Interleukins 4 and 21 Protect Anti-IgM Induced Cell Death in Ramos B Cells: Implication for Autoimmune Diseases.
PMID:35911775
RNA Sequencing of the Pituitary Gland and Association Analyses Reveal PRKG2 as a Candidate Gene for Growth and Carcass Traits in Chinese Ningdu Yellow Chickens.
PMID:35782572
Immune Response to Microsporidia.
PMID:35544009
Blimp-1 molds the epigenetic architecture of IL-21-mediated autoimmune diseases through an autoregulatory circuit.
PMID:35503415
Molecular Mechanisms Driving IL-10- Producing B Cells Functions: STAT3 and c-MAF as Underestimated Central Key Regulators?
PMID:35359922
STAT3 Role in T-Cell Memory Formation.
PMID:35270020
Conserved and Unique Functions of Blimp1 in Immune Cells.
PMID:35154079
Naive and memory CD4+ T cell subsets can contribute to the generation of human Tfh cells.
PMID:34984326
Patient-Specific Modeling of Diffuse Large B-Cell Lymphoma.
PMID:34829885
Single-cell RNA-Seq reveals transcriptional heterogeneity and immune subtypes associated with disease activity in human myasthenia gravis.
PMID:34521820
Germline STAT3 gain-of-function mutations in primary immunodeficiency: Impact on the cellular and clinical phenotype.
PMID:34366294
Re-Programming Autoreactive T Cells Into T-Regulatory Type 1 Cells for the Treatment of Autoimmunity.
PMID:34335585
Metformin as a Treatment Strategy for Sjögren's Syndrome.
PMID:34281285
Biology of Germinal Center B Cells Relating to Lymphomagenesis.
PMID:34095765
The diversity of the plasmablast signature across species and experimental conditions: A meta-analysis.
PMID:34041745
T-bet+CD27+CD21- B cells poised for plasma cell differentiation during antibody-mediated rejection of kidney transplants.
PMID:34032636
Interferon regulatory factor 4 controls effector functions of CD8+ memory T cells.
PMID:33859042
Comparative Analysis of Global Proteome and Lysine Acetylome Between Naive CD4+ T Cells and CD4+ T Follicular Helper Cells.
PMID:33841426
Gamma-Chain Receptor Cytokines & PD-1 Manipulation to Restore HCV-Specific CD8+ T Cell Response during Chronic Hepatitis C.
PMID:33802622
SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself.
PMID:33785765
Bcl6-Mediated Transcriptional Regulation of Follicular Helper T cells (TFH).
PMID:33663954
Stepwise Tfh cell differentiation revisited: new advances and long-standing questions.
PMID:33644779
Multiscale Modeling of Germinal Center Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells Differentiation as Regulated by Antigen Affinity-Based Tfh Cell Help.
PMID:33613551
Conversations that count: Cellular interactions that drive T cell fate.
PMID:33586207
IL-21 enhances STAT3/Blimp-1 signaling pathway in B cells and contributes to plasma cell differentiation in newly diagnosed patients with myasthenia gravis.
PMID:33145710
IL-21 in Homeostasis of Resident Memory and Exhausted CD8 T Cells during Persistent Infection.
PMID:32971931
The Impact of Malaria Parasites on Dendritic Cell-T Cell Interaction.
PMID:32793231
Repression of the B cell identity factor Pax5 is not required for plasma cell development.
PMID:32780801
A Synchronous IRF4-Dependent Gene Regulatory Network in B and Helper T Cells Orchestrating the Antibody Response.
PMID:32467029
T Follicular Helper Cell Subsets and the Associated Cytokine IL-21 in the Pathogenesis and Therapy of Asthma.
PMID:31921177
Cytokines in the Germinal Center Niche.
PMID:31557986
Interleukin 21 Receptor/Ligand Interaction Is Linked to Disease Progression in Pancreatic Cancer.
PMID:31540511
Survival of Long-Lived Plasma Cells (LLPC): Piecing Together the Puzzle.
