FlyAtlas 2
FlyAtlas 2 is the RNA-Seq successor to the original FlyAtlas (which was based on microarray analysis). Specifically, FlyAtlas 2 now provides access to: transcript information, sex-specific data for adult somatic tissues, and micro-RNA genes. FlyAtlas2 supports search by gene, category or tissue; and functionality has been improved through mobile support and the option to download results in spreadsheet format. Gene coverage has been extended by the inclusion of microRNAs and many of the RNA genes included in Release 6 of the Drosophila reference genome. The web interface has been modified to accommodate the extra data, but at the same time has been adapted for viewing on small mobile devices. Users also have access to the RNA-Seq reads displayed alongside the annotated Drosophila genome in the (external) UCSC browser, and are able to link out to the previous FlyAtlas resource to compare the data obtained by RNA-Seq with that obtained using microarrays.
Description
More detailed information about this field from each metasource.
FlyAtlas 2 is the RNA-Seq successor to the original FlyAtlas (which was based on microarray analysis). Specifically, FlyAtlas 2 now provides access to: transcript information, sex-specific data for adult somatic tissues, and micro-RNA genes. FlyAtlas2 supports search by gene, category or tissue; and functionality has been improved through mobile support and the option to download results in spreadsheet format. Gene coverage has been extended by the inclusion of microRNAs and many of the RNA genes included in Release 6 of the Drosophila reference genome. The web interface has been modified to accommodate the extra data, but at the same time has been adapted for viewing on small mobile devices. Users also have access to the RNA-Seq reads displayed alongside the annotated Drosophila genome in the (external) UCSC browser, and are able to link out to the previous FlyAtlas resource to compare the data obtained by RNA-Seq with that obtained using microarrays.
metasource: Fairsharing.orgversion: None
Webpage:
http://flyatlas.gla.ac.uk/FlyAtlas2/index.htmlWebpage
More detailed information about this field from each metasource.
http://flyatlas.gla.ac.uk/FlyAtlas2/index.html
metasource: Fairsharing.orgversion: None
http://www.flyatlas2.org
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Publications:
Publications
More detailed information about this field from each metasource.
Using FlyAtlas to identify better Drosophila melanogaster models of human disease
PMID: 17534367
metasource: Fairsharing.org
version: None
FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
PMID: 29069479
metasource: Fairsharing.org
version: None
FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster
PMID: 23203866
metasource: Fairsharing.org
version: None
http://dx.doi.org/10.1093/nar/gkx976
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
Using FlyAtlas to identify better Drosophila melanogaster models of human disease
PMID: 17534367
metasource: Fairsharing.org
version: None
FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
PMID: 29069479
metasource: Fairsharing.org
version: None
FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster
PMID: 23203866
metasource: Fairsharing.org
version: None
http://dx.doi.org/10.1093/nar/gkx976
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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Using FlyAtlas to identify better Drosophila melanogaster models of human disease
PubMed citations: 847.
847 articles citing: Using FlyAtlas to identify better Drosophila melanogaster models of human disease
Application of the 3C Method to Study the Developmental Genes in Drosophila Larvae. PMID:35910225
A Drosophila melanogaster model for TMEM43-related arrhythmogenic right ventricular cardiomyopathy type 5. PMID:35869176
Neuronal activity induces glucosylceramide that is secreted via exosomes for lysosomal degradation in glia. PMID:35857503
The red flour beetle T. castaneum: elaborate genetic toolkit and unbiased large scale RNAi screening to study insect biology and evolution. PMID:35854352
Drosophila Lipase 3 Mediates the Metabolic Response to Starvation and Aging. PMID:35821816
The E3 ligase Thin controls homeostatic plasticity through neurotransmitter release repression. PMID:35796533
RNAi-induced knockdown of white gene in the southern green stink bug (Nezara viridula L.). PMID:35729244
Global stable-isotope tracing metabolomics reveals system-wide metabolic alternations in aging Drosophila. PMID:35725845
Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing. PMID:35696569
Sex-specific variation in R-loop formation in Drosophila melanogaster. PMID:35687614
Interorgan communication through peripherally derived peptide hormones in Drosophila. PMID:35499154
Epistatic selection on a selfish Segregation Distorter supergene - drive, recombination, and genetic load. PMID:35486424
A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females. PMID:35471187
Drosophila melanogaster: a simple genetic model of kidney structure, function and disease. PMID:35411063
Modulation of RNA stability regulates gene expression in two opposite ways: through buffering of RNA levels upon global perturbations and by supporting adapted differential expression. PMID:35390159
The role of insulators and transcription in 3D chromatin organization of flies. PMID:35354608
ATP-sensitive inward rectifier potassium channels reveal functional linkage between salivary gland function and blood feeding in the mosquito, Aedes aegypti. PMID:35347209
"A fly appeared": sable, a classic Drosophila mutation, maps to Yippee, a gene affecting body color, wings, and bristles. PMID:35266526
FlyBase: a guided tour of highlighted features. PMID:35266522
CMTr cap-adjacent 2'-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses. PMID:35260552
Direct and indirect gene repression by the ecdysone cascade during mosquito reproductive cycle. PMID:35254892
Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly. PMID:35239393
Exploring the relevance of NUP93 variants in steroid-resistant nephrotic syndrome using next generation sequencing and a fly kidney model. PMID:35211795
Comparison of genome architecture at two stages of male germline cell differentiation in Drosophila. PMID:35166842
Improving one-step scarless genome editing in Drosophila melanogaster by combining ovoD co-CRISPR selection with sgRNA target site masking. PMID:35087953
TM2D genes regulate Notch signaling and neuronal function in Drosophila. PMID:34905536
Mutants of the white ABCG Transporter in Drosophila melanogaster Have Deficient Olfactory Learning and Cholesterol Homeostasis. PMID:34884779
Glitazone Treatment Rescues Phenotypic Deficits in a Fly Model of Gaucher/Parkinson's Disease. PMID:34884544
Nuclear transport genes recurrently duplicate by means of RNA intermediates in Drosophila but not in other insects. PMID:34863092
Temporal and sequential order of nonoverlapping gene networks unraveled in mated female Drosophila. PMID:34844981
The Fly Homologue of MFSD11 Is Possibly Linked to Nutrient Homeostasis and Has a Potential Role in Locomotion: A First Characterization of the Atypical Solute Carrier CG18549 in Drosophila Melanogaster. PMID:34821824
An explainable artificial intelligence approach for decoding the enhancer histone modifications code and identification of novel enhancers in Drosophila. PMID:34749786
FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas. PMID:34718735
Channel nuclear pore protein 54 directs sexual differentiation and neuronal wiring of female reproductive behaviors in Drosophila. PMID:34666772
A Novel Neuron-Specific Regulator of the V-ATPase in Drosophila. PMID:34620624
No Expression Divergence despite Transcriptional Interference between Nested Protein-Coding Genes in Mammals. PMID:34573363
Ion Channels in Epithelial Dynamics and Morphogenesis. PMID:34571929
Genomic organization of the autonomous regulatory domain of eyeless locus in Drosophila melanogaster. PMID:34570231
The gut-microbiota-brain axis in autism: what Drosophila models can offer? PMID:34525941
Cholecystokinin-like peptide mediates satiety by inhibiting sugar attraction. PMID:34398892
Expression of the foraging gene in adult Drosophila melanogaster. PMID:34382904
A Comparative Perspective on Functionally-Related, Intracellular Calcium Channels: The Insect Ryanodine and Inositol 1,4,5-Trisphosphate Receptors. PMID:34356655
A Personalized Therapeutics Approach Using an In Silico Drosophila Patient Model Reveals Optimal Chemo- and Targeted Therapy Combinations for Colorectal Cancer. PMID:34336681
Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila. PMID:34201304
Identification of Gonadulin and Insulin-Like Growth Factor From Migratory Locusts and Their Importance in Reproduction in Locusta migratoria. PMID:34177814
A combinatorial cis-regulatory logic restricts color-sensing Rhodopsins to specific photoreceptor subsets in Drosophila. PMID:34161320
Genotoxicity and cytotoxicity evaluation of two thallium compounds using the Drosophila wing somatic mutation and recombination test. PMID:34136682
Metabolically active and polyploid renal tissues rely on graded cytoprotection to drive developmental and homeostatic stress resilience. PMID:33913484
Proteomics of protein trafficking by in vivo tissue-specific labeling. PMID:33888706
Proteomics and ultrastructural analysis of Hermetia illucens (Diptera: Stratiomyidae) larval peritrophic matrix. PMID:33836751
Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. PMID:33819264
The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. PMID:33815151
The 40-Year Mystery of Insect Odorant-Binding Proteins. PMID:33808208
Exploiting the Potential of Drosophila Models in Lysosomal Storage Disorders: Pathological Mechanisms and Drug Discovery. PMID:33800050
Toward a Consensus in the Repertoire of Hemocytes Identified in Drosophila. PMID:33748138
Natural variation in the regulation of neurodevelopmental genes modifies flight performance in Drosophila. PMID:33735180
Leucokinin and Associated Neuropeptides Regulate Multiple Aspects of Physiology and Behavior in Drosophila. PMID:33669286
Assembly and Exploration of a Single Cell Atlas of the Drosophila Larval Ventral Cord. Identification of Rare Cell Types. PMID:33600085
Drosophila Sex Peptide controls the assembly of lipid microcarriers in seminal fluid. PMID:33495334
Increasing neuronal glucose uptake attenuates brain aging and promotes life span under dietary restriction in Drosophila. PMID:33490892
The Drosophila melanogaster Neprilysin Nepl15 is involved in lipid and carbohydrate storage. PMID:33483521
L-Carnitine in Drosophila: A Review. PMID:33371457
An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing. PMID:33257684
FlyBase: updates to the Drosophila melanogaster knowledge base. PMID:33219682
A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics. PMID:33170836
CG4928 Is Vital for Renal Function in Fruit Flies and Membrane Potential in Cells: A First In-Depth Characterization of the Putative Solute Carrier UNC93A. PMID:33163493
Genomic signatures of globally enhanced gene duplicate accumulation in the megadiverse higher Diptera fueling intralocus sexual conflict resolution. PMID:33083121
Chromosome separation during Drosophila male meiosis I requires separase-mediated cleavage of the homolog conjunction protein UNO. PMID:33001976
Nuclear translocation ability of Lipin differentially affects gene expression and survival in fed and fasting Drosophila. PMID:32989002
Gene-Level, but Not Chromosome-Wide, Divergence between a Very Young House Fly Proto-Y Chromosome and Its Homologous Proto-X Chromosome. PMID:32986844
Insulin and Leptin/Upd2 Exert Opposing Influences on Synapse Number in Fat-Sensing Neurons. PMID:32976758
Cellular metabolic reprogramming controls sugar appetite in Drosophila. PMID:32868922
Drosophila Insulin-Like Peptide 8 (DILP8) in Ovarian Follicle Cells Regulates Ovulation and Metabolism. PMID:32849266
Short neuropeptide F signaling regulates functioning of male reproductive system in Tenebrio molitor beetle. PMID:32749520
Polymorphism and Divergence of Novel Gene Expression Patterns in Drosophila melanogaster. PMID:32737121
Systemic and heart autonomous effects of sphingosine Δ4 desaturase deficiency in lipotoxic cardiac pathophysiology. PMID:32641420
Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development. PMID:32579612
Akirin proteins in development and disease: critical roles and mechanisms of action. PMID:32361777
Tissue-specific expression of ribosomal protein paralogue eRpL22-like in Drosophila melanogaster eye development. PMID:32353187
Drosophila NUAK functions with Starvin/BAG3 in autophagic protein turnover. PMID:32320396
Drosophila Middle-Term Memory: Amnesiac is Required for PKA Activation in the Mushroom Bodies, a Function Modulated by Neprilysin 1. PMID:32303647
The neuronal receptor tyrosine kinase Alk is a target for longevity. PMID:32291952
Concerted Actions of Octopamine and Dopamine Receptors Drive Olfactory Learning. PMID:32277043
Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. PMID:32183456
Rapid sex-specific adaptation to high temperature in Drosophila. PMID:32083552
NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models. PMID:32053595
How to turn an organism into a model organism in 10 'easy' steps. PMID:32034051
Physiology, Development, and Disease Modeling in the Drosophila Excretory System. PMID:32029579
CAPA neuropeptides and their receptor form an anti-diuretic hormone signaling system in the human disease vector, Aedes aegypti. PMID:32020001
Genomic organization of Polycomb Response Elements and its functional implication in Drosophila and other insects. PMID:31965990
A role for triglyceride lipase brummer in the regulation of sex differences in Drosophila fat storage and breakdown. PMID:31961851
Significance of DopEcR, a G-protein coupled dopamine/ecdysteroid receptor, in physiological and behavioral response to stressors. PMID:31955616
Specialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubule. PMID:31907321
The Drosophila Post-mating Response: Gene Expression and Behavioral Changes Reveal Perdurance and Variation in Cross-Tissue Interactions. PMID:31907222
Su(var)2-10 and the SUMO Pathway Link piRNA-Guided Target Recognition to Chromatin Silencing. PMID:31901446
Glycogen branching enzyme controls cellular iron homeostasis via Iron Regulatory Protein 1 and mitoNEET. PMID:31784520
Divergence in Transcriptional and Regulatory Responses to Mating in Male and Female Fruitflies. PMID:31695054
Drosophila Doublefault protein coordinates multiple events during male meiosis by controlling mRNA translation. PMID:31645358
Drosophila as a Model for Tumor-Induced Organ Wasting. PMID:31520356
Evidence for premature aging in a Drosophila model of Werner syndrome. PMID:31518666
