R31NJMNC last accessed: 2022-11-04

BioGRID Open Repository of CRISPR Screens (ORCS)
metasource: bio.tools
version: extracted_at: 2022-11-04T11:31:37.594105

BioGRID_Open_Repository_of_CRISPR_Screens_ORCS
metasource: bio.tools
version: extracted_at: 2022-11-04T11:31:37.594105

Other names: ORCS, BioGRID ORCS, BioGRID Open Repository of CRISPR Screens (ORCS), BioGRID_Open_Repository_of_CRISPR_Screens_ORCS

BioGRID ORCS is an open repository of CRISPR screens compiled through comprehensive curation efforts. Our current index is version 1.0.3 and searches more than 49 publications and 58,161 genes to return more than 895 CRISPR screens from 3 major model organism species and 629 cell lines. All screen data are freely provided through our search index and available via download in a wide variety of standardized formats.

Webpage:

https://orcs.thebiogrid.org/

Licence:

Name: other
URL: https://opensource.org/licenses/MIT

Publications:

Publications
More detailed information about this field from each metasource.

The BioGRID interaction database: 2019 update
PMID: 30476227
metasource: Fairsharing.org
version: FAIRsharing.org: ORCS; BioGRID Open Repository of CRISPR Screens; DOI: https://doi.org/10.25504/FAIRsharing.lKaOme; Last edited: April 27, 2021, 7:46 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

metasource: bio.tools
version: extracted_at: 2022-11-04T11:31:37.594105

The BioGRID interaction database: 2019 update PubMed citations: 454.

