REporting recommendations for tumour MARKer prognostic studies
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REporting recommendations for tumour MARKer prognostic studies
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
REMARK
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
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More detailed information about this field from each metasource.
REporting recommendations for tumour MARKer prognostic studies
metasource: Fairsharing.orgversion: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
REMARK
metasource: Fairsharing.orgversion: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Names
More detailed information about this field from each metasource.
REporting recommendations for tumour MARKer prognostic studies
metasource: Fairsharing.orgversion: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
REMARK
metasource: Fairsharing.orgversion: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
As for the successful CONSORT initiative for randomized trials and for the STARD statement for diagnostic studies, we suggest guidelines to provide relevant information about the study design, preplanned hypotheses, patient and specimen characteristics, assay methods, and statistical analysis methods. In addition, the guidelines provide helpful suggestions on how to present data and important elements to include in discussions.
Description
More detailed information about this field from each metasource.
As for the successful CONSORT initiative for randomized trials and for the STARD statement for diagnostic studies, we suggest guidelines to provide relevant information about the study design, preplanned hypotheses, patient and specimen characteristics, assay methods, and statistical analysis methods. In addition, the guidelines provide helpful suggestions on how to present data and important elements to include in discussions.
metasource: Fairsharing.orgversion: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Webpage:
http://www.equator-network.org/reporting-guidelines/reporting-recommendations-for-tumour-marker-prognostic-studies-remark/Webpage
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http://www.equator-network.org/reporting-guidelines/reporting-recommendations-for-tumour-marker-prognostic-studies-remark/
metasource: Fairsharing.orgversion: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Publications:
Publications
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REporting recommendations for tumour MARKer prognostic studies (REMARK)
PMID: 16106245
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration
PMID: 22675273
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration
PMID: 22642691
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Publications
More detailed information about this field from each metasource.
REporting recommendations for tumour MARKer prognostic studies (REMARK)
PMID: 16106245
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration
PMID: 22675273
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration
PMID: 22642691
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
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REporting recommendations for tumour MARKer prognostic studies (REMARK)
PubMed citations: 481.
481 articles citing: REporting recommendations for tumour MARKer prognostic studies (REMARK)
A Systematic Review to Define the Multi-Faceted Role of Lysine Methyltransferase SETD7 in Cancer. PMID:35326563
Upregulation of Cyclin B2 (CCNB2) in breast cancer contributes to the development of lymphovascular invasion. PMID:35261781
Ligand-mediated PAI-1 inhibition in a mouse model of peritoneal carcinomatosis. PMID:35243423
Usefulness of Short-Term Imaging and Squamous Cell Carcinoma Antigen to Early Predict Response to Concurrent Chemoradiotherapy in Patients With Cervical Cancer. PMID:35196888
Extravesicular TIMP-1 is a non-invasive independent prognostic marker and potential therapeutic target in colorectal liver metastases. PMID:35140332
Decreased expression of farnesoid X receptor may indicate poor prognosis in patients with colorectal cancer. PMID:35117795
The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer. PMID:35078526
A three-phase trans-ethnic study reveals B7-H3 expression is a significant and independent biomarker associated with colon cancer overall survival. PMID:35070416
Racial differences in breast cancer outcomes by hepatocyte growth factor pathway expression. PMID:35034243
An exploration of immunohistochemistry-based prognostic markers in patients undergoing curative resections for colon cancer. PMID:35027037
Circulating Tumor Cell Transcriptomics as Biopsy Surrogates in Metastatic Breast Cancer. PMID:35000083
SPTAN1, APC, and FGFR3 Mutation Status and APOBEC Mutation Signatures are Predictive of Mitomycin C Response in Non-muscle-invasive Bladder Cancer. PMID:34934968
AGAP2-AS1 as a prognostic biomarker in low-risk clear cell renal cell carcinoma patients with progressing disease. PMID:34930263
The BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents. PMID:34903710
High Moesin Expression Is a Predictor of Poor Prognosis of Breast Cancer: Evidence From a Systematic Review With Meta-Analysis. PMID:34900662
Tumor Mutational Burden as a Biomarker for Advanced Biliary Tract Cancer. PMID:34855561
hENT1 Predicts Benefit from Gemcitabine in Pancreatic Cancer but Only with Low CDA mRNA. PMID:34830914
Pretreatment neutrophil-to-lymphocyte ratio as an important prognostic marker in stage III locally advanced non-small cell lung cancer: confirmatory results from the PROCLAIM phase III clinical trial. PMID:34795912
C-Reactive Protein and C-Reactive Protein-Based Scores to Predict Survival in Esophageal and Junctional Adenocarcinoma: Systematic Review and Meta-Analysis. PMID:34773194
Association Between Estrogen Receptors and GATA3 in Bladder Cancer: A Systematic Review and Meta-Analysis of Their Clinicopathological Significance. PMID:34690921
Serum miR-373-3p and miR-194-5p Are Associated with Early Tumor Progression during FOLFIRINOX Treatment in Pancreatic Cancer Patients: A Prospective Multicenter Study. PMID:34681562
The Soluble Urokinase-Type Plasminogen Activator Receptor as a Biomarker for Survival and Early Treatment Effect in Metastatic Colorectal Cancer. PMID:34680247
The prognostic value of intratumoral and peritumoral tumor-infiltrating FoxP3+Treg cells in of pancreatic adenocarcinoma: a meta-analysis. PMID:34654443
Increased coexpression of PD-L1 and TIM3/TIGIT is associated with poor overall survival of patients with esophageal squamous cell carcinoma. PMID:34625514
An analysis of the immunological tumor microenvironment of primary tumors and regional lymph nodes in squamous cell lung cancer. PMID:34584854
High CYP27A1 expression is a biomarker of favorable prognosis in premenopausal patients with estrogen receptor positive primary breast cancer. PMID:34556659
A 14-Marker Multiplexed Imaging Panel for Prognostic Biomarkers and Tumor Heterogeneity in Head and Neck Squamous Cell Carcinoma. PMID:34490110
Oestrogen-regulated protein SLC39A6: a biomarker of good prognosis in luminal breast cancer. PMID:34453638
Overexpression of miR-20a-5p in Tumor Epithelium Is an Independent Negative Prognostic Indicator in Prostate Cancer-A Multi-Institutional Study. PMID:34439249
Circulating TP53 mutations are associated with early tumor progression and poor survival in pancreatic cancer patients treated with FOLFIRINOX. PMID:34422118
Prognostic and Predictive Value of HER2 Expression in Ductal Carcinoma In Situ: Results from the UK/ANZ DCIS Randomized Trial. PMID:34380636
Expression of HLA-DR in Cytotoxic T Lymphocytes: A Validated Predictive Biomarker and a Potential Therapeutic Strategy in Breast Cancer. PMID:34359741
The prognostic utility of pre-treatment neutrophil-to-lymphocyte-ratio (NLR) in colorectal cancer: A systematic review and meta-analysis. PMID:34308567
Preoperative iron status is a prognosis factor for stage II and III colorectal cancer. PMID:34302234
High expression of miR-17-5p in tumor epithelium is a predictor for poor prognosis for prostate cancer patients. PMID:34226620
Homologous Recombination Deficiency in Pancreatic Cancer: A Systematic Review and Prevalence Meta-Analysis. PMID:34197182
Blood-Based Biomarkers for Glioma in the Context of Gliomagenesis: A Systematic Review. PMID:34150629
Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer. PMID:34108626
Expression of Immune Checkpoint Regulators IDO, VISTA, LAG3, and TIM3 in Resected Pancreatic Ductal Adenocarcinoma. PMID:34072549
Analysis of Increased EGFR and IGF-1R Signaling and Its Correlation with Socio-Epidemiological Features and Biological Profile in Breast Cancer Patients: A Study in Northern Brazil. PMID:34054308
HPV ctDNA detection of high-risk HPV types during chemoradiotherapy for locally advanced cervical cancer. PMID:34022731
PP1, PKA and DARPP-32 in breast cancer: A retrospective assessment of protein and mRNA expression. PMID:33991172
Quality Considerations When Using Tissue Samples for Biomarker Studies in Cancer Research. PMID:33958852
Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2). PMID:33941784
Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study. PMID:33939694
Biomarkers in Prostate Cancer Diagnosis: From Current Knowledge to the Role of Metabolomics and Exosomes. PMID:33922033
Expression of CCL2/CCR2 signaling proteins in breast carcinoma cells is associated with invasive progression. PMID:33888841
Magnetic resonance biomarkers in radiation oncology: The report of AAPM Task Group 294. PMID:33864283
Preoperative transferrin level is a novel prognostic marker for colorectal cancer. PMID:33860145
High KDM1A Expression Associated with Decreased CD8+T Cells Reduces the Breast Cancer Survival Rate in Patients with Breast Cancer. PMID:33799951
Low RAI2 expression is a marker of poor prognosis in breast cancer. PMID:33782811
IP6K2 predicts favorable clinical outcome of primary breast cancer. PMID:33767863
The density of tumor-infiltrating lymphocytes and prognosis in resectable hepatocellular carcinoma: a two-phase study. PMID:33744864
The lung immuno-oncology prognostic score (LIPS-3): a prognostic classification of patients receiving first-line pembrolizumab for PD-L1 ≥ 50% advanced non-small-cell lung cancer. PMID:33735802
Prognostic Value of ER and PgR Expression and the Impact of Multi-clonal Expression for Recurrence in Ductal Carcinoma in situ: Results from the UK/ANZ DCIS Trial. PMID:33727261
MMP7 as a potential biomarker of colon cancer and its prognostic value by bioinformatics analysis. PMID:33655961
Characterising cancer-associated fibroblast heterogeneity in non-small cell lung cancer: a systematic review and meta-analysis. PMID:33580106
Statistical Considerations in the Evaluation of Continuous Biomarkers. PMID:33579807
Prognostic significance of the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio for advanced non-small cell lung cancer patients with high PD-L1 tumor expression receiving pembrolizumab. PMID:33569318
Identification of potential salivary biomarker panels for oral squamous cell carcinoma. PMID:33564003
Combined analysis of miR-200 family and its significance for breast cancer. PMID:33536459
Effects of systemic inflammation on relapse in early breast cancer. PMID:33483516
Immune cell infiltrates as prognostic biomarkers in pancreatic ductal adenocarcinoma: a systematic review and meta-analysis. PMID:33481339
Prognostic role of TSPAN1, KIAA1324 and ESRP1 in prostate cancer. PMID:33455017
A template to quantify the location and density of CD3 + and CD8 + tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for an objective, standardized immune score assessment. PMID:33439293
Increased risk of brain metastases among patients with melanoma and PROM2 expression in metastatic lymph nodes. PMID:33377645
The prognostic value of CD3+ tumor-infiltrating lymphocytes for stage II colon cancer according to use of adjuvant chemotherapy: A large single-institution cohort study. PMID:33338878
Prognostic significance of the preoperative systemic immune-inflammation index in patients with oral cavity squamous cell carcinoma treated with curative surgery and adjuvant therapy. PMID:33325655
Hypertriglyceridemia in Newly Diagnosed Acute Promyelocytic Leukemia. PMID:33324553
Prospective validation of microseminoprotein-β added to the 4Kscore in predicting high-grade prostate cancer in an international multicentre cohort. PMID:33306251
Three tumor markers for improved efficacy in the management of patients with malignant pleural mesothelioma. PMID:33282372
SITC cancer immunotherapy resource document: a compass in the land of biomarker discovery. PMID:33268350
miR-10a as a therapeutic target and predictive biomarker for MDM2 inhibition in acute myeloid leukemia. PMID:33262524
The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer. PMID:33223535
Circulating tumor DNA as a potential prognostic and predictive biomarker during interventional therapy of unresectable primary liver cancer. PMID:33209498
Using Machine Learning Algorithms to Predict Immunotherapy Response in Patients with Advanced Melanoma. PMID:33208341
A Pilot Study Comparing the Efficacy of Lactate Dehydrogenase Levels Versus Circulating Cell-Free microRNAs in Monitoring Responses to Checkpoint Inhibitor Immunotherapy in Metastatic Melanoma Patients. PMID:33202891
CEA and CYFRA 21-1 as prognostic biomarker and as a tool for treatment monitoring in advanced NSCLC treated with immune checkpoint inhibitors. PMID:33193825
Nucleolar protein 10 (NOP10) predicts poor prognosis in invasive breast cancer. PMID:33161513
Circulating Tumour Cell Expression of Immune Markers as Prognostic and Therapeutic Biomarkers in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. PMID:33153130
A non-linear optimisation method to extract summary statistics from Kaplan-Meier survival plots using the published P value. PMID:33126853
Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis. PMID:33101778
Circulating biomarkers and outcomes from a randomised phase 2 trial of gemcitabine versus capecitabine-based chemoradiotherapy for pancreatic cancer. PMID:33100327
Evidence for different molecular parameters in head and neck squamous cell carcinoma of nonsmokers and nondrinkers: Systematic review and meta-analysis on HPV, p16, and TP53. PMID:33098216
The Prognostic Value of Toll-Like Receptors in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. PMID:33008143
Optimization of an automated tumor-infiltrating lymphocyte algorithm for improved prognostication in primary melanoma. PMID:33005020
Role of LATS1/2 in Prognosis of Advanced Gastric Cancer and Its Relationship With the Tumor Immune Microenvironment. PMID:32983971
KLK3 and TMPRSS2 for molecular lymph-node staging in prostate cancer patients undergoing radical prostatectomy. PMID:32978525
Neutrophil-to-lymphocyte ratio in combination with PD-L1 or lactate dehydrogenase as biomarkers for high PD-L1 non-small cell lung cancer treated with first-line pembrolizumab. PMID:32953525
Prognostic and predictive significance of nuclear HIF1α expression in locally advanced HNSCC patients treated with chemoradiation with or without nimotuzumab. PMID:32939054
Systemic inflammation is associated with circulating cell death released keratin 18 fragments in colorectal cancer. PMID:32923147
Hsa-miR-155-5p Up-Regulation in Breast Cancer and Its Relevance for Treatment With Poly[ADP-Ribose] Polymerase 1 (PARP-1) Inhibitors. PMID:32903519
The nucleolar-related protein Dyskerin pseudouridine synthase 1 (DKC1) predicts poor prognosis in breast cancer. PMID:32868896
A Systematic Approach to Review of in vitro Methods in Brain Tumour Research (SAToRI-BTR): Development of a Preliminary Checklist for Evaluating Quality and Human Relevance. PMID:32850761