Drift and Directional Selection Are the Evolutionary Forces Driving Gene Expression Divergence in Eye and Brain Tissue of Heliconius Butterflies. PMID:31467133
A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster. PMID:31415568
Positive Selection and Functional Divergence at Meiosis Genes That Mediate Crossing Over Across the Drosophila Phylogeny. PMID:31362974
A Secreted Ig-Domain Protein Required in Both Astrocytes and Neurons for Regulation of Drosophila Night Sleep. PMID:31353186
PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development. PMID:31327739
Screening of microRNAs controlling body fat in Drosophila melanogaster and identification of miR-969 and its target, Gr47b. PMID:31318925
Genome-Wide Association Analysis of Anoxia Tolerance in Drosophila melanogaster. PMID:31311780
ER-Ca2+ sensor STIM regulates neuropeptides required for development under nutrient restriction in Drosophila. PMID:31295329
Intestinal lipid droplets as novel mediators of host-pathogen interaction in Drosophila. PMID:31278163
Using genetic variation in Aedes aegypti to identify candidate anti-dengue virus genes. PMID:31272403
The Drosophila Malpighian tubule as a model for mammalian tubule function. PMID:31268918
Decreased Temperature Sensitivity of Vestigial Gene Expression in Temperate Populations of Drosophila melanogaster. PMID:31261809
Role of tbc1 in Drosophila embryonic salivary glands. PMID:31242864
Endocrine regulation of MFS2 by branchless controls phosphate excretion and stone formation in Drosophila renal tubules. PMID:31217461
Specialized eRpL22 paralogue-specific ribosomes regulate specific mRNA translation in spermatogenesis in Drosophila melanogaster. PMID:31188709
STRIPAK Members Orchestrate Hippo and Insulin Receptor Signaling to Promote Neural Stem Cell Reactivation. PMID:31167138
Mammalian Models of Traumatic Brain Injury and a Place for Drosophila in TBI Research. PMID:31105519
secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila. PMID:31097722
Patronin-mediated minus end growth is required for dendritic microtubule polarity. PMID:31076454
Characterisation of white and yellow eye colour mutant strains of house cricket, Acheta domesticus. PMID:31059541
Tools to reverse-engineer multicellular systems: case studies using the fruit fly. PMID:31049075
Molecular and genetic organization of bands and interbands in the dot chromosome of Drosophila melanogaster. PMID:31041520
Genome-wide sexually antagonistic variants reveal long-standing constraints on sexual dimorphism in fruit flies. PMID:31022179
A Comprehensive Drosophila melanogaster Transcription Factor Interactome. PMID:30995488
Adenine Methylation in Drosophila Is Associated with the Tissue-Specific Expression of Developmental and Regulatory Genes. PMID:30988038
Genome and Ontogenetic-Based Transcriptomic Analyses of the Flesh Fly, Sarcophaga bullata. PMID:30926723
Proteome changes in the aging Drosophila melanogaster head. PMID:30906200
Autophagy accounts for approximately one-third of mitochondrial protein turnover and is protein selective. PMID:30865561
Codon Usage Differences among Genes Expressed in Different Tissues of Drosophila melanogaster. PMID:30859203
Drosophila melanogaster tPlus3a and tPlus3b ensure full male fertility by regulating transcription of Y-chromosomal, seminal fluid, and heat shock genes. PMID:30845228
Identification of Essential Proteins Based on Improved HITS Algorithm. PMID:30823614
Sperm-Leucylaminopeptidases are required for male fertility as structural components of mitochondrial paracrystalline material in Drosophila melanogaster sperm. PMID:30802236
Behavioural and transcriptional changes in post-mating females of an egg parasitoid wasp species. PMID:30800387
Selection shapes turnover and magnitude of sex-biased expression in Drosophila gonads. PMID:30786879
Chromatin architecture reorganization during neuronal cell differentiation in Drosophila genome. PMID:30709849
RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stress. PMID:30651069
Re-annotation of eight Drosophila genomes. PMID:30599046
Composition of the Survival Motor Neuron (SMN) Complex in Drosophila melanogaster. PMID:30563832
Triacylglycerol Metabolism in Drosophila melanogaster. PMID:30523167
Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn2+ transporter. PMID:30520657
Retrograde BMP signaling activates neuronal gene expression through widespread deployment of a conserved BMP-responsive cis-regulatory activation element. PMID:30476189
Neuromuscular degeneration and locomotor deficit in a Drosophila model of mucopolysaccharidosis VII is attenuated by treatment with resveratrol. PMID:30459155
Modulation of Drosophila post-feeding physiology and behavior by the neuropeptide leucokinin. PMID:30457986
Deleterious mitochondrial DNA point mutations are overrepresented in Drosophila expressing a proofreading-defective DNA polymerase γ. PMID:30452458
The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a. PMID:30384843
Functional Consequences of the Evolution of Matrimony, a Meiosis-Specific Inhibitor of Polo Kinase. PMID:30351378
Pleiotropy of the Drosophila melanogaster foraging gene on larval feeding-related traits. PMID:30303018
Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster. PMID:30287514
Amnesiac Is Required in the Adult Mushroom Body for Memory Formation. PMID:30201766
Rationally-engineered reproductive barriers using CRISPR & CRISPRa: an evaluation of the synthetic species concept in Drosophila melanogaster. PMID:30177778
Systems level expression correlation of Ras GTPase regulators. PMID:30111366
Parallel Genomic Engineering of Two Drosophila Genes Using Orthogonal attB/attP Sites. PMID:30065043
Ras-ERK-ETS inhibition alleviates neuronal mitochondrial dysfunction by reprogramming mitochondrial retrograde signaling. PMID:30059502
A plant diterpene counteracts juvenile hormone-mediated gene regulation during Drosophila melanogaster larval development. PMID:30011330
Disruption of INOS, a Gene Encoding myo-Inositol Phosphate Synthase, Causes Male Sterility in Drosophila melanogaster. PMID:29991509
γ-TuRC Heterogeneity Revealed by Analysis of Mozart1. PMID:29983314
Gene Regulatory Variation in Drosophila melanogaster Renal Tissue. PMID:29976765
Dpp regulates autophagy-dependent midgut removal and signals to block ecdysone production. PMID:29959404
Genes Relocated Between Drosophila Chromosome Arms Evolve Under Relaxed Selective Constraints Relative to Non-Relocated Genes. PMID:29926120
Learning on the Fly: The Interplay between Caspases and Cancer. PMID:29854765
The importance of a halotyrosine dehalogenase for Drosophila fertility. PMID:29764939
Etiology and treatment of adrenoleukodystrophy: new insights from Drosophila. PMID:29739804
A Fly's Eye View of Natural and Drug Reward. PMID:29720947
Multivalency regulates activity in an intrinsically disordered transcription factor. PMID:29714690
Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms. PMID:29689197
Conservation of cardiac L-type Ca2+ channels and their regulation in Drosophila: A novel genetically-pliable channelopathic model. PMID:29684406
Genome-wide analysis of gene regulation mechanisms during Drosophila spermatogenesis. PMID:29609617
Assessment of Aedes albopictus reference genes for quantitative PCR at different stages of development. PMID:29554153
Ceramide-Protein Interactions Modulate Ceramide-Associated Lipotoxic Cardiomyopathy. PMID:29514098
L(3)mbt and the LINT complex safeguard cellular identity in the Drosophila ovary. PMID:29511022
An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion. PMID:29472725
Modeling the Role of Wnt Signaling in Human and Drosophila Stem Cells. PMID:29462894
The Molecular and Genetic Characterization of Second Chromosome Balancers in Drosophila melanogaster. PMID:29420191
Octopamine and Tyramine Contribute Separately to the Counter-Regulatory Response to Sugar Deficit in Drosophila. PMID:29379421
Inwardly Rectifying Potassium (Kir) Channels Represent a Critical Ion Conductance Pathway in the Nervous Systems of Insects. PMID:29371678
Drosophila melanogaster White Mutant w1118 Undergo Retinal Degeneration. PMID:29354028
Functional characterization of adaptive variation within a cis-regulatory element influencing Drosophila melanogaster growth. PMID:29324742
Evidence for a hierarchical transcriptional circuit in Drosophila male germline involving testis-specific TAF and two gene-specific transcription factors, Mod and Acj6. PMID:29235675
The Drosophila junctophilin gene is functionally equivalent to its four mammalian counterparts and is a modifier of a Huntingtin poly-Q expansion and the Notch pathway. PMID:29208631
Regulation of Carbohydrate Energy Metabolism in Drosophila melanogaster. PMID:29203701
Severe Fertility Effects of sheepish Sperm Caused by Failure To Enter Female Sperm Storage Organs in Drosophila melanogaster. PMID:29158336
Peptidergic control in a fruit crop pest: The spotted-wing drosophila, Drosophila suzukii. PMID:29125862
Insecticidal effects of dsRNA targeting the Diap1 gene in dipteran pests. PMID:29123201
Physiological characterization and regulation of the contractile properties of the mosquito ventral diverticulum (crop). PMID:29107658
Deletion of the nicotinic acetylcholine receptor subunit gene Dα1 confers insecticide resistance, but at what cost? PMID:29095106
Transforming Growth Factor β/Activin signaling in neurons increases susceptibility to starvation. PMID:29084242
FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data. PMID:29069479
Analysis of temporal transcription expression profiles reveal links between protein function and developmental stages of Drosophila melanogaster. PMID:29045400
Characterization of a set of abdominal neuroendocrine cells that regulate stress physiology using colocalized diuretic peptides in Drosophila. PMID:29043393
Roles of Female and Male Genotype in Post-Mating Responses in Drosophila melanogaster. PMID:29036644
Transcription-Associated Compositional Skews in Drosophila Genes. PMID:29036491
Few Nuclear-Encoded Mitochondrial Gene Duplicates Contribute to Male Germline-Specific Functions in Humans. PMID:28985295
Identification of a novel synaptic protein, TMTC3, involved in periventricular nodular heterotopia with intellectual disability and epilepsy. PMID:28973161
Fitness differences due to allelic variation at Esterase-4 locus in Drosophila ananassae. PMID:28947710
Insights into DDT Resistance from the Drosophila melanogaster Genetic Reference Panel. PMID:28935691
Death by over-eating: The Gaucher disease associated gene GBA1, identified in a screen for mediators of autophagic cell death, is necessary for developmental cell death in Drosophila midgut. PMID:28933588
An ant-plant mutualism through the lens of cGMP-dependent kinase genes. PMID:28904134
Drosophila melanogaster: Deciphering Alzheimer's Disease. PMID:28894399
Endocrine and physiological regulation of neutral fat storage in Drosophila. PMID:28893568
Machine Learning Analysis Identifies Drosophila Grunge/Atrophin as an Important Learning and Memory Gene Required for Memory Retention and Social Learning. PMID:28889104
Position Matters: Network Centrality Considerably Impacts Rates of Protein Evolution in the Human Protein-Protein Interaction Network. PMID:28854629
Relating past and present diet to phenotypic and transcriptomic variation in the fruit fly. PMID:28830340
The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants. PMID:28802044
Comparison of alternative approaches for analysing multi-level RNA-seq data. PMID:28792517
Genome-wide identification of Grainy head targets in Drosophila reveals regulatory interactions with the POU domain transcription factor Vvl. PMID:28760809
Naturally Segregating Variation at Ugt86Dd Contributes to Nicotine Resistance in Drosophila melanogaster. PMID:28743761
SIK3-HDAC4 signaling regulates Drosophila circadian male sex drive rhythm via modulating the DN1 clock neurons. PMID:28743754
Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins. PMID:28742022
Cis- and Trans-regulatory Effects on Gene Expression in a Natural Population of Drosophila melanogaster. PMID:28615283
Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons. PMID:28606304
Blocking promiscuous activation at cryptic promoters directs cell type-specific gene expression. PMID:28522526
Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults. PMID:28521739
A Drosophila model for developmental nicotine exposure. PMID:28498868
Intrinsic protein disorder reduces small-scale gene duplicability. PMID:28430886
Genomic responses to the socio-sexual environment in male Drosophila melanogaster exposed to conspecific rivals. PMID:28428330
Clustering of Drosophila housekeeping promoters facilitates their expression. PMID:28420691
TmCactin plays an important role in Gram-negative and -positive bacterial infection by regulating expression of 7 AMP genes in Tenebrio molitor. PMID:28418029
The developmental proteome of Drosophila melanogaster. PMID:28381612
in vivo localization of the neuronal ceroid lipofuscinosis proteins, CLN3 and CLN7, at endogenous expression levels. PMID:28365214
A fat-derived metabolite regulates a peptidergic feeding circuit in Drosophila. PMID:28350856
The toxicity of angiotensin converting enzyme inhibitors to larvae of the disease vectors Aedes aegypti and Anopheles gambiae. PMID:28345667
Testis-specific ATP synthase peripheral stalk subunits required for tissue-specific mitochondrial morphogenesis in Drosophila. PMID:28335714
SlgA, encoded by the homolog of the human schizophrenia-associated gene PRODH, acts in clock neurons to regulate Drosophila aggression. PMID:28331058
Evaluation of reference genes at different developmental stages for quantitative real-time PCR in Aedes aegypti. PMID:28300076
X-linkage is not a general inhibitor of tissue-specific gene expression in Drosophila melanogaster. PMID:28295031
Regions of very low H3K27me3 partition the Drosophila genome into topological domains. PMID:28282436
Identification of multiple functional receptors for tyramine on an insect secretory epithelium. PMID:28279025
Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan. PMID:28273481
A Mesh-Duox pathway regulates homeostasis in the insect gut. PMID:28248301
tBRD-1 and tBRD-2 regulate expression of genes necessary for spermatid differentiation. PMID:28235844
Decay of Sexual Trait Genes in an Asexual Parasitoid Wasp. PMID:28172869
Transition Zone Migration: A Mechanism for Cytoplasmic Ciliogenesis and Postaxonemal Centriole Elongation. PMID:28108487
The Goddard and Saturn Genes Are Essential for Drosophila Male Fertility and May Have Arisen De Novo. PMID:28104747
A homozygous FITM2 mutation causes a deafness-dystonia syndrome with motor regression and signs of ichthyosis and sensory neuropathy. PMID:28067622
