TubercuList
Knowledge base integrates genome details, protein information, drug and transcriptome data, mutant and operon annotation, bibliography, structural views and comparative genomics, in a structured manner required for the rational development of new diagnostic, therapeutic and prophylactic measures against tuberculosis. With the means of expert curation and continuous updates, we deliver a broad view of the Mycobacterium tuberculosis genome.
Description
More detailed information about this field from each metasource.
Knowledge base integrates genome details, protein information, drug and transcriptome data, mutant and operon annotation, bibliography, structural views and comparative genomics, in a structured manner required for the rational development of new diagnostic, therapeutic and prophylactic measures against tuberculosis. With the means of expert curation and continuous updates, we deliver a broad view of the Mycobacterium tuberculosis genome.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:34.836091
Webpage:
http://genolist.pasteur.fr/TubercuList/Webpage
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http://genolist.pasteur.fr/TubercuList/
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:32:34.836091
Publications:
Publications
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TubercuList--10 years after
PMID: 20980199
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:34.836091
Publications
More detailed information about this field from each metasource.
TubercuList--10 years after
PMID: 20980199
metasource: bio.tools
version: extracted_at: 2022-11-04T11:32:34.836091
-
TubercuList--10 years after
PubMed citations: 203.
203 articles citing: TubercuList--10 years after
An In Vivo Model of Separate M. tuberculosis Phagocytosis by Neutrophils and Macrophages: Gene Expression Profiles in the Parasite and Disease Development in the Mouse Host. PMID:35328388
Host- and Age-Dependent Transcriptional Changes in Mycobacterium tuberculosis Cell Envelope Biosynthesis Genes after Exposure to Human Alveolar Lining Fluid. PMID:35055170
An evolutionary functional genomics approach identifies novel candidate regions involved in isoniazid resistance in Mycobacterium tuberculosis. PMID:34819627
Structure-Aware Mycobacterium tuberculosis Functional Annotation Uncloaks Resistance, Metabolic, and Virulence Genes. PMID:34726489
Genotypic and phenotypic diversity of Mycobacterium tuberculosis complex genotypes prevalent in West Africa. PMID:34437584
Mycobacterium tuberculosis complex lineage 5 exhibits high levels of within-lineage genomic diversity and differing gene content compared to the type strain H37Rv. PMID:34241588
Transcriptional adaptation of Mycobacterium ulcerans in an original mouse model: New insights into the regulation of mycolactone. PMID:34107844
Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis. PMID:33950161
Computational evaluation of anticipated PE_PGRS39 protein involvement in host-pathogen interplay and its integration into vaccine development. PMID:33824847
Genome analyses of 174 strains of Mycobacterium tuberculosis provide insight into the evolution of drug resistance and reveal potential drug targets. PMID:33750515
Mapping Gene-by-Gene Single-Nucleotide Variation in 8,535 Mycobacterium tuberculosis Genomes: a Resource To Support Potential Vaccine and Drug Development. PMID:33692198
A Multi-Pronged Computational Pipeline for Prioritizing Drug Target Strategies for Latent Tuberculosis. PMID:33381491
Systematic Evaluation of Mycobacterium tuberculosis Proteins for Antigenic Properties Identifies Rv1485 and Rv1705c as Potential Protective Subunit Vaccine Candidates. PMID:33318140
Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis. PMID:33283973
Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis. PMID:33199862
Drivers and sites of diversity in the DNA adenine methylomes of 93 Mycobacterium tuberculosis complex clinical isolates. PMID:33107429
The crystal structure of mycobacterial epoxide hydrolase A. PMID:33024154
Characterization of Genomic Variants Associated with Resistance to Bedaquiline and Delamanid in Naive Mycobacterium tuberculosis Clinical Strains. PMID:32907992
High-Throughput Screen for Cell Wall Synthesis Network Module in Mycobacterium tuberculosis Based on Integrated Bioinformatics Strategy. PMID:32695753
