GeneNetwork
GeneNetwork is a group of linked data sets and tools used to study complex networks of genes, molecules, and higher order gene function and phenotypes. GeneNetwork combines more than 25 years of legacy data generated by hundreds of scientists together with sequence data (SNPs) and massive transcriptome data sets (expression or eQTL data sets). GeneNetwork was created in 1994 as The Portable Dictionary of the Mouse Genome, and became WebQTL in 2001. In 2005 it was renamed GeneNetwork.
Description
More detailed information about this field from each metasource.
GeneNetwork is a group of linked data sets and tools used to study complex networks of genes, molecules, and higher order gene function and phenotypes. GeneNetwork combines more than 25 years of legacy data generated by hundreds of scientists together with sequence data (SNPs) and massive transcriptome data sets (expression or eQTL data sets). GeneNetwork was created in 1994 as The Portable Dictionary of the Mouse Genome, and became WebQTL in 2001. In 2005 it was renamed GeneNetwork.
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Webpage:
http://www.genenetwork.org/Webpage
More detailed information about this field from each metasource.
http://www.genenetwork.org/
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior
PMID: 15114364
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
https://doi.org/10.21105/joss.00025
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications
More detailed information about this field from each metasource.
WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior
PMID: 15114364
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
https://doi.org/10.21105/joss.00025
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
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WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior
PubMed citations: 97.
97 articles citing: WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior
Ace2 and Tmprss2 Expressions Are Regulated by Dhx32 and Influence the Gastrointestinal Symptoms Caused by SARS-CoV-2. PMID:34834564
A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity. PMID:34677900
Speeding up eQTL scans in the BXD population using GPUs. PMID:34499130
Integration of evidence across human and model organism studies: A meeting report. PMID:33893716
A systems genetics approach to revealing the Pdgfb molecular network of the retina. PMID:32587457
Identifying gene function and module connections by the integration of multispecies expression compendia. PMID:31754022
Development of a tissue augmented Bayesian model for expression quantitative trait loci analysis. PMID:31731343
Genetic Influences on the Amount of Cell Death in the Neural Tube of BXD Mice Exposed to Acute Ethanol at Midgestation. PMID:30589433
Genetic differences in the behavioral organization of binge eating, conditioned food reward, and compulsive-like eating in C57BL/6J and DBA/2J strains. PMID:30261172
Genome-wide association for testis weight in the diversity outbred mouse population. PMID:29691636
Identification of quantitative trait loci associated with the susceptibility of mouse spermatozoa to cryopreservation. PMID:29269609
Gene Expression Networks in the Murine Pulmonary Myocardium Provide Insight into the Pathobiology of Atrial Fibrillation. PMID:28720711
GeneNetwork: A Toolbox for Systems Genetics. PMID:27933521
A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion. PMID:27829151
Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse. PMID:27399650
Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. PMID:27376237
Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test. PMID:27231153
Alterations in the expression of a neurodevelopmental gene exert long-lasting effects on cognitive-emotional phenotypes and functional brain networks: translational evidence from the stress-resilient Ahi1 knockout mouse. PMID:27021817
Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains. PMID:26948279
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice. PMID:26921172
Joint mouse-human phenome-wide association to test gene function and disease risk. PMID:26833085
Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity. PMID:26658939
Genetic properties of the MAGIC maize population: a new platform for high definition QTL mapping in Zea mays. PMID:26357913
The Convergence of Systems and Reductionist Approaches in Complex Trait Analysis. PMID:26140590
Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics. PMID:24923803
Genetic control of weight loss during pneumonic Burkholderia pseudomallei infection. PMID:24687986
Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice. PMID:24289814
Analyzing gene expression data in mice with the Neuro Behavior Ontology. PMID:24177753
Potential role of Atp5g3 in epigenetic regulation of alcohol preference or obesity from a mouse genomic perspective. PMID:24085430
Genome-wide gene expression profiles in antioxidant pathways and their potential sex differences and connections to vitamin C in mice. PMID:23665904
Measuring behavior of animal models: faults and remedies. PMID:23223171
Human disease: Strength to strength for mouse models. PMID:23222600
Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases. PMID:23209647
Genetic and molecular network analysis of behavior. PMID:23195314
Using genome-wide expression profiling to define gene networks relevant to the study of complex traits: from RNA integrity to network topology. PMID:23195313
Identifying gene networks underlying the neurobiology of ethanol and alcoholism. PMID:23134046
Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains. PMID:22974136
Systems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits. PMID:22939713
Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner. PMID:22905720
Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-chain dicarboxylic acids. PMID:22534643
Congenic dissection of a major QTL for methamphetamine sensitivity implicates epistasis. PMID:22487465
Systems genetic analysis of the effects of iron deficiency in mouse brain. PMID:22457016
Anakinra as an interleukin 1 receptor antagonist, complicated genetics and molecular impacts--from the point of view of mouse genomics. PMID:22425556
Accelerating discovery for complex neurological and behavioral disorders through systems genetics and integrative genomics in the laboratory mouse. PMID:22422471
Behavioral actions of alcohol: phenotypic relations from multivariate analysis of mutant mouse data. PMID:22405477
Characterization of Genetic Differences within the Centrally Projecting Edinger-Westphal Nucleus of C57BL/6J and DBA/2J Mice by Expression Profiling. PMID:22347848
