TADB

Names
More detailed information about this field from each metasource.

TADB
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:55.397797

tadb
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:55.397797

Other names: tadb

Type II Toxin-Antitoxin loci in bacteria and archaea

Webpage:

http://bioinfo-mml.sjtu.edu.cn/TADB/

Publications:

Publications
More detailed information about this field from each metasource.

TADB: a web-based resource for Type 2 toxin-antitoxin loci in bacteria and archaea
PMID: 20929871
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:55.397797

http://dx.doi.org/10.1093/nar/gkq908
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

TADB: a web-based resource for Type 2 toxin-antitoxin loci in bacteria and archaea PubMed citations: 138.

138 articles citing: TADB: a web-based resource for Type 2 toxin-antitoxin loci in bacteria and archaea

Thymidine utilisation pathway is a novel phenotypic switch of Mycoplasma hominis. PMID:35037614
Biology and evolution of bacterial toxin-antitoxin systems. PMID:34975154
Genome analysis provides insight into hyper-virulence of Streptococcus suis LSM178, a human strain with a novel sequence type 1005. PMID:34907269
An Auto-Regulating Type II Toxin-Antitoxin System Modulates Drug Resistance and Virulence in Streptococcus suis. PMID:34475853
Biological Functions of Type II Toxin-Antitoxin Systems in Bacteria. PMID:34208120
Entropic pressure controls the oligomerization of the Vibrio cholerae ParD2 antitoxin. PMID:34196617
Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain. PMID:34121661
Functional Characterization of the mazEF Toxin-Antitoxin System in the Pathogenic Bacterium Agrobacterium tumefaciens. PMID:34065548
Genomics-guided identification of a conserved CptBA-like toxin-antitoxin system in Acinetobacter baumannii. PMID:34026293
Methylation analysis of Klebsiella pneumoniae from Portuguese hospitals. PMID:33753763
The Cysteine Protease MaOC1, a Prokaryotic Caspase Homolog, Cleaves the Antitoxin of a Type II Toxin-Antitoxin System. PMID:33679669
Toxin-antitoxin systems and their medical applications: current status and future perspective. PMID:33582835
Functional and structural characterization of Deinococcus radiodurans R1 MazEF toxin-antitoxin system, Dr0416-Dr0417. PMID:33527318
Targeting Type II Toxin-Antitoxin Systems as Antibacterial Strategies. PMID:32899634
Endosymbionts of Metazoans Dwelling in the PACManus Hydrothermal Vent: Diversity and Potential Adaptive Features Revealed by Genome Analysis. PMID:32859597
Presence of toxin-antitoxin systems in picocyanobacteria and their ecological implications. PMID:32814864
Two Lineages of Pseudomonas aeruginosa Filamentous Phages: Structural Uniformity over Integration Preferences. PMID:32658245
Specialised functions of two common plasmid mediated toxin-antitoxin systems, ccdAB and pemIK, in Enterobacteriaceae. PMID:32603331
A Physiological Basis for Nonheritable Antibiotic Resistance. PMID:32546621
Genomic and Proteomic Characterization of the Extended-Spectrum β-Lactamase (ESBL)-Producing Escherichia coli Strain CCUG 73778: A Virulent, Nosocomial Outbreak Strain. PMID:32545759
Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism. PMID:32382148
Novel Toxin-Antitoxin Module SlvT-SlvA Regulates Megaplasmid Stability and Incites Solvent Tolerance in Pseudomonas putida S12. PMID:32358012
Comparative Genomic Analysis Provides Insights into the Phylogeny, Resistome, Virulome, and Host Adaptation in the Genus Ewingella. PMID:32354059
Toxin-Antitoxin Gene Pairs Found in Tn3 Family Transposons Appear To Be an Integral Part of the Transposition Module. PMID:32234815
Type II and type IV toxin-antitoxin systems show different evolutionary patterns in the global Klebsiella pneumoniae population. PMID:32232417
Genome Insights of the Plant-Growth Promoting Bacterium Cronobacter muytjensii JZ38 With Volatile-Mediated Antagonistic Activity Against Phytophthora infestans. PMID:32218777
Safety Aspects of Genetically Modified Lactic Acid Bacteria. PMID:32098042
Type II Toxin-Antitoxin Systems: Evolution and Revolutions. PMID:31932311
Reassessing the Role of the Type II MqsRA Toxin-Antitoxin System in Stress Response and Biofilm Formation: mqsA Is Transcriptionally Uncoupled from mqsR. PMID:31848281
Piscirickettsia salmonis Cryptic Plasmids: Source of Mobile DNA and Virulence Factors. PMID:31795181
