DreamBASE

dreamBase (DNA Modification, RNA Regulation and Protein Binding on Expressed Pseudogenes in Human Health and Disease) is an integrated platform for analysing regualtory features of pseudogenes from multi-dimensional high-throughput sequencing data.Based on ~5500 ChIP-seq and DNase-seq data, dreamBase provides genome-wide distribution patterns of Transcription Factors, Pol II, Histone Modifications and Dnase Hypersensitivity sites around the transcription start sites of pseudognenes.By integrating ~18,000 RNA-Seq expression data, we provide the Expression Profiles of pseudogenes across 32 Cancers and 31 Normal Tissues. We also analyse the Co-Expression patterns between pseudogenes and their parent genes.Through combining predicted binding sites of microRNAs with AGO CLIP-seq data, we study the relevance of microRNAs against RNA molecules of pseudogenes at post-transcriptional level. Besides, we combine these interaction and expression data of pseudogenes, and therefore construct ceRNA networks consisted of pseudogenes and other RNAs.

Webpage:

Publications:

Publications

More detailed information about this field from each metasource. ×

http://dx.doi.org/10.1093/nar/gkx972

metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657

Close

• http://dx.doi.org/10.1093/nar/gkx972