Lack of Androgen Receptor Expression Selects for Basal-Like Phenotype and Is a Predictor of Poor Clinical Outcome in Non-Metastatic Triple Negative Breast Cancer. PMID:32850312
Downstream neighbor of SON (DONSON) is associated with unfavorable survival across diverse cancers with oncogenic properties in clear cell renal cell carcinoma. PMID:32805676
FOXP3+ Tregs exhibit different infiltrating status and predict a distinct prognosis in primary lesions and hepatic metastases in stage III&IV advanced gastric cancer. PMID:32774723
Immune system and angiogenesis-related potential surrogate biomarkers of response to everolimus-based treatment in hormone receptor-positive breast cancer: an exploratory study. PMID:32770287
Elevated serum YKL-40, IL-6, CRP, CEA, and CA19-9 combined as a prognostic biomarker panel after resection of colorectal liver metastases. PMID:32756596
Prognostic Gene Expression Profiling in Cutaneous Melanoma: Identifying the Knowledge Gaps and Assessing the Clinical Benefit. PMID:32725204
Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer. PMID:32676968
Farnesoid X receptor as marker of osteotropism of breast cancers through its role in the osteomimetism of tumor cells. PMID:32650752
Integrated Assessment of Circulating Cell-Free MicroRNA Signatures in Plasma of Patients with Melanoma Brain Metastasis. PMID:32630542
Dopamine and cAMP-regulated phosphoprotein 32kDa (DARPP-32), protein phosphatase-1 and cyclin-dependent kinase 5 expression in ovarian cancer. PMID:32588513
Prognostic Biomarkers in Endometrial Cancer: A Systematic Review and Meta-Analysis. PMID:32560580
The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation. PMID:32487090
Clinical utility of tumour marker velocity of cancer antigen 15-3 (CA 15-3) and carcinoembryonic antigen (CEA) in breast cancer surveillance. PMID:32485607
Prognostic value of lymph node ratio in laryngeal and hypopharyngeal squamous cell carcinoma: a systematic review and meta-analysis. PMID:32471483
Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival. PMID:32445177
Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival. PMID:32434859
High polymerase ε expression associated with increased CD8+T cells improves survival in patients with non-small cell lung cancer. PMID:32433714
Thioredoxin System Protein Expression Is Associated with Poor Clinical Outcome in Adult and Paediatric Gliomas and Medulloblastomas. PMID:32418115
A novel prognostic two-gene signature for triple negative breast cancer. PMID:32404959
Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. PMID:32401426
Association between serum biomarkers CEA and LDH and response in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy. PMID:32383328
Retrospective assessment of cyclin-dependent kinase 5 mRNA and protein expression and its association with patient survival in breast cancer. PMID:32352232
Prevalence of PD-L1 expression is associated with EMAST, density of peritumoral T-cells and recurrence-free survival in operable non-metastatic colorectal cancer. PMID:32314040
Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer. PMID:32296755
Prognostic impact of ACTN4 gene copy number alteration in hormone receptor-positive, HER2-negative, node-negative invasive breast carcinoma. PMID:32265507
Biological tumor markers associated with local control after primary radiotherapy in laryngeal cancer: A systematic review. PMID:32246586
Mitotic score and pleomorphic histology in invasive lobular carcinoma of the breast: impact on disease-free survival. PMID:32240457
Immunohistochemical validation study of 15-gene biomarker panel predictive of benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of JBR.10. PMID:32220948
The solute carrier SLC7A8 is a marker of favourable prognosis in ER-positive low proliferative invasive breast cancer. PMID:32200487
Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC. PMID:32183347
TP53 Mutations in Serum Circulating Cell-Free Tumor DNA As Longitudinal Biomarker for High-Grade Serous Ovarian Cancer. PMID:32156073
Circulating Epstein-Barr virus microRNAs BART7-3p and BART13-3p as novel biomarkers in nasopharyngeal carcinoma. PMID:32155300
Clinical relevance of circulating tumor cells in ovarian, fallopian tube and peritoneal cancer. PMID:32144573
Baseline Plasma Tumor Mutation Burden Predicts Response to Pembrolizumab-based Therapy in Patients with Metastatic Non-Small Cell Lung Cancer. PMID:32102950
Vasculogenic Mimicry: A Promising Prognosticator in Head and Neck Squamous Cell Carcinoma and Esophageal Cancer? A Systematic Review and Meta-Analysis. PMID:32102317
The Prognostic Implications of Tumor Infiltrating Lymphocytes in Colorectal Cancer: A Systematic Review and Meta-Analysis. PMID:32099066
YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling. PMID:32054505
A 4-gene signature from histologically normal surgical margins predicts local recurrence in patients with oral carcinoma: clinical validation. PMID:32015424
Tumour budding in preoperative biopsy specimens is a useful prognostic index for identifying high-risk patients in early-stage (pN0) colon cancer. PMID:32011836
Prognostic DNA methylation markers for hormone receptor breast cancer: a systematic review. PMID:32005275
Interim PET-results for prognosis in adults with Hodgkin lymphoma: a systematic review and meta-analysis of prognostic factor studies. PMID:31930780
Overexpression of Annexin A1 Is an Independent Predictor of Longer Overall Survival in Epithelial Ovarian Cancer. PMID:31882477
Prognostic significance of serum p53 antibody according to KRAS status in metastatic colorectal cancer patients. PMID:31834556
Immunohistochemical expression of TFIIH and XPF in oral tongue squamous cell carcinoma. PMID:31828418
Prognostic value of mitotic checkpoint protein BUB3, cyclin B1, and pituitary tumor-transforming 1 expression in prostate cancer. PMID:31801961
How pathological criteria can impact prognosis of tongue and floor of the mouth squamous cell carcinoma. PMID:31800876
Expression and potential prognostic value of histone family gene signature in breast cancer. PMID:31772649
Relationship between the immune microenvironment of different locations in a primary tumour and clinical outcomes of oesophageal squamous cell carcinoma. PMID:31761900
Tumor Infiltrating Lymphocytes and CD8+ T Cell Subsets as Prognostic Markers in Patients with Surgically Treated Laryngeal Squamous Cell Carcinoma. PMID:31749124
Targeting the TIGIT-PVR immune checkpoint axis as novel therapeutic option in breast cancer. PMID:31741778
Dopamine and cAMP-regulated phosphoprotein 32 kDa (DARPP-32) and survival in breast cancer: a retrospective analysis of protein and mRNA expression. PMID:31740718
Androgen receptor expression and response to chemotherapy in breast cancer patients treated in the neoadjuvant TECHNO and PREPARE trial. PMID:31728025
Prognostic value and clinicopathological roles of phenotypes of tumour-associated macrophages in colorectal cancer. PMID:31650222
PDL1 expression is associated with longer postoperative, survival in adrenocortical carcinoma. PMID:31646101
Systematic review and REMARK scoring of renal cell carcinoma prognostic circulating biomarker manuscripts. PMID:31639128
Performance of DNA methylation assays for detection of high-grade cervical intraepithelial neoplasia (CIN2+): a systematic review and meta-analysis. PMID:31616037
A study protocol for the development and internal validation of a multivariable prognostic model to determine lower extremity muscle injury risk in elite football (soccer) players, with further exploration of prognostic factors. PMID:31548994
Interim PET-results for prognosis in adults with Hodgkin lymphoma: a systematic review and meta-analysis of prognostic factor studies. PMID:31525824
Prognostic value of blood and lymphatic vessel markers in tongue cancer: A systematic review. PMID:31495050
Circulating tumour cells and hypercoagulability: a lethal relationship in metastatic breast cancer. PMID:31473984
The impact of neutrophil-lymphocyte ratio on risk reclassification of patients with advanced renal cell cancer to guide risk-directed therapy. PMID:31462137
Prognostic relevance of DNA damage and repair biomarkers in elderly patients with hormone-receptor-positive breast cancer treated with neoadjuvant hormone therapy: evidence from the real-world setting. PMID:31452691
The utility of Ki-67 as a prognostic biomarker in pulmonary neuroendocrine tumours: protocol for a systematic review and meta-analysis. PMID:31446421
Clinical Relevance of Collagen Protein Degradation Markers C3M and C4M in the Serum of Breast Cancer Patients Treated with Neoadjuvant Therapy in the GeparQuinto Trial. PMID:31443252
PD-L1 expression, CD8+ and CD4+ lymphocyte rate are predictive of pathological complete response after neoadjuvant chemoradiotherapy for squamous cell cancer of the thoracic esophagus. PMID:31429521
Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage. PMID:31388185
Global Consultation on Cancer Staging: promoting consistent understanding and use. PMID:31388125
Low Expression of miR-424-3p is Highly Correlated with Clinical Failure in Prostate Cancer. PMID:31337863
Combination Treatment with an Antibody-Drug Conjugate (A1mcMMAF) Targeting the Oncofetal Glycoprotein 5T4 and Carboplatin Improves Survival in a Xenograft Model of Ovarian Cancer. PMID:31332693
Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases. PMID:31332191
LncRNA SLCO4A1-AS1 promotes colorectal cancer cell proliferation by enhancing autophagy via miR-508-3p/PARD3 axis. PMID:31308265
The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy. PMID:31259422
Reporting quality of the 2014 Ebola outbreak in Africa: A systematic analysis. PMID:31237909
Prognostic significance of cyclin D3 expression in malignancy patients: a meta-analysis. PMID:31198407
Platelet count, aspirin use, and characteristics of host inflammatory responses in colorectal cancer. PMID:31196200
Regulatory T cells and M2 macrophages present diverse prognostic value in gastric cancer patients with different clinicopathologic characteristics and chemotherapy strategies. PMID:31174544
Where is the limit of prostate cancer biomarker research? Systematic investigation of potential prognostic and diagnostic biomarkers. PMID:31170942
High EMSY expression defines a BRCA-like subgroup of high-grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum. PMID:31154673
PARP1 expression in soft tissue sarcomas is a poor-prognosis factor and a new potential therapeutic target. PMID:31131495
The prognostic value of tumor-infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: a systematic review and meta-analysis. PMID:31118034
Correlation Between Natural Killer Cell Activity and Treatment Effect in Patients with Disseminated Cancer. PMID:31103777
The expression of the immune checkpoint regulator VISTA correlates with improved overall survival in pT1/2 tumor stages in esophageal adenocarcinoma. PMID:31069143
Epidermal autophagy and beclin 1 regulator 1 and loricrin: a paradigm shift in the prognostication and stratification of the American Joint Committee on Cancer stage I melanomas. PMID:31056744
XPO1 Expression Is a Poor-Prognosis Marker in Pancreatic Adenocarcinoma. PMID:31052304
Uniformity in measuring adherence to reporting guidelines: the example of TRIPOD for assessing completeness of reporting of prediction model studies. PMID:31023756
Prognostic value of circulating tumour cells in limited-stage small-cell lung cancer: analysis of the concurrent once-daily versus twice-daily radiotherapy (CONVERT) randomised controlled trial. PMID:31020334
A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study. PMID:31015209
Quantitative proteomics identifies brain acid soluble protein 1 (BASP1) as a prognostic biomarker candidate in pancreatic cancer tissue. PMID:30982764
ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer. PMID:30971775
Head and Body/Tail Pancreatic Carcinomas Are Not the Same Tumors. PMID:30965637
NUP98 - a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer. PMID:30935371
Validation of Neutrophil Count as An Algorithm-Based Predictive Factor of Progression-Free Survival in Patients with Metastatic Soft Tissue Sarcomas Treated with Trabectedin. PMID:30917620
Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach. PMID:30890775
MRE11 as a Predictive Biomarker of Outcome After Radiation Therapy in Bladder Cancer. PMID:30885775
Circulating miRNAs as a marker of metastatic disease and prognostic factor in metastatic breast cancer. PMID:30847025
Immune cell score in pancreatic cancer-comparison of hotspot and whole-section techniques. PMID:30843106
A Tool to Encourage Minimum Reporting Guideline Uptake for Data Analysis in Metabolomics. PMID:30841575
Critical review of reporting of the data analysis step in metabolomics. PMID:30830321
Tissue-infiltrating immune cells as prognostic markers in oral squamous cell carcinoma: a systematic review and meta-analysis. PMID:30808992
The prognostic relevance of urokinase-type plasminogen activator (uPA) in the blood of patients with metastatic breast cancer. PMID:30783124
Programmed Death Ligand-1 expression in stage II colon cancer - experiences from a nationwide populationbased cohort. PMID:30755167
Expression of Syk and MAP4 proteins in ovarian cancer. PMID:30737623
Stromal fibronectin expression in patients with resected pancreatic ductal adenocarcinoma. PMID:30736807
Prediction Model for Nodal Disease Among Patients With Non-Small Cell Lung Cancer. PMID:30710518
Epigenomic promoter alterations predict for benefit from immune checkpoint inhibition in metastatic gastric cancer. PMID:30624548
Pre-diagnostic sex hormone levels and survival among breast cancer patients. PMID:30604001
Immunohistochemical investigation of prognostic biomarkers in resected colorectal liver metastases: a systematic review and meta-analysis. PMID:30602942
Alterations in serum amino-acid profile in the progression of colorectal cancer: associations with systemic inflammation, tumour stage and patient survival. PMID:30563990
Association of CHFR Promoter Methylation with Treatment Outcomes of Irinotecan-Based Chemotherapy in Metastatic Colorectal Cancer. PMID:30562637
Prognostic models for predicting overall survival in metastatic castration-resistant prostate cancer: a systematic review. PMID:30554274
Connexin 43 is an independent predictor of patient outcome in breast cancer patients. PMID:30474779
Calpain system protein expression and activity in ovarian cancer. PMID:30448882
A Meta-Analysis of Vascular Endothelial Growth Factor for Nasopharyngeal Cancer Prognosis. PMID:30430078
Prognostic impact of CDX2 in stage II colon cancer: results from two nationwide cohorts. PMID:30425348
Calcium-activated chloride channel regulator 1 as a prognostic biomarker in pancreatic ductal adenocarcinoma. PMID:30419838
Tumour deposits are a significant prognostic factor in gastric cancer - a systematic review and meta-analysis. PMID:30376189
Clinicopathological and prognostic correlations of HER3 expression and its degradation regulators, NEDD4-1 and NRDP1, in primary breast cancer. PMID:30367623
Cell-free DNA in cancer: current insights. PMID:30367445
The immunologic constant of rejection classification refines the prognostic value of conventional prognostic signatures in breast cancer. PMID:30353048
Co-expression of nuclear P38 and hormone receptors is prognostic of good long-term clinical outcome in primary breast cancer and is linked to upregulation of DNA repair. PMID:30352570
Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy. PMID:30291241
Androgen receptor expression in normal breast tissue and subsequent breast cancer risk. PMID:30276234