TRAP-seq Profiling and RNAi-Based Genetic Screens Identify Conserved Glial Genes Required for Adult Drosophila Behavior. PMID:28066175
The Drosophila Accessory Gland as a Model for Prostate Cancer and Other Pathologies. PMID:28057306
Pleiotropic Effects of Loss of the Dα1 Subunit in Drosophila melanogaster: Implications for Insecticide Resistance. PMID:28049707
Evolution of Chemosensory Gene Families in Arthropods: Insight from the First Inclusive Comparative Transcriptome Analysis across Spider Appendages. PMID:28028122
Feeding-Related Traits Are Affected by Dosage of the foraging Gene in Drosophila melanogaster. PMID:28007892
Genomic Trajectories to Desiccation Resistance: Convergence and Divergence Among Replicate Selected Drosophila Lines. PMID:28007884
Transcriptome Analysis of Drosophila melanogaster Third Instar Larval Ring Glands Points to Novel Functions and Uncovers a Cytochrome p450 Required for Development. PMID:27974438
Neural Circuits Underlying Fly Larval Locomotion. PMID:27928962
An evolutionary conserved interaction between the Gcm transcription factor and the SF1 nuclear receptor in the female reproductive system. PMID:27886257
Systemic corazonin signalling modulates stress responses and metabolism in Drosophila. PMID:27810969
An RNAi Screen To Identify Protein Phosphatases That Function Within the Drosophila Circadian Clock. PMID:27784754
Reproductive activity triggers accelerated male mortality and decreases lifespan: genetic and gene expression determinants in Drosophila. PMID:27731328
Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila. PMID:27729457
Regulation of Dense-Core Granule Replenishment by Autocrine BMP Signalling in Drosophila Secondary Cells. PMID:27727275
Allatostatin A Signalling in Drosophila Regulates Feeding and Sleep and Is Modulated by PDF. PMID:27689358
Transcriptional Interference Promotes Rapid Expression Divergence of Drosophila Nested Genes. PMID:27664180
Selection on Position of Nonsense Codons in Introns. PMID:27630196
Drosophila Neprilysins Are Involved in Middle-Term and Long-Term Memory. PMID:27629706
c-Fos Repression by Piwi Regulates Drosophila Ovarian Germline Formation and Tissue Morphogenesis. PMID:27622269
Gene expression clines reveal local adaptation and associated trade-offs at a continental scale. PMID:27599812
Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster. PMID:27599372
An Eye on Trafficking Genes: Identification of Four Eye Color Mutations in Drosophila. PMID:27558665
Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. PMID:27558644
Testis-Specific Bb8 Is Essential in the Development of Spermatid Mitochondria. PMID:27529784
Odd-paired controls frequency doubling in Drosophila segmentation by altering the pair-rule gene regulatory network. PMID:27525481
Increased Glucose Transport into Neurons Rescues Aβ Toxicity in Drosophila. PMID:27524482
Weak Polygenic Selection Drives the Rapid Adaptation of the Chemosensory System: Lessons from the Upstream Regions of the Major Gene Families. PMID:27503297
The translation factors of Drosophila melanogaster. PMID:27494710
Achiasmy: Male Fruit Flies Are Not Ready to Mix. PMID:27486580
Sex-biased gene expression and sequence conservation in Atlantic and Pacific salmon lice (Lepeophtheirus salmonis). PMID:27377915
Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. PMID:27357258
Genomic and Transcriptomic Associations Identify a New Insecticide Resistance Phenotype for the Selective Sweep at the Cyp6g1 Locus of Drosophila melanogaster. PMID:27317781
The Drosophila ETV5 Homologue Ets96B: Molecular Link between Obesity and Bipolar Disorder. PMID:27280443
Similarities between decapod and insect neuropeptidomes. PMID:27257538
Molecular mechanism and functional significance of acid generation in the Drosophila midgut. PMID:27250760
Neurons That Underlie Drosophila melanogaster Reproductive Behaviors: Detection of a Large Male-Bias in Gene Expression in fruitless-Expressing Neurons. PMID:27247289
Bursicon-α subunit modulates dLGR2 activity in the adult Drosophila melanogaster midgut independently to Bursicon-β. PMID:27191973
A feedback amplification loop between stem cells and their progeny promotes tissue regeneration and tumorigenesis. PMID:27187149
The Drosophila melanogaster Muc68E Mucin Gene Influences Adult Size, Starvation Tolerance, and Cold Recovery. PMID:27172221
Evolution, Expression, and Function of Nonneuronal Ligand-Gated Chloride Channels in Drosophila melanogaster. PMID:27172217
Partial Functional Diversification of Drosophila melanogaster Septin Genes Sep2 and Sep5. PMID:27172205
The Drosophila prage Gene, Required for Maternal Transcript Destabilization in Embryos, Encodes a Predicted RNA Exonuclease. PMID:27172196
BOD1 Is Required for Cognitive Function in Humans and Drosophila. PMID:27166630
Seasonal phenotype-specific transcriptional reprogramming during metamorphosis in the European map butterfly Araschnia levana. PMID:27127610
Torso, a Drosophila receptor tyrosine kinase, plays a novel role in the larval fat body in regulating insulin signaling and body growth. PMID:27126913
An Indel Polymorphism in the MtnA 3' Untranslated Region Is Associated with Gene Expression Variation and Local Adaptation in Drosophila melanogaster. PMID:27120580
Positive Selection and Centrality in the Yeast and Fly Protein-Protein Interaction Networks. PMID:27119079
Two temporal functions of Glass: Ommatidium patterning and photoreceptor differentiation. PMID:27105580
Rapid evolution of the intersexual genetic correlation for fitness in Drosophila melanogaster. PMID:27077679
The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules. PMID:27072072
Dosage Compensation and the Distribution of Sex-Biased Gene Expression in Drosophila: Considerations and Genomic Constraints. PMID:27059220
The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replication. PMID:27053724
Learning defects in Drosophila growth restricted chico mutants are caused by attenuated adenylyl cyclase activity. PMID:27048332
Heterochromatin and genetic conflict. PMID:27035999
The Genetic Architecture of Natural Variation in Recombination Rate in Drosophila melanogaster. PMID:27035832
Drosophila polytene chromosome bands formed by gene introns. PMID:27025489
Glucocerebrosidase Deficiency in Drosophila Results in α-Synuclein-Independent Protein Aggregation and Neurodegeneration. PMID:27019408
Inducible DamID systems for genomic mapping of chromatin proteins in Drosophila. PMID:27001518
Spermatogenesis Drives Rapid Gene Creation and Masculinization of the X Chromosome in Stalk-Eyed Flies (Diopsidae). PMID:26951781
Disruption of POGZ Is Associated with Intellectual Disability and Autism Spectrum Disorders. PMID:26942287
Drosophila tools and assays for the study of human diseases. PMID:26935102
Ingestion of genetically modified yeast symbiont reduces fitness of an insect pest via RNA interference. PMID:26931800
The corticotropin-releasing factor-like diuretic hormone 44 (DH44) and kinin neuropeptides modulate desiccation and starvation tolerance in Drosophila melanogaster. PMID:26896569
Drosophila Nnf1 paralogs are partially redundant for somatic and germ line kinetochore function. PMID:26892014
Sex-specific regulation of Lgr3 in Drosophila neurons. PMID:26884206
Conservation, Duplication, and Divergence of Five Opsin Genes in Insect Evolution. PMID:26865071
The short-lived African turquoise killifish: an emerging experimental model for ageing. PMID:26839399
CoA protects against the deleterious effects of caloric overload in Drosophila. PMID:26805007
Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila. PMID:26787908
Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster. PMID:26758761
Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules. PMID:26748517
The Female Post-Mating Response Requires Genes Expressed in the Secondary Cells of the Male Accessory Gland in Drosophila melanogaster. PMID:26746709
A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae. PMID:26641531
Cloning and Functional Characterization of Two BTB Genes in the Predatory Mite Metaseiulus occidentalis. PMID:26640898
Early-onset sleep defects in Drosophila models of Huntington's disease reflect alterations of PKA/CREB signaling. PMID:26604145
Classification of Parkinson's Disease Genotypes in Drosophila Using Spatiotemporal Profiling of Vision. PMID:26597171
Proteome analysis of male accessory gland secretions in oriental fruit flies reveals juvenile hormone-binding protein, suggesting impact on female reproduction. PMID:26582577
A magnetic protein biocompass. PMID:26569474
BAR-SH3 sorting nexins are conserved interacting proteins of Nervous wreck that organize synapses and promote neurotransmission. PMID:26567222
Genetics on the Fly: A Primer on the Drosophila Model System. PMID:26564900
Heterochromatin remodeling by CDK12 contributes to learning in Drosophila. PMID:26508632
General Stress Responses in the Honey Bee. PMID:26466739
Cell type-specific translational repression of Cyclin B during meiosis in males. PMID:26443637
Genome-Wide Detection and Analysis of Multifunctional Genes. PMID:26436655
Getting Down to Specifics: Profiling Gene Expression and Protein-DNA Interactions in a Cell Type-Specific Manner. PMID:26410031
Muscarinic ACh Receptors Contribute to Aversive Olfactory Learning in Drosophila. PMID:26380118
Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. PMID:26370122
Flexible origin of hydrocarbon/pheromone precursors in Drosophila melanogaster. PMID:26353752
Transport proteins NHA1 and NHA2 are essential for survival, but have distinct transport modalities. PMID:26324901
Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes. PMID:26301956
β carbonic anhydrase is required for female fertility in Drosophila melanogaster. PMID:26300950
Evolutionary History of the Smyd Gene Family in Metazoans: A Framework to Identify the Orthologs of Human Smyd Genes in Drosophila and Other Animal Species. PMID:26230726
The Obesity-Linked Gene Nudt3 Drosophila Homolog Aps Is Associated With Insulin Signaling. PMID:26168034
The ecdysone receptor coactivator Taiman links Yorkie to transcriptional control of germline stem cell factors in somatic tissue. PMID:26143992
Unravelling the Evolution of the Allatostatin-Type A, KISS and Galanin Peptide-Receptor Gene Families in Bilaterians: Insights from Anopheles Mosquitoes. PMID:26135459
The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity. PMID:26119340
Variation in the X:Autosome Distribution of Male-Biased Genes among Drosophila melanogaster Tissues and Its Relationship with Dosage Compensation. PMID:26108491
Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. PMID:26095360
A novel role of Drosophila cytochrome P450-4e3 in permethrin insecticide tolerance. PMID:26073628
The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of Drosophila melanogaster. PMID:26020940
ADHD-associated dopamine transporter, latrophilin and neurofibromin share a dopamine-related locomotor signature in Drosophila. PMID:25962619
Parallel Gene Expression Differences between Low and High Latitude Populations of Drosophila melanogaster and D. simulans. PMID:25950438
Niche signaling promotes stem cell survival in the Drosophila testis via the JAK-STAT target DIAP1. PMID:25941003
Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active site. PMID:25905034
Linking gene expression to phenotypes via pathway information. PMID:25901272
Tracing the evolutionary origins of insect renal function. PMID:25896425
Implication of coronin 7 in body weight regulation in humans, mice and flies. PMID:25887538
As the fat flies: The dynamic lipid droplets of Drosophila embryos. PMID:25882628
Positive Selection at the Polyhomeotic Locus Led to Decreased Thermosensitivity of Gene Expression in Temperate Drosophila melanogaster. PMID:25855066
Systematic imaging reveals features and changing localization of mRNAs in Drosophila development. PMID:25838129
The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy. PMID:25836674
The small G protein Arl5 contributes to endosome-to-Golgi traffic by aiding the recruitment of the GARP complex to the Golgi. PMID:25795912
Parallel faster-X evolution of gene expression and protein sequences in Drosophila: beyond differences in expression properties and protein interactions. PMID:25789611
A single and rapid calcium wave at egg activation in Drosophila. PMID:25750438
Induction of excessive endoplasmic reticulum stress in the Drosophila male accessory gland results in infertility. PMID:25742606
X-to-autosome expression and msl-2 transcript abundance correlate among Drosophila melanogaster somatic tissues. PMID:25737812
Insect capa neuropeptides impact desiccation and cold tolerance. PMID:25730885
Multicopper oxidase-1 orthologs from diverse insect species have ascorbate oxidase activity. PMID:25701385
Fatty acid synthase cooperates with glyoxalase 1 to protect against sugar toxicity. PMID:25692475
Sex-specific trans-regulatory variation on the Drosophila melanogaster X chromosome. PMID:25679222
Constraints on the evolution of a doublesex target gene arising from doublesex's pleiotropic deployment. PMID:25675536
Generation of enteroendocrine cell diversity in midgut stem cell lineages. PMID:25670792
Comparison of larval and adult Drosophila astrocytes reveals stage-specific gene expression profiles. PMID:25653313
Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes. PMID:25652540
Microarray enriched gene rank. PMID:25649242
The putative Na⁺/Cl⁻-dependent neurotransmitter/osmolyte transporter inebriated in the Drosophila hindgut is essential for the maintenance of systemic water homeostasis. PMID:25613130
Adaptive regulation of testis gene expression and control of male fertility by the Drosophila hairpin RNA pathway. [Corrected]. PMID:25544562
Genome-wide analysis of drosophila circular RNAs reveals their structural and sequence properties and age-dependent neural accumulation. PMID:25544350
Mutations in KATNB1 cause complex cerebral malformations by disrupting asymmetrically dividing neural progenitors. PMID:25521378
Modulation of innate and learned sexual behaviors by the TRP channel Painless expressed in the fruit fly brain: behavioral genetic analysis and its implications. PMID:25520634
Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation. PMID:25517091
Exposure to endosulfan influences sperm competition in Drosophila melanogaster. PMID:25503806
Evolutionary diversification of insect innexins. PMID:25502029
The effect of neurospecific knockdown of candidate genes for locomotor behavior and sound production in Drosophila melanogaster. PMID:25494872
The contribution of the genomes of a termite and a locust to our understanding of insect neuropeptides and neurohormones. PMID:25477824
Genome-wide screen for modifiers of Na (+) /K (+) ATPase alleles identifies critical genetic loci. PMID:25476251
