FAIRsharing.6e05x2; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

Other names: GDP Database

The GDP Database provides a public resource of gene disruptions of Drosophila genes using a single transposable element.

Webpage:

http://flypush.imgen.bcm.tmc.edu/pscreen/

Publications:

Publications
More detailed information about this field from each metasource.

The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes
PMID: 15238527
metasource: Fairsharing.org
version: FAIRsharing.org: GDP Database; Gene Disruption Project Database ; DOI: https://doi.org/10.25504/FAIRsharing.6e05x2; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes
PMID: 21985007
metasource: Fairsharing.org
version: FAIRsharing.org: GDP Database; Gene Disruption Project Database ; DOI: https://doi.org/10.25504/FAIRsharing.6e05x2; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

The Drosophila gene disruption project: progress using transposons with distinctive site specificities
PMID: 21515576
metasource: Fairsharing.org
version: FAIRsharing.org: GDP Database; Gene Disruption Project Database ; DOI: https://doi.org/10.25504/FAIRsharing.6e05x2; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila
PMID: 25824290
metasource: Fairsharing.org
version: FAIRsharing.org: GDP Database; Gene Disruption Project Database ; DOI: https://doi.org/10.25504/FAIRsharing.6e05x2; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

A genetic toolkit for tagging intronic MiMIC containing genes
PMID: 26102525
metasource: Fairsharing.org
version: FAIRsharing.org: GDP Database; Gene Disruption Project Database ; DOI: https://doi.org/10.25504/FAIRsharing.6e05x2; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes PubMed citations: 467.