454 articles citing: The BioGRID interaction database: 2019 update

Gene networks under circadian control exhibit diurnal organization in primate organs. PMID:35906476
Network Embedding Across Multiple Tissues and Data Modalities Elucidates the Context of Host Factors Important for COVID-19 Infection. PMID:35903362
Mitochondrial Oxidative Stress Induces Cardiac Fibrosis in Obese Rats through Modulation of Transthyretin. PMID:35897655
An accurate prediction model of digenic interaction for estimating pathogenic gene pairs of human diseases. PMID:35891796
Integration of probabilistic functional networks without an external Gold Standard. PMID:35879662
Systematic prediction of degrons and E3 ubiquitin ligase binding via deep learning. PMID:35836176
Construction and contextualization approaches for protein-protein interaction networks. PMID:35832626
Deep learning frameworks for protein-protein interaction prediction. PMID:35832624
HumanMine: advanced data searching, analysis and cross-species comparison. PMID:35820040
Bioinformatics-Driven Identification of p62 as A Crucial Oncogene in Liver Cancer. PMID:35814476
RPpocket: An RNA-Protein Intuitive Database with RNA Pocket Topology Resources. PMID:35805909
Aberrant SPOP-CHAF1A ubiquitination axis triggers tumor autophagy that endows a therapeutical vulnerability in diffuse large B cell lymphoma. PMID:35773729
Inferring functional communities from partially observed biological networks exploiting geometric topology and side information. PMID:35760826
Deep learning uncovers distinct behavior of rice network to pathogens response. PMID:35754717
Systematic inference of indirect transcriptional regulation by protein kinases and phosphatases. PMID:35731801
Network approaches for modeling the effect of drugs and diseases. PMID:35704883
Assessing sequence-based protein-protein interaction predictors for use in therapeutic peptide engineering. PMID:35688894
A comprehensive SARS-CoV-2-human protein-protein interactome network identifies pathobiology and host-targeting therapies for COVID-19. PMID:35677070
Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19. PMID:35676404
An approach to cellular tropism of SARS-CoV-2 through protein-protein interaction and enrichment analysis. PMID:35672403
Network assisted analysis of de novo variants using protein-protein interaction information identified 46 candidate genes for congenital heart disease. PMID:35671298
Predicting which genes will respond to transcription factor perturbations. PMID:35666184
SSRTool: A web tool for evaluating RNA secondary structure predictions based on species-specific functional interpretability. PMID:35664227
A tensor-based bi-random walks model for protein function prediction. PMID:35637427
Immunopathogenic overlap between COVID-19 and tuberculosis identified from transcriptomic meta-analysis and human macrophage infection. PMID:35634577
Comprehensive Interactome Mapping of Nuclear Receptors Using Proximity Biotinylation. PMID:35612745
Targeting TROY-mediated P85a/AKT/TBX3 signaling attenuates tumor stemness and elevates treatment response in hepatocellular carcinoma. PMID:35610614
GenePlexus: a web-server for gene discovery using network-based machine learning. PMID:35580053
Identification of Potential Muscle Biomarkers in McArdle Disease: Insights from Muscle Proteome Analysis. PMID:35563042
SynLethDB 2.0: a web-based knowledge graph database on synthetic lethality for novel anticancer drug discovery. PMID:35562840
Bioinformatics-Based Approaches to Study Virus-Host Interactions During SARS-CoV-2 Infection. PMID:35554909
SARS-CoV-2 Employ BSG/CD147 and ACE2 Receptors to Directly Infect Human Induced Pluripotent Stem Cell-Derived Kidney Podocytes. PMID:35517495
A hybrid approach unveils drug repurposing candidates targeting an Alzheimer pathophysiology mechanism. PMID:35510183
GURFAP: A Platform for Gene Function Analysis in Glycyrrhiza Uralensis. PMID:35495163
Membranome 3.0: Database of single-pass membrane proteins with AlphaFold models. PMID:35481632
PregTox: A Resource of Knowledge about Drug Fetal Toxicity. PMID:35469349
On the influence of several factors on pathway enrichment analysis. PMID:35453140
Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer. PMID:35437317
Integrative Analysis for Identification of Therapeutic Targets and Prognostic Signatures in Non-Small Cell Lung Cancer. PMID:35422618
Phylogenetic profiling in eukaryotes: The effect of species, orthologous group, and interactome selection on protein interaction prediction. PMID:35421089
Predicted mouse interactome and network-based interpretation of differentially expressed genes. PMID:35390003
DWPPI: A Deep Learning Approach for Predicting Protein-Protein Interactions in Plants Based on Multi-Source Information With a Large-Scale Biological Network. PMID:35387292
Multiomic profiling of the acute stress response in the mouse hippocampus. PMID:35383160