Control of metabolic adaptation to fasting by dILP6-induced insulin signaling in Drosophila oenocytes. PMID:25472843
A migrating ciliary gate compartmentalizes the site of axoneme assembly in Drosophila spermatids. PMID:25447994
The Drosophila surface glia transcriptome: evolutionary conserved blood-brain barrier processes. PMID:25426014
RACK1 controls IRES-mediated translation of viruses. PMID:25416947
Female responses to experimental removal of sexual selection components in Drosophila melanogaster. PMID:25406540
Current advances in systems and integrative biology. PMID:25379142
Sex-biased gene expression and sexual conflict throughout development. PMID:25376837
Expression profile and gene age jointly shaped the genome-wide distribution of premature termination codons in a Drosophila melanogaster population. PMID:25371429
Carrier of Wingless (Cow), a secreted heparan sulfate proteoglycan, promotes extracellular transport of Wingless. PMID:25360738
Mating system variation drives rapid evolution of the female transcriptome in Drosophila pseudoobscura. PMID:25360260
A conserved role for p48 homologs in protecting dopaminergic neurons from oxidative stress. PMID:25340742
Cloning and expression analysis of Drosophila extracellular Cu Zn superoxide dismutase. PMID:25339624
Overexpression of glutathione transferase E7 in Drosophila differentially impacts toxicity of organic isothiocyanates in males and females. PMID:25329882
Targeted inactivation of the rickets receptor in muscle compromises Drosophila viability. PMID:25278473
Two protein N-acetylgalactosaminyl transferases regulate synaptic plasticity by activity-dependent regulation of integrin signaling. PMID:25253852
Drosophila C virus systemic infection leads to intestinal obstruction. PMID:25253354
tBRD-1 selectively controls gene activity in the Drosophila testis and interacts with two new members of the bromodomain and extra-terminal (BET) family. PMID:25251222
Mef2 interacts with the Notch pathway during adult muscle development in Drosophila melanogaster. PMID:25247309
Population- and sex-biased gene expression in the excretion organs of Drosophila melanogaster. PMID:25246242
MicroRNAs influence reproductive responses by females to male sex peptide in Drosophila melanogaster. PMID:25245794
Transcription factor networks in Drosophila melanogaster. PMID:25242320
Chloride channels in stellate cells are essential for uniquely high secretion rates in neuropeptide-stimulated Drosophila diuresis. PMID:25228763
Transvection-based gene regulation in Drosophila is a complex and plastic trait. PMID:25213691
Loss of Na(+)/K(+)-ATPase in Drosophila photoreceptors leads to blindness and age-dependent neurodegeneration. PMID:25205229
Whole-genome expression analysis in the third instar larval midgut of Drosophila melanogaster. PMID:25193493
Comparative genomics and transcriptomics in ants provide new insights into the evolution and function of odorant binding and chemosensory proteins. PMID:25159315
BMP-regulated exosomes from Drosophila male reproductive glands reprogram female behavior. PMID:25154396
Indispensable pre-mitotic endocycles promote aneuploidy in the Drosophila rectum. PMID:25142462
Bmovo-1 regulates ovary size in the silkworm, Bombyx mori. PMID:25119438
No evidence for a global male-specific lethal complex-mediated dosage compensation contribution to the demasculinization of the Drosophila melanogaster X chromosome. PMID:25093841
Hypotonicity stimulates potassium flux through the WNK-SPAK/OSR1 kinase cascade and the Ncc69 sodium-potassium-2-chloride cotransporter in the Drosophila renal tubule. PMID:25086033
Cloning and characterization of a novel Drosophila stress induced DNase. PMID:25083901
Galactokinase is a novel modifier of calcineurin-induced cardiomyopathy in Drosophila. PMID:25081566
Genetic organization of interphase chromosome bands and interbands in Drosophila melanogaster. PMID:25072930
Discovering non-coding RNA elements in Drosophila 3' untranslated regions. PMID:24989864
Sex- and tissue-specific profiles of chemosensory gene expression in a herbivorous gall-inducing fly (Diptera: Cecidomyiidae). PMID:24948464
Integrating the interactome and the transcriptome of Drosophila. PMID:24913703
Contrasting influences of Drosophila white/mini-white on ethanol sensitivity in two different behavioral assays. PMID:24890118
Diacylglycerol lipase regulates lifespan and oxidative stress response by inversely modulating TOR signaling in Drosophila and C. elegans. PMID:24889782
Mito-nuclear interactions as drivers of gene movement on and off the X-chromosome. PMID:24885291
Relocation facilitates the acquisition of short cis-regulatory regions that drive the expression of retrogenes during spermatogenesis in Drosophila. PMID:24855141
First steps towards underdominant genetic transformation of insect populations. PMID:24844466
G×G×E for lifespan in Drosophila: mitochondrial, nuclear, and dietary interactions that modify longevity. PMID:24832080
Local control of intestinal stem cell homeostasis by enteroendocrine cells in the adult Drosophila midgut. PMID:24814146
Predicting performance and plasticity in the development of respiratory structures and metabolic systems. PMID:24812329
Rabconnectin-3a regulates vesicle endocytosis and canonical Wnt signaling in zebrafish neural crest migration. PMID:24802872
Altering the sex determination pathway in Drosophila fat body modifies sex-specific stress responses. PMID:24789992
An NAD(+) biosynthetic pathway enzyme functions cell non-autonomously in C. elegans development. PMID:24753121
Drosophila microbiota modulates host metabolic gene expression via IMD/NF-κB signaling. PMID:24733183
Apocrine secretion in Drosophila salivary glands: subcellular origin, dynamics, and identification of secretory proteins. PMID:24732043
Tools for gene-regulatory analyses in the marine annelid Platynereis dumerilii. PMID:24714200
The RNA-binding protein Rumpelstiltskin antagonizes gypsy chromatin insulator function in a tissue-specific manner. PMID:24706949
Unique and shared functions of nuclear lamina LEM domain proteins in Drosophila. PMID:24700158
Retrograde neurotrophin signaling through Tollo regulates synaptic growth in Drosophila. PMID:24662564
Resources for functional genomics studies in Drosophila melanogaster. PMID:24653003
A neuron-glia interaction involving GABA transaminase contributes to sleep loss in sleepless mutants. PMID:24637426
Dedifferentiation of neurons precedes tumor formation in Lola mutants. PMID:24631403
Latent luciferase activity in the fruit fly revealed by a synthetic luciferin. PMID:24616520
High intake of dietary sugar enhances bisphenol A (BPA) disruption and reveals ribosome-mediated pathways of toxicity. PMID:24614930
The Arf family G protein Arl1 is required for secretory granule biogenesis in Drosophila. PMID:24610947
Insight into insulin secretion from transcriptome and genetic analysis of insulin-producing cells of Drosophila. PMID:24558258
The ontogeny and evolution of sex-biased gene expression in Drosophila melanogaster. PMID:24526011
Oxidative stress is not a major contributor to somatic mitochondrial DNA mutations. PMID:24516391
A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages. PMID:24510058
Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11. PMID:24492843
The heterodimeric glycoprotein hormone, GPA2/GPB5, regulates ion transport across the hindgut of the adult mosquito, Aedes aegypti. PMID:24466069
A comparison of midline and tracheal gene regulation during Drosophila development. PMID:24465586
Origin and spread of de novo genes in Drosophila melanogaster populations. PMID:24457212
Evolutionary rate covariation identifies new members of a protein network required for Drosophila melanogaster female post-mating responses. PMID:24453993
Male-specific fruitless isoforms target neurodevelopmental genes to specify a sexually dimorphic nervous system. PMID:24440396
Faster evolving Drosophila paralogs lose expression rate and ubiquity and accumulate more non-synonymous SNPs. PMID:24438455
A long-term demasculinization of X-linked intergenic noncoding RNAs in Drosophila melanogaster. PMID:24407956
Neprilysins: an evolutionarily conserved family of metalloproteases that play important roles in reproduction in Drosophila. PMID:24395329
An allele of sequoia dominantly enhances a trio mutant phenotype to influence Drosophila larval behavior. PMID:24376789
The Drosophila neuropeptides PDF and sNPF have opposing electrophysiological and molecular effects on central neurons. PMID:24353297
A global in vivo Drosophila RNAi screen identifies a key role of ceramide phosphoethanolamine for glial ensheathment of axons. PMID:24348263
Translational profiling of clock cells reveals circadianly synchronized protein synthesis. PMID:24348200
Extensive use of RNA-binding proteins in Drosophila sensory neuron dendrite morphogenesis. PMID:24347626
Identification of sphingolipid metabolites that induce obesity via misregulation of appetite, caloric intake and fat storage in Drosophila. PMID:24339790
Genome-wide gene expression effects of sex chromosome imprinting in Drosophila. PMID:24318925
Isolation and functional characterization of calcitonin-like diuretic hormone receptors in Rhodnius prolixus. PMID:24312424
Developmental variation of the SUUR protein binding correlates with gene regulation and specific chromatin types in D. melanogaster. PMID:24292500
Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin. PMID:24281155
Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin. PMID:24281154
Expression-based segmentation of the Drosophila genome. PMID:24256206
The Drosophila early ovarian transcriptome provides insight to the molecular causes of recombination rate variation across genomes. PMID:24228734
Two rapidly evolving genes contribute to male fitness in Drosophila. PMID:24221639
Adaptive divergence of a transcriptional enhancer between populations of Drosophila melanogaster. PMID:24218636
A glutamate-dependent redox system in blood cells is integral for phagocytosis in Drosophila melanogaster. PMID:24210616
Mapping an atlas of tissue-specific Drosophila melanogaster metabolomes by high resolution mass spectrometry. PMID:24205093
Subdued, a TMEM16 family Ca²⁺-activated Cl⁻channel in Drosophila melanogaster with an unexpected role in host defense. PMID:24192034
Uncovering the functional constraints underlying the genomic organization of the odorant-binding protein genes. PMID:24148943
De novo ORFs in Drosophila are important to organismal fitness and evolved rapidly from previously non-coding sequences. PMID:24146629
Genome-wide and cell-specific epigenetic analysis challenges the role of polycomb in Drosophila spermatogenesis. PMID:24146626
Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila. PMID:24142897
Proteomic-based insight into Malpighian tubules of silkworm Bombyx mori. PMID:24098719
CAST-ChIP maps cell-type-specific chromatin states in the Drosophila central nervous system. PMID:24095734
The evolution and functional significance of nested gene structures in Drosophila melanogaster. PMID:24084778
MEF2 is an in vivo immune-metabolic switch. PMID:24075010
Maternal depletion of Piwi, a component of the RNAi system, impacts heterochromatin formation in Drosophila. PMID:24068954
Factors that regulate insulin producing cells and their output in Drosophila. PMID:24062693
Gudu, an Armadillo repeat-containing protein, is required for spermatogenesis in Drosophila. PMID:24055424
The roles of cis- and trans-regulation in the evolution of regulatory incompatibilities and sexually dimorphic gene expression. PMID:24043293
Towards the elements of successful insect RNAi. PMID:24041495
'Escaping' the X chromosome leads to increased gene expression in the male germline of Drosophila melanogaster. PMID:24022496
The Oct1 homolog Nubbin is a repressor of NF-κB-dependent immune gene expression that increases the tolerance to gut microbiota. PMID:24010524
GRASP [Genomic Resource Access for Stoichioproteomics]: comparative explorations of the atomic content of 12 Drosophila proteomes. PMID:24007337
Physiological and stem cell compartmentalization within the Drosophila midgut. PMID:23991285
Natalisin, a tachykinin-like signaling system, regulates sexual activity and fecundity in insects. PMID:23980168
Functional genomic analyses of two morphologically distinct classes of Drosophila sensory neurons: post-mitotic roles of transcription factors in dendritic patterning. PMID:23977298
Development of RNAi methods for Peregrinus maidis, the corn planthopper. PMID:23950915
Functional analysis of PGRP-LA in Drosophila immunity. PMID:23922788
Data-mining the FlyAtlas online resource to identify core functional motifs across transporting epithelia. PMID:23895496
The insulator protein Suppressor of Hairy-wing is an essential transcriptional repressor in the Drosophila ovary. PMID:23884443
Evolution of three parent genes and their retrogene copies in Drosophila species. PMID:23841016
Genome-Wide Responses of Female Fruit Flies Subjected to Divergent Mating Regimes. PMID:23826372
Effete, a Drosophila chromatin-associated ubiquitin-conjugating enzyme that affects telomeric and heterochromatic position effect variegation. PMID:23821599
Modeling the genetic basis for human sleep disorders in Drosophila. PMID:23802043
Two sexes, one genome: the evolutionary dynamics of intralocus sexual conflict. PMID:23789088
RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes. PMID:23778934
Combining genome-wide methods to investigate the genetic complexity of courtship song variation in Drosophila melanogaster. PMID:23777628
Transcriptional response of honey bee larvae infected with the bacterial pathogen Paenibacillus larvae. PMID:23762370
The RNA export factor, Nxt1, is required for tissue specific transcriptional regulation. PMID:23754955
Microhomology-mediated intron loss during metazoan evolution. PMID:23737326
Receptor tyrosine kinases in Drosophila development. PMID:23732470
Distinct mechanisms of transcriptional pausing orchestrated by GAGA factor and M1BP, a novel transcription factor. PMID:23708796
Females and males contribute in opposite ways to the evolution of gene order in Drosophila. PMID:23696898
Fermitins, the orthologs of mammalian Kindlins, regulate the development of a functional cardiac syncytium in Drosophila melanogaster. PMID:23690969
Diet controls Drosophila follicle stem cell proliferation via Hedgehog sequestration and release. PMID:23690177
The genetic makeup of the Drosophila piRNA pathway. PMID:23665231
A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila. PMID:23665228
The impact of trans-regulation on the evolutionary rates of metazoan proteins. PMID:23658220
Metabolomic profiling reveals that Drosophila melanogaster larvae with the y mutation have altered lysine metabolism. PMID:23650603