467 articles citing: The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes

Corazonin Neurons Contribute to Dimorphic Ethanol Sedation Sensitivity in Drosophila melanogaster. PMID:35814486
TE Density: a tool to investigate the biology of transposable elements. PMID:35413944
Sidekick dynamically rebalances contractile and protrusive forces to control tissue morphogenesis. PMID:35258563
Engineered Sleeping Beauty transposase redirects transposon integration away from genes. PMID:35188569
A nutrient-specific gut hormone arbitrates between courtship and feeding. PMID:35140404
Mocs1 (Molybdenum cofactor synthesis 1) may contribute to lifespan extension in Drosophila. PMID:35098048
Mitochondria Dysfunction in Frontotemporal Dementia/Amyotrophic Lateral Sclerosis: Lessons From Drosophila Models. PMID:34899176
Synergistic epistasis of the deleterious effects of transposable elements. PMID:34888644
Expression of human HIPKs in Drosophila demonstrates their shared and unique functions in a developmental model. PMID:34849772
The disease-associated proteins Drosophila Nab2 and Ataxin-2 interact with shared RNAs and coregulate neuronal morphology. PMID:34791182
Glutamate metabolism directs energetic trade-offs to shape host-pathogen susceptibility in Drosophila. PMID:34710355
An ELISA-based method for rapid genetic screens in Drosophila. PMID:34686600
Phosphatidylserine synthase plays an essential role in glia and affects development, as well as the maintenance of neuronal function. PMID:34401677
The Microtubule Minus-End Binding Protein Patronin Is Required for the Epithelial Remodeling in the Drosophila Abdomen. PMID:34368132
Osmolarity-regulated swelling initiates egg activation in Drosophila. PMID:34343463
Ancestry analysis indicates two different sets of essential genes in eukaryotic model species. PMID:34279742
Characterizing dopaminergic neuron vulnerability using genome-wide analysis. PMID:34038543
Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB1 Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in Drosophila melanogaster. PMID:33912677
Systematic functional analysis of rab GTPases reveals limits of neuronal robustness to environmental challenges in flies. PMID:33666175
Combined use of feature engineering and machine-learning to predict essential genes in Drosophila melanogaster. PMID:33575603
Histone lysine methyltransferase Pr-set7/SETD8 promotes neural stem cell reactivation. PMID:33565211
RNAi-based screens uncover a potential new role for the orphan neuropeptide receptor Moody in Drosophila female germline stem cell maintenance. PMID:33307547
A versatile toolkit for CRISPR-Cas13-based RNA manipulation in Drosophila. PMID:33203452
Stac protein regulates release of neuropeptides. PMID:33168737
Oxidative stress modulates rearrangement of endoplasmic reticulum-mitochondria contacts and calcium dysregulation in a Friedreich's ataxia model. PMID:33128998
The Influence of Chromosomal Environment on X-Linked Gene Expression in Drosophila melanogaster. PMID:33104185
Rosy Beginnings: Studying Peroxisomes in Drosophila. PMID:32984330
A Genetic Screen Links the Disease-Associated Nab2 RNA-Binding Protein to the Planar Cell Polarity Pathway in Drosophila melanogaster. PMID:32817074
Selective Disruption of Synaptic BMP Signaling by a Smad Mutation Adjacent to the Highly Conserved H2 Helix. PMID:32737119
Double-edged sword: The evolutionary consequences of the epigenetic silencing of transposable elements. PMID:32673310
Transposable elements in Drosophila. PMID:32636946
CRISPR/Cas9 mediated genetic resource for unknown kinase and phosphatase genes in Drosophila. PMID:32355295
Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner. PMID:32343229
Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control. PMID:32339168
The fruitless gene affects female receptivity and species isolation. PMID:32208837
Antagonistic regulation by insulin-like peptide and activin ensures the elaboration of appropriate dendritic field sizes of amacrine neurons. PMID:32175842
Large-Scale Transgenic Drosophila Resource Collections for Loss- and Gain-of-Function Studies. PMID:32071193
Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy. PMID:32059717
Carrier of Wingless (Cow) Regulation of Drosophila Neuromuscular Junction Development. PMID:32024666
Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators. PMID:31955847
Antioxidant Therapy in Parkinson's Disease: Insights from Drosophila melanogaster. PMID:31936094
The polarity protein Dlg5 regulates collective cell migration during Drosophila oogenesis. PMID:31856229
Protein trap: a new Swiss army knife for geneticists? PMID:31728729
Social Context Enhances Hormonal Modulation of Pheromone Detection in Drosophila. PMID:31679932
Drosophila melanogaster as a Model System for Human Glioblastomas. PMID:31520357
Pharmaco-Genetic Screen To Uncover Actin Regulators Targeted by Prostaglandins During Drosophila Oogenesis. PMID:31506320
Functional divergence of Plexin B structural motifs in distinct steps of Drosophila olfactory circuit assembly. PMID:31225795
The α/β-hydrolase domain-containing 4- and 5-related phospholipase Pummelig controls energy storage in Drosophila. PMID:31164391
Protein Kinase D Is Dispensable for Development and Survival of Drosophila melanogaster. PMID:31142547
Patronin-mediated minus end growth is required for dendritic microtubule polarity. PMID:31076454
eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS. PMID:31023341
JNK signaling coordinates with ecdysone signaling to promote pruning of Drosophila sensory neuron dendrites. PMID:30936183
The RNA Helicase BELLE Is Involved in Circadian Rhythmicity and in Transposons Regulation in Drosophila melanogaster. PMID:30842743
Peroxisome-associated Sgroppino links fat metabolism with survival after RNA virus infection in Drosophila. PMID:30765784
A Context-Dependent Role for the RNF146 Ubiquitin Ligase in Wingless/Wnt Signaling in Drosophila. PMID:30593492
The role of the trithorax group TnaA isoforms in Hox gene expression, and in Drosophila late development. PMID:30372466
Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster. PMID:30341464
The Evolution of Small-RNA-Mediated Silencing of an Invading Transposable Element. PMID:30252073
The acyl-CoA Synthetase, pudgy, Promotes Sleep and Is Required for the Homeostatic Response to Sleep Deprivation. PMID:30186232
Stepwise wiring of the Drosophila olfactory map requires specific Plexin B levels. PMID:30136927
Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction. PMID:29901439
Src Cooperates with Oncogenic Ras in Tumourigenesis via the JNK and PI3K Pathways in Drosophila epithelial Tissue. PMID:29861494
Conserved Noncoding Elements Influence the Transposable Element Landscape in Drosophila. PMID:29850787
Reduced Neuronal Transcription of Escargot, the Drosophila Gene Encoding a Snail-Type Transcription Factor, Promotes Longevity. PMID:29760717
Regulation of the X Chromosome in the Germline and Soma of Drosophila melanogaster Males. PMID:29734690
Biosynthesis and assembly of the Collagen IV-like protein Pericardin in Drosophila melanogaster. PMID:29685999
Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila. PMID:29669801
Tethering of CHROMATOR and dCTCF proteins results in decompaction of condensed bands in the Drosophila melanogaster polytene chromosomes but does not affect their transcription and replication timing. PMID:29608600
Quorum-sensing regulator RhlR but not its autoinducer RhlI enables Pseudomonas to evade opsonization. PMID:29523648
Genetic cartography of longevity in humans and mice: Current landscape and horizons. PMID:29410319
Notch Target Gene E(spl)mδ Is a Mediator of Methylmercury-Induced Myotoxicity in Drosophila. PMID:29379520
Cyclin B3 Deficiency Impairs Germline Stem Cell Maintenance and Its Overexpression Delays Cystoblast Differentiation in Drosophila Ovary. PMID:29351213
Genetic and Neurobiological Analyses of the Noradrenergic-like System in Vulnerability to Sugar Overconsumption Using a Drosophila Model. PMID:29247240
Aubergine and piRNAs promote germline stem cell self-renewal by repressing the proto-oncogene Cbl. PMID:29030484
Metabolomic Analysis Reveals That the Drosophila melanogaster Gene lysine Influences Diverse Aspects of Metabolism. PMID:28986444
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila. PMID:28978772
Retrograde semaphorin-plexin signalling drives homeostatic synaptic plasticity. PMID:28953869
Drosophila Neprilysin 1 Rescues Memory Deficits Caused by Amyloid-β Peptide. PMID:28931572
The Notch pathway regulates the Second Mitotic Wave cell cycle independently of bHLH proteins. PMID:28919436
Anatomy and behavioral function of serotonin receptors in Drosophila melanogaster larvae. PMID:28777821
Exploring Autophagy in Drosophila. PMID:28704946
Peroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse. PMID:28640802
Vibrio cholerae ensures function of host proteins required for virulence through consumption of luminal methionine sulfoxide. PMID:28586382
The Genetic Architecture of Ovariole Number in Drosophila melanogaster: Genes with Major, Quantitative, and Pleiotropic Effects. PMID:28550012
Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc. PMID:28512185
Identification of octopaminergic neurons that modulate sleep suppression by male sex drive. PMID:28510528
Two Components of Aversive Memory in Drosophila, Anesthesia-Sensitive and Anesthesia-Resistant Memory, Require Distinct Domains Within the Rgk1 Small GTPase. PMID:28416593
Proteomics Analysis Identifies Orthologs of Human Chitinase-Like Proteins as Inducers of Tube Morphogenesis Defects in Drosophila melanogaster. PMID:28404605
Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular Diseases. PMID:28377694
Signaling pathway for phagocyte priming upon encounter with apoptotic cells. PMID:28325838
X-linkage is not a general inhibitor of tissue-specific gene expression in Drosophila melanogaster. PMID:28295031
Measuring and Altering Mating Drive in Male Drosophila melanogaster. PMID:28287580
Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegypti. PMID:28266580
The genetic basis for variation in resistance to infection in the Drosophila melanogaster genetic reference panel. PMID:28257468
Axon Termination, Pruning, and Synaptogenesis in the Giant Fiber System of Drosophila melanogaster Is Promoted by Highwire. PMID:28100586
Multidrug transporters and organic anion transporting polypeptides protect insects against the toxic effects of cardenolides. PMID:28011348
Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila. PMID:27809764
Olfactory receptor pseudo-pseudogenes. PMID:27776356
Green tea polyphenols require the mitochondrial iron transporter, mitoferrin, for lifespan extension in Drosophila melanogaster. PMID:27696504
The Insulin-Like Proteins dILPs-2/5 Determine Diapause Inducibility in Drosophila. PMID:27689881
Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense. PMID:27631699
A Drosophila LexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research. PMID:27527793
Coordinated movement, neuromuscular synaptogenesis and trans-synaptic signaling defects in Drosophila galactosemia models. PMID:27466186
Natural Genetic Variation and Candidate Genes for Morphological Traits in Drosophila melanogaster. PMID:27459710
Patronin/Shot Cortical Foci Assemble the Noncentrosomal Microtubule Array that Specifies the Drosophila Anterior-Posterior Axis. PMID:27404359
lolal Is an Evolutionarily New Epigenetic Regulator of dpp Transcription during Dorsal-Ventral Axis Formation. PMID:27401231
Inability to activate Rac1-dependent forgetting contributes to behavioral inflexibility in mutants of multiple autism-risk genes. PMID:27335463
Flow-dependent myosin recruitment during Drosophila cellularization requires zygotic dunk activity. PMID:27226317
The Spliceosomal Protein SF3B5 is a Novel Component of Drosophila SAGA that Functions in Gene Expression Independent of Splicing. PMID:27185460
Epithelia-derived wingless regulates dendrite directional growth of drosophila ddaE neuron through the Fz-Fmi-Dsh-Rac1 pathway. PMID:27129721
The initiator caspase Dronc is subject of enhanced autophagy upon proteasome impairment in Drosophila. PMID:27104928
Age-associated de-repression of retrotransposons in the Drosophila fat body, its potential cause and consequence. PMID:27072046
Novel mutants of the aubergine gene. PMID:27064345
Apontic regulates somatic stem cell numbers in Drosophila testes. PMID:26993259
Drosophila O-GlcNAcase Deletion Globally Perturbs Chromatin O-GlcNAcylation. PMID:26957542
FlyBase portals to human disease research using Drosophila models. PMID:26935103
Glial and neuronal Semaphorin signaling instruct the development of a functional myotopic map for Drosophila walking. PMID:26926907
The Drosophila tricellular junction protein Gliotactin regulates its own mRNA levels through BMP-mediated induction of miR-184. PMID:26906422
C-terminal Src Kinase Gates Homeostatic Synaptic Plasticity and Regulates Fasciclin II Expression at the Drosophila Neuromuscular Junction. PMID:26901416
Drosophila Nnf1 paralogs are partially redundant for somatic and germ line kinetochore function. PMID:26892014
Genome ARTIST: a robust, high-accuracy aligner tool for mapping transposon insertions and self-insertions. PMID:26855675
The Amino Acid Transporter JhI-21 Coevolves with Glutamate Receptors, Impacts NMJ Physiology, and Influences Locomotor Activity in Drosophila Larvae. PMID:26805723
Epistatic partners of neurogenic genes modulate Drosophila olfactory behavior. PMID:26678546
Towards a compendium of essential genes - From model organisms to synthetic lethality in cancer cells. PMID:26627871
The wavy Mutation Maps to the Inositol 1,4,5-Trisphosphate 3-Kinase 2 (IP3K2) Gene of Drosophila and Interacts with IP3R to Affect Wing Development. PMID:26613949
Genetics on the Fly: A Primer on the Drosophila Model System. PMID:26564900
Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila. PMID:26503115
Toll pathway modulates TNF-induced JNK-dependent cell death in Drosophila. PMID:26202785
P Transposable Elements in Drosophila and other Eukaryotic Organisms. PMID:26104714
Tissue landscape alters adjacent cell fates during Drosophila egg development. PMID:26082073
Sex Differences in Drosophila melanogaster Heterochromatin Are Regulated by Non-Sex Specific Factors. PMID:26053165
Genome-Wide Association Analyses Point to Candidate Genes for Electric Shock Avoidance in Drosophila melanogaster. PMID:25992709
A single-cross, RNA interference-based genetic tool for examining the long-term maintenance of homeostatic plasticity. PMID:25859184
The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer. PMID:25840432
The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy. PMID:25836674
Ih channels control feedback regulation from amacrine cells to photoreceptors. PMID:25831426
Loss of Pol32 in Drosophila melanogaster causes chromosome instability and suppresses variegation. PMID:25826374
A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb E3 ligases. PMID:25747658
Drosophila casein kinase I alpha regulates homolog pairing and genome organization by modulating condensin II subunit Cap-H2 levels. PMID:25723539
Generating customized transgene landing sites and multi-transgene arrays in Drosophila using phiC31 integrase. PMID:25680812
FMRFamide signaling promotes stress-induced sleep in Drosophila. PMID:25668617
Suppression of insulin production and secretion by a decretin hormone. PMID:25651184
An RNA-seq screen of the Drosophila antenna identifies a transporter necessary for ammonia detection. PMID:25412082
Signaling by the engulfment receptor draper: a screen in Drosophila melanogaster implicates cytoskeletal regulators, Jun N-terminal Kinase, and Yorkie. PMID:25395664
Differential centrifugation-based biochemical fractionation of the Drosophila adult CNS. PMID:25393777
Cloning and expression analysis of Drosophila extracellular Cu Zn superoxide dismutase. PMID:25339624
Survival of the fittest tools. PMID:25316776
Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. PMID:25294943
The Gos28 SNARE protein mediates intra-Golgi transport of rhodopsin and is required for photoreceptor survival. PMID:25261468
Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors. PMID:25201876
MicroRNA-8 promotes robust motor axon targeting by coordinate regulation of cell adhesion molecules during synapse development. PMID:25135978
piRNA clusters and open chromatin structure. PMID:25126116
A developmental genetic analysis of the lysine demethylase KDM2 mutations in Drosophila melanogaster. PMID:25016215
Peroxisomes are required for lipid metabolism and muscle function in Drosophila melanogaster. PMID:24945818
Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson's disease mutant of Leucine-Rich Repeat Kinase 2 (LRRK2). PMID:24915984
Contrasting influences of Drosophila white/mini-white on ethanol sensitivity in two different behavioral assays. PMID:24890118
New gene evolution in the bonus-TIF1-γ/TRIM33 family impacted the architecture of the vertebrate dorsal-ventral patterning network. PMID:24881051
Target organ specific activity of drosophila MRP (ABCC1) moderates developmental toxicity of methylmercury. PMID:24863968
The Little Fly that Could: Wizardry and Artistry of Drosophila Genomics. PMID:24827974
Water sensor ppk28 modulates Drosophila lifespan and physiology through AKH signaling. PMID:24821805
Lipid flippase modulates olfactory receptor expression and odorant sensitivity in Drosophila. PMID:24821794
A PCR-based forward genetics screening, using expression domain-specific markers, identifies mutants in endosperm transfer cell development. PMID:24808899
CMT-associated mutations in glycyl- and tyrosyl-tRNA synthetases exhibit similar pattern of toxicity and share common genetic modifiers in Drosophila. PMID:24807208
Evaluation of traditional medicines for neurodegenerative diseases using Drosophila models. PMID:24790636
Eye development. PMID:24784530
A nutritional conditional lethal mutant due to pyridoxine 5'-phosphate oxidase deficiency in Drosophila melanogaster. PMID:24739647
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. PMID:24714809
The Drosophila Werner exonuclease participates in an exonuclease-independent response to replication stress. PMID:24709634
Resources for functional genomics studies in Drosophila melanogaster. PMID:24653003
Farnesol-detecting olfactory neurons in Drosophila. PMID:24623773
Apical constriction drives tissue-scale hydrodynamic flow to mediate cell elongation. PMID:24590071
Regulation of Drosophila eye development by the transcription factor Sine oculis. PMID:24586968
Serotonin receptors expressed in Drosophila mushroom bodies differentially modulate larval locomotion. PMID:24586928
Loss of Trabid, a new negative regulator of the drosophila immune-deficiency pathway at the level of TAK1, reduces life span. PMID:24586180
Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster. PMID:24583113
Transcriptional properties and splicing of the flamenco piRNA cluster. PMID:24562610
Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in Drosophila. PMID:24478335
Neprilysins: an evolutionarily conserved family of metalloproteases that play important roles in reproduction in Drosophila. PMID:24395329
Comparison of ultra-conserved elements in drosophilids and vertebrates. PMID:24349264
Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression. PMID:24334454
The amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality control. PMID:24271015
The Drosophila gypsy insulator supports transvection in the presence of the vestigial enhancer. PMID:24236213
Regulation of epithelial morphogenesis by the G protein-coupled receptor mist and its ligand fog. PMID:24222713
The elongin complex antagonizes the chromatin factor Corto for vein versus intervein cell identity in Drosophila wings. PMID:24204884
The Drosophila ubiquitin-specific protease Puffyeye regulates dMyc-mediated growth. PMID:24173801
'Escaping' the X chromosome leads to increased gene expression in the male germline of Drosophila melanogaster. PMID:24022496
Signaling pathways involved in 1-octen-3-ol-mediated neurotoxicity in Drosophila melanogaster: implication in Parkinson’s disease. PMID:23959949
Control of tissue morphology by Fasciclin III-mediated intercellular adhesion. PMID:23946443
Invadolysin, a conserved lipid-droplet-associated metalloproteinase, is required for mitochondrial function in Drosophila. PMID:23943867
Gene-by-temperature interactions and candidate plasticity genes for morphological traits in Drosophila melanogaster. PMID:23936253
Genetic modifier screens to identify components of a redox-regulated cell adhesion and migration pathway. PMID:23849867
Neuronal necrosis and spreading death in a Drosophila genetic model. PMID:23846225
Combining genome-wide methods to investigate the genetic complexity of courtship song variation in Drosophila melanogaster. PMID:23777628
Chromatin and epigenetic features of long-range gene regulation. PMID:23766291
GATA simple sequence repeats function as enhancer blocker boundaries. PMID:23673629
Genome-wide association study of sleep in Drosophila melanogaster. PMID:23617951
Socs36E attenuates STAT signaling to optimize motile cell specification in the Drosophila ovary. PMID:23583584
Indy mutations and Drosophila longevity. PMID:23580130
Drosophila signal peptidase complex member Spase12 is required for development and cell differentiation. PMID:23573290
Genetic architecture of olfactory behavior in Drosophila melanogaster: differences and similarities across development. PMID:23563598
The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit. PMID:23509070
The piggyBac transposon displays local and distant reintegration preferences and can cause mutations at noncanonical integration sites. PMID:23358416
Identification and characterization of proteins involved in nuclear organization using Drosophila GFP protein trap lines. PMID:23341925
Decoupling epigenetic and genetic effects through systematic analysis of gene position. PMID:23291096
Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia. PMID:23263491
Genomic response to selection for postponed senescence in Drosophila. PMID:23262286
A hormone receptor-based transactivator bridges different binary systems to precisely control spatial-temporal gene expression in Drosophila. PMID:23239992
Expression of yeast NDI1 rescues a Drosophila complex I assembly defect. PMID:23226344
The bromodomain-containing protein tBRD-1 is specifically expressed in spermatocytes and is essential for male fertility. PMID:23213453
Tissue-specific regulation of chromatin insulator function. PMID:23209434
The Control of semaphorin-1a-mediated reverse signaling by opposing pebble and RhoGAPp190 functions in drosophila. PMID:23177958
Captured segment exchange: a strategy for custom engineering large genomic regions in Drosophila melanogaster. PMID:23150604
An SMN-dependent U12 splicing event essential for motor circuit function. PMID:23063131
Identification of genes underlying hypoxia tolerance in Drosophila by a P-element screen. PMID:23050227
Drosophila as a model to study mitochondrial dysfunction in Parkinson's disease. PMID:23024178
Induced transcription results in local changes in chromatin structure, replication timing, and DNA polytenization in a site of intercalary heterochromatin. PMID:23015267
Muscle length and myonuclear position are independently regulated by distinct Dynein pathways. PMID:22951643
Eukaryotic initiation factor 4E-3 is essential for meiotic chromosome segregation, cytokinesis and male fertility in Drosophila. PMID:22833128
Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response. PMID:22829770
Genome-wide association for sensitivity to chronic oxidative stress in Drosophila melanogaster. PMID:22715409
Bypassing the Greatwall-Endosulfine pathway: plasticity of a pivotal cell-cycle regulatory module in Drosophila melanogaster and Caenorhabditis elegans. PMID:22649080
A study of Epstein-Barr virus BRLF1 activity in a Drosophila model system. PMID:22629134
Drosophila activated Cdc42 kinase has an anti-apoptotic function. PMID:22615583
A screen for genes expressed in the olfactory organs of Drosophila melanogaster identifies genes involved in olfactory behaviour. PMID:22530061
Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. PMID:22496853
Whacked and Rab35 polarize dynein-motor-complex-dependent seamless tube growth. PMID:22407366
Dopaminergic modulation of sucrose acceptance behavior in Drosophila. PMID:22405204
