MiCroKiTS
Names
More detailed information about this field from each metasource.
MiCroKiTS
metasource: Fairsharing.org
version: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
MiCroKitS
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
Midbody, Centrosome, Kinetochore and Spindle
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
formerly: MiCroKit
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
MiCroKit
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:01.449908
microkit
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:01.449908
Names
More detailed information about this field from each metasource.
MiCroKiTS
metasource: Fairsharing.orgversion: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
MiCroKitS
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
Midbody, Centrosome, Kinetochore and Spindle
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
formerly: MiCroKit
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
MiCroKit
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:01.449908
microkit
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:01.449908
Other names: MiCroKitS, Midbody, Centrosome, Kinetochore and Spindle, formerly: MiCroKit, MiCroKit, microkit
Names
More detailed information about this field from each metasource.
MiCroKiTS
metasource: Fairsharing.orgversion: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
MiCroKitS
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
Midbody, Centrosome, Kinetochore and Spindle
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
formerly: MiCroKit
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
MiCroKit
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:01.449908
microkit
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:01.449908
This resource is a collection of all proteins identified to be localized on kinetochore, centrosome, midbody, telomere and spindle from two fungi (S. cerevisiae and S. pombe) and five animals, including C. elegans, D. melanogaster, X. laevis, M. musculus and H. sapiens based on the rationale of "Seeing is believing" (Bloom K et al., 2005). Through ortholog searches, the proteins potentially localized at these sub-cellular regions were detected in 144 eukaryotes. Then the integrated and searchable database MiCroKiTS - Midbody, Centrosome, Kinetochore, Telomere and Spindle has been established. Currently, the MiCroKiTS 4.0 database was updated on Sep. 6, 2014, containing 87,983 unique protein entries.
Description
More detailed information about this field from each metasource.
This resource is a collection of all proteins identified to be localized on kinetochore, centrosome, midbody, telomere and spindle from two fungi (S. cerevisiae and S. pombe) and five animals, including C. elegans, D. melanogaster, X. laevis, M. musculus and H. sapiens based on the rationale of "Seeing is believing" (Bloom K et al., 2005). Through ortholog searches, the proteins potentially localized at these sub-cellular regions were detected in 144 eukaryotes. Then the integrated and searchable database MiCroKiTS - Midbody, Centrosome, Kinetochore, Telomere and Spindle has been established. Currently, the MiCroKiTS 4.0 database was updated on Sep. 6, 2014, containing 87,983 unique protein entries.
metasource: Fairsharing.orgversion: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
We reported an updated database of MiCroKiTS 4.0 (http://microkit.biocuckoo.org) for proteins temporally and spatially localized in distinct subcellular positions including midbody, centrosome, kinetochore, telomere and mitotic spindle during cell division/mitosis. The database was updated from our previously developed database of MiCroKit 3.0 (1), which contained 1,489 proteins mostly forming super-complexes at midbody, centrosome and kinetochore from seven eukaryotes. Since the telomere and spindle apparatus are critical for cell division, the proteins localized at the two positions were also integrated. From the scientific literature, we curated 1,872 experimentally identified proteins which at least locate in one of the five positions from eight species. Then the ortholog detection was performed to identify potential MiCroKiTS proteins from 144 eukaryotic organisms, which contains 66, 45 and 33 species of animals, fungi and plants, respectively. In total, 87,983 unique proteins with corresponding localization information were integrated into the database (2). The primary references of experimentally identified localizations were provided and the fluorescence microscope figures for the localizations of human proteins were shown. The orthologous relations between predicted and experimental localizations were also present. Taken together, we anticipate the database can serve as a useful resource for further analyzing the molecular mechanisms during cell division.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
During cell cycle, numerous proteins temporally and spatially localized in distinct sub-cellular regions including centrosome (spindle pole in budding yeast), kinetochore/centromere, cleavage furrow/midbody (related or homolog structures in plants and budding yeast called as phragmoplast and bud neck, respectively), telomere and spindle spatially and temporally. These sub-cellular regions play important roles in various biological processes. In this work, we have collected all proteins identified to be localized on kinetochore, centrosome, midbody, telomere and spindle from two fungi (S. cerevisiae and S. pombe) and five animals, including C. elegans, D. melanogaster, X. laevis, M. musculus and H. sapiens based on the rationale of "Seeing is believing" (Bloom K et al., 2005). Through ortholog searches, the proteins potentially localized at these sub-cellular regions were detected in 144 eukaryotes. Then the integrated and searchable database MiCroKiTS - Midbody, Centrosome, Kinetochore, Telomere and Spindle has been established.
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
Database of proteins that localize in midbody, centrosome and/or kinetochore. The database contains experimentally verified microkit proteins from the scientific literature that have unambiguous supportive evidence for subcellular localization under fluorescent microscope. Moreover, the orthologous information was provided for these microkit proteins, and could be a useful resource for further experimental identification.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:01.449908
Webpage:
http://microkit.biocuckoo.org/Webpage
More detailed information about this field from each metasource.
http://microkit.biocuckoo.org/
metasource: Fairsharing.orgversion: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:01.449908
http://microkit.biocuckoo.org
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
http://microkit.biocuckoo.org/index.php
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
Licence:
Name: Public DomainLicence name
More detailed information about this field from each metasource.
Public Domain
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
Licence URL
More detailed information about this field from each metasource.
http://microkit.biocuckoo.org/download.php
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
Publications:
Publications
More detailed information about this field from each metasource.
