MiST 3.0: Microbial Signal Transduction database
Names
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MiST 3.0: Microbial Signal Transduction database
metasource: Fairsharing.org
version: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
MiST
metasource: Fairsharing.org
version: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
MIST
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
mist
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
Names
More detailed information about this field from each metasource.
MiST 3.0: Microbial Signal Transduction database
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
MiST
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
MIST
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
mist
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:30:31.924279
Names
More detailed information about this field from each metasource.
MiST 3.0: Microbial Signal Transduction database
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
MiST
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
MIST
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
mist
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:30:31.924279
Bacteria and archaea employ dedicated signal transduction systems that modulate gene expression, second-messenger turnover, quorum sensing, biofilm formation, motility, host-pathogen and beneficial interactions. The updated Microbial Signal Transduction (MiST) database provides a comprehensive classification of microbial signal transduction systems. This update is a result of a substantial scaling to accommodate constantly growing microbial genomic data. More than 125,000 genomes, 516 million genes and almost 100 million unique protein sequences are currently stored in the database. For each bacterial and archaeal genome, MiST 3.0 provides a complete signal transduction profile, thus facilitating theoretical and experimental studies on signal transduction and gene regulation. New software infrastructure and distributed pipeline implemented in MiST 3.0 enable regular genome updates based on the NCBI RefSeq database. A novel MiST feature is the integration of unique profile HMMs to link complex chemosensory systems with corresponding chemoreceptors in bacterial and archaeal genomes.
Description
More detailed information about this field from each metasource.
Bacteria and archaea employ dedicated signal transduction systems that modulate gene expression, second-messenger turnover, quorum sensing, biofilm formation, motility, host-pathogen and beneficial interactions. The updated Microbial Signal Transduction (MiST) database provides a comprehensive classification of microbial signal transduction systems. This update is a result of a substantial scaling to accommodate constantly growing microbial genomic data. More than 125,000 genomes, 516 million genes and almost 100 million unique protein sequences are currently stored in the database. For each bacterial and archaeal genome, MiST 3.0 provides a complete signal transduction profile, thus facilitating theoretical and experimental studies on signal transduction and gene regulation. New software infrastructure and distributed pipeline implemented in MiST 3.0 enable regular genome updates based on the NCBI RefSeq database. A novel MiST feature is the integration of unique profile HMMs to link complex chemosensory systems with corresponding chemoreceptors in bacterial and archaeal genomes.
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
Model organism and human databases are rich with information about genetic and physical interactions. These data can be used to interpret and guide the analysis of results from new studies and develop new hypotheses. Here, we report the development of the Molecular Interaction Search Tool (MIST; http://fgrtools.hms.harvard.edu/MIST/). The MIST database integrates biological interaction data from yeast, nematode, fly, zebrafish, frog, rat and mouse model systems, as well as human. For individual or short gene lists, the MIST user interface can be used to identify interacting partners based on protein–protein and genetic interaction (GI) data from the species of interest as well as inferred interactions, known as interologs, and to view a corresponding network. The data, interologs and search tools at MIST are also useful for analyzing ‘omics datasets. In addition to describing the integrated database, we also demonstrate how MIST can be used to identify an appropriate cut-off value that balances false positive and negative discovery, and present use-cases for additional types of analysis. Altogether, the MIST database and search tools support visualization and navigation of existing protein and GI data, as well as comparison of new and existing data.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Identifies and catalogs the repertoire of signal transduction proteins in microbial genomes. These are identified by searching protein sequences for specific domain profiles that implicate a protein in signal transduction. It contains a host of new features and improvements including the following: draft genomes; extracytoplasmic function (ECF) sigma factor protein identification; enhanced classification of signaling proteins; among others.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:30:31.924279
Webpage:
https://mistdb.com/Webpage
More detailed information about this field from each metasource.
https://mistdb.com/
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://fgrtools.hms.harvard.edu/ProteinSearch/
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
http://mistdb.com/
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:30:31.924279
Publications:
Publications
More detailed information about this field from each metasource.