Drosophila Reporter Vectors Compatible with ΦC31 Integrase Transgenesis Techniques and Their Use to Generate New Notch Reporter Fly Lines. PMID:22384384
The Drosophila melanogaster host model. PMID:22368770
Exploiting Drosophila genetics to understand microRNA function and regulation. PMID:22365740
Extensive epistasis for olfactory behaviour, sleep and waking activity in Drosophila melanogaster. PMID:22353245
Drosophila melanogaster as a model to study drug addiction. PMID:22350798
The Drosophila melanogaster Genetic Reference Panel. PMID:22318601
P-element homing is facilitated by engrailed polycomb-group response elements in Drosophila melanogaster. PMID:22276200
Schnurri regulates hemocyte function to promote tissue recovery after DNA damage. PMID:22275438
Drosophila SOCS Proteins. PMID:22203896
Functional genome annotation of Drosophila seminal fluid proteins using transcriptional genetic networks. PMID:22189604
Protein composition of interband regions in polytene and cell line chromosomes of Drosophila melanogaster. PMID:22093916
SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless. PMID:22041890
EGFR signaling modulates synaptic connectivity via Gurken. PMID:22021126
Genetic manipulation of genes and cells in the nervous system of the fruit fly. PMID:22017985
Stathmin is required for stability of the Drosophila neuromuscular junction. PMID:22016536
MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes. PMID:21985007
Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. PMID:21949350
A genetic in vivo system to detect asymmetrically distributed RNA. PMID:21921935
Drosophila, genetic screens, and cardiac function. PMID:21921272
Drosophila P elements preferentially transpose to replication origins. PMID:21896744
Drosophila Ten-m and filamin affect motor neuron growth cone guidance. PMID:21857973
Rich regulates target specificity of photoreceptor cells and N-cadherin trafficking in the Drosophila visual system via Rab6. PMID:21835342
Access to DNA establishes a secondary target site bias for the yeast retrotransposon Ty5. PMID:21788500
A novel function for the PAR complex in subcellular morphogenesis of tracheal terminal cells in Drosophila melanogaster. PMID:21750259
Genetic basis of wing morphogenesis in Drosophila: sexual dimorphism and non-allometric effects of shape variation. PMID:21635778
Anterior-posterior axis specification in Drosophila oocytes: identification of novel bicoid and oskar mRNA localization factors. PMID:21625003
Unc-51/ATG1 controls axonal and dendritic development via kinesin-mediated vesicle transport in the Drosophila brain. PMID:21589871
Drosophila melanogaster as a model system for human brain cancers. PMID:21538561
Effective generation of transgenic reporter and gene trap lines of the medaka (Oryzias latipes) using the Ac/Ds transposon system. PMID:21533666
Transcription initiation from within P elements generates hypomorphic mutations in Drosophila melanogaster. PMID:21527778
The Drosophila gene disruption project: progress using transposons with distinctive site specificities. PMID:21515576
Opposing roles of PlexinA and PlexinB in axonal branch and varicosity formation. PMID:21489263
A link between impaired purine nucleotide synthesis and apoptosis in Drosophila melanogaster. PMID:21441212
The Putzig-NURF nucleosome remodeling complex is required for ecdysone receptor signaling and innate immunity in Drosophila melanogaster. PMID:21385730
The Batten disease gene CLN3 is required for the response to oxidative stress. PMID:21372148
Blanks, a nuclear siRNA/dsRNA-binding complex component, is required for Drosophila spermiogenesis. PMID:21300896
Neurotransmitter Transporter-Like: a male germline-specific SLC6 transporter required for Drosophila spermiogenesis. PMID:21298005
Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. PMID:21295279
Transcriptional networks for alcohol sensitivity in Drosophila melanogaster. PMID:21270389
Heterotrimeric kinesin-II is necessary and sufficient to promote different stepwise assembly of morphologically distinct bipartite cilia in Drosophila antenna. PMID:21233284
Identification of functional elements and regulatory circuits by Drosophila modENCODE. PMID:21177974
Molecular population genetics and selection in the glycolytic pathway. PMID:21177937
Genetic approaches to alcohol addiction: gene expression studies and recent candidates from Drosophila. PMID:21153676
ftz-f1 and Hr39 opposing roles on EcR expression during Drosophila mushroom body neuron remodeling. PMID:21131955
DNA transposon Hermes inserts into DNA in nucleosome-free regions in vivo. PMID:21131571
Drosophila glia use a conserved cotransporter mechanism to regulate extracellular volume. PMID:21125654
Control of germline torso expression by the BTB/POZ domain protein pipsqueak is required for embryonic terminal patterning in Drosophila. PMID:21098720
Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species. PMID:21075834
Analysis of thioester-containing proteins during the innate immune response of Drosophila melanogaster. PMID:21063077
Central regulation of locomotor behavior of Drosophila melanogaster depends on a CASK isoform containing CaMK-like and L27 domains. PMID:21059886
Porphyromonas gingivalis-host interactions in a Drosophila melanogaster model. PMID:21041486
A new resource for characterizing X-linked genes in Drosophila melanogaster: systematic coverage and subdivision of the X chromosome with nested, Y-linked duplications. PMID:20876560
Bacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseases. PMID:20818735
Reverse genetics in eukaryotes. PMID:20812916
Drosophila ataxin 2-binding protein 1 marks an intermediate step in the molecular differentiation of female germline cysts. PMID:20724451
Peristalsis in the junction region of the Drosophila larval midgut is modulated by DH31 expressing enteroendocrine cells. PMID:20698983
Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. PMID:20686706
An evolutionarily conserved arginine is essential for Tre1 G protein-coupled receptor function during germ cell migration in Drosophila melanogaster. PMID:20676220
The Drosophila homolog of the mammalian imprint regulator, CTCF, maintains the maternal genomic imprint in Drosophila melanogaster. PMID:20673338
NELF potentiates gene transcription in the Drosophila embryo. PMID:20634899
BrainTrap: a database of 3D protein expression patterns in the Drosophila brain. PMID:20624714
A conserved role for syndecan family members in the regulation of whole-body energy metabolism. PMID:20585652
Paucity and preferential suppression of transgenes in late replication domains of the D. melanogaster genome. PMID:20492674
Evidence for an essential deglycosylation-independent activity of PNGase in Drosophila melanogaster. PMID:20479940
The gang of four gene regulates growth and patterning of the developing Drosophila eye. PMID:20473027
Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. PMID:20439780
A perisynaptic ménage à trois between Dlg, DLin-7, and Metro controls proper organization of Drosophila synaptic junctions. PMID:20427642
Recruitment of Cdc20 to the kinetochore requires BubR1 but not Mad2 in Drosophila melanogaster. PMID:20421417
100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future. PMID:20383202
Essential loci in centromeric heterochromatin of Drosophila melanogaster. I: the right arm of chromosome 2. PMID:20382826
The function and regulation of the bHLH gene, cato, in Drosophila neurogenesis. PMID:20346138
Flightless flies: Drosophila models of neuromuscular disease. PMID:20329357
Endocytic internalization routes required for delta/notch signaling. PMID:20226669
Identifying cellular pathways modulated by Drosophila palmitoyl-protein thioesterase 1 function. PMID:20206262
Molecular evolution and functional characterization of Drosophila insulin-like peptides. PMID:20195512
New research resources at the Bloomington Drosophila Stock Center. PMID:20160480
The role of p38b MAPK in age-related modulation of intestinal stem cell proliferation and differentiation in Drosophila. PMID:20157545
Tenectin is a novel alphaPS2betaPS integrin ligand required for wing morphogenesis and male genital looping in Drosophila. PMID:20152825
Neurologic dysfunction and male infertility in Drosophila porin mutants: a new model for mitochondrial dysfunction and disease. PMID:20110367
Exploring prion protein biology in flies: genetics and beyond. PMID:20083902
Contrasting patterns of transposable element insertions in Drosophila heat-shock promoters. PMID:20041194
Rab3 dynamically controls protein composition at active zones. PMID:20005823
Rab3 GTPase lands Bruchpilot. PMID:20005815
Regulation of epithelial stem cell replacement and follicle formation in the Drosophila ovary. PMID:19948890
A modifier screen in the Drosophila eye reveals that aPKC interacts with Glued during central synapse formation. PMID:19948010
A neural circuit mechanism integrating motivational state with memory expression in Drosophila. PMID:19837040
Drosophila melanogaster as a model system for genetics of postnatal cardiac function. PMID:19802348
Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function. PMID:19758432
The evolutionarily conserved RNA binding protein SMOOTH is essential for maintaining normal muscle function. PMID:19755840
A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis. PMID:19737521
Removal of the bloom syndrome DNA helicase extends the utility of imprecise transposon excision for making null mutations in Drosophila. PMID:19687136
Alcohol sensitivity in Drosophila: translational potential of systems genetics. PMID:19652175
The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine. PMID:19647043
Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling. PMID:19640479
Maturation of active zone assembly by Drosophila Bruchpilot. PMID:19596851
Energy stores are not altered by long-term partial sleep deprivation in Drosophila melanogaster. PMID:19593430
Drosophila RISC component VIG and its homolog Vig2 impact heterochromatin formation. PMID:19584931
Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia. PMID:19581577
Positional cues in the Drosophila nerve cord: semaphorins pattern the dorso-ventral axis. PMID:19547742
Unlocking the secrets of the genome. PMID:19536255
Mutations in many genes affect aggressive behavior in Drosophila melanogaster. PMID:19519879
Intracellular Ca2+ signaling and store-operated Ca2+ entry are required in Drosophila neurons for flight. PMID:19515818
Biases in Drosophila melanogaster protein trap screens. PMID:19476619
Application of TILLING and EcoTILLING as Reverse Genetic Approaches to Elucidate the Function of Genes in Plants and Animals. PMID:19452039
Large-scale functional annotation and expanded implementations of the P{wHy} hybrid transposon in the Drosophila melanogaster genome. PMID:19398769
Select Drosophila glomeruli mediate innate olfactory attraction and aversion. PMID:19396157
The multi-AT-hook chromosomal protein of Drosophila melanogaster, D1, is dispensable for viability. PMID:19293138
Frequent unanticipated alleles of lethal giant larvae in Drosophila second chromosome stocks. PMID:19279324
A presynaptic homeostatic signaling system composed of the Eph receptor, ephexin, Cdc42, and CaV2.1 calcium channels. PMID:19249276
Systematic functional analysis of Bicaudal-D serine phosphorylation and intragenic suppression of a female sterile allele of BicD. PMID:19234596
Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep. PMID:19234472
Complex interplay of three transcription factors in controlling the tormogen differentiation program of Drosophila mechanoreceptors. PMID:19232522
Bicaudal C and trailer hitch have similar roles in gurken mRNA localization and cytoskeletal organization. PMID:19217894
Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons. PMID:19164766
Reduced fertility of Drosophila melanogaster hybrid male rescue (Hmr) mutant females is partially complemented by Hmr orthologs from sibling species. PMID:19153254
Transgenic tools for Drosophila muscle research. PMID:19152055
Unc-51 controls active zone density and protein composition by downregulating ERK signaling. PMID:19144852
ben Functions with scamp during synaptic transmission and long-term memory formation in Drosophila. PMID:19144841
A motor function for the DEAD-box RNA helicase, Gemin3, in Drosophila. PMID:19023405
The UCSC Genome Browser Database: update 2009. PMID:18996895
Requirement for a core 1 galactosyltransferase in the Drosophila nervous system. PMID:18985719
Construction and characterization of deletions with defined end points in Drosophila using P elements in trans. PMID:18984572
Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formation. PMID:18957704
An amino acid polymorphism in the couch potato gene forms the basis for climatic adaptation in Drosophila melanogaster. PMID:18852464
Overexpression screen in Drosophila identifies neuronal roles of GSK-3 beta/shaggy as a regulator of AP-1-dependent developmental plasticity. PMID:18832361
Testing the palindromic target site model for DNA transposon insertion using the Drosophila melanogaster P-element. PMID:18829720
The genetic architecture of complex behaviors: lessons from Drosophila. PMID:18758968
A genetic screen identifies new regulators of steroid-triggered programmed cell death in Drosophila. PMID:18757938
A misexpression screen to identify regulators of Drosophila larval hemocyte development. PMID:18757933
HP1 is distributed within distinct chromatin domains at Drosophila telomeres. PMID:18723888
The dominant cold-sensitive Out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic. PMID:18723887
Tissue-specific defects are caused by loss of the Drosophila MAN1 LEM domain protein. PMID:18723885
Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. PMID:18713854
E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage. PMID:18688282
Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway. PMID:18688280
Chromosomal rearrangement inferred from comparisons of 12 Drosophila genomes. PMID:18622036
Identification of JAK/STAT pathway regulators--insights from RNAi screens. PMID:18586112
A novel ecdysone receptor mediates steroid-regulated developmental events during the mid-third instar of Drosophila. PMID:18566664
Functional characterization of the dRYBP gene in Drosophila. PMID:18562658
Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure. PMID:18562639
G protein-coupled receptor kinase 2 is required for rhythmic olfactory responses in Drosophila. PMID:18499458
Coincidence of P-insertion sites and breakpoints of deletions induced by activating P elements in Drosophila. PMID:18493052
An RGS-containing sorting nexin controls Drosophila lifespan. PMID:18478054
Quantitative genetic analysis of sleep in Drosophila melanogaster. PMID:18430954
Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. PMID:18419806
straightjacket is required for the synaptic stabilization of cacophony, a voltage-gated calcium channel alpha1 subunit. PMID:18391075
Synaptic defects in a Drosophila model of congenital muscular dystrophy. PMID:18385336
New components of the Drosophila fusome suggest it plays novel roles in signaling and transport. PMID:18355804
Crag regulates epithelial architecture and polarized deposition of basement membrane proteins in Drosophila. PMID:18331716
Drosophila melanogaster as a model system to study mitochondrial biology. PMID:18314716
Mechanical stimulation by osmotic and hydrostatic pressure activates Drosophila oocytes in vitro in a calcium-dependent manner. PMID:18304524
piggyBac-based mosaic screen identifies a postmitotic function for cohesin in regulating developmental axon pruning. PMID:18267091
Conditional switches for extracellular matrix patterning in Drosophila melanogaster. PMID:18245854
An investigation of heterochromatin domains on the fourth chromosome of Drosophila melanogaster. PMID:18245350
A Drosophila gain-of-function screen for candidate genes involved in steroid-dependent neuroendocrine cell remodeling. PMID:18245346
Mutations in the Drosophila mitochondrial tRNA amidotransferase, bene/gatA, cause growth defects in mitotic and endoreplicating tissues. PMID:18245325
Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling. PMID:18243100
Drosophila Pxt: a cyclooxygenase-like facilitator of follicle maturation. PMID:18216169
rosy Function is required for juvenile hormone effects in Drosophila melanogaster. PMID:18202373
Enhancer blocking and transvection at the Drosophila apterous locus. PMID:18202363
Reduced body weight is a common effect of gene knockout in mice. PMID:18182103
Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles. PMID:18158335
Genome organization and gene expression shape the transposable element distribution in the Drosophila melanogaster euchromatin. PMID:18081425
Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging. PMID:18078670
A glial amino-acid transporter controls synapse strength and courtship in Drosophila. PMID:18066061
Insertional mutagenesis strategies in zebrafish. PMID:18047701
Retroviral enhancer detection insertions in zebrafish combined with comparative genomics reveal genomic regulatory blocks - a fundamental feature of vertebrate genomes. PMID:18047696
The DNA transposon Minos as a tool for transgenesis and functional genomic analysis in vertebrates and invertebrates. PMID:18047694
Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives. PMID:18047686
Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. PMID:17973985
The hermes transposon of Musca domestica is an efficient tool for the mutagenesis of Schizosaccharomyces pombe. PMID:17947404
The ribosomal protein genes and Minute loci of Drosophila melanogaster. PMID:17927810
X chromosome inactivation during Drosophila spermatogenesis. PMID:17927450
Genomewide clonal analysis of lethal mutations in the Drosophila melanogaster eye: comparison of the X chromosome and autosomes. PMID:17720911
Quantitative genomics of locomotor behavior in Drosophila melanogaster. PMID:17708775
Control of a kinesin-cargo linkage mechanism by JNK pathway kinases. PMID:17658258
Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells. PMID:17637833
Propagation of olfactory information in Drosophila. PMID:17596338
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. PMID:17569867
New candidate genes for sex-comb divergence between Drosophila mauritiana and Drosophila simulans. PMID:17565959
Experimental selection for Drosophila survival in extremely low O(2) environment. PMID:17534440
Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1. PMID:17519021
Multiple functions of Drosophila BLM helicase in maintenance of genome stability. PMID:17507683
Screen for dominant behavioral mutations caused by genomic insertion of P-element transposons in Drosophila: an examination of the integration of viral vector sequences. PMID:17464796
Peptides encoded by short ORFs control development and define a new eukaryotic gene family. PMID:17439302
Mutations in cytochrome c oxidase subunit VIa cause neurodegeneration and motor dysfunction in Drosophila. PMID:17435251
The early developmental gene Semaphorin 5c contributes to olfactory behavior in adult Drosophila. PMID:17435226
Thirty-one flavors of Drosophila rab proteins. PMID:17409086
Genomic regulatory blocks encompass multiple neighboring genes and maintain conserved synteny in vertebrates. PMID:17387144
Cutoff and aubergine mutations result in retrotransposon upregulation and checkpoint activation in Drosophila. PMID:17363252
A Drosophila melanogaster model of spinal muscular atrophy reveals a function for SMN in striated muscle. PMID:17353360
An essential role for Drosophila hus1 in somatic and meiotic DNA damage responses. PMID:17327271
Functional interactions between the Moses corepressor and DHR78 nuclear receptor regulate growth in Drosophila. PMID:17322404
The flamenco locus controls the gypsy and ZAM retroviruses and is required for Drosophila oogenesis. PMID:17277359
Nonvesicular release of glutamate by glial xCT transporters suppresses glutamate receptor clustering in vivo. PMID:17202478
The carnegie protein trap library: a versatile tool for Drosophila developmental studies. PMID:17194782
Exploring strategies for protein trapping in Drosophila. PMID:17179094
Drosophila SPF45: a bifunctional protein with roles in both splicing and DNA repair. PMID:17154718
Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity. PMID:17132048
A genetic screen in Drosophila for genes interacting with senseless during neuronal development identifies the importin moleskin. PMID:17110483
An efficient promoter trap for detection of patterned gene expression and subsequent functional analysis in Drosophila. PMID:17093046
Hypersensitivity to oxygen and shortened lifespan in a Drosophila mitochondrial complex II mutant. PMID:17056719
Transcriptional response to alcohol exposure in Drosophila melanogaster. PMID:17054780
Quantitative genomics of aggressive behavior in Drosophila melanogaster. PMID:17044737
Heat-shock promoters: targets for evolution by P transposable elements in Drosophila. PMID:17029562
Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. PMID:17028343
Functional characterization of Drosophila Translin and Trax. PMID:17028328
DRONC coordinates cell death and compensatory proliferation. PMID:16980627
The FERM protein Yurt is a negative regulatory component of the Crumbs complex that controls epithelial polarity and apical membrane size. PMID:16950127
One hundred years of high-throughput Drosophila research. PMID:16821132
Quantitative trait loci for locomotor behavior in Drosophila melanogaster. PMID:16783013
High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster. PMID:16702433
A Drosophila model of oculopharyngeal muscular dystrophy reveals intrinsic toxicity of PABPN1. PMID:16642034
Drosophila Eph receptor guides specific axon branches of mushroom body neurons. PMID:16613832
Drosophila RhoGAP68F is a putative GTPase activating protein for RhoA participating in gastrulation. PMID:16609869
The Drosophila P68 RNA helicase regulates transcriptional deactivation by promoting RNA release from chromatin. PMID:16598038
Remarkable site specificity of local transposition into the Hsp70 promoter of Drosophila melanogaster. PMID:16582443
U7 snRNA mutations in Drosophila block histone pre-mRNA processing and disrupt oogenesis. PMID:16495235
The nicotinic acetylcholine receptor Dalpha7 is required for an escape behavior in Drosophila. PMID:16494528
Genome-wide P-element screen for Drosophila synaptogenesis mutants. PMID:16408305
Analysis of pyrimidine catabolism in Drosophila melanogaster using epistatic interactions with mutations of pyrimidine biosynthesis and beta-alanine metabolism. PMID:16361227
Increased synaptic microtubules and altered synapse development in Drosophila sec8 mutants. PMID:16351720
Gain-of-function screen for genes that affect Drosophila muscle pattern formation. PMID:16254604
Vibrio cholerae infection of Drosophila melanogaster mimics the human disease cholera. PMID:16201020
Two distinct domains in Drosophila melanogaster telomeres. PMID:16143601
A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones. PMID:16129837
Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control. PMID:16107559
The 4.1 protein coracle mediates subunit-selective anchoring of Drosophila glutamate receptors to the postsynaptic actin cytoskeleton. PMID:16014728
Gene expression during Drosophila wing morphogenesis and differentiation. PMID:15998724
Genes involved in Drosophila glutamate receptor expression and localization. PMID:15985179
Minos as a genetic and genomic tool in Drosophila melanogaster. PMID:15972463
Locomotion defects, together with Pins, regulates heterotrimeric G-protein signaling during Drosophila neuroblast asymmetric divisions. PMID:15937221
Target-selected mutant screen by TILLING in Drosophila. PMID:15867432
Genetics and genomics of Drosophila mating behavior. PMID:15851659
Chriz, a chromodomain protein specific for the interbands of Drosophila melanogaster polytene chromosomes. PMID:15821938
Sequence elements in cis influence heterochromatic silencing in trans. PMID:15601858
Systematic gene targeting on the X chromosome of Drosophila melanogaster. PMID:15480728
A reverse genetic screen in Drosophila using a deletion-inducing mutagen. PMID:15461801
aubergine mutations in Drosophila melanogaster impair P cytotype determination by telomeric P elements inserted in heterochromatin. PMID:15372228
The Drosophila receptor guanylyl cyclase Gyc76C is required for semaphorin-1a-plexin A-mediated axonal repulsion. PMID:15282266
MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes PubMed citations: 323.