CPIELA: Computational Prediction of Plant Protein-Protein Interactions by Ensemble Learning Approach From Protein Sequences and Evolutionary Information. PMID:35360876
Computational methods, databases and tools for synthetic lethality prediction. PMID:35352098
Protein Biomarkers in Monocytes and CD4+ Lymphocytes for Predicting Lithium Treatment Response of Bipolar Disorder: a Feasibility Study with Tyramine-Based Signal-Amplified Flow Cytometry. PMID:35342205
Serine hydroxymethyltransferase 2 (SHMT2) potentiates the aggressive process of oral squamous cell carcinoma by binding to interleukin enhancer-binding factor 2 (ILF2). PMID:35333683
Dynamical Analysis of a Boolean Network Model of the Oncogene Role of lncRNA ANRIL and lncRNA UFC1 in Non-Small Cell Lung Cancer. PMID:35327612
BRCA1 mutations in high-grade serous ovarian cancer are associated with proteomic changes in DNA repair, splicing, transcription regulation and signaling. PMID:35292711
A comprehensive WGS-based pipeline for the identification of new candidate genes in inherited retinal dystrophies. PMID:35246562
Host-microbiome protein-protein interactions capture disease-relevant pathways. PMID:35246229
The microprotein Nrs1 rewires the G1/S transcriptional machinery during nitrogen limitation in budding yeast. PMID:35239649
PSINDB: the postsynaptic protein-protein interaction database. PMID:35234850
Comprehensive Analysis of the Glycolysis-Related Gene Prognostic Signature and Immune Infiltration in Endometrial Cancer. PMID:35223866
Functional network motifs defined through integration of protein-protein and genetic interactions. PMID:35223214
Antifungal activity of an artificial peptide aptamer SNP-D4 against Fusarium oxysporum. PMID:35223198
Single-Cell Technologies to Decipher the Immune Microenvironment in Myeloid Neoplasms: Perspectives and Opportunities. PMID:35186713
The S100A7 nuclear interactors in autoimmune diseases: a coevolutionary study in mammals. PMID:35174412
KeyPathwayMineR: De Novo Pathway Enrichment in the R Ecosystem. PMID:35173764
Using Surface Hydrophobicity Together with Empirical Potentials to Identify Protein-Protein Binding Sites: Application to the Interactions of E-cadherins. PMID:35167069
The Landscape of Aminoacyl-tRNA Synthetases Involved in Severe Acute Respiratory Syndrome Coronavirus 2 Infection. PMID:35153822
An Integrative Network Approach to Identify Common Genes for the Therapeutics in Tuberculosis and Its Overlapping Non-Communicable Diseases. PMID:35153741
Chemoproteomic-enabled characterization of small GTPase Rab1a as a target of an N-arylbenzimidazole ligand's rescue of Parkinson's-associated cell toxicity. PMID:35128413
Transcriptomic Landscape of Herbivore Oviposition in Arabidopsis: A Systematic Review. PMID:35126411
Structure-based prediction of HDAC6 substrates validated by enzymatic assay reveals determinants of promiscuity and detects new potential substrates. PMID:35110592
Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource. PMID:35078504
Towards an Ideal In Cell Hybridization-Based Strategy to Discover Protein Interactomes of Selected RNA Molecules. PMID:35055128
Correcting Differential Gene Expression Analysis for Cyto-Architectural Alterations in Substantia Nigra of Parkinson's Disease Patients Reveals Known and Potential Novel Disease-Associated Genes and Pathways. PMID:35053314
Multi-time scale transcriptomic analysis on the dynamic process of tamoxifen resistance development in breast cancer cell lines. PMID:35041152
Plant Reactome and PubChem: The Plant Pathway and (Bio)Chemical Entity Knowledgebases. PMID:35037224
RNA-binding protein p54nrb/NONO potentiates nuclear EGFR-mediated tumorigenesis of triple-negative breast cancer. PMID:35013116
RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers. PMID:35006434
Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutations in isogenic disease models. PMID:34997121
Potential Molecular Mechanisms and Remdesivir Treatment for Acute Respiratory Syndrome Corona Virus 2 Infection/COVID 19 Through RNA Sequencing and Bioinformatics Analysis. PMID:34992355
Single-cell transcriptome atlas of human mesenchymal stem cells exploring cellular heterogeneity. PMID:34965030
Data analysis methods for defining biomarkers from omics data. PMID:34951658
Spatial and Temporal Expression of High-Mobility-Group Nucleosome-Binding (HMGN) Genes in Brain Areas Associated with Cognition in Individuals with Down Syndrome. PMID:34946949
GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation. PMID:34933446
Small molecules for cell reprogramming: a systems biology analysis. PMID:34919532
Where all the Roads Meet? A Crossover Perspective on Host Factors Regulating SARS-CoV-2 infection. PMID:34914966
Protein-protein interactions: Methods, databases, and applications in virus-host study. PMID:34909403
Improving Analysis and Annotation of Microarray Data with Protein Interactions. PMID:34902122