Two interacting ATPases protect Mycobacterium tuberculosis from glycerol and nitric oxide toxicity. PMID:32482725
Homoplastic single nucleotide polymorphisms contributed to phenotypic diversity in Mycobacterium tuberculosis. PMID:32415151
Comparative genomics shows differences in the electron transport and carbon metabolic pathways of Mycobacterium africanum relative to Mycobacterium tuberculosis and suggests an adaptation to low oxygen tension. PMID:32090860
Comprehensive analysis of iron utilization by Mycobacterium tuberculosis. PMID:32069330
A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic. PMID:32014024
PA0335, a Gene Encoding Histidinol Phosphate Phosphatase, Mediates Histidine Auxotrophy in Pseudomonas aeruginosa. PMID:31862725
Computational pan-genome mapping and pairwise SNP-distance improve detection of Mycobacterium tuberculosis transmission clusters. PMID:31815935
Transcriptional signatures of Mycobacterium tuberculosis in mouse model of intraocular tuberculosis. PMID:31504463
Design and Construction of a Eukaryotic Cloning Vector Encoding the mpt51 Gene of Mycobacterium tuberculosis. PMID:31334285
An essential bifunctional enzyme in Mycobacterium tuberculosis for itaconate dissimilation and leucine catabolism. PMID:31320588
On the Impact of the Pangenome and Annotation Discrepancies While Building Protein Sequence Databases for Bacteria Proteogenomics. PMID:31281302
Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways. PMID:31239393
CarD contributes to diverse gene expression outcomes throughout the genome of Mycobacterium tuberculosis. PMID:31217290
Metabolomics Studies To Decipher Stress Responses in Mycobacterium smegmatis Point to a Putative Pathway of Methylated Amine Biosynthesis. PMID:31138627
Mycobacterium smegmatis HtrA Blocks the Toxic Activity of a Putative Cell Wall Amidase. PMID:31116989
Molecular epidemiology and whole genome sequencing analysis of clinical Mycobacterium bovis from Ghana. PMID:30830912
Evidence for Highly Variable, Region-Specific Patterns of T-Cell Epitope Mutations Accumulating in Mycobacterium tuberculosis Strains. PMID:30814998
Designing and Construction of a Cloning Vector Encoding mtb32C and mpt51 Fragments of Mycobacterium tuberculosis as a DNA Vaccine Candidate. PMID:30774678
Mycobacterium tuberculosis Rv0366c-Rv0367c encodes a non-canonical PezAT-like toxin-antitoxin pair. PMID:30718534
Genome-wide mapping of Topoisomerase I activity sites reveal its role in chromosome segregation. PMID:30566665
Rv1288, a Two Domain, Cell Wall Anchored, Nutrient Stress Inducible Carboxyl-Esterase of Mycobacterium tuberculosis, Modulates Cell Wall Lipid. PMID:30560095
A Systematic Review on Novel Mycobacterium tuberculosis Antigens and Their Discriminatory Potential for the Diagnosis of Latent and Active Tuberculosis. PMID:30473692
A phylogenomic study quantifies competing mechanisms for pseudogenization in prokaryotes-The Mycobacterium leprae case. PMID:30383852
New epidemic cluster of pre-extensively drug resistant isolates of Mycobacterium tuberculosis Ural family emerging in Eastern Europe. PMID:30348088
The relationship between transmission time and clustering methods in Mycobacterium tuberculosis epidemiology. PMID:30341041
Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis. PMID:30337649
Transcriptional Profile of Mycobacterium tuberculosis in an in vitro Model of Intraocular Tuberculosis. PMID:30333960
AbmR (Rv1265) is a novel transcription factor of Mycobacterium tuberculosis that regulates host cell association and expression of the non-coding small RNA Mcr11. PMID:30207611
PE-only/PE_PGRS proteins of Mycobacterium tuberculosis contain a conserved tetra-peptide sequence DEVS/DXXS that is a potential caspase-3 cleavage motif. PMID:30207307
Construction of an overexpression library for Mycobacterium tuberculosis. PMID:30197930
A Major Mycobacterium tuberculosis outbreak caused by one specific genotype in a low-incidence country: Exploring gene profile virulence explanations. PMID:30089859
Understanding the role of interactions between host and Mycobacterium tuberculosis under hypoxic condition: an in silico approach. PMID:30053801
Comparative genomics of Mycobacterium africanum Lineage 5 and Lineage 6 from Ghana suggests distinct ecological niches. PMID:30050166
