How to Illuminate the Dark Proteome Using the Multi-omic OpenProt Resource. OpenProt is the first database that enforces a polycistronic model of eukaryotic genome annotations. Thus, OpenProt annotates known proteins (called RefProts) but also novel isoforms and novel proteins (called altProts). It also provides supporting evidence for each protein, such as mass-spectrometry and ribosome profiling detection, protein homology and predictions of funtional domains.
proteogenomics functional, regulatory and non-coding rna proteomics gene transcripts proteomics experiment