Yeast GFP fusion localization database (yeastgfp)

Names
More detailed information about this field from each metasource.

Yeast GFP fusion localization database (yeastgfp)
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:42.490315

yeastgfp
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:42.490315

Other names: yeastgfp

Yeast GFP fusion localization database.

Webpage:

http://yeastgfp.yeastgenome.org/

Publications:

Publications
More detailed information about this field from each metasource.

Global analysis of protein localization in budding yeast
PMID: 14562095
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:42.490315

Global analysis of protein localization in budding yeast PubMed citations: 1912.

1912 articles citing: Global analysis of protein localization in budding yeast

Proximity-Dependent Biotinylation Approaches to Explore the Dynamic Compartmentalized Proteome. PMID:35309513
Intrinsically disordered signaling proteins: Essential hub players in the control of stress responses in Saccharomyces cerevisiae. PMID:35290420
Tom70-based transcriptional regulation of mitochondrial biogenesis and aging. PMID:35234609
The Association of Rpb4 with RNA Polymerase II Depends on CTD Ser5P Phosphatase Rtr1 and Influences mRNA Decay in Saccharomyces cerevisiae. PMID:35216121
Parameterising Translational Feedback Models of Autoregulatory RNA-Binding Proteins in Saccharomyces cerevisiae. PMID:35208795
Condensate Formation by Metabolic Enzymes in Saccharomyces cerevisiae. PMID:35208686
Interaction of TOR and PKA Signaling in S. cerevisiae. PMID:35204711
Xrn1 is a deNADding enzyme modulating mitochondrial NAD-capped RNA. PMID:35173156
TORC1 inactivation promotes APC/C-dependent mitotic slippage in yeast and human cells. PMID:35141499
SWI/SNF senses carbon starvation with a pH-sensitive low-complexity sequence. PMID:35129437
ScreenGarden: a shinyR application for fast and easy analysis of plate-based high-throughput screens. PMID:35123390
Subcellular Proteomics as a Unified Approach of Experimental Localizations and Computed Prediction Data for Arabidopsis and Crop Plants. PMID:35113396
Epi-Decoder: Decoding the Local Proteome of a Genomic Locus by Massive Parallel Chromatin Immunoprecipitation Combined with DNA-Barcode Sequencing. PMID:35103966
Mutant libraries reveal negative design shielding proteins from supramolecular self-assembly and relocalization in cells. PMID:35078932
Amino Acid Sensing and Assimilation by the Fungal Pathogen Candida albicans in the Human Host. PMID:35055954
Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing. PMID:35051350
Ageing exacerbates ribosome pausing to disrupt cotranslational proteostasis. PMID:35046576
The Effect of Dia2 Protein Deficiency on the Cell Cycle, Cell Size, and Recruitment of Ctf4 Protein in Saccharomyces cerevisiae. PMID:35011329
Cytosolic Quality Control of Mitochondrial Protein Precursors-The Early Stages of the Organelle Biogenesis. PMID:35008433
Synthesis and Evaluation of a Library of Alternating Amphipathic Copolymers to Solubilize and Study Membrane Proteins. PMID:34994549
High-Throughput Analysis of Protein Turnover with Tandem Fluorescent Protein Timers. PMID:34985695
Transcriptome analysis of Leucojum aestivum and identification of genes involved in norbelladine biosynthesis. PMID:34981205
Polarization modulation with optical lock-in detection reveals universal fluorescence anisotropy of subcellular structures in live cells. PMID:34974519
An Improved Memetic Algorithm for Detecting Protein Complexes in Protein Interaction Networks. PMID:34970305
Hormonal Regulatory Patterns of LaKNOXs and LaBEL1 Transcription Factors Reveal Their Potential Role in Stem Bulblet Formation in LA Hybrid Lily. PMID:34948303
Differential Requirement for the Cell Wall Integrity Sensor Wsc1p in Diploids Versus Haploids. PMID:34947031
Deepening into Intracellular Signaling Landscape through Integrative Spatial Proteomics and Transcriptomics in a Lymphoma Model. PMID:34944421
Retromer Complex and PI3K Complex II-Related Genes Mediate the Yeast (Saccharomyces cerevisiae) Sodium Metabisulfite Resistance Response. PMID:34944020
Research on the Computational Prediction of Essential Genes. PMID:34938741
Subcellular Transcriptomics and Proteomics: A Comparative Methods Review. PMID:34922010
Protein pI and Intracellular Localization. PMID:34912847
Forced association of SARS-CoV-2 proteins with the yeast proteome perturb vesicle trafficking. PMID:34909432
Endocytic proteins with prion-like domains form viscoelastic condensates that enable membrane remodeling. PMID:34887356
VID22 counteracts G-quadruplex-induced genome instability. PMID:34871443
The Flo Adhesin Family. PMID:34832553
Localization and Functional Roles of Components of the Translation Apparatus in the Eukaryotic Cell Nucleus. PMID:34831461
The Rpd3-Complex Regulates Expression of Multiple Cell Surface Recycling Factors in Yeast. PMID:34830359
Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation. PMID:34798055
Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging. PMID:34791226
Multiple epistatic DNA variants in a single gene affect gene expression in trans. PMID:34791209
Lack of evidence for condensin or cohesin sequestration on lipid droplets with packing defects. PMID:34746685
Simple-to-use CRISPR-SpCas9/SaCas9/AsCas12a vector series for genome editing in Saccharomyces cerevisiae. PMID:34739076
Microscopy analysis of the smallest subunit of the RPA complex, Rfa3p, prompts consideration of how RPA subunits gather at single-stranded DNA sites. PMID:34723142
Gds1 Interacts with NuA4 To Promote H4 Acetylation at Ribosomal Protein Genes. PMID:34694912
Genome tagging project: tag every protein in mice through 'artificial spermatids'. PMID:34691888
Compartmentalization and metabolic regulation of glycolysis. PMID:34668544
Proteomic analysis of dietary restriction in yeast reveals a role for Hsp26 in replicative lifespan extension. PMID:34661239
Molecular Characterization of a Tolerant Saline-Alkali Chlorella Phosphatidate Phosphatase That Confers NaCl and Sorbitol Tolerance. PMID:34650539
Dependence of Graphene Oxide (GO) Toxicity on Oxidation Level, Elemental Composition, and Size. PMID:34638921
A preferred sequence for organelle inheritance during polarized cell growth. PMID:34622919
The structural and functional workings of KEOPS. PMID:34614169
A standard knockout procedure alters expression of adjacent loci at the translational level. PMID:34606617
Systematic High-Content Screening of Fluorescently Tagged Yeast Double Mutant Strains. PMID:34590270
Role of Calcium/Calcineurin Signalling in Regulating Intracellular Reactive Oxygen Species Homeostasis in Saccharomyces cerevisiae. PMID:34573294
A phosphatase-centric mechanism drives stress signaling response. PMID:34558777
A prion accelerates proliferation at the expense of lifespan. PMID:34545808
Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeast. PMID:34544131
ER-SURF: Riding the Endoplasmic Reticulum Surface to Mitochondria. PMID:34502567
Fur4-mediated uracil-scavenging to screen for surface protein regulators. PMID:34498791
Correction: Glutamate dehydrogenase (Gdh2)-dependent alkalization is dispensable for escape from macrophages and virulence of Candida albicans. PMID:34460867
Analysis of local protein accumulation kinetics by live-cell imaging in yeast systems. PMID:34458867
Cdc7-mediated phosphorylation of Cse4 regulates high-fidelity chromosome segregation in budding yeast. PMID:34432494
MRX8, the conserved mitochondrial YihA GTPase family member, is required for de novo Cox1 synthesis at suboptimal temperatures in Saccharomyces cerevisiae. PMID:34432493
Molecular modeling, docking and dynamics analysis of lipid droplet associated enzyme Ypr147cp from Saccharomyces cerevisiae. PMID:34393428
A broadly active fucosyltransferase LmjFUT1 whose mitochondrial localization and activity are essential in parasitic Leishmania. PMID:34385330
Large organellar changes occur during mild heat shock in yeast. PMID:34378783
UbiB proteins regulate cellular CoQ distribution in Saccharomyces cerevisiae. PMID:34362905
Neuroserpin Inclusion Bodies in a FENIB Yeast Model. PMID:34361933
RiboNT: A Noise-Tolerant Predictor of Open Reading Frames from Ribosome-Protected Footprints. PMID:34357073
Puf6 primes 60S pre-ribosome nuclear export at low temperature. PMID:34349113
The C-terminal region of yeast ubiquitin-protein ligase Not4 mediates its cellular localization and stress response. PMID:34338747
Spectrum of Protein Location in Proteomes Captures Evolutionary Relationship Between Species. PMID:34328525
DogCatcher allows loop-friendly protein-protein ligation. PMID:34324879
A CRISPR Interference Screen of Essential Genes Reveals that Proteasome Regulation Dictates Acetic Acid Tolerance in Saccharomyces cerevisiae. PMID:34313457
Topoisomerase II deficiency leads to a postreplicative structural shift in all Saccharomyces cerevisiae chromosomes. PMID:34294749
Proteome plasticity in response to persistent environmental change. PMID:34293321
Nuclear envelope budding is a response to cellular stress. PMID:34290138
Co-culturing experiments reveal the uptake of myo-inositol phosphate synthase (EC 5.5.1.4) in an inositol auxotroph of Saccharomyces cerevisiae. PMID:34281557
Localization, proteomics, and metabolite profiling reveal a putative vesicular transporter for UDP-glucose. PMID:34269178
Protein Subcellular Localization Prediction. PMID:34236663
GFP-fused yeast cells as whole-cell biosensors for genotoxicity evaluation of nitrosamines. PMID:34228183
Genetic Dissection of Vps13 Regulation in Yeast Using Disease Mutations from Human Orthologs. PMID:34201352
A nuclear proteome localization screen reveals the exquisite specificity of Gpn2 in RNA polymerase biogenesis. PMID:34180355
Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. PMID:34166401
Is mRNA decapping by ApaH like phosphatases present in eukaryotes beyond the Kinetoplastida? PMID:34162332
Comparison of endogenously expressed fluorescent protein fusions behaviour for protein quality control and cellular ageing research. PMID:34140587
The ribosome assembly factor Nop53 has a structural role in the formation of nuclear pre-60S intermediates, affecting late maturation events. PMID:34125911
The Impact of Endoplasmic Reticulum-Associated Protein Modifications, Folding and Degradation on Lung Structure and Function. PMID:34122136
The dynein light chain protein Tda2 functions as a dimerization engine to regulate actin capping protein during endocytosis. PMID:34081539
Cell-type-specific, multicolor labeling of endogenous proteins with split fluorescent protein tags in Drosophila. PMID:34074768
Genome Evolutionary Dynamics Meets Functional Genomics: A Case Story on the Identification of SLC25A44. PMID:34073512
Natural variants suppress mutations in hundreds of essential genes. PMID:34042294
Comprehensive characterization of mRNAs associated with yeast cytosolic aminoacyl-tRNA synthetases. PMID:34039240
High-Throughput Imaging of Arrays of Fluorescently Tagged Yeast Mutant Strains. PMID:34028720
Biogenesis of RNA Polymerases in Yeast. PMID:34026841
Defining the role of the polyasparagine repeat domain of the S. cerevisiae transcription factor Azf1p. PMID:34019539
YML018C protein localizes to the vacuolar membrane independently of Atg27p. PMID:33997660
Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase. PMID:33974913
2nSILAC for Quantitative Proteomics of Prototrophic Baker's Yeast. PMID:33950496
A Genome-Wide Screen in Saccharomyces cerevisiae Reveals a Critical Role for Oxidative Phosphorylation in Cellular Tolerance to Lithium Hexafluorophosphate. PMID:33924665
The occurrence order and cross-talk of different tRNA modifications. PMID:33881742
The nucleolus as a polarized coaxial cable in which the rDNA axis is surrounded by dynamic subunit-specific phases. PMID:33862007
Exceptional stability of a perilipin on lipid droplets depends on its polar residues, suggesting multimeric assembly. PMID:33856341
Arf1 directly recruits the Pik1-Frq1 PI4K complex to regulate the final stages of Golgi maturation. PMID:33788598
Modeling DNA trapping of anticancer therapeutic targets using missense mutations identifies dominant synthetic lethal interactions. PMID:33782138
The capacity of origins to load MCM establishes replication timing patterns. PMID:33764973
A nuclear-based quality control pathway for non-imported mitochondrial proteins. PMID:33734083
Human OVCA2 and its homolog FSH3-induced apoptosis in Saccharomyces cerevisiae. PMID:33715035
Protein context shapes the specificity of SH3 domain-mediated interactions in vivo. PMID:33712617
Analysing the yeast complexome-the Complex Portal rising to the challenge. PMID:33677561
A Protocol to Map the Spatial Proteome Using HyperLOPIT in Saccharomyces cerevisiae. PMID:33654815
Comparative parallel analysis of RNA ends identifies mRNA substrates of a tRNA splicing endonuclease-initiated mRNA decay pathway. PMID:33649230
Identifying molecular features that are associated with biological function of intrinsically disordered protein regions. PMID:33616531
Imaging-based screens of pool-synthesized cell libraries. PMID:33589838
Systematic Comparison of Cell Wall-Related Proteins of Different Yeasts. PMID:33572482
Inner-nuclear-membrane-associated degradation employs Dfm1-independent retrotranslocation and alleviates misfolded transmembrane-protein toxicity. PMID:33566711
Toxicity of Single-Walled Carbon Nanotubes (SWCNTs): Effect of Lengths, Functional Groups and Electronic Structures Revealed by a Quantitative Toxicogenomics Assay. PMID:33537148
Expression attenuation as a mechanism of robustness against gene duplication. PMID:33526669
Regulation of COX Assembly and Function by Twin CX9C Proteins-Implications for Human Disease. PMID:33498264
Stress granules display bistable dynamics modulated by Cdk. PMID:33480968
Exploiting the Autozygome to Support Previously Published Mendelian Gene-Disease Associations: An Update. PMID:33456446
Activation of a Mitogen-Activated Protein Kinase Hog1 by DNA Damaging Agent Methyl Methanesulfonate in Yeast. PMID:33425986
Model systems for studying polyphosphate biology: a focus on microorganisms. PMID:33420907
Nutrient transceptors physically interact with the yeast S6/protein kinase B homolog, Sch9, a TOR kinase target. PMID:33394033
The kinetic landscape and interplay of protein networks in cytokinesis. PMID:33392480
Metric Labeling and Semimetric Embedding for Protein Annotation Prediction. PMID:33370163
Multi-parametric characterization of drug effects on cells. PMID:33363713
Autoregulation of yeast ribosomal proteins discovered by efficient search for feedback regulation. PMID:33311538
Pseudouridine-mediated translation control of mRNA by methionine aminoacyl tRNA synthetase. PMID:33305314
DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift. PMID:33288721
Bringing New Methods to the Seed Proteomics Platform: Challenges and Perspectives. PMID:33271881
An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing. PMID:33257684
Biochemical and genetic analysis of Ecm14, a conserved fungal pseudopeptidase. PMID:33256608
The Path towards Predicting Evolution as Illustrated in Yeast Cell Polarity. PMID:33255231
Phenomic screen identifies a role for the yeast lysine acetyltransferase NuA4 in the control of Bcy1 subcellular localization, glycogen biosynthesis, and mitochondrial morphology. PMID:33253187
Cell-cycle phospho-regulation of the kinetochore. PMID:33221975
Pooled protein tagging, cellular imaging, and in situ sequencing for monitoring drug action in real time. PMID:33203764
Simultaneous quantification of mRNA and protein in single cells reveals post-transcriptional effects of genetic variation. PMID:33191917
Unifying the mechanism of mitotic exit control in a spatiotemporal logical model. PMID:33180788
A piggybacking mechanism enables peroxisomal localization of the glyoxylate cycle enzyme Mdh2 in yeast. PMID:33177075
A semi-supervised Bayesian approach for simultaneous protein sub-cellular localisation assignment and novelty detection. PMID:33166281
Protein Homeostasis Networks and the Use of Yeast to Guide Interventions in Alzheimer's Disease. PMID:33126501
Exploring the Complexity of Protein-Level Dosage Compensation that Fine-Tunes Stoichiometry of Multiprotein Complexes. PMID:33112847
Oxidative Stress Responses and Nutrient Starvation in MCHM Treated Saccharomyces cerevisiae. PMID:33109726
A novel assay provides insight into tRNAPhe retrograde nuclear import and re-export in S. cerevisiae. PMID:33074312
Template Stripping Method-Based Au Nanoarray for Surface-Enhanced Raman Scattering Detection of Antiepileptic Drug. PMID:33066672
Nuclear envelope-vacuole contacts mitigate nuclear pore complex assembly stress. PMID:33053148
The Dihydroquinolizinone Compound RG7834 Inhibits the Polyadenylase Function of PAPD5 and PAPD7 and Accelerates the Degradation of Matured Hepatitis B Virus Surface Protein mRNA. PMID:33046485
In vivo mRNA display enables large-scale proteomics by next generation sequencing. PMID:33037152
Paracoccidioides HSP90 Can Be Found in the Cell Surface and Is a Target for Antibodies with Therapeutic Potential. PMID:32998395
Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism. PMID:32978391
Systematic analysis of bypass suppression of essential genes. PMID:32939983
TheCellVision.org: A Database for Visualizing and Mining High-Content Cell Imaging Projects. PMID:32934016
Records of RNA locations in living yeast revealed through covalent marks. PMID:32907940
Transfer RNAs: diversity in form and function. PMID:32900285
tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast. PMID:32893724
Asymmetric Transcription Factor Partitioning During Yeast Cell Division Requires the FACT Chromatin Remodeler and Cell Cycle Progression. PMID:32878900
The Capture of a Disabled Proteasome Identifies Erg25 as a Substrate for Endoplasmic Reticulum Associated Degradation. PMID:32868373
Determining the interaction status and evolutionary fate of duplicated homomeric proteins. PMID:32853212
Tubular ER Associates With Diacylglycerol-Rich Structures During Lipid Droplet Consumption. PMID:32850820
Solid-phase inclusion as a mechanism for regulating unfolded proteins in the mitochondrial matrix. PMID:32821848
Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span. PMID:32821821
Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay. PMID:32817524
Multi-scale 3D Cryo-Correlative Microscopy for Vitrified Cells. PMID:32814034
Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA. PMID:32810142
Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in Chlamydomonas. PMID:32801124
Potassium starvation induces autophagy in yeast. PMID:32788210
Phosphate Homeostasis - A Vital Metabolic Equilibrium Maintained Through the INPHORS Signaling Pathway. PMID:32765429
Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder. PMID:32744794
Complementary α-arrestin-ubiquitin ligase complexes control nutrient transporter endocytosis in response to amino acids. PMID:32744498
A complex genetic interaction implicates that phospholipid asymmetry and phosphate homeostasis regulate Golgi functions. PMID:32730286
Nuclear proteome of virus-infected and healthy potato leaves. PMID:32727361
An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence. PMID:32678853
Impact of Hurricane Maria on Drinking Water Quality in Puerto Rico. PMID:32640159
Harnessing sub-organelle metabolism for biosynthesis of isoprenoids in yeast. PMID:32637671
Origin, conservation, and loss of alternative splicing events that diversify the proteome in Saccharomycotina budding yeasts. PMID:32631843
A septin-Hof1 scaffold at the yeast bud neck binds and organizes actin cables. PMID:32579428
Nucleolar localization of the yeast RNA exosome subunit Rrp44 hints at early pre-rRNA processing as its main function. PMID:32554806
The yeast cell wall protein Pry3 inhibits mating through highly conserved residues within the CAP domain. PMID:32554483
Glucose concentration does not affect degradation of a protein that aberrantly engages the endoplasmic reticulum translocon. PMID:32548573
Crystal structures of Uso1 membrane tether reveal an alternative conformation in the globular head domain. PMID:32533038
Systematic Humanization of the Yeast Cytoskeleton Discerns Functionally Replaceable from Divergent Human Genes. PMID:32522745
Unbiased yeast screens identify cellular pathways affected in Niemann-Pick disease type C. PMID:32487688
Yeast mismatch repair components are required for stable inheritance of gene silencing. PMID:32469861
A new protocol for single-cell RNA-seq reveals stochastic gene expression during lag phase in budding yeast. PMID:32420869
Targeting Signal 3 Extracellularly and Intracellularly in Graft-Versus-Host Disease. PMID:32411139
CRISPR-Cas12a-assisted PCR tagging of mammalian genes. PMID:32406907
Organellar Maps Through Proteomic Profiling - A Conceptual Guide. PMID:32345598
RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia. PMID:32298230
A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination in Saccharomyces cerevisiae. PMID:32265288
Identification and evolutionary analysis of the nucleolar proteome of Giardia lamblia. PMID:32228450
Low costs of adaptation to dietary restriction. PMID:32208792
Comparative analysis of the human serine hydrolase OVCA2 to the model serine hydrolase homolog FSH1 from S. cerevisiae. PMID:32182256
Yeast as a Model to Understand Actin-Mediated Cellular Functions in Mammals-Illustrated with Four Actin Cytoskeleton Proteins. PMID:32164332
CATS: Cas9-assisted tag switching. A high-throughput method for exchanging genomic peptide tags in yeast. PMID:32156257
Systematic genetics and single-cell imaging reveal widespread morphological pleiotropy and cell-to-cell variability. PMID:32064787
WHI-2 Regulates Intercellular Communication via a MAP Kinase Signaling Complex. PMID:32038591
Three members of the yeast N-BAR proteins family form heterogeneous lattices in vivo and interact differentially with two RabGAP proteins. PMID:32015451
High-throughput fluorescence microscopy using multi-frame motion deblurring. PMID:32010517
Spatial Organization of Proteasome Aggregates in the Regulation of Proteasome Homeostasis. PMID:31998748
Cysteine Toxicity Drives Age-Related Mitochondrial Decline by Altering Iron Homeostasis. PMID:31978346
Loss of vacuolar acidity results in iron-sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae. PMID:31975050
Interaction between the yeast RAVE complex and Vph1-containing Vo sectors is a central glucose-sensitive interaction required for V-ATPase reassembly. PMID:31941791
A subcellular proteome atlas of the yeast Komagataella phaffii. PMID:31922548
Mitochondrial localization of Dictyostelium discoideum dUTPase mediated by its N-terminus. PMID:31910901
The genetic basis of aneuploidy tolerance in wild yeast. PMID:31909711
Expanding the CRISPR/Cas9 Toolbox for Gene Engineering in S. cerevisiae. PMID:31901956
Length Specificity and Polymerization Mechanism of (1,3)-β-d-Glucan Synthase in Fungal Cell Wall Biosynthesis. PMID:31899625
TcellSubC: An Atlas of the Subcellular Proteome of Human T Cells. PMID:31849937
The InsP7 phosphatase Siw14 regulates inositol pyrophosphate levels to control localization of the general stress response transcription factor Msn2. PMID:31848224
Development of a yeast model to study the contribution of vacuolar polyphosphate metabolism to lysine polyphosphorylation. PMID:31844018
Clueless forms dynamic, insulin-responsive bliss particles sensitive to stress. PMID:31837288
Effect of cadmium on essential metals and their impact on lipid metabolism in Saccharomyces cerevisiae. PMID:31823289
Siz2 Prevents Ribosomal DNA Recombination by Modulating Levels of Tof2 in Saccharomyces cerevisiae. PMID:31776241
Widespread Prion-Based Control of Growth and Differentiation Strategies in Saccharomyces cerevisiae. PMID:31757756
Resolving noise-control conflict by gene duplication. PMID:31756183
Rab5-mediated endosome formation is regulated at the trans-Golgi network. PMID:31754649
DNA variants affecting the expression of numerous genes in trans have diverse mechanisms of action and evolutionary histories. PMID:31738765
Endoplasmic reticulum stress differentially inhibits endoplasmic reticulum and inner nuclear membrane protein quality control degradation pathways. PMID:31723032
Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast. PMID:31722220
DNA damage checkpoint activation impairs chromatin homeostasis and promotes mitotic catastrophe during aging. PMID:31714209
Hansenula polymorpha Pex37 is a peroxisomal membrane protein required for organelle fission and segregation. PMID:31692262
Phosphorylation of the Gα protein Gpa2 promotes protein kinase A signaling in yeast. PMID:31690628
yRACK1/Asc1 proxiOMICs-Towards Illuminating Ships Passing in the Night. PMID:31689955
The transfer of specific mitochondrial lipids and proteins to lipid droplets contributes to proteostasis upon stress and aging in the eukaryotic model system Saccharomyces cerevisiae. PMID:31676965
Proper secretion of the serpin antithrombin relies strictly on thiol-dependent quality control. PMID:31662433
Estimating numbers of intracellular molecules through analysing fluctuations in photobleaching. PMID:31645577
Yck1 casein kinase I regulates the activity and phosphorylation of Pah1 phosphatidate phosphatase from Saccharomyces cerevisiae. PMID:31645435
Using Yeast to Define the Regulatory Role of Protein Lysine Methylation. PMID:31642774
