for circadian clock-modulating compounds.
PMID:31792063
RNA Splicing Factor Mutations That Cause Retinitis Pigmentosa Result in Circadian Dysregulation.
PMID:31726916
The E3 Ligases Spsb1 and Spsb4 Regulate RevErbα Degradation and Circadian Period.
PMID:31607207
At the Interface of Lifestyle, Behavior, and Circadian Rhythms: Metabolic Implications.
PMID:31555652
The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4.
PMID:31522764
Comparative metabolomics of MCF-7 breast cancer cells using different extraction solvents assessed by mass spectroscopy.
PMID:31511569
Identification of pathways that regulate circadian rhythms using a larval zebrafish small molecule screen.
PMID:31455847
The NRON complex controls circadian clock function through regulated PER and CRY nuclear translocation.
PMID:31417156
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice.
PMID:31388006
Effects of BMAL1 Manipulation on the Brain's Master Circadian Clock and Behavior.
PMID:31249486
The importance of determining circadian parameters in pharmacological studies.
PMID:31099023
A Robust Model for Circadian Redox Oscillations.
PMID:31086108
G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment.
PMID:31039152
Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time.
PMID:31030999
Preservation of circadian rhythms by the protein folding chaperone, BiP.
PMID:30888851
GPR158 in the Visual System: Homeostatic Role in Regulation of Intraocular Pressure.
PMID:30855200
Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.
PMID:30746467
Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.
PMID:30696823
Streamlined procedure for gene knockouts using all-in-one adenoviral CRISPR-Cas9.
PMID:30670765
Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.
PMID:30530698
Spliceosome factors target timeless (tim) mRNA to control clock protein accumulation and circadian behavior in Drosophila.
PMID:30516472
Requirement for NF-κB in maintenance of molecular and behavioral circadian rhythms in mice.
PMID:30366905
Computational and experimental insights into the circadian effects of SIRT1.
PMID:30348778
mTOR Signaling, Translational Control, and the Circadian Clock.
PMID:30250482
Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability.
PMID:30120083
Role of Cryptochrome-1 and Cryptochrome-2 in Aldosterone-Producing Adenomas and Adrenocortical Cells.
PMID:29874863
Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.
PMID:29861175
Clocking In Time to Gate Memory Processes: The Circadian Clock Is Part of the Ins and Outs of Memory.
PMID:29849561
mTOR signaling regulates central and peripheral circadian clock function.
PMID:29750810
Identification of circadian clock modulators from existing drugs.
PMID:29666146
The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization.
PMID:29377895
Transcriptomic changes following valproic acid treatment promote neurogenesis and minimize secondary brain injury.
PMID:29251707
The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.
PMID:29216180
Ticking time bombs: connections between circadian clocks and cancer.
PMID:29152229
Stability of Wake-Sleep Cycles Requires Robust Degradation of the PERIOD Protein.
PMID:29103939
Genetic Association of the PERIOD3 (Per3) Clock Gene with Bipolar Disorder.
PMID:29042894
Design Principles of Phosphorylation-Dependent Timekeeping in Eukaryotic Circadian Clocks.
PMID:29038116
In Vitro Bioluminescence Assay to Characterize Circadian Rhythm in Mammary Epithelial Cells.
PMID:28994762
The genomic landscape of human cellular circadian variation points to a novel role for the signalosome.
PMID:28869038
Circadian Clock Model Supports Molecular Link Between PER3 and Human Anxiety.
PMID:28860482
Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7.
PMID:28779160
PRL2 links magnesium flux and sex-dependent circadian metabolic rhythms.
PMID:28679948
A systems theoretic approach to analysis and control of mammalian circadian dynamics.
PMID:28496287
Cell-intrinsic, Bmal1-dependent Circadian Regulation of Temozolomide Sensitivity in Glioblastoma.
PMID:28470120
Akt1 Controls the Timing and Amplitude of Vascular Circadian Gene Expression.
PMID:28452287
Genetic background-dependent effects of murine micro RNAs on circadian clock function.
PMID:28448626
Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder.
PMID:28388406
Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.
PMID:28380384
Systems Chronotherapeutics.
PMID:28351863
PubChem BioAssay: A Decade's Development toward Open High-Throughput Screening Data Sharing.
PMID:28346087
Correspondence: Reply to 'Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα'.
PMID:28332490
[Research advances in circadian rhythm of epileptic seizures].
PMID:28100336
Daily rhythmicity of clock gene transcript levels in fast and slow muscle fibers from Chinese perch (Siniperca chuatsi).
PMID:27931190
The Local Edge Machine: inference of dynamic models of gene regulation.
PMID:27760556
Phosphorylation Regulating the Ratio of Intracellular CRY1 Protein Determines the Circadian Period.
PMID:27721804
Parallel reverse genetic screening in mutant human cells using transcriptomics.
PMID:27482057
Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation.
PMID:27238018
Mood, stress and longevity: convergence on ANK3.