Candidate genes in ocular dominance plasticity. PMID:22347157
The genome architecture of the Collaborative Cross mouse genetic reference population. PMID:22345608
Genome-wide association for fear conditioning in an advanced intercross mouse line. PMID:22237917
Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease. PMID:22182475
Genome-wide association for methamphetamine sensitivity in an advanced intercross mouse line. PMID:22032291
Genetic networks in the mouse retina: growth associated protein 43 and phosphatase tensin homolog network. PMID:21655357
Anxiety and fear in a cross of C57BL/6J and DBA/2J mice: mapping overlapping and independent QTL for related traits. PMID:21554534
Genome-wide analysis of the mouse lung transcriptome reveals novel molecular gene interaction networks and cell-specific expression signatures. PMID:21535883
Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation. PMID:21494628
Genetic dissection of behavioral flexibility: reversal learning in mice. PMID:21392734
Dissecting genetic networks underlying complex phenotypes: the theoretical framework. PMID:21283795
Genomic loci and candidate genes underlying inflammatory nociception. PMID:21195549
Appetitive operant conditioning in mice: heritability and dissociability of training stages. PMID:21119771
Using expression genetics to study the neurobiology of ethanol and alcoholism. PMID:20813241
A transposon in Comt generates mRNA variants and causes widespread expression and behavioral differences among mice. PMID:20808911
Identifying Genomic Regulators of Set-Wise Co-Expression. PMID:20651944
High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. PMID:19958391
Expression quantitative trait loci are highly sensitive to cellular differentiation state. PMID:19834560
Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. PMID:19727342
A major QTL on chromosome 11 influences psychostimulant and opioid sensitivity in mice. PMID:19694818
The genetic control of neocortex volume and covariation with neocortical gene expression in mice. PMID:19426526
Intra- and inter-individual genetic differences in gene expression. PMID:19424753
Genetic modulation of striatal volume by loci on Chrs 6 and 17 in BXD recombinant inbred mice. PMID:19191878
Cost-effective strategies for completing the interactome. PMID:19079254
Towards systems genetic analyses in barley: Integration of phenotypic, expression and genotype data into GeneNetwork. PMID:19017390
Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight. PMID:18817551
Using hippocampal microRNA expression differences between mouse inbred strains to characterise miRNA function. PMID:18594913
Combining transcriptional profiling and genetic linkage analysis to uncover gene networks operating in hematopoietic stem cells and their progeny. PMID:18560825
SGDI: system for genomic data integration. PMID:18229682
Gene expression profiling of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading: identification of transcriptional regulatory targets of Hfe and potential hemochromatosis modifiers. PMID:17945001
A simple method for combining genetic mapping data from multiple crosses and experimental designs. PMID:17940600
Integrating physical and genetic maps: from genomes to interaction networks. PMID:17703239
Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources. PMID:17436037
Quantitative trait loci linked to thalamus and cortex gray matter volumes in BXD recombinant inbred mice. PMID:17406662
Transcriptional profiling of C57 and DBA strains of mice in the absence and presence of morphine. PMID:17367521
PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits. PMID:17099235
Design of microarray experiments for genetical genomics studies. PMID:16888340
Extracting gene networks for low-dose radiation using graph theoretical algorithms. PMID:16854212
How replicable are mRNA expression QTL? PMID:16783644
Prediction of cis-QTLs in a pair of inbred mouse strains with the use of expression and haplotype data from public databases. PMID:16783643
Integrated gene expression profiling and linkage analysis in the rat. PMID:16783629
Gene expression profiling in the striatum of inbred mouse strains with distinct opioid-related phenotypes. PMID:16772024
Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors. PMID:16723524
Genetic control of hippocampal neurogenesis. PMID:16584531
Genetic networks controlling retinal injury. PMID:16288200
Gene expression differences in mice divergently selected for methamphetamine sensitivity. PMID:16104378
A statistical multiprobe model for analyzing cis and trans genes in genetical genomics experiments with short-oligonucleotide arrays. PMID:16079228
Computational, integrative, and comparative methods for the elucidation of genetic coexpression networks. PMID:16046823
WebGestalt: an integrated system for exploring gene sets in various biological contexts. PMID:15980575
Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli. PMID:15967025
Weighting by heritability for detection of quantitative trait loci with microarray estimates of gene expression. PMID:15774028 - https://doi.org/10.21105/joss.00025
Tags:
Tags
More detailed information about this field from each metasource.
gene expression
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
gene expression data
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
genotype
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
network model
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
phenotype
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
quantitative trait loci
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
single nucleotide polymorphism
metasource: Fairsharing.org
version: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Tags
More detailed information about this field from each metasource.
gene expression
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
gene expression data
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
genotype
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
network model
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
phenotype
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
quantitative trait loci
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
single nucleotide polymorphism
metasource: Fairsharing.orgversion: FAIRsharing.org: GeneNetwork; GeneNetwork; DOI: https://doi.org/10.25504/FAIRsharing.dt71b7; Last edited: May 12, 2020, 12:40 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
gene expression gene expression genotype network model phenotype quantitative trait loci single nucleotide polymorphism
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