Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment
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Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment
metasource: Fairsharing.org
version: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
MIDE
metasource: Fairsharing.org
version: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
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Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment
metasource: Fairsharing.orgversion: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
MIDE
metasource: Fairsharing.orgversion: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Names
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Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment
metasource: Fairsharing.orgversion: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
MIDE
metasource: Fairsharing.orgversion: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Pharmacogenomics studies are expanding exponentially, both in terms of number and amount of data generated. To facilitate future research and diagnostic applications, Affymetrix has developed a microarray targeting known genetic variations in absorption, distribution, metabolism, excretion, toxicity (ADMET) genes. The array, known as Drug Metabolising Enzymes and Transporters (DMET Plus), comprises 1,936 variants across 231genes, including 5 copy number loci involved in drug metabolism and transport. Being designed to identify genetic variants in patients presenting different drug responses and risks for adverse drug reactions, DMET constitutes a valuable tool for pharmacogenomics and clinical studies. For effective DMET data interpretation, sharing, reporting and use across the scientific community, we propose the Minimum Information required for a DMET Experiment reporting (MIDE). MIDE aims to provide reporting guidelines and describe the information required for reporting to public databases. In this article we describe MIDE and discuss its broader applications to other platforms.
Description
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Pharmacogenomics studies are expanding exponentially, both in terms of number and amount of data generated. To facilitate future research and diagnostic applications, Affymetrix has developed a microarray targeting known genetic variations in absorption, distribution, metabolism, excretion, toxicity (ADMET) genes. The array, known as Drug Metabolising Enzymes and Transporters (DMET Plus), comprises 1,936 variants across 231genes, including 5 copy number loci involved in drug metabolism and transport. Being designed to identify genetic variants in patients presenting different drug responses and risks for adverse drug reactions, DMET constitutes a valuable tool for pharmacogenomics and clinical studies. For effective DMET data interpretation, sharing, reporting and use across the scientific community, we propose the Minimum Information required for a DMET Experiment reporting (MIDE). MIDE aims to provide reporting guidelines and describe the information required for reporting to public databases. In this article we describe MIDE and discuss its broader applications to other platforms.
metasource: Fairsharing.orgversion: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Webpage:
http://bioweb.cpgr.org.za/mide/mide.docWebpage
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http://bioweb.cpgr.org.za/mide/mide.doc
metasource: Fairsharing.orgversion: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Publications:
Publications
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Minimum information required for a DMET experiment reporting
PMID: 27548815
metasource: Fairsharing.org
version: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Publications
More detailed information about this field from each metasource.
Minimum information required for a DMET experiment reporting
PMID: 27548815
metasource: Fairsharing.org
version: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
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Minimum information required for a DMET experiment reporting
PubMed citations: 2.
2 articles citing: Minimum information required for a DMET experiment reporting
Ten simple rules for providing effective bioinformatics research support. PMID:32214318
Implementing the FAIR Data Principles in precision oncology: review of supporting initiatives. PMID:31263868
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drug metabolic process
metasource: Fairsharing.org
version: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
drug report
metasource: Fairsharing.org
version: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
gene report
metasource: Fairsharing.org
version: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
Tags
More detailed information about this field from each metasource.
drug metabolic process
metasource: Fairsharing.orgversion: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
drug report
metasource: Fairsharing.orgversion: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
gene report
metasource: Fairsharing.orgversion: FAIRsharing.org: MIDE; Minimum Information Required for a Drug Metabolism Enzymes and Transporters Experiment; DOI: https://doi.org/10.25504/FAIRsharing.jbg4kp; Last edited: March 12, 2019, 5:17 p.m.; Last accessed: Jan 03 2022 7:11 p.m.
drug metabolic process drug report gene report
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