Shared Molecular Mechanisms between Atherosclerosis and Periodontitis by Analyzing the Transcriptomic Alterations of Peripheral Blood Monocytes. PMID:34899963
Interrogating cell type-specific cooperation of transcriptional regulators in 3D chromatin. PMID:34888502
Metabolic endophenotype associated with right ventricular glucose uptake in pulmonary hypertension. PMID:34888034
Computational Network Pharmacology-Based Strategy to Capture Key Functional Components and Decode the Mechanism of Chai-Hu-Shu-Gan-San in Treating Depression. PMID:34867413
GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors. PMID:34857890
Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease. PMID:34857794
Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases. PMID:34857024
Inhibitor tolerance and bioethanol fermentability of levoglucosan-utilizing Escherichia coli were enhanced by overexpression of stress-responsive gene ycfR: The proteomics-guided metabolic engineering. PMID:34853817
BP180/Collagen XVII: A Molecular View. PMID:34830116
Transcription Factor Action Orchestrates the Complex Expression Pattern of CRABS CLAW in Arabidopsis. PMID:34828269
CyFi-MAP: an interactive pathway-based resource for cystic fibrosis. PMID:34782688
Pairwise Biological Network Alignment Based on Discrete Bat Algorithm. PMID:34777564
Individualized Proteogenomics Reveals the Mutational Landscape of Melanoma Patients in Response to Immunotherapy. PMID:34771574
Systematic Analysis of FASTK Gene Family Alterations in Cancer. PMID:34768773
Computational methods for protein localization prediction. PMID:34765098
Recognition of DNA Methylation Molecular Features for Diagnosis and Prognosis in Gastric Cancer. PMID:34745226
TcoFBase: a comprehensive database for decoding the regulatory transcription co-factors in human and mouse. PMID:34718747
Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation. PMID:34709266
A Graph Feature Auto-Encoder for the prediction of unobserved node features on biological networks. PMID:34706640
ANAT 3.0: a framework for elucidating functional protein subnetworks using graph-theoretic and machine learning approaches. PMID:34706638
A Markov random field model for network-based differential expression analysis of single-cell RNA-seq data. PMID:34702190
Biallelic FRA10AC1 variants cause a neurodevelopmental disorder with growth retardation. PMID:34694367
DeepTrio: a ternary prediction system for protein-protein interaction using mask multiple parallel convolutional neural networks. PMID:34694333
Precise Characterization of Genetic Interactions in Cancer via Molecular Network Refining Processes. PMID:34681774
Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition. PMID:34673281
Sequence-Based Prediction of Plant Protein-Protein Interactions by Combining Discrete Sine Transformation With Rotation Forest. PMID:34671178
Two classes of functional connectivity in dynamical processes in networks. PMID:34665977
SYNBIP: synthetic binding proteins for research, diagnosis and therapy. PMID:34664670
Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma. PMID:34662337
A Systematic Analysis Identifies Key Regulators Involved in Cell Proliferation and Potential Drugs for the Treatment of Human Lung Adenocarcinoma. PMID:34650921
Differential Transcriptional Regulation of Polymorphic p53 Codon 72 in Metabolic Pathways. PMID:34639134
Predicting PY motif-mediated protein-protein interactions in the Nedd4 family of ubiquitin ligases. PMID:34637467
SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks. PMID:34634810
A survey on computational methods in discovering protein inhibitors of SARS-CoV-2. PMID:34623382
An overview of machine learning methods for monotherapy drug response prediction. PMID:34619752
iRegNet: an integrative Regulatory Network analysis tool for Arabidopsis thaliana. PMID:34618085
Estrogen Hormone Is an Essential Sex Factor Inhibiting Inflammation and Immune Response in COVID-19. PMID:34611658
Systems biology analysis of lung fibrosis-related genes in the bleomycin mouse model. PMID:34588506
CPLM 4.0: an updated database with rich annotations for protein lysine modifications. PMID:34581824
Defining Functions of Mannoproteins in Saccharomyces cerevisiae by High-Dimensional Morphological Phenotyping. PMID:34575807
Network neighbors of viral targets and differentially expressed genes in COVID-19 are drug target candidates. PMID:34556735
Vtc5 Is Localized to the Vacuole Membrane by the Conserved AP-3 Complex to Regulate Polyphosphate Synthesis in Budding Yeast. PMID:34544285
Proteomic Tools for the Analysis of Cytoskeleton Proteins. PMID:34542864
GRASP55 restricts early-stage autophagy and regulates spatial organization of the early secretory network. PMID:34533192
The protein-protein interaction network alignment using recurrent neural network. PMID:34529185
Time-resolved in vivo ubiquitinome profiling by DIA-MS reveals USP7 targets on a proteome-wide scale. PMID:34518535
MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity. PMID:34517762
Protein Arginine Methyltransferase 5 Functions via Interacting Proteins. PMID:34513846
ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 Susceptibility. PMID:34512723
Identifying Protein Complexes With Clear Module Structure Using Pairwise Constraints in Protein Interaction Networks. PMID:34512712
A functionally divergent intrinsically disordered region underlying the conservation of stochastic signaling. PMID:34506483
Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy. PMID:34493662
Arabidopsis-Based Dual-Layered Biological Network Analysis Elucidates Fully Modulated Pathways Related to Sugarcane Resistance on Biotrophic Pathogen Infection. PMID:34490009
Machine learning methods, databases and tools for drug combination prediction. PMID:34477201
ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1. PMID:34474245
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology. PMID:34467244
CANVS: an easy-to-use application for the analysis and visualization of mass spectrometry-based protein-protein interaction/association data. PMID:34432510
MetaCancer: A deep learning-based pan-cancer metastasis prediction model developed using multi-omics data. PMID:34429856
MeCP2 prevents age-associated cognitive decline via restoring synaptic plasticity in a senescence-accelerated mouse model. PMID:34363729
Global effects of RAB3GAP1 dysexpression on the proteome of mouse cortical neurons. PMID:34363538
Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast. PMID:34358317
Nitrate triggered phosphoproteome changes and a PIN2 phosphosite modulating root system architecture. PMID:34357701
Thiol-disulphide independent in-cell trapping for the identification of peroxiredoxin 2 interactors. PMID:34340028
Comprehensive Analysis of the Value of SMYD Family Members in the Prognosis and Immune Infiltration of Malignant Digestive System Tumors. PMID:34335697
Multimodal single-cell omics analysis identifies epithelium-immune cell interactions and immune vulnerability associated with sex differences in COVID-19. PMID:34330889
Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang. PMID:34297769
Identification and Validation of Potential Biomarkers and Pathways for Idiopathic Pulmonary Fibrosis by Comprehensive Bioinformatics Analysis. PMID:34285914
YPIBP: A repository for phosphoinositide-binding proteins in yeast. PMID:34285772
An integrative study of genetic variants with brain tissue expression identifies viral etiology and potential drug targets of multiple sclerosis. PMID:34284104
NTNG1 Modulates Cisplatin Resistance in Epithelial Ovarian Cancer Cells via the GAS6/AXL/Akt Pathway. PMID:34277602
A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases. PMID:34253785
Loss of UCHL1 rescues the defects related to Parkinson's disease by suppressing glycolysis. PMID:34244144
A quantitative yeast aging proteomics analysis reveals novel aging regulators. PMID:34241809
The Silence of PSMC6 Inhibits Cell Growth and Metastasis in Lung Adenocarcinoma. PMID:34239933
Databases for Protein-Protein Interactions. PMID:34236665
Integrated analysis of Shank1 PDZ interactions with C-terminal and internal binding motifs. PMID:34235485
Integration of transcriptomic data identifies key hallmark genes in hypertrophic cardiomyopathy. PMID:34225646
Linear functional organization of the omic embedding space. PMID:34213534
Pathogen Moonlighting Proteins: From Ancestral Key Metabolic Enzymes to Virulence Factors. PMID:34203698
Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms. PMID:34197603
A systems pharmacology approach based on oncogenic signalling pathways to determine the mechanisms of action of natural products in breast cancer from transcriptome data. PMID:34193143
Network-based analysis of virulence factors for uncovering Aeromonas veronii pathogenesis. PMID:34162325
Precision omics data integration and analysis with interoperable ontologies and their application for COVID-19 research. PMID:34159360
Insights into how environment shapes post-mortem RNA transcription in mouse brain. PMID:34155272
Interferon-Gamma-Producing CD8+ Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor-Colitis. PMID:34147519
Dynamic Host Immune and Transcriptomic Responses to Respiratory Syncytial Virus Infection in a Vaccination-Challenge Mouse Model. PMID:34138405
Making fundamental scientific discoveries by combining information from literature, databases, and computational tools - An example. PMID:34136100
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins. PMID:34133714
The expression and clinical prognostic value of protein phosphatase 1 catalytic subunit beta in pancreatic cancer. PMID:34125004
Target identification among known drugs by deep learning from heterogeneous networks. PMID:34123272