323 articles citing: MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes

Intact Drosophila central nervous system cellular quantitation reveals sexual dimorphism. PMID:35801638
Extended disordered regions of ribosome-associated NAC proteins paralogs belong only to the germline in Drosophila melanogaster. PMID:35778515
An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. PMID:35723254
γ-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor. PMID:35654038
Genetic regulation of central synapse formation and organization in Drosophila melanogaster. PMID:35652253
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. PMID:35502740
Drosophila Tet Is Required for Maintaining Glial Homeostasis in Developing and Adult Fly Brains. PMID:35396259
The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity. PMID:35373908
An Expanding Toolkit for Heterochromatin Repair Studies. PMID:35328082
A role for Flower and cell death in controlling morphogen gradient scaling. PMID:35301437
Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases. PMID:35294868
Sidekick dynamically rebalances contractile and protrusive forces to control tissue morphogenesis. PMID:35258563
Loss-of-function variants in TIAM1 are associated with developmental delay, intellectual disability, and seizures. PMID:35240055
New resources for the Drosophila 4th chromosome: FRT101F enabled mitotic clones and Bloom syndrome helicase enabled meiotic recombination. PMID:35084488
The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth. PMID:35037619
A protein-trap allele reveals roles for Drosophila ATF4 in photoreceptor degeneration, oogenesis and wing development. PMID:34919148
Mutants of the white ABCG Transporter in Drosophila melanogaster Have Deficient Olfactory Learning and Cholesterol Homeostasis. PMID:34884779
bfc, a novel serpent co-factor for the expression of croquemort, regulates efferocytosis in Drosophila melanogaster. PMID:34860835
Bioinformatic and cell-based tools for pooled CRISPR knockout screening in mosquitos. PMID:34819517
DAAM mediates the assembly of long-lived, treadmilling stress fibers in collectively migrating epithelial cells in Drosophila. PMID:34812144
Bi-allelic variants in OGDHL cause a neurodevelopmental spectrum disease featuring epilepsy, hearing loss, visual impairment, and ataxia. PMID:34800363
Pvr and distinct downstream signaling factors are required for hemocyte spreading and epidermal wound closure at Drosophila larval wound sites. PMID:34751396
Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc. PMID:34750371
An ELISA-based method for rapid genetic screens in Drosophila. PMID:34686600
Constructing and Tuning Excitatory Cholinergic Synapses: The Multifaceted Functions of Nicotinic Acetylcholine Receptors in Drosophila Neural Development and Physiology. PMID:34650404
Slo2/KNa Channels in Drosophila Protect against Spontaneous and Induced Seizure-like Behavior Associated with an Increased Persistent Na+ Current. PMID:34544836
Multiplexed drug-based selection and counterselection genetic manipulations in Drosophila. PMID:34525356
A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation. PMID:34492006
Application of Fluorescent Proteins for Functional Dissection of the Drosophila Visual System. PMID:34445636
Msps governs acentrosomal microtubule assembly and reactivation of quiescent neural stem cells. PMID:34368973
Proliferative stem cells maintain quiescence of their niche by secreting the Activin inhibitor Follistatin. PMID:34363758
Optogenetic approaches for understanding homeostatic and degenerative processes in Drosophila. PMID:34232330
The Serine Protease Homolog, Scarface, Is Sensitive to Nutrient Availability and Modulates the Development of the Drosophila Blood-Brain Barrier. PMID:34210781
Sex-Differences in Traumatic Brain Injury in the Absence of Tau in Drosophila. PMID:34198629
Cell-type-specific, multicolor labeling of endogenous proteins with split fluorescent protein tags in Drosophila. PMID:34074768
Temporal regulation of nicotinic acetylcholine receptor subunits supports central cholinergic synapse development in Drosophila. PMID:34074746
Loss of Fis1 impairs proteostasis during skeletal muscle aging in Drosophila. PMID:34061429
Hox dosage contributes to flight appendage morphology in Drosophila. PMID:34001903
Slit/Robo Signaling Regulates Multiple Stages of the Development of the Drosophila Motion Detection System. PMID:33968921
Response of the microbiome-gut-brain axis in Drosophila to amino acid deficit. PMID:33953396
An insulator blocks access to enhancers by an illegitimate promoter, preventing repression by transcriptional interference. PMID:33901190
Receptors and Channels Associated with Alcohol Use: Contributions from Drosophila. PMID:33870197
Rare deleterious de novo missense variants in Rnf2/Ring2 are associated with a neurodevelopmental disorder with unique clinical features. PMID:33864376
Scarless engineering of the Drosophila genome near any site-specific integration site. PMID:33772309
Methods and tools for spatial mapping of single-cell RNAseq clusters in Drosophila. PMID:33713129
Glial insulin regulates cooperative or antagonistic Golden goal/Flamingo interactions during photoreceptor axon guidance. PMID:33666170
Investigating rare and ultrarare epilepsy syndromes with Drosophila models. PMID:33659928
Investigation of Drosophila fruitless neurons that express Dpr/DIP cell adhesion molecules. PMID:33616528
Histone lysine methyltransferase Pr-set7/SETD8 promotes neural stem cell reactivation. PMID:33565211
Preserving transcriptional stress responses as an anti-aging strategy. PMID:33474790
Octopaminergic neurons have multiple targets in Drosophila larval mushroom body calyx and can modulate behavioral odor discrimination. PMID:33452115
The Cytoplasmic LIM Domain Protein Espinas Contributes to Photoreceptor Layer Selection in the Visual System. PMID:33327397
Magnesium efflux from Drosophila Kenyon cells is critical for normal and diet-enhanced long-term memory. PMID:33242000
The Drosophila Split Gal4 System for Neural Circuit Mapping. PMID:33240047
BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms. PMID:33232675
Stac protein regulates release of neuropeptides. PMID:33168737
teiresias, a Fruitless target gene encoding an immunoglobulin-superfamily transmembrane protein, is required for neuronal feminization in Drosophila. PMID:33087851
Conditional protein tagging methods reveal highly specific subcellular distribution of ion channels in motion-sensing neurons. PMID:33079061
A Neural Basis for Categorizing Sensory Stimuli to Enhance Decision Accuracy. PMID:33065003
Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception in Drosophila. PMID:33028630
Rosy Beginnings: Studying Peroxisomes in Drosophila. PMID:32984330
Defining the Boundaries of Polycomb Domains in Drosophila. PMID:32948625
Glial Metabolic Rewiring Promotes Axon Regeneration and Functional Recovery in the Central Nervous System. PMID:32941799
Drosophila Voltage-Gated Sodium Channels Are Only Expressed in Active Neurons and Are Localized to Distal Axonal Initial Segment-like Domains. PMID:32928889
Proximity-dependent labeling methods for proteomic profiling in living cells: An update. PMID:32909689
Frizzled-Dependent Planar Cell Polarity without Secreted Wnt Ligands. PMID:32888416
Serotonergic modulation of visual neurons in Drosophila melanogaster. PMID:32866139
A cell atlas of adult muscle precursors uncovers early events in fibre-type divergence in Drosophila. PMID:32815271
Different functions of two putative Drosophila α2δ subunits in the same identified motoneurons. PMID:32792569
Differentiating Drosophila female germ cells initiate Polycomb silencing by regulating PRC2-interacting proteins. PMID:32773039
Attenuation of epigenetic regulator SMARCA4 and ERK-ETS signaling suppresses aging-related dopaminergic degeneration. PMID:32749068
Selective Disruption of Synaptic BMP Signaling by a Smad Mutation Adjacent to the Highly Conserved H2 Helix. PMID:32737119
Damage-responsive, maturity-silenced enhancers regulate multiple genes that direct regeneration in Drosophila. PMID:32490812
A biallelic pathogenic variant in the OGDH gene results in a neurological disorder with features of a mitochondrial disease. PMID:32383294
A single-cell atlas of adult Drosophila ovary identifies transcriptional programs and somatic cell lineage regulating oogenesis. PMID:32339165
Basigin Associates with Integrin in Order to Regulate Perineurial Glia and Drosophila Nervous System Morphology. PMID:32265259
A combinatorial code of transcription factors specifies subtypes of visual motion-sensing neurons in Drosophila. PMID:32238425
The fruitless gene affects female receptivity and species isolation. PMID:32208837
Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation. PMID:32156755
A Toll-receptor map underlies structural brain plasticity. PMID:32066523
Targeted De Novo Centromere Formation in Drosophila Reveals Plasticity and Maintenance Potential of CENP-A Chromatin. PMID:32049040
Embryonic geometry underlies phenotypic variation in decanalized conditions. PMID:32048988
The mirtron miR-1010 functions in concert with its host gene SKIP to balance elevation of nAcRβ2. PMID:32015391
Antioxidant Therapy in Parkinson's Disease: Insights from Drosophila melanogaster. PMID:31936094
Steroid Hormone Entry into the Brain Requires a Membrane Transporter in Drosophila. PMID:31928869
Molecular characterization and distribution of the voltage-gated sodium channel, Para, in the brain of the grasshopper and vinegar fly. PMID:31902005
Muscarinic Modulation of Antennal Lobe GABAergic Local Neurons Shapes Odor Coding and Behavior. PMID:31801087
Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly. PMID:31735666
Protein trap: a new Swiss army knife for geneticists? PMID:31728729
Nitric oxide acts as a cotransmitter in a subset of dopaminergic neurons to diversify memory dynamics. PMID:31724947
Modular transcriptional programs separately define axon and dendrite connectivity. PMID:31687928
An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. PMID:31674908
Bi-allelic Variants in IQSEC1 Cause Intellectual Disability, Developmental Delay, and Short Stature. PMID:31607425
Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. PMID:31597093
Coordination between stochastic and deterministic specification in the Drosophila visual system. PMID:31582524
Semaphorin 2b Regulates Sleep-Circuit Formation in the Drosophila Central Brain. PMID:31564592
Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary. PMID:31558581
Drosophila Bruton's Tyrosine Kinase Regulates Habituation Latency and Facilitation in Distinct Mushroom Body Neurons. PMID:31530645
Using Drosophila Models and Tools to Understand the Mechanisms of Novel Human Cancer Driver Gene Function. PMID:31520347
Drosophila Model in Cancer: An Introduction. PMID:31520346
Muscarinic acetylcholine receptor signaling generates OFF selectivity in a simple visual circuit. PMID:31501438
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila. PMID:31498321
Drosophila ClC-a is required in glia of the stem cell niche for proper neurogenesis and wiring of neural circuits. PMID:31479171
Sidekick Is a Key Component of Tricellular Adherens Junctions that Acts to Resolve Cell Rearrangements. PMID:31353315
Calmodulin-binding transcription factor shapes the male courtship song in Drosophila. PMID:31344027
The miRNA bantam regulates growth and tumorigenesis by repressing the cell cycle regulator tribbles. PMID:31331981
The fruit fly at the interface of diagnosis and pathogenic mechanisms of rare and common human diseases. PMID:31227826
Inhibitory muscarinic acetylcholine receptors enhance aversive olfactory learning in adult Drosophila. PMID:31215865
Drosophila Tet Is Expressed in Midline Glia and Is Required for Proper Axonal Development. PMID:31213988
Rapid Evolution of Gained Essential Developmental Functions of a Young Gene via Interactions with Other Essential Genes. PMID:31187122
Flip-flop Mediated Conditional Gene Inactivation in Drosophila. PMID:31179351
In vivo study of gene expression with an enhanced dual-color fluorescent transcriptional timer. PMID:31140975
Different Evolutionary Trajectories of Two Insect-Specific Paralogous Proteins Involved in Stabilizing Muscle Myofibrils. PMID:31123042
Studying alcohol use disorder using Drosophila melanogaster in the era of 'Big Data'. PMID:30992041
A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo. PMID:30917109
Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS. PMID:30912745
One-trial learning in larval Drosophila. PMID:30898973
A modular toolset of phiC31-based fluorescent protein tagging vectors for Drosophila. PMID:30885036
The development and assembly of the Drosophila adult ventral nerve cord. PMID:30826502
Oriented Cell Divisions Are Not Required for Drosophila Wing Shape. PMID:30799243
Drosophila ZDHHC8 palmitoylates scribble and Ras64B and controls growth and viability. PMID:30735487
The Drosophila fussel gene is required for bitter gustatory neuron differentiation acting within an Rpd3 dependent chromatin modifying complex. PMID:30730884
Functionalisation of Virus-Like Particles Enhances Antitumour Immune Responses. PMID:30729137
Transsynaptic interactions between IgSF proteins DIP-α and Dpr10 are required for motor neuron targeting specificity. PMID:30714906
Stereotyped terminal axon branching of leg motor neurons mediated by IgSF proteins DIP-α and Dpr10. PMID:30714901
Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch. PMID:30642837
Imaging Flies by Fluorescence Microscopy: Principles, Technologies, and Applications. PMID:30626639
Mapping Neurotransmitter Identity in the Whole-Mount Drosophila Brain Using Multiplex High-Throughput Fluorescence in Situ Hybridization. PMID:30563859
Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila. PMID:30539716
Interactions between the Ig-Superfamily Proteins DIP-α and Dpr6/10 Regulate Assembly of Neural Circuits. PMID:30467079
Distinct Roles for Peroxisomal Targeting Signal Receptors Pex5 and Pex7 in Drosophila. PMID:30389805
Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster. PMID:30341464
Pleiotropy of the Drosophila melanogaster foraging gene on larval feeding-related traits. PMID:30303018
Bi-allelic Loss-of-Function Variants in DNMBP Cause Infantile Cataracts. PMID:30290152
Functional characterization of the three Drosophila retinal degeneration C (RDGC) protein phosphatase isoforms. PMID:30265717
Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila. PMID:30247122
The CCHamide1 Neuropeptide Expressed in the Anterior Dorsal Neuron 1 Conveys a Circadian Signal to the Ventral Lateral Neurons in Drosophila melanogaster. PMID:30246807
DARPins recognizing mTFP1 as novel reagents for in vitro and in vivo protein manipulations. PMID:30237292
The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception. PMID:30231996
The transcription factor SoxD controls neuronal guidance in the Drosophila visual system. PMID:30190506
Ret and Substrate-Derived TGF-β Maverick Regulate Space-Filling Dendrite Growth in Drosophila Sensory Neurons. PMID:30157422
Stepwise wiring of the Drosophila olfactory map requires specific Plexin B levels. PMID:30136927
Experience-dependent structural plasticity targets dynamic filopodia in regulating dendrite maturation and synaptogenesis. PMID:30135566
Combinations of DIPs and Dprs control organization of olfactory receptor neuron terminals in Drosophila. PMID:30102700
An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila. PMID:30091705
Drosophila CaV2 channels harboring human migraine mutations cause synapse hyperexcitability that can be suppressed by inhibition of a Ca2+ store release pathway. PMID:30080864
IRF2BPL Is Associated with Neurological Phenotypes. PMID:30057031
Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases. PMID:30030826
Reconfiguration of a Multi-oscillator Network by Light in the Drosophila Circadian Clock. PMID:29910074
A biophysical mechanism for preferred direction enhancement in fly motion vision. PMID:29897917
Lgl reduces endosomal vesicle acidification and Notch signaling by promoting the interaction between Vap33 and the V-ATPase complex. PMID:29871910
Diversification of heart progenitor cells by EGF signaling and differential modulation of ETS protein activity. PMID:29869981
Using Drosophila to study mechanisms of hereditary hearing loss. PMID:29853544
Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder. PMID:29726930
Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms. PMID:29689197
The POU/Oct Transcription Factor Nubbin Controls the Balance of Intestinal Stem Cell Maintenance and Differentiation by Isoform-Specific Regulation. PMID:29681543
