KinMutBase
KinMutBase is a comprehensive database of disease-causing mutations in protein kinase domains. This resources provides plenty of information, namely mutation statistics and display, clickable sequences with mutations and changes to restriction enzyme patterns.
Description
More detailed information about this field from each metasource.
KinMutBase is a comprehensive database of disease-causing mutations in protein kinase domains. This resources provides plenty of information, namely mutation statistics and display, clickable sequences with mutations and changes to restriction enzyme patterns.
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
Webpage:
http://structure.bmc.lu.se/idbase/KinMutBase/Webpage
More detailed information about this field from each metasource.
http://structure.bmc.lu.se/idbase/KinMutBase/
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
KinMutBase: a registry of disease-causing mutations in protein kinase domains
PMID: 15832311
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
KinMutBase, a database of human disease-causing protein kinase mutations
PMID: 10592276
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
Publications
More detailed information about this field from each metasource.
KinMutBase: a registry of disease-causing mutations in protein kinase domains
PMID: 15832311
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
KinMutBase, a database of human disease-causing protein kinase mutations
PMID: 10592276
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
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KinMutBase: a registry of disease-causing mutations in protein kinase domains
PubMed citations: 32.
32 articles citing: KinMutBase: a registry of disease-causing mutations in protein kinase domains
CORR Insights®: Identification of a Novel MAN1A1-ROS1 Fusion Gene Through mRNA-based Screening for Tyrosine Kinase Gene Aberrations in a Patient with Leiomyosarcoma. PMID:33394756
Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources. PMID:32676006
Variation benchmark datasets: update, criteria, quality and applications. PMID:32016318
HKPocket: human kinase pocket database for drug design. PMID:31783725
PTMD: A Database of Human Disease-associated Post-translational Modifications. PMID:30244175
PON-P and PON-P2 predictor performance in CAGI challenges: Lessons learned. PMID:28224672
Kin-Driver: a database of driver mutations in protein kinases. PMID:25414382
ProKinO: a unified resource for mining the cancer kinome. PMID:25382819
Benchmarking infrastructure for mutation text mining. PMID:24568600
Literature mining of genetic variants for curation: quantifying the importance of supplementary material. PMID:24520105
wKinMut: an integrated tool for the analysis and interpretation of mutations in human protein kinases. PMID:24289158
EKPD: a hierarchical database of eukaryotic protein kinases and protein phosphatases. PMID:24214991
Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1. PMID:23498919
Interpretation of the consequences of mutations in protein kinases: combined use of bioinformatics and text mining. PMID:23055974
ProKinO: an ontology for integrative analysis of protein kinases in cancer. PMID:22194913
Expanding the conformational selection paradigm in protein-ligand docking. PMID:22183530
The energy landscape analysis of cancer mutations in protein kinases. PMID:21998754
The Roche Cancer Genome Database 2.0. PMID:21586118
Human SBK1 is dysregulated in multiple cancers and promotes survival of ovary cancer SK-OV-3 cells. PMID:21104019
Quantitative analysis of phosphorylation-based protein signaling networks in the immune system by mass spectrometry. PMID:20836078
Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases. PMID:20132407
Kinase mutations in human disease: interpreting genotype-phenotype relationships. PMID:20019687
Sequence and structure signatures of cancer mutation hotspots in protein kinases. PMID:19834613
Extraction of human kinase mutations from literature, databases and genotyping studies. PMID:19758464
Prediction of disease-related mutations affecting protein localization. PMID:19309509
Cancer driver mutations in protein kinase genes. PMID:19081671
MoKCa database--mutations of kinases in cancer. PMID:18986996
Kinomer v. 1.0: a database of systematically classified eukaryotic protein kinases. PMID:18974176
A helix scaffold for the assembly of active protein kinases. PMID:18787129
Congenital disease SNPs target lineage specific structural elements in protein kinases. PMID:18579784
Peptide-based fluorescent sensors of protein kinase activity: design and applications. PMID:17881302
Spectrum of disease-causing mutations in protein secondary structures. PMID:17727703 -
KinMutBase, a database of human disease-causing protein kinase mutations
PubMed citations: 9.
9 articles citing: KinMutBase, a database of human disease-causing protein kinase mutations
KinaseMD: kinase mutations and drug response database. PMID:33137204
HKPocket: human kinase pocket database for drug design. PMID:31783725
Evolution of protein kinase substrate recognition at the active site. PMID:31233486
Exploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration. PMID:27544236
A rational free energy-based approach to understanding and targeting disease-causing missense mutations. PMID:23408511
The energy landscape analysis of cancer mutations in protein kinases. PMID:21998754
Human SBK1 is dysregulated in multiple cancers and promotes survival of ovary cancer SK-OV-3 cells. PMID:21104019
Sequence and structure signatures of cancer mutation hotspots in protein kinases. PMID:19834613
Computational modeling of structurally conserved cancer mutations in the RET and MET kinases: the impact on protein structure, dynamics, and stability. PMID:19186126
Tags:
Tags
More detailed information about this field from each metasource.
disease
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
enzyme
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
genetic disorder
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
genetic polymorphism
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
mutation
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
protein
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
protein structure
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
polypeptide_region
metasource: Fairsharing.org
version: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
Tags
More detailed information about this field from each metasource.
disease
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
enzyme
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
genetic disorder
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
genetic polymorphism
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
mutation
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
protein
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
protein structure
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
polypeptide_region
metasource: Fairsharing.orgversion: FAIRsharing.org: KinMutBase; KinMutBase; DOI: https://doi.org/10.25504/FAIRsharing.q2ntvx; Last edited: April 26, 2021, 9:32 a.m.; Last accessed: Jan 03 2022 7:08 p.m.
disease enzyme genetic disorder polymorphism mutation protein protein structure polypeptide region
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