Prognostic values of long noncoding RNA PVT1 in various carcinomas: An updated systematic review and meta-analysis. PMID:30252166
Evaluation of the prognostic value of CD3, CD8, and FOXP3 mRNA expression in early-stage breast cancer patients treated with anthracycline-based adjuvant chemotherapy. PMID:30240146
Clinical Impact of Epithelial-to-Mesenchymal Transition Regulating MicroRNAs in Pancreatic Ductal Adenocarcinoma. PMID:30217058
Chromogenic Multiplex Immunohistochemistry Reveals Modulation of the Immune Microenvironment Associated with Survival in Elderly Patients with Lung Adenocarcinoma. PMID:30216999
Increased HSF1 expression predicts shorter disease-specific survival of prostate cancer patients following radical prostatectomy. PMID:30131848
A review of the most promising biomarkers for early diagnosis and prognosis prediction of tongue squamous cell carcinoma. PMID:30131545
MicroRNA-200 and microRNA-30 family as prognostic molecular signatures in ovarian cancer: A meta-analysis. PMID:30095616
MicroRNA dysregulation in adenoid cystic carcinoma of the salivary gland in relation to prognosis and gene fusion status: a cohort study. PMID:30069755
Survival Outcomes by TP53 Mutation Status in Metastatic Breast Cancer. PMID:30035249
Poor reporting of multivariable prediction model studies: towards a targeted implementation strategy of the TRIPOD statement. PMID:30021577
Intra-tumor molecular heterogeneity in breast cancer: definitions of measures and association with distant recurrence-free survival. PMID:29992418
ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer. PMID:29988110
Stanniocalcin 2 expression is associated with a favourable outcome in male breast cancer. PMID:29956502
The Prognostic Value of Tumor-Infiltrating lymphocytes in Stage II Colon Cancer. A Nationwide Population-Based Study. PMID:29940413
The association of the lymph node ratio and serum carbohydrate antigen 19-9 with early recurrence after curative gastrectomy for gastric cancer. PMID:29926189
Low expression of G protein-coupled oestrogen receptor 1 (GPER) is associated with adverse survival of breast cancer patients. PMID:29899833
Prognostic significance of immune cells in non-small cell lung cancer: meta-analysis. PMID:29872507
A gender specific improved survival related to stromal miR-143 and miR-145 expression in non-small cell lung cancer. PMID:29867125
High-serum MMP-8 levels are associated with decreased survival and systemic inflammation in colorectal cancer. PMID:29808017
The prognostic value of tumour stroma ratio and tumour budding in stage II colon cancer. A nationwide population-based study. PMID:29785462
Observational study of coagulation activation in early breast cancer: development of a prognostic model based on data from the real world setting. PMID:29769125
Tumour buds determine prognosis in resected pancreatic ductal adenocarcinoma. PMID:29755112
Gene expression in triple-negative breast cancer in relation to survival. PMID:29748761
Elevated serum RAS p21 is an independent prognostic factor in metastatic breast cancer. PMID:29739347
Glycine: a non-invasive imaging biomarker to aid magnetic resonance spectroscopy in the prediction of survival in paediatric brain tumours. PMID:29721167
Glucose transporter 1 expression as a marker of prognosis in oesophageal adenocarcinoma. PMID:29719622
Prognostic factors and prognostic models for renal cell carcinoma: a literature review. PMID:29713755
Loss of N-WASP drives early progression in an Apc model of intestinal tumourigenesis. PMID:29672847
Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study. PMID:29636300
Total iron-binding capacity is a novel prognostic marker after curative gastrectomy for gastric cancer. PMID:29633053
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. PMID:29625055
Prognostic DNA methylation markers for sporadic colorectal cancer: a systematic review. PMID:29564023
Expanding the Utilization of Formalin-Fixed, Paraffin-Embedded Archives: Feasibility of miR-Seq for Disease Exploration and Biomarker Development from Biopsies with Clear Cell Renal Cell Carcinoma. PMID:29534467
Reporting guidelines for oncology research: helping to maximise the impact of your research. PMID:29471308
Clinicopathological and functional implications of the inhibitor of apoptosis proteins survivin and XIAP in esophageal cancer. PMID:29467895
Breslow Density Is a Novel Prognostic Feature That Adds Value to Melanoma Staging. PMID:29462090
Simple decision-tree tool to facilitate author identification of reporting guidelines during submission: a before-after study. PMID:29451534
Clinical prediction models for mortality and functional outcome following ischemic stroke: A systematic review and meta-analysis. PMID:29377923
High nuclear MSK1 is associated with longer survival in breast cancer patients. PMID:29327245
Neoadjuvant radiochemotherapy decreases the total amount of tumor infiltrating lymphocytes, but increases the number of CD8+/Granzyme B+ (GrzB) cytotoxic T-cells in rectal cancer. PMID:29308324
Stromal Expression of MARCKS Protein in Ovarian Carcinomas Has Unfavorable Prognostic Value. PMID:29295532
IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients. PMID:29256156
Significance of Ki-67 in non-muscle invasive bladder cancer patients: a systematic review and meta-analysis. PMID:29246006
The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma. PMID:29235571
Heat shock protein 70 and tumor-infiltrating NK cells as prognostic indicators for patients with squamous cell carcinoma of the head and neck after radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG). PMID:29235112
Evaluation of serum epidermal growth factor receptor (EGFR) in correlation to circulating tumor cells in patients with metastatic breast cancer. PMID:29229933
Tumoral ANXA1 Is a Predictive Marker for Sunitinib Treatment of Renal Cancer Patients. PMID:29187872
MYC regulation of glutamine-proline regulatory axis is key in luminal B breast cancer. PMID:29169183
Clinical significance of CD73 in triple-negative breast cancer: multiplex analysis of a phase III clinical trial. PMID:29145561
TUG1, SPRY4-IT1, and HULC as valuable prognostic biomarkers of survival in cancer: A PRISMA-compliant meta-analysis. PMID:29145271
Evaluation of the proliferation marker Ki-67 in a large prostatectomy cohort. PMID:29141018
The Future of Radiobiology. PMID:29126306
Survivin and XIAP expression in distinct tumor compartments of surgically resected gastric cancer: XIAP as a prognostic marker in diffuse and mixed type adenocarcinomas. PMID:29109763
Development of an interstitial cystitis risk score for bladder permeability. PMID:29088231
The role of EZH2 in overall survival of colorectal cancer: a meta-analysis. PMID:29061982
Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer. PMID:29049607
Prognostic Value of the New Prostate Cancer International Society of Urological Pathology Grade Groups. PMID:29034236
Meta-analysis of SIRT1 expression as a prognostic marker for overall survival in gastrointestinal cancer. PMID:28977971
Tumor-infiltrating immune cells and prognosis in gastric cancer: a systematic review and meta-analysis. PMID:28977947
Elevated expression of ΔNp63 in advanced esophageal squamous cell carcinoma. PMID:28892579
Exploitation of Gene Expression and Cancer Biomarkers in Paving the Path to Era of Personalized Medicine. PMID:28813639
Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research. PMID:28777142
Discovery and validation of a colorectal cancer classifier in a new blood test with improved performance for high-risk subjects. PMID:28769740
Prognostic and predictive importance of the estrogen receptor coactivator AIB1 in a randomized trial comparing adjuvant letrozole and tamoxifen therapy in postmenopausal breast cancer: the Danish cohort of BIG 1-98. PMID:28766132
Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis. PMID:28751758
Loss of constitutive ABCB1 expression in breast cancer associated with worse prognosis. PMID:28670140
Evaluation of the Prognostic Value of RANK, OPG, and RANKL mRNA Expression in Early Breast Cancer Patients Treated with Anthracycline-Based Adjuvant Chemotherapy. PMID:28666187
Did the reporting of prognostic studies of tumour markers improve since the introduction of REMARK guideline? A comparison of reporting in published articles. PMID:28614415
Prognostic value of programmed cell death ligand 1 expression in patients with head and neck cancer: A systematic review and meta-analysis. PMID:28604812
MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer. PMID:28548126
Prognostic importance of circulating epidermal growth factor-like domain 7 in patients with metastatic colorectal cancer treated with chemotherapy and bevacizumab. PMID:28539619
Differential expression of VEGFR2 protein in HER2 positive primary human breast cancer: potential relevance to anti-angiogenic therapies. PMID:28533703
Diagnostic role of Wnt pathway gene promoter methylation in non small cell lung cancer. PMID:28422739
PDL1 expression is a poor-prognosis factor in soft-tissue sarcomas. PMID:28405501
S100β as a serum marker in endocrine resistant breast cancer. PMID:28399921
A Novel Numerical Scoring System for Melanoma Tumor-infiltrating Lymphocytes Has Better Prognostic Value Than Standard Scoring. PMID:28368925
Characterisation of male breast cancer: a descriptive biomarker study from a large patient series. PMID:28350011
The role of LINE-1 methylation in predicting survival among colorectal cancer patients: a meta-analysis. PMID:28343299
Tumoral cubilin is a predictive marker for treatment of renal cancer patients with sunitinib and sorafenib. PMID:28260162
Construction of a pathological risk model of occult lymph node metastases for prognostication by semi-automated image analysis of tumor budding in early-stage oral squamous cell carcinoma. PMID:28212555
Ten Years of Proteomics in Bladder Cancer: Progress and Future Directions. PMID:28149930
Clinical Significance of Early Changes in Circulating Tumor Cells from Patients Receiving First-Line Cisplatin-Based Chemotherapy for Metastatic Urothelial Carcinoma. PMID:28035320
MARCKS protein overexpression in inflammatory breast cancer. PMID:28009981
Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking. PMID:27992240
Prognostic Value of MammaPrint® in Invasive Lobular Breast Cancer. PMID:27980389
Prognostic values of DLK1 for surgery and imatinib mesylate adjuvant therapy in gastrointestinal stromal tumors. PMID:27904782
CD44 induces FOXP3 expression and is related with favorable outcome in breast carcinoma. PMID:27885422
Expression pattern of BCCIP in hepatocellular carcinoma is correlated with poor prognosis and enhanced cell proliferation. PMID:27832471
Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival. PMID:27798717
Reduced mRNA expression levels of NFE2L2 are associated with poor outcome in breast cancer patients. PMID:27770790
The association between dietary vitamin A intake and pancreatic cancer risk: a meta-analysis of 11 studies. PMID:27756825
Neutrophilia in locally advanced cervical cancer: A novel biomarker for image-guided adaptive brachytherapy? PMID:27713124
Prognostic effect of intratumoral neutrophils across histological subtypes of non-small cell lung cancer. PMID:27708229
Prognostic value of PDL1 expression in pancreatic cancer. PMID:27589570
PD-L1 expression in basaloid squamous cell lung carcinoma: Relationship to PD-1+ and CD8+ tumor-infiltrating T cells and outcome. PMID:27562497
Prognostic Role of Secretory Clusterin in Multiple Human Malignant Neoplasms: A Meta-Analysis of 26 Immunohistochemistry Studies. PMID:27532124
Assessment of the extent of unpublished studies in prognostic factor research: a systematic review of p53 immunohistochemistry in bladder cancer as an example. PMID:27531721
Circulating Tumour Cells as an Independent Prognostic Factor in Patients with Advanced Oesophageal Squamous Cell Carcinoma Undergoing Chemoradiotherapy. PMID:27530152
Clinical significance of TIPE expression in gastric carcinoma. PMID:27524904
Prognostic Impact of Epidermal Growth Factor Receptor Overexpression in Patients with Cervical Cancer: A Meta-Analysis. PMID:27438047
Subcellular differential expression of Ep-ICD in oral dysplasia and cancer is associated with disease progression and prognosis. PMID:27421772
Biomarker development in the precision medicine era: lung cancer as a case study. PMID:27388699
Assessment of clinically related outcomes and biomarker analysis for translational integration in colorectal cancer (ACROBATICC): study protocol for a population-based, consecutive cohort of surgically treated colorectal cancers and resected colorectal liver metastasis. PMID:27357108
Long noncoding RNAs as novel predictors of survival in human cancer: a systematic review and meta-analysis. PMID:27352941
Adverse prognostic impact of the CpG island methylator phenotype in metastatic colorectal cancer. PMID:27310704
Polypeptide N-acetylgalactosaminyltransferase-6 expression independently predicts poor overall survival in patients with lung adenocarcinoma after curative resection. PMID:27276675
Genetic variations in immunomodulatory pathways to predict survival in patients with locoregional gastric cancer. PMID:27241062
Clinical impact and network of determinants of tumour necrosis in colorectal cancer. PMID:27195424
Association between telomere length and survival in cancer patients: a meta-analysis and review of literature. PMID:27185042
PD-L1 and Tumor Infiltrating Lymphocytes as Prognostic Markers in Resected NSCLC. PMID:27104612
The Prognostic Value of Tumor-Infiltrating Lymphocytes in Breast Cancer: A Systematic Review and Meta-Analysis. PMID:27073890
Growth differentiation factor 15 is a promising diagnostic and prognostic biomarker in colorectal cancer. PMID:26990020
Tenascin-C serum levels and its prognostic power in non-small cell lung cancer. PMID:26967391
MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours. PMID:26954716
ER maleate is a novel anticancer agent in oral cancer: implications for cancer therapy. PMID:26934445
MMP2 and MMP9 serum levels are associated with favorable outcome in patients with inflammatory breast cancer treated with bevacizumab-based neoadjuvant chemotherapy in the BEVERLY-2 study. PMID:26921265
Expression levels of HER2 and MRP1 are not prognostic factors of long-term survival in 829 patients with esophageal squamous cell carcinoma. PMID:26870278
Prognostic value of polarized macrophages in patients with hepatocellular carcinoma after curative resection. PMID:26843477
Prognostic Effect of Tumor Lymphocytic Infiltration in Resectable Non-Small-Cell Lung Cancer. PMID:26834066
Tumour budding with and without admixed inflammation: two different sides of the same coin? PMID:26766735
Angiogenesis-Related Markers and Prognosis After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Metastatic Colorectal Cancer. PMID:26727921
Prognostic Value of Ezrin in Various Cancers: A Systematic Review and Updated Meta-analysis. PMID:26632332
Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a. PMID:26590814
Performance of the colorectal cancer screening marker Sept9 is influenced by age, diabetes and arthritis: a nested case-control study. PMID:26514170
Methodological issues in current practice may lead to bias in the development of biomarker combinations for predicting acute kidney injury. PMID:26398494
Prognostic significance of K-Ras mutation rate in metastatic colorectal cancer patients. PMID:26384309
Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer. PMID:26310568
Integrating Tumor and Stromal Gene Expression Signatures With Clinical Indices for Survival Stratification of Early-Stage Non-Small Cell Lung Cancer. PMID:26286589
Menacalc, a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer. PMID:26112005
