Bitter Compounds Database
Names
More detailed information about this field from each metasource.
Bitter Compounds Database
metasource: Fairsharing.org
version: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
BitterDB
metasource: Fairsharing.org
version: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Names
More detailed information about this field from each metasource.
Bitter Compounds Database
metasource: Fairsharing.orgversion: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
BitterDB
metasource: Fairsharing.orgversion: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Names
More detailed information about this field from each metasource.
Bitter Compounds Database
metasource: Fairsharing.orgversion: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
BitterDB
metasource: Fairsharing.orgversion: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
BitterDB is a free and searchable database of bitter compounds. Compounds can be searched by name, chemical structure, similarity to other bitter compounds, association with a particular human bitter taste receptor, and so on. The database also contains information on mutations in bitter taste re- ceptors that were shown to influence receptor activation by bitter compounds. The aim of BitterDB is to facilitate studying the chemical features associated with bitterness.
Description
More detailed information about this field from each metasource.
BitterDB is a free and searchable database of bitter compounds. Compounds can be searched by name, chemical structure, similarity to other bitter compounds, association with a particular human bitter taste receptor, and so on. The database also contains information on mutations in bitter taste re- ceptors that were shown to influence receptor activation by bitter compounds. The aim of BitterDB is to facilitate studying the chemical features associated with bitterness.
metasource: Fairsharing.orgversion: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Bitter taste: molecules and receptors
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Webpage:
http://bitterdb.agri.huji.ac.il/bitterdb/dbbitter.phpWebpage
More detailed information about this field from each metasource.
http://bitterdb.agri.huji.ac.il/bitterdb/dbbitter.php
metasource: Fairsharing.orgversion: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://bitterdb.agri.huji.ac.il/dbbitter.php
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Licence:
Name: Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0)Licence name
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Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0)
metasource: Fairsharing.orgversion: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Licence URL
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https://creativecommons.org/licenses/by-nc-sa/3.0/
metasource: Fairsharing.orgversion: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
BitterDB: a database of bitter compounds
PMID: 21940398
metasource: Fairsharing.org
version: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/GKR755
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
BitterDB: a database of bitter compounds
PMID: 21940398
metasource: Fairsharing.org
version: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/GKR755
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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BitterDB: a database of bitter compounds
PubMed citations: 71.
71 articles citing: BitterDB: a database of bitter compounds
Identify Bitter Peptides by Using Deep Representation Learning Features. PMID:35887225
A survey on computational taste predictors. PMID:35637881
HSP90 Modulates T2R Bitter Taste Receptor Nitric Oxide Production and Innate Immune Responses in Human Airway Epithelial Cells and Macrophages. PMID:35563784
PlantMolecularTasteDB: A Database of Taste Active Phytochemicals. PMID:35095484
Tartary Buckwheat: A New Plant-Based Ingredient to Enrich Corn-Based Gluten-Free Formulations. PMID:34828896
Chemoinformatics View on Bitter Taste Receptor Agonists in Food. PMID:34762411
T2R bitter taste receptors regulate apoptosis and may be associated with survival in head and neck squamous cell carcinoma. PMID:34717036
An update on extra-oral bitter taste receptors. PMID:34674725
Bitter Taste and Olfactory Receptors: Beyond Chemical Sensing in the Tongue and the Nose. PMID:34173018
Evolutionary shifts in taste coding in the fruit pest Drosophila suzukii. PMID:33616529
Intense bitterness of molecules: Machine learning for expediting drug discovery. PMID:33510862
FlavorGraph: a large-scale food-chemical graph for generating food representations and recommending food pairings. PMID:33441585
Modulation of Food Intake by Differential TAS2R Stimulation in Rat. PMID:33321802
RecipeDB: a resource for exploring recipes. PMID:33238002
Quantitative prediction of the bitterness of atomoxetine hydrochloride and taste-masked using hydroxypropyl-β-cyclodextrin: A biosensor evaluation and interaction study. PMID:32952672
Beer and Consumer Response Using Biometrics: Associations Assessment of Beer Compounds and Elicited Emotions. PMID:32580405
Bitter taste receptors stimulate phagocytosis in human macrophages through calcium, nitric oxide, and cyclic-GMP signaling. PMID:32172302
Molecular Logic and Evolution of Bitter Taste in Drosophila. PMID:31839451
TAS2R38 bitter taste receptor and attainment of exceptional longevity. PMID:31792278
Effect of Bitter Compounds on the Expression of Bitter Taste Receptor T2R7 Downstream Signaling Effectors in cT2R7/pDisplay-Gα16/gust44/pcDNA3.1 (+) Cells. PMID:31781630
Regional Variation of Bitter Taste and Aftertaste in Humans. PMID:31541607
Bitter tastants and artificial sweeteners activate a subset of epithelial cells in acute tissue slices of the rat trachea. PMID:31222082
Mechanisms Underlying the Anti-Depressive Effects of Regular Tea Consumption. PMID:31212946
