Human Transcriptional Regulation Interactions database
Names
More detailed information about this field from each metasource.
Human Transcriptional Regulation Interactions database
metasource: Fairsharing.org
version: None
HTRIdb
metasource: Fairsharing.org
version: None
Names
More detailed information about this field from each metasource.
Human Transcriptional Regulation Interactions database
metasource: Fairsharing.orgversion: None
HTRIdb
metasource: Fairsharing.orgversion: None
Names
More detailed information about this field from each metasource.
Human Transcriptional Regulation Interactions database
metasource: Fairsharing.orgversion: None
HTRIdb
metasource: Fairsharing.orgversion: None
This source may no longer be available. No known URL could be resolved successfully.
The Human Transcriptional Regulation Interactions database (HTRIdb) is a repository of experimentally verified interactions among human transcription factors (TFs) and their respective target genes. It has been constructed to be an open-access and user-friendly database from which data on regulatory interactions among human TFs and their respective target genes can be easily extracted and then used, among other purposes, for building a global or a biological process-specific network of human transcriptional regulation interactions.
Description
More detailed information about this field from each metasource.
The Human Transcriptional Regulation Interactions database (HTRIdb) is a repository of experimentally verified interactions among human transcription factors (TFs) and their respective target genes. It has been constructed to be an open-access and user-friendly database from which data on regulatory interactions among human TFs and their respective target genes can be easily extracted and then used, among other purposes, for building a global or a biological process-specific network of human transcriptional regulation interactions.
metasource: Fairsharing.orgversion: None
Webpage:
http://www.lbbc.ibb.unesp.br/htri/index.jspWebpage
More detailed information about this field from each metasource.
Publications:
Publications
More detailed information about this field from each metasource.
HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions
PMID: 22900683
metasource: Fairsharing.org
version: None
Publications
More detailed information about this field from each metasource.
HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions
PMID: 22900683
metasource: Fairsharing.org
version: None
-
HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions
PubMed citations: 128.
128 articles citing: HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions
Systems Drug Discovery for Diffuse Large B Cell Lymphoma Based on Pathogenic Molecular Mechanism via Big Data Mining and Deep Learning Method. PMID:35743172
Tissue-Specific Variations in Transcription Factors Elucidate Complex Immune System Regulation. PMID:35627314
Transcriptome analysis of clock disrupted cancer cells reveals differential alternative splicing of cancer hallmarks genes. PMID:35552415
Repurposing Multiple-Molecule Drugs for COVID-19-Associated Acute Respiratory Distress Syndrome and Non-Viral Acute Respiratory Distress Syndrome via a Systems Biology Approach and a DNN-DTI Model Based on Five Drug Design Specifications. PMID:35409008
A novel network based linear model for prioritization of synergistic drug combinations. PMID:35381038
PITX1 Is a Regulator of TERT Expression in Prostate Cancer with Prognostic Power. PMID:35267575
Investigating the Role of Obesity in Prostate Cancer and Identifying Biomarkers for Drug Discovery: Systems Biology and Deep Learning Approaches. PMID:35164166
MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer. PMID:34877484
The impact of whole genome duplications on the human gene regulatory networks. PMID:34871317
Gene biomarker prediction in glioma by integrating scRNA-seq data and gene regulatory network. PMID:34863158
Identification of Cross-Pathway Connections via Protein-Protein Interactions Linked to Altered States of Metabolic Enzymes in Cervical Cancer. PMID:34790674
Tumor relevant protein functional interactions identified using bipartite graph analyses. PMID:34728699
Investigating Pathogenetic Mechanisms of Alzheimer's Disease by Systems Biology Approaches for Drug Discovery. PMID:34681938
Experiment level curation of transcriptional regulatory interactions in neurodevelopment. PMID:34665801
CellCall: integrating paired ligand-receptor and transcription factor activities for cell-cell communication. PMID:34331449
Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang. PMID:34297769
Single-Cell Transcriptome Analysis in Melanoma Using Network Embedding. PMID:34290746