Systematic review and meta-analysis of immunohistochemical prognostic biomarkers in resected oesophageal adenocarcinoma. PMID:26110972
Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas. PMID:26071182
SNPs at miR-155 binding sites of TYRP1 explain discrepancy between mRNA and protein and refine TYRP1 prognostic value in melanoma. PMID:26068396
miR-30e* is an independent subtype-specific prognostic marker in breast cancer. PMID:26057454
Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer. PMID:25989272
TEM7 (PLXDC1), a key prognostic predictor for resectable gastric cancer, promotes cancer cell migration and invasion. PMID:25973314
The prognostic significance of HOTAIR for predicting clinical outcome in patients with digestive system tumors. PMID:25968902
PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy. PMID:25940795
Prediction of recurrence-free survival using a protein expression-based risk classifier for head and neck cancer. PMID:25893634
What affects authors' and editors' use of reporting guidelines? Findings from an online survey and qualitative interviews. PMID:25875918
Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort. PMID:25871393
Phosphoglycerate kinase-1 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in breast cancer. PMID:25867275
Prognostic value of neutrophil to lymphocyte ratio for gastric cancer. PMID:25861605
Wilms' tumor 1 (WT1) expression and prognosis in solid cancer patients: a systematic review and meta-analysis. PMID:25748047
Prognostic and predictive value of PDL1 expression in breast cancer. PMID:25669979
High nuclear hypoxia-inducible factor 1 alpha expression is a predictor of distant recurrence in patients with resected pancreatic adenocarcinoma. PMID:25596110
Prognostic significance of cytoplasmic S100A2 overexpression in oral cancer patients. PMID:25591983
Changes in circulating microRNA-126 during treatment with chemotherapy and bevacizumab predicts treatment response in patients with metastatic colorectal cancer. PMID:25584492
The prognostic value of cyclin D1 expression in head and neck squamous cell carcinoma. PMID:25516222
The value of tumor infiltrating lymphocytes (TILs) for predicting response to neoadjuvant chemotherapy in breast cancer: a systematic review and meta-analysis. PMID:25501357
RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1. PMID:25456366
Topo2A as a prognostic biomarker for patients with resectable esophageal squamous cell carcinomas. PMID:25432700
Bcl-2 expression and patient survival in gastric cancer: a systematic review of the literature with meta-analysis. PMID:25428392
Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium study. PMID:25349970
Critical appraisal and data extraction for systematic reviews of prediction modelling studies: the CHARMS checklist. PMID:25314315
IL6 genotype, tumour ER-status, and treatment predicted disease-free survival in a prospective breast cancer cohort. PMID:25305747
p53 is an independent prognostic factor in operable esophageal squamous cell carcinoma: a large-scale study with a long follow-up. PMID:25270283
Prognostic value of polycomb proteins EZH2, BMI1 and SUZ12 and histone modification H3K27me3 in colorectal cancer. PMID:25243792
The TRAIL system is over-expressed in breast cancer and FLIP a marker of good prognosis. PMID:25230899
Correlation of chitinase 3-like 1 single nucleotide polymorphisms and haplotypes with uterine cervical cancer in Taiwanese women. PMID:25203433
The prognostic value of microRNA-126 and microvessel density in patients with stage II colon cancer: results from a population cohort. PMID:25199818
Characterisation and prognostic value of tertiary lymphoid structures in oral squamous cell carcinoma. PMID:25177210
A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer. PMID:25169931
Methylated Glutathione S-transferase 1 (mGSTP1) is a potential plasma free DNA epigenetic marker of prognosis and response to chemotherapy in castrate-resistant prostate cancer. PMID:25144624
High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients. PMID:25139823
Pretherapeutic gamma-glutamyltransferase is an independent prognostic factor for patients with renal cell carcinoma. PMID:25117808
Relevance of insulin-like growth factor 1 receptor gene expression as a prognostic factor in non-small-cell lung cancer. PMID:25081930
Redefining high-risk patients with stage II colon cancer by risk index and microRNA-21: results from a population-based cohort. PMID:25051407
Genomic prostate cancer classifier predicts biochemical failure and metastases in patients after postoperative radiation therapy. PMID:25035207
Evaluation of a chemoresponse assay as a predictive marker in the treatment of recurrent ovarian cancer: further analysis of a prospective study. PMID:25003664
Tropomyosin-related receptor kinase B at the invasive front and tumour cell dedifferentiation in gastric cancer. PMID:24853179
Prognostic role of FGFR1 amplification in early-stage non-small cell lung cancer. PMID:24853178
Computed tomography (CT) perfusion as an early predictive marker for treatment response to neoadjuvant chemotherapy in gastroesophageal junction cancer and gastric cancer--a prospective study. PMID:24845062
Clinical prognostic value of combined analysis of Aldh1, Survivin, and EpCAM expression in colorectal cancer. PMID:24786601
A data standard for sourcing fit-for-purpose biological samples in an integrated virtual network of biobanks. PMID:24785371
Amplification of TRIM44: pairing a prognostic target with potential therapeutic strategy. PMID:24777112
Urinary protein biomarker panel for the detection of recurrent bladder cancer. PMID:24714076
Tumour-associated endothelial-FAK correlated with molecular sub-type and prognostic factors in invasive breast cancer. PMID:24693876
Invasive breast cancer: stratification of histological grade by gene-based assays: a still relevant example from an older data set. PMID:24673556
Clinical and prognostic significance of HIF-1α, PTEN, CD44v6, and survivin for gastric cancer: a meta-analysis. PMID:24647137
The expression of ribonucleotide reductase M2 in the carcinogenesis of uterine cervix and its relationship with clinicopathological characteristics and prognosis of cancer patients. PMID:24637958
Activation of the PI3K/AKT pathway correlates with prognosis in stage II colon cancer. PMID:24619078
Clinical significance of polypeptide N-acetylgalactosaminyl transferase-5 (GalNAc-T5) expression in patients with gastric cancer. PMID:24619076
Prognostic significance of lymphovascular invasion in radical cystectomy on patients with bladder cancer: a systematic review and meta-analysis. PMID:24586637
Dietary carrot consumption and the risk of prostate cancer. PMID:24519559
Tumour-infiltrating inflammation and prognosis in colorectal cancer: systematic review and meta-analysis. PMID:24504370
Tissue prognostic biomarkers in primary cutaneous melanoma. PMID:24487785
Prognostic value of microRNA expression in operable non-small cell lung cancer patients. PMID:24448358
BMC Medicine: a decade of open access medical research. PMID:24405514
Future directions for monitoring treatment responses in breast cancer. PMID:24396499
Extramural venous invasion is a potential imaging predictive biomarker of neoadjuvant treatment in rectal cancer. PMID:24300971
Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer. PMID:24220694
C-reactive protein and long-term ischemic stroke prognosis. PMID:24211144
Systematic review and meta-analysis of tumor biomarkers in predicting prognosis in esophageal cancer. PMID:24206575
Prognostic role of survivin in bladder cancer: a systematic review and meta-analysis. PMID:24204662
Tetraspanins CD9 and CD151, epidermal growth factor receptor and cyclooxygenase-2 expression predict malignant progression in oral epithelial dysplasia. PMID:24201754
Tumour-infiltrating lymphocytes predict for outcome in HPV-positive oropharyngeal cancer. PMID:24169344
Germline genetic variants in ABCB1, ABCC1 and ALDH1A1, and risk of hematological and gastrointestinal toxicities in a SWOG Phase III trial S0221 for breast cancer. PMID:23999597
TNFAIP8 as a predictor of metastasis and a novel prognostic biomarker in patients with epithelial ovarian cancer. PMID:23982604
Prognostic significance of ESR1 amplification and ESR1 PvuII, CYP2C19*2, UGT2B15*2 polymorphisms in breast cancer patients. PMID:23951298
Prognostic role of lemur tyrosine kinase-3 germline polymorphisms in adjuvant gastric cancer in Japan and the United States. PMID:23918832
The prognostic value of CDKN2A hypermethylation in colorectal cancer: a meta-analysis. PMID:23703248
Geographic analysis of RKIP expression and its clinical relevance in colorectal cancer. PMID:23632477
Cytokeratin 19-fragments (CYFRA 21-1) as a novel serum biomarker for response and survival in patients with advanced pancreatic cancer. PMID:23579210
GERD-Barrett-Adenocarcinoma: Do We Have Suitable Prognostic and Predictive Molecular Markers? PMID:23573078
Genetic associations with toxicity-related discontinuation of aromatase inhibitor therapy for breast cancer. PMID:23546553
Tyrosinase-related protein 1 mRNA expression in lymph node metastases predicts overall survival in high-risk melanoma patients. PMID:23519055
Prognosis Research Strategy (PROGRESS) 2: prognostic factor research. PMID:23393429
The international effort: building the bridge for Translational Medicine: Report of the 1st International Conference of Translational Medicine (ICTM). PMID:23369397
Germline DNA copy number aberrations identified as potential prognostic factors for breast cancer recurrence. PMID:23342018
Prognostic value of CA 19-9, CEA, CRP, LDH and bilirubin levels in locally advanced and metastatic pancreatic cancer: results from a multicenter, pooled analysis of patients receiving palliative chemotherapy. PMID:23315099
CLEIA CA125 evidences: good analytical performance avoiding "Hook effect". PMID:23111756
Comparative effectiveness research, genomics-enabled personalized medicine, and rapid learning health care: a common bond. PMID:23071236
Publication of tumor marker research results: the necessity for complete and transparent reporting. PMID:23071235
Cyclooxygenase-2 expression in bladder cancer and patient prognosis: results from a large clinical cohort and meta-analysis. PMID:23028744
Multi-level evidence that circulating CK18 is a biomarker of tumour burden in colorectal cancer. PMID:22996610
Expression profiling of stem cell-related genes in neoadjuvant-treated gastric cancer: a NOTCH2, GSK3B and β-catenin gene signature predicts survival. PMID:22970250
Prognostic utility of pre-operative circulating osteopontin, carbonic anhydrase IX and CRP in renal cell carcinoma. PMID:22918393
New biomarkers and targets in pancreatic cancer and their application to treatment. PMID:22733351
Fracture risk assessment: state of the art, methodologically unsound, or poorly reported? PMID:22688862
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration. PMID:22675273
Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration. PMID:22642691
The clinical use of biomarkers as prognostic factors in Ewing sarcoma. PMID:22587879
Pancreatic cancer: translational research aspects and clinical implications. PMID:22509073
Prognostic value of TOP2A gene amplification and chromosome 17 polysomy in early breast cancer. PMID:22426810
Cancer biomarkers. PMID:22356776
Clinical significance of CD151 overexpression in subtypes of invasive breast cancer. PMID:22294188
Soluble epidermal growth factor receptor (sEGFR) and carcinoembryonic antigen (CEA) concentration in patients with non-small cell lung cancer: correlation with survival after erlotinib and gefitinib treatment. PMID:22276032
Effect of using reporting guidelines during peer review on quality of final manuscripts submitted to a biomedical journal: masked randomised trial. PMID:22108262
Expression of AIB1 protein as a prognostic factor in breast cancer. PMID:22035181
Cytokeratin-19 and mammaglobin gene expression in circulating tumor cells from metastatic breast cancer patients enrolled in North Central Cancer Treatment Group trials, N0234/336/436/437. PMID:21976532
Developing risk prediction models for type 2 diabetes: a systematic review of methodology and reporting. PMID:21902820
MET phosphorylation predicts poor outcome in small cell lung carcinoma and its inhibition blocks HGF-induced effects in MET mutant cell lines. PMID:21847116
Biomarkers of clinical benefit for anti-epidermal growth factor receptor agents in patients with non-small-cell lung cancer. PMID:21654681
The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis. PMID:21629244
Tetraspanin CD151 is a novel prognostic marker in poor outcome endometrial cancer. PMID:21505452
Thymidylate synthase as a prognostic biomarker for locally advanced rectal cancer after multimodal treatment. PMID:21347782
Oral dysplasia: biomarkers, treatment, and follow-up. PMID:21249481
Serum biomarkers for improved diagnostic of pancreatic cancer: a current overview. PMID:21193998
Systems pathology. PMID:21172088
Biomarkers in Barrett's esophagus and esophageal adenocarcinoma: predictors of progression and prognosis. PMID:21128316
Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer. PMID:21063398
Estimation and external validation of a new prognostic model for predicting recurrence-free survival for early breast cancer patients in the UK. PMID:20823886
Genomic architecture characterizes tumor progression paths and fate in breast cancer patients. PMID:20592421
TGFBI expression is associated with a better response to chemotherapy in NSCLC. PMID:20509890
Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial. PMID:20005174
Reporting of prognostic studies of tumour markers: a review of published articles in relation to REMARK guidelines. PMID:19997101
A multimarker prognostic assay for primary cutaneous melanoma. PMID:19887476
High frequency of tumor cells with nuclear Egr-1 protein expression in human bladder cancer is associated with disease progression. PMID:19878561
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis. PMID:19840191
Pre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma. PMID:19789534
Modest effect of p53, EGFR and HER-2/neu on prognosis in epithelial ovarian cancer: a meta-analysis. PMID:19513073
Prognostic markers in cancer: the evolution of evidence from single studies to meta-analysis, and beyond. PMID:19367280
Molecular classification of solid tumours: towards pathway-driven therapeutics. PMID:19367275
Cerebrospinal fluid biomarkers in Guillain-Barré syndrome--where do we stand? PMID:19267167
Modelling prognostic factors in advanced pancreatic cancer. PMID:19238630
Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer. PMID:18986507
The ErbB signalling pathway: protein expression and prognostic value in epithelial ovarian cancer. PMID:18628764
Guidelines for reporting health research: the EQUATOR network's survey of guideline authors. PMID:18578566
Combined analysis of VEGF and EGFR predicts complete tumour response in rectal cancer treated with preoperative radiotherapy. PMID:18182986
Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. PMID:17941715
The role of MUC1 and MUC3 in the biology and prognosis of colorectal cancer. PMID:17349047
Interpretation of microarray data in cancer. PMID:17342085
Factors influencing p53 expression in ovarian cancer as a biomarker of clinical outcome in multicentre studies. PMID:16880779
Immunohistochemical markers of prognosis in non-small cell lung cancer: a review and proposal for a multiphase approach to marker evaluation. PMID:16873561
REporting recommendations for tumour MARKer prognostic studies (REMARK). PMID:16106244 -
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration
PubMed citations: 333.