DeepR2cov: deep representation learning on heterogeneous drug networks to discover anti-inflammatory agents for COVID-19. PMID:34117734
Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias. PMID:34113825
Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment. PMID:34108016
PIGNON: a protein-protein interaction-guided functional enrichment analysis for quantitative proteomics. PMID:34088263
Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila. PMID:34086947
A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3. PMID:34073619
Model-based analysis uncovers mutations altering autophagy selectivity in human cancer. PMID:34059679
Natural variants suppress mutations in hundreds of essential genes. PMID:34042294
Genetic interaction network has a very limited impact on the evolutionary trajectories in continuous culture-grown populations of yeast. PMID:34039270
driveR: a novel method for prioritizing cancer driver genes using somatic genomics data. PMID:34030627
Circulating hsa-miR-323b-3p in Huntington's Disease: A Pilot Study. PMID:34025560
KEA3: improved kinase enrichment analysis via data integration. PMID:34019655
A computational approach for detecting physiological homogeneity in the midst of genetic heterogeneity. PMID:34015270
An overview of graph databases and their applications in the biomedical domain. PMID:34003247
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics. PMID:33979648
A unified resource and configurable model of the synapse proteome and its role in disease. PMID:33976238
Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase. PMID:33974913
CLEP: A Hybrid Data- and Knowledge- Driven Framework for Generating Patient Representations. PMID:33964127
Proteo3Dnet: a web server for the integration of structural information with interactomics data. PMID:33963857
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. PMID:33961781
A New Sequential Forward Feature Selection (SFFS) Algorithm for Mining Best Topological and Biological Features to Predict Protein Complexes from Protein-Protein Interaction Networks (PPINs). PMID:33959851
Employing core regulatory circuits to define cell identity. PMID:33934382
The EAR Motif in the Arabidopsis MADS Transcription Factor AGAMOUS-Like 15 Is Not Necessary to Promote Somatic Embryogenesis. PMID:33924312
An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19. PMID:33895786
The VRNetzer platform enables interactive network analysis in Virtual Reality. PMID:33893283
Genetic Architecture Underlying Nascent Speciation-The Evolution of Eurasian Pigs under Domestication. PMID:33892509
Correlation AnalyzeR: functional predictions from gene co-expression correlations. PMID:33879054
Modeling transcriptional regulation using gene regulatory networks based on multi-omics data sources. PMID:33874910
Algorithm-Based Meta-Analysis Reveals the Mechanistic Interaction of the Tumor Suppressor LIMD1 With Non-Small-Cell Lung Carcinoma. PMID:33869018
RRM2B Is Frequently Amplified Across Multiple Tumor Types: Implications for DNA Repair, Cellular Survival, and Cancer Therapy. PMID:33868369
Non-Genomic AhR-Signaling Modulates the Immune Response in Endotoxin-Activated Macrophages After Activation by the Environmental Stressor BaP. PMID:33868237
PCprophet: a framework for protein complex prediction and differential analysis using proteomic data. PMID:33859439
A novel predicted ADP-ribosyltransferase-like family conserved in eukaryotic evolution. PMID:33854844
A combined RAD-Seq and WGS approach reveals the genomic basis of yellow color variation in bumble bee Bombus terrestris. PMID:33846496
Exploring the Imbalance of Periodontitis Immune System From the Cellular to Molecular Level. PMID:33841510
High ELF4 expression in human cancers is associated with worse disease outcomes and increased resistance to anticancer drugs. PMID:33836003
Reprogramming enriches for somatic cell clones with small-scale mutations in cancer-associated genes. PMID:33831558
Posttranslational modifications in proteins: resources, tools and prediction methods. PMID:33826699
In silico investigation of the viroporin E as a vaccine target against SARS-CoV-2. PMID:33822639
A bioinformatic analysis of the inhibin-betaglycan-endoglin/CD105 network reveals prognostic value in multiple solid tumors. PMID:33819300
Network bioinformatics analysis provides insight into drug repurposing for COVID-19. PMID:33817623
Improved sequence-based prediction of interaction sites in α-helical transmembrane proteins by deep learning. PMID:33815689
Huntingtin: A Protein with a Peculiar Solvent Accessible Surface. PMID:33809039
Quantitative Proteomic Approach Reveals Altered Metabolic Pathways in Response to the Inhibition of Lysine Deacetylases in A549 Cells under Normoxia and Hypoxia. PMID:33806075
Detection of H3K4me3 Identifies NeuroHIV Signatures, Genomic Effects of Methamphetamine and Addiction Pathways in Postmortem HIV+ Brain Specimens that Are Not Amenable to Transcriptome Analysis. PMID:33805201