Whole genome SNP analysis suggests unique virulence factor differences of the Beijing and Manila families of Mycobacterium tuberculosis found in Hawaii. PMID:30036392
Unexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and Immunogenicity. PMID:30010947
The BCGΔBCG1419c Vaccine Candidate Reduces Lung Pathology, IL-6, TNF-α, and IL-10 During Chronic TB Infection. PMID:29946316
Modeling leaderless transcription and atypical genes results in more accurate gene prediction in prokaryotes. PMID:29773659
Identification and structural characterization of a histidinol phosphate phosphatase from Mycobacterium tuberculosis. PMID:29752410
Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA). PMID:29728457
Adipocyte Model of Mycobacterium tuberculosis Infection Reveals Differential Availability of Iron to Bacilli in the Lipid-Rich Caseous Environment. PMID:29632245
Second-line anti-tuberculosis drug resistance testing in Ghana identifies the first extensively drug-resistant tuberculosis case. PMID:29503573
Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity. PMID:29491462
Isoniazid resistance levels of Mycobacterium tuberculosis can largely be predicted by high-confidence resistance-conferring mutations. PMID:29459669
The transcriptome of Mycobacterium tuberculosis in a lipid-rich dormancy model through RNAseq analysis. PMID:29247215
Insights from the protein-protein interaction network analysis of Mycobacterium tuberculosis toxin-antitoxin systems. PMID:29225431
TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species. PMID:29220433
Cloning, optimization of induction conditions and purification of Mycobacterium tuberculosis Rv1733c protein expressed in Escherichia coli. PMID:29213997
Rv0004 is a new essential member of the mycobacterial DNA replication machinery. PMID:29176877
A genome-wide structure-based survey of nucleotide binding proteins in M. tuberculosis. PMID:28970579
Fitness-compensatory mutations facilitate the spread of drug-resistant F15/LAM4/KZN and F28 Mycobacterium tuberculosis strains in KwaZulu-Natal, South Africa. PMID:28947708
Nε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains: Proteins Involved in Bioenergetics, Virulence, and Antimicrobial Resistance Are Acetylated. PMID:28920697
Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis. PMID:28893793
Decoding the similarities and differences among mycobacterial species. PMID:28854187
Identification of novel antigen candidates for a tuberculosis vaccine in the adult zebrafish (Danio rerio). PMID:28742838
Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions. PMID:28720801
β-CA-specific inhibitor dithiocarbamate Fc14-584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis. PMID:28629306
Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads. PMID:28594827
The Ser/Thr Protein Kinase Protein-Protein Interaction Map of M. tuberculosis. PMID:28572091
Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum. PMID:28454650
The EXIT Strategy: an Approach for Identifying Bacterial Proteins Exported during Host Infection. PMID:28442606
Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c). PMID:28346784
Protein Bioinformatics Databases and Resources. PMID:28150231
Mutation in an Unannotated Protein Confers Carbapenem Resistance in Mycobacterium tuberculosis. PMID:28069655
Inhibition of apoptosis by Rv2456c through Nuclear factor-κB extends the survival of Mycobacterium tuberculosis. PMID:27931684
Genome scale identification, structural analysis, and classification of periplasmic binding proteins from Mycobacterium tuberculosis. PMID:27858159
Unique Regulation of the DosR Regulon in the Beijing Lineage of Mycobacterium tuberculosis. PMID:27799329
Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages. PMID:27798628
Universal stress protein Rv2624c alters abundance of arginine and enhances intracellular survival by ATP binding in mycobacteria. PMID:27762279
Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis. PMID:27573104
Whole genome sequencing reveals mycobacterial microevolution among concurrent isolates from sputum and blood in HIV infected TB patients. PMID:27495002
Crystal structure of Rv3899c(184-410), a hypothetical protein from Mycobacterium tuberculosis. PMID:27487929