PMID:31130955
IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus.
PMID:30969166
Function and dysfunction of plasma cells in intestine.
PMID:30911371
Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation.
PMID:30759395
Chromatin Accessibility and Interactions in the Transcriptional Regulation of T Cells.
PMID:30524449
Tipping the balance: inhibitory checkpoints in intestinal homeostasis.
PMID:30498201
Precocious expression of Blimp1 in B cells causes autoimmune disease with increased self-reactive plasma cells.
PMID:30498131
ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells.
PMID:30413785
Molecular Control of Follicular Helper T cell Development and Differentiation.
PMID:30410493
IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection.
PMID:30364284
Notch2-dependent DC2s mediate splenic germinal center responses.
PMID:30279176
Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis.
PMID:30177845
Insights Into the Molecular Mechanisms of T Follicular Helper-Mediated Immunity and Pathology.
PMID:30158933
ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.
PMID:29449309
STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus.
PMID:29078395
The Common Cytokine Receptor γ Chain Family of Cytokines.
PMID:29038115
New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function.
PMID:28732506
Metabolic Regulation of the Immune Humoral Response.
PMID:28514675
Germinal center B cell development has distinctly regulated stages completed by disengagement from T cell help.
PMID:28498098
Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1.
PMID:28439269
Mechanisms and consequences of Jak-STAT signaling in the immune system.
PMID:28323260
Metformin Suppresses Systemic Autoimmunity in Roquinsan/san Mice through Inhibiting B Cell Differentiation into Plasma Cells via Regulation of AMPK/mTOR/STAT3.
PMID:28242651
Genome-Wide STAT3 Binding Analysis after Histone Deacetylase Inhibition Reveals Novel Target Genes in Dendritic Cells.
PMID:27866206
STAT1 regulates marginal zone B cell differentiation in response to inflammation and infection with blood-borne bacteria.
PMID:27849553
The transcription factor network in Th9 cells.
PMID:27837254
Interferon Regulatory Factor 4 controls TH1 cell effector function and metabolism.
PMID:27762344
Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity.
PMID:27670590
Synergistic activity of Card11 mutant and Bcl6 in the development of diffuse large B-cell lymphoma in a mouse model.
PMID:27560392
Ablation of STAT3 in the B Cell Compartment Restricts Gammaherpesvirus Latency In Vivo.
PMID:27486189
ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings.
PMID:27436361
IL-21 and T Cell Differentiation: Consider the Context.
PMID:27389961
Insights into the development and regulation of T follicular helper cells.
PMID:27339151
Human Th17 Cells Lack HIV-Inhibitory RNases and Are Highly Permissive to Productive HIV Infection.
PMID:27334595
Advances of the interleukin-21 signaling pathway in immunity and angiogenesis.
PMID:27330746
Isoform-specific targeting of ROCK proteins in immune cells.
PMID:27254302
The curious origins of angioimmunoblastic T-cell lymphoma.
PMID:27177312
IL-21 Signaling in Immunity.
PMID:26966515
The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6.
PMID:26957522
A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet.
PMID:26950239
Reactivation of IgG-switched memory B cells by BCR-intrinsic signal amplification promotes IgG antibody production.
PMID:26815242
Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation.
PMID:26779602
Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response.
PMID:26779600
A Network Model to Describe the Terminal Differentiation of B Cells.
PMID:26751566
Identification of a gain-of-function STAT3 mutation (p.Y640F) in lymphocytic variant hypereosinophilic syndrome.
PMID:26702067
Common gamma chain cytokines in combinatorial immune strategies against cancer.
PMID:26597610
Regulatory T Cell Induction and Retention in the Lungs Drives Suppression of Detrimental Type 2 Th Cells During Pulmonary Cryptococcal Infection.
PMID:26590316
The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development.
PMID:26329582
Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells.
PMID:26305332
The forkhead transcription factor FOXP1 represses human plasma cell differentiation.
PMID:26289642
Synchronizing transcriptional control of T cell metabolism and function.