Fermentation innovation through complex hybridization of wild and domesticated yeasts. PMID:31636426
Experimental evolution reveals a general role for the methyltransferase Hmt1 in noise buffering. PMID:31613873
Histone Chaperone Paralogs Have Redundant, Cooperative, and Divergent Functions in Yeast. PMID:31604797
Mapping the Saccharomyces cerevisiae Spatial Proteome with High Resolution Using hyperLOPIT. PMID:31602611
Unintended perturbation of protein function using GFP nanobodies in human cells. PMID:31601614
Reversible solidification of fission yeast cytoplasm after prolonged nutrient starvation. PMID:31558680
Identifying Protein Complexes from Dynamic Temporal Interval Protein-Protein Interaction Networks. PMID:31531351
Genome architecture and stability in the Saccharomyces cerevisiae knockout collection. PMID:31511699
CDAP: An Online Package for Evaluation of Complex Detection Methods. PMID:31485005
Multicellular group formation in Saccharomyces cerevisiae. PMID:31480977
Learning unsupervised feature representations for single cell microscopy images with paired cell inpainting. PMID:31479439
An electrostatic switching mechanism to control the lipid transfer activity of Osh6p. PMID:31477717
Genetic screen of the yeast environmental stress response dynamics uncovers distinct regulatory phases. PMID:31464369
COSPLAY: An expandable toolbox for combinatorial and swift generation of expression plasmids in yeast. PMID:31461461
The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs. PMID:31454312
The Mutator Phenotype: Adapting Microbial Evolution to Cancer Biology. PMID:31447882
Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation. PMID:31444107
Compartmentalized Synthesis of Triacylglycerol at the Inner Nuclear Membrane Regulates Nuclear Organization. PMID:31422915
The prion-like protein kinase Sky1 is required for efficient stress granule disassembly. PMID:31399582
Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway. PMID:31399514
Remodeling Membrane Binding by Mono-Ubiquitylation. PMID:31370222
High-throughput time-resolved morphology screening in bacteria reveals phenotypic responses to antibiotics. PMID:31341968
Homotypic cooperativity and collective binding are determinants of bHLH specificity and function. PMID:31341088
AraPPINet: An Updated Interactome for the Analysis of Hormone Signaling Crosstalk in Arabidopsis thaliana. PMID:31333706
Functional association of Loc1 and Puf6 with RNA helicase Dhh1 in translational regulation of Saccharomyces cerevisiae Ste12. PMID:31323064
Mutations in the S-Adenosylmethionine Synthetase Genes SAM1 and SAM2 Differentially Affect Genome Stability in Saccharomyces cerevisiae. PMID:31320408
Spatiotemporal dissection of the trans-Golgi network in budding yeast. PMID:31289195
High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding. PMID:31289126
Analysis of novel hyperosmotic shock response suggests 'beads in liquid' cytosol structure. PMID:31285266
Genome-wide functional association networks: background, data & state-of-the-art resources. PMID:31281921
Pooled clone collections by multiplexed CRISPR-Cas12a-assisted gene tagging in yeast. PMID:31273196
Proteome-wide signatures of function in highly diverged intrinsically disordered regions. PMID:31264965
The Role of Transcription Factors and Nuclear Pore Proteins in Controlling the Spatial Organization of the Yeast Genome. PMID:31211995
Novel interconnections of HOG signaling revealed by combined use of two proteomic software packages. PMID:31208443
The structure of the yeast Ctf3 complex. PMID:31194673
Tsr4 Is a Cytoplasmic Chaperone for the Ribosomal Protein Rps2 in Saccharomyces cerevisiae. PMID:31182640
Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector. PMID:31167949
Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics. PMID:31157618
A genetically encoded toolkit of functionalized nanobodies against fluorescent proteins for visualizing and manipulating intracellular signalling. PMID:31122229
Exocyst Subcomplex Functions in Autophagosome Biogenesis by Regulating Atg9 Trafficking. PMID:31103773
mRNA association by aminoacyl tRNA synthetase occurs at a putative anticodon mimic and autoregulates translation in response to tRNA levels. PMID:31100060
The Reduced Level of Inorganic Polyphosphate Mobilizes Antioxidant and Manganese-Resistance Systems in Saccharomyces cerevisiae. PMID:31096715
Synthetic Physical Interactions with the Yeast Centrosome. PMID:31076383
Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME. PMID:31062022
NUDIX hydrolases with inorganic polyphosphate exo- and endopolyphosphatase activities in the glycosome, cytosol and nucleus of Trypanosoma brucei. PMID:31043451
Quantitative analysis of the yeast pheromone pathway. PMID:31022772
The Goldilocks effect of respiration on canavanine tolerance in Saccharomyces cerevisiae. PMID:31011791
Protein Quality Control in the Endoplasmic Reticulum. PMID:31004255
Distinct segregation patterns of yeast cell-peripheral proteins uncovered by a method for protein segregatome analysis. PMID:30975753
Suppression of respiratory growth defect of mitochondrial phosphatidylserine decarboxylase deficient mutant by overproduction of Sfh1, a Sec14 homolog, in yeast. PMID:30958856
iSeq 2.0: A Modular and Interchangeable Toolkit for Interaction Screening in Yeast. PMID:30954477
CellOrganizer: Learning and Using Cell Geometries for Spatial Cell Simulations. PMID:30945250
A fully-automated, robust, and versatile algorithm for long-term budding yeast segmentation and tracking. PMID:30917124
Phosphatidate-mediated regulation of lipid synthesis at the nuclear/endoplasmic reticulum membrane. PMID:30910690
Dissociation rate compensation mechanism for budding yeast pioneer transcription factors. PMID:30888317
Visualization of secretory cargo transport within the Golgi apparatus. PMID:30858192
Increasing throughput of manual microscopy of cell suspensions using solid medium pads. PMID:30847282
tRNA Processing and Subcellular Trafficking Proteins Multitask in Pathways for Other RNAs. PMID:30842788
Environment-dependent fitness gains can be driven by horizontal gene transfer of transporter-encoding genes. PMID:30842288
Minor Isozymes Tailor Yeast Metabolism to Carbon Availability. PMID:30834327
Interaction map of Arabidopsis Mediator complex expounding its topology. PMID:30793213
Improved discovery of genetic interactions using CRISPRiSeq across multiple environments. PMID:30782640
Gcn5 histone acetyltransferase is present in the mitoplasts. PMID:30777878
Prion-dependent proteome remodeling in response to environmental stress is modulated by prion variant and genetic background. PMID:30773982
The structure of the Ctf19c/CCAN from budding yeast. PMID:30762520
Cell cycle-dependent association of polo kinase Cdc5 with CENP-A contributes to faithful chromosome segregation in budding yeast. PMID:30726152
Distribution of Proteins at the Inner Nuclear Membrane Is Regulated by the Asi1 E3 Ligase in Saccharomyces cerevisiae. PMID:30709848
Identification of Suppressor of Clathrin Deficiency-1 (SCD1) and Its Connection to Clathrin-Mediated Endocytosis in Saccharomyces cerevisiae. PMID:30679249
The SEACIT complex is involved in the maintenance of vacuole-mitochondria contact sites and controls mitophagy. PMID:30673821
Saccharomyces cerevisiae ASN1 and ASN2 are asparagine synthetase paralogs that have diverged in their ability to polymerize in response to nutrient stress. PMID:30670751
Genome-Wide Studies of Rho5-Interacting Proteins That Are Involved in Oxidant-Induced Cell Death in Budding Yeast. PMID:30670610
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. PMID:30652105
The adaptor protein Ste50 directly modulates yeast MAPK signaling specificity through differential connections of its RA domain. PMID:30650049
Contribution of Eat1 and Other Alcohol Acyltransferases to Ester Production in Saccharomyces cerevisiae. PMID:30622529
The CRISPR revolution in fungal biology and biotechnology, and beyond. PMID:30598829
Global analysis of protein homomerization in Saccharomyces cerevisiae. PMID:30567710
The intralumenal fragment pathway mediates ESCRT-independent surface transporter down-regulation. PMID:30560896
Cellular landmarks of Trypanosoma brucei and Leishmania mexicana. PMID:30550896
Assessment of GFP Tag Position on Protein Localization and Growth Fitness in Yeast. PMID:30550779
Adaptor protein complex-1 (AP-1) is recruited by the HEATR5 protein Laa1 and its co-factor Laa2 in yeast. PMID:30523155
The subcellular organisation of Saccharomyces cerevisiae. PMID:30503867
Nutritional and meiotic induction of transiently heritable stress resistant states in budding yeast. PMID:30483522
Proteomics of nucleocytoplasmic partitioning. PMID:30472625
A Novel Glycoproteomics Workflow Reveals Dynamic O-GlcNAcylation of COPγ1 as a Candidate Regulator of Protein Trafficking. PMID:30459710
A cell separation checkpoint that enforces the proper order of late cytokinetic events. PMID:30455324
Comparative genomics of nuclear envelope proteins. PMID:30445911
Vacuolar hydrolysis and efflux: current knowledge and unanswered questions. PMID:30422029
Investigation of Ldb19/Art1 localization and function at the late Golgi. PMID:30403748
The pleiotropic effects of the glutamate dehydrogenase (GDH) pathway in Saccharomyces cerevisiae. PMID:30384856
The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1. PMID:30377154
The cellular economy of the Saccharomyces cerevisiae zinc proteome. PMID:30358795
YeastRGB: comparing the abundance and localization of yeast proteins across cells and libraries. PMID:30357397
Determinants of selection in yeast evolved by genome shuffling. PMID:30356826
mCherry-Labeled Verticillium dahliae Could Be Utilized to Investigate Its Pathogenicity Process in Nicotiana benthamiana. PMID:30340423
Understanding molecular mechanisms of disease through spatial proteomics. PMID:30308467
Transfection of choanoflagellates illuminates their cell biology and the ancestry of animal septins. PMID:30281390
Crystal structure and functional analysis of human C1ORF123. PMID:30280012
Pathological alleles of MPV17 modeled in the yeast Saccharomyces cerevisiae orthologous gene SYM1 reveal their inability to take part in a high molecular weight complex. PMID:30273399
The GIS2 Gene Is Repressed by a Zinc-Regulated Bicistronic RNA in Saccharomyces cerevisiae. PMID:30235899
Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast. PMID:30231023
From powerhouse to processing plant: conserved roles of mitochondrial outer membrane proteins in tRNA splicing. PMID:30228203
Model organism data evolving in support of translational medicine. PMID:30224793
High-Reynolds Microfluidic Sorting of Large Yeast Populations. PMID:30214051
A balance of deubiquitinating enzymes controls cell cycle entry. PMID:30207830
Tracking yeast pheromone receptor Ste2 endocytosis using fluorogen-activating protein tagging. PMID:30207829
Layers of regulation of cell-cycle gene expression in the budding yeast Saccharomyces cerevisiae. PMID:30207828
Knockout of the Hmt1p Arginine Methyltransferase in Saccharomyces cerevisiae Leads to the Dysregulation of Phosphate-associated Genes and Processes. PMID:30206180
Super-resolution dipole orientation mapping via polarization demodulation. PMID:30167126
Prediction of Chlamydia pneumoniae protein localization in host mitochondria and cytoplasm and possible involvements in lung cancer etiology: a computational approach. PMID:30166903
Induction of Ptp2 and Cmp2 protein phosphatases is crucial for the adaptive response to ER stress in Saccharomyces cerevisiae. PMID:30166606
Polygenic Analysis in Absence of Major Effector ATF1 Unveils Novel Components in Yeast Flavor Ester Biosynthesis. PMID:30154260
Roles of eIF4E-binding protein Caf20 in Ste12 translation and P-body formation in yeast. PMID:30136257
Brr6 plays a role in gene recruitment and transcriptional regulation at the nuclear envelope. PMID:30133335
Fitness effects of altering gene expression noise in Saccharomyces cerevisiae. PMID:30124429
Analysis of eIF2B bodies and their relationships with stress granules and P-bodies. PMID:30115954
Complete Native Stable Isotope Labeling by Amino Acids of Saccharomyces cerevisiae for Global Proteomic Analysis. PMID:30102515
Identification of a 57S translation complex containing closed-loop factors and the 60S ribosome subunit. PMID:30065356
Transcriptome profiling of whisker follicles in methamphetamine self-administered rats. PMID:30061674
Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners. PMID:30061603
Discoveries of the phosphatidate phosphatase genes in yeast published in the Journal of Biological Chemistry. PMID:30061152
The Lsm1-7/Pat1 complex binds to stress-activated mRNAs and modulates the response to hyperosmotic shock. PMID:30059503
Alcohol Acetyltransferase Eat1 Is Located in Yeast Mitochondria. PMID:30054364
Pareto Optimization of Combinatorial Mutagenesis Libraries. PMID:30040654
Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites. PMID:30018089
Decoding the chromatin proteome of a single genomic locus by DNA sequencing. PMID:30005073
New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue. PMID:29997617
Genome-wide SWAp-Tag yeast libraries for proteome exploration. PMID:29988094
Lateral plasma membrane compartmentalization links protein function and turnover. PMID:29976762
Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population. PMID:29945935
Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins. PMID:29929515
Characterization of a non-nudix pyrophosphatase points to interplay between flavin and NAD(H) homeostasis in Saccharomyces cerevisiae. PMID:29902190
The budding yeast RSC complex maintains ploidy by promoting spindle pole body insertion. PMID:29875260
Penetrating cations induce pleiotropic drug resistance in yeast. PMID:29802261
Distributed and dynamic intracellular organization of extracellular information. PMID:29784812
Transgenic Mice Carrying GLUD2 as a Tool for Studying the Expressional and the Functional Adaptation of this Positive Selected Gene in Human Brain Evolution. PMID:29777493
Altered sterol metabolism in budding yeast affects mitochondrial iron-sulfur (Fe-S) cluster synthesis. PMID:29773647
The new normal of structure/function studies in the era of CRISPR/Cas9. PMID:29764955
Negative Regulation Gene Circuits for Efflux Pump Control. PMID:29754221
Network inference reveals novel connections in pathways regulating growth and defense in the yeast salt response. PMID:29738528
To Decipher the Mycoplasma hominis Proteins Targeting into the Endoplasmic Reticulum and Their Implications in Prostate Cancer Etiology Using Next-Generation Sequencing Data. PMID:29695086
YAAM: Yeast Amino Acid Modifications Database. PMID:29688347
Extramitochondrial Assembly of Mitochondrial Targeting Signal Disrupted Mitochondrial Enzyme Aldehyde Dehydrogenase. PMID:29670139
Genotoxicity Assessment of Drinking Water Disinfection Byproducts by DNA Damage and Repair Pathway Profiling Analysis. PMID:29660283
MitoCPR-A surveillance pathway that protects mitochondria in response to protein import stress. PMID:29650645
Integrating images from multiple microscopy screens reveals diverse patterns of change in the subcellular localization of proteins. PMID:29620521
Localizing Antifungal Drugs to the Correct Organelle Can Markedly Enhance their Efficacy. PMID:29575397
Database for High Throughput Screening Hits (dHITS): a simple tool to retrieve gene specific phenotypes from systematic screens done in yeast. PMID:29574976
Toolbox: Creating a systematic database of secretory pathway proteins uncovers new cargo for COPI. PMID:29527758
Reactive oxygen species stress increases accumulation of tyrosyl-DNA phsosphodiesterase 1 within mitochondria. PMID:29523818
A newly characterized vacuolar serine carboxypeptidase, Atg42/Ybr139w, is required for normal vacuole function and the terminal steps of autophagy in the yeast Saccharomyces cerevisiae. PMID:29514932
Turnover of aberrant pre-40S pre-ribosomal particles is initiated by a novel endonucleolytic decay pathway. PMID:29481617
The Yeast Saccharomyces cerevisiae as a Model for Understanding RAS Proteins and their Role in Human Tumorigenesis. PMID:29463063
Regulation of the Stress-Activated Degradation of Mitochondrial Respiratory Complexes in Yeast. PMID:29441058
Brr6 and Brl1 locate to nuclear pore complex assembly sites to promote their biogenesis. PMID:29439116
Heat shock transcriptional factor mediates mitochondrial unfolded protein response. PMID:29423676
Fat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes. PMID:29417057
Homocysteine regulates fatty acid and lipid metabolism in yeast. PMID:29414770
A Novel Assay Reveals a Maturation Process during Ascospore Wall Formation. PMID:29371570
Large-scale aggregation analysis of eukaryotic proteins reveals an involvement of intrinsically disordered regions in protein folding. PMID:29330519
The endosomal trafficking factors CORVET and ESCRT suppress plasma membrane residence of the renal outer medullary potassium channel (ROMK). PMID:29311259
RAD4 and RAD23/HMR Contribute to Arabidopsis UV Tolerance. PMID:29283431
Heat stress promotes longevity in budding yeast by relaxing the confinement of age-promoting factors in the mother cell. PMID:29283340
The role of phospholipid molecular species in determining the physical properties of yeast membranes. PMID:29265372
Oxidative stress triggers aggregation of GFP-tagged Hsp31p, the budding yeast environmental stress response chaperone, and glyoxalase III. PMID:29264711
Yeast Still a Beast: Diverse Applications of CRISPR/Cas Editing Technology in S. cerevisiae. PMID:29259528
Protein Subcellular Localization with Gaussian Kernel Discriminant Analysis and Its Kernel Parameter Selection. PMID:29244758
A new method for post-translationally labeling proteins in live cells for fluorescence imaging and tracking. PMID:29228311
The Na+(K+)/H+ exchanger Nhx1 controls multivesicular body-vacuolar lysosome fusion. PMID:29212874
The Promise of Systems Biology Approaches for Revealing Host Pathogen Interactions in Malaria. PMID:29201016
Stress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagy. PMID:29198169
Ribosome biogenesis in cancer: new players and therapeutic avenues. PMID:29192214
tRNA dynamics between the nucleus, cytoplasm and mitochondrial surface: Location, location, location. PMID:29191733
Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation. PMID:29187527
Preparation and Characterization of Enzyme Compartments in UV-Cured Polyurethane-Based Materials and Their Application in Enzymatic Reactions. PMID:29170654
Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway. PMID:29161034
Spatial cues and not spindle pole maturation drive the asymmetry of astral microtubules between new and preexisting spindle poles. PMID:29142076
Defining the protein complexome of translation termination factor eRF1: Identification of four novel eRF1-containing complexes that range from 20S to 57S in size. PMID:29139201
Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family. PMID:29126261
Autophagic clearance of proteasomes in yeast requires the conserved sorting nexin Snx4. PMID:29109144
Metals in fungal virulence. PMID:29069482
Characterization of the subcellular localization of Epstein-Barr virus encoded proteins in live cells. PMID:29050259
The role of PKA in the translational response to heat stress in Saccharomyces cerevisiae. PMID:29045428
Behead and live long or the tale of cathepsin L. PMID:29044689
The contribution of Saccharomyces cerevisiae replicative age to the variations in the levels of Trx2p, Pdr5p, Can1p and Idh isoforms. PMID:29038504
Capturing the Asc1p/Receptor for Activated C Kinase 1 (RACK1) Microenvironment at the Head Region of the 40S Ribosome with Quantitative BioID in Yeast. PMID:28982715
A Comprehensive Analysis of Transcript-Supported De Novo Genes in Saccharomyces sensu stricto Yeasts. PMID:28981695
CRISPR-UnLOCK: Multipurpose Cas9-Based Strategies for Conversion of Yeast Libraries and Strains. PMID:28979241
Selective aggregation of the splicing factor Hsh155 suppresses splicing upon genotoxic stress. PMID:28978642
Zap1-dependent transcription from an alternative upstream promoter controls translation of RTC4 mRNA in zinc-deficient Saccharomyces cerevisiae. PMID:28963784
Screening of potential genes contributing to the macrocycle drug resistance of C. albicans via microarray analysis. PMID:28944888
Two NAD-linked redox shuttles maintain the peroxisomal redox balance in Saccharomyces cerevisiae. PMID:28928432
Exacerbating and reversing lysosomal storage diseases: from yeast to humans. PMID:28913343
Retrograde nuclear transport from the cytoplasm is required for tRNATyr maturation in T. brucei. PMID:28901827
The ATPase Fap7 Tests the Ability to Carry Out Translocation-like Conformational Changes and Releases Dim1 during 40S Ribosome Maturation. PMID:28890337
Yeast silencing factor Sir4 and a subset of nucleoporins form a complex distinct from nuclear pore complexes. PMID:28883038
Vps13-Mcp1 interact at vacuole-mitochondria interfaces and bypass ER-mitochondria contact sites. PMID:28864540
Development of a comprehensive set of tools for genome engineering in a cold- and thermo-tolerant Kluyveromyces marxianus yeast strain. PMID:28827530
Phosphatidate phosphatase regulates membrane phospholipid synthesis via phosphatidylserine synthase. PMID:28827025
Subcellular Localization of a Plant Catalase-Phenol Oxidase, AcCATPO, from Amaranthus and Identification of a Non-canonical Peroxisome Targeting Signal. PMID:28824680
Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization. PMID:28814507
Splicing and transcription touch base: co-transcriptional spliceosome assembly and function. PMID:28792005
Ubiquitin orchestrates proteasome dynamics between proliferation and quiescence in yeast. PMID:28768827
Architecture and dynamics of overlapped RNA regulatory networks. PMID:28768715
Microtubule-dependent ribosome localization in C. elegans neurons. PMID:28767038
Functional annotation of chemical libraries across diverse biological processes. PMID:28759014
Ribonucleoprotein purification and characterization using RNA Mango. PMID:28747322
Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress. PMID:28746874
Two novel effectors of trafficking and maturation of the yeast plasma membrane H+ -ATPase. PMID:28727280
Direct interaction of the Golgi V-ATPase a-subunit isoform with PI(4)P drives localization of Golgi V-ATPases in yeast. PMID:28720663
Syp1 regulates the clathrin-mediated and clathrin-independent endocytosis of multiple cargo proteins through a novel sorting motif. PMID:28701344
A simple microfluidic platform to study age-dependent protein abundance and localization changes in Saccharomyces cerevisiae. PMID:28685142
MNRR1, a Biorganellar Regulator of Mitochondria. PMID:28685009
Yeast PAH1-encoded phosphatidate phosphatase controls the expression of CHO1-encoded phosphatidylserine synthase for membrane phospholipid synthesis. PMID:28673963
The effects of glutamine/asparagine content on aggregation and heterologous prion induction by yeast prion-like domains. PMID:28665753
Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale. PMID:28658629
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response. PMID:28648781
The Fungal Pathogen Candida glabrata Does Not Depend on Surface Ferric Reductases for Iron Acquisition. PMID:28642757
Epigenetic Transcriptional Memory of GAL Genes Depends on Growth in Glucose and the Tup1 Transcription Factor in Saccharomyces cerevisiae. PMID:28607146
The Evolution of Substrate Specificity by tRNA Modification Enzymes. PMID:28601226
Saccharomyces cerevisiae cells lacking Pex3 contain membrane vesicles that harbor a subset of peroxisomal membrane proteins. PMID:28552664
The Incomplete Glutathione Puzzle: Just Guessing at Numbers and Figures? PMID:28540740
Yeast ENV9 encodes a conserved lipid droplet (LD) short-chain dehydrogenase involved in LD morphology. PMID:28540421
Systematic comparison of 2A peptides for cloning multi-genes in a polycistronic vector. PMID:28526819
In vivo mapping of tissue- and subcellular-specific proteomes in Caenorhabditis elegans. PMID:28508060
Heterosis as a consequence of regulatory incompatibility. PMID:28494792
Phenotypic heterogeneity promotes adaptive evolution. PMID:28486496
Real-Time Imaging of the Azole Class of Antifungal Drugs in Live Candida Cells. PMID:28472585
A method for labeling proteins with tags at the native genomic loci in budding yeast. PMID:28459859
The Nucleoporin Nup2 Contains a Meiotic-Autonomous Region that Promotes the Dynamic Chromosome Events of Meiosis. PMID:28455351
Automated analysis of high-content microscopy data with deep learning. PMID:28420678
Nonlinear feedback drives homeostatic plasticity in H2O2 stress response. PMID:28418333
Peroxisome Mini-Libraries: Systematic Approaches to Study Peroxisomes Made Easy. PMID:28409473
Accurate Classification of Protein Subcellular Localization from High-Throughput Microscopy Images Using Deep Learning. PMID:28391243
Differentiated cytoplasmic granule formation in quiescent and non-quiescent cells upon chronological aging. PMID:28357341
From the baker to the bedside: yeast models of Parkinson's disease. PMID:28357302
Amino acid substitution equivalent to human chorea-acanthocytosis I2771R in yeast Vps13 protein affects its binding to phosphatidylinositol 3-phosphate. PMID:28334785