Influences of Psychological Traits and PROP Taster Status on Familiarity with and Choice of Phenol-Rich Foods and Beverages. PMID:31200523
Dual binding mode of "bitter sugars" to their human bitter taste receptor target. PMID:31186454
A natural point mutation in the bitter taste receptor TAS2R16 causes inverse agonism of arbutin in lemur gustation. PMID:31161904
BitterSweet: Building machine learning models for predicting the bitter and sweet taste of small molecules. PMID:31073241
Beyond the Flavour: The Potential Druggability of Chemosensory G Protein-Coupled Receptors. PMID:30897734
e-Sweet: A Machine-Learning Based Platform for the Prediction of Sweetener and Its Relative Sweetness. PMID:30761295
BitterDB: taste ligands and receptors database in 2019. PMID:30357384
Identification of bitter components from Artemisia princeps Pamp. PMID:30263232
PhytoMolecularTasteDB: An integrative database on the "molecular taste" of Indian medicinal plants. PMID:30246068
In silico design of novel proton-pump inhibitors with reduced adverse effects. PMID:29845582
BitterSweetForest: A Random Forest Based Binary Classifier to Predict Bitterness and Sweetness of Chemical Compounds. PMID:29696137
e-Bitter: Bitterant Prediction by the Consensus Voting From the Machine-Learning Methods. PMID:29651416
The Role of Quinine-Responsive Taste Receptor Family 2 in Airway Immune Defense and Chronic Rhinosinusitis. PMID:29643854
Taste Receptor Polymorphisms and Immune Response: A Review of Receptor Genotypic-Phenotypic Variations and Their Relevance to Chronic Rhinosinusitis. PMID:29564227
Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes. PMID:29552563
Molecular Features Underlying Selectivity in Chicken Bitter Taste Receptors. PMID:29445727
Biomimetic Sensors for the Senses: Towards Better Understanding of Taste and Odor Sensation. PMID:29232897
Bitter Taste Responses of Gustducin-positive Taste Cells in Mouse Fungiform and Circumvallate Papillae. PMID:29113930
FlavorDB: a database of flavor molecules. PMID:29059383
Identification of a specific agonist of human TAS2R14 from Radix Bupleuri through virtual screening, functional evaluation and binding studies. PMID:28939897
Bitter or not? BitterPredict, a tool for predicting taste from chemical structure. PMID:28935887
The human bitter taste receptor T2R38 is broadly tuned for bacterial compounds. PMID:28902853
Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case. PMID:28811548
Extraoral Taste Receptor Discovery: New Light on Ayurvedic Pharmacology. PMID:28642799
From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. PMID:28513558
Anti-cancer stemness and anti-invasive activity of bitter taste receptors, TAS2R8 and TAS2R10, in human neuroblastoma cells. PMID:28467517
Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor. PMID:28373278
Immunopathogenesis of Chronic Rhinosinusitis and Nasal Polyposis. PMID:27959637
Variation in ligand responses of the bitter taste receptors TAS2R1 and TAS2R4 among New World monkeys. PMID:27733116
Correlation of T2R38 taste phenotype and in vitro biofilm formation from nonpolypoid chronic rhinosinusitis patients. PMID:27309535
Comprehensive Analysis of Mouse Bitter Taste Receptors Reveals Different Molecular Receptive Ranges for Orthologous Receptors in Mice and Humans. PMID:27226572
Regulation of Adipogenesis by Quinine through the ERK/S6 Pathway. PMID:27089323
BitterX: a tool for understanding bitter taste in humans. PMID:27040075
GPCRdb: an information system for G protein-coupled receptors. PMID:26582914
Modulation of the Bitter Taste to Reduce Calorie Intake. PMID:26424036
The Bitter Taste Receptor Agonist Quinine Reduces Calorie Intake and Increases the Postprandial Release of Cholecystokinin in Healthy Subjects. PMID:26351252
Development of a molecular method for the rapid screening and identification of the three functionally relevant polymorphisms in the human TAS2R38 receptor gene in studies of sensitivity to the bitter taste of PROP. PMID:26090297
Sequence Analysis of Bitter Taste Receptor Gene Repertoires in Different Ruminant Species. PMID:26061084
A functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs. PMID:26037485
Physical approaches to masking bitter taste: lessons from food and pharmaceuticals. PMID:25205460
Expanding the fragrance chemical space for virtual screening. PMID:24876890
Bitter and sweet taste receptors regulate human upper respiratory innate immunity. PMID:24531552
Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity. PMID:24117140
GWAS of human bitter taste perception identifies new loci and reveals additional complexity of bitter taste genetics. PMID:23966204
Prodrugs for masking bitter taste of antibacterial drugs--a computational approach. PMID:23420399
The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands. PMID:23283334
Bitter taste receptor polymorphisms and human aging. PMID:23133589
Responsiveness to 6-n-propylthiouracil (PROP) is associated with salivary levels of two specific basic proline-rich proteins in humans. PMID:22312435 - http://dx.doi.org/10.1093/nar/GKR755
Tags:
Tags
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receptor
metasource: Fairsharing.org
version: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
structure databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
small molecules
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Tags
More detailed information about this field from each metasource.
receptor
metasource: Fairsharing.orgversion: FAIRsharing.org: BitterDB; Bitter Compounds Database; DOI: https://doi.org/10.25504/FAIRsharing.d8bfx4; Last edited: Jan. 8, 2019, 1:12 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
structure databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
small molecules
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
receptor structure small molecule
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