PMID:26272293
Poly-ADP-ribosyl polymerase-14 promotes T helper 17 and follicular T helper development.
PMID:26222149
Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells.
PMID:26170288
IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection.
PMID:26108174
Early Growth Response Genes 2 and 3 Regulate the Expression of Bcl6 and Differentiation of T Follicular Helper Cells.
PMID:25979336
IL-21: a pleiotropic cytokine with potential applications in oncology.
PMID:25961061
Effector CD8 T cell immunity in microsporidial infection: a lone defense mechanism.
PMID:25860800
The oncogenic transcription factor IRF4 is regulated by a novel CD30/NF-κB positive feedback loop in peripheral T-cell lymphoma.
PMID:25833963
T-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significance.
PMID:25789969
Germinal centres and B cell lymphomagenesis.
PMID:25712152
The generation of antibody-secreting plasma cells.
PMID:25698678
Factors regulating immunoglobulin production by normal and disease-associated plasma cells.
PMID:25615546
The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.
PMID:25599561
Mechanisms of Jak/STAT signaling in immunity and disease.
PMID:25527793
IRF4 and IRF8: Governing the virtues of B Lymphocytes.
PMID:25506356
Adipocyte-specific IKKβ signaling suppresses adipose tissue inflammation through an IL-13-dependent paracrine feedback pathway.
PMID:25466256
The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.
PMID:25288399
The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells.
PMID:25288397
Gene expression profiling identifies IRF4-associated molecular signatures in hematological malignancies.
PMID:25207815
Complex interactions of transcription factors in mediating cytokine biology in T cells.
PMID:25123282
Transcriptional and epigenetic networks of helper T and innate lymphoid cells.
PMID:25123275
The murine gammaherpesvirus immediate-early Rta synergizes with IRF4, targeting expression of the viral M1 superantigen to plasma cells.
PMID:25101696
Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1.
PMID:25003188
IRF4 is a key thermogenic transcriptional partner of PGC-1α.
PMID:24995979
The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells.
PMID:24859450
Transcriptional regulatory networks for CD4 T cell differentiation.
PMID:24839135
PRDM Proteins: Molecular Mechanisms in Signal Transduction and Transcriptional Regulation.
PMID:24832654
Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes.
PMID:24831346
Exploring the IL-21-STAT3 axis as therapeutic target for Sézary syndrome.
PMID:24756111
Interleukin-21: a double-edged sword with therapeutic potential.
PMID:24751819
The transcriptional modulator BCL6 as a molecular target for breast cancer therapy.
PMID:24662818
Insights into the role of follicular helper T cells in autoimmunity.
PMID:24605077
Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression.
PMID:24590764
Expansion or depletion of T follicular helper cells during HIV infection: consequences for B cell responses.
PMID:24568615
Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program.
PMID:24489092
IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells.
PMID:24470500
Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development.
PMID:24463518
Genomic and computational approaches to dissect the mechanisms of STAT3's universal and cell type-specific functions.
PMID:24416643
Large-scale quality analysis of published ChIP-seq data.
PMID:24347632
Evaluation of STAT5A Gene Expression in Aflatoxin B1 Treated Bovine Mammary Epithelial Cells.
PMID:24312879
Genome-scale technology driven advances to research into normal and malignant haematopoiesis.
PMID:24278696
Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation.
PMID:24211184
Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.
PMID:24200695
From a gene-centric to whole-proteome view of differentiation of T helper cell subsets.
PMID:24106101
The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells.
PMID:24056747
The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells.
PMID:23980171
The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges.
PMID:23943603
The unique features of follicular T cell subsets.
PMID:23852544
Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T-cell memory formation and function.
PMID:23830147
The Emerging Role of Interleukin-21 in Transplantation.
PMID:23828737
Bach2 maintains T cells in a naive state by suppressing effector memory-related genes.
PMID:23754397
Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells.
PMID:23688737
Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease.