An RNAi Screen Identifies New Genes Required for Normal Morphogenesis of Larval Chordotonal Organs. PMID:29678948
Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila. PMID:29669801
Efficient Expression of Genes in the Drosophila Germline Using a UAS Promoter Free of Interference by Hsp70 piRNAs. PMID:29669732
Dstac is required for normal circadian activity rhythms in Drosophila. PMID:29621409
Engineering the Drosophila Genome for Developmental Biology. PMID:29615571
Genome-wide analysis of gene regulation mechanisms during Drosophila spermatogenesis. PMID:29609617
A gene-specific T2A-GAL4 library for Drosophila. PMID:29565247
Robust ΦC31-Mediated Genome Engineering in Drosophila melanogaster Using Minimal attP/attB Phage Sites. PMID:29523637
Neurexin and Neuroligin-based adhesion complexes drive axonal arborisation growth independent of synaptic activity. PMID:29504935
Nubbin isoform antagonism governs Drosophila intestinal immune homeostasis. PMID:29499056
Feedback inhibition of actin on Rho mediates content release from large secretory vesicles. PMID:29496739
A kinase-dependent feedforward loop affects CREBB stability and long term memory formation. PMID:29473541
In Vivo Imaging of Muscle-tendon Morphogenesis in Drosophila Pupae. PMID:29443094
Drosophila: An Emergent Model for Delineating Interactions between the Circadian Clock and Drugs of Abuse. PMID:29391952
Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses. PMID:29379112
Aminode: Identification of Evolutionary Constraints in the Human Proteome. PMID:29358731
Chaski, a novel Drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional stress. PMID:29352169
The apical scaffold big bang binds to spectrins and regulates the growth of Drosophila melanogaster wing discs. PMID:29326287
Copper and Zinc Homeostasis: Lessons from Drosophila melanogaster. PMID:29312444
Recurrent Circuitry for Balancing Sleep Need and Sleep. PMID:29307711
Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance. PMID:29307555
The ABC Transporter Eato Promotes Cell Clearance in the Drosophila melanogaster Ovary. PMID:29295819
Genotype Influences Day-to-Day Variability in Sleep in Drosophila melanogaster. PMID:29228366
Coupling optogenetics and light-sheet microscopy, a method to study Wnt signaling during embryogenesis. PMID:29192250
Neuromodulatory connectivity defines the structure of a behavioral neural network. PMID:29165248
Dissection and Immunofluorescent Staining of Mushroom Body and Photoreceptor Neurons in Adult Drosophila melanogaster Brains. PMID:29155751
A versatile genetic tool for post-translational control of gene expression in Drosophila melanogaster. PMID:29140243
Genetic strategies to tackle neurological diseases in fruit flies. PMID:29128849
Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells. PMID:29123099
Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis. PMID:29114039
Opbp is a new architectural/insulator protein required for ribosomal gene expression. PMID:29036346
The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila. PMID:29032244
Combinatorial action of Grainyhead, Extradenticle and Notch in regulating Hox mediated apoptosis in Drosophila larval CNS. PMID:29023471
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila. PMID:28978772
The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D. PMID:28965825
Retrograde semaphorin-plexin signalling drives homeostatic synaptic plasticity. PMID:28953869
Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104. PMID:28925357
The mushroom body D1 dopamine receptor controls innate courtship drive. PMID:28902472
Neuronal Machinery of Sleep Homeostasis in Drosophila. PMID:28898631
Extended Synaptotagmin Localizes to Presynaptic ER and Promotes Neurotransmission and Synaptic Growth in Drosophila. PMID:28882990
Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research. PMID:28874452
Drosophila Nociceptive Sensitization Requires BMP Signaling via the Canonical SMAD Pathway. PMID:28855331
Deconstruction of the beaten Path-Sidestep interaction network provides insights into neuromuscular system development. PMID:28829740
A common directional tuning mechanism of Drosophila motion-sensing neurons in the ON and in the OFF pathway. PMID:28829040
Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe. PMID:28827667
The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling. PMID:28753614
Decoding temporal interpretation of the morphogen Bicoid in the early Drosophila embryo. PMID:28691901
Taking Stock of the Drosophila Research Ecosystem. PMID:28684603
Fibroblast growth factor signaling instructs ensheathing glia wrapping of Drosophila olfactory glomeruli. PMID:28674010
The laminar organization of the Drosophila ellipsoid body is semaphorin-dependent and prevents the formation of ectopic synaptic connections. PMID:28632130
On chip cryo-anesthesia of Drosophila larvae for high resolution in vivo imaging applications. PMID:28613308
Vibrio cholerae ensures function of host proteins required for virulence through consumption of luminal methionine sulfoxide. PMID:28586382
A cell cycle-independent, conditional gene inactivation strategy for differentially tagging wild-type and mutant cells. PMID:28561736
Hormone-dependent control of developmental timing through regulation of chromatin accessibility. PMID:28536147
Yorkie regulates epidermal wound healing in Drosophila larvae independently of cell proliferation and apoptosis. PMID:28514643
Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc. PMID:28512185
Representations of Novelty and Familiarity in a Mushroom Body Compartment. PMID:28502772
Interaction Between Familial Transmission and a Constitutively Active Immune System Shapes Gut Microbiota in Drosophila melanogaster. PMID:28413160
Cell-matrix adhesion and cell-cell adhesion differentially control basal myosin oscillation and Drosophila egg chamber elongation. PMID:28406187
Proximity-dependent labeling methods for proteomic profiling in living cells. PMID:28387482
Testis-specific ATP synthase peripheral stalk subunits required for tissue-specific mitochondrial morphogenesis in Drosophila. PMID:28335714
The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals. PMID:28331029
FlpStop, a tool for conditional gene control in Drosophila. PMID:28211790
Transgenic line for the identification of cholinergic release sites in Drosophila melanogaster. PMID:28167805
Bxb1 phage recombinase assists genome engineering in Drosophila melanogaster. PMID:28118814
Precision Optogenetic Tool for Selective Single- and Multiple-Cell Ablation in a Live Animal Model System. PMID:28065655
Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. PMID:28017472
A Syndromic Neurodevelopmental Disorder Caused by De Novo Variants in EBF3. PMID:28017372
Neural Circuits Underlying Fly Larval Locomotion. PMID:27928962
Serotonergic Modulation Differentially Targets Distinct Network Elements within the Antennal Lobe of Drosophila melanogaster. PMID:27845422
FlyBase at 25: looking to the future. PMID:27799470
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. PMID:27795562
Zasp52, a Core Z-disc Protein in Drosophila Indirect Flight Muscles, Interacts with α-Actinin via an Extended PDZ Domain. PMID:27783625
Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes. PMID:27737911
The Drosophila formin Fhos is a primary mediator of sarcomeric thin-filament array assembly. PMID:27731794
The Q-System: A Versatile Expression System for Drosophila. PMID:27730575
Distinct combinations of variant ionotropic glutamate receptors mediate thermosensation and hygrosensation in Drosophila. PMID:27656904
Failure to Burrow and Tunnel Reveals Roles for jim lovell in the Growth and Endoreplication of the Drosophila Larval Tracheae. PMID:27494251
Cell-type-specific profiling of protein-DNA interactions without cell isolation using targeted DamID with next-generation sequencing. PMID:27490632
A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin. PMID:27474442
Editing Transgenic DNA Components by Inducible Gene Replacement in Drosophila melanogaster. PMID:27334272
The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. PMID:27331610
Staccato/Unc-13-4 controls secretory lysosome-mediated lumen fusion during epithelial tube anastomosis. PMID:27323327
Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors. PMID:27292797
PiggyBac transposon-based polyadenylation-signal trap for genome-wide mutagenesis in mice. PMID:27292714
A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function. PMID:27280787
Targeted genetics in Drosophila cell lines: Inserting single transgenes in vitro. PMID:27261098
The Enok acetyltransferase complex interacts with Elg1 and negatively regulates PCNA unloading to promote the G1/S transition. PMID:27198229
A rapid, gentle and scalable method for dissociation and fluorescent sorting of imaginal disc cells for mRNA sequencing. PMID:27057746
Building a ladder to Hershey Heaven. PMID:27023744
Genetic Dissociation of Daily Sleep and Sleep Following Thermogenetic Sleep Deprivation in Drosophila. PMID:26951392
A genome-wide resource for the analysis of protein localisation in Drosophila. PMID:26896675
Dscam Proteins Direct Dendritic Targeting through Adhesion. PMID:26844831
SPARC-Dependent Cardiomyopathy in Drosophila. PMID:26839388
A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction. PMID:26815659
An Indexed, Mapped Mutant Library Enables Reverse Genetics Studies of Biological Processes in Chlamydomonas reinhardtii. PMID:26764374
Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins. PMID:26687361
Ig Superfamily Ligand and Receptor Pairs Expressed in Synaptic Partners in Drosophila. PMID:26687360
The Wiggle Index: An Open Source Bioassay to Assess Sub-Lethal Insecticide Response in Drosophila melanogaster. PMID:26684454
Curly Encodes Dual Oxidase, Which Acts with Heme Peroxidase Curly Su to Shape the Adult Drosophila Wing. PMID:26587980
Genetics on the Fly: A Primer on the Drosophila Model System. PMID:26564900
The Splice Isoforms of the Drosophila Ecdysis Triggering Hormone Receptor Have Developmentally Distinct Roles. PMID:26534952
Histone H3 Threonine Phosphorylation Regulates Asymmetric Histone Inheritance in the Drosophila Male Germline. PMID:26522592
Establishment of a Developmental Compartment Requires Interactions between Three Synergistic Cis-regulatory Modules. PMID:26468882
Specification of Dendritogenesis Site in Drosophila aCC Motoneuron by Membrane Enrichment of Pak1 through Dscam1. PMID:26460947
Genome engineering: Drosophila melanogaster and beyond. PMID:26447401
Localization of Hippo signalling complexes and Warts activation in vivo. PMID:26420589
Morgan's legacy: fruit flies and the functional annotation of conserved genes. PMID:26406362
Dynamic regulation of basement membrane protein levels promotes egg chamber elongation in Drosophila. PMID:26348027
Studying polyglutamine diseases in Drosophila. PMID:26257024
A genetic toolkit for tagging intronic MiMIC containing genes. PMID:26102525
Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila adipocytes. PMID:26090908
Drosophila Gyf/GRB10 interacting GYF protein is an autophagy regulator that controls neuron and muscle homeostasis. PMID:26086452
An effector Peptide family required for Drosophila toll-mediated immunity. PMID:25915418
The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer. PMID:25840432
A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila. PMID:25824290
Alternative mechanisms for talin to mediate integrin function. PMID:25754646
Plug-and-play genetic access to drosophila cell types using exchangeable exon cassettes. PMID:25732830
Gene-specific cell labeling using MiMIC transposons. PMID:25712101
Matrix metalloproteinase 2 is required for ovulation and corpus luteum formation in Drosophila. PMID:25695427
Fruit flies in biomedical research. PMID:25624315
Versatile genetic paintbrushes: Brainbow technologies. PMID:25491327
Aurora kinases phosphorylate Lgl to induce mitotic spindle orientation in Drosophila epithelia. PMID:25484300
Signaling by the engulfment receptor draper: a screen in Drosophila melanogaster implicates cytoskeletal regulators, Jun N-terminal Kinase, and Yorkie. PMID:25395664
Strategies for gene disruption in Drosophila. PMID:25364499
Regulation of synaptic development and function by the Drosophila PDZ protein Dyschronic. PMID:25359729
A versatile two-step CRISPR- and RMCE-based strategy for efficient genome engineering in Drosophila. PMID:25324299
Survival of the fittest tools. PMID:25316776
Fast and efficient Drosophila melanogaster gene knock-ins using MiMIC transposons. PMID:25298537
Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. PMID:25294943
Ultrafast tissue staining with chemical tags. PMID:25157152
RNAi screening comes of age: improved techniques and complementary approaches. PMID:25145850
Rapid clearance of epigenetic protein reporters from wound edge cells in Drosophila larvae does not depend on the JNK or PDGFR/VEGFR signaling pathways. PMID:25114797
The Drosophila F-box protein Fbxl7 binds to the protocadherin fat and regulates Dachs localization and Hippo signaling. PMID:25107277
Damage signals in the insect immune response. PMID:25071815
Cytoskeletal tension inhibits Hippo signaling through an Ajuba-Warts complex. PMID:24995985
Target organ specific activity of drosophila MRP (ABCC1) moderates developmental toxicity of methylmercury. PMID:24863968
The Little Fly that Could: Wizardry and Artistry of Drosophila Genomics. PMID:24827974
The conserved transmembrane proteoglycan Perdido/Kon-tiki is essential for myofibrillogenesis and sarcomeric structure in Drosophila. PMID:24794494
Resources for functional genomics studies in Drosophila melanogaster. PMID:24653003
Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster. PMID:24583113
Neuronal machinery of sleep homeostasis in Drosophila. PMID:24559676
Cell-type-specific labeling of synapses in vivo through synaptic tagging with recombination. PMID:24462095
Inducible protein traps with dominant phenotypes for functional analysis of the Drosophila genome. PMID:24172131
Accelerated homologous recombination and subsequent genome modification in Drosophila. PMID:24154526
Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase. PMID:24048591
Noninvasive analysis of microbiome dynamics in the fruit fly Drosophila melanogaster. PMID:24014528
The conserved ADAMTS-like protein lonely heart mediates matrix formation and cardiac tissue integrity. PMID:23874219
An extracellular interactome of immunoglobulin and LRR proteins reveals receptor-ligand networks. PMID:23827685
A method to test a chromosomal regulatory element in vivo by its substitutive address insertion into the basic transgenic construct preliminarily integrated into the genome. PMID:23824462
Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging. PMID:23819996
TRACER: a resource to study the regulatory architecture of the mouse genome. PMID:23547943
Essential role of grim-led programmed cell death for the establishment of corazonin-producing peptidergic nervous system during embryogenesis and metamorphosis in Drosophila melanogaster. PMID:23519152
Misshapen decreases integrin levels to promote epithelial motility and planar polarity in Drosophila. PMID:23509067
An Incompatibility between a mitochondrial tRNA and its nuclear-encoded tRNA synthetase compromises development and fitness in Drosophila. PMID:23382693
Multiple interactions control synaptic layer specificity in the Drosophila visual system. PMID:23352166
Captured segment exchange: a strategy for custom engineering large genomic regions in Drosophila melanogaster. PMID:23150604
Long-range targeted manipulation of the Drosophila genome by site-specific integration and recombinational resolution. PMID:23150601
The genetic analysis of functional connectomics in Drosophila. PMID:23084874
Gene density, transcription, and insulators contribute to the partition of the Drosophila genome into physical domains. PMID:23041285
Ectopic assembly of heterochromatin in Drosophila melanogaster triggered by transposable elements. PMID:22891327
A modular toolset for recombination transgenesis and neurogenetic analysis of Drosophila. PMID:22848718
A novel approach for directing transgene expression in Drosophila: T2A-Gal4 in-frame fusion. PMID:22209908
Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. PMID:22174071
Genetic manipulation of genes and cells in the nervous system of the fruit fly. PMID:22017985
Reconfiguring gene traps for new tasks using iTRAC. PMID:22004889
'MiMICing' genomic flexibility. PMID:21878919
The Drosophila gene disruption project: progress using transposons with distinctive site specificities PubMed citations: 187.