The MiST2 database: a comprehensive genomics resource on microbial signal transduction
PMID: 19900966
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
http://dx.doi.org/10.1093/nar/gkz988
metasource: Fairsharing.org
version: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gkx1116
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
The MiST2 database: a comprehensive genomics resource on microbial signal transduction
PMID: 19900966
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
http://dx.doi.org/10.1093/nar/gkz988
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gkx1116
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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The MiST2 database: a comprehensive genomics resource on microbial signal transduction
PubMed citations: 159.
159 articles citing: The MiST2 database: a comprehensive genomics resource on microbial signal transduction
Comparative Genomics of Thaumarchaeota From Deep-Sea Sponges Reveal Their Niche Adaptation. PMID:35859738
The evolutionary path of chemosensory and flagellar macromolecular machines in Campylobacterota. PMID:35834583
The W-Acidic Motif of Histidine Kinase WalK Is Required for Signaling and Transcriptional Regulation in Streptococcus mutans. PMID:35558126
Evolutionary Principles of Bacterial Signaling Capacity and Complexity. PMID:35536007
The Vibrio cholerae master regulator for the activation of biofilm biogenesis genes, VpsR, senses both cyclic di-GMP and phosphate. PMID:35438787
The Hypoxia-Associated Localization of Chemotaxis Protein CheZ in Azorhizorbium caulinodans. PMID:34737727
Membrane Sensor Histidine Kinases: Insights from Structural, Ligand and Inhibitor Studies of Full-Length Proteins and Signalling Domains for Antibiotic Discovery. PMID:34443697
Maximization of information transmission influences selection of native phosphorelay architectures. PMID:34178454
HP1021 is a redox switch protein identified in Helicobacter pylori. PMID:34139017
Research progress on two-component signal transduction systems in Porphyromonas gingivalis. PMID:33723942
A Novel OmpR-Type Response Regulator Controls Multiple Stages of the Rhizobium etli - Phaseolus vulgaris N2-Fixing Symbiosis. PMID:33384681
Protein Residues and a Novel Motif Involved in the Cellular Localization of CheZ in Azorhizobium caulinodans ORS571. PMID:33365019
Signal transduction schemes in Pseudomonas syringae. PMID:33294136
Interface switch mediates signal transmission in a two-component system. PMID:33199635
Blue-light perception by epiphytic Pseudomonas syringae drives chemoreceptor expression, enabling efficient plant infection. PMID:33029921
De novo design of an intercellular signaling toolbox for multi-channel cell-cell communication and biological computation. PMID:32839450
Chemoreceptors with C-terminal pentapeptides for CheR and CheB binding are abundant in bacteria that maintain host interactions. PMID:32774789
A quantitative method for proteome reallocation using minimal regulatory interventions. PMID:32661378
A synthesis of bacterial and archaeal phenotypic trait data. PMID:32503990
Repurposing a chemosensory macromolecular machine. PMID:32341341
The impact of two-component sensorial network in staphylococcal speciation. PMID:32199334
Comparative genomics analysis of c-di-GMP metabolism and regulation in Microcystis aeruginosa. PMID:32151246
Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases. PMID:32034139
MiST 3.0: an updated microbial signal transduction database with an emphasis on chemosensory systems. PMID:31754718
Chemoperception of Specific Amino Acids Controls Phytopathogenicity in Pseudomonas syringae pv. tomato. PMID:31575767
In situ imaging of the bacterial flagellar motor disassembly and assembly processes. PMID:31304634
Identification and Characterization of the Two-Component System HK8700-RR8701 of Kocuria rhizophila DC2201. PMID:31302850
Chemotaxis Towards Aromatic Compounds: Insights from Comamonas testosteroni. PMID:31159416
Regulation of the Erythrobacter litoralis DSM 8509 general stress response by visible light. PMID:31125464
Evolutionary couplings of amino acid residues reveal structure and function of bacterial signaling proteins. PMID:31102561
An intramembrane sensory circuit monitors sortase A-mediated processing of streptococcal adhesins. PMID:31064885