Detection and characterization of drug-resistant conferring genes in Mycobacterium tuberculosis complex strains: A prospective study in two distant regions of Ghana. PMID:27450017
REMap: Operon map of M. tuberculosis based on RNA sequence data. PMID:27450008
A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans. PMID:27409590
Macrophage Immune Response Suppression by Recombinant Mycobacterium tuberculosis Antigens, the ESAT-6, CFP-10, and ESAT-6/CFP-10 Fusion Proteins. PMID:27365551
Proteome analysis of the Mycobacterium tuberculosis Beijing B0/W148 cluster. PMID:27356881
Biochemical evidence for relaxed substrate specificity of Nα-acetyltransferase (Rv3420c/rimI) of Mycobacterium tuberculosis. PMID:27353550
Cooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD. PMID:27342278
Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars. PMID:27335320
Paradoxical Hypersusceptibility of Drug-resistant Mycobacteriumtuberculosis to β-lactam Antibiotics. PMID:27333036
Computational recognition and analysis of hitherto uncharacterized nucleotide cyclase-like proteins in bacteria. PMID:27246835
Cultural, Transcriptomic, and Proteomic Analyses of Water-Stressed Cells of Actinobacterial Strains Isolated from Compost: Ecological Implications in the Fed-Batch Composting Process. PMID:27246805
Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance. PMID:27005572
Integration of Metabolic Modeling with Gene Co-expression Reveals Transcriptionally Programmed Reactions Explaining Robustness in Mycobacterium tuberculosis. PMID:27000948
Multiscale Model of Mycobacterium tuberculosis Infection Maps Metabolite and Gene Perturbations to Granuloma Sterilization Predictions. PMID:26975995
Identifying Likely Transmission Pathways within a 10-Year Community Outbreak of Tuberculosis by High-Depth Whole Genome Sequencing. PMID:26938641
Understanding HIV-Mycobacteria synergism through comparative proteomics of intra-phagosomal mycobacteria during mono- and HIV co-infection. PMID:26916387
Genetic features of Mycobacterium tuberculosis modern Beijing sublineage. PMID:26905026
Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis. PMID:26856535
Systematic Survey of Serine Hydrolase Activity in Mycobacterium tuberculosis Defines Changes Associated with Persistence. PMID:26853625
An orphaned Mce-associated membrane protein of Mycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters. PMID:26712165
MycoBASE: expanding the functional annotation coverage of mycobacterial genomes. PMID:26704706
Population tailored modification of tuberculosis specific interferon-gamma release assay. PMID:26632326
M. tuberculosis T Cell Epitope Analysis Reveals Paucity of Antigenic Variation and Identifies Rare Variable TB Antigens. PMID:26607161
Dormant non-culturable Mycobacterium tuberculosis retains stable low-abundant mRNA. PMID:26573524
Mycobacteria modulate host epigenetic machinery by Rv1988 methylation of a non-tail arginine of histone H3. PMID:26568365
Diversity of Mycobacterium tuberculosis across Evolutionary Scales. PMID:26562841
Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates. PMID:26496891
Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations. PMID:26487098
GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis. PMID:26369580
Mycobacterium tuberculosis Is a Natural Ornithine Aminotransferase (rocD) Mutant and Depends on Rv2323c for Growth on Arginine. PMID:26368558
Characterization of a cAMP responsive transcription factor, Cmr (Rv1675c), in TB complex mycobacteria reveals overlap with the DosR (DevR) dormancy regulon. PMID:26358810
Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides. PMID:26324178
Computational evaluation of phytocompounds for combating drug resistant tuberculosis by multi-targeted therapy. PMID:26323856
LytB1 and LytB2 of Mycobacterium tuberculosis Are Not Genetically Redundant. PMID:26309039
Mutation of Rv2887, a marR-like gene, confers Mycobacterium tuberculosis resistance to an imidazopyridine-based agent. PMID:26303802
Selective enrichment of mycobacterial proteins from infected host macrophages. PMID:26303024
A side-by-side comparison of T cell reactivity to fifty-nine Mycobacterium tuberculosis antigens in diverse populations from five continents. PMID:26277695
POTION: an end-to-end pipeline for positive Darwinian selection detection in genome-scale data through phylogenetic comparison of protein-coding genes. PMID:26231214