Construction of Condition-Specific Gene Regulatory Network Using Kernel Canonical Correlation Analysis. PMID:34093651
Multiple-Molecule Drug Design Based on Systems Biology Approaches and Deep Neural Network to Mitigate Human Skin Aging. PMID:34073305
Computational Biology and Machine Learning Approaches to Understand Mechanistic Microbiome-Host Interactions. PMID:34046017
VB10, a new blood biomarker for differential diagnosis and recovery monitoring of acute viral and bacterial infections. PMID:33906069
Shared Molecular Mechanisms between Alzheimer's Disease and Periodontitis Revealed by Transcriptomic Analysis. PMID:33869630
Systems Medicine Design for Triple-Negative Breast Cancer and Non-Triple-Negative Breast Cancer Based on Systems Identification and Carcinogenic Mechanisms. PMID:33802957
Integrative analysis of transcriptomic data for identification of T-cell activation-related mRNA signatures indicative of preterm birth. PMID:33504832
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma. PMID:33495604
Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications. PMID:33375269
Analysis of Pan-omics Data in Human Interactome Network (APODHIN). PMID:33363571
DRIM: A Web-Based System for Investigating Drug Response at the Molecular Level by Condition-Specific Multi-Omics Data Integration. PMID:33281870
Investigating Core Signaling Pathways of Hepatitis B Virus Pathogenesis for Biomarkers Identification and Drug Discovery via Systems Biology and Deep Learning Method. PMID:32878239
Comprehensive Network Analysis Reveals Alternative Splicing-Related lncRNAs in Hepatocellular Carcinoma. PMID:32760422
A three-tiered integrative analysis of transcriptional data reveals the shared pathways related to heart failure from different aetiologies. PMID:32638546
ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct regulation and functions of these autophagy induction proteins. PMID:32616830
Phen2Gene: rapid phenotype-driven gene prioritization for rare diseases. PMID:32500119
Sex differences in autophagy-mediated diseases: toward precision medicine. PMID:32264724
CHG: A Systematically Integrated Database of Cancer Hallmark Genes. PMID:32117445
A New Weighted Imputed Neighborhood-Regularized Tri-Factorization One-Class Collaborative Filtering Algorithm: Application to Target Gene Prediction of Transcription Factors. PMID:31995498
Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach. PMID:31888467
The exploration of disease-specific gene regulatory networks in esophageal carcinoma and stomach adenocarcinoma. PMID:31888440
NicheNet: modeling intercellular communication by linking ligands to target genes. PMID:31819264
The Cytoscape BioGateway App: explorative network building from the BioGateway triple store. PMID:31710663
Measurement of Conditional Relatedness Between Genes Using Fully Convolutional Neural Network. PMID:31695723
The TargetMine Data Warehouse: Enhancement and Updates. PMID:31649722
The epigenetic factor BORIS (CTCFL) controls the androgen receptor regulatory network in ovarian cancer. PMID:31406110
A genome-wide positioning systems network algorithm for in silico drug repurposing. PMID:31375661
Benchmark and integration of resources for the estimation of human transcription factor activities. PMID:31340985
PropaNet: Time-Varying Condition-Specific Transcriptional Network Construction by Network Propagation. PMID:31258543
Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification. PMID:31217907
Target Gene Prediction of Transcription Factor Using a New Neighborhood-regularized Tri-factorization One-class Collaborative Filtering Algorithm. PMID:31061989
Exploration of prognosis-related microRNA and transcription factor co-regulatory networks across cancer types. PMID:31046554
Using Machine Learning to Measure Relatedness Between Genes: A Multi-Features Model. PMID:30862804
MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma. PMID:30765601
Gene Expression Profiling of NFATc1-Knockdown in RAW 264.7 Cells: An Alternative Pathway for Macrophage Differentiation. PMID:30736420
Identification of Prognostic Biomarker Signatures and Candidate Drugs in Colorectal Cancer: Insights from Systems Biology Analysis. PMID:30658502
CMTCN: a web tool for investigating cancer-specific microRNA and transcription factor co-regulatory networks. PMID:30473937
Investigating Pathogenic and Hepatocarcinogenic Mechanisms from Normal Liver to HCC by Constructing Genetic and Epigenetic Networks via Big Genetic and Epigenetic Data Mining and Genome-Wide NGS Data Identification. PMID:30344796
Investigating genetic-and-epigenetic networks, and the cellular mechanisms occurring in Epstein-Barr virus-infected human B lymphocytes via big data mining and genome-wide two-sided NGS data identification. PMID:30133498
Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective. PMID:30020984
