Network controllability solutions for computational drug repurposing using genetic algorithms.
PMID:35082323
NetControl4BioMed: A web-based platform for controllability analysis of protein-protein interaction networks.
PMID:34352070
Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor.
PMID:33750001
A network of human functional gene interactions from knockout fitness screens in cancer cells.
PMID:30979825
NetControl4BioMed: a pipeline for biomedical data acquisition and analysis of network controllability.
PMID:30066633
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.
PMID:29915430
A novel algorithm for finding optimal driver nodes to target control complex networks and its applications for drug targets identification.
PMID:29363426
A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines.
PMID:28988802
Controlling Directed Protein Interaction Networks in Cancer.
PMID:28871116
Network Analysis Reveals A Signaling Regulatory Loop in the PIK3CA-mutated Breast Cancer Predicting Survival Outcome.
PMID:28392480
Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover.
PMID:28087713
Integrative genomic and transcriptomic analysis for pinpointing recurrent alterations of plant homeodomain genes and their clinical significance in breast cancer.
PMID:28055972
Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia.
PMID:27358048
Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.
PMID:27149990
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
PMID:26947069
ApoCanD: Database of human apoptotic proteins in the context of cancer.
PMID:26861916
dbEM: A database of epigenetic modifiers curated from cancerous and normal genomes.
PMID:26777304
Towards a compendium of essential genes - From model organisms to synthetic lethality in cancer cells.
PMID:26627871
An integrated genomic analysis of Tudor domain-containing proteins identifies PHD finger protein 20-like 1 (PHF20L1) as a candidate oncogene in breast cancer.
PMID:26588862
Public data and open source tools for multi-assay genomic investigation of disease.
PMID:26463000
Genome-Wide Detection and Analysis of Multifunctional Genes.
PMID:26436655
An integrated network platform for contextual prioritization of drugs and pathways.
PMID:26315485
Oncogenic signaling in amphiregulin and EGFR-expressing PTEN-null human breast cancer.
PMID:25454348
Identification by array comparative genomic hybridization of a new amplicon on chromosome 17q highly recurrent in BRCA1 mutated triple negative breast cancer.
PMID:25416589
Dissecting the human protein-protein interaction network via phylogenetic decomposition.
PMID:25412639
RNAi screening comes of age: improved techniques and complementary approaches.
PMID:25145850
Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer.
PMID:24970479
Influence networks based on coexpression improve drug target discovery for the development of novel cancer therapeutics.
PMID:24495353
Prediction of therapeutic microRNA based on the human metabolic network.
PMID:24403541
The PIKfyve-ArPIKfyve-Sac3 triad in human breast cancer: Functional link between elevated Sac3 phosphatase and enhanced proliferation of triple negative cell lines.
PMID:24070605
Survival of HER2-Positive Breast Cancer Cells: Receptor Signaling to Apoptotic Control Centers.
PMID:24069506
ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens.
PMID:23269662
From cancer genomes to oncogenic drivers, tumour dependencies and therapeutic targets.
PMID:22739505