Database of fuzzy protein complexes
Names
More detailed information about this field from each metasource.
Database of fuzzy protein complexes
metasource: Fairsharing.org
version: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
FuzDB
metasource: Fairsharing.org
version: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
fuzdb
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
Names
More detailed information about this field from each metasource.
Database of fuzzy protein complexes
metasource: Fairsharing.orgversion: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
FuzDB
metasource: Fairsharing.orgversion: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
fuzdb
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:31.198146
Names
More detailed information about this field from each metasource.
Database of fuzzy protein complexes
metasource: Fairsharing.orgversion: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
FuzDB
metasource: Fairsharing.orgversion: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
fuzdb
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:31.198146
FuzDB compiles experimentally observed fuzzy protein complexes, where intrinsic disorder (ID) is maintained upon interacting with a partner (protein, nucleic acid or small molecule) and directly impacts biological function. Entries in the database have both (i) structural evidence demonstrating the structural multiplicity or dynamic disorder of the ID region(s) in the partner bound form of the protein and (ii) in vitro or in vivo biological evidence that indicates the significance of the fuzzy region(s) in the formation, function or regulation of the assembly. Unlike the other intrinsically disordered or unfolded protein databases, FuzDB focuses on ID regions within a biological context, including higher-order assemblies and presents a detailed analysis of the structural and functional data.
Description
More detailed information about this field from each metasource.
FuzDB compiles experimentally observed fuzzy protein complexes, where intrinsic disorder (ID) is maintained upon interacting with a partner (protein, nucleic acid or small molecule) and directly impacts biological function. Entries in the database have both (i) structural evidence demonstrating the structural multiplicity or dynamic disorder of the ID region(s) in the partner bound form of the protein and (ii) in vitro or in vivo biological evidence that indicates the significance of the fuzzy region(s) in the formation, function or regulation of the assembly. Unlike the other intrinsically disordered or unfolded protein databases, FuzDB focuses on ID regions within a biological context, including higher-order assemblies and presents a detailed analysis of the structural and functional data.
metasource: Fairsharing.orgversion: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Fuzzy Complexes Database
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
The FuzDB database assembles experimentally observed fuzzy protein complexes involved in a variety of cellular processes and biomolecular condensates
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:31.198146
Webpage:
http://protdyn-database.org/Webpage
More detailed information about this field from each metasource.
http://protdyn-database.org/
metasource: Fairsharing.orgversion: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://protdyn-database.org
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
https://fuzdb.org
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:31.198146
Licence:
Name: CC-BY-NC-SA-4.0Licence name
More detailed information about this field from each metasource.
Publications:
Publications
More detailed information about this field from each metasource.
FuzDB: database of fuzzy complexes, a tool to develop stochastic structure-function relationships for protein complexes and higher-order assemblies
PMID: 27794553
metasource: Fairsharing.org
version: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
FuzDB: a new phase in understanding fuzzy interactions
PMID: 34791357
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
http://dx.doi.org/10.1093/nar/1930
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
FuzDB: database of fuzzy complexes, a tool to develop stochastic structure-function relationships for protein complexes and higher-order assemblies
PMID: 27794553
metasource: Fairsharing.org
version: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
FuzDB: a new phase in understanding fuzzy interactions
PMID: 34791357
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
http://dx.doi.org/10.1093/nar/1930
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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FuzDB: database of fuzzy complexes, a tool to develop stochastic structure-function relationships for protein complexes and higher-order assemblies
PubMed citations: 40.