EviNet: a web platform for network enrichment analysis with flexible definition of gene sets. PMID:29893885
A data-driven, knowledge-based approach to biomarker discovery: application to circulating microRNA markers of colorectal cancer prognosis. PMID:29872543
NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells. PMID:29739946
Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. PMID:29617668
BRCA-Pathway: a structural integration and visualization system of TCGA breast cancer data on KEGG pathways. PMID:29504910
Multitarget Effects of Danqi Pill on Global Gene Expression Changes in Myocardial Ischemia. PMID:29487863
In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer's Disease, Major Depressive Disorder, and Type 2 Diabetes. PMID:29441491
Differential gene expression induced by anti-cancer agent plumbagin is mediated by androgen receptor in prostate cancer cells. PMID:29426892
A phenotype centric benchmark of variant prioritisation tools. PMID:29423277
Alterations of specific chromatin conformation affect ATRA-induced leukemia cell differentiation. PMID:29422670
Collection and Curation of Transcriptional Regulatory Interactions in Aspergillus nidulans and Neurospora crassa Reveal Structural and Evolutionary Features of the Regulatory Networks. PMID:29403467
Biomarkers identification for acute myocardial infarction detection via weighted gene co-expression network analysis. PMID:29381915
Systematic target function annotation of human transcription factors. PMID:29325558
Regulatory activity based risk model identifies survival of stage II and III colorectal carcinoma. PMID:29228695
Integrative microRNA and mRNA deep-sequencing expression profiling in endemic Burkitt lymphoma. PMID:29132323
De novo pathway-based biomarker identification. PMID:28934488
Transcriptome analysis of inflammation-related gene expression in endothelial cells activated by complement MASP-1. PMID:28874747
CytoMCS: A Multiple Maximum Common Subgraph Detection Tool for Cytoscape. PMID:28731857
HDNetDB: A Molecular Interaction Database for Network-Oriented Investigations into Huntington's Disease. PMID:28701700
Differential co-expression analysis reveals a novel prognostic gene module in ovarian cancer. PMID:28694494
Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models. PMID:28481952
NEArender: an R package for functional interpretation of 'omics' data via network enrichment analysis. PMID:28361684
Identifying miRNA sponge modules using biclustering and regulatory scores. PMID:28361682
Gene expression profiles reveal key pathways and genes associated with neuropathic pain in patients with spinal cord injury. PMID:28260076
Identification of miRNA-mRNA Modules in Colorectal Cancer Using Rough Hypercuboid Based Supervised Clustering. PMID:28220871
Subtype-specific CpG island shore methylation and mutation patterns in 30 breast cancer cell lines. PMID:28155687
Identification of critical paralog groups with indispensable roles in the regulation of signaling flow. PMID:27922122
Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method. PMID:27821810
Genetic-and-Epigenetic Interspecies Networks for Cross-Talk Mechanisms in Human Macrophages and Dendritic Cells during MTB Infection. PMID:27803888
ORTI: An Open-Access Repository of Transcriptional Interactions for Interrogating Mammalian Gene Expression Data. PMID:27723773
Transcription factor HIF1A: downstream targets, associated pathways, polymorphic hypoxia response element (HRE) sites, and initiative for standardization of reporting in scientific literature. PMID:27644243
Properties of Boolean dynamics by node classification using feedback loops in a network. PMID:27558408
Functional characterization of EI24-induced autophagy in the degradation of RING-domain E3 ligases. PMID:27541728
A Bayesian algorithm for detecting differentially expressed proteins and its application in breast cancer research. PMID:27444576
Influence maximization in time bounded network identifies transcription factors regulating perturbed pathways. PMID:27307609
Investigating core genetic-and-epigenetic cell cycle networks for stemness and carcinogenic mechanisms, and cancer drug design using big database mining and genome-wide next-generation sequencing data. PMID:27295129
Inferring active regulatory networks from gene expression data using a combination of prior knowledge and enrichment analysis. PMID:27295045
Unmasking Upstream Gene Expression Regulators with miRNA-corrected mRNA Data. PMID:27279737
Network Biomarkers of Bladder Cancer Based on a Genome-Wide Genetic and Epigenetic Network Derived from Next-Generation Sequencing Data. PMID:27034531
An integrative data analysis platform for gene set analysis and knowledge discovery in a data warehouse framework. PMID:26989145