Chromatin-associated proteins HP1 and Mod(mdg4) modify Y-linked regulatory variation in the drosophila testis. PMID:23636736
Genome-wide association study of sleep in Drosophila melanogaster. PMID:23617951
dRYBP contributes to the negative regulation of the Drosophila Imd pathway. PMID:23596533
Natural variation of the Y chromosome suppresses sex ratio distortion and modulates testis-specific gene expression in Drosophila simulans. PMID:23591516
The Smc5/Smc6/MAGE complex confers resistance to caffeine and genotoxic stress in Drosophila melanogaster. PMID:23555814
Molecular basis of the dopaminergic system in the cricket Gryllus bimaculatus. PMID:23539475
The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage. PMID:23525007
Polycomb silencing of the Drosophila 4E-BP gene regulates imaginal disc cell growth. PMID:23523430
Genetic determinants of phosphate response in Drosophila. PMID:23520455
Enhancer trap infidelity in Drosophila optomotor-blind. PMID:23519069
Drosophila melanogaster as an emerging translational model of human nephrolithiasis. PMID:23500641
HP1a, Su(var)3-9, SETDB1 and POF stimulate or repress gene expression depending on genomic position, gene length and expression pattern in Drosophila melanogaster. PMID:23476027
The BEN domain is a novel sequence-specific DNA-binding domain conserved in neural transcriptional repressors. PMID:23468431
Patterning and regulatory associations of DNA methylation are mirrored by histone modifications in insects. PMID:23458712
The genetic architecture of degenerin/epithelial sodium channels in Drosophila. PMID:23449991
Shaping up for action: the path to physiological maturation in the renal tubules of Drosophila. PMID:23445869
Inhibition of diuretic stimulation of an insect secretory epithelium by a cGMP-dependent protein kinase. PMID:23445619
Why does a protein's evolutionary rate vary over time? PMID:23436005
Coordinate regulation of eIF2α phosphorylation by PPP1R15 and GCN2 is required during Drosophila development. PMID:23418347
Nucleolar stress in Drosophila melanogaster: RNAi-mediated depletion of Nopp140. PMID:23412656
Evolutionary history of eukaryotic α-glucosidases from the α-amylase family. PMID:23397242
Optimising homing endonuclease gene drive performance in a semi-refractory species: the Drosophila melanogaster experience. PMID:23349805
Mutation of a NCKX eliminates glial microdomain calcium oscillations and enhances seizure susceptibility. PMID:23325253
Protein correlation profiles identify lipid droplet proteins with high confidence. PMID:23319140
Common variants of Drosophila melanogaster Cyp6d2 cause camptothecin sensitivity and synergize with loss of Brca2. PMID:23316441
Isolation of the bioactive peptides CCHamide-1 and CCHamide-2 from Drosophila and their putative role in appetite regulation as ligands for G protein-coupled receptors. PMID:23293632
The border between the ultrabithorax and abdominal-A regulatory domains in the Drosophila bithorax complex. PMID:23288934
Identification, genomic organization, and oxidative stress response of a sigma class glutathione S-transferase gene (AccGSTS1) in the honey bee, Apis cerana cerana. PMID:23250585
Cell-type-specific roles of Na+/K+ ATPase subunits in Drosophila auditory mechanosensation. PMID:23248276
Significance of the centrally expressed TRP channel painless in Drosophila courtship memory. PMID:23247253
Circadian regulation of glutathione levels and biosynthesis in Drosophila melanogaster. PMID:23226288
Role of histone deacetylases in gene regulation at nuclear lamina. PMID:23226217
More than two decades of research on insect neuropeptide GPCRs: an overview. PMID:23226142
Drosophila protein interaction map (DPiM): a paradigm for metazoan protein complex interactions. PMID:23222005
Calcium and egg activation in Drosophila. PMID:23218670
The bromodomain-containing protein tBRD-1 is specifically expressed in spermatocytes and is essential for male fertility. PMID:23213453
Receptor-type guanylyl cyclase Gyc76C is required for development of the Drosophila embryonic somatic muscle. PMID:23213443
Tissue-specific regulation of chromatin insulator function. PMID:23209434
Sex, stem cells and tumors in the Drosophila ovary. PMID:23208193
FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster. PMID:23203866
Genomic variation and its impact on gene expression in Drosophila melanogaster. PMID:23189034
Identification of gene expression changes associated with long-term memory of courtship rejection in Drosophila males. PMID:23173095
Population and sex differences in Drosophila melanogaster brain gene expression. PMID:23170910
Identification of genetic suppressors of the Sin3A knockdown wing phenotype. PMID:23166712
Population genomic analysis of base composition evolution in Drosophila melanogaster. PMID:23160062
A novel role for lipid droplets in the organismal antibacterial response. PMID:23150794
Molecular and pharmacological characterization of serotonin 5-HT2α and 5-HT7 receptors in the salivary glands of the blowfly Calliphora vicina. PMID:23145175
Effects of premature termination codon polymorphisms in the Drosophila pseudoobscura subclade. PMID:23132097
Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model. PMID:23118342
Large neurological component to genetic differences underlying biased sperm use in Drosophila. PMID:23105014
Drosophila sperm proteome evolution: Insights from comparative genomic approaches. PMID:23087838
Cloning and functional characterization of inward-rectifying potassium (Kir) channels from Malpighian tubules of the mosquito Aedes aegypti. PMID:23085358
Global analysis of target genes of 21 members of the ZAD transcription factor family in Drosophila melanogaster. PMID:23085320
Transcriptional profiles of mating-responsive genes from testes and male accessory glands of the Mediterranean fruit fly, Ceratitis capitata. PMID:23071645
Faster-X evolution of gene expression in Drosophila. PMID:23071459
Drosophila Ninjurin A induces nonapoptotic cell death. PMID:23028562
Genomics of sex determination in Drosophila. PMID:23023665
Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48. PMID:23023331
Induced transcription results in local changes in chromatin structure, replication timing, and DNA polytenization in a site of intercalary heterochromatin. PMID:23015267
In vivo Drosophilia genetic model for calcium oxalate nephrolithiasis. PMID:22993075
Transcription termination between polo and snap, two closely spaced tandem genes of D. melanogaster. PMID:22992452
Sex peptide of Drosophila melanogaster males is a global regulator of reproductive processes in females. PMID:22977156
Little evidence for demasculinization of the Drosophila X chromosome among genes expressed in the male germline. PMID:22975718
Gene expression in late-life. PMID:22973294
Insulin-Producing Cells in the Drosophila Brain also Express Satiety-Inducing Cholecystokinin-Like Peptide, Drosulfakinin. PMID:22969751
Drosophila melanogaster Acetyl-CoA-carboxylase sustains a fatty acid-dependent remote signal to waterproof the respiratory system. PMID:22956916
Segmental dataset and whole body expression data do not support the hypothesis that non-random movement is an intrinsic property of Drosophila retrogenes. PMID:22950647
A Question Never Comes Alone: Comments on 'What is Aging?'. PMID:22936946
Katanin p60-like1 promotes microtubule growth and terminal dendrite stability in the larval class IV sensory neurons of Drosophila. PMID:22915107
Microarray-based capture of novel expressed cell type-specific transfrags (CoNECT) to annotate tissue-specific transcription in Drosophila melanogaster. PMID:22908036
Mulet (mlt) encodes a tubulin-binding cofactor E-like homolog required for spermatid individualization in Drosophila melanogaster. PMID:22885996
Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. PMID:22884528
FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal. PMID:22884370
Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of Drosophila. PMID:22870402
Cell type-specific genomics of Drosophila neurons. PMID:22855560
Activating transcription factor 3 regulates immune and metabolic homeostasis. PMID:22851689
Multicopper oxidase-1 is a ferroxidase essential for iron homeostasis in Drosophila melanogaster. PMID:22847425
Identified peptidergic neurons in the Drosophila brain regulate insulin-producing cells, stress responses and metabolism by coexpressed short neuropeptide F and corazonin. PMID:22828865
High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy. PMID:22801366
A versatile method for cell-specific profiling of translated mRNAs in Drosophila. PMID:22792260
Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila. PMID:22791894
Gene duplication, tissue-specific gene expression and sexual conflict in stalk-eyed flies (Diopsidae). PMID:22777023
Evolution of gene expression and expression plasticity in long-term experimental populations of Drosophila melanogaster maintained under constant and variable ethanol stress. PMID:22774776
shutdown is a component of the Drosophila piRNA biogenesis machinery. PMID:22753781
Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6. PMID:22740637
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3. PMID:22728672
Re-analysis of the larval testis data on meiotic sex chromosome inactivation revealed evidence for tissue-specific gene expression related to the drosophila X chromosome. PMID:22691264
Type-I prenyl protease function is required in the male germline of Drosophila melanogaster. PMID:22690372
Global patterns of tissue-specific alternative polyadenylation in Drosophila. PMID:22685694
Divergent functions through alternative splicing: the Drosophila CRMP gene in pyrimidine metabolism, brain, and behavior. PMID:22649077
What model organisms and interactomics can reveal about the genetics of human obesity. PMID:22618246
Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes. PMID:22574197
A cytochrome p450 conserved in insects is involved in cuticle formation. PMID:22574182
Differential evolutionary wiring of the tyrosine kinase Btk. PMID:22574122
Crossveinless d is a vitellogenin-like lipoprotein that binds BMPs and HSPGs, and is required for normal BMP signaling in the Drosophila wing. PMID:22573617
Gut-associated microbes of Drosophila melanogaster. PMID:22572876
Thematic review series: Lipid droplet synthesis and metabolism: from yeast to man. Lipid droplet-based storage fat metabolism in Drosophila. PMID:22566574
Loss of the starvation-induced gene Rack1 leads to glycogen deficiency and impaired autophagic responses in Drosophila. PMID:22562043
The FGLamide-allatostatins influence foraging behavior in Drosophila melanogaster. PMID:22558326
Transcriptome profiling of the intoxication response of Tenebrio molitor larvae to Bacillus thuringiensis Cry3Aa protoxin. PMID:22558093
Reshaping of global gene expression networks and sex-biased gene expression by integration of a young gene. PMID:22543869
Mutations in NSUN2 cause autosomal-recessive intellectual disability. PMID:22541559
Disentangling the relationship between sex-biased gene expression and X-linkage. PMID:22499666
Functional correlates of positional and gender-specific renal asymmetry in Drosophila. PMID:22496733
Using translational enhancers to increase transgene expression in Drosophila. PMID:22493255
Phenotypic plasticity of the Drosophila transcriptome. PMID:22479193
Buffering and proteolysis are induced by segmental monosomy in Drosophila melanogaster. PMID:22434883
Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary. PMID:22406832
The apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers. PMID:22398720
Glypican Gene GPC5 Participates in the Behavioral Response to Ethanol: Evidence from Humans, Mice, and Fruit Flies. PMID:22384374
Conserved properties of Drosophila and human spermatozoal mRNA repertoires. PMID:22378807
Roles of major facilitator superfamily transporters in phosphate response in Drosophila. PMID:22359624
Evolutionary Genomics of Genes Involved in Olfactory Behavior in the Drosophila melanogaster Species Group. PMID:22346339
Rate of amino acid substitution is influenced by the degree and conservation of male-biased transcription over 50 myr of Drosophila evolution. PMID:22321769
Ion and solute transport by Prestin in Drosophila and Anopheles. PMID:22321763
Rhodopsin 5- and Rhodopsin 6-mediated clock synchronization in Drosophila melanogaster is independent of retinal phospholipase C-β signaling. PMID:22306971
Chromatin domain boundary element search tool for Drosophila. PMID:22287636
Mechanism and function of Drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor. PMID:22253819
The Drosophila melanogaster seminal fluid protease "seminase" regulates proteolytic and post-mating reproductive processes. PMID:22253601
Fine scale analysis of gene expression in Drosophila melanogaster gonads reveals Programmed cell death 4 promotes the differentiation of female germline stem cells. PMID:22252300
A novel approach for directing transgene expression in Drosophila: T2A-Gal4 in-frame fusion. PMID:22209908
insomniac and Cullin-3 regulate sleep and wakefulness in Drosophila. PMID:22196332
Genetic modulation of Rpd3 expression impairs long-term courtship memory in Drosophila. PMID:22195015
Functional genome annotation of Drosophila seminal fluid proteins using transcriptional genetic networks. PMID:22189604
Mechanisms of intron gain and loss in Drosophila. PMID:22182367
Hyperactive BMP signaling induced by ALK2(R206H) requires type II receptor function in a Drosophila model for classic fibrodysplasia ossificans progressiva. PMID:22174087
Subfunctionalization reduces the fitness cost of gene duplication in humans by buffering dosage imbalances. PMID:22168623
Birth, death, and replacement of karyopherins in Drosophila. PMID:22160828
Glial-derived prodegenerative signaling in the Drosophila neuromuscular system. PMID:22153373
Drosophila Dynein intermediate chain gene, Dic61B, is required for spermatogenesis. PMID:22145020
Identification of a TPX2-like microtubule-associated protein in Drosophila. PMID:22140519
Genome-wide analysis of retrogene polymorphisms in Drosophila melanogaster. PMID:22135405
A remarkably stable TipE gene cluster: evolution of insect Para sodium channel auxiliary subunits. PMID:22098672
Ephemeral association between gene CG5762 and hybrid male sterility in Drosophila sibling species. PMID:22052252
Widespread polymorphism in the positions of stop codons in Drosophila melanogaster. PMID:22051795
The MOF-containing NSL complex associates globally with housekeeping genes, but activates only a defined subset. PMID:22039099
A protein complex network of Drosophila melanogaster. PMID:22036573
The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster. PMID:22022283