PMID:23622118
B-lymphocyte lineage cells and the respiratory system.
PMID:23540615
ChIP-PED enhances the analysis of ChIP-seq and ChIP-chip data.
PMID:23457041
The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells.
PMID:23453633
Transcriptional regulation of follicular T-helper (Tfh) cells.
PMID:23405901
Helper T-cell identity and evolution of differential transcriptomes and epigenomes.
PMID:23405893
T follicular helper cell diversity and plasticity.
PMID:23395212
IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells.
PMID:23325890
Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules.
PMID:23324445
Synthetic cationic peptide IDR-1018 modulates human macrophage differentiation.
PMID:23308112
Distinct transcriptional regulatory modules underlie STAT3's cell type-independent and cell type-specific functions.
PMID:23295670
Anti-viral CD8 T cells and the cytokines that they love.
PMID:23217625
Immunology. Cooperative transcription factor complexes in control.
PMID:23161983
Transcriptional control of effector and memory CD8+ T cell differentiation.
PMID:23080391
STAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis.
PMID:23066027
B lymphocyte-induced maturation protein 1 (BLIMP-1) attenuates autoimmune diabetes in NOD mice by suppressing Th1 and Th17 cells.
PMID:23052053
B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1.
PMID:23045607
A validated regulatory network for Th17 cell specification.
PMID:23021777
BATF-JUN is critical for IRF4-mediated transcription in T cells.
PMID:22992523
A genomic regulatory element that directs assembly and function of immune-specific AP-1-IRF complexes.
PMID:22983707
Down syndrome, autoimmunity and T regulatory cells.
PMID:22861363
The origins, function, and regulation of T follicular helper cells.
PMID:22753927
Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell.
PMID:22745171
Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation.
PMID:22552227
Inborn errors of human JAKs and STATs.
PMID:22520845
The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.
PMID:22466669
Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.
PMID:22464170
Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity.
PMID:22370718
STAT5 is a potent negative regulator of TFH cell differentiation.
PMID:22271576
Genome-wide identification and annotation of HIF-1α binding sites in two cell lines using massively parallel sequencing.
PMID:22132063
SOCS3 deletion in B cells alters cytokine responses and germinal center output.
PMID:22075701
In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo.
PMID:21897376
CD8(+) T cells: foot soldiers of the immune system.
PMID:21867926
Interpreting mixed signals: the cell's cytokine conundrum.
PMID:21852079
The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications.
PMID:21752875
Germinal center B and follicular helper T cells: siblings, cousins or just good friends?
PMID:21739669
Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation.
PMID:21715693
Application of ChIP-Seq and related techniques to the study of immune function.
PMID:21703538
The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells.
PMID:21572431
Genomic views of STAT function in CD4+ T helper cell differentiation.
PMID:21436836
IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (Tfh) differentiation.
PMID:21423809
The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells.
PMID:21378976
Cytokines and the inception of CD8 T cell responses.
PMID:21371940
Phenotypical and functional specialization of FOXP3+ regulatory T cells.
PMID:21267013
Kitasato Symposium 2010: new prospects for cytokines.
PMID:21235827
Plasma cells negatively regulate the follicular helper T cell program.
PMID:21037578
IL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infection.
PMID:20844201
A unique H3K4me2 profile marks tissue-specific gene regulation.
PMID:20841431
Interleukin-21: a multifunctional regulator of immunity to infections.
PMID:20817119
Epigenetic down-regulation of the tumor suppressor gene PRDM1/Blimp-1 in diffuse large B cell lymphomas: a potential role of the microRNA let-7.
PMID:20651244
Effector T cell plasticity: flexibility in the face of changing circumstances.
PMID:20644573
Generation of effector CD8+ T cells and their conversion to memory T cells.
PMID:20636815
Understanding the development and function of T follicular helper cells.
PMID:20383172
Shaping successful and unsuccessful CD8 T cell responses following infection.
PMID:20379363
T-cell exhaustion: characteristics, causes and conversion.
PMID:20201977