TheCellMap.org: A Web-Accessible Database for Visualizing and Mining the Global Yeast Genetic Interaction Network. PMID:28325812
Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs. PMID:28298493
Requirement of a Functional Flavin Mononucleotide Prenyltransferase for the Activity of a Bacterial Decarboxylase in a Heterologous Muconic Acid Pathway in Saccharomyces cerevisiae. PMID:28283523
Identifying protein kinase-specific effectors of the osmostress response in yeast. PMID:28270554
Conserved forkhead dimerization motif controls DNA replication timing and spatial organization of chromosomes in S. cerevisiae. PMID:28265091
Cytosolic proteostasis through importing of misfolded proteins into mitochondria. PMID:28241148
Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae. PMID:28231279
A global characterization of the translational and transcriptional programs induced by methionine restriction through ribosome profiling and RNA-seq. PMID:28212626
Identification of Genes in Saccharomyces cerevisiae that Are Haploinsufficient for Overcoming Amino Acid Starvation. PMID:28209762
The Subcellular Localisation of Neuronal Nitric Oxide Synthase Determines the Downstream Effects of NO on Myocardial Function. PMID:28158509
A pathway of targeted autophagy is induced by DNA damage in budding yeast. PMID:28154131
Functional Analysis of Kinases and Transcription Factors in Saccharomyces cerevisiae Using an Integrated Overexpression Library. PMID:28122947
Budding Yeast: An Ideal Backdrop for In vivo Lipid Biochemistry. PMID:28119915
Crosstalk between the nucleolus and the DNA damage response. PMID:28112326
The roles of RRP15 in nucleolar formation, ribosome biogenesis and checkpoint control in human cells. PMID:28099941
A targeted RNAi screen identifies factors affecting diverse stages of receptor-mediated transcytosis. PMID:28069747
A molecular genetic toolbox for Yarrowia lipolytica. PMID:28066508
Pex35 is a regulator of peroxisome abundance. PMID:28049721
Disruption of Protein Mannosylation Affects Candida guilliermondii Cell Wall, Immune Sensing, and Virulence. PMID:27994582
Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation. PMID:27976729
A Stochastic Model of the Yeast Cell Cycle Reveals Roles for Feedback Regulation in Limiting Cellular Variability. PMID:27935947
Slm35 links mitochondrial stress response and longevity through TOR signaling pathway. PMID:27922823
The yeast 14-3-3 proteins BMH1 and BMH2 differentially regulate rapamycin-mediated transcription. PMID:27919033
The Natural Variation in Lifespans of Single Yeast Cells Is Related to Variation in Cell Size, Ribosomal Protein, and Division Time. PMID:27907085
The SND proteins constitute an alternative targeting route to the endoplasmic reticulum. PMID:27905431
Dominant Epistasis Between Two Quantitative Trait Loci Governing Sporulation Efficiency in Yeast Saccharomyces cerevisiae. PMID:27904371
Genetic selection for mistranslation rescues a defective co-chaperone in yeast. PMID:27899648
Calcium channel regulator Mid1 links TORC2-mediated changes in mitochondrial respiration to autophagy. PMID:27899413
How and why intralumenal membrane fragments form during vacuolar lysosome fusion. PMID:27881666
Regulation of EGFR surface levels by COPII-dependent trafficking. PMID:27872251
Mitochondrial Superoxide Dismutase and Yap1p Act as a Signaling Module Contributing to Ethanol Tolerance of the Yeast Saccharomyces cerevisiae. PMID:27864171
Prediction of interacting proteins from homology-modeled complex structures using sequence and structure scores. PMID:27857563
Analysis of membrane proteins localizing to the inner nuclear envelope in living cells. PMID:27831485
Saccharomyces cerevisiae single-copy plasmids for auxotrophy compensation, multiple marker selection, and for designing metabolically cooperating communities. PMID:27830062
Exploring genetic suppression interactions on a global scale. PMID:27811238
Inappropriate expression of the translation elongation factor 1A disrupts genome stability and metabolism. PMID:27807005
GOLGI TRANSPORT 1B Regulates Protein Export from the Endoplasmic Reticulum in Rice Endosperm Cells. PMID:27803308
Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway. PMID:27791147
Expression of varied GFPs in Saccharomyces cerevisiae: codon optimization yields stronger than expected expression and fluorescence intensity. PMID:27782154
Neo1 and phosphatidylethanolamine contribute to vacuole membrane fusion in Saccharomyces cerevisiae. PMID:27738552
Scarless Gene Tagging with One-Step Transformation and Two-Step Selection in Saccharomyces cerevisiae and Schizosaccharomyces pombe. PMID:27736907
A global genetic interaction network maps a wiring diagram of cellular function. PMID:27708008
Deubiquitinase activity is required for the proteasomal degradation of misfolded cytosolic proteins upon heat-stress. PMID:27698423
Determining the Mitochondrial Methyl Proteome in Saccharomyces cerevisiae using Heavy Methyl SILAC. PMID:27696855
Characterization of proteome dynamics during growth in oleate reveals a new peroxisome-targeting receptor. PMID:27663510
Dual regulation of cytoplasmic and mitochondrial acetyl-CoA utilization for improved isoprene production in Saccharomyces cerevisiae. PMID:27650330
New families of single integration vectors and gene tagging plasmids for genetic manipulations in budding yeast. PMID:27637489
Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci. PMID:27617677
Arginine methylation promotes translation repression activity of eIF4G-binding protein, Scd6. PMID:27613419
Predictive biophysical modeling and understanding of the dynamics of mRNA translation and its evolution. PMID:27591251
A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins. PMID:27552055
Patterning protein complexes on DNA nanostructures using a GFP nanobody. PMID:27538185
Predicting diabetes mellitus genes via protein-protein interaction and protein subcellular localization information. PMID:27535125
Lipid synthesis and membrane contact sites: a crossroads for cellular physiology. PMID:27521373
Ribonucleotides and Transcription-Associated Mutagenesis in Yeast. PMID:27511624
Cotranslational signal-independent SRP preloading during membrane targeting. PMID:27487213
An Unsupervised kNN Method to Systematically Detect Changes in Protein Localization in High-Throughput Microscopy Images. PMID:27442431
ER arrival sites for COPI vesicles localize to hotspots of membrane trafficking. PMID:27440402
Constitutive turnover of histone H2A.Z at yeast promoters requires the preinitiation complex. PMID:27438412
Sar1 localizes at the rims of COPII-coated membranes in vivo. PMID:27432890
New insights into decapping enzymes and selective mRNA decay. PMID:27425147
Altered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus. PMID:27385342
Ribosomal proteins produced in excess are degraded by the ubiquitin-proteasome system. PMID:27385339
Detection of protein-protein interactions at the septin collar in Saccharomyces cerevisiae using a tripartite split-GFP system. PMID:27385335
Regulation of the Na+/K+-ATPase Ena1 Expression by Calcineurin/Crz1 under High pH Stress: A Quantitative Study. PMID:27362362
Resonance Raman Probes for Organelle-Specific Labeling in Live Cells. PMID:27339882
Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice. PMID:27329800
Human Protein Subcellular Localization with Integrated Source and Multi-label Ensemble Classifier. PMID:27323846
A family of metal-dependent phosphatases implicated in metabolite damage-control. PMID:27322068
Filamentation of Metabolic Enzymes in Saccharomyces cerevisiae. PMID:27312010
Classifying and segmenting microscopy images with deep multiple instance learning. PMID:27307644
Protein Abundance Control by Non-coding Antisense Transcription. PMID:27292640
Multiple-Localization and Hub Proteins. PMID:27285823
Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites. PMID:27280386
Global, quantitative and dynamic mapping of protein subcellular localization. PMID:27278775
Data on dynamic study of cytoophidia in Saccharomyces cerevisiae. PMID:27274529
A scalable strategy for high-throughput GFP tagging of endogenous human proteins. PMID:27274053
Defects in THO/TREX-2 function cause accumulation of novel cytoplasmic mRNP granules that can be cleared by autophagy. PMID:27251550
The Essential Neo1 Protein from Budding Yeast Plays a Role in Establishing Aminophospholipid Asymmetry of the Plasma Membrane. PMID:27235400
CRISPR-directed mitotic recombination enables genetic mapping without crosses. PMID:27230379
Mcp3 is a novel mitochondrial outer membrane protein that follows a unique IMP-dependent biogenesis pathway. PMID:27226123
Membrane-association of mRNA decapping factors is independent of stress in budding yeast. PMID:27146487
Requirements for Carnitine Shuttle-Mediated Translocation of Mitochondrial Acetyl Moieties to the Yeast Cytosol. PMID:27143389
Peroxins Pex30 and Pex29 Dynamically Associate with Reticulons to Regulate Peroxisome Biogenesis from the Endoplasmic Reticulum. PMID:27129769
Efflux Pump Control Alters Synthetic Gene Circuit Function. PMID:27111147
Synthetic protein interactions reveal a functional map of the cell. PMID:27098839
Selective sorting and destruction of mitochondrial membrane proteins in aged yeast. PMID:27097106
Rad7 E3 Ubiquitin Ligase Attenuates Polyubiquitylation of Rpn10 and Dsk2 Following DNA Damage in Saccharomyces cerevisiae. PMID:27092291
Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans. PMID:27084949
Tracking Diacylglycerol and Phosphatidic Acid Pools in Budding Yeast. PMID:27081314
The Evolving Contribution of Mass Spectrometry to Integrative Structural Biology. PMID:27056566
Imaging of Endogenous Metabolites of Plant Leaves by Mass Spectrometry Based on Laser Activated Electron Tunneling. PMID:27053227
The Proteasome Subunit Rpn8 Interacts with the Small Nucleolar RNA Protein (snoRNP) Assembly Protein Pih1 and Mediates Its Ubiquitin-independent Degradation in Saccharomyces cerevisiae. PMID:27053109
Overexpression of Sly41 suppresses COPII vesicle-tethering deficiencies by elevating intracellular calcium levels. PMID:27030673
Eisosomes promote the ability of Sur7 to regulate plasma membrane organization in Candida albicans. PMID:27009204
A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy. PMID:27003292
Versatile protein tagging in cells with split fluorescent protein. PMID:26988139
Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance. PMID:26966248
Systematic Analysis of Yeast Proteome Reveals Peptide Detectability Factors for Mass Spectrometry. PMID:26962293
Stoichiometry and Change of the mRNA Closed-Loop Factors as Translating Ribosomes Transit from Initiation to Elongation. PMID:26953568
Hsp90 Maintains Proteostasis of the Galactose Utilization Pathway To Prevent Cell Lethality. PMID:26951197
Functions for diverse metabolic activities in heterochromatin. PMID:26936955
Failure of RQC machinery causes protein aggregation and proteotoxic stress. PMID:26934223
One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. PMID:26928762
MTE1 Functions with MPH1 in Double-Strand Break Repair. PMID:26920759
Yeast as a Heterologous Model System to Uncover Type III Effector Function. PMID:26914889
Regulation of Golgi Cisternal Progression by Ypt/Rab GTPases. PMID:26906739
Characterization of Three New Glutaredoxin Genes in the Arbuscular Mycorrhizal Fungus Rhizophagus irregularis: Putative Role of RiGRX4 and RiGRX5 in Iron Homeostasis. PMID:26900849
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling. PMID:26898226
Alternative reactions at the interface of glycolysis and citric acid cycle in Saccharomyces cerevisiae. PMID:26895788
Dynamics of CDKN1A in Single Cells Defined by an Endogenous Fluorescent Tagging Toolkit. PMID:26876176
Computational prediction of Mycoplasma hominis proteins targeting in nucleus of host cell and their implication in prostate cancer etiology. PMID:26874727
Identification of Cell Cycle Dependent Interaction Partners of the Septins by Quantitative Mass Spectrometry. PMID:26871441
Water-Transfer Slows Aging in Saccharomyces cerevisiae. PMID:26862897
Improvement of Mitochondria Extract from Saccharomyces cerevisiae Characterization in Shotgun Proteomics Using Sheathless Capillary Electrophoresis Coupled to Tandem Mass Spectrometry. PMID:26860395
A Quantitative Toxicogenomics Assay for High-throughput and Mechanistic Genotoxicity Assessment and Screening of Environmental Pollutants. PMID:26855253
Unbiased Rare Event Sampling in Spatial Stochastic Systems Biology Models Using a Weighted Ensemble of Trajectories. PMID:26845334
Improved Acetic Acid Resistance in Saccharomyces cerevisiae by Overexpression of the WHI2 Gene Identified through Inverse Metabolic Engineering. PMID:26826231
Ty1 Integrase Interacts with RNA Polymerase III-specific Subcomplexes to Promote Insertion of Ty1 Elements Upstream of Polymerase (Pol) III-transcribed Genes. PMID:26797132
Programmable polyproteams built using twin peptide superglues. PMID:26787909
PP1-Dependent Formin Bnr1 Dephosphorylation and Delocalization from a Cell Division Site. PMID:26771880
Vesicular Trafficking Systems Impact TORC1-Controlled Transcriptional Programs in Saccharomyces cerevisiae. PMID:26739646
Scope and limitations of yeast as a model organism for studying human tissue-specific pathways. PMID:26714768
Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly. PMID:26711263
HitPredict version 4: comprehensive reliability scoring of physical protein-protein interactions from more than 100 species. PMID:26708988
N-Glycan-based ER Molecular Chaperone and Protein Quality Control System: The Calnexin Binding Cycle. PMID:26676362
Starvation Induces Proteasome Autophagy with Different Pathways for Core and Regulatory Particles. PMID:26670610
The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components. PMID:26666917
Understanding the regulation of coding and noncoding transcription in cell populations. PMID:26660659
Analysis of COPII Vesicles Indicates a Role for the Emp47-Ssp120 Complex in Transport of Cell Surface Glycoproteins. PMID:26650540
Genome-wide Screen of Pseudomonas aeruginosa in Saccharomyces cerevisiae Identifies New Virulence Factors. PMID:26636043
Conserved mRNA-binding proteomes in eukaryotic organisms. PMID:26595419
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei. PMID:26577437
Yeast Interspecies Comparative Proteomics Reveals Divergence in Expression Profiles and Provides Insights into Proteome Resource Allocation and Evolutionary Roles of Gene Duplication. PMID:26560065
Single-cell phenomics in budding yeast. PMID:26543200
Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins. PMID:26527740
Protein-RNA networks revealed through covalent RNA marks. PMID:26524240
The current state of eukaryotic DNA base damage and repair. PMID:26519467
A set of GFP-based organelle marker lines combined with DsRed-based gateway vectors for subcellular localization study in rice (Oryza sativa L.). PMID:26519260
An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis. PMID:26516084
Building a KATalogue of acetyllysine targeting and function. PMID:26512033
The systematic analysis of protein-lipid interactions comes of age. PMID:26507169
Protein acetylation in metabolism - metabolites and cofactors. PMID:26503676
Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p. PMID:26493364
Cell biology of the future: Nanometer-scale cellular cartography. PMID:26483557
Epitope-tagged yeast strains reveal promoter driven changes to 3'-end formation and convergent antisense-transcription from common 3' UTRs. PMID:26481348
Target of rapamycin signaling mediates vacuolar fission caused by endoplasmic reticulum stress in Saccharomyces cerevisiae. PMID:26466677
Condition-specific genetic interaction maps reveal crosstalk between the cAMP/PKA and the HOG MAPK pathways in the activation of the general stress response. PMID:26446933
A strategy for dissecting the architectures of native macromolecular assemblies. PMID:26436480
Proteome-wide quantitative multiplexed profiling of protein expression: carbon-source dependency in Saccharomyces cerevisiae. PMID:26399295
Yeast GSK-3 kinase regulates astral microtubule function through phosphorylation of the microtubule-stabilizing kinesin Kip2. PMID:26395399
Proteomic Analysis of Dhh1 Complexes Reveals a Role for Hsp40 Chaperone Ydj1 in Yeast P-Body Assembly. PMID:26392412
Conserved function of the lysine-based KXD/E motif in Golgi retention for endomembrane proteins among different organisms. PMID:26378254
Per-Arnt-Sim Kinase (PASK): An Emerging Regulator of Mammalian Glucose and Lipid Metabolism. PMID:26371032
ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13. PMID:26370498
New Regulators of Clathrin-Mediated Endocytosis Identified in Saccharomyces cerevisiae by Systematic Quantitative Fluorescence Microscopy. PMID:26362318
Systematic analysis of asymmetric partitioning of yeast proteome between mother and daughter cells reveals "aging factors" and mechanism of lifespan asymmetry. PMID:26351681
The Stationary-Phase Cells of Saccharomyces cerevisiae Display Dynamic Actin Filaments Required for Processes Extending Chronological Life Span. PMID:26351139
ProSim: A Method for Prioritizing Disease Genes Based on Protein Proximity and Disease Similarity. PMID:26339594
Polyglutamine toxicity in yeast induces metabolic alterations and mitochondrial defects. PMID:26335097
Fluorescent foci quantitation for high-throughput analysis. PMID:26290880
Cellobionic acid utilization: from Neurospora crassa to Saccharomyces cerevisiae. PMID:26279678
The Evolutionary Potential of Phenotypic Mutations. PMID:26244544
Synthetic physical interactions map kinetochore regulators and regions sensitive to constitutive Cdc14 localization. PMID:26240346
Sequestration of mRNAs Modulates the Timing of Translation during Meiosis in Budding Yeast. PMID:26217015
Tunable and reversible drug control of protein production via a self-excising degron. PMID:26214256
Sortin2 enhances endocytic trafficking towards the vacuole in Saccharomyces cerevisiae. PMID:26209329
Candida glabrata: new tools and technologies-expanding the toolkit. PMID:26205243
Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120. PMID:26196125
The Gcn2 Regulator Yih1 Interacts with the Cyclin Dependent Kinase Cdc28 and Promotes Cell Cycle Progression through G2/M in Budding Yeast. PMID:26176233
An Updated Collection of Sequence Barcoded Temperature-Sensitive Alleles of Yeast Essential Genes. PMID:26175450
High-throughput analysis of yeast replicative aging using a microfluidic system. PMID:26170317
Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p. PMID:26158509
High-throughput microfluidics to control and measure signaling dynamics in single yeast cells. PMID:26158443
Green to red photoconversion of GFP for protein tracking in vivo. PMID:26148899
SUB1 Plays a Negative Role during Starvation Induced Sporulation Program in Saccharomyces cerevisiae. PMID:26147804
Mediator tail subunits can form amyloid-like aggregates in vivo and affect stress response in yeast. PMID:26138482
Rechecking the Centrality-Lethality Rule in the Scope of Protein Subcellular Localization Interaction Networks. PMID:26115027
Inferring orthologous gene regulatory networks using interspecies data fusion. PMID:26072515
Beyond Agar: Gel Substrates with Improved Optical Clarity and Drug Efficiency and Reduced Autofluorescence for Microbial Growth Experiments. PMID:26070672
Optimized sample preparation for single-molecule localization-based superresolution microscopy in yeast. PMID:26068895
CYCLoPs: A Comprehensive Database Constructed from Automated Analysis of Protein Abundance and Subcellular Localization Patterns in Saccharomyces cerevisiae. PMID:26048563
Nuclear pore complex integrity requires Lnp1, a regulator of cortical endoplasmic reticulum. PMID:26041935
Structural evidence for Scc4-dependent localization of cohesin loading. PMID:26038942
Probing Yeast Polarity with Acute, Reversible, Optogenetic Inhibition of Protein Function. PMID:26035630
The Monoterpene Carvacrol Generates Endoplasmic Reticulum Stress in the Pathogenic Fungus Candida albicans. PMID:26014932
Control of relative timing and stoichiometry by a master regulator. PMID:26000862
Metallothionein as a clonable tag for protein localization by electron microscopy of cells. PMID:25974385
The Carboxy-Terminal Tails of Septins Cdc11 and Shs1 Recruit Myosin-II Binding Factor Bni5 to the Bud Neck in Saccharomyces cerevisiae. PMID:25971666
Live imaging of endogenous protein dynamics in zebrafish using chromobodies. PMID:25968318
The ArfGAP2/3 Glo3 and ergosterol collaborate in transport of a subset of cargoes. PMID:25964658
Toxicity Assessment of 4-Methyl-1-cyclohexanemethanol and Its Metabolites in Response to a Recent Chemical Spill in West Virginia, USA. PMID:25961958
Degradation of Ndd1 by APC/C(Cdh1) generates a feed forward loop that times mitotic protein accumulation. PMID:25959309
Feedback Control of Snf1 Protein and Its Phosphorylation Is Necessary for Adaptation to Environmental Stress. PMID:25947383
A family of tetraspans organizes cargo for sorting into multivesicular bodies. PMID:25942624
The Aspergillus fumigatus sitA Phosphatase Homologue Is Important for Adhesion, Cell Wall Integrity, Biofilm Formation, and Virulence. PMID:25911225
A Double-Barrel Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) System to Quantify 96 Interactomes per Day. PMID:25887394
An approach for determining and measuring network hierarchy applied to comparing the phosphorylome and the regulome. PMID:25880651
Overexpression of PAD1 and FDC1 results in significant cinnamic acid decarboxylase activity in Saccharomyces cerevisiae. PMID:25852989
Systematic identification of signal integration by protein kinase A. PMID:25831502
Probing the closed-loop model of mRNA translation in living cells. PMID:25826658
Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. PMID:25817432
Solution structure of the Atg1 complex: implications for the architecture of the phagophore assembly site. PMID:25817386
Evolutionarily conserved 5'-3' exoribonuclease Xrn1 accumulates at plasma membrane-associated eisosomes in post-diauxic yeast. PMID:25811606
The fascinating and secret wild life of the budding yeast S. cerevisiae. PMID:25807086
Flow Cytometry: Impact on Early Drug Discovery. PMID:25805180
Ypt1 and TRAPP interactions: optimization of multicolor bimolecular fluorescence complementation in yeast. PMID:25800836
Quantifying nucleoporin stoichiometry inside single nuclear pore complexes in vivo. PMID:25797490
Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth. PMID:25778921
Altering nuclear pore complex function impacts longevity and mitochondrial function in S. cerevisiae. PMID:25778920
Genome-Wide Localization Study of Yeast Pex11 Identifies Peroxisome-Mitochondria Interactions through the ERMES Complex. PMID:25769804
A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways. PMID:25759509
Affinity proteomics to study endogenous protein complexes: pointers, pitfalls, preferences and perspectives. PMID:25757543
The ribosome-associated complex antagonizes prion formation in yeast. PMID:25739058
Cell biology of mitotic recombination. PMID:25731763
Puromycin- and methotrexate-resistance cassettes and optimized Cre-recombinase expression plasmids for use in yeast. PMID:25688547
MiRNA mimic screen for improved expression of functional neurotensin receptor from HEK293 cells. PMID:25676429
Cytosolic chaperones mediate quality control of higher-order septin assembly in budding yeast. PMID:25673805
Actin and endocytosis in budding yeast. PMID:25657349
A conserved domain important for association of eukaryotic J-protein co-chaperones Jjj1 and Zuo1 with the ribosome. PMID:25639645
Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan. PMID:25635753
Conditional regulation of Puf1p, Puf4p, and Puf5p activity alters YHB1 mRNA stability for a rapid response to toxic nitric oxide stress in yeast. PMID:25631823
Size-dependent leak of soluble and membrane proteins through the yeast nuclear pore complex. PMID:25631821
Diversity of the biosynthesis pathway for threonylcarbamoyladenosine (t(6)A), a universal modification of tRNA. PMID:25629598
Sec24 is a coincidence detector that simultaneously binds two signals to drive ER export. PMID:25619760
Plasmids for C-terminal tagging in Saccharomyces cerevisiae that contain improved GFP proteins, Envy and Ivy. PMID:25612242
Structure-based design of combinatorial mutagenesis libraries. PMID:25611189
Loss of APD1 in yeast confers hydroxyurea sensitivity suppressed by Yap1p transcription factor. PMID:25600293
Power(2): the power of yeast genetics applied to the powerhouse of the cell. PMID:25591985
Reliable cell cycle commitment in budding yeast is ensured by signal integration. PMID:25590650
The Erv41-Erv46 complex serves as a retrograde receptor to retrieve escaped ER proteins. PMID:25583996
An in vivo detection system for transient and low-abundant protein interactions and their kinetics in budding yeast. PMID:25582094
Dynamics of the lipid droplet proteome of the Oleaginous yeast rhodosporidium toruloides. PMID:25576482
Nur1 dephosphorylation confers positive feedback to mitotic exit phosphatase activation in budding yeast. PMID:25569132
Heterologous aggregates promote de novo prion appearance via more than one mechanism. PMID:25568955
TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease. PMID:25566323