Expression of different ParE toxins results in conserved phenotypes with distinguishable classes of toxicity. PMID:31309747
Toxin-antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA-KacT complex. PMID:31260525
Bioinformatic and mutational studies of related toxin-antitoxin pairs in Mycobacterium tuberculosis predict and identify key functional residues. PMID:31018964
Non-contiguous finished genome sequencing and description of Enterococcus timonensis sp. nov. isolated from human sputum. PMID:31011427
The Wolbachia mobilome in Culex pipiens includes a putative plasmid. PMID:30837458
Large Circular Plasmids from Groundwater Plasmidomes Span Multiple Incompatibility Groups and Are Enriched in Multimetal Resistance Genes. PMID:30808697
Characterization and comparative analysis of toxin-antitoxin systems in Acetobacter pasteurianus. PMID:30805740
In Silico Analysis of Genetic VapC Profiles from the Toxin-Antitoxin Type II VapBC Modules among Pathogenic, Intermediate, and Non-Pathogenic Leptospira. PMID:30791633
Persistence and Microevolution of Pseudomonas aeruginosa in the Cystic Fibrosis Lung: A Single-Patient Longitudinal Genomic Study. PMID:30692969
ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism. PMID:30598453
The XRE-DUF397 Protein Pair, Scr1 and Scr2, Acts as a Strong Positive Regulator of Antibiotic Production in Streptomyces. PMID:30524403
Induction of a Toxin-Antitoxin Gene Cassette under High Hydrostatic Pressure Enables Markerless Gene Disruption in the Hyperthermophilic Archaeon Pyrococcus yayanosii. PMID:30504216
The toxin from a ParDE toxin-antitoxin system found in Pseudomonas aeruginosa offers protection to cells challenged with anti-gyrase antibiotics. PMID:30427086
Genome Structure of the Opportunistic Pathogen Paracoccus yeei (Alphaproteobacteria) and Identification of Putative Virulence Factors. PMID:30410477
Nitrosomonas europaea MazF Specifically Recognises the UGG Motif and Promotes Selective RNA Degradation. PMID:30349517
A genetically engineered Escherichia coli that senses and degrades tetracycline antibiotic residue. PMID:30345405
Antibiotics, Resistome and Resistance Mechanisms: A Bacterial Perspective. PMID:30298054
SLING: a tool to search for linked genes in bacterial datasets. PMID:30124998
Functional insights into the Streptococcus pneumoniae HicBA toxin-antitoxin system based on a structural study. PMID:29878152
A Comparative Genomic Analysis Provides Novel Insights Into the Ecological Success of the Monophasic Salmonella Serovar 4,[5],12:i: PMID:29719530
A Toxin-Antitoxin System VapBC15 from Synechocystis sp. PCC 6803 Shows Distinct Regulatory Features. PMID:29561797
Autoregulation and Virulence Control by the Toxin-Antitoxin System SavRS in Staphylococcus aureus. PMID:29440365
Identification of a functional toxin-antitoxin system located in the genomic island PYG1 of piezophilic hyperthermophilic archaeon Pyrococcus yayanosii. PMID:29335804
The Role for the Small Cryptic Plasmids As Moldable Vectors for Genetic Innovation in Aeromonas salmonicida subsp. salmonicida. PMID:29326751
Strong Genomic and Phenotypic Heterogeneity in the Aeromonas sobria Species Complex. PMID:29276504
Epidemiology of Danish Aeromonas salmonicida subsp. salmonicida in Fish Farms Using Whole Genome Sequencing. PMID:29259599
First insights into a type II toxin-antitoxin system from the clinical isolate Mycobacterium sp. MHSD3, similar to epsilon/zeta systems. PMID:29236773
Complete Genome Sequence Analysis of Enterobacter sp. SA187, a Plant Multi-Stress Tolerance Promoting Endophytic Bacterium. PMID:29163376
TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci. PMID:29106666
Fic Proteins of Campylobacter fetus subsp. venerealis Form a Network of Functional Toxin-Antitoxin Systems. PMID:29089929
Archaeal Persisters: Persister Cell Formation as a Stress Response in Haloferax volcanii. PMID:28871247
Deinococcus radiodurans Toxin-Antitoxin MazEF-dr Mediates Cell Death in Response to DNA Damage Stress. PMID:28798741
Toxin-Antitoxin Systems in Estuarine Synechococcus Strain CB0101 and Their Transcriptomic Responses to Environmental Stressors. PMID:28729858
Diversity, Prevalence, and Longitudinal Occurrence of Type II Toxin-Antitoxin Systems of Pseudomonas aeruginosa Infecting Cystic Fibrosis Lungs. PMID:28690609
Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides. PMID:28575388
Structural conservation of the PIN domain active site across all domains of life. PMID:28508407