40 articles citing: FuzDB: database of fuzzy complexes, a tool to develop stochastic structure-function relationships for protein complexes and higher-order assemblies
Compositional Bias of Intrinsically Disordered Proteins and Regions and Their Predictions. PMID:35883444
Predicting Protein Conformational Disorder and Disordered Binding Sites. PMID:35507260
Databases for intrinsically disordered proteins. PMID:35102880
DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation. PMID:34850135
FuzDB: a new phase in understanding fuzzy interactions. PMID:34791357
When Order Meets Disorder: Modeling and Function of the Protein Interface in Fuzzy Complexes. PMID:34680162
Advanced Sampling Methods for Multiscale Simulation of Disordered Proteins and Dynamic Interactions. PMID:34680048
Cancer-Associated Mutations Perturb the Disordered Ensemble and Interactions of the Intrinsically Disordered p53 Transactivation Domain. PMID:33984364
Fuzziness and Frustration in the Energy Landscape of Protein Folding, Function, and Assembly. PMID:33550810
MobiDB: intrinsically disordered proteins in 2021. PMID:33237329
Fuzzy protein theory for disordered proteins. PMID:33170209
The MemMoRF database for recognizing disordered protein regions interacting with cellular membranes. PMID:33119751
IDPology of the living cell: intrinsic disorder in the subcellular compartments of the human cell. PMID:32997198
Protein Databases Related to Liquid-Liquid Phase Separation. PMID:32947964
Moonlighting Proteins in the Fuzzy Logic of Cellular Metabolism. PMID:32751110
Protein-Protein Interactions Mediated by Intrinsically Disordered Protein Regions Are Enriched in Missense Mutations. PMID:32722039
Exploring Protein Intrinsic Disorder with MobiDB. PMID:32696355
Tumor-Suppressor p53TAD1-60 Forms a Fuzzy Complex with Metastasis-Associated S100A4: Structural Insights and Dynamics by an NMR/MD Approach. PMID:32511842
Sequence-based prediction of protein binding mode landscapes. PMID:32453748
Dynamic conformational flexibility and molecular interactions of intrinsically disordered proteins. PMID:32020911
Biotin proximity tagging favours unfolded proteins and enables the study of intrinsically disordered regions. PMID:31969649
LLPSDB: a database of proteins undergoing liquid-liquid phase separation in vitro. PMID:31906602
Sequence and Structure Properties Uncover the Natural Classification of Protein Complexes Formed by Intrinsically Disordered Proteins via Mutual Synergistic Folding. PMID:31683980
Disorder Mediated Oligomerization of DISC1 Proteins Revealed by Coarse-Grained Molecular Dynamics Simulations. PMID:31614085
Intrinsically Disordered Transactivation Domains Bind to TAZ1 Domain of CBP via Diverse Mechanisms. PMID:31521329
Measuring Intrinsic Disorder and Tracking Conformational Transitions Using Rosetta ResidueDisorder. PMID:31411026
Extreme Fuzziness: Direct Interactions between Two IDPs. PMID:30813629
Concomitant disorder and high-affinity zinc binding in the human zinc- and iron-regulated transport protein 4 intracellular loop. PMID:30793391
Where differences resemble: sequence-feature analysis in curated databases of intrinsically disordered proteins. PMID:30576490
IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding. PMID:29860432
Intramolecular Fuzzy Interactions Involving Intrinsically Disordered Domains. PMID:29761107
NoLogo: a new statistical model highlights the diversity and suggests new classes of Crm1-dependent nuclear export signals. PMID:29482494
DIBS: a repository of disordered binding sites mediating interactions with ordered proteins. PMID:29385418
A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer. PMID:29269425
MobiDB 3.0: more annotations for intrinsic disorder, conformational diversity and interactions in proteins. PMID:29136219
Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B. PMID:28720707
How order and disorder within paramyxoviral nucleoproteins and phosphoproteins orchestrate the molecular interplay of transcription and replication. PMID:28600653
Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness. PMID:28597296
Amino acid polymorphisms in the fibronectin-binding repeats of fibronectin-binding protein A affect bond strength and fibronectin conformation. PMID:28400484
Modeling disordered protein interactions from biophysical principles. PMID:28394890 -
FuzDB: a new phase in understanding fuzzy interactions
PubMed citations: 3.
3 articles citing: FuzDB: a new phase in understanding fuzzy interactions
Molecular Determinants of Selectivity in Disordered Complexes May Shed Light on Specificity in Protein Condensates. PMID:35053240
LLPSDB v2.0: an updated database of proteins undergoing liquid-liquid phase separation in vitro. PMID:35025997
The 2022 Nucleic Acids Research database issue and the online molecular biology database collection. PMID:34986604 - http://dx.doi.org/10.1093/nar/1930
Tags:
Tags
More detailed information about this field from each metasource.
intrinsically disordered proteins
metasource: Fairsharing.org
version: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
protein structure
metasource: Fairsharing.org
version: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
structure databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
cell biology
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
small molecules
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
protein modifications
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
transcription factors and regulatory sites
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
rna
metasource: bio.tools
version: extracted_at: 2022-11-04T11:24:31.198146
Tags
More detailed information about this field from each metasource.
intrinsically disordered proteins
metasource: Fairsharing.orgversion: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
protein structure
metasource: Fairsharing.orgversion: FAIRsharing.org: FuzDB; Database of fuzzy protein complexes; DOI: https://doi.org/10.25504/FAIRsharing.d3bm3v; Last edited: Jan. 8, 2019, 1:25 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
structure databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
cell biology
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:31.198146
small molecules
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:31.198146
protein modifications
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:31.198146
transcription factors and regulatory sites
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:31.198146
rna
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:24:31.198146
intrinsically disordered proteins protein structure structure cell biology small molecule protein modifications transcription factors and regulatory sites rna
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