EGFR signaling modulates synaptic connectivity via Gurken. PMID:22021126
De Novo assembly of the Manila clam Ruditapes philippinarum transcriptome provides new insights into expression bias, mitochondrial doubly uniparental inheritance and sex determination. PMID:21976711
The genomic response to courtship song stimulation in female Drosophila melanogaster. PMID:21976688
Interspecific Y chromosome introgressions disrupt testis-specific gene expression and male reproductive phenotypes in Drosophila. PMID:21969588
Temporally variable selection on proteolysis-related reproductive tract proteins in Drosophila. PMID:21940639
Genetic evidence for a protective role of the peritrophic matrix against intestinal bacterial infection in Drosophila melanogaster. PMID:21896728
Drosophila Inducer of MEiosis 4 (IME4) is required for Notch signaling during oogenesis. PMID:21873203
The plausible reason why the length of 5' untranslated region is unrelated to organismal complexity. PMID:21871111
A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. PMID:21863019
Sex chromosome-specific regulation in the Drosophila male germline but little evidence for chromosomal dosage compensation or meiotic inactivation. PMID:21857805
The fat body transcriptomes of the yellow fever mosquito Aedes aegypti, pre- and post- blood meal. PMID:21818341
Essential role of Duox in stabilization of Drosophila wing. PMID:21808060
Somatic sex-specific transcriptome differences in Drosophila revealed by whole transcriptome sequencing. PMID:21756339
Identification of a classical bipartite nuclear localization signal in the Drosophila TEA/ATTS protein scalloped. PMID:21731746
Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression. PMID:21724831
The genome of the leaf-cutting ant Acromyrmex echinatior suggests key adaptations to advanced social life and fungus farming. PMID:21719571
Associations between Variation in X Chromosome Male Reproductive Genes and Sperm Competitive Ability in Drosophila melanogaster. PMID:21716718
Cooperative and antagonistic contributions of two heterochromatin proteins to transcriptional regulation of the Drosophila sex determination decision. PMID:21695246
Immunolocalization of the short neuropeptide F receptor in queen brains and ovaries of the red imported fire ant (Solenopsis invicta Buren). PMID:21672256
RNA sequencing reveals two major classes of gene expression levels in metazoan cells. PMID:21654674
Dissecting gene expression in mosquito. PMID:21649884
A comprehensive gene expression atlas of sex- and tissue-specificity in the malaria vector, Anopheles gambiae. PMID:21649883
Drosophila eggshell production: identification of new genes and coordination by Pxt. PMID:21637834
Insulin production and signaling in renal tubules of Drosophila is under control of tachykinin-related peptide and regulates stress resistance. PMID:21572965
Wake-up-call, a lin-52 paralogue, and Always early, a lin-9 homologue physically interact, but have opposing functions in regulating testis-specific gene expression. PMID:21570388
Unique aspects of transcription regulation in male germ cells. PMID:21555408
A cautionary note for retrocopy identification: DNA-based duplication of intron-containing genes significantly contributes to the origination of single exon genes. PMID:21551137
Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. PMID:21549331
Lack of global meiotic sex chromosome inactivation, and paucity of tissue-specific gene expression on the Drosophila X chromosome. PMID:21542906
The nucleoporin Seh1 forms a complex with Mio and serves an essential tissue-specific function in Drosophila oogenesis. PMID:21521741
Transcriptomic analysis in a Drosophila model identifies previously implicated and novel pathways in the therapeutic mechanism in neuropsychiatric disorders. PMID:21503142
Females with a mutation in a nuclear-encoded mitochondrial protein pay a higher cost of survival than do males in Drosophila. PMID:21498433
Drosophila Ctf4 is essential for efficient DNA replication and normal cell cycle progression. PMID:21470422
Expansion and functional diversification of a leucyl aminopeptidase family that encodes the major protein constituents of Drosophila sperm. PMID:21466698
A link between impaired purine nucleotide synthesis and apoptosis in Drosophila melanogaster. PMID:21441212
The poly(A) polymerase GLD2 is required for spermatogenesis in Drosophila melanogaster. PMID:21427144
Towards a semen proteome of the dengue vector mosquito: protein identification and potential functions. PMID:21423647
Robust RT-qPCR data normalization: validation and selection of internal reference genes during post-experimental data analysis. PMID:21423626
Support for multiple classes of local expression clusters in Drosophila melanogaster, but no evidence for gene order conservation. PMID:21414197
Evolution of a tissue-specific splicing network. PMID:21406555
Female Drosophila melanogaster gene expression and mate choice: the X chromosome harbours candidate genes underlying sexual isolation. PMID:21386982
Rab3-GAP controls the progression of synaptic homeostasis at a late stage of vesicle release. PMID:21338884
Blanks, a nuclear siRNA/dsRNA-binding complex component, is required for Drosophila spermiogenesis. PMID:21300896
Neurotransmitter Transporter-Like: a male germline-specific SLC6 transporter required for Drosophila spermiogenesis. PMID:21298005
Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50. PMID:21289096
A database for the analysis of immunity genes in Drosophila: PADMA database. PMID:21273816
Towards a more nuanced understanding of the relationship between sex-biased gene expression and rates of protein-coding sequence evolution. PMID:21239389
Insulin signaling, lifespan and stress resistance are modulated by metabotropic GABA receptors on insulin producing cells in the brain of Drosophila. PMID:21209905
The transcriptional diversity of 25 Drosophila cell lines. PMID:21177962
Neighbourhood continuity is not required for correct testis gene expression in Drosophila. PMID:21151342
Gene expression divergence recapitulates the developmental hourglass model. PMID:21150996
CDase is a pan-ceramidase in Drosophila. PMID:21148295
Fine-scale genetic mapping of a hybrid sterility factor between Drosophila simulans and D. mauritiana: the varied and elusive functions of "speciation genes". PMID:21144061
2R and remodeling of vertebrate signal transduction engine. PMID:21144020
Evolutionary patterns of amino acid substitutions in 12 Drosophila genomes. PMID:21143793
Expression of ribosomal protein L22e family members in Drosophila melanogaster: rpL22-like is differentially expressed and alternatively spliced. PMID:21138957
Computational biology for ageing. PMID:21115530
The Drosophila NR4A nuclear receptor DHR38 regulates carbohydrate metabolism and glycogen storage. PMID:21084378
Analyses of nuclearly encoded mitochondrial genes suggest gene duplication as a mechanism for resolving intralocus sexually antagonistic conflict in Drosophila. PMID:21037198
Socially-responsive gene expression in male Drosophila melanogaster is influenced by the sex of the interacting partner. PMID:20980240
Transcellular and paracellular pathways of transepithelial fluid secretion in Malpighian (renal) tubules of the yellow fever mosquito Aedes aegypti. PMID:20946239
Intronic AT skew is a defendable proxy for germline transcription but does not predict crossing-over or protein evolution rates in Drosophila melanogaster. PMID:20938653
Mating alters gene expression patterns in Drosophila melanogaster male heads. PMID:20937114
Metallothionein and the biology of aging. PMID:20933613
Drosophila provides rapid modeling of renal development, function, and disease. PMID:20926630
Dynamic, mating-induced gene expression changes in female head and brain tissues of Drosophila melanogaster. PMID:20925960
Systematic protein location mapping reveals five principal chromatin types in Drosophila cells. PMID:20888037
Evolutionary analysis and expression profiling of zebra finch immune genes. PMID:20884724
Drosophila variable nurse cells encodes arrest defective 1 (ARD1), the catalytic subunit of the major N-terminal acetyltransferase complex. PMID:20882681
Sex linkage, sex-specific selection, and the role of recombination in the evolution of sexually dimorphic gene expression. PMID:20874735
Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster. PMID:20870963
Insect seminal fluid proteins: identification and function. PMID:20868282
The essential role of bursicon during Drosophila development. PMID:20807433
Age-dependent chromosomal distribution of male-biased genes in Drosophila. PMID:20798392
Drcd-1 related: a positively selected spermatogenesis retrogene in Drosophila. PMID:20694743
Characterization of the first beta-class carbonic anhydrase from an arthropod (Drosophila melanogaster) and phylogenetic analysis of beta-class carbonic anhydrases in invertebrates. PMID:20659325
Conservation of male-specific expression of novel phosphoprotein phosphatases in Drosophila. PMID:20632030
Metabolic stress responses in Drosophila are modulated by brain neurosecretory cells that produce multiple neuropeptides. PMID:20628603
Global analysis of trans-splicing in Drosophila. PMID:20615941
Gene density profile reveals the marking of late replicated domains in the Drosophila melanogaster genome. PMID:20602235
Fragile regions and not functional constraints predominate in shaping gene organization in the genus Drosophila. PMID:20601587
Iron testes: sperm mitochondria as a context for dissecting iron metabolism. PMID:20598113
Interaction between eye pigment genes and tau-induced neurodegeneration in Drosophila melanogaster. PMID:20592261
Drosophila mitoferrin is essential for male fertility: evidence for a role of mitochondrial iron metabolism during spermatogenesis. PMID:20565922
Functional characterization of the Frost gene in Drosophila melanogaster: importance for recovery from chill coma. PMID:20532197
The SILAC fly allows for accurate protein quantification in vivo. PMID:20525996
UDP-galactose 4' epimerase (GALE) is essential for development of Drosophila melanogaster. PMID:20519568
Paralogous genes involved in juvenile hormone action in Drosophila melanogaster. PMID:20498297
A novel predicted bromodomain-related protein affects coordination between meiosis and spermiogenesis in Drosophila and is required for male meiotic cytokinesis. PMID:20491580
Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster. PMID:20459830
Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq. PMID:20440302
Non-random genomic integration - an intrinsic property of retrogenes in Drosophila? PMID:20426838
Mutational bias shaping fly copy number variation: implications for genome evolution. PMID:20416969
Evolution and spermatogenesis. PMID:20403864
The developmental expression dynamics of Drosophila melanogaster transcription factors. PMID:20384991
The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children. PMID:20380707
Adaptive evolution of genes duplicated from the Drosophila pseudoobscura neo-X chromosome. PMID:20351054
Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. PMID:20333234
Widespread transcriptional autosomal dosage compensation in Drosophila correlates with gene expression level. PMID:20333221
A universal nonmonotonic relationship between gene compactness and expression levels in multicellular eukaryotes. PMID:20333206
A complex suite of forces drives gene traffic from Drosophila X chromosomes. PMID:20333188
MIPs are ancestral ligands for the sex peptide receptor. PMID:20308537
The sexually antagonistic genes of Drosophila melanogaster. PMID:20305719
Neuropeptidomics of the mosquito Aedes aegypti. PMID:20163154
Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy. PMID:20157574
It's all about balance: p53 and aging. PMID:20157572
dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila. PMID:20152183
The cytolinker Pigs is a direct target and a negative regulator of Notch signalling. PMID:20150280
Molecular social interactions: Drosophila melanogaster seminal fluid proteins as a case study. PMID:20109658
Convergently recruited nuclear transport retrogenes are male biased in expression and evolving under positive selection in Drosophila. PMID:20065068
Determination of gene expression patterns using in situ hybridization to Drosophila testes. PMID:20010932
Mislocalization of mitochondria and compromised renal function and oxidative stress resistance in Drosophila SesB mutants. PMID:20009008
The DHR96 nuclear receptor controls triacylglycerol homeostasis in Drosophila. PMID:19945405
Stage-specific expression profiling of Drosophila spermatogenesis suggests that meiotic sex chromosome inactivation drives genomic relocation of testis-expressed genes. PMID:19936020
FlyTED: the Drosophila Testis Gene Expression Database. PMID:19934263
Highly expressed and slowly evolving proteins share compositional properties with thermophilic proteins. PMID:19910385
Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain. PMID:19884312
Genetic effects in Drosophila on the potency of diverse general anesthetics: a distinctive pattern of altered sensitivity. PMID:19863272
Human capacitance to dosage imbalance: coping with inefficient selection. PMID:19819908
Plasticity of the chemoreceptor repertoire in Drosophila melanogaster. PMID:19816562
Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function. PMID:19758432
Genetical toxicogenomics in Drosophila identifies master-modulatory loci that are regulated by developmental exposure to lead. PMID:19737576
The effects of caffeine on sleep in Drosophila require PKA activity, but not the adenosine receptor. PMID:19726661
Alcohol sensitivity in Drosophila: translational potential of systems genetics. PMID:19652175
Does the clock make the poison? Circadian variation in response to pesticides. PMID:19649249
Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling. PMID:19640479
Relationship between gene co-expression and sharing of transcription factor binding sites in Drosophila melanogaster. PMID:19633094
The genetic basis of transgressive ovary size in honeybee workers. PMID:19620393
A putative amino acid transporter of the solute carrier 6 family is upregulated by lithium and is required for resistance to lithium toxicity in Drosophila. PMID:19619614
A transcriptional network associated with natural variation in Drosophila aggressive behavior. PMID:19607677
Motif composition, conservation and condition-specificity of single and alternative transcription start sites in the Drosophila genome. PMID:19589141
Curled encodes the Drosophila homolog of the vertebrate circadian deadenylase Nocturnin. PMID:19581445
Drosomycin, an innate immunity peptide of Drosophila melanogaster, interacts with the fly voltage-gated sodium channel. PMID:19574227