187 articles citing: The Drosophila gene disruption project: progress using transposons with distinctive site specificities

Development of Transformation for Genome Editing of an Emerging Model Organism. PMID:35885891
The Transposition Rate Has Little Influence on the Plateauing Level of the P-element. PMID:35731857
An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. PMID:35723254
Conserved function of Drosophila Fancd2 monoubiquitination in response to double-strand DNA breaks. PMID:35595243
Knockdown of a Cyclic Nucleotide-Gated Ion Channel Impairs Locomotor Activity and Recovery From Hypoxia in Adult Drosophila melanogaster. PMID:35530504
Identification of additional dye tracers for measuring solid food intake and food preference via consumption-excretion in Drosophila. PMID:35418664
Drosophila centrocortin is dispensable for centriole duplication but contributes to centrosome separation. PMID:35100335
New resources for the Drosophila 4th chromosome: FRT101F enabled mitotic clones and Bloom syndrome helicase enabled meiotic recombination. PMID:35084488
Synergistic epistasis of the deleterious effects of transposable elements. PMID:34888644
The Drosophila anterior-posterior axis is polarized by asymmetric myosin activation. PMID:34856125
Expression of human HIPKs in Drosophila demonstrates their shared and unique functions in a developmental model. PMID:34849772
An ELISA-based method for rapid genetic screens in Drosophila. PMID:34686600
Phosphatidylserine synthase plays an essential role in glia and affects development, as well as the maintenance of neuronal function. PMID:34401677
Large Drosophila germline piRNA clusters are evolutionarily labile and dispensable for transposon regulation. PMID:34352205
Miniature neurotransmission is required to maintain Drosophila synaptic structures during ageing. PMID:34285221
Physical and Chemical Barriers in the Larval Midgut Confer Developmental Resistance to Virus Infection in Drosophila. PMID:34065985
Read between the Lines: Diversity of Nontranslational Selection Pressures on Local Codon Usage. PMID:33944930
Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals. PMID:33828169
Natural variation in the regulation of neurodevelopmental genes modifies flight performance in Drosophila. PMID:33735180
An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance. PMID:33693600
Mayday sustains trans-synaptic BMP signaling required for synaptic maintenance with age. PMID:33667157
Optogenetics in Drosophila. PMID:33398822
Identification of Genes Contributing to a Long Circadian Period in Drosophila Melanogaster. PMID:33274675
BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms. PMID:33232675
FreeClimber: automated quantification of climbing performance in Drosophila. PMID:33188065
Using Drosophila melanogaster To Discover Human Disease Genes: An Educational Primer for Use with "Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target". PMID:33158986
Role of the Mitochondrial Pyruvate Carrier in the Occurrence of Metabolic Inflexibility in Drosophila melanogaster Exposed to Dietary Sucrose. PMID:33066485
Metabolic Characterization and Consequences of Mitochondrial Pyruvate Carrier Deficiency in Drosophila melanogaster. PMID:32899962
Emerging mechanisms of cell competition. PMID:32778819
speck, First Identified in Drosophila melanogaster in 1910, Is Encoded by the Arylalkalamine N-Acetyltransferase (AANAT1) Gene. PMID:32709620
Double-edged sword: The evolutionary consequences of the epigenetic silencing of transposable elements. PMID:32673310
GWAS for Lifespan and Decline in Climbing Ability in Flies upon Dietary Restriction Reveal decima as a Mediator of Insulin-like Peptide Production. PMID:32502405
Transposable elements employ distinct integration strategies with respect to transcriptional landscapes in eukaryotic genomes. PMID:32442316
Fine-Scale Position Effects Shape the Distribution of Inversion Breakpoints in Drosophila melanogaster. PMID:32437518
Biallelic mutations in SORD cause a common and potentially treatable hereditary neuropathy with implications for diabetes. PMID:32367058
Temperature and Sweet Taste Integration in Drosophila. PMID:32330421
Antioxidant Therapy in Parkinson's Disease: Insights from Drosophila melanogaster. PMID:31936094
Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation. PMID:31913420
Advances in high-throughput methods for the identification of virus receptors. PMID:31865406
Protein trap: a new Swiss army knife for geneticists? PMID:31728729
Gene Knock-Ins in Drosophila Using Homology-Independent Insertion of Universal Donor Plasmids. PMID:31685521
A ribosomal protein S5 isoform is essential for oogenesis and interacts with distinct RNAs in Drosophila melanogaster. PMID:31551467
Using Drosophila Models and Tools to Understand the Mechanisms of Novel Human Cancer Driver Gene Function. PMID:31520347
Drosophila Model in Cancer: An Introduction. PMID:31520346
Pharmaco-Genetic Screen To Uncover Actin Regulators Targeted by Prostaglandins During Drosophila Oogenesis. PMID:31506320
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila. PMID:31498321
The Drosophila ERG channel seizure plays a role in the neuronal homeostatic stress response. PMID:31393878
Common and distinct transcriptional signatures of mammalian embryonic lethality. PMID:31243271
Intellectual disability and autism spectrum disorders 'on the fly': insights from Drosophila. PMID:31088981
An Interscholastic Network To Generate LexA Enhancer Trap Lines in Drosophila. PMID:31040111
eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS. PMID:31023341
Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach. PMID:30803481
The peacefulness gene promotes aggression in Drosophila. PMID:30606245
Cytokine exocytosis and JAK/STAT activation in the Drosophila ovary requires the vesicle trafficking regulator α-Snap. PMID:30404830
Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster. PMID:30341464
The Evolution of Small-RNA-Mediated Silencing of an Invading Transposable Element. PMID:30252073
Model organism data evolving in support of translational medicine. PMID:30224793
Structural Variants and Selective Sweep Foci Contribute to Insecticide Resistance in the Drosophila Genetic Reference Panel. PMID:30190421
An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila. PMID:30091705
The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization. PMID:30037897
A Cyclin E Centered Genetic Network Contributes to Alcohol-Induced Variation in Drosophila Development. PMID:29871898
In vivo bioassay to test the pathogenicity of missense human AIP variants. PMID:29632148
Wingless Signaling: A Genetic Journey from Morphogenesis to Metastasis. PMID:29618590
A gene-specific T2A-GAL4 library for Drosophila. PMID:29565247
Drosophila Sidekick is required in developing photoreceptors to enable visual motion detection. PMID:29361567
The ABC Transporter Eato Promotes Cell Clearance in the Drosophila melanogaster Ovary. PMID:29295819
Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep. PMID:29240764
Genotype Influences Day-to-Day Variability in Sleep in Drosophila melanogaster. PMID:29228366
How well do you know your mutation? Complex effects of genetic background on expressivity, complementation, and ordering of allelic effects. PMID:29166655
Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome. PMID:29097652
The road less traveled: from genotype to phenotype in flies and humans. PMID:29058036
Dissecting the Role of the Extracellular Matrix in Heart Disease: Lessons from the Drosophila Genetic Model. PMID:29056683
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila. PMID:28978772
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics. PMID:28953874
Neuronal Machinery of Sleep Homeostasis in Drosophila. PMID:28898631
From Peas to Disease: Modifier Genes, Network Resilience, and the Genetics of Health. PMID:28777930
Taking Stock of the Drosophila Research Ecosystem. PMID:28684603
Genetics of alcohol consumption in Drosophila melanogaster. PMID:28627812
Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons. PMID:28606304
The Genetic Architecture of Ovariole Number in Drosophila melanogaster: Genes with Major, Quantitative, and Pleiotropic Effects. PMID:28550012
Specification and spatial arrangement of cells in the germline stem cell niche of the Drosophila ovary depend on the Maf transcription factor Traffic jam. PMID:28542174
Glutamate Is a Wake-Active Neurotransmitter in Drosophila melanogaster. PMID:28364503
The Drosophila DAXX-Like Protein (DLP) Cooperates with ASF1 for H3.3 Deposition and Heterochromatin Formation. PMID:28320872
Genetics and genomics of alcohol responses in Drosophila. PMID:28161376
Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits. PMID:28151408
Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration. PMID:28139767
Multidrug transporters and organic anion transporting polypeptides protect insects against the toxic effects of cardenolides. PMID:28011348
The ATP-sensitive K channel is seizure protective and required for effective dietary therapy in a model of mitochondrial encephalomyopathy. PMID:27868454
Genetic and Genomic Response to Selection for Food Consumption in Drosophila melanogaster. PMID:27704301
Mutation of orthologous prickle genes causes a similar epilepsy syndrome in flies and humans. PMID:27648459
Whole-Genome Sequencing and iPLEX MassARRAY Genotyping Map an EMS-Induced Mutation Affecting Cell Competition in Drosophila melanogaster. PMID:27574103
Analysis of PBase Binding Profile Indicates an Insertion Target Selection Mechanism Dependent on TTAA, But Not Transcriptional Activity. PMID:27570481
A Drosophila LexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research. PMID:27527793
lolal Is an Evolutionarily New Epigenetic Regulator of dpp Transcription during Dorsal-Ventral Axis Formation. PMID:27401231
Targeted genetics in Drosophila cell lines: Inserting single transgenes in vitro. PMID:27261098
Shank Modulates Postsynaptic Wnt Signaling to Regulate Synaptic Development. PMID:27225771
The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling. PMID:27223326
DNA Transposition at Work. PMID:27187082
Hybrid Dysgenesis in Drosophila simulans Associated with a Rapid Invasion of the P-Element. PMID:26982327
Testing candidate genes for attention-deficit/hyperactivity disorder in fruit flies using a high throughput assay for complex behavior. PMID:26954609
Genetic Dissociation of Daily Sleep and Sleep Following Thermogenetic Sleep Deprivation in Drosophila. PMID:26951392
FlyBase portals to human disease research using Drosophila models. PMID:26935103
The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster. PMID:26859824
Genome ARTIST: a robust, high-accuracy aligner tool for mapping transposon insertions and self-insertions. PMID:26855675
Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4(+) T Cells. PMID:26755332
Genetics on the Fly: A Primer on the Drosophila Model System. PMID:26564900
A Stochastic Burst Follows the Periodic Morning Peak in Individual Drosophila Locomotion. PMID:26528813
Polymorphisms in early neurodevelopmental genes affect natural variation in alcohol sensitivity in adult drosophila. PMID:26503115
TRP and Rhodopsin Transport Depends on Dual XPORT ER Chaperones Encoded by an Operon. PMID:26456832
Identification of Drosophila Mutants Affecting Defense to an Entomopathogenic Fungus. PMID:26202798
P Transposable Elements in Drosophila and other Eukaryotic Organisms. PMID:26104714
A genetic toolkit for tagging intronic MiMIC containing genes. PMID:26102525
Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior. PMID:26100892
Drosophila Rif1 is an essential gene and controls late developmental events by direct interaction with PP1-87B. PMID:26022086
It's more than stamp collecting: how genome sequencing can unify biological research. PMID:26003218
Genome-Wide Association Analyses Point to Candidate Genes for Electric Shock Avoidance in Drosophila melanogaster. PMID:25992709
The recent invasion of natural Drosophila simulans populations by the P-element. PMID:25964349
Neto-mediated intracellular interactions shape postsynaptic composition at the Drosophila neuromuscular junction. PMID:25905467
Ih channels control feedback regulation from amacrine cells to photoreceptors. PMID:25831426
A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila. PMID:25824290
Controlled expression of Drosophila homeobox loci using the Hostile takeover system. PMID:25820349
Drosophila and experimental neurology in the post-genomic era. PMID:25814441
Generating customized transgene landing sites and multi-transgene arrays in Drosophila using phiC31 integrase. PMID:25680812
FMRFamide signaling promotes stress-induced sleep in Drosophila. PMID:25668617
Identification of genes that promote or inhibit olfactory memory formation in Drosophila. PMID:25644700
Fruit flies in biomedical research. PMID:25624315
Ecdysone response gene E78 controls ovarian germline stem cell niche formation and follicle survival in Drosophila. PMID:25624267
Tethering of SUUR and HP1 proteins results in delayed replication of euchromatic regions in Drosophila melanogaster polytene chromosomes. PMID:25398563
Signaling by the engulfment receptor draper: a screen in Drosophila melanogaster implicates cytoskeletal regulators, Jun N-terminal Kinase, and Yorkie. PMID:25395664
Strategies for gene disruption in Drosophila. PMID:25364499
Survival of the fittest tools. PMID:25316776
Analysis of the expression patterns, subcellular localisations and interaction partners of Drosophila proteins using a pigP protein trap library. PMID:25294943
piRNA clusters and open chromatin structure. PMID:25126116
Rapid clearance of epigenetic protein reporters from wound edge cells in Drosophila larvae does not depend on the JNK or PDGFR/VEGFR signaling pathways. PMID:25114797
Peroxisomes are required for lipid metabolism and muscle function in Drosophila melanogaster. PMID:24945818
Generation of a transgenic ORFeome library in Drosophila. PMID:24922270
Multifunctional RNA processing protein SRm160 induces apoptosis and regulates eye and genital development in Drosophila. PMID:24907259
Malaria vaccines: high-throughput tools for antigens discovery with potential for their development. PMID:24892459
Contrasting influences of Drosophila white/mini-white on ethanol sensitivity in two different behavioral assays. PMID:24890118
The Little Fly that Could: Wizardry and Artistry of Drosophila Genomics. PMID:24827974
Genomic landscape of human, bat, and ex vivo DNA transposon integrations. PMID:24809961
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines. PMID:24714809
Resources for functional genomics studies in Drosophila melanogaster. PMID:24653003
Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster. PMID:24583113
Neuronal machinery of sleep homeostasis in Drosophila. PMID:24559676
Transgenic Anopheles gambiae expressing an antimalarial peptide suffer no significant fitness cost. PMID:24516671
Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11. PMID:24492843
Detection of sweet tastants by a conserved group of insect gustatory receptors. PMID:24474785
Large-scale mapping of transposable element insertion sites using digital encoding of sample identity. PMID:24374352
Postsynaptic glutamate receptors regulate local BMP signaling at the Drosophila neuromuscular junction. PMID:24353060
DNA transposon-based gene vehicles - scenes from an evolutionary drive. PMID:24320156
Epistasis and quantitative traits: using model organisms to study gene-gene interactions. PMID:24296533
Large conserved domains of low DNA methylation maintained by Dnmt3a. PMID:24270360
Small RNAs, big impact: small RNA pathways in transposon control and their effect on the host stress response. PMID:24254230
Inducible protein traps with dominant phenotypes for functional analysis of the Drosophila genome. PMID:24172131
Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. PMID:24067533
Mushroom body miscellanea: transgenic Drosophila strains expressing anatomical and physiological sensor proteins in Kenyon cells. PMID:24065891
Requirement for commissureless2 function during dipteran insect nerve cord development. PMID:24026811
Genetic modifier screens to identify components of a redox-regulated cell adhesion and migration pathway. PMID:23849867
Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system. PMID:23827738
A method to test a chromosomal regulatory element in vivo by its substitutive address insertion into the basic transgenic construct preliminarily integrated into the genome. PMID:23824462
The million mutation project: a new approach to genetics in Caenorhabditis elegans. PMID:23800452
Small-molecule screen in adult Drosophila identifies VMAT as a regulator of sleep. PMID:23658190
Genome-wide association study of sleep in Drosophila melanogaster. PMID:23617951
Enhancer trap infidelity in Drosophila optomotor-blind. PMID:23519069
Next-generation site-directed transgenesis in the malaria vector mosquito Anopheles gambiae: self-docking strains expressing germline-specific phiC31 integrase. PMID:23516619
Polycomb group response elements in Drosophila and vertebrates. PMID:23419717
The piggyBac transposon displays local and distant reintegration preferences and can cause mutations at noncanonical integration sites. PMID:23358416
Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior. PMID:23277560
A hormone receptor-based transactivator bridges different binary systems to precisely control spatial-temporal gene expression in Drosophila. PMID:23239992
Fife, a Drosophila Piccolo-RIM homolog, promotes active zone organization and neurotransmitter release. PMID:23197698
The Control of semaphorin-1a-mediated reverse signaling by opposing pebble and RhoGAPp190 functions in drosophila. PMID:23177958
Long-range targeted manipulation of the Drosophila genome by site-specific integration and recombinational resolution. PMID:23150601
Gene density, transcription, and insulators contribute to the partition of the Drosophila genome into physical domains. PMID:23041285
Drosophila models of tauopathies: what have we learned? PMID:22701808
Tissue, cell type and stage-specific ectopic gene expression and RNAi induction in the Drosophila testis. PMID:22553486
Drosophila Neto is essential for clustering glutamate receptors at the neuromuscular junction. PMID:22499592
Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. PMID:22496853
Exploiting Drosophila genetics to understand microRNA function and regulation. PMID:22365740
P-element homing is facilitated by engrailed polycomb-group response elements in Drosophila melanogaster. PMID:22276200
Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. PMID:22174071
Genetic manipulation of genes and cells in the nervous system of the fruit fly. PMID:22017985
Reconfiguring gene traps for new tasks using iTRAC. PMID:22004889
MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes. PMID:21985007
Drosophila P elements preferentially transpose to replication origins. PMID:21896744
Molecular genetic analyses of polytene chromosome region 72A-D in Drosophila melanogaster reveal a gene desert in 72D. PMID:21853143
Dynamic interactions between transposable elements and their hosts. PMID:21850042
A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila PubMed citations: 161.