Quality control of a cytoplasmic protein complex: chaperone motors and the ubiquitin-proteasome system govern the fate of orphan fatty acid synthase subunit Fas2 of yeast. PMID:25564609
Stochastic approach to the molecular counting problem in superresolution microscopy. PMID:25535361
Profile of Kazutoshi Mori and Peter Walter, 2014 Lasker Basic Medical Research awardees: The unfolded protein response. PMID:25480547
A lettuce (Lactuca sativa) homolog of human Nogo-B receptor interacts with cis-prenyltransferase and is necessary for natural rubber biosynthesis. PMID:25477521
An efficient protein complex mining algorithm based on Multistage Kernel Extension. PMID:25474367
Detecting functional divergence after gene duplication through evolutionary changes in posttranslational regulatory sequences. PMID:25474245
Granules harboring translationally active mRNAs provide a platform for P-body formation following stress. PMID:25437551
Surveying the floodgates: estimating protein flux into the endoplasmic reticulum lumen in Saccharomyces cerevisiae. PMID:25431559
Local statistics allow quantification of cell-to-cell variability from high-throughput microscope images. PMID:25398614
Double-stranded DNA-dependent ATPase Irc3p is directly involved in mitochondrial genome maintenance. PMID:25389272
Cdc42p-interacting protein Bem4p regulates the filamentous-growth mitogen-activated protein kinase pathway. PMID:25384973
The subunits of the S-phase checkpoint complex Mrc1/Tof1/Csm3: dynamics and interdependence. PMID:25379053
Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling. PMID:25378625
Accurate protein complex retrieval by affinity enrichment mass spectrometry (AE-MS) rather than affinity purification mass spectrometry (AP-MS). PMID:25363814
Changes in SAM2 expression affect lactic acid tolerance and lactic acid production in Saccharomyces cerevisiae. PMID:25359316
Deteriorated stress response in stationary-phase yeast: Sir2 and Yap1 are essential for Hsf1 activation by heat shock and oxidative stress, respectively. PMID:25356557
Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress. PMID:25344756
Comparative and mechanistic genotoxicity assessment of nanomaterials via a quantitative toxicogenomics approach across multiple species. PMID:25338269
Protein acetylation and acetyl coenzyme a metabolism in budding yeast. PMID:25326522
The exosome-binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase. PMID:25319414
The Hsp90-dependent proteome is conserved and enriched for hub proteins with high levels of protein-protein connectivity. PMID:25316598
Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos. PMID:25294944
A systematic analysis of protein palmitoylation in Caenorhabditis elegans. PMID:25277130
Loss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylation. PMID:25258318
Pulsatile dynamics in the yeast proteome. PMID:25220054
Genome-wide profiling of untranslated regions by paired-end ditag sequencing reveals unexpected transcriptome complexity in yeast. PMID:25213602
Protein expression analyses at the single cell level. PMID:25197931
Mother-daughter asymmetry of pH underlies aging and rejuvenation in yeast. PMID:25190112
Overexpression of p49/STRAP alters cellular cytoskeletal structure and gross anatomy in mice. PMID:25183317
Superglue from bacteria: unbreakable bridges for protein nanotechnology. PMID:25168413
Average oxidation state of carbon in proteins. PMID:25165594
Fractionation profiling: a fast and versatile approach for mapping vesicle proteomes and protein-protein interactions. PMID:25165137
Identifying transcription factor complexes and their roles. PMID:25161228
Assembly and dynamics of the autophagy-initiating Atg1 complex. PMID:25139988
Label-free protein quantification for plant Golgi protein localization and abundance. PMID:25122472
Proteasome assembly. PMID:25107634
Dual N- and C-terminal helices are required for endoplasmic reticulum and lipid droplet association of alcohol acetyltransferases in Saccharomyces cerevisiae. PMID:25093817
A single acetylation of 18 S rRNA is essential for biogenesis of the small ribosomal subunit in Saccharomyces cerevisiae. PMID:25086048
Separate responses of karyopherins to glucose and amino acid availability regulate nucleocytoplasmic transport. PMID:25057022
Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs. PMID:25056316
Lessons from yeast: the spindle pole body and the centrosome. PMID:25047610
Prion-promoted phosphorylation of heterologous amyloid is coupled with ubiquitin-proteasome system inhibition and toxicity. PMID:25039275
Cross kingdom functional conservation of the core universally conserved threonylcarbamoyladenosine tRNA synthesis enzymes. PMID:25038083
The long and viscous road: uncovering nuclear diffusion barriers in closed mitosis. PMID:25032937
Proteome-wide remodeling of protein location and function by stress. PMID:25028499
BiP clustering facilitates protein folding in the endoplasmic reticulum. PMID:24991821
Yeast mating and image-based quantification of spatial pattern formation. PMID:24967739
The ESCRT-III adaptor protein Bro1 controls functions of regulator for free ubiquitin chains 1 (Rfu1) in ubiquitin homeostasis. PMID:24962567
Phospholipid transport via mitochondria. PMID:24954234
A microfluidic system for studying ageing and dynamic single-cell responses in budding yeast. PMID:24950344
MPV17L2 is required for ribosome assembly in mitochondria. PMID:24948607
The emergence of proteome-wide technologies: systematic analysis of proteins comes of age. PMID:24938631
Unidirectional P-body transport during the yeast cell cycle. PMID:24918601
Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance. PMID:24916159
Normal telomere length maintenance in Saccharomyces cerevisiae requires nuclear import of the ever shorter telomeres 1 (Est1) protein via the importin alpha pathway. PMID:24906415
Histidine methylation of yeast ribosomal protein Rpl3p is required for proper 60S subunit assembly. PMID:24865971
Specific analogues uncouple transport, signalling, oligo-ubiquitination and endocytosis in the yeast Gap1 amino acid transceptor. PMID:24852066
LocTree3 prediction of localization. PMID:24848019
MFS transporters required for multidrug/multixenobiotic (MD/MX) resistance in the model yeast: understanding their physiological function through post-genomic approaches. PMID:24847282
How the nucleus copes with proteotoxic stress. PMID:24845679
Only a subset of the PAB1-mRNP proteome is present in mRNA translation complexes. PMID:24838188
Heritability and genetic basis of protein level variation in an outbred population. PMID:24823668
Budding yeast for budding geneticists: a primer on the Saccharomyces cerevisiae model system. PMID:24807111
mRNA quality control at the 5' end. PMID:24793761
Reversible protein inactivation by optogenetic trapping in cells. PMID:24793453
A conserved and essential basic region mediates tRNA binding to the Elp1 subunit of the Saccharomyces cerevisiae Elongator complex. PMID:24750273
Circularly permuted tRNA genes: their expression and implications for their physiological relevance and development. PMID:24744771
Contact of cis-Golgi with ER exit sites executes cargo capture and delivery from the ER. PMID:24728174
Regulation of a transcription factor network by Cdk1 coordinates late cell cycle gene expression. PMID:24714560
Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture. PMID:24714493
Long-term single cell analysis of S. pombe on a microfluidic microchemostat array. PMID:24710337
Physical and functional interaction between the methyltransferase Bud23 and the essential DEAH-box RNA helicase Ecm16. PMID:24710271
Rapid identification of mRNA processing defects with a novel single-cell yeast reporter. PMID:24671766
A versatile assay for RNA-binding proteins in living cells. PMID:24664470
The ribosomal biogenesis protein Utp21 interacts with Hsp90 and has differing requirements for Hsp90-associated proteins. PMID:24647762
Vhs2 is a novel regulator of septin dynamics in budding yeast. PMID:24646733
SpyLigase peptide-peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture. PMID:24639550
Identification and characterization of a drug-sensitive strain enables puromycin-based translational assays in Saccharomyces cerevisiae. PMID:24610064
Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins. PMID:24603469
Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics. PMID:24599962
Application of a new dual localization-affinity purification tag reveals novel aspects of protein kinase biology in Aspergillus nidulans. PMID:24599037
Visualizing protein movement on DNA at the single-molecule level using DNA curtains. PMID:24598576
RANKING RELATIONS USING ANALOGIES IN BIOLOGICAL AND INFORMATION NETWORKS. PMID:24587838
COMPARTMENTS: unification and visualization of protein subcellular localization evidence. PMID:24573882
Detecting overlapping protein complexes in PPI networks based on robustness. PMID:24565162
PLW: Probabilistic Local Walks for detecting protein complexes from protein interaction networks. PMID:24564427
Nucleolar GTPase NOG-1 regulates development, fat storage, and longevity through insulin/IGF signaling in C. elegans. PMID:24552710
Unexpected function of the glucanosyltransferase Gas1 in the DNA damage response linked to histone H3 acetyltransferases in Saccharomyces cerevisiae. PMID:24532730
Endolysosomal membrane trafficking complexes drive nutrient-dependent TORC1 signaling to control cell growth in Saccharomyces cerevisiae. PMID:24514902
Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae. PMID:24489116
A proteomic survey of widespread protein aggregation in yeast. PMID:24488121
gitter: a robust and accurate method for quantification of colony sizes from plate images. PMID:24474170
The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. PMID:24470217
Predicting human protein subcellular locations by the ensemble of multiple predictors via protein-protein interaction network with edge clustering coefficients. PMID:24466278
Ubiquitin-related modifiers of Arabidopsis thaliana influence root development. PMID:24466270
Aim44p regulates phosphorylation of Hof1p to promote contractile ring closure during cytokinesis in budding yeast. PMID:24451263
Plus ça change - evolutionary sequence divergence predicts protein subcellular localization signals. PMID:24438075
mRNA localization to P-bodies in yeast is bi-phasic with many mRNAs captured in a late Bfr1p-dependent wave. PMID:24424022
A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis. PMID:24403601
Genetics of single-cell protein abundance variation in large yeast populations. PMID:24402228
A visual screen of protein localization during sporulation identifies new components of prospore membrane-associated complexes in budding yeast. PMID:24390141
Where is mTOR and what is it doing there? PMID:24385483
Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences. PMID:24348511
Linkage of oxidative stress and mitochondrial dysfunctions to spontaneous culture degeneration in Aspergillus nidulans. PMID:24345786
Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae. PMID:24335083
Role of Loc1p in assembly and reorganization of nuclear ASH1 messenger ribonucleoprotein particles in yeast. PMID:24324176
Heterodimeric protein complex identification by naïve Bayes classifiers. PMID:24299017
Cellular distribution of copper to superoxide dismutase involves scaffolding by membranes. PMID:24297923
Genetic robustness and functional evolution of gene duplicates. PMID:24288370
A quantitative liposome microarray to systematically characterize protein-lipid interactions. PMID:24270602
Lipid droplet autophagy in the yeast Saccharomyces cerevisiae. PMID:24258026
tRNA 3' processing in yeast involves tRNase Z, Rex1, and Rrp6. PMID:24249226
Enhancing protein disaggregation restores proteasome activity in aged cells. PMID:24243762
Deorphanizing the human transmembrane genome: A landscape of uncharacterized membrane proteins. PMID:24241348
The protein quality control system manages plant defence compound synthesis. PMID:24213631
SNAP-, CLIP- and Halo-tag labelling of budding yeast cells. PMID:24205303
Mmi1, the yeast homologue of mammalian TCTP, associates with stress granules in heat-shocked cells and modulates proteasome activity. PMID:24204967
tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humans. PMID:24204302
Glu-44 in the amino-terminal α-helix of yeast vacuolar ATPase E subunit (Vma4p) has a role for VoV1 assembly. PMID:24196958
PAH1-encoded phosphatidate phosphatase plays a role in the growth phase- and inositol-mediated regulation of lipid synthesis in Saccharomyces cerevisiae. PMID:24196957
Yeast PPR proteins, watchdogs of mitochondrial gene expression. PMID:24184848
LoQAtE--Localization and Quantitation ATlas of the yeast proteomE. A new tool for multiparametric dissection of single-protein behavior in response to biological perturbations in yeast. PMID:24150937
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease. PMID:24129513
A conserved protein with AN1 zinc finger and ubiquitin-like domains modulates Cdc48 (p97) function in the ubiquitin-proteasome pathway. PMID:24121501
Mitochondrial aminopeptidase deletion increases chronological lifespan and oxidative stress resistance while decreasing respiratory metabolism in S. cerevisiae. PMID:24116217
High-resolution restoration of 3D structures from widefield images with extreme low signal-to-noise-ratio. PMID:24106307
Compositional and structural analysis of selected chromosomal domains from Saccharomyces cerevisiae. PMID:24106087
An Iml3-Chl4 heterodimer links the core centromere to factors required for accurate chromosome segregation. PMID:24075991
Functional genomics in the study of yeast cell polarity: moving in the right direction. PMID:24062589
The emergence of lipid droplets in yeast: current status and experimental approaches. PMID:24057105
SPO71 encodes a developmental stage-specific partner for Vps13 in Saccharomyces cerevisiae. PMID:24036347
Automated quantification of the subcellular localization of multicompartment proteins via Q-SCAn. PMID:24034606
Peroxiredoxin chaperone activity is critical for protein homeostasis in zinc-deficient yeast. PMID:24022485
A chemostat array enables the spatio-temporal analysis of the yeast proteome. PMID:24019481
Mapping yeast transcriptional networks. PMID:24018767
Measurement and modeling of transcriptional noise in the cell cycle regulatory network. PMID:24013422
Using variability in gene expression as a tool for studying gene regulation. PMID:23996796
Continuous high-resolution microscopic observation of replicative aging in budding yeast. PMID:23995364
Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress. PMID:23993092
Gcn5 and sirtuins regulate acetylation of the ribosomal protein transcription factor Ifh1. PMID:23973296
Visualizing cellular machines with colocalization single molecule microscopy. PMID:23970346
Conserved regulators of nucleolar size revealed by global phenotypic analyses. PMID:23962978
Global analysis of fission yeast mating genes reveals new autophagy factors. PMID:23950735
Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes. PMID:23943876
Genetic and nongenetic determinants of cell growth variation assessed by high-throughput microscopy. PMID:23938868
Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae. PMID:23935119
The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function. PMID:23934994
Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins. PMID:23934110
Non-targeted identification of prions and amyloid-forming proteins from yeast and mammalian cells. PMID:23926098
Regulation of ER-phagy by a Ypt/Rab GTPase module. PMID:23924895
Clathrin coat disassembly by the yeast Hsc70/Ssa1p and auxilin/Swa2p proteins observed by single-particle burst analysis spectroscopy. PMID:23913685
Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively. PMID:23913415
The transience of transient overexpression. PMID:23900254
The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p. PMID:23897890
Redox regulation of an AP-1-like transcription factor, YapA, in the fungal symbiont Epichloe festucae. PMID:23893078
A new strategy for gene targeting and functional proteomics using the DT40 cell line. PMID:23892402
Physiological role of Acyl coenzyme A synthetase homologs in lipid metabolism in Neurospora crassa. PMID:23873861
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. PMID:23849981
Chromatin tandem affinity purification sequencing. PMID:23845964
A guide to best practices for Gene Ontology (GO) manual annotation. PMID:23842463
Involvement of MoVMA11, a Putative Vacuolar ATPase c' Subunit, in Vacuolar Acidification and Infection-Related Morphogenesis of Magnaporthe oryzae. PMID:23826342
Fluorescent protein tagging as a tool to define the subcellular distribution of proteins in plants. PMID:23805149
Centromere binding and a conserved role in chromosome stability for SUMO-dependent ubiquitin ligases. PMID:23785440
Unsupervised clustering of subcellular protein expression patterns in high-throughput microscopy images reveals protein complexes and functional relationships between proteins. PMID:23785265
RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes. PMID:23778934
A light-inducible organelle-targeting system for dynamically activating and inactivating signaling in budding yeast. PMID:23761071
Agp2, a member of the yeast amino acid permease family, positively regulates polyamine transport at the transcriptional level. PMID:23755272
Spatial reorganization of Saccharomyces cerevisiae enolase to alter carbon metabolism under hypoxia. PMID:23748432
Improving the measurement of semantic similarity between gene ontology terms and gene products: insights from an edge- and IC-based hybrid method. PMID:23741529
A global S. cerevisiae small ubiquitin-related modifier (SUMO) system interactome. PMID:23712011
Organelle acidification is important for localisation of vacuolar proteins in Saccharomyces cerevisiae. PMID:23708375
Recombination-induced tag exchange (RITE) cassette series to monitor protein dynamics in Saccharomyces cerevisiae. PMID:23708297
Ptc6 is required for proper rapamycin-induced down-regulation of the genes coding for ribosomal and rRNA processing proteins in S. cerevisiae. PMID:23704987
Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways. PMID:23695164
ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast. PMID:23682313
Characterization of an M28 metalloprotease family member residing in the yeast vacuole. PMID:23679341
Proteome-wide discovery of mislocated proteins in cancer. PMID:23674306
Ligand-induced activation of a formin-NPF pair leads to collaborative actin nucleation. PMID:23671312
The spatial distribution of the exocyst and actin cortical patches is sufficient to organize hyphal tip growth. PMID:23666623
Microfluidic genome-wide profiling of intrinsic electrical properties in Saccharomyces cerevisiae. PMID:23661198
Detection and characterization of protein interactions in vivo by a simple live-cell imaging method. PMID:23658712
Transfer RNA post-transcriptional processing, turnover, and subcellular dynamics in the yeast Saccharomyces cerevisiae. PMID:23633143
Tiered assembly of the yeast Far3-7-8-9-10-11 complex at the endoplasmic reticulum. PMID:23625923
Silencing of Nicotiana benthamiana Neuroblastoma-Amplified Gene causes ER stress and cell death. PMID:23621803
Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system. PMID:23620299
N-terminal acetylation by NatC is not a general determinant for substrate subcellular localization in Saccharomyces cerevisiae. PMID:23613772
The rRNA methyltransferase Bud23 shows functional interaction with components of the SSU processome and RNase MRP. PMID:23604635
Evolutionary capacitance and control of protein stability in protein-protein interaction networks. PMID:23592969
Lsb1 is a negative regulator of las17 dependent actin polymerization involved in endocytosis. PMID:23577202
mChIP-KAT-MS, a method to map protein interactions and acetylation sites for lysine acetyltransferases. PMID:23572591
Structural and functional characterization of a phosphatase domain within yeast general transcription factor IIIC. PMID:23569204
Identification of a novel methyltransferase, Bmt2, responsible for the N-1-methyl-adenosine base modification of 25S rRNA in Saccharomyces cerevisiae. PMID:23558746
Temporal system-level organization of the switch from glycolytic to gluconeogenic operation in yeast. PMID:23549479
Systematic analysis of γ-aminobutyric acid (GABA) metabolism and function in the social amoeba Dictyostelium discoideum. PMID:23548898
Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. PMID:23547032
Structural and functional analysis of the U3 snoRNA binding protein Rrp9. PMID:23509373
A novel single-cell screening platform reveals proteome plasticity during yeast stress responses. PMID:23509072
Assembly of the 20S proteasome. PMID:23507199
The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway. PMID:23503588
A network of genes connects polyglutamine toxicity to ploidy control in yeast. PMID:23481379
A safeguard mechanism regulates Rho GTPases to coordinate cytokinesis with the establishment of cell polarity. PMID:23468594
Spatial and functional organization of mitochondrial protein network. PMID:23466738
Heat shock-induced accumulation of translation elongation and termination factors precedes assembly of stress granules in S. cerevisiae. PMID:23451152
Actin dosage lethality screening in yeast mediated by selective ploidy ablation reveals links to urmylation/wobble codon recognition and chromosome stability. PMID:23450344
Protein complex-based analysis framework for high-throughput data sets. PMID:23443684
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. PMID:23435261
Metabolic fate of the increased yeast amino Acid uptake subsequent to catabolite derepression. PMID:23431419
Quantitative analysis of chaperone network throughput in budding yeast. PMID:23420633
Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity. PMID:23417976
A genomic toolkit to investigate kinesin and myosin motor function in cells. PMID:23417121
Concise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic disease. PMID:23413375
Genetic networks inducing invasive growth in Saccharomyces cerevisiae identified through systematic genome-wide overexpression. PMID:23410832
The RNA exosome complex central channel controls both exonuclease and endonuclease Dis3 activities in vivo and in vitro. PMID:23404585
Genome-Wide Functional and Stress Response Profiling Reveals Toxic Mechanism and Genes Required for Tolerance to Benzo[a]pyrene in S. cerevisiae. PMID:23403841
Genome-wide bimolecular fluorescence complementation analysis of SUMO interactome in yeast. PMID:23403034
Secretory protein biogenesis and traffic in the early secretory pathway. PMID:23396477
Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm. PMID:23396276
Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae. PMID:23383298
The highly conserved COPII coat complex sorts cargo from the endoplasmic reticulum and targets it to the golgi. PMID:23378591
The contribution of systematic approaches to characterizing the proteins and functions of the endoplasmic reticulum. PMID:23359093
Heterologous gln/asn-rich proteins impede the propagation of yeast prions by altering chaperone availability. PMID:23358669
Identification and physiological characterization of phosphatidic acid phosphatase enzymes involved in triacylglycerol biosynthesis in Streptomyces coelicolor. PMID:23356794
Global analysis of condition-specific subcellular protein distribution and abundance. PMID:23349476
Tunable signal processing through modular control of transcription factor translocation. PMID:23349292
Characterization of the yeast actin patch protein App1p phosphatidate phosphatase. PMID:23335564
Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast. PMID:23335509
Vps factors are required for efficient transcription elongation in budding yeast. PMID:23335340
Candidate target genes for the Saccharomyces cerevisiae transcription factor, Yap2. PMID:23334931
Analysis of ER resident proteins in Saccharomyces cerevisiae: implementation of H/KDEL retrieval sequences. PMID:23324027
Approaching the functional annotation of fungal virulence factors using cross-species genetic interaction profiling. PMID:23300468
Lipid droplets and peroxisomes: key players in cellular lipid homeostasis or a matter of fat--store 'em up or burn 'em down. PMID:23275493
Dissection of DNA damage responses using multiconditional genetic interaction maps. PMID:23273983
The yeast eukaryotic translation initiation factor 2B translation initiation complex interacts with the fatty acid synthesis enzyme YBR159W and endoplasmic reticulum membranes. PMID:23263984
Spatiotemporal analysis of organelle and macromolecular complex inheritance. PMID:23248297
A gene ontology inferred from molecular networks. PMID:23242164
The fermentation stress response protein Aaf1p/Yml081Wp regulates acetate production in Saccharomyces cerevisiae. PMID:23240040
Double-negative feedback between S-phase cyclin-CDK and CKI generates abruptness in the G1/S switch. PMID:23230424
Experimental evidence validating the computational inference of functional associations from gene fusion events: a critical survey. PMID:23220349
Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked. PMID:23203805
Las1 interacts with Grc3 polynucleotide kinase and is required for ribosome synthesis in Saccharomyces cerevisiae. PMID:23175604