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling. PMID:26898226
Constructing an integrated genetic and epigenetic cellular network for whole cellular mechanism using high-throughput next-generation sequencing data. PMID:26897165
Investigating the specific core genetic-and-epigenetic networks of cellular mechanisms involved in human aging in peripheral blood mononuclear cells. PMID:26895224
Data in support of FSH induction of IRS-2 in human granulosa cells: Mapping the transcription factor binding sites in human IRS-2 promoter. PMID:26858982
Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types. PMID:26792175
Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis. PMID:26672765
Integrated analysis of global proteome, phosphoproteome, and glycoproteome enables complementary interpretation of disease-related protein networks. PMID:26657352
From System-Wide Differential Gene Expression to Perturbed Regulatory Factors: A Combinatorial Approach. PMID:26562430
Iterative sub-network component analysis enables reconstruction of large scale genetic networks. PMID:26537518
Identification of Novel Epigenetic Markers of Prostate Cancer by NotI-Microarray Analysis. PMID:26491211
Computational Systems Biology of Psoriasis: Are We Ready for the Age of Omics and Systems Biomarkers? PMID:26480058
Automated Identification of Core Regulatory Genes in Human Gene Regulatory Networks. PMID:26393364
Phenolyzer: phenotype-based prioritization of candidate genes for human diseases. PMID:26192085
Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth. PMID:26081588
Convergence behaviour and Control in Non-Linear Biological Networks. PMID:26068060
TRRUST: a reference database of human transcriptional regulatory interactions. PMID:26066708
Global transcription network incorporating distal regulator binding reveals selective cooperation of cancer drivers and risk genes. PMID:26001967
Bioinformatics analyses of significant prognostic risk markers for thyroid papillary carcinoma. PMID:25908172
Autophagy Regulatory Network - a systems-level bioinformatics resource for studying the mechanism and regulation of autophagy. PMID:25635527
Finding gene regulatory network candidates using the gene expression knowledge base. PMID:25490885
JUNB is a key transcriptional modulator of macrophage activation. PMID:25472994
A bayesian framework that integrates heterogeneous data for inferring gene regulatory networks. PMID:25152886
Inferring the perturbed microRNA regulatory networks from gene expression data using a network propagation based method. PMID:25069957
DiME: a scalable disease module identification algorithm with application to glioma progression. PMID:24523864
B-cell lymphoma gene regulatory networks: biological consistency among inference methods. PMID:24379827
A systems' biology approach to study microRNA-mediated gene regulatory networks. PMID:24350286
UniHI 7: an enhanced database for retrieval and interactive analysis of human molecular interaction networks. PMID:24214987
Prediction of oncogenic interactions and cancer-related signaling networks based on network topology. PMID:24204854
NRF2-ome: an integrated web resource to discover protein interaction and regulatory networks of NRF2. PMID:23710289
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review. PMID:23384594
SignaLink 2 - a signaling pathway resource with multi-layered regulatory networks. PMID:23331499
Tags:
Tags
More detailed information about this field from each metasource.
biological regulation
metasource: Fairsharing.org
version: None
experimental measurement
metasource: Fairsharing.org
version: None
experimentally determined
metasource: Fairsharing.org
version: None
molecular interaction
metasource: Fairsharing.org
version: None
regulation of gene expression
metasource: Fairsharing.org
version: None
regulatory region
metasource: Fairsharing.org
version: None
target
metasource: Fairsharing.org
version: None
transcription factor
metasource: Fairsharing.org
version: None
Tags
More detailed information about this field from each metasource.
biological regulation
metasource: Fairsharing.orgversion: None
experimental measurement
metasource: Fairsharing.orgversion: None
experimentally determined
metasource: Fairsharing.orgversion: None
molecular interaction
metasource: Fairsharing.orgversion: None
regulation of gene expression
metasource: Fairsharing.orgversion: None
regulatory region
metasource: Fairsharing.orgversion: None
target
metasource: Fairsharing.orgversion: None
transcription factor
metasource: Fairsharing.orgversion: None
biological regulation experimental measurement experimentally determined molecular interaction regulation of gene expression regulatory region target transcription
Need help integrating and/or managing biomedical data?