Defining the regulon of genes controlled by σE , a key regulator of the cell envelope stress response in Streptomyces coelicolor. PMID:30907454
A PilZ-Containing Chemotaxis Receptor Mediates Oxygen and Wheat Root Sensing in Azospirillum brasilense. PMID:30881352
Cross Talk between Chemosensory Pathways That Modulate Chemotaxis and Biofilm Formation. PMID:30808696
Vancomycin does not affect the enzymatic activities of purified VanSA. PMID:30677074
The Core- and Pan-Genomic Analyses of the Genus Comamonas: From Environmental Adaptation to Potential Virulence. PMID:30619175
Orphan Hybrid Histidine Protein Kinase SinK Acts as a Signal Integrator To Fine-Tune Multicellular Behavior in Myxococcus xanthus. PMID:30617244
Suppressor mutations reveal an NtrC-like response regulator, NmpR, for modulation of Type-IV Pili-dependent motility in Myxococcus xanthus. PMID:30346960
In silico characterization of a novel putative aerotaxis chemosensory system in the myxobacterium, Corallococcus coralloides. PMID:30340510
Flexibility and constraint: Evolutionary remodeling of the sporulation initiation pathway in Firmicutes. PMID:30212463
What bacteria want. PMID:30187651
An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria. PMID:30065086
Concerted Metabolic Shifts Give New Insights Into the Syntrophic Mechanism Between Propionate-Fermenting Pelotomaculum thermopropionicum and Hydrogenotrophic Methanocella conradii. PMID:30038609
Ligand-Mediated Biofilm Formation via Enhanced Physical Interaction between a Diguanylate Cyclase and Its Receptor. PMID:29991582
Post-translational regulation of a Porphyromonas gingivalis regulator. PMID:29988788
The Treponema denticola PAS Domain-Containing Histidine Kinase Hpk2 Is a Heme Binding Sensor of Oxygen Levels. PMID:29986942
Insights into the Evolution of Host Association through the Isolation and Characterization of a Novel Human Periodontal Pathobiont, Desulfobulbus oralis. PMID:29535201
In silico comparative analysis of GGDEF and EAL domain signaling proteins from the Azospirillum genomes. PMID:29523074
Sensory deprivation in Staphylococcus aureus. PMID:29410457
The activity of the C4-dicarboxylic acid chemoreceptor of Pseudomonas aeruginosa is controlled by chemoattractants and antagonists. PMID:29391435
Phyletic Distribution and Lineage-Specific Domain Architectures of Archaeal Two-Component Signal Transduction Systems. PMID:29263101
Comparative Genomics of Myxobacterial Chemosensory Systems. PMID:29158239
A cheZ-Like Gene in Azorhizobium caulinodans Is a Key Gene in the Control of Chemotaxis and Colonization of the Host Plant. PMID:29150498
Assigning chemoreceptors to chemosensory pathways in Pseudomonas aeruginosa. PMID:29133402
The Pseudomonas putida CsrA/RsmA homologues negatively affect c-di-GMP pools and biofilm formation through the GGDEF/EAL response regulator CfcR. PMID:28677348
Analysis of complete genome sequence and major surface antigens of Neorickettsia helminthoeca, causative agent of salmon poisoning disease. PMID:28585301
Computational Exploration of Putative LuxR Solos in Archaea and Their Functional Implications in Quorum Sensing. PMID:28515720
The Role of the N-Terminal Domains of Bacterial Initiator DnaA in the Assembly and Regulation of the Bacterial Replication Initiation Complex. PMID:28489024
In vivo structures of an intact type VI secretion system revealed by electron cryotomography. PMID:28487352
Recent advances and future prospects in bacterial and archaeal locomotion and signal transduction. PMID:28484047
Class III Histidine Kinases: a Recently Accessorized Kinase Domain in Putative Modulators of Type IV Pilus-Based Motility. PMID:28484044
Fungal volatile compounds induce production of the secondary metabolite Sodorifen in Serratia plymuthica PRI-2C. PMID:28408760
Structure and function of HWE/HisKA2-family sensor histidine kinases. PMID:28193573
Architecture of the Vibrio cholerae toxin-coregulated pilus machine revealed by electron cryotomography. PMID:28165453
A direct-sensing galactose chemoreceptor recently evolved in invasive strains of Campylobacter jejuni. PMID:27762269
Identification of Functions Affecting Predator-Prey Interactions between Myxococcus xanthus and Bacillus subtilis. PMID:27698086