333 articles citing: Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): explanation and elaboration
A single-nucleotide-polymorphism in the 5'-flanking region of MSX1 gene as a predictive marker candidate for platinum-based therapy of esophageal carcinoma. PMID:35251318
Cell Division Cycle-Associated Genes Are Potential Immune Regulators in Nasopharyngeal Carcinoma. PMID:35237510
Fear of movement and emotional distress as prognostic factors for disability in patients with shoulder pain: a prospective cohort study. PMID:35219313
HOXB9 Overexpression Promotes Colorectal Cancer Progression and Is Associated with Worse Survival in Liver Resection Patients for Colorectal Liver Metastases. PMID:35216396
SERS Liquid Biopsy Profiling of Serum for the Diagnosis of Kidney Cancer. PMID:35203443
SPDL1 Is an Independent Predictor of Patient Outcome in Colorectal Cancer. PMID:35163739
c-MET/VEGFR-2 co-localisation impacts on survival following bevacizumab therapy in epithelial ovarian cancer: an exploratory biomarker study of the phase 3 ICON7 trial. PMID:35144591
Multimodal analysis suggests differential immuno-metabolic crosstalk in lung squamous cell carcinoma and adenocarcinoma. PMID:35087143
Racial differences in breast cancer outcomes by hepatocyte growth factor pathway expression. PMID:35034243
Pre- and Perioperative Inflammatory Biomarkers in Older Patients Resected for Localized Colorectal Cancer: Associations with Complications and Prognosis. PMID:35008324
Shared Gene Expression and Immune Pathway Changes Associated with Progression from Nevi to Melanoma. PMID:35008167
Identification of Morphologic Criteria Associated with Biochemical Recurrence in Intraductal Carcinoma of the Prostate. PMID:34944863
Prognostic value of miR-21 for prostate cancer: a systematic review and meta-analysis. PMID:34931228
Impact of Serum γ-Glutamyltransferase on Overall Survival in Men with Metastatic Castration-Resistant Prostate Cancer Treated with Docetaxel. PMID:34771748
Mammographic density, endocrine therapy and breast cancer risk: a prognostic and predictive biomarker review. PMID:34697802
Programmed cell death 10 promotes metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma via PP2Ac-mediated YAP activation. PMID:34521817
Proteomics-derived basal biomarker DNA-PKcs is associated with intrinsic subtype and long-term clinical outcomes in breast cancer. PMID:34504086
Prognostic Role of EGFR/p-EGFR in Patients With Nasopharyngeal Carcinoma: A Meta-Analysis. PMID:34490092
Orthogonal MET analysis in a population-representative stage II-III colon cancer cohort: prognostic and potential therapeutic implications. PMID:34428346
Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors. PMID:34372942
Plasma Metabolome Profiling Identifies Metabolic Subtypes of Pancreatic Ductal Adenocarcinoma. PMID:34359990
It's not 'just a tube of blood': principles of protocol development, sample collection, staffing and budget considerations for blood-based biomarkers in immunotherapy studies. PMID:34321277
The prognostic utility of pre-treatment neutrophil-to-lymphocyte-ratio (NLR) in colorectal cancer: A systematic review and meta-analysis. PMID:34308567
Role of Oncofetal Protein CR-1 as a Potential Tumor Marker for Oral Squamous Cell Carcinoma. PMID:34220003
The Prognostic Impact of Intratumoral Aryl Hydrocarbon Receptor in Primary Breast Cancer Depends on the Type of Endocrine Therapy: A Population-Based Cohort Study. PMID:34094928
PAI-1 expression in intratumoral inflammatory infiltrate contributes to lymph node metastasis in oral cancer: A cross-sectional study. PMID:34094525
An integrative microenvironment approach for laryngeal carcinoma: the role of immune/methylation/autophagy signatures on disease clinical prognosis and single-cell genotypes. PMID:34093817
Non-Invasive Biomarkers for Earlier Detection of Pancreatic Cancer-A Comprehensive Review. PMID:34072842
Texture Analysis of Fractional Water Content Images Acquired during PET/MRI: Initial Evidence for an Association with Total Lesion Glycolysis, Survival and Gene Mutation Profile in Primary Colorectal Cancer. PMID:34072712
ZNF-281 as the Potential Diagnostic Marker of Oral Squamous Cell Carcinoma. PMID:34071380
Circulating Forms of Urokinase-Type Plasminogen Activator Receptor in Plasma Can Predict Recurrence and Survival in Patients with Urothelial Carcinoma of the Bladder. PMID:34069121
Expression of Cancer Testis Antigens in Tumor-Adjacent Normal Liver Is Associated with Post-Resection Recurrence of Hepatocellular Carcinoma. PMID:34065388
The immunotherapeutic role of indoleamine 2,3-dioxygenase in head and neck squamous cell carcinoma: A systematic review. PMID:34053179
Tumor-stroma ratio is associated with Miller-Payne score and pathological response to neoadjuvant chemotherapy in HER2-negative early breast cancer. PMID:34043821
Machine Learning Identifies Metabolic Signatures that Predict the Risk of Recurrent Angina in Remitted Patients after Percutaneous Coronary Intervention: A Multicenter Prospective Cohort Study. PMID:34026445
EPAC-lung: European pooled analysis of the prognostic value of circulating tumour cells in small cell lung cancer. PMID:34012782
The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer. PMID:33931939
NM23-H1 Expression of Head and Neck Squamous Cell Carcinoma in Association With the Response to Irradiation. PMID:33859945
PAM50 Intrinsic Subtype Profiles in Primary and Metastatic Breast Cancer Show a Significant Shift toward More Aggressive Subtypes with Prognostic Implications. PMID:33808271
Combined In Situ Hybridization and Immunohistochemistry on Archival Tissues Reveals Stromal microRNA-204 as Prognostic Biomarker for Oral Squamous Cell Carcinoma. PMID:33804049
Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer. PMID:33796412
SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation. PMID:33658304
HER2 Expression Is Predictive of Survival in Cetuximab Treated Patients with RAS Wild Type Metastatic Colorectal Cancer. PMID:33562755
Transcriptomic biomarkers for predicting response to neoadjuvant treatment in oesophageal cancer. PMID:33442473
The Potential of Soluble Human Leukocyte Antigen Molecules for Early Cancer Detection and Therapeutic Vaccine Design. PMID:33353014
Towards biomarkers for outcomes after pancreatic ductal adenocarcinoma and ischaemic stroke, with focus on (co)-morbidity and ageing/cellular senescence (SASKit): protocol for a prospective cohort study. PMID:33334830
Identification of RASSF1A promoter hypermethylation as a biomarker for hepatocellular carcinoma. PMID:33292241
Biobanking for Cancer Biomarker Research: Issues and Solutions. PMID:33192050
PD-1 protein and gene expression as prognostic factors in early breast cancer. PMID:33172959
Increased Serum Level of Interleukin-10 Predicts Poor Survival and Early Recurrence in Patients With Peripheral T-Cell Lymphomas. PMID:33154947
Prognostic and predictive parameters in breast pathology: a pathologist's primer. PMID:33154551
The immune phenotype of tongue squamous cell carcinoma predicts early relapse and poor prognosis. PMID:33047888
Serum cytokine profile as a potential prognostic tool in colorectal cancer patients - one center study. PMID:32982592
Association of mismatch repair status with survival and response to neoadjuvant chemo(radio)therapy in rectal cancer. PMID:32964128
TRIPOD statement: a preliminary pre-post analysis of reporting and methods of prediction models. PMID:32948578
Prognostic and predictive significance of nuclear HIF1α expression in locally advanced HNSCC patients treated with chemoradiation with or without nimotuzumab. PMID:32939054
Clinicopathological and Prognostic Value of Gastric Carcinoma Highly Expressed Transcript 1 in Cancer: A Meta-Analysis. PMID:32908508
Biomarkers of progression to oral cancer in patients with dysplasia: A systematic review. PMID:32874572
Novel hematological biomarkers predict survival in renal cell carcinoma patients treated with nephrectomy. PMID:32863995
A Systematic Approach to Review of in vitro Methods in Brain Tumour Research (SAToRI-BTR): Development of a Preliminary Checklist for Evaluating Quality and Human Relevance. PMID:32850761
SOX1 Promoter Hypermethylation as a Potential Biomarker for High-Grade Squamous Intraepithelial Neoplasia Lesion and Cervical Carcinoma: A Meta-Analysis With Trial Sequential Analysis. PMID:32849763
Performance of Gene Expression Profile Tests for Prognosis in Patients With Localized Cutaneous Melanoma: A Systematic Review and Meta-analysis. PMID:32745161
Associations between muscle measures, survival, and toxicity in patients with limited stage small cell lung cancer. PMID:32725772
BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer. PMID:32711554
Oral squamous cell carcinoma diagnosed from saliva metabolic profiling. PMID:32601197
The relationships between systemic cytokine profiles and inflammatory markers in colorectal cancer and the prognostic significance of these parameters. PMID:32488137
The promise and challenge of cancer microbiome research. PMID:32487228
Prognostic value of lymph node ratio in laryngeal and hypopharyngeal squamous cell carcinoma: a systematic review and meta-analysis. PMID:32471483
A novel prognostic two-gene signature for triple negative breast cancer. PMID:32404959
Combined CCNE1 high-level amplification and overexpression is associated with unfavourable outcome in tubo-ovarian high-grade serous carcinoma. PMID:32391646
Expression and Significance of Immune Checkpoints in Clear Cell Carcinoma of the Uterine Cervix. PMID:32322590
Expression of epithelial-mesenchymal transition-related markers and phenotypes during breast cancer progression. PMID:32300922
Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer. PMID:32296755
State of the art in selection of variables and functional forms in multivariable analysis-outstanding issues. PMID:32266321
Risk Models for Breast Cancer and Their Validation. PMID:32226220
Validation of Novel Prognostic Biomarkers for Early-Stage Clear-Cell, Endometrioid and Mucinous Ovarian Carcinomas Using Immunohistochemistry. PMID:32133296
Anastrozole has an Association between Degree of Estrogen Suppression and Outcomes in Early Breast Cancer and is a Ligand for Estrogen Receptor α. PMID:32098767
From laboratory to clinic: Translation of extracellular vesicle based cancer biomarkers. PMID:32061674
Pilot Study to Establish a Novel Five-Gene Biomarker Panel for Predicting Lymph Node Metastasis in Patients With Early Stage Endometrial Cancer. PMID:32039004
PD-1/PD-L1 expression and tumor-infiltrating lymphocytes are prognostically favorable in advanced high-grade serous ovarian carcinoma. PMID:31980961
Prognostic value of the immunohistochemical detection of epithelial-mesenchymal transition biomarkers in oral epithelial dysplasia: A systematic review. PMID:31967982
Up-regulation of the tumor promoter Glyoxalase-1 indicates poor prognosis in breast cancer. PMID:31966428
Up-regulation of Wnt7b rather than Wnt1, Wnt7a, and Wnt9a indicates poor prognosis in breast cancer. PMID:31949853
Interim PET-results for prognosis in adults with Hodgkin lymphoma: a systematic review and meta-analysis of prognostic factor studies. PMID:31930780
Predictive Blood-Based Biomarkers in Patients with Epithelial Ovarian Cancer Treated with Carboplatin and Paclitaxel with or without Bevacizumab: Results from GOG-0218. PMID:31919136
Response: Letter regarding "The prognostic value of p16 and p53 expression for survival after vulvar cancer: A systematic review and meta-analysis". PMID:31867428
TMPRSS4: A Novel Tumor Prognostic Indicator for the Stratification of Stage IA Tumors and a Liquid Biopsy Biomarker for NSCLC Patients. PMID:31817025
Prognostic and clinical significance of long non-coding RNA HNF1A-AS1 in solid cancers: A systematic review and meta-analysis. PMID:31804362
Sexual dimorphism in gastric cancer: tumor-associated neutrophils predict patient outcome only for women. PMID:31741042
NPY Gene Methylation as a Universal, Longitudinal Plasma Marker for Evaluating the Clinical Benefit from Last-Line Treatment with Regorafenib in Metastatic Colorectal Cancer. PMID:31731482
Genotyping KRAS and EGFR Mutations in Greek Patients With Non-small-cell Lung Cancer: Incidence, Significance and Implications for Treatment. PMID:31659106
Systematic review and REMARK scoring of renal cell carcinoma prognostic circulating biomarker manuscripts. PMID:31639128
Toward Improving Practices for Submission of Diagnostic Tissue Blocks for National Cancer Institute Clinical Trials. PMID:31613330
Biomarkers for Evaluating the Inflammation Status in Patients with Cancer. PMID:31598370
Prognostic impact of Ki-67 proliferative index in resectable pancreatic ductal adenocarcinoma. PMID:31592095
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse. PMID:31591595
Circular RNAs in Clear Cell Renal Cell Carcinoma: Their Microarray-Based Identification, Analytical Validation, and Potential Use in a Clinico-Genomic Model to Improve Prognostic Accuracy. PMID:31575051
Associations of MGMT promoter hypermethylation with squamous intraepithelial lesion and cervical carcinoma: A meta-analysis. PMID:31574102
Prognostic Value of Blood Lactate and Base Deficit in Refractory Cardiac Arrest Cases Undergoing Extracorporeal Life Support. PMID:31572993
Diagnostic Tumor Markers in Head and Neck Squamous Cell Carcinoma (HNSCC) in the Clinical Setting. PMID:31555588
Comparison of the 7th and 8th Edition of the UICC/AJCC TNM Staging System in Primary Resected Squamous Cell Carcinomas of the Lung-A Single Center Analysis of 354 Cases. PMID:31552253
A study protocol for the development and internal validation of a multivariable prognostic model to determine lower extremity muscle injury risk in elite football (soccer) players, with further exploration of prognostic factors. PMID:31548994
Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas. PMID:31533654
Interim PET-results for prognosis in adults with Hodgkin lymphoma: a systematic review and meta-analysis of prognostic factor studies. PMID:31525824
Mismatch repair protein loss in breast cancer: clinicopathological associations in a large British Columbia cohort. PMID:31522348
BolA family member 2 enhances cell proliferation and predicts a poor prognosis in hepatocellular carcinoma with tumor hemorrhage. PMID:31413749
Long noncoding RNA DANCR in various cancers: a meta-analysis and bioinformatics. PMID:31410056
Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A. PMID:31300350
High GCLC level in tumor tissues is associated with poor prognosis of hepatocellular carcinoma after curative resection. PMID:31293636
Cumulative Antibiotic Use Significantly Decreases Efficacy of Checkpoint Inhibitors in Patients with Advanced Cancer. PMID:31292268
Prognostic Value of Blood Lactate and Lactate Clearance in Refractory Cardiac Arrest Treated by Extracorporeal Life Support. PMID:31276111
SETER/PR: a robust 18-gene predictor for sensitivity to endocrine therapy for metastatic breast cancer. PMID:31231679
Performance of preoperative plasma tumor markers HE4 and CA125 in predicting ovarian cancer mortality in women with epithelial ovarian cancer. PMID:31220149
Biospecimens and Molecular and Cellular Biomarkers in Aneurysmal Subarachnoid Hemorrhage Studies: Common Data Elements and Standard Reporting Recommendations. PMID:31144274
Prognostic value of long noncoding RNA ROR in patients with cancer in China: A systematic review and meta-analysis. PMID:31124961
Understanding the predictive value of continuous markers for censored survival data using a likelihood ratio approach. PMID:31117940
The current application of the Royston-Parmar model for prognostic modeling in health research: a scoping review. PMID:31093554
Prognosis research ideally should measure time-varying predictors at their intended moment of use. PMID:31093533
Prognostic value of long non-coding RNA ZEB1-AS1 in Chinese cancer patients: A Meta-analysis. PMID:31027073
A parsimonious 3-gene signature predicts clinical outcomes in an acute myeloid leukemia multicohort study. PMID:31015209
Dynamics of circulating vascular endothelial growth factor-A predict benefit from antiangiogenic cediranib in metastatic or recurrent cervical cancer patients. PMID:30980733
A robust panel based on tumour microenvironment genes for prognostic prediction and tailoring therapies in stage I-III colon cancer. PMID:30917936
Meta-analysis of the prognostic value of lncRNA DANCR for cancer patients in China. PMID:30881127
epiCaPture: A Urine DNA Methylation Test for Early Detection of Aggressive Prostate Cancer. PMID:30801051
The use of digital pathology and image analysis in clinical trials. PMID:30767396
Clinical significance of exosomes as potential biomarkers in cancer. PMID:30705894
Prognostic value of microRNAs in lung cancer: A systematic review and meta-analysis. PMID:30655979
The prolonged interval between induction chemotherapy and radiotherapy is associated with poor prognosis in patients with nasopharyngeal carcinoma. PMID:30654815
Assessment of Nuclear ZEB2 as a Biomarker for Colorectal Cancer Outcome and TNM Risk Stratification. PMID:30646224
Expression of RET is associated with Oestrogen receptor expression but lacks prognostic significance in breast cancer. PMID:30621641
Immune cell infiltration as a biomarker for the diagnosis and prognosis of stage I-III colon cancer. PMID:30564892
Meta-analysis of the prognostic value of long non-coding RNA PVT1 for cancer patients. PMID:30544468
High PD-L1 expression in the tumour cells did not correlate with poor prognosis of patients suffering for oral squamous cells carcinoma: A meta-analysis of the literature. PMID:30443950
Plasma Tie2 is a tumor vascular response biomarker for VEGF inhibitors in metastatic colorectal cancer. PMID:30405103
Dimensions of hepatocellular carcinoma phenotypic diversity. PMID:30386103
Interactions Between ABCB1 Genotype and Preoperative Statin Use Impact Clinical Outcomes Among Breast Cancer Patients. PMID:30370250
Cell-free DNA in cancer: current insights. PMID:30367445
Overinterpretation and misreporting of prognostic factor studies in oncology: a systematic review. PMID:30353050
Tumor Sidedness and Enriched Gene Groups for Efficacy of First-line Cetuximab Treatment in Metastatic Colorectal Cancer. PMID:30275242
miR-9-5p in Nephrectomy Specimens is a Potential Predictor of Primary Resistance to First-Line Treatment with Tyrosine Kinase Inhibitors in Patients with Metastatic Renal Cell Carcinoma. PMID:30201928
MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges. PMID:30189035
Prognostic and clinicopathological significance of DEPTOR expression in cancer patients: a meta-analysis. PMID:30174446
Prognostic role of neutrophil-to-lymphocyte ratio in diffuse large B cell lymphoma patients: an updated dose-response meta-analysis. PMID:30166942
Sprouty2 suppresses progression and correlates to favourable prognosis of intrahepatic cholangiocarcinoma via antagonizing FGFR2 signalling. PMID:30160357
Profiles of immune infiltration in colorectal cancer and their clinical significant: A gene expression-based study. PMID:30117315
The role of lncRNA CASC2 on prognosis of malignant tumors: a meta-analysis and bioinformatics. PMID:30100741
APOBEC3B gene expression as a novel predictive factor for pathological complete response to neoadjuvant chemotherapy in breast cancer. PMID:30093965
Identification of DAPK1 Promoter Hypermethylation as a Biomarker for Intra-Epithelial Lesion and Cervical Cancer: A Meta-Analysis of Published Studies, TCGA, and GEO Datasets. PMID:30065752
Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study. PMID:30062862
The Prosigna gene expression assay and responsiveness to adjuvant cyclophosphamide-based chemotherapy in premenopausal high-risk patients with breast cancer. PMID:30053900
Using microRNAs as Novel Predictors of Urologic Cancer Survival: An Integrated Analysis. PMID:30037718
MicroRNA-29c restores cisplatin sensitivity in liver cancer through direct inhibition of sirtuin 1 expression. PMID:30008835
Prognostic and clinicopathological significance of MLKL expression in cancer patients: a meta-analysis. PMID:30005626
CXCR7 expression in diffuse large B-cell lymphoma identifies a subgroup of CXCR4+ patients with good prognosis. PMID:29920526
Heterogeneity in Metastatic Breast Cancer 18F-Fluoroestradiol Uptake: Clinically Actionable, Biologically Illuminating? PMID:29903931
Melanoma Immunotherapy: Next-Generation Biomarkers. PMID:29896449
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): An Abridged Explanation and Elaboration. PMID:29873743
Clean Colorectum at Diagnostic Colonoscopy: Subsequent Detection of Extracolonic Malignancies by Plasma Protein Biomarkers? PMID:29872358
Prognostic role of carcinoembryonic antigen and carbohydrate antigen 19-9 in metastatic colorectal cancer: a BRAF-mutant subset with high CA 19-9 level and poor outcome. PMID:29872151
The combined presence of CD20 + B cells and PD-L1 + tumor-infiltrating lymphocytes in inflammatory breast cancer is prognostic of improved patient outcome. PMID:29858752
Diagnostic and Prognostic Potential of MicroRNA Maturation Regulators Drosha, AGO1 and AGO2 in Urothelial Carcinomas of the Bladder. PMID:29857476
Low expression of long noncoding RNA MT1JP is associated with poor overall survival in gastric cancer patients: Protocol for meta-analysis. PMID:29794726
A novel protein-based prognostic signature improves risk stratification to guide clinical management in early-stage lung adenocarcinoma patients. PMID:29756233
Prognostic significance of CXCL5 expression in cancer patients: a meta-analysis. PMID:29743818
Peritumoral overexpression of ZBP-89 is associated with unfavorable disease-free survival rates in patients with hepatocellular carcinoma following hepatectomy. PMID:29731904
Development of a stress response therapy targeting aggressive prostate cancer. PMID:29720449
Discovery of a Glucocorticoid Receptor (GR) Activity Signature Using Selective GR Antagonism in ER-Negative Breast Cancer. PMID:29636357
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics. PMID:29625055
Prognostic DNA methylation markers for sporadic colorectal cancer: a systematic review. PMID:29564023
Overexpression of GRK6 associates with the progression and prognosis of colorectal carcinoma. PMID:29552218
CLEC1B Expression and PD-L1 Expression Predict Clinical Outcome in Hepatocellular Carcinoma with Tumor Hemorrhage. PMID:29525632
Downregulation of castor zinc finger 1 predicts poor prognosis and facilitates hepatocellular carcinoma progression via MAPK/ERK signaling. PMID:29506567
Meta-analysis of the prognostic value of long non-coding RNA AFAP1-AS1 for cancer patients in China. PMID:29487718
A Magnetic Resonance Imaging-Based Prediction Model for Prostate Biopsy Risk Stratification. PMID:29470570
CD133 expression and α-fetoprotein levels define novel prognostic subtypes of HBV-associated hepatocellular carcinoma: A long-term follow-up analysis. PMID:29435028
PIK3CA and TP53 mutations predict overall survival of stage II/III colorectal cancer patients. PMID:29434452
Glucose transporter-1 as an independent prognostic marker for cancer: a meta-analysis. PMID:29416806
The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction. PMID:29402970
Identification of new biomarkers to promote personalised treatment of patients with inflammatory rheumatic disease: protocol for an open cohort study. PMID:29391382
A robust gene signature for the prediction of early relapse in stage I-III colon cancer. PMID:29377588
Circulating Plasma Levels of miR-20b, miR-29b and miR-155 as Predictors of Bevacizumab Efficacy in Patients with Metastatic Colorectal Cancer. PMID:29361687
PITX2 DNA-methylation predicts response to anthracycline-based adjuvant chemotherapy in triple-negative breast cancer patients. PMID:29328369
Prognostic and clinicopathological significance of long noncoding RNA HOXA11-AS expression in human solid tumors: a meta-analysis. PMID:29308050
Variable selection - A review and recommendations for the practicing statistician. PMID:29292533
Pharmacogenetics of response to neoadjuvant paclitaxel treatment for locally advanced breast cancer. PMID:29290962
Evaluation of the EGFR polymorphism R497K in two cohorts of neoadjuvantly treated breast cancer patients. PMID:29267323
Enrichment of high-grade tumors in breast cancer gene expression studies. PMID:29256013
QuPath: Open source software for digital pathology image analysis. PMID:29203879
Peripheral and local predictive immune signatures identified in a phase II trial of ipilimumab with carboplatin/paclitaxel in unresectable stage III or stage IV melanoma. PMID:29157311
Subcellular localization of β-arrestin1 and its prognostic value in lung adenocarcinoma. PMID:29137031
The role of EZH2 in overall survival of colorectal cancer: a meta-analysis. PMID:29061982
CANcer-specific Evaluation System (CANES): a high-accuracy platform, for preclinical single/multi-biomarker discovery. PMID:29050243
Long non-coding RNA TUG1 as a potential prognostic biomarker in human cancers: a meta-analysis. PMID:28977959
Tissue-Based MicroRNAs as Predictors of Biochemical Recurrence after Radical Prostatectomy: What Can We Learn from Past Studies? PMID:28934131
Employment status and health related quality of life among Hodgkin-lymphoma survivors'- results based on data from a major treatment center in Hungary. PMID:28927453
Adverse prognostic value of PD-L1 expression in primary resected pulmonary squamous cell carcinomas and paired mediastinal lymph node metastases. PMID:28884747
miR-199a-3p and miR-214-3p improve the overall survival prediction of muscle-invasive bladder cancer patients after radical cystectomy. PMID:28879675
Protein expression patterns of cell cycle regulators in operable breast cancer. PMID:28797035
Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research. PMID:28777142
Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis. PMID:28751758
Role of Cytotoxic Tumor-Infiltrating Lymphocytes in Predicting Outcomes in Metastatic HER2-Positive Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial. PMID:28750133
Insulin-like Growth Factor 1 Receptor Expression in Advanced Non-small-cell Lung Cancer and its Impact on Overall Survival. PMID:28740455
PTCH1 is a reliable marker for predicting imatinib response in chronic myeloid leukemia patients in chronic phase. PMID:28704552
Collagen triple helix repeat containing-1 negatively regulated by microRNA-30c promotes cell proliferation and metastasis and indicates poor prognosis in breast cancer. PMID:28697793
Lewis x Antigen is Associated to Head and Neck Squamous Cell Carcinoma Survival. PMID:28681122
Serum levels of IGF-1 and IGF-BP3 are associated with event-free survival in adult Ewing sarcoma patients treated with chemotherapy. PMID:28652778
Did the reporting of prognostic studies of tumour markers improve since the introduction of REMARK guideline? A comparison of reporting in published articles. PMID:28614415
Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer. PMID:28522855
Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era. PMID:28497027
Ki-67 and Cell Cycle Regulators p53, p63 and cyclinD1 as Prognostic Markers for Recurrence/ Progression of Bladder Urothelial Carcinoma. PMID:28488128
Prognostic and clinicopathological role of long non-coding RNA UCA1 in various carcinomas. PMID:28423704
MMP11 and CD2 as novel prognostic factors in hormone receptor-negative, HER2-positive breast cancer. PMID:28409241
Podocalyxin-like and RNA-binding motif protein 3 are prognostic biomarkers in urothelial bladder cancer: a validatory study. PMID:28293425