Tripartite species interaction: eukaryotic hosts suffer more from phage susceptible than from phage resistant bacteria. PMID:28399796
Complete genome sequencing and antibiotics biosynthesis pathways analysis of Streptomyces lydicus 103. PMID:28317865
Plasmid interference for curing antibiotic resistance plasmids in vivo. PMID:28245276
The Influence of the Toxin/Antitoxin mazEF on Growth and Survival of Listeria monocytogenes under Stress. PMID:28098783
Functional Studies of Five Toxin-Antitoxin Modules in Mycobacterium tuberculosis H37Rv. PMID:28066388
Networking in microbes: conjugative elements and plasmids in the genus Alteromonas. PMID:28056800
What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and Persistence? PMID:27933045
Transcriptional Profiling of Type II Toxin-Antitoxin Genes of Helicobacter pylori under Different Environmental Conditions: Identification of HP0967-HP0968 System. PMID:27920769
Identification of a VapBC toxin-antitoxin system in a thermophilic bacterium Thermus thermophilus HB27. PMID:27853887
The Genome of the Toluene-Degrading Pseudomonas veronii Strain 1YdBTEX2 and Its Differential Gene Expression in Contaminated Sand. PMID:27812150
Structure, Biology, and Therapeutic Application of Toxin-Antitoxin Systems in Pathogenic Bacteria. PMID:27782085
Genomic analyses of multidrug resistant Pseudomonas aeruginosa PA1 resequenced by single-molecule real-time sequencing. PMID:27765811
Diversity of antibiotic-resistance genes in Canadian isolates of Aeromonas salmonicida subsp. salmonicida: dominance of pSN254b and discovery of pAsa8. PMID:27752114
Draft genome sequence of Acinetobacter baumannii strain NCTC 13423, a multidrug-resistant clinical isolate. PMID:27594976
Identification and characterization of chromosomal relBE toxin-antitoxin locus in Streptomyces cattleya DSM46488. PMID:27534445
Type II Toxin-Antitoxin Systems in the Unicellular Cyanobacterium Synechocystis sp. PCC 6803. PMID:27455323
Mapping Protein-Protein Interactions of the Resistance-Related Bacterial Zeta Toxin-Epsilon Antitoxin Complex (ε₂ζ₂) with High Affinity Peptide Ligands Using Fluorescence Polarization. PMID:27438853
Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways. PMID:27409636
Persister formation in Staphylococcus aureus is associated with ATP depletion. PMID:27398229
Characterization of the Deep-Sea Streptomyces sp. SCSIO 02999 Derived VapC/VapB Toxin-Antitoxin System in Escherichia coli. PMID:27376329
Desperate times call for desperate measures: benefits and costs of toxin-antitoxin systems. PMID:27276988
AAU-Specific RNA Cleavage Mediated by MazF Toxin Endoribonuclease Conserved in Nitrosomonas europaea. PMID:27271670
A Salmonella Toxin Promotes Persister Formation through Acetylation of tRNA. PMID:27264868
Type II Toxin-Antitoxin Distribution and Adaptive Aspects on Xanthomonas Genomes: Focus on Xanthomonas citri. PMID:27242687
High Persister Mutants in Mycobacterium tuberculosis. PMID:27176494
Toxin-Antitoxin Systems of Staphylococcus aureus. PMID:27164142
Keeping the Wolves at Bay: Antitoxins of Prokaryotic Type II Toxin-Antitoxin Systems. PMID:27047942
Characterization of MazF-Mediated Sequence-Specific RNA Cleavage in Pseudomonas putida Using Massive Parallel Sequencing. PMID:26885644
A Site-Specific Integrative Plasmid Found in Pseudomonas aeruginosa Clinical Isolate HS87 along with A Plasmid Carrying an Aminoglycoside-Resistant Gene. PMID:26841043
Major bacterial lineages are essentially devoid of CRISPR-Cas viral defence systems. PMID:26837824
Stability of the GraA Antitoxin Depends on Growth Phase, ATP Level, and Global Regulator MexT. PMID:26668267
Diversity and Homogeneity among Small Plasmids of Aeromonas salmonicida subsp. salmonicida Linked with Geographical Origin. PMID:26635745
Physiologic Stresses Reveal a Salmonella Persister State and TA Family Toxins Modulate Tolerance to These Stresses. PMID:26633172
Type II toxin: antitoxin systems. More than small selfish entities? PMID:26597447
Dynamics of Wolbachia pipientis Gene Expression Across the Drosophila melanogaster Life Cycle. PMID:26497146
Viable but Nonculturable and Persister Cells Coexist Stochastically and Are Induced by Human Serum. PMID:26283335
A Type III protein-RNA toxin-antitoxin system from Bacillus thuringiensis promotes plasmid retention during spore development. PMID:26274022
Comprehensive Functional Analysis of the 18 Vibrio cholerae N16961 Toxin-Antitoxin Systems Substantiates Their Role in Stabilizing the Superintegron. PMID:25897030