An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. PMID:23172144
Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapy. PMID:23169667
Saccharomyces cerevisiae Env7 is a novel serine/threonine kinase 16-related protein kinase and negatively regulates organelle fusion at the lysosomal vacuole. PMID:23166297
Proteomics-based methods for discovery, quantification, and validation of protein-protein interactions. PMID:23157382
Single cell analysis of yeast replicative aging using a new generation of microfluidic device. PMID:23144860
Interactions of subunit CCT3 in the yeast chaperonin CCT/TRiC with Q/N-rich proteins revealed by high-throughput microscopy analysis. PMID:23112166
Identifying novel protein complexes in cancer cells using epitope-tagging of endogenous human genes and affinity-purification mass spectrometry. PMID:23106643
Nonlinear fitness consequences of variation in expression level of a eukaryotic gene. PMID:23104081
Interchromosomal clustering of active genes at the nuclear pore complex. PMID:23099887
Sequence requirements for localization and packaging of Ty3 retroelement RNA. PMID:23073180
The Saccharomyces cerevisiae actin patch protein App1p is a phosphatidate phosphatase enzyme. PMID:23071111
Dynamic reorganization of metabolic enzymes into intracellular bodies. PMID:23057741
Aminopropyltransferases involved in polyamine biosynthesis localize preferentially in the nucleus of plant cells. PMID:23056524
Discovering protein complexes in protein interaction networks via exploring the weak ties effect. PMID:23046740
Genome-wide ribosome profiling reveals complex translational regulation in response to oxidative stress. PMID:23045643
The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent manner. PMID:23045398
The conserved Bud20 zinc finger protein is a new component of the ribosomal 60S subunit export machinery. PMID:23045392
MRN1 implicates chromatin remodeling complexes and architectural factors in mRNA maturation. PMID:23028530
An RMND1 Mutation causes encephalopathy associated with multiple oxidative phosphorylation complex deficiencies and a mitochondrial translation defect. PMID:23022098
S-adenosyl-L-homocysteine hydrolase and methylation disorders: yeast as a model system. PMID:23017368
Intermembrane space proteome of yeast mitochondria. PMID:22984289
Identification of elongation factor G as the conserved cellular target of argyrin B. PMID:22970117
Structure and function in the budding yeast nucleus. PMID:22964839
Dxo1 is a new type of eukaryotic enzyme with both decapping and 5'-3' exoribonuclease activity. PMID:22961381
Role of Mex67-Mtr2 in the nuclear export of 40S pre-ribosomes. PMID:22956913
The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits. PMID:22956767
Oxidative stress responses involve oxidation of a conserved ubiquitin pathway enzyme. PMID:22949505
Counting protein molecules using quantitative fluorescence microscopy. PMID:22948030
Visualizing global effects of the DNA damage response. PMID:22945255
The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. PMID:22932476
SCS3 and YFT2 link transcription of phospholipid biosynthetic genes to ER stress and the UPR. PMID:22927826
Air proteins control differential TRAMP substrate specificity for nuclear RNA surveillance. PMID:22923767
The three clades of the telomere-associated TLO gene family of Candida albicans have different splicing, localization, and expression features. PMID:22923044
Systematic dissection of roles for chromatin regulators in a yeast stress response. PMID:22912562
The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation. PMID:22910358
Phosphatidate phosphatase, a key regulator of lipid homeostasis. PMID:22910056
Hsp110 is required for spindle length control. PMID:22908312
Incidence of genome structure, DNA asymmetry, and cell physiology on T-DNA integration in chromosomes of the phytopathogenic fungus Leptosphaeria maculans. PMID:22908038
A genome-scale resource for in vivo tag-based protein function exploration in C. elegans. PMID:22901814
Polyploidy and the evolution of complex traits. PMID:22900230
PKA isoforms coordinate mRNA fate during nutrient starvation. PMID:22899713
A yeast model for amyloid-β aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity. PMID:22888099
Profiling of cytosolic and peroxisomal acetyl-CoA metabolism in Saccharomyces cerevisiae. PMID:22876324
NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast. PMID:22848679
Prediction and analysis of the protein interactome in Pseudomonas aeruginosa to enable network-based drug target selection. PMID:22848443
Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. PMID:22842922
Scp160-dependent mRNA trafficking mediates pheromone gradient sensing and chemotropism in yeast. PMID:22832273
Heat shock protein 90 is required for conidiation and cell wall integrity in Aspergillus fumigatus. PMID:22822234
Transfer of Ho endonuclease and Ufo1 to the proteasome by the UbL-UbA shuttle protein, Ddi1, analysed by complex formation in vitro. PMID:22815701
The Reb1-homologue Ydr026c/Nsi1 is required for efficient RNA polymerase I termination in yeast. PMID:22805593
N-glycosylation of enhanced aromatic sequons to increase glycoprotein stability. PMID:22782562
Minimalist ensemble algorithms for genome-wide protein localization prediction. PMID:22759391
A quantitative model of the initiation of DNA replication in Saccharomyces cerevisiae predicts the effects of system perturbations. PMID:22738223
Use of the novel technique of analytical ultracentrifugation with fluorescence detection system identifies a 77S monosomal translation complex. PMID:22733647
A deubiquitylating complex required for neosynthesis of a yeast mitochondrial ATP synthase subunit. PMID:22723847
The Saccharomyces cerevisiae Hot1p regulated gene YHR087W (HGI1) has a role in translation upon high glucose concentration stress. PMID:22720784
Network compression as a quality measure for protein interaction networks. PMID:22719828
In vivo approaches to dissecting the function of RNA helicases in eukaryotic ribosome assembly. PMID:22713326
Zinc-finger nuclease-mediated targeted insertion of reporter genes for quantitative imaging of gene expression in sea urchin embryos. PMID:22711830
Nuclear envelope morphology constrains diffusion and promotes asymmetric protein segregation in closed mitosis. PMID:22711697
Cell polarization and cytokinesis in budding yeast. PMID:22701052
Actin depolymerization drives actomyosin ring contraction during budding yeast cytokinesis. PMID:22698284
Regulation of lipid metabolism: a tale of two yeasts. PMID:22694927
Integrity of the P-site is probed during maturation of the 60S ribosomal subunit. PMID:22689654
Evolution and diversification of the organellar release factor family. PMID:22688947
The DEAD-box RNA helicase Dbp2 connects RNA quality control with repression of aberrant transcription. PMID:22679025
The yeast ubr1 ubiquitin ligase participates in a prominent pathway that targets cytosolic thermosensitive mutants for degradation. PMID:22670231
Acetate regulation of spore formation is under the control of the Ras/cyclic AMP/protein kinase A pathway and carbon dioxide in Saccharomyces cerevisiae. PMID:22660623
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. PMID:22660414
A plethora of virulence strategies hidden behind nuclear targeting of microbial effectors. PMID:22639625
A lysine-rich region within fungal BAG domain-containing proteins mediates a novel association with ribosomes. PMID:22635919
A systematic approach to pair secretory cargo receptors with their cargo suggests a mechanism for cargo selection by Erv14. PMID:22629230
Nucleoplasmic/nucleolar translocation and identification of a nuclear localization signal (NLS) in Dictyostelium BAF60a/SMARCD1 homologue Snf12. PMID:22623154
Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata. PMID:22615574
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters. PMID:22609971
Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectant. PMID:22589700
Exploring the yeast acetylome using functional genomics. PMID:22579291
Transcription factor binding to a DNA zip code controls interchromosomal clustering at the nuclear periphery. PMID:22579222
RNA-dependent regulation of the cell wall stress response. PMID:22576366
Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae. PMID:22570702
The Golgi-localized Arabidopsis endomembrane protein12 contains both endoplasmic reticulum export and Golgi retention signals at its C terminus. PMID:22570441
Sumoylation regulates Kap114-mediated nuclear transport. PMID:22562154
Hul5 ubiquitin ligase: good riddance to bad proteins. PMID:22561164
Patchwork organization of the yeast plasma membrane into numerous coexisting domains. PMID:22544065
A simple, versatile method for GFP-based super-resolution microscopy via nanobodies. PMID:22543348
Fission yeast Lem2 and Man1 perform fundamental functions of the animal cell nuclear lamina. PMID:22540024
The proteomics of lipid droplets: structure, dynamics, and functions of the organelle conserved from bacteria to humans. PMID:22534641
Spatial localisation of chaperone distribution in the endoplasmic reticulum of yeast. PMID:22519358
GAMETOPHYTE DEFECTIVE 1, a putative subunit of RNases P/MRP, is essential for female gametogenesis and male competence in Arabidopsis. PMID:22509260
Regulation of selective autophagy onset by a Ypt/Rab GTPase module. PMID:22509044
Genetic evidence links the ASTRA protein chaperone component Tti2 to the SAGA transcription factor Tra1. PMID:22505622
Trm112 is required for Bud23-mediated methylation of the 18S rRNA at position G1575. PMID:22493060
Mitotic spindle form and function. PMID:22491889
The MPS1 family of protein kinases. PMID:22482908
Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast. PMID:22473760
Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast. PMID:22470557
Using bleach-chase to measure protein half-lives in living cells. PMID:22461069
Evolutionary and genetic analyses of mitochondrial translation initiation factors identify the missing mitochondrial IF3 in S. cerevisiae. PMID:22457064
VPS13 regulates membrane morphogenesis during sporulation in Saccharomyces cerevisiae. PMID:22442115
Promoter nucleosome organization shapes the evolution of gene expression. PMID:22438828
Rewiring of posttranscriptional RNA regulons: Puf4p in fungi as an example. PMID:22438588
The Saccharomyces cerevisiae Nrd1-Nab3 transcription termination pathway acts in opposition to Ras signaling and mediates response to nutrient depletion. PMID:22431520
Modular TRAPP complexes regulate intracellular protein trafficking through multiple Ypt/Rab GTPases in Saccharomyces cerevisiae. PMID:22426882
Detecting overlapping protein complexes in protein-protein interaction networks. PMID:22426491
Human RioK3 is a novel component of cytoplasmic pre-40S pre-ribosomal particles. PMID:22418843
Chaperones divide yeast proteins into classes of expression level and evolutionary rate. PMID:22417914
Ccr4-Not complex: the control freak of eukaryotic cells. PMID:22416820
System-level insights into yeast metabolism by thermodynamic analysis of elementary flux modes. PMID:22416224
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly. PMID:22416125
Combinatorial complexity and compositional drift in protein interaction networks. PMID:22412851
Beyond tRNA cleavage: novel essential function for yeast tRNA splicing endonuclease unrelated to tRNA processing. PMID:22391451
TULIPs: tunable, light-controlled interacting protein tags for cell biology. PMID:22388287
Identification of yeast genes involved in k homeostasis: loss of membrane traffic genes affects k uptake. PMID:22384317
Saccharomyces cerevisiae Cmr1 protein preferentially binds to UV-damaged DNA in vitro. PMID:22367945
Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin. PMID:22366317
Nsi1 plays a significant role in the silencing of ribosomal DNA in Saccharomyces cerevisiae. PMID:22362748
Widespread mRNA association with cytoskeletal motor proteins and identification and dynamics of myosin-associated mRNAs in S. cerevisiae. PMID:22359641
Negative feedback confers mutational robustness in yeast transcription factor regulation. PMID:22355134
GFP tagging sheds light on protein translocation: implications for key methods in cell biology. PMID:22349212
Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. PMID:22345606
Phosphoinositide-mediated clathrin adaptor progression at the trans-Golgi network. PMID:22344030
Two cation transporters Ena1 and Nha1 cooperatively modulate ion homeostasis, antifungal drug resistance, and virulence of Cryptococcus neoformans via the HOG pathway. PMID:22343280
The histone deacetylase Hos2 forms an Hsp42-dependent cytoplasmic granule in quiescent yeast cells. PMID:22337769
PP4 dephosphorylates Maf1 to couple multiple stress conditions to RNA polymerase III repression. PMID:22333918
Inhibition of copper uptake in yeast reveals the copper transporter Ctr1p as a potential molecular target of saxitoxin. PMID:22304436
Controlling lipid fluxes at glycerol-3-phosphate acyltransferase step in yeast: unique contribution of Gat1p to oleic acid-induced lipid particle formation. PMID:22267742
Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry. PMID:22260433
Plate-based transfection and culturing technique for genetic manipulation of Plasmodium falciparum. PMID:22257490
A conserved membrane-binding domain targets proteins to organelle contact sites. PMID:22250200
The role of PAS kinase in PASsing the glucose signal. PMID:22219681
Kar2p availability defines distinct forms of endoplasmic reticulum stress in living cells. PMID:22219379
Analysis of yeast endocytic site formation and maturation through a regulatory transition point. PMID:22190733
Distinct contributions of vacuolar Qabc- and R-SNARE proteins to membrane fusion specificity. PMID:22174414
Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway. PMID:22174182
Live-cell assays to identify regulators of ER-to-Golgi trafficking. PMID:22132776
Motility and segregation of Hsp104-associated protein aggregates in budding yeast. PMID:22118470
A conserved transcriptional regulator governs fungal morphology in widely diverged species. PMID:22095082
Yeast: an experimental organism for 21st Century biology. PMID:22084421
A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. PMID:22056673
Oscillatory dynamics of cell cycle proteins in single yeast cells analyzed by imaging cytometry. PMID:22046265
An in silico approach combined with in vivo experiments enables the identification of a new protein whose overexpression can compensate for specific respiratory defects in Saccharomyces cerevisiae. PMID:22027258
A genomic integration method for the simultaneous visualization of endogenous mRNAs and their translation products in living yeast. PMID:22025736
System-wide perturbation analysis with nearly complete coverage of the yeast proteome by single-shot ultra HPLC runs on a bench top Orbitrap. PMID:22021278
Dual channel rank-based intensity weighting for quantitative co-localization of microscopy images. PMID:22017789
Removing bias against membrane proteins in interaction networks. PMID:22011625
Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. PMID:22002106
Learning cellular sorting pathways using protein interactions and sequence motifs. PMID:21999284
Dithizone staining of intracellular zinc: an unexpected and versatile counterscreen for auxotrophic marker genes in Saccharomyces cerevisiae. PMID:21998704
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. PMID:21987634
Hul5 HECT ubiquitin ligase plays a major role in the ubiquitylation and turnover of cytosolic misfolded proteins. PMID:21983566
Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. PMID:21978764
Using quantitative redox proteomics to dissect the yeast redoxome. PMID:21976664
Differential chromatin proteomics of the MMS-induced DNA damage response in yeast. PMID:21967861
Saccharomyces cerevisiae Ngl3p is an active 3'-5' exonuclease with a specificity towards poly-A RNA reminiscent of cellular deadenylases. PMID:21965533
The conserved foot domain of RNA pol II associates with proteins involved in transcriptional initiation and/or early elongation. PMID:21954159
The nucleolar protein Nop19p interacts preferentially with Utp25p and Dhr2p and is essential for the production of the 40S ribosomal subunit in Saccharomyces cerevisiae. PMID:21941128
Maf1 protein, repressor of RNA polymerase III, indirectly affects tRNA processing. PMID:21940626
Optimization of combinatorial mutagenesis. PMID:21923411
Seamless gene tagging by endonuclease-driven homologous recombination. PMID:21915245
A genome-wide immunodetection screen in S. cerevisiae uncovers novel genes involved in lysosomal vacuole function and morphology. PMID:21912603
Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification. PMID:21912530
Substrate analysis of the Pneumocystis carinii protein kinases PcCbk1 and PcSte20 using yeast proteome microarrays provides a novel method for Pneumocystis signalling biology. PMID:21905091
Hsp90 and client protein maturation. PMID:21898225
Identification of novel proteins associated with yeast snR30 small nucleolar RNA. PMID:21893585
GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein. PMID:21844196
Glucose regulates clathrin adaptors at the trans-Golgi network and endosomes. PMID:21832155
Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis. PMID:21824003
Quantitative fluorescence imaging of protein diffusion and interaction in living cells. PMID:21822256
Crystallization and preliminary X-ray analysis of the yeast tRNA-thiouridine modification protein 1 (Tum1p). PMID:21821903
Reporter mRNAs cleaved by Rnt1p are exported and degraded in the cytoplasm. PMID:21821655
The myosin-related motor protein Myo2 is an essential mediator of bud-directed mitochondrial movement in yeast. PMID:21807878
Systematic discovery of unannotated genes in 11 yeast species using a database of orthologous genomic segments. PMID:21791067
Small open reading frames: current prediction techniques and future prospect. PMID:21787300
Central dogma at the single-molecule level in living cells. PMID:21776076
Identification of an evolutionarily conserved family of inorganic polyphosphate endopolyphosphatases. PMID:21775424
Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes. PMID:21765803
Probing of the nuclear import and export signals and subcellular transport mechanism of varicella-zoster virus tegument protein open reading frame 10. PMID:21755366
Hypoxia elicits broad and systematic changes in protein subcellular localization. PMID:21753182
Functional dissection of the glucose signaling pathways that regulate the yeast glucose transporter gene (HXT) repressor Rgt1. PMID:21748783
Interactomic study on interaction between lipid droplets and mitochondria. PMID:21748599
A mitochondrial membrane exopolyphosphatase is modulated by, and plays a role in, the energy metabolism of hard tick Rhipicephalus (Boophilus) microplus embryos. PMID:21747692
Evaluation of FKBP and DHFR based destabilizing domains in Saccharomyces cerevisiae. PMID:21741238
Network clustering revealed the systemic alterations of mitochondrial protein expression. PMID:21738461
The coupling of pathways and processes through shared components. PMID:21714894
An intein with genetically selectable markers provides a new approach to internally label proteins with GFP. PMID:21708017
Integrated approaches reveal determinants of genome-wide binding and function of the transcription factor Pho4. PMID:21700227
DADA: Degree-Aware Algorithms for Network-Based Disease Gene Prioritization. PMID:21699738
Small sets of interacting proteins suggest functional linkage mechanisms via Bayesian analogical reasoning. PMID:21685095
A generalized model for multi-marker analysis of cell cycle progression in synchrony experiments. PMID:21685084
Construction of co-complex score matrix for protein complex prediction from AP-MS data. PMID:21685066
Yeast Bax inhibitor, Bxi1p, is an ER-localized protein that links the unfolded protein response and programmed cell death in Saccharomyces cerevisiae. PMID:21673967
Retrograde nuclear import of tRNA precursors is required for modified base biogenesis in yeast. PMID:21670254
Ubp15p, a ubiquitin hydrolase associated with the peroxisomal export machinery. PMID:21665945
Vacuolar import of phosphatidylcholine requires the ATP-binding cassette transporter Ybt1. PMID:21649806
Diverse protective roles of the actin cytoskeleton during oxidative stress. PMID:21634027
Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. PMID:21611156
Improved functional overview of protein complexes using inferred epistatic relationships. PMID:21605386
Resolution of gene regulatory conflicts caused by combinations of antibiotics. PMID:21596308
Deep and highly sensitive proteome coverage by LC-MS/MS without prefractionation. PMID:21586754
Protein multifunctionality: principles and mechanisms. PMID:21566747
Correct interpretation of comprehensive phosphorylation dynamics requires normalization by protein expression changes. PMID:21551504
Chromatin: constructing the big picture. PMID:21527910
Yeast zinc cluster proteins Dal81 and Uga3 cooperate by targeting common coactivators for transcriptional activation of γ-aminobutyrate responsive genes. PMID:21515579
Modular coherence of protein dynamics in yeast cell polarity system. PMID:21502521
A quantitative literature-curated gold standard for kinase-substrate pairs. PMID:21492431
Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast. PMID:21487389
A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. PMID:21454883
The CRIT framework for identifying cross patterns in systems biology and application to chemogenomics. PMID:21453526
Fluorescence molecule counting for single-molecule studies in crowded environment of living cells without and with broken ergodicity. PMID:21446904
The peroxin Pex34p functions with the Pex11 family of peroxisomal divisional proteins to regulate the peroxisome population in yeast. PMID:21441307
Trk2 transporter is a relevant player in K+ supply and plasma-membrane potential control in Saccharomyces cerevisiae. PMID:21424545
A genetic analysis of nitric oxide-mediated signaling during chronological aging in the yeast. PMID:21424154
The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets. PMID:21422231
The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase. PMID:21372173
A probabilistic model of nuclear import of proteins. PMID:21372083
Synthetic circuit identifies subpopulations with sustained memory of DNA damage. PMID:21363961
Improved techniques for endogenous epitope tagging and gene deletion in Toxoplasma gondii. PMID:21352857
The RSC chromatin remodelling enzyme has a unique role in directing the accurate positioning of nucleosomes. PMID:21343911
Mapping of protein- and chromatin-interactions at the nuclear lamina. PMID:21327087
The ins and outs of nuclear re-export of retrogradely transported tRNAs in Saccharomyces cerevisiae. PMID:21327067
Integrative identification of Arabidopsis mitochondrial proteome and its function exploitation through protein interaction network. PMID:21297957
The proteomics of quiescent and nonquiescent cell differentiation in yeast stationary-phase cultures. PMID:21289090
A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification. PMID:21285948
An FPT approach for predicting protein localization from yeast genomic data. PMID:21283516
Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids. PMID:21276210
Eukaryote-wide sequence analysis of mitochondrial β-barrel outer membrane proteins. PMID:21272379
Mne1 is a novel component of the mitochondrial splicing apparatus responsible for processing of a COX1 group I intron in yeast. PMID:21257754
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PMID:21249183
A novel mitochondrial outer membrane protein, MOMA-1, that affects cristae morphology in Caenorhabditis elegans. PMID:21248201
Discriminative motif finding for predicting protein subcellular localization. PMID:21233524
Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. PMID:21232131
Context-dependent transcriptional regulations between signal transduction pathways. PMID:21232126
Pun1p is a metal ion-inducible, calcineurin/Crz1p-regulated plasma membrane protein required for cell wall integrity. PMID:21223946
Identification of a Saccharomyces cerevisiae glucosidase that hydrolyzes flavonoid glucosides. PMID:21216897
Cdc48/p97 mediates UV-dependent turnover of RNA Pol II. PMID:21211725
Large-scale discovery and characterization of protein regulatory motifs in eukaryotes. PMID:21206902
Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. PMID:21197652
Improving the iMM904 S. cerevisiae metabolic model using essentiality and synthetic lethality data. PMID:21190580
Targeted protein depletion in Saccharomyces cerevisiae by activation of a bidirectional degron. PMID:21190544
Defining the budding yeast chromatin-associated interactome. PMID:21179020
Yeast homologues of three BLOC-1 subunits highlight KxDL proteins as conserved interactors of BLOC-1. PMID:21159114
The yeast Arf GTPase-activating protein Age1 is regulated by phospholipase D for post-Golgi vesicular transport. PMID:21135091
Differential regulation of transcription factors Stp1 and Stp2 in the Ssy1-Ptr3-Ssy5 amino acid sensing pathway. PMID:21127045
Simultaneous genome-wide inference of physical, genetic, regulatory, and functional pathway components. PMID:21124865