PMID:27217151
Ageing in relation to skeletal muscle dysfunction: redox homoeostasis to regulation of gene expression.
PMID:27215643
Endotoxin Disrupts Circadian Rhythms in Macrophages via Reactive Oxygen Species.
PMID:27168152
Daily magnesium fluxes regulate cellular timekeeping and energy balance.
PMID:27074515
Towards understanding and predicting suicidality in women: biomarkers and clinical risk assessment.
PMID:27046645
Mechanists Must be Holists Too! Perspectives from Circadian Biology.
PMID:26966017
Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank.
PMID:26955885
Lack of association between cluster headache and PER3 clock gene polymorphism.
PMID:26922944
The transcriptomic basis of tissue- and nutrition-dependent sexual dimorphism in the beetle Onthophagus taurus.
PMID:26904187
USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level.
PMID:26756164
Pituitary tumor transforming gene PTTG2 induces psoriasis by regulating vimentin and E-cadherin expression.
PMID:26617803
Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading.
PMID:26611104
Quantifying Stochastic Noise in Cultured Circadian Reporter Cells.
PMID:26588000
BioGPS: building your own mash-up of gene annotations and expression profiles.
PMID:26578587
Defining the robust behaviour of the plant clock gene circuit with absolute RNA timeseries and open infrastructure.
PMID:26468131
Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact.
PMID:26446213
Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock.
PMID:26392558
Circadian Rhythms and Mood Disorders: Are the Phenomena and Mechanisms Causally Related?
PMID:26379559
Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback.
PMID:26323038
KPNB1 mediates PER/CRY nuclear translocation and circadian clock function.
PMID:26319354
Circadian systems biology: When time matters.
PMID:26288701
The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis.
PMID:26232227
Commentary: Targeting LDH enzymes with a stiripentol analog to treat epilepsy.
PMID:26217188
Circadian redox oscillations and metabolism.
PMID:26113283
The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation.
PMID:25981667
Assembly of a comprehensive regulatory network for the mammalian circadian clock: a bioinformatics approach.
PMID:25945798
Cancer/Testis Antigen PASD1 Silences the Circadian Clock.
PMID:25936801
Circadian metabolism in the light of evolution.
PMID:25927923
Manipulating the circadian and sleep cycles to protect against metabolic disease.
PMID:25852644
Circadian regulation of cellular physiology.
PMID:25707277
Genetics and epigenetics of circadian rhythms and their potential roles in neuropsychiatric disorders.
PMID:25652815
Circadian clock proteins in mood regulation.
PMID:25610405
Association of the circadian factor Period 2 to p53 influences p53's function in DNA-damage signaling.
PMID:25411341
Circadian polymorphisms in night owls, in bipolars, and in non-24-hour sleep cycles.
PMID:25395965
Prevalence of cycling genes and drug targets calls for prospective chronotherapeutics.
PMID:25368193
Genetic adaptation of the human circadian clock to day-length latitudinal variations and relevance for affective disorders.
PMID:25358694
Role for LSM genes in the regulation of circadian rhythms.
PMID:25288739
An intensity ratio of interlocking loops determines circadian period length.
PMID:25122753
The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells.
PMID:25103245
Liver clock protein BMAL1 promotes de novo lipogenesis through insulin-mTORC2-AKT signaling.
PMID:25063808
Robust synchronization of coupled circadian and cell cycle oscillators in single mammalian cells.
PMID:25028488
Ras-mediated deregulation of the circadian clock in cancer.
PMID:24875049
Strengths and limitations of period estimation methods for circadian data.
PMID:24809473
Machine learning helps identify CHRONO as a circadian clock component.
PMID:24737000
SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel.
PMID:24725410
Cell type-specific functions of period genes revealed by novel adipocyte and hepatocyte circadian clock models.
PMID:24699442
Testing the role of circadian genes in conferring risk for psychiatric disorders.
PMID:24687905
Synergistic induction of the clock protein PERIOD by insulin-like peptide and prothoracicotropic hormone in Rhodnius prolixus (Hemiptera): implications for convergence of hormone signaling pathways.
PMID:24600396
Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length.
PMID:24158435
Functional analysis of the rodent CK1tau mutation in the circadian clock of a marine unicellular alga.
PMID:24127907
miRNAs are required for generating a time delay critical for the circadian oscillator.
PMID:24094851
Circadian redox and metabolic oscillations in mammalian systems.
PMID:24063592
The Ccr4-not protein complex regulates the phase of the Neurospora circadian clock by controlling white collar protein stability and activity.
PMID:24030828
The CRTC1-SIK1 pathway regulates entrainment of the circadian clock.
PMID:23993098
Photoreceptor phagocytosis is mediated by phosphoinositide signaling.
PMID:23913857
Estimating confidence intervals in predicted responses for oscillatory biological models.
PMID:23895261
Critical differences between isoforms of securin reveal mechanisms of separase regulation.
PMID:23798554
Cracking the O-GlcNAc code in metabolism.