161 articles citing: A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. PMID:35723254
An RNA-immunoprecipitation protocol to identify RNAs associated with RNA-binding proteins in cytoplasmic and nuclear Drosophila head fractions. PMID:35634357
Integrin-ECM interactions and membrane-associated Catalase cooperate to promote resilience of the Drosophila intestinal epithelium. PMID:35522719
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. PMID:35502740
Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases. PMID:35294868
Loss-of-function variants in TIAM1 are associated with developmental delay, intellectual disability, and seizures. PMID:35240055
New resources for the Drosophila 4th chromosome: FRT101F enabled mitotic clones and Bloom syndrome helicase enabled meiotic recombination. PMID:35084488
Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling. PMID:35044823
In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor. PMID:35020877
A protein-trap allele reveals roles for Drosophila ATF4 in photoreceptor degeneration, oogenesis and wing development. PMID:34919148
Distinct molecular pathways govern presynaptic homeostatic plasticity. PMID:34910905
Frazzled/Dcc acts independently of Netrin to promote germline survival during Drosophila oogenesis. PMID:34910816
Mutants of the white ABCG Transporter in Drosophila melanogaster Have Deficient Olfactory Learning and Cholesterol Homeostasis. PMID:34884779
Autocrine inhibition by a glutamate-gated chloride channel mediates presynaptic homeostatic depression. PMID:34851664
A Novel Neuron-Specific Regulator of the V-ATPase in Drosophila. PMID:34620624
A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation. PMID:34492006
GFP-Tagged Protein Detection by Electron Microscopy Using a GBP-APEX Tool in Drosophila. PMID:34476234
Coordination among multiple receptor tyrosine kinase signals controls Drosophila developmental timing and body size. PMID:34469735
Misregulation of Drosophila Sidestep Leads to Uncontrolled Wiring of the Adult Neuromuscular System and Severe Locomotion Defects. PMID:34149366
Sleep deprivation results in diverse patterns of synaptic scaling across the Drosophila mushroom bodies. PMID:34107302
The steroid-hormone ecdysone coordinates parallel pupariation neuromotor and morphogenetic subprograms via epidermis-to-neuron Dilp8-Lgr3 signal induction. PMID:34099654
Cell-type-specific, multicolor labeling of endogenous proteins with split fluorescent protein tags in Drosophila. PMID:34074768
Temporal regulation of nicotinic acetylcholine receptor subunits supports central cholinergic synapse development in Drosophila. PMID:34074746
Characterizing dopaminergic neuron vulnerability using genome-wide analysis. PMID:34038543
Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling. PMID:33893307
Rare deleterious de novo missense variants in Rnf2/Ring2 are associated with a neurodevelopmental disorder with unique clinical features. PMID:33864376
Transneuronal Dpr12/DIP-δ interactions facilitate compartmentalized dopaminergic innervation of Drosophila mushroom body axons. PMID:33847376
RNAi-Mediated Silencing of Pgants Shows Core 1 O-Glycans Are Required for Pupation in Tribolium castaneum. PMID:33841170
Scarless engineering of the Drosophila genome near any site-specific integration site. PMID:33772309
Methods and tools for spatial mapping of single-cell RNAseq clusters in Drosophila. PMID:33713129
Mayday sustains trans-synaptic BMP signaling required for synaptic maintenance with age. PMID:33667157
Investigation of Drosophila fruitless neurons that express Dpr/DIP cell adhesion molecules. PMID:33616528
Insulin signaling mediates neurodegeneration in glioma. PMID:33526430
Preserving transcriptional stress responses as an anti-aging strategy. PMID:33474790
Octopaminergic neurons have multiple targets in Drosophila larval mushroom body calyx and can modulate behavioral odor discrimination. PMID:33452115
The Cytoplasmic LIM Domain Protein Espinas Contributes to Photoreceptor Layer Selection in the Visual System. PMID:33327397
Conditional protein tagging methods reveal highly specific subcellular distribution of ion channels in motion-sensing neurons. PMID:33079061
Drosophila sperm development and intercellular cytoplasm sharing through ring canals do not require an intact fusome. PMID:33033119
Proximity-dependent labeling methods for proteomic profiling in living cells: An update. PMID:32909689
Cell-to-cell communication mediates glioblastoma progression in Drosophila. PMID:32878880
A Genetic Screen Links the Disease-Associated Nab2 RNA-Binding Protein to the Planar Cell Polarity Pathway in Drosophila melanogaster. PMID:32817074
A cell atlas of adult muscle precursors uncovers early events in fibre-type divergence in Drosophila. PMID:32815271
Different functions of two putative Drosophila α2δ subunits in the same identified motoneurons. PMID:32792569
Regulation of Trpm activation and calcium wave initiation during Drosophila egg activation. PMID:32735035
Intrinsic control of muscle attachment sites matching. PMID:32706334
The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription. PMID:32463833
The NMDA receptor regulates competition of epithelial cells in the Drosophila wing. PMID:32376880
Variants in CAPZA2, a member of an F-actin capping complex, cause intellectual disability and developmental delay. PMID:32338762
Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain. PMID:32286230
Basigin Associates with Integrin in Order to Regulate Perineurial Glia and Drosophila Nervous System Morphology. PMID:32265259
Unc-4 acts to promote neuronal identity and development of the take-off circuit in the Drosophila CNS. PMID:32216875
Sertraline induces DNA damage and cellular toxicity in Drosophila that can be ameliorated by antioxidants. PMID:32161356
Carrier of Wingless (Cow) Regulation of Drosophila Neuromuscular Junction Development. PMID:32024666
A genetic, genomic, and computational resource for exploring neural circuit function. PMID:31939737
The neuropeptide Drosulfakinin regulates social isolation-induced aggression in Drosophila. PMID:31900346
Use of the CRISPR-Cas9 System in Drosophila Cultured Cells to Introduce Fluorescent Tags into Endogenous Genes. PMID:31869524
Distinct expression of potassium channels regulates visual response properties of lamina neurons in Drosophila melanogaster. PMID:31823004
Loss of Oxidation Resistance 1, OXR1, Is Associated with an Autosomal-Recessive Neurological Disease with Cerebellar Atrophy and Lysosomal Dysfunction. PMID:31785787
Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly. PMID:31735666
Protein trap: a new Swiss army knife for geneticists? PMID:31728729
An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. PMID:31674908
Electron transport chain biogenesis activated by a JNK-insulin-Myc relay primes mitochondrial inheritance in Drosophila. PMID:31612862
Bi-allelic Variants in IQSEC1 Cause Intellectual Disability, Developmental Delay, and Short Stature. PMID:31607425
Unintended perturbation of protein function using GFP nanobodies in human cells. PMID:31601614
Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. PMID:31597093
VIPERnano: Improved Live Cell Intracellular Protein Tracking. PMID:31545582
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila. PMID:31498321
Drosophila ClC-a is required in glia of the stem cell niche for proper neurogenesis and wiring of neural circuits. PMID:31479171
De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia. PMID:31327508
Reflections on the use of protein binders to study protein function in developmental biology. PMID:31265212
Flip-flop Mediated Conditional Gene Inactivation in Drosophila. PMID:31179351
A genetically encoded toolkit of functionalized nanobodies against fluorescent proteins for visualizing and manipulating intracellular signalling. PMID:31122229
Homeostatic scaling of active zone scaffolds maintains global synaptic strength. PMID:30914419
Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS. PMID:30912745
JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress. PMID:30735120
zGrad is a nanobody-based degron system that inactivates proteins in zebrafish. PMID:30735119
Transsynaptic interactions between IgSF proteins DIP-α and Dpr10 are required for motor neuron targeting specificity. PMID:30714906
Stereotyped terminal axon branching of leg motor neurons mediated by IgSF proteins DIP-α and Dpr10. PMID:30714901
Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch. PMID:30642837
Imaging Flies by Fluorescence Microscopy: Principles, Technologies, and Applications. PMID:30626639
Mapping Neurotransmitter Identity in the Whole-Mount Drosophila Brain Using Multiplex High-Throughput Fluorescence in Situ Hybridization. PMID:30563859
Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element. PMID:30476189
Transcriptional Regulation of Lipophorin Receptors Supports Neuronal Adaptation to Chronic Elevations of Activity. PMID:30380410
Bi-allelic Loss-of-Function Variants in DNMBP Cause Infantile Cataracts. PMID:30290152
Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila. PMID:30247122
The acyl-CoA Synthetase, pudgy, Promotes Sleep and Is Required for the Homeostatic Response to Sleep Deprivation. PMID:30186232
Conditional control of fluorescent protein degradation by an auxin-dependent nanobody. PMID:30120238
An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila. PMID:30091705
IRF2BPL Is Associated with Neurological Phenotypes. PMID:30057031
Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases. PMID:30030826
Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in Drosophila melanogaster. PMID:29925565
Lgl reduces endosomal vesicle acidification and Notch signaling by promoting the interaction between Vap33 and the V-ATPase complex. PMID:29871910
Using Drosophila to study mechanisms of hereditary hearing loss. PMID:29853544
Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder. PMID:29726930
Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms. PMID:29689197
Engineering the Drosophila Genome for Developmental Biology. PMID:29615571
A gene-specific T2A-GAL4 library for Drosophila. PMID:29565247
Functional analysis of the Drosophila RhoGAP Cv-c protein and its equivalence to the human DLC3 and DLC1 proteins. PMID:29545526
Nociceptive interneurons control modular motor pathways to promote escape behavior in Drosophila. PMID:29528286
Drosophila Fezf coordinates laminar-specific connectivity through cell-intrinsic and cell-extrinsic mechanisms. PMID:29513217
A kinase-dependent feedforward loop affects CREBB stability and long term memory formation. PMID:29473541
Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses. PMID:29379112
Copper and Zinc Homeostasis: Lessons from Drosophila melanogaster. PMID:29312444
A New Behavioral Test and Associated Genetic Tools Highlight the Function of Ventral Abdominal Muscles in Adult Drosophila. PMID:29209177
Development of a tissue-specific ribosome profiling approach in Drosophila enables genome-wide evaluation of translational adaptations. PMID:29194454
Neuromodulatory connectivity defines the structure of a behavioral neural network. PMID:29165248
Genetic strategies to tackle neurological diseases in fruit flies. PMID:29128849
Extending julius seizure, a bang-sensitive gene, as a model for studying epileptogenesis: Cold shock, and a new insertional mutation. PMID:29125376
Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis. PMID:29114039
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila. PMID:28978772
The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D. PMID:28965825
Prepatterning by RhoGEFs governs Rho GTPase spatiotemporal dynamics during wound repair. PMID:28923977
Extended Synaptotagmin Localizes to Presynaptic ER and Promotes Neurotransmission and Synaptic Growth in Drosophila. PMID:28882990
Model Organisms Facilitate Rare Disease Diagnosis and Therapeutic Research. PMID:28874452
Thioester-containing proteins regulate the Toll pathway and play a role in Drosophila defence against microbial pathogens and parasitoid wasps. PMID:28874153
The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling. PMID:28753614
Filamin actin-binding and titin-binding fulfill distinct functions in Z-disc cohesion. PMID:28732005
Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture. PMID:28716842
A genetic framework controlling the differentiation of intestinal stem cells during regeneration in Drosophila. PMID:28662029
A cell cycle-independent, conditional gene inactivation strategy for differentially tagging wild-type and mutant cells. PMID:28561736
PAR-1 promotes microtubule breakdown during dendrite pruning in Drosophila. PMID:28554895
Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc. PMID:28512185
A nanobody-based toolset to investigate the role of protein localization and dispersal in Drosophila. PMID:28395731
Proximity-dependent labeling methods for proteomic profiling in living cells. PMID:28387482
The developmental proteome of Drosophila melanogaster. PMID:28381612
Testis-specific ATP synthase peripheral stalk subunits required for tissue-specific mitochondrial morphogenesis in Drosophila. PMID:28335714
FlpStop, a tool for conditional gene control in Drosophila. PMID:28211790
Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling. PMID:28165006
Loss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. PMID:28017472
A Syndromic Neurodevelopmental Disorder Caused by De Novo Variants in EBF3. PMID:28017372
Transcriptome Analysis of Drosophila melanogaster Third Instar Larval Ring Glands Points to Novel Functions and Uncovers a Cytochrome p450 Required for Development. PMID:27974438
Drosophila Sulf1 is required for the termination of intestinal stem cell division during regeneration. PMID:27888216
FlyBase at 25: looking to the future. PMID:27799470
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. PMID:27795562
cAMP Signals in Drosophila Motor Neurons Are Confined to Single Synaptic Boutons. PMID:27783939
Somatic stem cell differentiation is regulated by PI3K/Tor signaling in response to local cues. PMID:27633989
Targeting protein function: the expanding toolkit for conditional disruption. PMID:27574023
Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. PMID:27338814
The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. PMID:27331610
Genome-Wide Approaches to Drosophila Heart Development. PMID:27294102
Early development of Drosophila embryos requires Smc5/6 function during oogenesis. PMID:27288507
A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function. PMID:27280787
Targeted genetics in Drosophila cell lines: Inserting single transgenes in vitro. PMID:27261098
Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination. PMID:27195754
DNA Transposition at Work. PMID:27187082
Building a ladder to Hershey Heaven. PMID:27023744
FlyBase portals to human disease research using Drosophila models. PMID:26935103
A genome-wide resource for the analysis of protein localisation in Drosophila. PMID:26896675
Rab8 directs furrow ingression and membrane addition during epithelial formation in Drosophila melanogaster. PMID:26839362
Accumulation of differentiating intestinal stem cell progenies drives tumorigenesis. PMID:26690827
Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins. PMID:26687361
Ig Superfamily Ligand and Receptor Pairs Expressed in Synaptic Partners in Drosophila. PMID:26687360
The Splice Isoforms of the Drosophila Ecdysis Triggering Hormone Receptor Have Developmentally Distinct Roles. PMID:26534952
A Follicle Rupture Assay Reveals an Essential Role for Follicular Adrenergic Signaling in Drosophila Ovulation. PMID:26473732
Genome engineering: Drosophila melanogaster and beyond. PMID:26447401
Morgan's legacy: fruit flies and the functional annotation of conserved genes. PMID:26406362
A genetic toolkit for tagging intronic MiMIC containing genes. PMID:26102525
Recognizing the importance of new tools and resources for research. PMID:25824292
Drosophila and experimental neurology in the post-genomic era. PMID:25814441
Plug-and-play genetic access to drosophila cell types using exchangeable exon cassettes. PMID:25732830
Gene-specific cell labeling using MiMIC transposons. PMID:25712101
A genetic toolkit for tagging intronic MiMIC containing genes PubMed citations: 61.

