Constraint-Based Reconstruction and Analyses of Metabolic Models: Open-Source Python Tools and Applications to Cancer.
PMID:35875150
Machine learning-guided evaluation of extraction and simulation methods for cancer patient-specific metabolic models.
PMID:35782748
Metabolic modeling-based drug repurposing in Glioblastoma.
PMID:35778411
Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0.
PMID:35773252
A pipeline for the reconstruction and evaluation of context-specific human metabolic models at a large-scale.
PMID:35749559
Metabolomic and Transcriptomic Profiling Identified Significant Genes in Thymic Epithelial Tumor.
PMID:35736499
Exploring the metabolic landscape of pancreatic ductal adenocarcinoma cells using genome-scale metabolic modeling.
PMID:35712079
Identification of Context-Specific Fitness Genes Associated With Metabolic Rearrangements for Prognosis and Potential Treatment Targets for Liver Cancer.
PMID:35646101
Genome-scale metabolic models for natural and long-term drug-induced viral control in HIV infection.
PMID:35537851
The microbiome in reproductive health: protocol for a systems biology approach using a prospective, observational study design.
PMID:35441092
Silencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is atheroprotective.
PMID:35440683
Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target.
PMID:35437144
Networks and Graphs Discovery in Metabolomics Data Analysis and Interpretation.
PMID:35350714
System-level metabolic modeling facilitates unveiling metabolic signature in exceptional longevity.
PMID:35343058
Integration of omics data to generate and analyse COVID-19 specific genome-scale metabolic models.
PMID:35339845
Compartmentalization of metabolism between cell types in multicellular organisms: a computational perspective.
PMID:35224313
Bruceine D Identified as a Drug Candidate against Breast Cancer by a Novel Drug Selection Pipeline and Cell Viability Assay.
PMID:35215292
Systems-based approaches to study immunometabolism.
PMID:35121805
Systems Biology Approaches to Decipher the Underlying Molecular Mechanisms of Glioblastoma Multiforme.
PMID:34948010
Toward modeling metabolic state from single-cell transcriptomics.
PMID:34785394
Model-based assessment of mammalian cell metabolic functionalities using omics data.
PMID:34761247
DCcov: Repositioning of drugs and drug combinations for SARS-CoV-2 infected lung through constraint-based modeling.
PMID:34723158
Discovery of Two Novel Oxidases Using a High-Throughput Activity Screen.
PMID:34709726
Omics and Computational Modeling Approaches for the Effective Treatment of Drug-Resistant Cancer Cells.
PMID:34691155
Importance of the biomass formulation for cancer metabolic modeling and drug prediction.
PMID:34622163
Genome Scale Modeling to Study the Metabolic Competition between Cells in the Tumor Microenvironment.
PMID:34572839
Robust metabolic transcriptional components in 34,494 patient-derived cancer-related samples and cell lines.
PMID:34565468
Path to improving the life cycle and quality of genome-scale models of metabolism.
PMID:34555324
Thermodynamic Genome-Scale Metabolic Modeling of Metallodrug Resistance in Colorectal Cancer.
PMID:34439283
First trimester pregnancy outcomes in a large IVF center from the Lombardy County (Italy) during the peak COVID-19 pandemic.
PMID:34400730
NICEdrug.ch, a workflow for rational drug design and systems-level analysis of drug metabolism.
PMID:34340747
Integration of transcriptional and metabolic control in macrophage activation.
PMID:34328708
Identification and Characterization of Robust Hepatocellular Carcinoma Prognostic Subtypes Based on an Integrative Metabolite-Protein Interaction Network.
PMID:34247449
SpaceM reveals metabolic states of single cells.
PMID:34226721
The Mystery of Extramitochondrial Proteins Lysine Succinylation.
PMID:34199982
Abnormal brain cholesterol homeostasis in Alzheimer's disease-a targeted metabolomic and transcriptomic study.
PMID:34075056
Metabolomics and computational analysis of the role of monoamine oxidase activity in delirium and SARS-COV-2 infection.
PMID:34017039
Molecular pathways behind acquired obesity: Adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI.
PMID:33948567
iNetModels 2.0: an interactive visualization and database of multi-omics data.
PMID:33849075
Genome Scale-Differential Flux Analysis reveals deregulation of lung cell metabolism on SARS-CoV-2 infection.
PMID:33835998
Integrating Systems and Synthetic Biology to Understand and Engineer Microbiomes.
PMID:33781078
Multi-omics approaches for revealing the complexity of cardiovascular disease.
PMID:33725119
DEXOM: Diversity-based enumeration of optimal context-specific metabolic networks.
PMID:33571201
Mapping the Metabolic Networks of Tumor Cells and Cancer-Associated Fibroblasts.
PMID:33540679
Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations.
PMID:33437055
Metabolic Reprogramming of Fibroblasts as Therapeutic Target in Rheumatoid Arthritis and Cancer: Deciphering Key Mechanisms Using Computational Systems Biology Approaches.
PMID:33374292
From Glucose to Lactate and Transiting Intermediates Through Mitochondria, Bypassing Pyruvate Kinase: Considerations for Cells Exhibiting Dimeric PKM2 or Otherwise Inhibited Kinase Activity.
PMID:33335484
Inhibiting the reproduction of SARS-CoV-2 through perturbations in human lung cell metabolic network.
PMID:33234678
The Human Protein Atlas-Spatial localization of the human proteome in health and disease.
PMID:33146890
A high-stringency blueprint of the human proteome.
PMID:33067450
Role of Glutathione in Cancer: From Mechanisms to Therapies.
PMID:33050144
Systems Biology: A Multi-Omics Integration Approach to Metabolism and the Microbiome.
PMID:32981293
Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning.
PMID:32967266
Research on the Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, According to the HUPO Human Proteome Project.
PMID:32931287
Cysteine Aminotransferase (CAT): A Pivotal Sponsor in Metabolic Remodeling and an Ally of 3-Mercaptopyruvate Sulfurtransferase (MST) in Cancer.
PMID:32882966
Deep Proteomic Deconvolution of Interferons and HBV Transfection Effects on a Hepatoblastoma Cell Line.
PMID:32685848
A Genome-Scale Metabolic Model of 2,3-Butanediol Production by Thermophilic Bacteria Geobacillus icigianus.
PMID:32635563
Prior and novel coronaviruses, Coronavirus Disease 2019 (COVID-19), and human reproduction: what is known?
PMID:32482250