Atypical modes of bacterial histidine kinase signaling. PMID:27618209
A Variable Active Site Residue Influences the Kinetics of Response Regulator Phosphorylation and Dephosphorylation. PMID:27589219
Chemotaxis cluster 1 proteins form cytoplasmic arrays in Vibrio cholerae and are stabilized by a double signaling domain receptor DosM. PMID:27573843
Molecular Mechanisms of Two-Component Signal Transduction. PMID:27519796
Genetic Dissection of the Regulatory Network Associated with High c-di-GMP Levels in Pseudomonas putida KT2440. PMID:27489550
Experimental Analysis of Functional Variation within Protein Families: Receiver Domain Autodephosphorylation Kinetics. PMID:27381915
Promoter Recognition by Extracytoplasmic Function σ Factors: Analyzing DNA and Protein Interaction Motifs. PMID:27137497
Cache Domains That are Homologous to, but Different from PAS Domains Comprise the Largest Superfamily of Extracellular Sensors in Prokaryotes. PMID:27049771
The YsrS Paralog DygS Has the Capacity To Activate Expression of the Yersinia enterocolitica Ysa Type III Secretion System. PMID:27044629
A Chemotaxis Receptor Modulates Nodulation during the Azorhizobium caulinodans-Sesbania rostrata Symbiosis. PMID:26994081
Sister Dehalobacter Genomes Reveal Specialization in Organohalide Respiration and Recent Strain Differentiation Likely Driven by Chlorinated Substrates. PMID:26903979
(Actino)Bacterial "intelligence": using comparative genomics to unravel the information processing capacities of microbes. PMID:26852121
Evolutionary Genomics Suggests That CheV Is an Additional Adaptor for Accommodating Specific Chemoreceptors within the Chemotaxis Signaling Complex. PMID:26844549
Chemotaxis signaling systems in model beneficial plant-bacteria associations. PMID:26797793
Microbial Surface Colonization and Biofilm Development in Marine Environments. PMID:26700108
General Stress Signaling in the Alphaproteobacteria. PMID:26442844
Genome-wide prediction of prokaryotic two-component system networks using a sequence-based meta-predictor. PMID:26384938
Pili-Induced Clustering of N. gonorrhoeae Bacteria. PMID:26355966
A survey of HK, HPt, and RR domains and their organization in two-component systems and phosphorelay proteins of organisms with fully sequenced genomes. PMID:26339559
Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding. PMID:26321039
Structural asymmetry in a conserved signaling system that regulates division, replication, and virulence of an intracellular pathogen. PMID:26124143
Databases for Microbiologists. PMID:26013493
Employing aromatic tuning to modulate output from two-component signaling circuits. PMID:26000034
Data-driven integration of genome-scale regulatory and metabolic network models. PMID:25999934
Environmental Sensing in Actinobacteria: a Comprehensive Survey on the Signaling Capacity of This Phylum. PMID:25986905
Signal transduction in histidine kinases: insights from new structures. PMID:25982528
Probing Mechanistic Similarities between Response Regulator Signaling Proteins and Haloacid Dehalogenase Phosphatases. PMID:25928369
The cognitive cell: bacterial behavior reconsidered. PMID:25926819
Characterization of the Xylella fastidiosa PD1671 gene encoding degenerate c-di-GMP GGDEF/EAL domains, and its role in the development of Pierce's disease. PMID:25811864
Two-tiered histidine kinase pathway involved in heat shock and salt sensing in the general stress response of Sphingomonas melonis Fr1. PMID:25666137
Regulation of transcription by eukaryotic-like serine-threonine kinases and phosphatases in Gram-positive bacterial pathogens. PMID:25603430
Structural conservation of chemotaxis machinery across Archaea and Bacteria. PMID:25581459
Complex two-component signaling regulates the general stress response in Alphaproteobacteria. PMID:25404331
Histidine kinases mediate differentiation, stress response, and pathogenicity in Magnaporthe oryzae. PMID:25103193
SecDF as part of the Sec-translocase facilitates efficient secretion of Bacillus cereus toxins and cell wall-associated proteins. PMID:25083861
Chemosensory regulation of a HEAT-repeat protein couples aggregation and sporulation in Myxococcus xanthus. PMID:24957622
A putative bifunctional histidine kinase/phosphatase of the HWE family exerts positive and negative control on the Sinorhizobium meliloti general stress response. PMID:24794560