Association of Hormone Receptor Expression with Survival in Ovarian Endometrioid Carcinoma: Biological Validation and Clinical Implications. PMID:28264438
Long non-coding RNA HULC as a potential prognostic biomarker in human cancers: a meta-analysis. PMID:28199963
Construction and analysis of tissue microarrays in the era of digital pathology: a pilot study targeting CDX1 and CDX2 in a colon cancer cohort of 612 patients. PMID:28138402
MicroRNA-29c-5p suppresses gallbladder carcinoma progression by directly targeting CPEB4 and inhibiting the MAPK pathway. PMID:28060377
Tat-Interacting Protein 30 (TIP30) Expression Serves as a New Biomarker for Tumor Prognosis: A Systematic Review and Meta-Analysis. PMID:28036326
BRAF-activated lncRNA predicts gastrointestinal cancer patient prognosis: a meta-analysis. PMID:28009984
Sprouty2 correlates with favorable prognosis of gastric adenocarcinoma via suppressing FGFR2-induced ERK phosphorylation and cancer progression. PMID:28002800
Prognostic Value of Plasma and Urine Glycosaminoglycan Scores in Clear Cell Renal Cell Carcinoma. PMID:27933273
Ki-67 in endometrial cancer: scoring optimization and prognostic relevance for window studies. PMID:27910946
Enrichment of C5a-C5aR axis predicts poor postoperative prognosis of patients with clear cell renal cell carcinoma. PMID:27821813
The translational potential of microRNAs as biofluid markers of urological tumours. PMID:27804986
Can we eliminate neoadjuvant chemoradiotherapy in favor of neoadjuvant multiagent chemotherapy for select stage II/III rectal adenocarcinomas: Analysis of the National Cancer Data base. PMID:27780316
Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy. PMID:27758888
Identification of BRCA1-like triple-negative breast cancers by quantitative multiplex-ligation-dependent probe amplification (MLPA) analysis of BRCA1-associated chromosomal regions: a validation study. PMID:27756336
Effect of BRCA germline mutations on breast cancer prognosis: A systematic review and meta-analysis. PMID:27749552
Interleukin-6 and C-reactive protein as prognostic biomarkers in metastatic colorectal cancer. PMID:27738330
A prospective study to assess the clinical utility of serum HER2 extracellular domain in breast cancer with HER2 overexpression. PMID:27709352
Associations of P16INK4a promoter hypermethylation with squamous intra-epithelial lesion, cervical cancer and their clinicopathological features: a meta-analysis. PMID:27669738
Systemic Inflammatory Response and Elevated Tumour Markers Predict Worse Survival in Resectable Pancreatic Ductal Adenocarcinoma. PMID:27632196
Meta-analysis of the prognostic value of abnormally expressed lncRNAs in hepatocellular carcinoma. PMID:27574455
SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer. PMID:27569656
Prognostic significance of nuclear expression of UMP-CMP kinase in triple negative breast cancer patients. PMID:27558661
TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer. PMID:27509063
Association between diabetes mellitus and the occurrence and outcome of intracerebral hemorrhage. PMID:27473136
Biomarker development in the precision medicine era: lung cancer as a case study. PMID:27388699
Long noncoding RNAs as novel predictors of survival in human cancer: a systematic review and meta-analysis. PMID:27352941
Molecular characteristics of circulating tumor cells resemble the liver metastasis more closely than the primary tumor in metastatic colorectal cancer. PMID:27340863
The prognostic value of whole blood SOX2, NANOG and OCT4 mRNA expression in advanced small-cell lung cancer. PMID:27247551
Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma. PMID:27141376
Prognostic value of Ki67 in localized prostate carcinoma: a multi-institutional study of >1000 prostatectomies. PMID:27136741
Downregulation and pro-apoptotic effect of hypoxia-inducible factor 2 alpha in hepatocellular carcinoma. PMID:27119229
Perfusion MRI as the predictive/prognostic and pharmacodynamic biomarkers in recurrent malignant glioma treated with bevacizumab: a systematic review and a time-to-event meta-analysis. PMID:27108275
Prognostic value of the DNMTs mRNA expression and genetic polymorphisms on the clinical outcome in oral cancer patients. PMID:26966018
Improving the Prognostic Ability through Better Use of Standard Clinical Data - The Nottingham Prognostic Index as an Example. PMID:26938061
Statistical aspect of translational and correlative studies in clinical trials. PMID:26932435
MicroRNA-410-5p as a potential serum biomarker for the diagnosis of prostate cancer. PMID:26900347
Immunohistochemical characterisation of molecular subtypes in endometrial cancer. PMID:26885170
MicroRNA-130b promotes proliferation and EMT-induced metastasis via PTEN/p-AKT/HIF-1α signaling. PMID:26861561
Circulating Inflammatory Mediators as Potential Prognostic Markers of Human Colorectal Cancer. PMID:26859579
Radiation-induced CD8 T-lymphocyte Apoptosis as a Predictor of Breast Fibrosis After Radiotherapy: Results of the Prospective Multicenter French Trial. PMID:26844275
CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon Cancer. PMID:26789870
Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab. PMID:26787752
Prognostic value of long noncoding RNA MALAT1 in digestive system malignancies. PMID:26770406
Can Breast Tumors Affect the Oxidative Status of the Surrounding Environment? A Comparative Analysis among Cancerous Breast, Mammary Adjacent Tissue, and Plasma. PMID:26697139
Annexin-A1 and caldesmon are associated with resistance to tamoxifen in estrogen receptor positive recurrent breast cancer. PMID:26657294
Intrinsic subtypes and genomic signatures of primary breast cancer and prognosis after systemic relapse. PMID:26651914
Distinguished prognosis after hepatectomy of HBV-related hepatocellular carcinoma with or without cirrhosis: a long-term follow-up analysis. PMID:26607653
A Systematic Review of Esophageal MicroRNA Markers for Diagnosis and Monitoring of Barrett's Esophagus. PMID:26572780
Prognostic value of preoperative lymphocyte to monocyte ratio in patients with nonmetastatic clear cell renal cell carcinoma. PMID:26508025
Association of Variants in Candidate Genes with Lipid Profiles in Women with Early Breast Cancer on Adjuvant Aromatase Inhibitor Therapy. PMID:26463708
CD24 Overexpression Is Associated with Poor Prognosis in Luminal A and Triple-Negative Breast Cancer. PMID:26444008
FGF18 as a potential biomarker in serous and mucinous ovarian tumors. PMID:26427667
Improving pancreatic cancer diagnosis using circulating tumor cells: prospects for staging and single-cell analysis. PMID:26390158
Revisiting determinants of prognosis in cutaneous melanoma. PMID:26308244
Prognostic value of cytokeratin-7 mRNA expression in peripheral whole blood of advanced lung adenocarcinoma patients. PMID:26306784
uPAR Expression Pattern in Patients with Urothelial Carcinoma of the Bladder--Possible Clinical Implications. PMID:26292086
4-protein signature predicting tamoxifen treatment outcome in recurrent breast cancer. PMID:26285647
MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer. PMID:26199650
Galectin-1, -3 and -9 Expression and Clinical Significance in Squamous Cervical Cancer. PMID:26066796
Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR. PMID:26030178
Prognostic value of HPV-mRNA in sentinel lymph nodes of cervical cancer patients with pN0-status. PMID:26008982
Enhancer of zeste homolog 2 as an independent prognostic marker for cancer: a meta-analysis. PMID:25974088
MicroRNA-21 predicts response to preoperative chemoradiotherapy in locally advanced rectal cancer. PMID:25953218
CD8+/FOXP3+-ratio in osteosarcoma microenvironment separates survivors from non-survivors: a multicenter validated retrospective study. PMID:25949908
Expression of sirtuin 1 and 2 is associated with poor prognosis in non-small cell lung cancer patients. PMID:25915617
Analyses of 7,635 Patients with Colorectal Cancer Using Independent Training and Validation Cohorts Show That rs9929218 in CDH1 Is a Prognostic Marker of Survival. PMID:25873087
Growth pattern of colorectal liver metastasis as a marker of recurrence risk. PMID:25822899
Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer. PMID:25788273
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) upregulation in breast carcinoma contributes to tumor progression and predicts early tumor recurrence. PMID:25683484
Correlation of CCNA1 promoter methylation with malignant tumors: a meta-analysis introduction. PMID:25654082
TIMP-1 and CEA as biomarkers in third-line treatment with irinotecan and cetuximab for metastatic colorectal cancer. PMID:25608838
Prognostic significance of POLE proofreading mutations in endometrial cancer. PMID:25505230
Biomarker validation and testing. PMID:25458054
Stromal expression of miR-21 identifies high-risk group in triple-negative breast cancer. PMID:25440114
MicroRNA-21 and the clinical outcomes of various carcinomas: a systematic review and meta-analysis. PMID:25376700
Survival in overweight patients with advanced pancreatic carcinoma: a multicentre cohort study. PMID:25266049
HER2-positive endometrial cancer subtype carries poor prognosis. PMID:25201050
Long noncoding RNA HOTAIR as an independent prognostic marker in cancer: a meta-analysis. PMID:25157956
Risk prediction models for biochemical recurrence after radical prostatectomy using prostate-specific antigen and Gleason score. PMID:25130472
A systematic review and meta-analysis of diagnostic and prognostic serum biomarkers of colorectal cancer. PMID:25105762
STRengthening analytical thinking for observational studies: the STRATOS initiative. PMID:25074480
Tumor heterogeneity at protein level as an independent prognostic factor in endometrial cancer. PMID:25048628
hENT1 expression is predictive of gemcitabine outcome in pancreatic cancer: a systematic review. PMID:25024604
Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer. PMID:25011585
The combination of circulating Ang1 and Tie2 levels predicts progression-free survival advantage in bevacizumab-treated patients with ovarian cancer. PMID:24947924
Prognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series. PMID:24904831
Investigation of continuous effect modifiers in a meta-analysis on higher versus lower PEEP in patients requiring mechanical ventilation--protocol of the ICEM study. PMID:24887172
The prognostic value of autophagy-related markers beclin-1 and microtubule-associated protein light chain 3B in cancers: a systematic review and meta-analysis. PMID:24838948
Expression patterns of bone morphogenetic protein antagonists in colorectal cancer desmoplastic invasion fronts. PMID:24812030
Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes. PMID:24786708
Gastric cancer research in Mexico: a public health priority. PMID:24782602
Amplification of TRIM44: pairing a prognostic target with potential therapeutic strategy. PMID:24777112
Prognostic and predictive value of cathepsin X in serum from colorectal cancer patients. PMID:24725597
Prognostic value of CpG island methylator phenotype among colorectal cancer patients: a systematic review and meta-analysis. PMID:24718889
Impact of COX2 genotype, ER status and body constitution on risk of early events in different treatment groups of breast cancer patients. PMID:24599585
Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study. PMID:24498368
Tissue prognostic biomarkers in primary cutaneous melanoma. PMID:24487785
The predictive but not prognostic value of MGMT promoter methylation status in elderly glioblastoma patients: a meta-analysis. PMID:24454798
Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial. PMID:24451146
Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development. PMID:24400218
Predicting response to epigenetic therapy. PMID:24382389
Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study. PMID:24330623
Construction and analysis of multiparameter prognostic models for melanoma outcome. PMID:24258982
Multicenter trials using ¹⁸F-fluorodeoxyglucose (FDG) PET to predict chemotherapy response: effects of differential measurement error and bias on power calculations for unselected and enrichment designs. PMID:24169628
Immune cells: plastic players along colorectal cancer progression. PMID:24151976
Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals. PMID:24107468
Somatic copy number changes in DPYD are associated with lower risk of recurrence in triple-negative breast cancers. PMID:24104963
Prognostic value of CD109+ circulating endothelial cells in recurrent glioblastomas treated with bevacizumab and irinotecan. PMID:24069296
Better reporting of scientific studies: why it matters. PMID:24013839
Biomarker-based ovarian carcinoma typing: a histologic investigation in the ovarian tumor tissue analysis consortium. PMID:23880734
Biomarkers of Helicobacter pylori-associated gastric cancer. PMID:23851317
Clinical significance of VEGFR-2 and ¹⁸F-FDG PET/CT SUVmax pretreatment score in predicting the long-term outcome of patients with locally advanced rectal cancer treated with neoadjuvant therapy. PMID:23801169
HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer. PMID:23391338
Biomarkers in reproductive medicine: the promise, and can it be fulfilled? PMID:23246448
Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profiling. PMID:23242141
Clinical prediction models for aneurysmal subarachnoid hemorrhage: a systematic review. PMID:23138544
Knowledge integration in cancer: current landscape and future prospects. PMID:23093546
Putting oncology patients at risk. PMID:23091430
Publication of tumor marker research results: the necessity for complete and transparent reporting. PMID:23071235
A simplified approach for the molecular classification of glioblastomas. PMID:23029035 -
Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration
PubMed citations: 135.