61 articles citing: A genetic toolkit for tagging intronic MiMIC containing genes

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. PMID:35723254
An RNA-immunoprecipitation protocol to identify RNAs associated with RNA-binding proteins in cytoplasmic and nuclear Drosophila head fractions. PMID:35634357
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. PMID:35502740
Loss-of-function variants in TIAM1 are associated with developmental delay, intellectual disability, and seizures. PMID:35240055
New resources for the Drosophila 4th chromosome: FRT101F enabled mitotic clones and Bloom syndrome helicase enabled meiotic recombination. PMID:35084488
The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth. PMID:35037619
A protein-trap allele reveals roles for Drosophila ATF4 in photoreceptor degeneration, oogenesis and wing development. PMID:34919148
Optogenetic approaches for understanding homeostatic and degenerative processes in Drosophila. PMID:34232330
Sleep deprivation results in diverse patterns of synaptic scaling across the Drosophila mushroom bodies. PMID:34107302
Investigation of Drosophila fruitless neurons that express Dpr/DIP cell adhesion molecules. PMID:33616528
Protein manipulation using single copies of short peptide tags in cultured cells and in Drosophila melanogaster. PMID:33593816
Neuron-Specific FMRP Roles in Experience-Dependent Remodeling of Olfactory Brain Innervation during an Early-Life Critical Period. PMID:33402421
The Cytoplasmic LIM Domain Protein Espinas Contributes to Photoreceptor Layer Selection in the Visual System. PMID:33327397
BICRA, a SWI/SNF Complex Member, Is Associated with BAF-Disorder Related Phenotypes in Humans and Model Organisms. PMID:33232675
Astroglial Calcium Signaling Encodes Sleep Need in Drosophila. PMID:33186550
Conditional protein tagging methods reveal highly specific subcellular distribution of ion channels in motion-sensing neurons. PMID:33079061
Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception in Drosophila. PMID:33028630
Drosophila Voltage-Gated Sodium Channels Are Only Expressed in Active Neurons and Are Localized to Distal Axonal Initial Segment-like Domains. PMID:32928889
Differentiating Drosophila female germ cells initiate Polycomb silencing by regulating PRC2-interacting proteins. PMID:32773039
The fruitless gene affects female receptivity and species isolation. PMID:32208837
Epigenetic Signaling in Glia Controls Presynaptic Homeostatic Plasticity. PMID:31810838
Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly. PMID:31735666
An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. PMID:31674908
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders. PMID:31616000
Bi-allelic Variants in IQSEC1 Cause Intellectual Disability, Developmental Delay, and Short Stature. PMID:31607425
Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. PMID:31597093
Understanding cellular signaling and systems biology with precision: A perspective from ultrastructure and organelle studies in the Drosophila midgut. PMID:31595264
Drosophila ClC-a is required in glia of the stem cell niche for proper neurogenesis and wiring of neural circuits. PMID:31479171
Flip-flop Mediated Conditional Gene Inactivation in Drosophila. PMID:31179351
Direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila. PMID:31019084
Expressional Profiling of Carpet Glia in the Developing Drosophila Eye Reveals Its Molecular Signature of Morphology Regulators. PMID:30983950
Lysosomal Machinery Drives Extracellular Acidification to Direct Non-apoptotic Cell Death. PMID:30943394
Transsynaptic interactions between IgSF proteins DIP-α and Dpr10 are required for motor neuron targeting specificity. PMID:30714906
Drosophila intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals. PMID:30404917
DARPins recognizing mTFP1 as novel reagents for in vitro and in vivo protein manipulations. PMID:30237292
An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila. PMID:30091705
Integration of Drosophila and Human Genetics to Understand Notch Signaling Related Diseases. PMID:30030826
Using Drosophila to study mechanisms of hereditary hearing loss. PMID:29853544
CORL Expression in the Drosophila Central Nervous System Is Regulated by Stage Specific Interactions of Intertwined Activators and Repressors. PMID:29848623
Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms. PMID:29689197
Efficient Expression of Genes in the Drosophila Germline Using a UAS Promoter Free of Interference by Hsp70 piRNAs. PMID:29669732
Engineering the Drosophila Genome for Developmental Biology. PMID:29615571
Introduction: Drosophila-A Model System for Developmental Biology. PMID:29615566
A gene-specific T2A-GAL4 library for Drosophila. PMID:29565247
highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models. PMID:29425495
Chinmo prevents transformer alternative splicing to maintain male sex identity. PMID:29389999
Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses. PMID:29379112
Biogenesis of zinc storage granules in Drosophila melanogaster. PMID:29367274
Copper and Zinc Homeostasis: Lessons from Drosophila melanogaster. PMID:29312444
Coupling optogenetics and light-sheet microscopy, a method to study Wnt signaling during embryogenesis. PMID:29192250
Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila. PMID:28978772
Ubiquitylation-independent activation of Notch signalling by Delta. PMID:28960177
The extracellular metalloprotease AdamTS-A anchors neural lineages in place within and preserves the architecture of the central nervous system. PMID:28760813
Taking Stock of the Drosophila Research Ecosystem. PMID:28684603
FlpStop, a tool for conditional gene control in Drosophila. PMID:28211790
FlyBase at 25: looking to the future. PMID:27799470
A simple method for imaging axonal transport in aging neurons using the adult Drosophila wing. PMID:27560175
The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. PMID:27331610
Ferritin Assembly in Enterocytes of Drosophila melanogaster. PMID:26861293
Tissue-specific tagging of endogenous loci in Drosophila melanogaster. PMID:26700726
Genome engineering: Drosophila melanogaster and beyond. PMID:26447401

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gene
metasource: Fairsharing.org
version: FAIRsharing.org: GDP Database; Gene Disruption Project Database ; DOI: https://doi.org/10.25504/FAIRsharing.6e05x2; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

transposable element
metasource: Fairsharing.org
version: FAIRsharing.org: GDP Database; Gene Disruption Project Database ; DOI: https://doi.org/10.25504/FAIRsharing.6e05x2; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

region
metasource: Fairsharing.org
version: FAIRsharing.org: GDP Database; Gene Disruption Project Database ; DOI: https://doi.org/10.25504/FAIRsharing.6e05x2; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:06 p.m.

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UET

Berkeley Drosophila Genome Project EST database

Berkeley Drosophila Genome Project insitu

Evolutionary Trace

Dfam

Berkeley Drosophila Transcription Network Project

FlyBase

Genome Project Database

REXdb

Candidate Cancer Gene Database

Eukaryotic Genes

GeneSigDB: a manually curated database and resource for analysis of gene expression signatures

GeneSigDB

TMC-SNPdb 2.0

Material Element

TRED - Transcriptional Regulatory Element Database

Regulatory Element Database for Drosophila

PROkariotIC Database Of Gene-Regulation

Drosophila developmental ontology

NCBI Gene