Characterization of an archaeal two-component system that regulates methanogenesis in Methanosaeta harundinacea. PMID:24748383
NEMiD: a web-based curated microbial diversity database with geo-based plotting. PMID:24714636
Structure of bacterial cytoplasmic chemoreceptor arrays and implications for chemotactic signaling. PMID:24668172
Identification of a novel nutrient-sensing histidine kinase/response regulator network in Escherichia coli. PMID:24659770
Sinorhizobium meliloti chemoreceptor McpU mediates chemotaxis toward host plant exudates through direct proline sensing. PMID:24657863
Essential role for the response regulator PmrA in Coxiella burnetii type 4B secretion and colonization of mammalian host cells. PMID:24610709
New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography. PMID:24580139
Escherichia coli isolate for studying colonization of the mouse intestine and its application to two-component signaling knockouts. PMID:24563035
Deciphering the regulon of Streptomyces coelicolor AbrC3, a positive response regulator of antibiotic production. PMID:24509929
Three antagonistic cyclic di-GMP-catabolizing enzymes promote differential Dot/Icm effector delivery and intracellular survival at the early steps of Legionella pneumophila infection. PMID:24379287
A phenylalanine rotameric switch for signal-state control in bacterial chemoreceptors. PMID:24335957
Canonical and non-canonical EcfG sigma factors control the general stress response in Rhizobium etli. PMID:24311555
Conformational coupling between receptor and kinase binding sites through a conserved salt bridge in a signaling complex scaffold protein. PMID:24244143
Specificity residues determine binding affinity for two-component signal transduction systems. PMID:24194534
Automated design of bacterial genome sequences. PMID:24160255
Homology modeling of the CheW coupling protein of the chemotaxis signaling complex. PMID:23950985
GoSynthetic database tool to analyse natural and engineered molecular processes. PMID:23813641
Histidine phosphotransfer proteins in fungal two-component signal transduction pathways. PMID:23771905
A link between dimerization and autophosphorylation of the response regulator PhoB. PMID:23760278
The 3.2 Å resolution structure of a receptor: CheA:CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial chemosensory arrays. PMID:23668907
P2RP: a Web-based framework for the identification and analysis of regulatory proteins in prokaryotic genomes. PMID:23601859
Characterization of five ECF sigma factors in the genome of Pseudomonas syringae pv. syringae B728a. PMID:23516563
Genomic reconstruction of the transcriptional regulatory network in Bacillus subtilis. PMID:23504016
Nonconserved active site residues modulate CheY autophosphorylation kinetics and phosphodonor preference. PMID:23458124
Genetic and biochemical dissection of a HisKA domain identifies residues required exclusively for kinase and phosphatase activities. PMID:23226719
A connecter-like factor, CacA, links RssB/RpoS and the CpxR/CpxA two-component system in Salmonella. PMID:23031642
Identification of proteins likely to be involved in morphogenesis, cell division, and signal transduction in Planctomycetes by comparative genomics. PMID:23002222
Extracytoplasmic function σ factors of the widely distributed group ECF41 contain a fused regulatory domain. PMID:22950025
An orphan chemotaxis sensor regulates virulence and antibiotic tolerance in the human pathogen Pseudomonas aeruginosa. PMID:22870303
Evolution of two-component signal transduction systems. PMID:22746333
Predicting inter-species cross-talk in two-component signalling systems. PMID:22629451
Different evolutionary modifications as a guide to rewire two-component systems. PMID:22586357
The passive yet successful way of planktonic life: genomic and experimental analysis of the ecology of a free-living polynucleobacter population. PMID:22448227
Extra cytoplasmic function σ factor activation. PMID:22381678
Azospirillum genomes reveal transition of bacteria from aquatic to terrestrial environments. PMID:22216014
Structural basis of response regulator inhibition by a bacterial anti-activator protein. PMID:22215984
Sinorhizobium meliloti CheA complexed with CheS exhibits enhanced binding to CheY1, resulting in accelerated CheY1 dephosphorylation. PMID:22194454