135 articles citing: Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration
Cancer Immunotherapy with Immune Checkpoint Inhibitors-Biomarkers of Response and Toxicity; Current Limitations and Future Promise. PMID:35054292
Prediction of pathological response following neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer: the PRE-PREVENCYS trial. PMID:34715822
Are There Limits in Explainability of Prognostic Biomarkers? Scrutinizing Biological Utility of Established Signatures. PMID:34680236
Stroma AReactive Invasion Front Areas (SARIFA)-A New Easily to Determine Biomarker in Colon Cancer-Results of a Retrospective Study. PMID:34638364
Human papillomavirus DNA and p16 expression in head and neck squamous cell carcinoma in young French patients. PMID:34232797
Prognostic factors for chronic post-surgical pain after lung or pleural surgery: a protocol for a systematic review and meta-analysis. PMID:34130966
RNA Binding Protein-Based Model for Prognostic Prediction of Colorectal Cancer. PMID:34080453
Validation of Selected Head and Neck Cancer Prognostic Markers from the Pathology Atlas in an Oral Tongue Cancer Cohort. PMID:34069237
NAD(P)HX epimerase downregulation promotes tumor progression through ROS/HIF-1α signaling in hepatocellular carcinoma. PMID:33932069
Clinical significance of tumor-stroma ratio in head and neck cancer: a systematic review and meta-analysis. PMID:33931044
Deep Learning Prediction of Metastasis in Locally Advanced Colon Cancer Using Binary Histologic Tumor Images. PMID:33922988
Patient-derived organoids as a predictive biomarker for treatment response in cancer patients. PMID:33846504
Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy. PMID:33805776
The Epithelial-Mesenchymal Transcription Factor Slug Predicts Survival Benefit of Up-Front Surgery in Head and Neck Cancer. PMID:33673269
VISTA Expression on Immune Cells Correlates With Favorable Prognosis in Patients With Triple-Negative Breast Cancer. PMID:33505908
Tumor associated tissue eosinophilia in oral squamous cell carcinoma: A systematic review and meta-analysis. PMID:33344159
Transfer-RNA-Derived Fragments Are Potential Prognostic Factors in Patients with Squamous Cell Carcinoma of the Head and Neck. PMID:33202812
In-depth characterization of the biomarkers based on tumor-infiltrated immune cells reveals implications for diagnosis and prognosis in hepatocellular carcinoma. PMID:33073226
Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma. PMID:33029538
Challenges and Opportunities in Clinical Applications of Blood-Based Proteomics in Cancer. PMID:32867043
ABCG2 Protein Levels and Association to Response to First-Line Irinotecan-Based Therapy for Patients with Metastatic Colorectal Cancer. PMID:32708825
Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia. PMID:32684627
A conceptual framework for prognostic research. PMID:32600262
MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients. PMID:32342233
Evolution of Estrogen Receptor Status from Primary Tumors to Metastasis and Serially Collected Circulating Tumor Cells. PMID:32326116
A systematic review of the overlap of fluid biomarkers in delirium and advanced cancer-related syndromes. PMID:32321448
Prognostic Research in Traumatic Brain Injury: Markers, Modeling, and Methodological Principles. PMID:32316847
A polymorphism within the R-spondin 2 gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab: data from FIRE-3 and TRIBE trials. PMID:32305727
Serial evaluation of serum thymidine kinase activity is prognostic in women with newly diagnosed metastatic breast cancer. PMID:32161278
Prognostic DNA methylation markers for hormone receptor breast cancer: a systematic review. PMID:32005275
Assessment of a Staging System for Sigmoid Colon Cancer Based on Tumor Deposits and Extramural Venous Invasion on Computed Tomography. PMID:31808924
How pathological criteria can impact prognosis of tongue and floor of the mouth squamous cell carcinoma. PMID:31800876
Alcohol intake, tobacco smoking, and esophageal adenocarcinoma survival: a molecular pathology epidemiology cohort study. PMID:31786674
Secretory Leukocyte Protease Inhibitor (SLPI)-A Novel Predictive Biomarker of Acute Kidney Injury after Cardiac Surgery: A Prospective Observational Study. PMID:31717603
Intra-Patient Heterogeneity of Circulating Tumor Cells and Circulating Tumor DNA in Blood of Melanoma Patients. PMID:31671846
Prognostic significance of 8-hydroxy-2'-deoxyguanosine in solid tumors: a meta-analysis. PMID:31651287
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in chronic kidney disease and acute kidney injury: a systematic review of the literature. PMID:31641330
Second-Line Systemic Treatment for Metastatic Urothelial Carcinoma: A Network Meta-Analysis of Randomized Phase III Clinical Trials. PMID:31403033
Olfactomedin 4 (OLFM4) expression is associated with nodal metastases in esophageal adenocarcinoma. PMID:31283789
Prognostic significance of cyclin D3 expression in malignancy patients: a meta-analysis. PMID:31198407
The expression of the immune checkpoint regulator VISTA correlates with improved overall survival in pT1/2 tumor stages in esophageal adenocarcinoma. PMID:31069143
Reply to 'Comment on "Tissue-infiltrating immune cells as prognostic markers in oral squamous cell carcinoma: a systematic review and meta-analysis"'. PMID:31011230
Serum ATX as a novel biomarker for breast cancer. PMID:30921203
Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach. PMID:30890775
Tissue-infiltrating immune cells as prognostic markers in oral squamous cell carcinoma: a systematic review and meta-analysis. PMID:30808992
Non-linear transformations of age at diagnosis, tumor size, and number of positive lymph nodes in prediction of clinical outcome in breast cancer. PMID:30526533
miR-330-5p targets SPRY2 to promote hepatocellular carcinoma progression via MAPK/ERK signaling. PMID:30464168
Vitamin D receptor as a marker of prognosis in oesophageal adenocarcinoma: a prospective cohort study. PMID:30344947
Prognostic values of long noncoding RNA PVT1 in various carcinomas: An updated systematic review and meta-analysis. PMID:30252166
Promise and Implementation of Proteomic Prostate Cancer Biomarkers. PMID:30158500
Systematic literature review of IL-6 as a biomarker or treatment target in patients with gastric, bile duct, pancreatic and colorectal cancer. PMID:30038723
Comprehensive transcriptomic analysis of heat shock proteins in the molecular subtypes of human breast cancer. PMID:29954368
Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): An Abridged Explanation and Elaboration. PMID:29873743
The Clinical Significance of O6-Methylguanine-DNA Methyltransferase Promoter Methylation Status in Adult Patients With Glioblastoma: A Meta-analysis. PMID:29619003
Comment on 'BAG-1 as a biomarker in early breast cancer prognosis: a systematic review with meta-analyses'. PMID:29540774
Reply to 'Comment on 'BAG-1 as a biomarker in early breast cancer prognosis: a systematic review with meta-analyses''. PMID:29540772
Association of PD-L1 and HIF-1α Coexpression with Poor Prognosis in Hepatocellular Carcinoma. PMID:29525633
Secreted and Tissue miRNAs as Diagnosis Biomarkers of Malignant Pleural Mesothelioma. PMID:29462963
A novel preoperative inflammatory marker prognostic score in patients with localized and metastatic renal cell carcinoma. PMID:29387555
Racial disparities in the rate of cardiotoxicity of HER2-targeted therapies among women with early breast cancer. PMID:29381193
A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab. PMID:29208668
Tumour budding in oral squamous cell carcinoma: a meta-analysis. PMID:29190636
Adjuvant chemotherapy for muscle-invasive bladder cancer: a systematic review and network meta-analysis of randomized clinical trials. PMID:29113380
A three gene immunohistochemical panel serves as an adjunct to clinical staging of patients with head and neck cancer. PMID:29108335
BRMS1 Expression in Surgically Resected Lung Adenocarcinoma Predicts Future Metastases and Is Associated with a Poor Prognosis. PMID:29097253
Gastric cancer: immunohistochemical classification of molecular subtypes and their association with clinicopathological characteristics. PMID:29046940
Impact of genetic variations in the MAPK signaling pathway on outcome in metastatic colorectal cancer patients treated with first-line FOLFIRI and bevacizumab: data from FIRE-3 and TRIBE trials. PMID:29045529
Radiomics: the bridge between medical imaging and personalized medicine. PMID:28975929
Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis. PMID:28751758
Radiogenomics and radiotherapy response modeling. PMID:28657906
Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer. PMID:28641578
Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification. PMID:28617804
Did the reporting of prognostic studies of tumour markers improve since the introduction of REMARK guideline? A comparison of reporting in published articles. PMID:28614415
Prognostic value of long non-coding RNA CCAT1 expression in patients with cancer: A meta-analysis. PMID:28594897
Chitotriosidase, a marker of innate immunity, is elevated in patients with primary breast cancer. PMID:28582842
Peritumoral EpCAM Is an Independent Prognostic Marker after Curative Resection of HBV-Related Hepatocellular Carcinoma. PMID:28572700
Positive Expression of Programmed Death Ligand 1 in Peritumoral Liver Tissue is Associated with Poor Survival after Curative Resection of Hepatocellular Carcinoma. PMID:28558264
Analysis of the prognostic role of an immune checkpoint score in resected non-small cell lung cancer patients. PMID:28197383
MicroRNAs miR-7 and miR-340 predict response to neoadjuvant chemotherapy in breast cancer. PMID:28181130
Topoisomerase I copy number alterations as biomarker for irinotecan efficacy in metastatic colorectal cancer. PMID:28077117
A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study. PMID:27845339
Neutrophil-to-lymphocyte ratio as a bladder cancer biomarker: Assessing prognostic and predictive value in SWOG 8710. PMID:27787873
The relationship between total and phosphorylated STAT1 and STAT3 tumour cell expression, components of tumour microenvironment and survival in patients with invasive ductal breast cancer. PMID:27769057
Clinical Application of Circulating Tumour Cells in Prostate Cancer: From Bench to Bedside and Back. PMID:27657044
A Two-Gene Prognostic Classifier for Early-Stage Lung Squamous Cell Carcinoma in Multiple Large-Scale and Geographically Diverse Cohorts. PMID:27613525
Assessment of the extent of unpublished studies in prognostic factor research: a systematic review of p53 immunohistochemistry in bladder cancer as an example. PMID:27531721
Analysis of the immune microenvironment in resected non-small cell lung cancer: the prognostic value of different T lymphocyte markers. PMID:27463005
Biomarker development in the precision medicine era: lung cancer as a case study. PMID:27388699
DMET™ (Drug Metabolism Enzymes and Transporters): a pharmacogenomic platform for precision medicine. PMID:27304055
Planning clinically relevant biomarker validation studies using the "number needed to treat" concept. PMID:27146704
Comments on a meta-analysis and systematic review of the clinicopathological significance of CDH1 in gastric cancer. PMID:27042007
Computational pathology of pre-treatment biopsies identifies lymphocyte density as a predictor of response to neoadjuvant chemotherapy in breast cancer. PMID:26882907
A history of the evolution of guidelines for reporting medical research: the long road to the EQUATOR Network. PMID:26880653
Actin-like 6A predicts poor prognosis of hepatocellular carcinoma and promotes metastasis and epithelial-mesenchymal transition. PMID:26698646
Prognostic factors for tumor recurrence in patients with clinical stage I seminoma undergoing surveillance--protocol for a systematic review. PMID:26684760
Generating and evaluating evidence of the clinical utility of molecular diagnostic tests in oncology. PMID:26633547
Cytoplasmic PML promotes TGF-β-associated epithelial-mesenchymal transition and invasion in prostate cancer. PMID:26549027
Prospective evaluation of protein C and factor VIII in prediction of cancer-associated thrombosis. PMID:26475410
Clinical value of lncRNA MALAT1 as a prognostic marker in human cancer: systematic review and meta-analysis. PMID:26423854
Presence of tumour high-endothelial venules is an independent positive prognostic factor and stratifies patients with advanced-stage oral squamous cell carcinoma. PMID:26383526
Cancer biomarker discovery and validation. PMID:26213686
RIPOSTE: a framework for improving the design and analysis of laboratory-based research. PMID:25951517
Clinicopathological significance and potential drug targeting of CDH1 in lung cancer: a meta-analysis and literature review. PMID:25931811
Next generation sequencing demonstrates association between tumor suppressor gene aberrations and poor outcome in patients with cancer. PMID:25928476
The clinicopathological significance of CDH1 in gastric cancer: a meta-analysis and systematic review. PMID:25926721
Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study. PMID:25884643
The clinicopathological significance and potential drug target of E-cadherin in NSCLC. PMID:25758052
Prognostic impact of transcription factor Fra-1 in ER-positive breast cancer: contribution to a metastatic phenotype through modulation of tumor cell adhesive properties. PMID:25666264
Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD Statement. PMID:25563062
Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement. PMID:25562432
Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement. The TRIPOD Group. PMID:25561516
A leave-one-out cross-validation SAS macro for the identification of markers associated with survival. PMID:25553357
Added predictive value of omics data: specific issues related to validation illustrated by two case studies. PMID:25352096
Tissue microRNAs as predictors of outcome in patients with metastatic colorectal cancer treated with first line Capecitabine and Oxaliplatin with or without Bevacizumab. PMID:25329796
Protein Biomarker Research in UK Hospital Clinical Biochemistry Laboratories: A Survey of Current Practice and Views. PMID:25210209
Adjusting breast cancer patient prognosis with non-HER2-gene patterns on chromosome 17. PMID:25098819
Identification of prognostic inflammatory factors in colorectal liver metastases. PMID:25069793
Association of TNFRSF10D DNA-methylation with the survival of melanoma patients. PMID:25003639
Tumour markers and kidney function: a systematic review. PMID:24689048
CD8/CD45RO T-cell infiltration in endoscopic biopsies of colorectal cancer predicts nodal metastasis and survival. PMID:24679169
Clinical proteomic biomarkers: relevant issues on study design & technical considerations in biomarker development. PMID:24679154
Prognostic and predictive value of p-Akt, EGFR, and p-mTOR in early breast cancer. PMID:24658605
RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland. PMID:24626992
TGFBI expression is an independent predictor of survival in adjuvant-treated lung squamous cell carcinoma patients. PMID:24481402
Induction of Wnt-inducible signaling protein-1 correlates with invasive breast cancer oncogenesis and reduced type 1 cell-mediated cytotoxic immunity: a retrospective study. PMID:24426833
BMC Medicine: a decade of open access medical research. PMID:24405514
Prognostic value of survivin and EGFR protein expression in triple-negative breast cancer (TNBC) patients. PMID:24233638
Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration. PMID:24228635
Serum integrin-linked kinase (sILK) concentration and survival in non-small cell lung cancer: a pilot study. PMID:23979911
Helicobacter pylori and gastritis: the role of extracellular matrix metalloproteases, their inhibitors, and the disintegrins and metalloproteases--a systematic literature review. PMID:23817928
Biomarkers in Ewing Sarcoma: The Promise and Challenge of Personalized Medicine. A Report from the Children's Oncology Group. PMID:23761859
Expression of epithelial to mesenchymal transition-related markers in lymph node metastases as a surrogate for primary tumor metastatic potential in breast cancer. PMID:23157797
Publication of tumor marker research results: the necessity for complete and transparent reporting. PMID:23071235
High TWIST1 mRNA expression is associated with poor prognosis in lymph node-negative and estrogen receptor-positive human breast cancer and is co-expressed with stromal as well as ECM related genes. PMID:22967435
Statistical challenges in the development and evaluation of marker-based clinical tests. PMID:22642713
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genetic marker
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
prognosis
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
tumor
metasource: Fairsharing.org
version: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Tags
More detailed information about this field from each metasource.
genetic marker
metasource: Fairsharing.orgversion: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
prognosis
metasource: Fairsharing.orgversion: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
tumor
metasource: Fairsharing.orgversion: FAIRsharing.org: REMARK; REporting recommendations for tumour MARKer prognostic studies; DOI: https://doi.org/10.25504/FAIRsharing.frr5dh; Last edited: Jan. 8, 2019, 1:28 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
genetic marker prognosis tumor
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