Distinct Responses of Mycobacterium smegmatis to Exposure to Low and High Levels of Hydrogen Peroxide. PMID:26225431
Analysis of IS6110 insertion sites provide a glimpse into genome evolution of Mycobacterium tuberculosis. PMID:26215170
SInCRe-structural interactome computational resource for Mycobacterium tuberculosis. PMID:26130660
A comprehensive map of genome-wide gene regulation in Mycobacterium tuberculosis. PMID:25977815
Role of intragenic binding of cAMP responsive protein (CRP) in regulation of the succinate dehydrogenase genes Rv0249c-Rv0247c in TB complex mycobacteria. PMID:25940627
Identification of novel Mycobacterium tuberculosis CD4 T-cell antigens via high throughput proteome screening. PMID:25857935
CHOPIN: a web resource for the structural and functional proteome of Mycobacterium tuberculosis. PMID:25833954
The interaction of mycobacterial protein Rv2966c with host chromatin is mediated through non-CpG methylation and histone H3/H4 binding. PMID:25824946
Label-free Quantitative Proteomics Reveals a Role for the Mycobacterium tuberculosis SecA2 Pathway in Exporting Solute Binding Proteins and Mce Transporters to the Cell Wall. PMID:25813378
Using a Label Free Quantitative Proteomics Approach to Identify Changes in Protein Abundance in Multidrug-Resistant Mycobacterium tuberculosis. PMID:25805910
Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: expanding the mycobacterial phosphoproteome catalog. PMID:25713560
The future for early-stage tuberculosis drug discovery. PMID:25689534
Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice. PMID:25658098
Molecular insights into the binding of coenzyme F420 to the conserved protein Rv1155 from Mycobacterium tuberculosis. PMID:25644473
The DNA-binding network of Mycobacterium tuberculosis. PMID:25581030
A phylogeny-based sampling strategy and power calculator informs genome-wide associations study design for microbial pathogens. PMID:25484920
Potential mechanism of action of meso-dihydroguaiaretic acid on Mycobacterium tuberculosis H37Rv. PMID:25474289
Far-red fluorogenic probes for esterase and lipase detection. PMID:25469918
Consequences of genomic diversity in Mycobacterium tuberculosis. PMID:25453224
Identifying feasible metabolic routes in Mycobacterium smegmatis and possible alterations under diverse nutrient conditions. PMID:25403821
Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network. PMID:25380655
Pathogen-derived biomarkers for active tuberculosis diagnosis. PMID:25368609
KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes. PMID:25297886
Integration of heterogeneous molecular networks to unravel gene-regulation in Mycobacterium tuberculosis. PMID:25279447
Whole-Genome Sequences of Two Clinical Isolates of Extensively Drug-Resistant Mycobacterium tuberculosis from Zunyi, China. PMID:25237021
Characterizing the pocketome of Mycobacterium tuberculosis and application in rationalizing polypharmacological target selection. PMID:25220818
Objective: biochemical function. PMID:25071837
Detecting novel genetic variants associated with isoniazid-resistant Mycobacterium tuberculosis. PMID:25025225
Disclosure of selective advantages in the "modern" sublineage of the Mycobacterium tuberculosis Beijing genotype family by quantitative proteomics. PMID:25022876
Disruption of Mycobacterium avium subsp. paratuberculosis-specific genes impairs in vivo fitness. PMID:24885784
The PhoP-dependent ncRNA Mcr7 modulates the TAT secretion system in Mycobacterium tuberculosis. PMID:24874799
TuberQ: a Mycobacterium tuberculosis protein druggability database. PMID:24816183
Genome-wide Mycobacterium tuberculosis variation (GMTV) database: a new tool for integrating sequence variations and epidemiology. PMID:24767249
Mycobacterium tuberculosis pili (MTP), a putative biomarker for a tuberculosis diagnostic test. PMID:24721207
Definition of CD4 Immunosignatures Associated with MTB. PMID:24715893
An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3. PMID:24709835
Biofragments: an approach towards predicting protein function using biologically related fragments and its application to Mycobacterium tuberculosis CYP126. PMID:24677424
Pathogen roid rage: cholesterol utilization by Mycobacterium tuberculosis. PMID:24611808
Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism. PMID:24569628
Systems biology-based identification of Mycobacterium tuberculosis persistence genes in mouse lungs. PMID:24549847
Mycobacterium tuberculosis pellicles express unique proteins recognized by the host humoral response. PMID:24453174
Tuberculosis drug discovery in the post-post-genomic era. PMID:24401837
Functional characterization of two members of histidine phosphatase superfamily in Mycobacterium tuberculosis. PMID:24330471
A multi-level multi-scale approach to study essential genes in Mycobacterium tuberculosis. PMID:24308365
Metabolomics analysis identifies d-Alanine-d-Alanine ligase as the primary lethal target of d-Cycloserine in mycobacteria. PMID:24303782
Genome-wide mapping of transcriptional start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosis. PMID:24268774
Mapping of genotype-phenotype diversity among clinical isolates of mycobacterium tuberculosis by sequence-based transcriptional profiling. PMID:24115728
Phenotypic profiling of Mycobacterium tuberculosis EspA point mutants reveals that blockage of ESAT-6 and CFP-10 secretion in vitro does not always correlate with attenuation of virulence. PMID:24078612
Perturbation of cytochrome c maturation reveals adaptability of the respiratory chain in Mycobacterium tuberculosis. PMID:24045640
Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis. PMID:23995135
Development of an unbiased antigen-mining approach to identify novel vaccine antigens and diagnostic reagents for bovine tuberculosis. PMID:23986315
Identification of novel adhesins of M. tuberculosis H37Rv using integrated approach of multiple computational algorithms and experimental analysis. PMID:23922800
Overexpression of the Rv0805 phosphodiesterase elicits a cAMP-independent transcriptional response. PMID:23835087
Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay. PMID:23794563
Evolution of smooth tubercle Bacilli PE and PE_PGRS genes: evidence for a prominent role of recombination and imprint of positive selection. PMID:23705005
The Mtb proteome library: a resource of assays to quantify the complete proteome of Mycobacterium tuberculosis. PMID:23684311
Analysis of the secretome and identification of novel constituents from culture filtrate of bacillus Calmette-Guerin using high-resolution mass spectrometry. PMID:23616670
A chemical proteomics approach to profiling the ATP-binding proteome of Mycobacterium tuberculosis. PMID:23462205
Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset. PMID:23358848
Identification of widespread adenosine nucleotide binding in Mycobacterium tuberculosis. PMID:23352146
Database resources for the tuberculosis community. PMID:23332401
Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins. PMID:23209251
Computational genomics-proteomics and Phylogeny analysis of twenty one mycobacterial genomes (Tuberculosis & non Tuberculosis strains). PMID:22929624
Topological effects of data incompleteness of gene regulatory networks. PMID:22920968
A point mutation in cycA partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis BCG vaccine strains. PMID:22912881
Crowd sourcing a new paradigm for interactome driven drug target identification in Mycobacterium tuberculosis. PMID:22808064
Annotation of the M. tuberculosis hypothetical orfeome: adding functional information to more than half of the uncharacterized proteins. PMID:22485162
Clinical research and development of tuberculosis diagnostics: moving from silos to synergy. PMID:22476718
Surface proteome of "Mycobacterium avium subsp. hominissuis" during the early stages of macrophage infection. PMID:22392927
Mycobacterium tuberculosis RNA Expression Patterns in Sputum Bacteria Indicate Secreted Esx Factors Contributing to Growth are Highly Expressed in Active Disease. PMID:22291682
Adenylating enzymes in Mycobacterium tuberculosis as drug targets. PMID:22283817
TDR Targets: a chemogenomics resource for neglected diseases. PMID:22116064
Structural annotation of Mycobacterium tuberculosis proteome. PMID:22073123
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry. PMID:21969609
Proteins with complex architecture as potential targets for drug design: a case study of Mycobacterium tuberculosis. PMID:21814507
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