Effect of Saccharomyces cerevisiae ret1-1 mutation on glycosylation and localization of the secretome. PMID:21120625
A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae. PMID:21119626
Synonymous but not the same: the causes and consequences of codon bias. PMID:21102527
Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes. PMID:21098118
TESTLoc: protein subcellular localization prediction from EST data. PMID:21078192
DGK1-encoded diacylglycerol kinase activity is required for phospholipid synthesis during growth resumption from stationary phase in Saccharomyces cerevisiae. PMID:21071438
The exozyme model: a continuum of functionally distinct complexes. PMID:21068185
Parameter balancing in kinetic models of cell metabolism. PMID:21038890
Nuclear import by karyopherin-βs: recognition and inhibition. PMID:21029754
Zds2p regulates Swe1p-dependent polarized cell growth in Saccharomyces cerevisiae via a novel Cdc55p interaction domain. PMID:20980617
Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites. PMID:20974961
Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair. PMID:20967232
Discover protein complexes in protein-protein interaction networks using parametric local modularity. PMID:20958996
Rapamycin increases rDNA stability by enhancing association of Sir2 with rDNA in Saccharomyces cerevisiae. PMID:20947565
High-throughput screening of bacterial protein localization. PMID:20946849
iRefWeb: interactive analysis of consolidated protein interaction data and their supporting evidence. PMID:20940177
Context-dependent effects of asparagine glycosylation on Pin WW folding kinetics and thermodynamics. PMID:20936810
Phosphatidylserine is involved in the ferrichrome-induced plasma membrane trafficking of Arn1 in Saccharomyces cerevisiae. PMID:20923770
The DEAD-box RNA helicase-like Utp25 is an SSU processome component. PMID:20884785
Coxiella burnetii expresses a functional Δ24 sterol reductase. PMID:20870767
Condensed mitotic chromosome structure at nanometer resolution using PALM and EGFP- histones. PMID:20856676
Identification of Ypk1 as a novel selective substrate for nitrogen starvation-triggered proteolysis requiring autophagy system and endosomal sorting complex required for transport (ESCRT) machinery components. PMID:20855891
The forkhead transcription factor Hcm1 promotes mitochondrial biogenesis and stress resistance in yeast. PMID:20847055
A role for the dynamin-like protein Vps1 during endocytosis in yeast. PMID:20841380
Protein arginine methylation facilitates cotranscriptional recruitment of pre-mRNA splicing factors. PMID:20823272
Comparative analysis of nonaspanin protein sequences and expression studies in zebrafish. PMID:20820770
Reverse genetics in eukaryotes. PMID:20812916
tRNA biology charges to the front. PMID:20810645
Cooperation between the septins and the actomyosin ring and role of a cell-integrity pathway during cell division in fission yeast. PMID:20739711
Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes. PMID:20739463
Alpha-arrestins Aly1 and Aly2 regulate intracellular trafficking in response to nutrient signaling. PMID:20739461
Mass spectrometry-based proteomics in cell biology. PMID:20733050
Identification of novel filament-forming proteins in Saccharomyces cerevisiae and Drosophila melanogaster. PMID:20713603
Phosphatidylinositol 3-phosphate, an essential lipid in Plasmodium, localizes to the food vacuole membrane and the apicoplast. PMID:20709789
Vacuolar cation/H+ antiporters of Saccharomyces cerevisiae. PMID:20709757
Structural role of the Vps4-Vta1 interface in ESCRT-III recycling. PMID:20696398
Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay. PMID:20694142
The mitochondrial proteome and human disease. PMID:20690818
Thioredoxin regulates multiple hydrogen peroxide-induced signaling pathways in Candida albicans. PMID:20679492
Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells. PMID:20671182
Tinkering evolution of post-transcriptional RNA regulons: puf3p in fungi as an example. PMID:20661438
Asymmetrically inherited multidrug resistance transporters are recessive determinants in cellular replicative ageing. PMID:20657593
Inferring modules from human protein interactome classes. PMID:20653930
A novel mechanism for SUMO system control: regulated Ulp1 nucleolar sequestration. PMID:20647537
Combining machine learning and homology-based approaches to accurately predict subcellular localization in Arabidopsis. PMID:20647376
Characterization of substrates that have a differential effect on Saccharomyces cerevisiae protein kinase A holoenzyme activation. PMID:20639203
It's the machine that matters: Predicting gene function and phenotype from protein networks. PMID:20637909
Automated Proteome-Wide Determination of Subcellular Location Using High Throughput Microscopy. PMID:20622996
High-throughput profiling of amino acids in strains of the Saccharomyces cerevisiae deletion collection. PMID:20610602
Computational prediction and experimental assessment of secreted/surface proteins from Mycobacterium tuberculosis H37Rv. PMID:20585611
Sequential counteracting kinases restrict an asymmetric gene expression program to early G1. PMID:20573982
The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage. PMID:20566477
Toward understanding the informatics and statistical aspects of micro-RNA profiling. PMID:20560041
The subcellular localization of yeast glycogen synthase is dependent upon glycogen content. PMID:20555403
Structural characterization of the Get4/Get5 complex and its interaction with Get3. PMID:20554915
The budding yeast nucleus. PMID:20554704
The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation. PMID:20538609
Measurement of single-cell dynamics. PMID:20535203
The TOR pathway modulates the structure of cell walls in Arabidopsis. PMID:20530756
Quantifying the distribution of probes between subcellular locations using unsupervised pattern unmixing. PMID:20529939
A novel role of the yeast CaaX protease Ste24 in chitin synthesis. PMID:20505074
Mdm36 is a mitochondrial fission-promoting protein in Saccharomyces cerevisiae. PMID:20505073
Scyl1 facilitates nuclear tRNA export in mammalian cells by acting at the nuclear pore complex. PMID:20505071
Nucleolus as an oxidative stress sensor in the yeast Saccharomyces cerevisiae. PMID:20500990
Pom33, a novel transmembrane nucleoporin required for proper nuclear pore complex distribution. PMID:20498018
The Yeast Resource Center Public Image Repository: A large database of fluorescence microscopy images. PMID:20482811
Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase. PMID:20482385
Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe. PMID:20473289
Evaluation of methods for detection of fluorescence labeled subcellular objects in microscope images. PMID:20465797
Decoding signalling networks by mass spectrometry-based proteomics. PMID:20461098
A general lack of compensation for gene dosage in yeast. PMID:20461075
Global analysis of the rat and human platelet proteome - the molecular blueprint for illustrating multi-functional platelets and cross-species function evolution. PMID:20443191
The activity of yeast Hog1 MAPK is required during endoplasmic reticulum stress induced by tunicamycin exposure. PMID:20430884
PhosphoGRID: a database of experimentally verified in vivo protein phosphorylation sites from the budding yeast Saccharomyces cerevisiae. PMID:20428315
Homocysteine methyltransferases Mht1 and Sam4 prevent the accumulation of age-damaged (R,S)-AdoMet in the yeast Saccharomyces cerevisiae. PMID:20421295
DNA sequence encoded repression of rRNA gene transcription in chromatin. PMID:20421213
Regulation of glycogen metabolism in yeast and bacteria. PMID:20412306
BiP availability distinguishes states of homeostasis and stress in the endoplasmic reticulum of living cells. PMID:20410136
Yet1p and Yet3p, the yeast homologs of BAP29 and BAP31, interact with the endoplasmic reticulum translocation apparatus and are required for inositol prototrophy. PMID:20378542
Localization to, and effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on stress granules in Saccharomyces cerevisiae. PMID:20368989
A ribosome-anchored chaperone network that facilitates eukaryotic ribosome biogenesis. PMID:20368619
Need-based up-regulation of protein levels in response to deletion of their duplicate genes. PMID:20361019
Systematic analysis of human protein complexes identifies chromosome segregation proteins. PMID:20360068
Marker fusion tagging, a new method for production of chromosomally encoded fusion proteins. PMID:20348390
Protein subcellular relocalization in the evolution of yeast singleton and duplicate genes. PMID:20333190
Triacylglycerol homeostasis: insights from yeast. PMID:20231294
5' to 3' mRNA decay factors colocalize with Ty1 gag and human APOBEC3G and promote Ty1 retrotransposition. PMID:20219921
Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control. PMID:20212121
Tubulin chaperone E binds microtubules and proteasomes and protects against misfolded protein stress. PMID:20204449
Transcriptional regulation of respiration in yeast metabolizing differently repressive carbon substrates. PMID:20167065
Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. PMID:20159853
Computational approaches for detecting protein complexes from protein interaction networks: a survey. PMID:20158874
The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1. PMID:20157544
The trypanosome Pumilio-domain protein PUF7 associates with a nuclear cyclophilin and is involved in ribosomal RNA maturation. PMID:20153321
Activity-based proteomics of enzyme superfamilies: serine hydrolases as a case study. PMID:20147750
Protein subcellular localization profiling of breast cancer cells by dissociable antibody microarray staining. PMID:20127686
Peroxisome diversity and evolution. PMID:20124343
DMR1 (CCM1/YGR150C) of Saccharomyces cerevisiae encodes an RNA-binding protein from the pentatricopeptide repeat family required for the maintenance of the mitochondrial 15S ribosomal RNA. PMID:20124025
Value of using multiple proteases for large-scale mass spectrometry-based proteomics. PMID:20113005
A generative model of microtubule distributions, and indirect estimation of its parameters from fluorescence microscopy images. PMID:20104579
Yeast exonuclease 5 is essential for mitochondrial genome maintenance. PMID:20086101
A protocol for generating a high-quality genome-scale metabolic reconstruction. PMID:20057383
A unique role for the host ESCRT proteins in replication of Tomato bushy stunt virus. PMID:20041173
Regulation of tRNA bidirectional nuclear-cytoplasmic trafficking in Saccharomyces cerevisiae. PMID:20032305
Expanding the definition of the classical bipartite nuclear localization signal. PMID:20028483
Dynamic changes in the subcellular distribution of Gpd1p in response to cell stress. PMID:20026609
Compartment-specific synthesis of phosphatidylethanolamine is required for normal heavy metal resistance. PMID:20016005
Interaction between Sdo1p and Btn1p in the Saccharomyces cerevisiae model for Batten disease. PMID:20015955
The final step in 5.8S rRNA processing is cytoplasmic in Saccharomyces cerevisiae. PMID:20008552
Iron regulation through the back door: iron-dependent metabolite levels contribute to transcriptional adaptation to iron deprivation in Saccharomyces cerevisiae. PMID:20008079
Rrp17p is a eukaryotic exonuclease required for 5' end processing of Pre-60S ribosomal RNA. PMID:20005841
Towards accurate imputation of quantitative genetic interactions. PMID:20003301
Identification of positive regulators of the yeast fps1 glycerol channel. PMID:19956799
The KM-Algorithm Identifies Regulated Genes in Time Series Expression Data. PMID:19956417
Roles of Pichia pastoris Uvrag in vacuolar protein sorting and the phosphatidylinositol 3-kinase complex in phagophore elongation in autophagy pathways. PMID:19946209
CYSTM, a novel cysteine-rich transmembrane module with a role in stress tolerance across eukaryotes. PMID:19933165
Cellular dynamics of tRNAs and their genes. PMID:19931532
Systems biology from a yeast omics perspective. PMID:19903479
Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation. PMID:19902144
Reverse engineering a signaling network using alternative inputs. PMID:19898612
Rad4 regulates protein turnover at a postubiquitylation step. PMID:19889839
Hsp90 nuclear accumulation in quiescence is linked to chaperone function and spore development in yeast. PMID:19889838
Comparative analyses of time-course gene expression profiles of the long-lived sch9Delta mutant. PMID:19880387
13C-metabolic flux ratio and novel carbon path analyses confirmed that Trichoderma reesei uses primarily the respirative pathway also on the preferred carbon source glucose. PMID:19874611
Interlaboratory study characterizing a yeast performance standard for benchmarking LC-MS platform performance. PMID:19858499
The rubella virus capsid protein inhibits mitochondrial import. PMID:19846524
Interaction of yeast eIF4G with spliceosome components: implications in pre-mRNA processing events. PMID:19838078
Tracking lineages of single cells in lines using a microfluidic device. PMID:19826080
Dse1 may control cross talk between the pheromone and filamentation pathways in yeast. PMID:19820940
Utp9p facilitates Msn5p-mediated nuclear reexport of retrograded tRNAs in Saccharomyces cerevisiae. PMID:19812255
Rational extension of the ribosome biogenesis pathway using network-guided genetics. PMID:19806183
Biogenesis of glutaminyl-mt tRNAGln in human mitochondria. PMID:19805282
The arrestin fold: variations on a theme. PMID:19794886
A genomic screen for yeast mutants defective in selective mitochondria autophagy. PMID:19793921
Role and dynamics of the ribosomal protein P0 and its related trans-acting factor Mrt4 during ribosome assembly in Saccharomyces cerevisiae. PMID:19789271
Development of a high-throughput method for the systematic identification of human proteins nuclear translocation potential. PMID:19772597
Genetically encoded biosensors based on engineered fluorescent proteins. PMID:19771330
Towards the prediction of essential genes by integration of network topology, cellular localization and biological process information. PMID:19758426
Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes. PMID:19756047
Efficient framework for automated classification of subcellular patterns in budding yeast. PMID:19753630
Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. PMID:19751518
Mitochondrial function is an inducible determinant of osmotic stress adaptation in yeast. PMID:19720830
Sugar metabolism, redox balance and oxidative stress response in the respiratory yeast Kluyveromyces lactis. PMID:19715615
Cotranslational assembly of the yeast SET1C histone methyltransferase complex. PMID:19713935
Evidence for a role of FEN1 in maintaining mitochondrial DNA integrity. PMID:19699691
Demonstrated and inferred metabolism associated with cytosolic lipid droplets. PMID:19696439
Enhancer of decapping proteins 1 and 2 are important for translation during heat stress in Saccharomyces cerevisiae. PMID:19682251
m-TAG: a PCR-based genomic integration method to visualize the localization of specific endogenous mRNAs in vivo in yeast. PMID:19680241
Multisite phosphorylation of the guanine nucleotide exchange factor Cdc24 during yeast cell polarization. PMID:19668330
Proteome-wide prediction of acetylation substrates. PMID:19666589
Cell-type-specific isolation of ribosome-associated mRNA from complex tissues. PMID:19666516
Cardiolipin molecular species with shorter acyl chains accumulate in Saccharomyces cerevisiae mutants lacking the acyl coenzyme A-binding protein Acb1p: new insights into acyl chain remodeling of cardiolipin. PMID:19656950
Repression of sulfate assimilation is an adaptive response of yeast to the oxidative stress of zinc deficiency. PMID:19656949
Reciprocal efficiency of RNQ1 and polyglutamine detoxification in the cytosol and nucleus. PMID:19656852
Multi-level learning: improving the prediction of protein, domain and residue interactions by allowing information flow between levels. PMID:19656385
Multiple aspects of ATP-dependent nucleosome translocation by RSC and Mi-2 are directed by the underlying DNA sequence. PMID:19626125
Acetyl-coenzyme A synthetase 2 is a nuclear protein required for replicative longevity in Saccharomyces cerevisiae. PMID:19618123
Calculation of the relative metastabilities of proteins in subcellular compartments of Saccharomyces cerevisiae. PMID:19615086
Mechanism and a peptide motif for targeting peripheral proteins to the yeast inner nuclear membrane. PMID:19602197
Defects in tRNA modification associated with neurological and developmental dysfunctions in Caenorhabditis elegans elongator mutants. PMID:19593383
Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein function. PMID:19581443
Qri7/OSGEPL, the mitochondrial version of the universal Kae1/YgjD protein, is essential for mitochondrial genome maintenance. PMID:19578062
Functional annotations for the Saccharomyces cerevisiae genome: the knowns and the known unknowns. PMID:19577472
Gga2 mediates sequential ubiquitin-independent and ubiquitin-dependent steps in the trafficking of ARN1 from the trans-Golgi network to the vacuole. PMID:19574226
Lipoic acid synthesis and attachment in yeast mitochondria. PMID:19570983
Fueling transcriptional silencing with Gas1. PMID:19567837
A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling. PMID:19564405
Ccm1p/Ygr150cp, a pentatricopeptide repeat protein, is essential to remove the fourth intron of both COB and COX1 pre-mRNAs in Saccharomyces cerevisiae. PMID:19562342
Mutations in the Saccharomyces cerevisiae kinase Cbk1p lead to a fertility defect that can be suppressed by the absence of Brr1p or Mpt5p (Puf5p), proteins involved in RNA metabolism. PMID:19546315
The glucanosyltransferase Gas1 functions in transcriptional silencing. PMID:19541632
A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex. PMID:19521502
Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs. PMID:19520826
Regulators of yeast endocytosis identified by systematic quantitative analysis. PMID:19506040
Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria. PMID:19506038
Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation. PMID:19502427
Protein interaction platforms: visualization of interacting proteins in yeast. PMID:19483691
Network-based prediction of metabolic enzymes' subcellular localization. PMID:19477995
Biases in Drosophila melanogaster protein trap screens. PMID:19476619
Regulation of cell polarity through phosphorylation of Bni4 by Pho85 G1 cyclin-dependent kinases in Saccharomyces cerevisiae. PMID:19458192
Systems level modeling of the cell cycle using budding yeast. PMID:19455254
Conformational flexibility and molecular interactions of an archaeal homologue of the Shwachman-Bodian-Diamond syndrome protein. PMID:19454024
A targeted bypass screen identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for stable U1 snRNP/Pre-mRNA interaction. PMID:19451230
Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1. PMID:19448108
Structure and function of Vps15 in the endosomal G protein signaling pathway. PMID:19445518
Functional redundancy of yeast proteins Reh1 and Rei1 in cytoplasmic 60S subunit maturation. PMID:19433447
Writing DNA with GenoCAD. PMID:19429897
Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS. PMID:19417106
Molecular recognition of the palmitoylation substrate Vac8 by its palmitoyltransferase Pfa3. PMID:19416974
Quantitative genome-scale analysis of protein localization in an asymmetric bacterium. PMID:19416866
New insights into {gamma}-aminobutyric acid catabolism: Evidence for {gamma}-hydroxybutyric acid and polyhydroxybutyrate synthesis in Saccharomyces cerevisiae. PMID:19411412
Molecular tools for cell and systems biology. PMID:19404424
Efficient protein depletion by genetically controlled deprotection of a dormant N-degron. PMID:19401679
Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. PMID:19387489
Multicopy suppressor analysis of thermosensitive YIP1 alleles implicates GOT1 in transport from the ER. PMID:19383723
New fluorescence microscopy methods for microbiology: sharper, faster, and quantitative. PMID:19356974
Endoplasmic reticulum-associated secretory proteins Sec20p, Sec39p, and Dsl1p are involved in peroxisome biogenesis. PMID:19346454
Cd2+, Mn2+, Ni2+ and Se2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2. PMID:19345671
Reconstructing the ubiquitin network: cross-talk with other systems and identification of novel functions. PMID:19331687
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. PMID:19325107
Detection of protein-protein interactions through vesicle targeting. PMID:19307607
Statistical and visual differentiation of subcellular imaging. PMID:19302715
Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PMID:19300474
The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA. PMID:19287007
Lessons from fungal F-box proteins. PMID:19286981
Linking phospholipid flippases to vesicle-mediated protein transport. PMID:19286470
ER membrane-bending proteins are necessary for de novo nuclear pore formation. PMID:19273614
A mechanism for chromosome segregation sensing by the NoCut checkpoint. PMID:19270692
Unifying fluorescence microscopy and mass spectrometry for studying protein complexes in cells. PMID:19269952
Deregulation of DSE1 gene expression results in aberrant budding within the birth scar and cell wall integrity pathway activation in Saccharomyces cerevisiae. PMID:19252124
Hydrolase regulates NAD+ metabolites and modulates cellular redox. PMID:19251690
Exploring the roles of noise in the eukaryotic cell cycle. PMID:19246388
Prion proteostasis: Hsp104 meets its supporting cast. PMID:19242125
Environment-specific combinatorial cis-regulation in synthetic promoters. PMID:19225457
Interdependent nucleocytoplasmic trafficking and interactions of Dis3 with Rrp6, the core exosome and importin-alpha3. PMID:19220816
p21-activated kinases Cla4 and Ste20 regulate vacuole inheritance in Saccharomyces cerevisiae. PMID:19218422
MitoMiner, an integrated database for the storage and analysis of mitochondrial proteomics data. PMID:19208617
A method to improve protein subcellular localization prediction by integrating various biological data sources. PMID:19208145
Methionine sulphoxide reductases protect iron-sulphur clusters from oxidative inactivation in yeast. PMID:19202110
Requirement of the Saccharomyces cerevisiae APN1 gene for the repair of mitochondrial DNA alkylation damage. PMID:19197988
A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. PMID:19194512
Functional characterization of ribosomal protein L15 from Saccharomyces cerevisiae. PMID:19184027
Suppression of a DNA polymerase delta mutation by the absence of the high mobility group protein Hmo1 in Saccharomyces cerevisiae. PMID:19184026
Learning a prior on regulatory potential from eQTL data. PMID:19180192
A complex-based reconstruction of the Saccharomyces cerevisiae interactome. PMID:19176519
Characterization of proteins associated with polyglutamine aggregates: a novel approach towards isolation of aggregates from protein conformation disorders. PMID:19164926
The WASP homologue Las17 activates the novel actin-regulatory activity of Ysc84 to promote endocytosis in yeast. PMID:19158382
A key role for heat shock protein 70 in the localization and insertion of tombusvirus replication proteins to intracellular membranes. PMID:19153242
Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions. PMID:19151091
A novel approach for organelle-specific DNA damage targeting reveals different susceptibility of mitochondrial DNA to the anticancer drugs camptothecin and topotecan. PMID:19151088
Reengineering ribosome export. PMID:19144820
TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain. PMID:19144819
Live cell fluorescence microscopy to study microbial pathogenesis. PMID:19134122
In silico evidence for functional specialization after genome duplication in yeast. PMID:19133069
The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome. PMID:19129231
Phospholipid transfer protein Sec14 is required for trafficking from endosomes and regulates distinct trans-Golgi export pathways. PMID:19129178
Efficiency of complex production in changing environment. PMID:19128449
Reconstruction of biochemical networks in microorganisms. PMID:19116616
PTC1 is required for vacuole inheritance and promotes the association of the myosin-V vacuole-specific receptor complex. PMID:19116310
A mutant plasma membrane protein is stabilized upon loss of Yvh1, a novel ribosome assembly factor. PMID:19114459
Analyzing P-bodies in Saccharomyces cerevisiae. PMID:19111192
Evolution of organelle-associated protein profiling. PMID:19110081
The anaphase-promoting complex promotes actomyosin-ring disassembly during cytokinesis in yeast. PMID:19109423
A novel proteomics approach for the discovery of chromatin-associated protein networks. PMID:19106085
Sec6p anchors the assembled exocyst complex at sites of secretion. PMID:19073882
The chemotherapeutic agents XK469 (2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid) and SH80 (2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid) inhibit cytokinesis and promote polyploidy and induce senescence. PMID:19066341
Plasma membrane microdomains regulate turnover of transport proteins in yeast. PMID:19064668
Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening. PMID:19061901