Direct-coupling analysis of residue coevolution captures native contacts across many protein families. PMID:22106262
Activated chemoreceptor arrays remain intact and hexagonally packed. PMID:21992450
CrdS and CrdA comprise a two-component system that is cooperatively regulated by the Che3 chemosensory system in Myxococcus xanthus. PMID:21810965
The atypical two-component sensor kinase Lpl0330 from Legionella pneumophila controls the bifunctional diguanylate cyclase-phosphodiesterase Lpl0329 to modulate bis-(3'-5')-cyclic dimeric GMP synthesis. PMID:21757706
Coevolution of ABC transporters and two-component regulatory systems as resistance modules against antimicrobial peptides in Firmicutes Bacteria. PMID:21665979
Comparative genomics of the dormancy regulons in mycobacteria. PMID:21602344
Dissecting the specificity of protein-protein interaction in bacterial two-component signaling: orphans and crosstalks. PMID:21573011
c-di-GMP turn-over in Clostridium difficile is controlled by a plethora of diguanylate cyclases and phosphodiesterases. PMID:21483756
Signal processing in complex chemotaxis pathways. PMID:21283116
The genetic organisation of prokaryotic two-component system signalling pathways. PMID:21172000
P2CS: a database of prokaryotic two-component systems. PMID:21051349
Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane. PMID:21049008
Identification of YsrT and evidence that YsrRST constitute a unique phosphorelay system in Yersinia enterocolitica. PMID:20870771
Origins and diversification of a complex signal transduction system in prokaryotes. PMID:20587806
The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments. PMID:20463976
Bacterial energy taxis: a global strategy? PMID:20411245
Diversity of structure and function of response regulator output domains. PMID:20226724
Interaction fidelity in two-component signaling. PMID:20133181
Evolution and phyletic distribution of two-component signal transduction systems. PMID:20133179 - http://dx.doi.org/10.1093/nar/gkz988
- http://dx.doi.org/10.1093/nar/gkx1116
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genome
metasource: Fairsharing.org
version: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
protein domain
metasource: Fairsharing.org
version: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
receptor
metasource: Fairsharing.org
version: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
signaling
metasource: Fairsharing.org
version: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
molecular interactions, pathways and networks
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
transcription factors and regulatory sites
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
model organisms
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
gene and protein families
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
protein folds and structural domains
metasource: bio.tools
version: extracted_at: 2022-11-04T11:30:31.924279
Tags
More detailed information about this field from each metasource.
genome
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
protein domain
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
receptor
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
signaling
metasource: Fairsharing.orgversion: FAIRsharing.org: MiST; MiST 3.0: Microbial Signal Transduction database; DOI: https://doi.org/10.25504/FAIRsharing.etXuEk; Last edited: Dec. 19, 2019, 11:06 a.m.; Last accessed: Jan 03 2022 7:07 p.m.
molecular interactions, pathways and networks
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:30:31.924279
transcription factors and regulatory sites
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:30:31.924279
model organisms
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:30:31.924279
gene and protein families
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:30:31.924279
protein folds and structural domains
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:30:31.924279
genome protein domain receptor signaling molecular interactions, pathways and networks transcription factors and regulatory sites model organisms gene and protein families protein folds and structural domains
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