MiCroKit 3.0: an integrated database of midbody, centrosome and kinetochore
PMID: 19783819
metasource: Fairsharing.org
version: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:01.449908
MiCroKiTS 4.0: a database of midbody, centrosome, kinetochore, telomere and spindle
PMID: 25392421
metasource: Fairsharing.org
version: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://dx.doi.org/10.1093/nar/gku1125
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
MiCroKit 3.0: an integrated database of midbody, centrosome and kinetochore
PMID: 19783819
metasource: Fairsharing.org
version: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:01.449908
MiCroKiTS 4.0: a database of midbody, centrosome, kinetochore, telomere and spindle
PMID: 25392421
metasource: Fairsharing.org
version: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://dx.doi.org/10.1093/nar/gku1125
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
-
MiCroKit 3.0: an integrated database of midbody, centrosome and kinetochore
PubMed citations: 18.
18 articles citing: MiCroKit 3.0: an integrated database of midbody, centrosome and kinetochore
The SH2 domain and kinase activity of JAK2 target JAK2 to centrosome and regulate cell growth and centrosome amplification. PMID:35089929
Mutant p53 drives the loss of heterozygosity by the upregulation of Nek2 in breast cancer cells. PMID:33267874
Phase separation drives decision making in cell division. PMID:32699013
Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation. PMID:31444107
Gastric Parietal Cell Physiology and Helicobacter pylori-Induced Disease. PMID:30831083
An integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes. PMID:25400627
MiCroKiTS 4.0: a database of midbody, centrosome, kinetochore, telomere and spindle. PMID:25392421
JAK2 tyrosine kinase phosphorylates and is negatively regulated by centrosomal protein Ninein. PMID:25332239
Chromatin protein HP1 interacts with the mitotic regulator borealin protein and specifies the centromere localization of the chromosomal passenger complex. PMID:24917673
Coiled-coil proteins facilitated the functional expansion of the centrosome. PMID:24901223
PIPKIγ targets to the centrosome and restrains centriole duplication. PMID:24434581
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer. PMID:24282781
CentrosomeDB: a new generation of the centrosomal proteins database for Human and Drosophila melanogaster. PMID:24270791
Structure and non-structure of centrosomal proteins. PMID:23671615
New insights into subcomplex assembly and modifications of centrosomal proteins. PMID:22800182
GPS-ARM: computational analysis of the APC/C recognition motif by predicting D-boxes and KEN-boxes. PMID:22479614
Identification of a predominant co-regulation among kinetochore genes, prospective regulatory elements, and association with genomic instability. PMID:22016797
A role for central spindle proteins in cilia structure and function. PMID:21246755 -
MiCroKiTS 4.0: a database of midbody, centrosome, kinetochore, telomere and spindle
PubMed citations: 13.
13 articles citing: MiCroKiTS 4.0: a database of midbody, centrosome, kinetochore, telomere and spindle
RNALocate v2.0: an updated resource for RNA subcellular localization with increased coverage and annotation. PMID:34551440
Secreted midbody remnants are a class of extracellular vesicles molecularly distinct from exosomes and microparticles. PMID:33767328
The Emerging Role of ncRNAs and RNA-Binding Proteins in Mitotic Apparatus Formation. PMID:32245090
Phosphatidylinositol-5-phosphate 4-kinase gamma accumulates at the spindle pole and prevents microtubule depolymerization. PMID:31452676
PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia. PMID:30573780
Proteomic Profiling of Microtubule Self-organization in M-phase. PMID:29970457
TelNet - a database for human and yeast genes involved in telomere maintenance. PMID:29776332
THANATOS: an integrative data resource of proteins and post-translational modifications in the regulation of autophagy. PMID:29157087
PP2A-B' holoenzyme substrate recognition, regulation and role in cytokinesis. PMID:28884018
CGDB: a database of circadian genes in eukaryotes. PMID:27789706
The Clathrin-dependent Spindle Proteome. PMID:27174698
KinetochoreDB: a comprehensive online resource for the kinetochore and its related proteins. PMID:26989151
Midbody: from cellular junk to regulator of cell polarity and cell fate. PMID:25950842 - http://dx.doi.org/10.1093/nar/gku1125
Tags:
Tags
More detailed information about this field from each metasource.
protein
metasource: Fairsharing.org
version: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
protein sequence databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
protein localization and targeting
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
bioinformatics
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
chromosome
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
genetics
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
molecular biology
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
literature and language
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:01.449908
proteins
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:01.449908
animals
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:01.449908
model organisms
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:01.449908
Tags
More detailed information about this field from each metasource.
protein
metasource: Fairsharing.orgversion: FAIRsharing.org: MiCroKiTS; MiCroKiTS; DOI: https://doi.org/10.25504/FAIRsharing.3cswbc; Last edited: April 26, 2021, 8:39 a.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: re3data.org
version: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
protein sequence databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
protein localization and targeting
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
bioinformatics
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
chromosome
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
genetics
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
molecular biology
metasource: re3data.orgversion: re3data.org: MiCroKitS; editing status 2021-12-16; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R32P6K last accessed: 2022-11-04
literature and language
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:01.449908
proteins
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:01.449908
animals
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:01.449908
model organisms
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:01.449908
protein protein sequence protein localization and targeting bioinformatics chromosome genetics molecular biology literature and language proteins animals model organisms
Need help integrating and/or managing biomedical data?