A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. PMID:19061648
A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast. PMID:19061647
Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae. PMID:19060182
Systematic definition of protein constituents along the major polarization axis reveals an adaptive reuse of the polarization machinery in pheromone-treated budding yeast. PMID:19053807
Kex2 protease converts the endoplasmic reticulum alpha1,2-mannosidase of Candida albicans into a soluble cytosolic form. PMID:19047746
The Alpha Project: a model system for systems biology research. PMID:19045818
Profiling synaptic proteins identifies regulators of insulin secretion and lifespan. PMID:19043554
Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. PMID:19040720
A label free quantitative proteomic analysis of the Saccharomyces cerevisiae nucleus. PMID:19038371
Training set expansion: an approach to improving the reconstruction of biological networks from limited and uneven reliable interactions. PMID:19015141
Annotating proteins with generalized functional linkages. PMID:19004787
Real-time luminescence monitoring of cell-cycle and respiratory oscillations in yeast. PMID:19004762
The classical nuclear localization signal receptor, importin-alpha, is required for efficient transition through the G1/S stage of the cell cycle in Saccharomyces cerevisiae. PMID:18984568
P bodies promote stress granule assembly in Saccharomyces cerevisiae. PMID:18981231
Transcriptional activation in yeast in response to copper deficiency involves copper-zinc superoxide dismutase. PMID:18977757
Technical considerations in using DNA microarrays to define regulons. PMID:18955146
Activity motifs reveal principles of timing in transcriptional control of the yeast metabolic network. PMID:18953355
Localization and interaction of the proteins constituting the GAL genetic switch in Saccharomyces cerevisiae. PMID:18952899
The anaphase promoting complex targeting subunit Ama1 links meiotic exit to cytokinesis during sporulation in Saccharomyces cerevisiae. PMID:18946082
Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p. PMID:18940861
An incremental approach to automated protein localisation. PMID:18937856
Identification of mitochondrial disease genes through integrative analysis of multiple datasets. PMID:18930150
Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex. PMID:18843051
Dif1 controls subcellular localization of ribonucleotide reductase by mediating nuclear import of the R2 subunit. PMID:18838542
Protein networks markedly improve prediction of subcellular localization in multiple eukaryotic species. PMID:18836191
Frequency-modulated nuclear localization bursts coordinate gene regulation. PMID:18818649
The structure of YqeH. An AtNOS1/AtNOA1 ortholog that couples GTP hydrolysis to molecular recognition. PMID:18801747
The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans. PMID:18799621
The yeast lysosome-like vacuole: endpoint and crossroads. PMID:18786576
In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase. PMID:18782763
MitoP2: an integrative tool for the analysis of the mitochondrial proteome. PMID:18780189
Intersection of RNA processing and the type II fatty acid synthesis pathway in yeast mitochondria. PMID:18779316
Photoactivatable GFP tagging cassettes for protein-tracking studies in the budding yeast Saccharomyces cerevisiae. PMID:18727145
The GET complex mediates insertion of tail-anchored proteins into the ER membrane. PMID:18724936
Some assembly required: dedicated chaperones in eukaryotic proteasome biogenesis. PMID:18713001
Similarities between UDP-glucose and adenine nucleotide release in yeast: involvement of the secretory pathway. PMID:18693752
The yeast spore wall enables spores to survive passage through the digestive tract of Drosophila. PMID:18682732
Constraints imposed by non-functional protein-protein interactions on gene expression and proteome size. PMID:18682700
Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae. PMID:18675371
Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains. PMID:18629296
Identification and comparative analysis of the peptidyl-prolyl cis/trans isomerase repertoires of H. sapiens, D. melanogaster, C. elegans, S. cerevisiae and Sz. pombe. PMID:18629211
Investigation into the use of C- and N-terminal GFP fusion proteins for subcellular localization studies using reverse transfection microarrays. PMID:18629169
The Yeast Saccharomyces cerevisiae: a versatile model system for the identification and characterization of bacterial virulence proteins. PMID:18621006
Mechanisms of cell cycle control revealed by a systematic and quantitative overexpression screen in S. cerevisiae. PMID:18617996
Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies. PMID:18617993
A mitochondrial protein compendium elucidates complex I disease biology. PMID:18614015
Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. PMID:18613951
Predicting gene function in a hierarchical context with an ensemble of classifiers. PMID:18613947
Polarized growth in the absence of F-actin in Saccharomyces cerevisiae exiting quiescence. PMID:18596916
A proteomics analysis of yeast Mot1p protein-protein associations: insights into mechanism. PMID:18596064
Assessing the functional structure of genomic data. PMID:18586732
The PRA1 gene family in Arabidopsis. PMID:18583532
Mass spectrometry analysis of proteome-wide proteolytic post-translational degradation of proteins. PMID:18578501
A distinct endosomal Ca2+/Mn2+ pump affects root growth through the secretory process. PMID:18567829
Different domains of the UBL-UBA ubiquitin receptor, Ddi1/Vsm1, are involved in its multiple cellular roles. PMID:18562697
Aspergillus nidulans ArfB plays a role in endocytosis and polarized growth. PMID:18539885
DOA1/UFD3 plays a role in sorting ubiquitinated membrane proteins into multivesicular bodies. PMID:18508771
Revisiting the Saccharomyces cerevisiae predicted ORFeome. PMID:18502943
Sequence-based prediction of protein-protein interactions by means of codon usage. PMID:18501006
Intrinsic and cyclin-dependent kinase-dependent control of spindle pole body duplication in budding yeast. PMID:18480404
Dual targeted mitochondrial proteins are characterized by lower MTS parameters and total net charge. PMID:18478128
Identification of a novel N-terminal hydrophobic sequence that targets proteins to lipid droplets. PMID:18477614
Enhancing drug accumulation in Saccharomyces cerevisiae by repression of pleiotropic drug resistance genes with chimeric transcription repressors. PMID:18469141
GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae. PMID:18451787
BAC to the future: functional genomics in mammals. PMID:18446155
A Mep2-dependent transcriptional profile links permease function to gene expression during pseudohyphal growth in Saccharomyces cerevisiae. PMID:18434596
Yeast Pgc1p (YPL206c) controls the amount of phosphatidylglycerol via a phospholipase C-type degradation mechanism. PMID:18434318
SAM domain-based protein oligomerization observed by live-cell fluorescence fluctuation spectroscopy. PMID:18431466
The Saccharomyces cerevisiae actin cytoskeletal component Bsp1p has an auxiliary role in actomyosin ring function and in the maintenance of bud-neck structure. PMID:18430924
Genome-wide analysis of signaling networks regulating fatty acid-induced gene expression and organelle biogenesis. PMID:18426976
Predicting co-complexed protein pairs from heterogeneous data. PMID:18421371
Analysis of the yeast kinome reveals a network of regulated protein localization during filamentous growth. PMID:18417610
A map of human protein interactions derived from co-expression of human mRNAs and their orthologs. PMID:18414481
Chaperone ligand-discrimination by the TPR-domain protein Tah1. PMID:18412542
Golgi localization of glycosyltransferases requires a Vps74p oligomer. PMID:18410729
Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif. PMID:18410493
Rtr1 is the Saccharomyces cerevisiae homolog of a novel family of RNA polymerase II-binding proteins. PMID:18408053
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. PMID:18391959
Chloride homeostasis in Saccharomyces cerevisiae: high affinity influx, V-ATPase-dependent sequestration, and identification of a candidate Cl- sensor. PMID:18378800
A BBP-Mud2p heterodimer mediates branchpoint recognition and influences splicing substrate abundance in budding yeast. PMID:18375978
Predicting cancer involvement of genes from heterogeneous data. PMID:18371197
Ear1p and Ssh4p are new adaptors of the ubiquitin ligase Rsp5p for cargo ubiquitylation and sorting at multivesicular bodies. PMID:18367543
A PY-NLS nuclear targeting signal is required for nuclear localization and function of the Saccharomyces cerevisiae mRNA-binding protein Hrp1. PMID:18343812
Functional diversification of duplicate genes through subcellular adaptation of encoded proteins. PMID:18336717
Bud23 methylates G1575 of 18S rRNA and is required for efficient nuclear export of pre-40S subunits. PMID:18332120
Cdc1p is an endoplasmic reticulum-localized putative lipid phosphatase that affects Golgi inheritance and actin polarization by activating Ca2+ signaling. PMID:18332110
Proteomic view of mitochondrial function. PMID:18331620
Heat shock response relieves ER stress. PMID:18323774
Unconventional genomic architecture in the budding yeast saccharomyces cerevisiae masks the nested antisense gene NAG1. PMID:18310357
DBMLoc: a Database of proteins with multiple subcellular localizations. PMID:18304364
Fuzzy association rules for biological data analysis: a case study on yeast. PMID:18284669
Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis. PMID:18281282
The peroxisome: still a mysterious organelle. PMID:18274771
Proteome-wide identification of proteins and their modifications with decreased ambiguities and improved false discovery rates using unique sequence tags. PMID:18271604
Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis. PMID:18270585
A new pairwise kernel for biological network inference with support vector machines. PMID:18269702
Visualizing and clustering high throughput sub-cellular localization imaging. PMID:18241353
A novel immunodetection screen for vacuolar defects identifies a unique allele of VPS35 in S. cerevisiae. PMID:18224426
Global analysis of yeast endosomal transport identifies the vps55/68 sorting complex. PMID:18216282
A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells. PMID:18213377
Towards defining the nuclear proteome. PMID:18211718
Yeast Arf3p modulates plasma membrane PtdIns(4,5)P2 levels to facilitate endocytosis. PMID:18208507
The utility of affinity-tags for detection of a streptococcal protein from a variety of streptococcal species. PMID:18201786
Dissecting the ER-associated degradation of a misfolded polytopic membrane protein. PMID:18191224
Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae. PMID:18179719
Ypi1, a positive regulator of nuclear protein phosphatase type 1 activity in Saccharomyces cerevisiae. PMID:18172024
Evolutionarily conserved gene family important for fat storage. PMID:18160536
Counting kinetochore protein numbers in budding yeast using genetically encoded fluorescent proteins. PMID:18155462
Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. PMID:18086879
Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PMID:18085829
Intracellular localization map of human herpesvirus 8 proteins. PMID:18077714
Localization of telomeres and telomere-associated proteins in telomerase-negative Saccharomyces cerevisiae. PMID:18075778
Novel roles for selected genes in meiotic DNA processing. PMID:18069899
The evolutionary conserved BER1 gene is involved in microtubule stability in yeast. PMID:18064466
In vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modification. PMID:18046568
Using protein complexes to predict phenotypic effects of gene mutation. PMID:18042286
Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting. PMID:18032584
Ist1 regulates Vps4 localization and assembly. PMID:18032582
Hubs with network motifs organize modularity dynamically in the protein-protein interaction network of yeast. PMID:18030341
A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration. PMID:18022565
Sus1, Sac3, and Thp1 mediate post-transcriptional tethering of active genes to the nuclear rim as well as to non-nascent mRNP. PMID:18003937
Spore germination in Saccharomyces cerevisiae: global gene expression patterns and cell cycle landmarks. PMID:17999778
Immobility, inheritance and plasticity of shape of the yeast nucleus. PMID:17996101
Examining protein protein interactions using endogenously tagged yeast arrays: the cross-and-capture system. PMID:17989249
Identification of yeast proteins necessary for cell-surface function of a potassium channel. PMID:17989219
The limits of subfunctionalization. PMID:17988397
Gene Ontology annotations at SGD: new data sources and annotation methods. PMID:17982175
Optimized protein extraction for quantitative proteomics of yeasts. PMID:17957260
Lipid phosphate phosphatases from Saccharomyces cerevisiae. PMID:17954255
Inositol polyphosphates: a new frontier for regulating gene expression. PMID:17943301
Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases. PMID:17938163
An improved, bias-reduced probabilistic functional gene network of baker's yeast, Saccharomyces cerevisiae. PMID:17912365
Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104p. PMID:17908928
Alternative modes of organellar segregation during sporulation in Saccharomyces cerevisiae. PMID:17905927
DNA sequence- and conformation-directed positioning of nucleosomes by chromatin-remodeling complexes. PMID:17893337
A chemogenomic screening of sulfanilamide-hypersensitive Saccharomyces cerevisiae mutants uncovers ABZ2, the gene encoding a fungal aminodeoxychorismate lyase. PMID:17873082
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks. PMID:17854489
Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast. PMID:17853895
Global phenotype screening and transcript analysis outlines the inhibitory mode(s) of action of two amphibian-derived, alpha-helical, cationic peptides on Saccharomyces cerevisiae. PMID:17846143
Condensin function at centromere chromatin facilitates proper kinetochore tension and ensures correct mitotic segregation of sister chromatids. PMID:17825050
Pho91 Is a vacuolar phosphate transporter that regulates phosphate and polyphosphate metabolism in Saccharomyces cerevisiae. PMID:17804816
The yeast integral membrane protein Apq12 potentially links membrane dynamics to assembly of nuclear pore complexes. PMID:17724120
Trafficking of siderophore transporters in Saccharomyces cerevisiae and intracellular fate of ferrioxamine B conjugates. PMID:17714436
High-throughput fluorescent-based optimization of eukaryotic membrane protein overexpression and purification in Saccharomyces cerevisiae. PMID:17709746
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory. PMID:17697349
A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions. PMID:17696614
Network motif analysis of a multi-mode genetic-interaction network. PMID:17683534
Increased glycolytic flux as an outcome of whole-genome duplication in yeast. PMID:17667951
A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae. PMID:17667949
Electron paramagnetic resonance and Mössbauer spectroscopy of intact mitochondria from respiring Saccharomyces cerevisiae. PMID:17665226
A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. PMID:17660569
Screen for ISG15-crossreactive deubiquitinases. PMID:17653289
The Hsp40 chaperone Jjj1 is required for the nucleo-cytoplasmic recycling of preribosomal factors in Saccharomyces cerevisiae. PMID:17652132
Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1. PMID:17646390
Genetic analysis of SUMOylation in Arabidopsis: conjugation of SUMO1 and SUMO2 to nuclear proteins is essential. PMID:17644626
Utp8p is a nucleolar tRNA-binding protein that forms a complex with components of the nuclear tRNA export machinery in Saccharomyces cerevisiae. PMID:17634288
A protein interaction map of the mitotic spindle. PMID:17634282
Interactions between brome mosaic virus RNAs and cytoplasmic processing bodies. PMID:17609284
Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. PMID:17608707
The potential of high-content high-throughput microscopy in drug discovery. PMID:17603554
CVAK104 is a novel regulator of clathrin-mediated SNARE sorting. PMID:17587408
Sir2p-dependent protein segregation gives rise to a superior reactive oxygen species management in the progeny of Saccharomyces cerevisiae. PMID:17581878
YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation. PMID:17576801
Transcriptional responses to fatty acid are coordinated by combinatorial control. PMID:17551510
In search of the biological significance of modular structures in protein networks. PMID:17542644
Practical and theoretical advances in predicting the function of a protein by its phylogenetic distribution. PMID:17535793
Unequal evolutionary conservation of human protein interactions in interologous networks. PMID:17535438
The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA. PMID:17531814
Interaction of the endocytic scaffold protein Pan1 with the type I myosins contributes to the late stages of endocytosis. PMID:17522383
WoLF PSORT: protein localization predictor. PMID:17517783
Probing the membrane environment of the TOR kinases reveals functional interactions between TORC1, actin, and membrane trafficking in Saccharomyces cerevisiae. PMID:17507646
Biogenesis and function of multivesicular bodies. PMID:17506697
Inferring biological networks with output kernel trees. PMID:17493253
Coiled coil structures and transcription: an analysis of the S. cerevisiae coilome. PMID:17476531
Accumulation of polyadenylated mRNA, Pab1p, eIF4E, and eIF4G with P-bodies in Saccharomyces cerevisiae. PMID:17475768
Maturation of the mammalian secretome. PMID:17472737
In vivo functional characterization of the Saccharomyces cerevisiae 60S biogenesis GTPase Nog1. PMID:17443350
Network of general and specialty J protein chaperones of the yeast cytosol. PMID:17438278
Why are there still over 1000 uncharacterized yeast genes? PMID:17435240
Yct1p, a novel, high-affinity, cysteine-specific transporter from the yeast Saccharomyces cerevisiae. PMID:17435223
Inorganic phosphate deprivation causes tRNA nuclear accumulation via retrograde transport in Saccharomyces cerevisiae. PMID:17409072
A large number of novel coding small open reading frames in the intergenic regions of the Arabidopsis thaliana genome are transcribed and/or under purifying selection. PMID:17395691
Fast automated cell phenotype image classification. PMID:17394669
On the evolutionary origin of aging. PMID:17376147
Regulation of the stringent response is the essential function of the conserved bacterial G protein CgtA in Vibrio cholerae. PMID:17360576
Network-based prediction of protein function. PMID:17353930
Central roles of small GTPases in the development of cell polarity in yeast and beyond. PMID:17347519
Correlation between transcript profiles and fitness of deletion mutants in anaerobic chemostat cultures of Saccharomyces cerevisiae. PMID:17322208
Expanding the mitochondrial interactome. PMID:17319976
YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA. PMID:17317628
The p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors. PMID:17308036
Effect of 21 different nitrogen sources on global gene expression in the yeast Saccharomyces cerevisiae. PMID:17308034
Large-scale automated analysis of location patterns in randomly tagged 3T3 cells. PMID:17285363
Identification of Rkr1, a nuclear RING domain protein with functional connections to chromatin modification in Saccharomyces cerevisiae. PMID:17283062
Visualizing the proteome of Escherichia coli: an efficient and versatile method for labeling chromosomal coding DNA sequences (CDSs) with fluorescent protein genes. PMID:17272300
The specialized cytosolic J-protein, Jjj1, functions in 60S ribosomal subunit biogenesis. PMID:17242366
Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturation. PMID:17242065
Glucose-responsive regulators of gene expression in Saccharomyces cerevisiae function at the nuclear periphery via a reverse recruitment mechanism. PMID:17237508
Structural insight into the ESCRT-I/-II link and its role in MVB trafficking. PMID:17215868
Ashbya Genome Database 3.0: a cross-species genome and transcriptome browser for yeast biologists. PMID:17212814
Puf3p, a Pumilio family RNA binding protein, localizes to mitochondria and regulates mitochondrial biogenesis and motility in budding yeast. PMID:17210948
Cex1p is a novel cytoplasmic component of the Saccharomyces cerevisiae nuclear tRNA export machinery. PMID:17203074
Rmd9p controls the processing/stability of mitochondrial mRNAs and its overexpression compensates for a partial deficiency of oxa1p in Saccharomyces cerevisiae. PMID:17194787
Translation initiation in Saccharomyces cerevisiae mitochondria: functional interactions among mitochondrial ribosomal protein Rsm28p, initiation factor 2, methionyl-tRNA-formyltransferase and novel protein Rmd9p. PMID:17194786
The carnegie protein trap library: a versatile tool for Drosophila developmental studies. PMID:17194782
Two mammalian Sec16 homologues have nonredundant functions in endoplasmic reticulum (ER) export and transitional ER organization. PMID:17192411
A Bayesian network driven approach to model the transcriptional response to nitric oxide in Saccharomyces cerevisiae. PMID:17183726
Contribution of Trf4/5 and the nuclear exosome to genome stability through regulation of histone mRNA levels in Saccharomyces cerevisiae. PMID:17179095
Exploring strategies for protein trapping in Drosophila. PMID:17179094
The alternative pathway of glutathione degradation is mediated by a novel protein complex involving three new genes in Saccharomyces cerevisiae. PMID:17179087
Bringing metabolic networks to life: integration of kinetic, metabolic, and proteomic data. PMID:17173670
Metabolite transport across the peroxisomal membrane. PMID:17173541
Treasure hunt in an amoeba: non-coding RNAs in Dictyostelium discoideum. PMID:17171561
Classical nuclear localization signals: definition, function, and interaction with importin alpha. PMID:17170104
Modeling complex genetic interactions in a simple eukaryotic genome: actin displays a rich spectrum of complex haploinsufficiencies. PMID:17167106
The Saccharomyces cerevisiae YFR041C/ERJ5 gene encoding a type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum. PMID:17157937
Mvb12 is a novel member of ESCRT-I involved in cargo selection by the multivesicular body pathway. PMID:17151358
The sensitivity of yeast mutants to oleic acid implicates the peroxisome and other processes in membrane function. PMID:17151231
Characterization of Saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesis. PMID:17145778
Efficient cargo sorting by ESCRT-I and the subsequent release of ESCRT-I from multivesicular bodies requires the subunit Mvb12. PMID:17135292
Organelle DB: an updated resource of eukaryotic protein localization and function. PMID:17130152
Protein microarray technology. PMID:17126887
Nuclear export modulates the cytoplasmic Sir2 homologue Hst2. PMID:17110954
eSLDB: eukaryotic subcellular localization database. PMID:17108361
A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. PMID:17101987
Analysis of the Saccharomyces cerevisiae proteome with PeptideAtlas. PMID:17101051
Specific SNARE complex binding mode of the Sec1/Munc-18 protein, Sec1p. PMID:17090679
Roles of phosphatidate phosphatase enzymes in lipid metabolism. PMID:17079146
Characteristics affecting expression and solubilization of yeast membrane proteins. PMID:17078969
Cytoplasmic decay of intergenic transcripts in Saccharomyces cerevisiae. PMID:17074811
An inventory of yeast proteins associated with nucleolar and ribosomal components. PMID:17067374
The spindle assembly checkpoint regulates the phosphorylation state of a subset of DNA checkpoint proteins in Saccharomyces cerevisiae. PMID:17060453
Assessing systems properties of yeast mitochondria through an interaction map of the organelle. PMID:17054397
Towards the identification of essential genes using targeted genome sequencing and comparative analysis. PMID:17052348
Proteomics of the peroxisome. PMID:17050007
Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer. PMID:17043313
The unfolded protein response transducer Ire1p contains a nuclear localization sequence recognized by multiple beta importins. PMID:17035634
Gis4, a new component of the ion homeostasis system in the yeast Saccharomyces cerevisiae. PMID:17030993
An entropic characterization of protein interaction networks and cellular robustness. PMID:17015299
Modelling the checkpoint response to telomere uncapping in budding yeast. PMID:17015293
Characterization and prediction of protein-protein interactions within and between complexes. PMID:17003128
Identification and comparative analysis of sixteen fungal peptidyl-prolyl cis/trans isomerase repertoires. PMID:16995943
Stratus not altocumulus: a new view of the yeast protein interaction network. PMID:16984220
Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p. PMID:16980630
Deletion of RNQ1 gene reveals novel functional relationship between divergently transcribed Bik1p/CLIP-170 and Sfi1p in spindle pole body separation. PMID:16972090