Insights into female sperm storage from the spermathecal fluid proteome of the honeybee Apis mellifera. PMID:19538722
Evolutionary dynamics of recently duplicated genes: Selective constraints on diverging paralogs in the Drosophila pseudoobscura genome. PMID:19536449
Unlocking the secrets of the genome. PMID:19536255
RBR ubiquitin ligases: Diversification and streamlining in animal lineages. PMID:19526189
Mutations in many genes affect aggressive behavior in Drosophila melanogaster. PMID:19519879
Identification and validation of housekeeping genes in brains of the desert locust Schistocerca gregaria under different developmental conditions. PMID:19508726
Gene expression during Drosophila melanogaster egg development before and after reproductive diapause. PMID:19463195
Voltage coupling of primary H+ V-ATPases to secondary Na+- or K+-dependent transporters. PMID:19448072
Understanding the neurogenetics of sleep: progress from Drosophila. PMID:19446357
Modulated modularity clustering as an exploratory tool for functional genomic inference. PMID:19424432
Quantitative trait loci for aggressive behavior in Drosophila melanogaster. PMID:19414563
Buffering of segmental and chromosomal aneuploidies in Drosophila melanogaster. PMID:19412336
Genome-wide mapping of boundary element-associated factor (BEAF) binding sites in Drosophila melanogaster links BEAF to transcription. PMID:19380483
Battle and ballet: molecular interactions between the sexes in Drosophila. PMID:19349638
Sox100B, a Drosophila group E Sox-domain gene, is required for somatic testis differentiation. PMID:19339815
Drosophila expresses a CD98 transporter with an evolutionarily conserved structure and amino acid-transport properties. PMID:19335336
The multi-AT-hook chromosomal protein of Drosophila melanogaster, D1, is dispensable for viability. PMID:19293138
Characterization of Drosophila melanogaster cytochrome P450 genes. PMID:19289821
Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes. PMID:19260763
General gene movement off the X chromosome in the Drosophila genus. PMID:19251740
Molecular evolution of the testis TAFs of Drosophila. PMID:19244474
Sex-lethal facilitates the transition from germline stem cell to committed daughter cell in the Drosophila ovary. PMID:19237687
Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep. PMID:19234472
Systems genetics of complex traits in Drosophila melanogaster. PMID:19234471
The B-type lamin is required for somatic repression of testis-specific gene clusters. PMID:19218438
A Drosophila systems model of pentylenetetrazole induced locomotor plasticity responsive to antiepileptic drugs. PMID:19154620
Multipotent stem cells in the Malpighian tubules of adult Drosophila melanogaster. PMID:19151216
Ribosomal s6 kinase cooperates with casein kinase 2 to modulate the Drosophila circadian molecular oscillator. PMID:19144847
Network-level molecular evolutionary analysis of the insulin/TOR signal transduction pathway across 12 Drosophila genomes. PMID:19141596
Sgt1, a co-chaperone of Hsp90 stabilizes Polo and is required for centrosome organization. PMID:19131964
Complex organizational structure of the genome revealed by genome-wide analysis of single and alternative promoters in Drosophila melanogaster. PMID:19128496
Molecular architecture of the centriole proteome: the conserved WD40 domain protein POC1 is required for centriole duplication and length control. PMID:19109428
Mutations in AtPS1 (Arabidopsis thaliana parallel spindle 1) lead to the production of diploid pollen grains. PMID:19043546
Genetic and systems level analysis of Drosophila sticky/citron kinase and dFmr1 mutants reveals common regulation of genetic networks. PMID:19032789
Salty dog, an SLC5 symporter, modulates Drosophila response to salt stress. PMID:19018044
Adult-specific over-expression of the Drosophila genes magu and hebe increases life span and modulates late-age female fecundity. PMID:19011900
Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. PMID:19005568
Polycomb group protein Suppressor 2 of zeste is a functional homolog of Posterior Sex Combs. PMID:18981224
Quality of regulatory elements in Drosophila retrogenes. PMID:18848618
Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster. PMID:18809725
A role for very-long-chain fatty acids in furrow ingression during cytokinesis in Drosophila spermatocytes. PMID:18804373
Evolutionary constraint and adaptation in the metabolic network of Drosophila. PMID:18799713
Maternal Groucho and bHLH repressors amplify the dose-sensitive X chromosome signal in Drosophila sex determination. PMID:18773886
Stability and dynamics of polycomb target sites in Drosophila development. PMID:18773083
Mating induces an immune response and developmental switch in the Drosophila oviduct. PMID:18725632
The dominant cold-sensitive Out-cold mutants of Drosophila melanogaster have novel missense mutations in the voltage-gated sodium channel gene paralytic. PMID:18723887
Cloning of the neurodegeneration gene drop-dead and characterization of additional phenotypes of its mutation. PMID:18719404
The Drosophila protein palmitoylome: characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases. PMID:18719403
Gene expression disruptions of organism versus organ in Drosophila species hybrids. PMID:18714377
A Drosophila Smyd4 homologue is a muscle-specific transcriptional modulator involved in development. PMID:18714374
The soup in my fly: evolution, form and function of seminal fluid proteins. PMID:18666830
Proteomics reveals novel Drosophila seminal fluid proteins transferred at mating. PMID:18666829
Recent origins of sperm genes in Drosophila. PMID:18653731
Identification of SLEEPLESS, a sleep-promoting factor. PMID:18635795
Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. PMID:18588663
On the origin of new genes in Drosophila. PMID:18550802
CRA-1 uncovers a double-strand break-dependent pathway promoting the assembly of central region proteins on chromosome axes during C. elegans meiosis. PMID:18535664
Evolutionary origin of regulatory regions of retrogenes in Drosophila. PMID:18498650
Effects of X-linkage and sex-biased gene expression on the rate of adaptive protein evolution in Drosophila. PMID:18477586
The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila. PMID:18474623
straightjacket is required for the synaptic stabilization of cacophony, a voltage-gated calcium channel alpha1 subunit. PMID:18391075
Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. PMID:18311141
Polyglutamine genes interact to modulate the severity and progression of neurodegeneration in Drosophila. PMID:18271626
Identity and transfer of male reproductive gland proteins of the dengue vector mosquito, Aedes aegypti: potential tools for control of female feeding and reproduction. PMID:18207079
Genome organization and gene expression shape the transposable element distribution in the Drosophila melanogaster euchromatin. PMID:18081425
Variable sexually dimorphic gene expression in laboratory strains of Drosophila melanogaster. PMID:18070343
A portrait of copy-number polymorphism in Drosophila melanogaster. PMID:18056801
Evolution in the fast lane: rapidly evolving sex-related genes in Drosophila. PMID:18039869
The challenges of developing novel antiparasitic drugs. PMID:18004600
Demasculinization of X chromosomes in the Drosophila genus. PMID:17994090
Genome-scale analysis of positionally relocated genes. PMID:17989252
A rapid genome-wide response to Drosophila melanogaster social interactions. PMID:17714588
FlyMine: an integrated database for Drosophila and Anopheles genomics. PMID:17615057 -
FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
PubMed citations: 103.
103 articles citing: FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Decreasing pdzd8-mediated mito-ER contacts improves organismal fitness and mitigates Aβ42 toxicity. PMID:35831024
Corazonin Neurons Contribute to Dimorphic Ethanol Sedation Sensitivity in Drosophila melanogaster. PMID:35814486
Repeated truncation of a modular antimicrobial peptide gene for neural context. PMID:35714143
Inducible Expression of Several Drosophila melanogaster Genes Encoding Juvenile Hormone Binding Proteins by a Plant Diterpene Secondary Metabolite, Methyl Lucidone. PMID:35621756
Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. PMID:35582794
A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females. PMID:35471187
The MicroRNA miR-277 Controls Physiology and Pathology of the Adult Drosophila Midgut by Regulating the Expression of Fatty Acid β-Oxidation-Related Genes in Intestinal Stem Cells. PMID:35448502
TOR signalling is required for host lipid metabolic remodelling and survival following enteric infection in Drosophila. PMID:35363274
FlyBase: a guided tour of highlighted features. PMID:35266522
The life history of Drosophila sperm involves molecular continuity between male and female reproductive tracts. PMID:35254899
Pool-GWAS on reproductive dormancy in Drosophila simulans suggests a polygenic architecture. PMID:35137042
Parallel evolution of a splicing program controlling neuronal excitability in flies and mammals. PMID:35089784
A spatiotemporal atlas of the lepidopteran pest Helicoverpa armigera midgut provides insights into nutrient processing and pH regulation. PMID:35073840
SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In Vivo. PMID:34948211
Intermolecular Interactions Drive Protein Adaptive and Coadaptive Evolution at Both Species and Population Levels. PMID:34878126
Single-nucleus transcriptomes reveal evolutionary and functional properties of cell types in the Drosophila accessory gland. PMID:34849871
Vitamin A deficiency affects gene expression in the Drosophila melanogaster head. PMID:34849795
An integrated host-microbiome response to atrazine exposure mediates toxicity in Drosophila. PMID:34819611
Population biology of accessory gland-expressed de novo genes in Drosophila melanogaster. PMID:34791207
FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas. PMID:34718735
Metabolic gene regulation by Drosophila GATA transcription factor Grain. PMID:34634038
Loss of Stearoyl-CoA desaturase 1 leads to cardiac dysfunction and lipotoxicity. PMID:34423827
Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in Drosophila testis. PMID:34403408
Expression of the foraging gene in adult Drosophila melanogaster. PMID:34382904
Sexual Antagonism, Temporally Fluctuating Selection, and Variable Dominance Affect a Regulatory Polymorphism in Drosophila melanogaster. PMID:34289067
Identification and bioinformatic analysis of neprilysin and neprilysin-like metalloendopeptidases in Drosophila melanogaster. PMID:34189422
Nonadaptive molecular evolution of seminal fluid proteins in Drosophila. PMID:34184267
Discovering signaling mechanisms governing metabolism and metabolic diseases with Drosophila. PMID:34139200
Loss of p21-activated kinase Mbt/PAK4 causes Parkinson-like phenotypes in Drosophila. PMID:34125184
She's got nerve: roles of octopamine in insect female reproduction. PMID:33909537
Drosophila female reproductive tract gene expression reveals coordinated mating responses and rapidly evolving tissue-specific genes. PMID:33890615
Aedes aegypti dyspepsia encodes a novel member of the SLC16 family of transporters and is critical for reproductive fitness. PMID:33826624
The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. PMID:33815151
Mitochondrial genotype alters the impact of rapamycin on the transcriptional response to nutrients in Drosophila. PMID:33761878
The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control. PMID:33750380
Methods and tools for spatial mapping of single-cell RNAseq clusters in Drosophila. PMID:33713129
A neuroendocrine pathway modulating osmotic stress in Drosophila. PMID:33684132
Endosomal Rab GTPases regulate secretory granule maturation in Drosophila larval salivary glands. PMID:33628358
Function of Drosophila Synaptotagmins in membrane trafficking at synapses. PMID:33619613
Functional Diversification, Redundancy, and Epistasis among Paralogs of the Drosophila melanogaster Obp50a-d Gene Cluster. PMID:33560417
Tissue-specific dynamic codon redefinition in Drosophila. PMID:33500350
The Drosophila melanogaster Neprilysin Nepl15 is involved in lipid and carbohydrate storage. PMID:33483521
Transcription Factors Drive Opposite Relationships between Gene Age and Tissue Specificity in Male and Female Drosophila Gonads. PMID:33481021
Investigating cytosolic 5'-nucleotidase II family genes as candidates for neuropsychiatric disorders in Drosophila (114/150 chr). PMID:33462198
The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth. PMID:33370772
The Drosophila E78 nuclear receptor regulates dietary triglyceride uptake and systemic lipid levels. PMID:33368768
RNAi-based screens uncover a potential new role for the orphan neuropeptide receptor Moody in Drosophila female germline stem cell maintenance. PMID:33307547
Reproductive consequences of an extra long-term sperm storage organ. PMID:33256600
A context-dependent bifurcation in the Pointed transcriptional effector network contributes specificity and robustness to retinal cell fate acquisition. PMID:33253156
Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles. PMID:33249988
I-KCKT allows dissection-free RNA profiling of adult Drosophila intestinal progenitor cells. PMID:33246929
A multicomponent screen for feeding behaviour and nutritional status in Drosophila to interrogate mammalian appetite-related genes. PMID:33242659
FlyBase: updates to the Drosophila melanogaster knowledge base. PMID:33219682
Enteric neurons increase maternal food intake during reproduction. PMID:33116314
Leveraging Multiple Layers of Data To Predict Drosophila Complex Traits. PMID:33106232
Interactions between the microbiome and mating influence the female's transcriptional profile in Drosophila melanogaster. PMID:33097776
Mitochondrial-Y chromosome epistasis in Drosophila melanogaster. PMID:33081607
Cytoplasmic sharing through apical membrane remodeling. PMID:33051002
Nuclear translocation ability of Lipin differentially affects gene expression and survival in fed and fasting Drosophila. PMID:32989002
Rosy Beginnings: Studying Peroxisomes in Drosophila. PMID:32984330
Drosophila Insulin-Like Peptide 8 (DILP8) in Ovarian Follicle Cells Regulates Ovulation and Metabolism. PMID:32849266
An autoregulatory switch in sex-specific phf7 transcription causes loss of sexual identity and tumors in the Drosophila female germline. PMID:32816970
Differentiating Drosophila female germ cells initiate Polycomb silencing by regulating PRC2-interacting proteins. PMID:32773039
Polymorphism and Divergence of Novel Gene Expression Patterns in Drosophila melanogaster. PMID:32737121
Systemic and heart autonomous effects of sphingosine Δ4 desaturase deficiency in lipotoxic cardiac pathophysiology. PMID:32641420