The dnd operon for DNA phosphorothioation modification system in Escherichia coli is located in diverse genomic islands. PMID:25879448
Antibiotic-free selection in biotherapeutics: now and forever. PMID:25854922
A set of powerful negative selection systems for unmodified Enterobacteriaceae. PMID:25800749
Distinct type I and type II toxin-antitoxin modules control Salmonella lifestyle inside eukaryotic cells. PMID:25792384
Comparative genomic analysis of Mycobacterium iranicum UM_TJL against representative mycobacterial species suggests its environmental origin. PMID:25417557
Toxin-antitoxin systems in the mobile genome of Acidithiobacillus ferrooxidans. PMID:25384039
The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. PMID:25056321
VapC from the leptospiral VapBC toxin-antitoxin module displays ribonuclease activity on the initiator tRNA. PMID:25047537
Crystal structure of toxin HP0892 from Helicobacter pylori with two Zn(II) at 1.8 Å resolution. PMID:24677509
Internalization of Salmonella by macrophages induces formation of nonreplicating persisters. PMID:24408438
To be or not to be: regulation of restriction-modification systems and other toxin-antitoxin systems. PMID:23945938
Identification and characterization of type II toxin-antitoxin systems in the opportunistic pathogen Acinetobacter baumannii. PMID:23667234
Stable expression plasmids for Streptomyces based on a toxin-antitoxin system. PMID:23617558
Mobile elements in a single-filament orange Guaymas Basin Beggiatoa ("Candidatus Maribeggiatoa") sp. draft genome: evidence for genetic exchange with cyanobacteria. PMID:23603674
Discovery of functional toxin/antitoxin systems in bacteria by shotgun cloning. PMID:23478446
Transcriptional cross-activation between toxin-antitoxin systems of Escherichia coli. PMID:23432955
Cryptic Streptococcus mutans 5.6-kb plasmids encode a toxin-antitoxin system for plasmid stabilization. PMID:23330057
Characterization of a Streptococcus mutans intergenic region containing a small toxic peptide and its cis-encoded antisense small RNA antitoxin. PMID:23326602
Toxin-antitoxin systems on the large defense plasmid pSYSA of Synechocystis sp. PCC 6803. PMID:23322786
Identification of chromosomal HP0892-HP0893 toxin-antitoxin proteins in Helicobacter pylori and structural elucidation of their protein-protein interaction. PMID:23297406
Toxin-antitoxin genes of the Gram-positive pathogen Streptococcus pneumoniae: so few and yet so many. PMID:23204366
Characterization of a mazEF toxin-antitoxin homologue from Staphylococcus equorum. PMID:23104807
Comparative genomics evidence that only protein toxins are tagging bad bugs. PMID:22919573
Crystallization and preliminary crystallographic studies of the YafN-YafO complex from Escherichia coli. PMID:22869116
Artificial activation of toxin-antitoxin systems as an antibacterial strategy. PMID:22445361
Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes. PMID:22434880
Identification of the first functional toxin-antitoxin system in Streptomyces. PMID:22431991
A vast collection of microbial genes that are toxic to bacteria. PMID:22300632
Regulation of enteric vapBC transcription: induction by VapC toxin dimer-breaking. PMID:22287572
ICEberg: a web-based resource for integrative and conjugative elements found in Bacteria. PMID:22009673
Regulation of growth and death in Escherichia coli by toxin-antitoxin systems. PMID:21927020
Genetic regulation of the yefM-yoeB toxin-antitoxin locus of Streptococcus pneumoniae. PMID:21764929
Bacillus subtilis MazF-bs (EndoA) is a UACAU-specific mRNA interferase. PMID:21763692
Genomes of the most dangerous epidemic bacteria have a virulence repertoire characterized by fewer genes but more toxin-antitoxin modules. PMID:21437250
http://dx.doi.org/10.1093/nar/gkq908

Tags:

Tags
More detailed information about this field from each metasource.

genomics databases (non-vertebrate)
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

prokaryotic genome databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

small molecules
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:55.397797

phylogenetics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:55.397797

mapping
metasource: bio.tools
version: extracted_at: 2022-11-04T11:33:55.397797

genomics prokaryotic genome small molecule phylogenetics mapping

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