PMID:23647930
Picrotoxin dramatically speeds the mammalian circadian clock independent of Cys-loop receptors.
PMID:23576702
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.
PMID:23555304
FMR1, circadian genes and depression: suggestive associations or false discovery?
PMID:23521777
Chronobiology of Melatonin beyond the Feedback to the Suprachiasmatic Nucleus-Consequences to Melatonin Dysfunction.
PMID:23481642
Global approaches for telling time: omics and the Arabidopsis circadian clock.
PMID:23435351
Histone methyltransferase MLL3 contributes to genome-scale circadian transcription.
PMID:23297224
Molecular mechanism of circadian rhythmicity of seizures in temporal lobe epilepsy.
PMID:23189039
Small molecule modifiers of circadian clocks.
PMID:23161063
The interplay of cis-regulatory elements rules circadian rhythms in mouse liver.
PMID:23144788
Gene and genome parameters of mammalian liver circadian genes (LCGs).
PMID:23071677
Traumatic brain injury-induced dysregulation of the circadian clock.
PMID:23056261
Monitoring cell-autonomous circadian clock rhythms of gene expression using luciferase bioluminescence reporters.
PMID:23052244
The role of circadian clocks in metabolic disease.
PMID:23012586
Transcriptional architecture and chromatin landscape of the core circadian clock in mammals.
PMID:22936566
NAT1/DAP5/p97 and atypical translational control in the Drosophila Circadian Oscillator.
PMID:22904033
Identification of small molecule activators of cryptochrome.
PMID:22798407
Speed control: cogs and gears that drive the circadian clock.
PMID:22748426
Live-cell monitoring of periodic gene expression in synchronous human cells identifies Forkhead genes involved in cell cycle control.
PMID:22740631
USP2a protein deubiquitinates and stabilizes the circadian protein CRY1 in response to inflammatory signals.
PMID:22669941
Smith-Magenis syndrome results in disruption of CLOCK gene transcription and reveals an integral role for RAI1 in the maintenance of circadian rhythmicity.
PMID:22578325
A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response.
PMID:22384149
Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.
PMID:22384121
Circadian disruption and remedial interventions: effects and interventions for jet lag for athletic peak performance.
PMID:22299812
Involvement of stress kinase mitogen-activated protein kinase kinase 7 in regulation of mammalian circadian clock.
PMID:22267733
Tuning the mammalian circadian clock: robust synergy of two loops.
PMID:22194677
Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening.
PMID:22184224
Expression of circadian clock gene human Period2 (hPer2) in human colorectal carcinoma.
PMID:22166120
In vitro circadian rhythms: imaging and electrophysiology.
PMID:21819387
A new mutation affecting FRQ-less rhythms in the circadian system of Neurospora crassa.
PMID:21731506
Circadian regulation of ATP release in astrocytes.
PMID:21653839
Oscillators entrained by food and the emergence of anticipatory timing behaviors.
PMID:21544255
Proteasome function is required for biological timing throughout the twenty-four hour cycle.
PMID:21530263
A systems biological view of intracellular pathogens.
PMID:21349090
Circadian clocks in human red blood cells.
PMID:21270888
High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.
PMID:21179498
Vigilance and validation: Keys to success in RNAi screening.
PMID:21142076
Circadian integration of metabolism and energetics.
PMID:21127246
IKKα contributes to canonical NF-κB activation downstream of Nod1-mediated peptidoglycan recognition.
PMID:20976174
Clocks not winding down: unravelling circadian networks.
PMID:20966970
Multiscale complexity in the mammalian circadian clock.
PMID:20934868
Commentary: the year in circadian rhythms.
PMID:20926591
Genomics and systems approaches in the mammalian circadian clock.
PMID:20926286
JTK_CYCLE: an efficient nonparametric algorithm for detecting rhythmic components in genome-scale data sets.
PMID:20876817
PPARs in Rhythmic Metabolic Regulation and Implications in Health and Disease.
PMID:20871864
Circadian control of global gene expression patterns.
PMID:20809800
Spotlight on post-transcriptional control in the circadian system.
PMID:20803230
Rapid assessment of gene function in the circadian clock using artificial microRNA in Arabidopsis mesophyll protoplasts.
PMID:20709829
Factors affecting reproducibility between genome-scale siRNA-based screens.
PMID:20625183
AKT and TOR signaling set the pace of the circadian pacemaker.
PMID:20619819
Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action.
PMID:20542067
E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha.
PMID:20534529
Circadian rhythms and cancer.
PMID:20237421
Circadian clock control of the cellular response to DNA damage.
PMID:20227409
CRY2 is associated with depression.
PMID:20195522
Development of the circadian oscillator during differentiation of mouse embryonic stem cells in vitro.
PMID:20133594
An overview of the PubChem BioAssay resource.
PMID:19933261
Profile of Steve Kay.
PMID:19846773
High-throughput screening and chemical biology: new approaches for understanding circadian clock mechanisms.
PMID:19778719