Spatial organization of transcription by RNA polymerase III. PMID:16971453
Predicting the subcellular localization of human proteins using machine learning and exploratory data analysis. PMID:16970551
Condensin function in mitotic nucleolar segregation is regulated by rDNA transcription. PMID:16969110
PLPD: reliable protein localization prediction from imbalanced and overlapped datasets. PMID:16966337
A fungal family of transcriptional regulators: the zinc cluster proteins. PMID:16959962
Organellar proteomics: turning inventories into insights. PMID:16953200
A survey of essential gene function in the yeast cell division cycle. PMID:16943325
The subcellular localization of the mammalian proteome comes a fraction closer. PMID:16938898
Conservation of expression and sequence of metabolic genes is reflected by activity across metabolic states. PMID:16933982
Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation. PMID:16923829
Quantification of protein half-lives in the budding yeast proteome. PMID:16916930
Actin bodies in yeast quiescent cells: an immediately available actin reserve? PMID:16914523
TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients. PMID:16888624
Ltv1 is required for efficient nuclear export of the ribosomal small subunit in Saccharomyces cerevisiae. PMID:16888326
Random insertion of a TetR-inducing peptide tag into Escherichia coli proteins allows analysis of protein levels by induction of reporter gene expression. PMID:16885321
Loc1p is required for efficient assembly and nuclear export of the 60S ribosomal subunit. PMID:16871394
Finding function: evaluation methods for functional genomic data. PMID:16869964
The WD40-repeat protein Pwp1p associates in vivo with 25S ribosomal chromatin in a histone H4 tail-dependent manner. PMID:16855292
Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. PMID:16850348
A global topology map of the Saccharomyces cerevisiae membrane proteome. PMID:16847258
Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae. PMID:16847257
Localizome: a server for identifying transmembrane topologies and TM helices of eukaryotic proteins utilizing domain information. PMID:16845118
A network of protein interactions determines polyglutamine toxicity. PMID:16832049
Four novel suppressors of gic1 gic2 and their roles in cytokinesis and polarized cell growth in Saccharomyces cerevisiae. PMID:16816427
The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae. PMID:16816426
Cell cycle-dependent regulation of Saccharomyces cerevisiae donor preference during mating-type switching by SBF (Swi4/Swi6) and Fkh1. PMID:16809780
Tpa1p is part of an mRNP complex that influences translation termination, mRNA deadenylation, and mRNA turnover in Saccharomyces cerevisiae. PMID:16809762
Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast. PMID:16790496
The novel F-box protein Mfb1p regulates mitochondrial connectivity and exhibits asymmetric localization in yeast. PMID:16790494
Distinct roles for TGN/endosome epsin-like adaptors Ent3p and Ent5p. PMID:16790491
Status of complete proteome analysis by mass spectrometry: SILAC labeled yeast as a model system. PMID:16784548
Sbp1p affects translational repression and decapping in Saccharomyces cerevisiae. PMID:16782896
The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. PMID:16769905
Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae. PMID:16762047
Identification of the major spliceosomal RNAs in Dictyostelium discoideum reveals developmentally regulated U2 variants and polyadenylated snRNAs. PMID:16757740
ELM1 is required for multidrug resistance in Saccharomyces cerevisiae. PMID:16751665
Sequences in the N-terminal cytoplasmic domain of Saccharomyces cerevisiae maltose permease are required for vacuolar degradation but not glucose-induced internalization. PMID:16741702
Expression and functional profiling reveal distinct gene classes involved in fatty acid metabolism. PMID:16738555
Systems-level analyses identify extensive coupling among gene expression machines. PMID:16738550
An intimate collaboration between peroxisomes and lipid bodies. PMID:16735577
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration. PMID:16725034
Saccharomyces cerevisiae cells have three Omega class glutathione S-transferases acting as 1-Cys thiol transferases. PMID:16709151
Role of Doa1 in the Saccharomyces cerevisiae DNA damage response. PMID:16705165
Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. PMID:16702403
PredSL: a tool for the N-terminal sequence-based prediction of protein subcellular localization. PMID:16689702
Laa1p, a conserved AP-1 accessory protein important for AP-1 localization in yeast. PMID:16687571
Dissection of Swa2p/auxilin domain requirements for cochaperoning Hsp70 clathrin-uncoating activity in vivo. PMID:16687570
Role of cell cycle-regulated expression in the localized incorporation of cell wall proteins in yeast. PMID:16672383
Nuclear recycling of the pre-60S ribosomal subunit-associated factor Arx1 depends on Rei1 in Saccharomyces cerevisiae. PMID:16648468
Structural stabilization of GTP-binding domains in circularly permuted GTPases: implications for RNA binding. PMID:16648363
Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. PMID:16642040
Prediction of yeast protein-protein interaction network: insights from the Gene Ontology and annotations. PMID:16641319
Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics. PMID:16635267
Mapping the Arabidopsis organelle proteome. PMID:16618929
Systematic analysis of Arabidopsis organelles and a protein localization database for facilitating fluorescent tagging of full-length Arabidopsis proteins. PMID:16617091
The La protein functions redundantly with tRNA modification enzymes to ensure tRNA structural stability. PMID:16581807
Plasma membrane localization of Ras requires class C Vps proteins and functional mitochondria in Saccharomyces cerevisiae. PMID:16581797
Kap120 functions as a nuclear import receptor for ribosome assembly factor Rpf1 in yeast. PMID:16581791
Esc4/Rtt107 and the control of recombination during replication. PMID:16569515
Functional partitioning of yeast co-expression networks after genome duplication. PMID:16555924
Conserved family of glycerol kinase loci in Drosophila melanogaster. PMID:16545593
Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. PMID:16537909
Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. PMID:16537494
Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. PMID:16510898
Systematic profiling of cellular phenotypes with spotted cell microarrays reveals mating-pheromone response genes. PMID:16507139
The use of biotin tagging in Saccharomyces cerevisiae improves the sensitivity of chromatin immunoprecipitation. PMID:16500888
An engineered nonsense URA3 allele provides a versatile system to detect the presence, absence and appearance of the [PSI+] prion in Saccharomyces cerevisiae. PMID:16491470
Requirement of fission yeast Cid14 in polyadenylation of rRNAs. PMID:16478992
Comparative gene expression analysis by differential clustering approach: application to the Candida albicans transcription program. PMID:16470937
Physiological importance and identification of novel targets for the N-terminal acetyltransferase NatB. PMID:16467477
The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme. PMID:16467296
Transcriptional activators in yeast. PMID:16464826
Domains within the GARP subunit Vps54 confer separate functions in complex assembly and early endosome recognition. PMID:16452629
Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1. PMID:16452505
Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing. PMID:16436512
The Saccharomyces cerevisiae spindle pole body (SPB) component Nbp1p is required for SPB membrane insertion and interacts with the integral membrane proteins Ndc1p and Mps2p. PMID:16436507
Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. PMID:16421251
Discovery of biological networks from diverse functional genomic data. PMID:16420673
Extension of chronological life span in yeast by decreased TOR pathway signaling. PMID:16418483
Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. PMID:16407407
Control of Bro1-domain protein Rim20 localization by external pH, ESCRT machinery, and the Saccharomyces cerevisiae Rim101 pathway. PMID:16407402
Casein kinase II phosphorylation of the yeast phospholipid synthesis transcription factor Opi1p. PMID:16407309
Actin-based motility during endocytosis in budding yeast. PMID:16394096
The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p. PMID:16390997
Prp43p is a DEAH-box spliceosome disassembly factor essential for ribosome biogenesis. PMID:16382144
The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis. PMID:16382143
MitoP2: the mitochondrial proteome database--now including mouse data. PMID:16381964
NOPdb: Nucleolar Proteome Database. PMID:16381850
Phosphorylation of the chromosomal passenger protein Bir1 is required for localization of Ndc10 to the spindle during anaphase and full spindle elongation. PMID:16381814
Yeast Trf5p is a nuclear poly(A) polymerase. PMID:16374505
Virus-like particles of the Ty3 retrotransposon assemble in association with P-body components. PMID:16373495
High-dimensional and large-scale phenotyping of yeast mutants. PMID:16365294
Yeast phosphatidylinositol 4-kinase, Pik1, has essential roles at the Golgi and in the nucleus. PMID:16365163
The 'interactome' of the Knr4/Smi1, a protein implicated in coordinating cell wall synthesis with bud emergence in Saccharomyces cerevisiae. PMID:16362369
Ulysses - an application for the projection of molecular interactions across species. PMID:16356269
A global view of CK2 function and regulation. PMID:16342414
The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. PMID:16341090
Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. PMID:16341089
Ascospore formation in the yeast Saccharomyces cerevisiae. PMID:16339736
Combining chemical genetics and proteomics to identify protein kinase substrates. PMID:16330754
Refining protein subcellular localization. PMID:16322766
Biochemical and genetic analysis of the yeast proteome with a movable ORF collection. PMID:16322557
Loss of dispensable genes is not adaptive in yeast. PMID:16314574
The essential WD40 protein Cia1 is involved in a late step of cytosolic and nuclear iron-sulfur protein assembly. PMID:16314508
Discover protein sequence signatures from protein-protein interaction data. PMID:16305745
A data integration methodology for systems biology: experimental verification. PMID:16301536
The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14. PMID:16287850
Saccharomyces cerevisiae Npc2p is a functionally conserved homologue of the human Niemann-Pick disease type C 2 protein, hNPC2. PMID:16278452
Gpi19, the Saccharomyces cerevisiae homologue of mammalian PIG-P, is a subunit of the initial enzyme for glycosylphosphatidylinositol anchor biosynthesis. PMID:16278447
INSIG: a broadly conserved transmembrane chaperone for sterol-sensing domain proteins. PMID:16270032
Trf4 and Trf5 proteins of Saccharomyces cerevisiae exhibit poly(A) RNA polymerase activity but no DNA polymerase activity. PMID:16260630
Identification and characterization of Elf1, a conserved transcription elongation factor in Saccharomyces cerevisiae. PMID:16260625
Gene CATCHR--gene cloning and tagging for Caenorhabditis elegans using yeast homologous recombination: a novel approach for the analysis of gene expression. PMID:16254074
The splicing ATPase prp43p is a component of multiple preribosomal particles. PMID:16227579
Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization. PMID:16209721
The YJR127C/ZMS1 gene product is involved in glycerol-based respiratory growth of the yeast Saccharomyces cerevisiae. PMID:16208474
A catalog of stability-associated sequence elements in 3' UTRs of yeast mRNAs. PMID:16207357
SIZ1/SIZ2 control of chromosome transmission fidelity is mediated by the sumoylation of topoisomerase II. PMID:16204216
Metabolic functions of duplicate genes in Saccharomyces cerevisiae. PMID:16204195
The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p. PMID:16186255
Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation. PMID:16172405
Characterization of the yeast ionome: a genome-wide analysis of nutrient mineral and trace element homeostasis in Saccharomyces cerevisiae. PMID:16168084
Pml39, a novel protein of the nuclear periphery required for nuclear retention of improper messenger ribonucleoparticles. PMID:16162818
Genome-wide transcription profiling of the early phase of biofilm formation by Candida albicans. PMID:16151249
Improved tagging strategy for protein identification in mammalian cells. PMID:16138932
Depletion of Saccharomyces cerevisiae tRNA(His) guanylyltransferase Thg1p leads to uncharged tRNAHis with additional m(5)C. PMID:16135808
Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. PMID:16121259
Large-scale identification of yeast integral membrane protein interactions. PMID:16093310
Multiple bromodomain genes are involved in restricting the spread of heterochromatic silencing at the Saccharomyces cerevisiae HMR-tRNA boundary. PMID:16079223
Condensin binding at distinct and specific chromosomal sites in the Saccharomyces cerevisiae genome. PMID:16055730
Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. PMID:16043514
Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae. PMID:16040803
Rpm2p, a component of yeast mitochondrial RNase P, acts as a transcriptional activator in the nucleus. PMID:16024791
Fzf1p regulates an inducible response to nitrosative stress in Saccharomyces cerevisiae. PMID:16014606
The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria. PMID:16009724
Genome-wide synthetic lethal screens identify an interaction between the nuclear envelope protein, Apq12p, and the kinetochore in Saccharomyces cerevisiae. PMID:15998715
The cyclophilins. PMID:15998457
Vertebrate GLD2 poly(A) polymerases in the germline and the brain. PMID:15987818
The novel fission yeast protein Pal1p interacts with Hip1-related Sla2p/End4p and is involved in cellular morphogenesis. PMID:15975911
Role for Gcs1p in regulation of Arl1p at trans-Golgi compartments. PMID:15975906
Esf2p, a U3-associated factor required for small-subunit processome assembly and compaction. PMID:15964808
Dsl1p, Tip20p, and the novel Dsl3(Sec39) protein are required for the stability of the Q/t-SNARE complex at the endoplasmic reticulum in yeast. PMID:15958492
Constitutive signal transduction by mutant Ssy5p and Ptr3p components of the SPS amino acid sensor system in Saccharomyces cerevisiae. PMID:15947203
ABG1, a novel and essential Candida albicans gene encoding a vacuolar protein involved in cytokinesis and hyphal branching. PMID:15947201
Cell wall integrity signaling in Saccharomyces cerevisiae. PMID:15944456
Metabolic engineering in the -omics era: elucidating and modulating regulatory networks. PMID:15944454
AVID: an integrative framework for discovering functional relationships among proteins. PMID:15929793
Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae. PMID:15928207
Global analysis of yeast RNA processing identifies new targets of RNase III and uncovers a link between tRNA 5' end processing and tRNA splicing. PMID:15920104
Genome-wide screen for inner nuclear membrane protein targeting in Saccharomyces cerevisiae: roles for N-acetylation and an integral membrane protein. PMID:15911569
Cooperative function of the CHD5-like protein Mdm39p with a P-type ATPase Spf1p in the maintenance of ER homeostasis in Saccharomyces cerevisiae. PMID:15909163
Targeting quantum dots to surface proteins in living cells with biotin ligase. PMID:15897449
Characterization of TRZ1, a yeast homolog of the human candidate prostate cancer susceptibility gene ELAC2 encoding tRNase Z. PMID:15892892
Sec17p and HOPS, in distinct SNARE complexes, mediate SNARE complex disruption or assembly for fusion. PMID:15889152
Nuclear import of TFIIB is mediated by Kap114p, a karyopherin with multiple cargo-binding domains. PMID:15888545
Filtering high-throughput protein-protein interaction data using a combination of genomic features. PMID:15833142
Snf1 kinase complexes with different beta subunits display stress-dependent preferences for the three Snf1-activating kinases. PMID:15824893
Forcing interactions as a genetic screen to identify proteins that exert a defined activity. PMID:15805496
Novel specificities emerge by stepwise duplication of functional modules. PMID:15805495
Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking. PMID:15802519
Rrp15p, a novel component of pre-ribosomal particles required for 60S ribosome subunit maturation. PMID:15769876
An early step in wobble uridine tRNA modification requires the Elongator complex. PMID:15769872
The aftiphilin/p200/gamma-synergin complex. PMID:15758025
A high-throughput screening of genes that encode proteins transported into the endoplasmic reticulum in mammalian cells. PMID:15731327
The eukaryotic P loop NTPase Nbp35: an essential component of the cytosolic and nuclear iron-sulfur protein assembly machinery. PMID:15728363
The Snf1 protein kinase and Sit4 protein phosphatase have opposing functions in regulating TATA-binding protein association with the Saccharomyces cerevisiae INO1 promoter. PMID:15716495
An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae. PMID:15715908
The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 genes encode a novel family of membrane-anchored lipases that are required for steryl ester hydrolysis. PMID:15713625
Processing bodies require RNA for assembly and contain nontranslating mRNAs. PMID:15703442
Rice Na+/H+-antiporter Nhx1 partially complements the alkali-metal-cation sensitivity of yeast strains lacking three sodium transporters. PMID:15702539
A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation. PMID:15695358
RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. PMID:15695330
Identification of growth phenotype-related genes in Aspergillus oryzae by heterologous macroarray and suppression subtractive hybridization. PMID:15678358
Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast. PMID:15657396
Lsb5p interacts with actin regulators Sla1p and Las17p, ubiquitin and Arf3p to couple actin dynamics to membrane trafficking processes. PMID:15651983
Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization. PMID:15643076
Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae. PMID:15643056
The deubiquitinating enzyme Ubp1 affects sorting of the ATP-binding cassette-transporter Ste6 in the endocytic pathway. PMID:15635103
Identification and assessment of the role of a nominal phospholipid binding region of ORP1S (oxysterol-binding-protein-related protein 1 short) in the regulation of vesicular transport. PMID:15617515
Organelle DB: a cross-species database of protein localization and function. PMID:15608270
Golgi inheritance in small buds of Saccharomyces cerevisiae is linked to endoplasmic reticulum inheritance. PMID:15596717
Gid8p (Dcr1p) and Dcr2p function in a common pathway to promote START completion in Saccharomyces cerevisiae. PMID:15590836
The small-subunit processome is a ribosome assembly intermediate. PMID:15590835
Morphogenetic pathway of spore wall assembly in Saccharomyces cerevisiae. PMID:15590821
Global protein function annotation through mining genome-scale data in yeast Saccharomyces cerevisiae. PMID:15585665
Uncovering novel cell cycle players through the inactivation of securin in budding yeast. PMID:15579722
Computational approaches for modeling regulatory cellular networks. PMID:15564042
2004 Irving Sigal Young Investigator Award. PMID:15557272
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PMID:15547975
Yeast chromatin assembly complex 1 protein excludes nonacetylatable forms of histone H4 from chromatin and the nucleus. PMID:15542829
Ypt31/32 GTPases and their novel F-box effector protein Rcy1 regulate protein recycling. PMID:15537705
On the mechanism of protein palmitoylation. PMID:15520806
Manganese toxicity and Saccharomyces cerevisiae Mam3p, a member of the ACDP (ancient conserved domain protein) family. PMID:15498024
A first version of the Caenorhabditis elegans Promoterome. PMID:15489340
Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. PMID:15485916
Short tetracysteine tags to beta-tubulin demonstrate the significance of small labels for live cell imaging. PMID:15469986
Predicting subcellular localization via protein motif co-occurrence. PMID:15466294
High-content screening microscopy identifies novel proteins with a putative role in secretory membrane traffic. PMID:15466293
Development of a method for screening short-lived proteins using green fluorescent protein. PMID:15461799
Biography of Erin K. O'Shea. PMID:15454611
Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism. PMID:15454531
The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association. PMID:15371542
Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression. PMID:15353587
The Swi/Snf chromatin remodeling complex is required for ribosomal DNA and telomeric silencing in Saccharomyces cerevisiae. PMID:15340082
A cotranscriptional model for 3'-end processing of the Saccharomyces cerevisiae pre-ribosomal RNA precursor. PMID:15337846
Protein networks, pleiotropy and the evolution of senescence. PMID:15306346
Modeling the function of bacterial virulence factors in Saccharomyces cerevisiae. PMID:15302815
RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits. PMID:15282305
Changes in the localization of the Saccharomyces cerevisiae anaphase-promoting complex upon microtubule depolymerization and spindle checkpoint activation. PMID:15280225
Novel conserved domains in proteins with predicted roles in eukaryotic cell-cycle regulation, decapping and RNA stability. PMID:15257761
The uses of genome-wide yeast mutant collections. PMID:15239820
The NEF4 complex regulates Rad4 levels and utilizes Snf2/Swi2-related ATPase activity for nucleotide excision repair. PMID:15226437
Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification. PMID:15226434
MITOPRED: a web server for the prediction of mitochondrial proteins. PMID:15215413
Saccharomyces cerevisiae multidrug transporter Qdr2p (Yil121wp): localization and function as a quinidine resistance determinant. PMID:15215105
Integrative analysis of the mitochondrial proteome in yeast. PMID:15208715
Npa1p is an essential trans-acting factor required for an early step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae. PMID:15208443
Tob38, a novel essential component in the biogenesis of beta-barrel proteins of mitochondria. PMID:15205677
Cdc14p/FEAR pathway controls segregation of nucleolus in S. cerevisiae by facilitating condensin targeting to rDNA chromatin in anaphase. PMID:15190202
Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. PMID:15189990
Automatic identification of subcellular phenotypes on human cell arrays. PMID:15173118
The J-protein family: modulating protein assembly, disassembly and translocation. PMID:15170475
Integrative analysis of cell cycle control in budding yeast. PMID:15169868
Yeast Mn2+ transporter, Smf1p, is regulated by ubiquitin-dependent vacuolar protein sorting. PMID:15166140
High-throughput fluorescent tagging of full-length Arabidopsis gene products in planta. PMID:15141064
Stochastic model of protein-protein interaction: why signaling proteins need to be colocalized. PMID:15096590
YBP1 and its homologue YBP2/YBH1 influence oxidative-stress tolerance by nonidentical mechanisms in Saccharomyces cerevisiae. PMID:15075262
ESF1 is required for 18S rRNA synthesis in Saccharomyces cerevisiae. PMID:15056729
A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin. PMID:15045029
Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast. PMID:15024427
A new enrichment approach identifies genes that alter cell cycle progression in Saccharomyces cerevisiae. PMID:15022016
The plant hormone indoleacetic acid induces invasive growth in Saccharomyces cerevisiae. PMID:15010530
Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution. PMID:14970192
Localizing the proteome. PMID:14659010
PRELI (protein of relevant evolutionary and lymphoid interest) is located within an evolutionarily conserved gene cluster on chromosome 5q34-q35 and encodes a novel mitochondrial protein. PMID:14640972

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eSLDB - eukaryotic Subcellular Localization database

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Mammalian Protein Localization Database

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Comprehensive Yeast Genome Database

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eSLDB - eukaryotic Subcellular Localization database

The Yeast Metabolome DataBase

ChimerDB

Mammalian Protein Localization Database

Yeast Resource Center Public Data Repository

Yeast Resource Center Public Image Repository

Yeast gene order browser

Yeast snoRNA Database

Yeast Phenotypes

LocDB

Comprehensive Yeast Genome Database

SCMD - Saccharomyces cerevisiae Morphological Database

yMGV - Yeast microarray global viewer

YDPM - Yeast Deletion Project

Yeast-Deletion-Library-Tools

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Online GEne Essentiality database

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Global analysis of protein localization in budding yeast
PMID: 14562095
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version: extracted_at: 2022-11-04T11:32:42.490315

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