Zinc Dynamics during Drosophila Oocyte Maturation and Egg Activation. PMID:32615472
Drosophila Plc21C is involved in calcium wave propagation during egg activation. PMID:32550503
Transposable elements employ distinct integration strategies with respect to transcriptional landscapes in eukaryotic genomes. PMID:32442316
A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord. PMID:32314735
The neuronal receptor tyrosine kinase Alk is a target for longevity. PMID:32291952
Condensin I subunit Cap-G is essential for proper gene expression during the maturation of post-mitotic neurons. PMID:32255428
The conserved regulatory basis of mRNA contributions to the early Drosophila embryo differs between the maternal and zygotic genomes. PMID:32226006
The fruitless gene affects female receptivity and species isolation. PMID:32208837
Sugar-Induced Obesity and Insulin Resistance Are Uncoupled from Shortened Survival in Drosophila. PMID:32197072
TMT-Based Quantitative Proteomic Profiling of Overwintering Lissorhoptrus oryzophilus. PMID:32038298
How to turn an organism into a model organism in 10 'easy' steps. PMID:32034051
A transcriptomic and proteomic atlas of expression in the Nezara viridula (Heteroptera: Pentatomidae) midgut suggests the compartmentalization of xenobiotic metabolism and nutrient digestion. PMID:32028881
A role for triglyceride lipase brummer in the regulation of sex differences in Drosophila fat storage and breakdown. PMID:31961851
Significance of DopEcR, a G-protein coupled dopamine/ecdysteroid receptor, in physiological and behavioral response to stressors. PMID:31955616
The septate junction protein Mesh is required for epithelial morphogenesis, ion transport, and paracellular permeability in the Drosophila Malpighian tubule. PMID:31913700
Specialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubule. PMID:31907321
Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary. PMID:31558581
Knockdown of APOPT1/COA8 Causes Cytochrome c Oxidase Deficiency, Neuromuscular Impairment, and Reduced Resistance to Oxidative Stress in Drosophila melanogaster. PMID:31555154
Insights into the Functions of LncRNAs in Drosophila. PMID:31546813
Sex Differences in Intestinal Carbohydrate Metabolism Promote Food Intake and Sperm Maturation. PMID:31398343
De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia. PMID:31327508
Self-sperm induce resistance to the detrimental effects of sexual encounters with males in hermaphroditic nematodes. PMID:31282863
The Drosophila Malpighian tubule as a model for mammalian tubule function. PMID:31268918
Come Fly with Me: An overview of dopamine receptors in Drosophila melanogaster. PMID:31219669
Female Genetic Contributions to Sperm Competition in Drosophila melanogaster. PMID:31101677
Two modes of transvection at the eyes absent gene of Drosophila demonstrate plasticity in transcriptional regulatory interactions in cis and in trans. PMID:31075100
Widespread gene duplication and adaptive evolution in the RNA interference pathways of the Drosophila obscura group. PMID:31068148
Studying alcohol use disorder using Drosophila melanogaster in the era of 'Big Data'. PMID:30992041
The diverse small proteins called odorant-binding proteins. PMID:30977439
Codon Usage Differences among Genes Expressed in Different Tissues of Drosophila melanogaster. PMID:30859203
Loss of miR-210 leads to progressive retinal degeneration in Drosophila melanogaster. PMID:30670478
RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stress. PMID:30651069
Composition of the Survival Motor Neuron (SMN) Complex in Drosophila melanogaster. PMID:30563832
G protein-coupled receptors in arthropod vectors: omics and pharmacological approaches to elucidate ligand-receptor interactions and novel organismal functions. PMID:30551818
RNA-on-X 1 and 2 in Drosophila melanogaster fulfill separate functions in dosage compensation. PMID:30532158
The BioGRID interaction database: 2019 update. PMID:30476227
The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells. PMID:30297796
Regulation of the X Chromosome in the Germline and Soma of Drosophila melanogaster Males. PMID:29734690 -
FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster
PubMed citations: 86.
86 articles citing: FlyAtlas: database of gene expression in the tissues of Drosophila melanogaster
ATP-sensitive inward rectifier potassium channels reveal functional linkage between salivary gland function and blood feeding in the mosquito, Aedes aegypti. PMID:35347209
FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas. PMID:34718735
Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts. PMID:34622778
Genome-wide analysis in Drosophila reveals diet-by-gene interactions and uncovers diet-responsive genes. PMID:34568906
The Drosophila Baramicin polypeptide gene protects against fungal infection. PMID:34432851
Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila. PMID:34201304
Discovering signaling mechanisms governing metabolism and metabolic diseases with Drosophila. PMID:34139200
Conservation and diversity of the eukaryotic SAGA coactivator complex across kingdoms. PMID:34112237
The Importance of Drosophila melanogaster Research to UnCover Cellular Pathways Underlying Parkinson's Disease. PMID:33800736
Exploiting the Potential of Drosophila Models in Lysosomal Storage Disorders: Pathological Mechanisms and Drug Discovery. PMID:33800050
CG4928 Is Vital for Renal Function in Fruit Flies and Membrane Potential in Cells: A First In-Depth Characterization of the Putative Solute Carrier UNC93A. PMID:33163493
An autoregulatory switch in sex-specific phf7 transcription causes loss of sexual identity and tumors in the Drosophila female germline. PMID:32816970
mRNA localization mediates maturation of cytoplasmic cilia in Drosophila spermatogenesis. PMID:32706373
Analysing bioelectrical phenomena in the Drosophila ovary with genetic tools: tissue-specific expression of sensors for membrane potential and intracellular pH, and RNAi-knockdown of mechanisms involved in ion exchange. PMID:32635900
Temporal specificity and heterogeneity of Drosophila immune cells. PMID:32162708
Physiology, Development, and Disease Modeling in the Drosophila Excretory System. PMID:32029579
The Drosophila Post-mating Response: Gene Expression and Behavioral Changes Reveal Perdurance and Variation in Cross-Tissue Interactions. PMID:31907222
Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary. PMID:31558581
Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity. PMID:31235842
Electrochemical patterns during Drosophila oogenesis: ion-transport mechanisms generate stage-specific gradients of pH and membrane potential in the follicle-cell epithelium. PMID:31226923
Functional analysis of Aarf domain-containing kinase 1 in Drosophila melanogaster. PMID:31175694
The α/β-hydrolase domain-containing 4- and 5-related phospholipase Pummelig controls energy storage in Drosophila. PMID:31164391
Autophagy accounts for approximately one-third of mitochondrial protein turnover and is protein selective. PMID:30865561
Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. PMID:30774648
Peroxisome-associated Sgroppino links fat metabolism with survival after RNA virus infection in Drosophila. PMID:30765784
Drosophila Models of Sporadic Parkinson's Disease. PMID:30373150
The gut microbiome participates in transgenerational inheritance of low-temperature responses in Drosophila melanogaster. PMID:30372516
Fire ant social chromosomes: Differences in number, sequence and expression of odorant binding proteins. PMID:30283649
Glucocerebrosidase deficiency promotes protein aggregation through dysregulation of extracellular vesicles. PMID:30256786
GDAP2 mutations implicate susceptibility to cellular stress in a new form of cerebellar ataxia. PMID:30084953
A plant diterpene counteracts juvenile hormone-mediated gene regulation during Drosophila melanogaster larval development. PMID:30011330
Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP. PMID:29743191
Modeling Parkinson's Disease in Drosophila: What Have We Learned for Dominant Traits? PMID:29686647
Conservation of cardiac L-type Ca2+ channels and their regulation in Drosophila: A novel genetically-pliable channelopathic model. PMID:29684406
Adult functions for the Drosophila DHR78 nuclear receptor. PMID:29171103
Physiological characterization and regulation of the contractile properties of the mosquito ventral diverticulum (crop). PMID:29107658
A Complex Relationship between Immunity and Metabolism in Drosophila Diet-Induced Insulin Resistance. PMID:29084810
FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data. PMID:29069479
Partitioning the roles of CYP6G1 and gut microbes in the metabolism of the insecticide imidacloprid in Drosophila melanogaster. PMID:28900131
Variation in DNA Methylation Is Not Consistently Reflected by Sociality in Hymenoptera. PMID:28854636
Naturally Segregating Variation at Ugt86Dd Contributes to Nicotine Resistance in Drosophila melanogaster. PMID:28743761
The Narrow Abdomen Ion Channel Complex Is Highly Stable and Persists from Development into Adult Stages to Promote Behavioral Rhythmicity. PMID:28634443
Age-dependent diastolic heart failure in an in vivo Drosophila model. PMID:28328397
A Mesh-Duox pathway regulates homeostasis in the insect gut. PMID:28248301
Drosophila divalent metal ion transporter Malvolio is required in dopaminergic neurons for feeding decisions. PMID:28220999
A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin. PMID:27852774
Using FlyBase, a Database of Drosophila Genes and Genomes. PMID:27730573
A widely employed germ cell marker is an ancient disordered protein with reproductive functions in diverse eukaryotes. PMID:27718356
Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster. PMID:27599372
Neurons That Underlie Drosophila melanogaster Reproductive Behaviors: Detection of a Large Male-Bias in Gene Expression in fruitless-Expressing Neurons. PMID:27247289
flyDIVaS: A Comparative Genomics Resource for Drosophila Divergence and Selection. PMID:27226167
The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules. PMID:27072072
Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila. PMID:27058248
Expression patterns of cysteine peptidase genes across the Tribolium castaneum life cycle provide clues to biological function. PMID:26819843
The Matrix Proteins Hasp and Hig Exhibit Segregated Distribution within Synaptic Clefts and Play Distinct Roles in Synaptogenesis. PMID:26758847
Genomic signatures of domestication on neurogenetic genes in Drosophila melanogaster. PMID:26728183
Genetics on the Fly: A Primer on the Drosophila Model System. PMID:26564900
The novel ABC transporter ABCH1 is a potential target for RNAi-based insect pest control and resistance management. PMID:26333918
Transport proteins NHA1 and NHA2 are essential for survival, but have distinct transport modalities. PMID:26324901
Selection Against Maternal microRNA Target Sites in Maternal Transcripts. PMID:26306531
Identification and functional analysis of early gene expression induced by circadian light-resetting in Drosophila. PMID:26231660
Comparisons between Arabidopsis thaliana and Drosophila melanogaster in relation to Coding and Noncoding Sequence Length and Gene Expression. PMID:26114098
Behavioral idiosyncrasy reveals genetic control of phenotypic variability. PMID:25953335
Maintenance of glia in the optic lamina is mediated by EGFR signaling by photoreceptors in adult Drosophila. PMID:25909451
Linking gene expression to phenotypes via pathway information. PMID:25901272
Tracing the evolutionary origins of insect renal function. PMID:25896425
Pervasive variation of transcription factor orthologs contributes to regulatory network evolution. PMID:25748510
SuperFly: a comparative database for quantified spatio-temporal gene expression patterns in early dipteran embryos. PMID:25404137
Transcriptome-based identification of ABC transporters in the western tarnished plant bug Lygus hesperus. PMID:25401762
Targeted inactivation of the rickets receptor in muscle compromises Drosophila viability. PMID:25278473
Spermitin: a novel mitochondrial protein in Drosophila spermatids. PMID:25265054
Chloride channels in stellate cells are essential for uniquely high secretion rates in neuropeptide-stimulated Drosophila diuresis. PMID:25228763
Phylogenetic analyses and characterization of RNase X25 from Drosophila melanogaster suggest a conserved housekeeping role and additional functions for RNase T2 enzymes in protostomes. PMID:25133712
Cloning and characterization of a novel Drosophila stress induced DNase. PMID:25083901
Galactokinase is a novel modifier of calcineurin-induced cardiomyopathy in Drosophila. PMID:25081566
Transcriptional regionalization of the fruit fly's airway epithelium. PMID:25020150
Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. PMID:24981863
Genetic dissection of the Drosophila melanogaster female head transcriptome reveals widespread allelic heterogeneity. PMID:24810915
The four aldehyde oxidases of Drosophila melanogaster have different gene expression patterns and enzyme substrate specificities. PMID:24737760
Resources for functional genomics studies in Drosophila melanogaster. PMID:24653003
Natural antisense transcripts regulate the neuronal stress response and excitability. PMID:24642409
High intake of dietary sugar enhances bisphenol A (BPA) disruption and reveals ribosome-mediated pathways of toxicity. PMID:24614930
SelR reverses Mical-mediated oxidation of actin to regulate F-actin dynamics. PMID:24212093
Male-specific Fruitless isoforms have different regulatory roles conferred by distinct zinc finger DNA binding domains. PMID:24074028
Data-mining the FlyAtlas online resource to identify core functional motifs across transporting epithelia. PMID:23895496
A burst of ABC genes in the genome of the polyphagous spider mite Tetranychus urticae. PMID:23663308 - http://dx.doi.org/10.1093/nar/gkx976
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human and other vertebrate genomes
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version: extracted_at: 2022-11-04T11:16:25.468657
invertebrate genome databases
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dna microarray
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micro rna
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microarray experiment
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rna sequencing
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human and other vertebrate genomes
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
invertebrate genome databases
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dna microarray micro rna microarray experiment rna sequence human and other vertebrate genomes invertebrate genome
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