Assessing the Function of the ZFP90 Variant rs1170426 in SLE and the Association Between SLE Drug Target and Susceptibility Genes. PMID:33796098
Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment. PMID:33791705
A Critical Role of Peptidylprolyl Isomerase A Pseudogene 22/microRNA-197-3p/Peptidylprolyl Isomerase A Axis in Hepatocellular Carcinoma. PMID:33790943
Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells. PMID:33788831
Protein interaction potential landscapes for yeast replicative aging. PMID:33785798
Genome-wide RNAi screen for regulators of UPRmt in Caenorhabditis elegans mutants with defects in mitochondrial fusion. PMID:33784383
Adenosine Receptor and Its Downstream Targets, Mod(mdg4) and Hsp70, Work as a Signaling Pathway Modulating Cytotoxic Damage in Drosophila. PMID:33777958
The Genetic and Epigenetic Mechanisms Involved in Irreversible Pulp Neural Inflammation. PMID:33777260
Versatile knowledge guided network inference method for prioritizing key regulatory factors in multi-omics data. PMID:33762588
SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt. PMID:33761321
Integrated intra- and intercellular signaling knowledge for multicellular omics analysis. PMID:33749993
Integrating 3D structural information into systems biology. PMID:33744294
Identification of disease treatment mechanisms through the multiscale interactome. PMID:33741907
Genetic Interaction Network Interpretation: A Tidy Data Science Perspective. PMID:33733367
Molecular clues in the regulation of mini-puberty involve neuronal DNA binding transcription factor NHLH2. PMID:33731013
Gene variants of coagulation related proteins that interact with SARS-CoV-2. PMID:33730015
Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen. PMID:33727531
Alternatively Splicing Interactomes Identify Novel Isoform-Specific Partners for NSD2. PMID:33718354
Do Molecular Profiles of Primary Versus Metastatic Radioiodine Refractory Differentiated Thyroid Cancer Differ? PMID:33716974
Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. PMID:33713620
Integrative analysis regarding the correlation between GAS2 family genes and human glioma prognosis. PMID:33713047
B7-H6 is a new potential biomarker and therapeutic target of T-lymphoblastic lymphoma. PMID:33708955
Systemic Multi-Omics Analysis Reveals Amplified P4HA1 Gene Associated With Prognostic and Hypoxic Regulation in Breast Cancer. PMID:33692831
Mutational Pattern in Multiple Pulmonary Nodules Are Associated With Early Stage Lung Adenocarcinoma. PMID:33680914
HIR V2: a human interactome resource for the biological interpretation of differentially expressed genes via gene set linkage analysis. PMID:33677507
Structural basis for the DNA-binding activity of human ARID4B Tudor domain. PMID:33675746
Molecular disruption of DNA polymerase β for platinum sensitisation and synthetic lethality in epithelial ovarian cancers. PMID:33674744
The overexpression of DNA repair genes in invasive ductal and lobular breast carcinomas: Insights on individual variations and precision medicine. PMID:33662042
Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia. PMID:33649590
Cysteinyl-specialized proresolving mediators link resolution of infectious inflammation and tissue regeneration via TRAF3 activation. PMID:33649212
Hippocampal transcriptome-wide association study and neurobiological pathway analysis for Alzheimer's disease. PMID:33630843
Identification of host proteins differentially associated with HIV-1 RNA splice variants. PMID:33629952
Evolution, structure and emerging roles of C1ORF112 in DNA replication, DNA damage responses, and cancer. PMID:33625522
Ageing transcriptome meta-analysis reveals similarities and differences between key mammalian tissues. PMID:33611312
Genome-wide association analysis of cognitive function in Danish long-lived individuals. PMID:33607172
The Srs2 helicase dampens DNA damage checkpoint by recycling RPA from chromatin. PMID:33602817
WDR5 facilitates EMT and metastasis of CCA by increasing HIF-1α accumulation in Myc-dependent and independent pathways. PMID:33601056
Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns. PMID:33588752
The CLAIRE COVID-19 initiative: approach, experiences and recommendations. PMID:33584129
Systematic characterization of mutations altering protein degradation in human cancers. PMID:33567269
RNA Sequencing Reveals Distinct Immune Responses in the Chorioamniotic Membranes of Women with Preterm Labor and Microbial or Sterile Intra-amniotic Inflammation. PMID:33558326
Bioinformatics analyses of significant genes, related pathways, and candidate diagnostic biomarkers and molecular targets in SARS-CoV-2/COVID-19. PMID:33553808
BioMaster: An Integrated Database and Analytic Platform to Provide Comprehensive Information About BioBrick Parts. PMID:33552037
Protein-protein interaction analysis reveals a novel cancer stem cell related target TMEM17 in colorectal cancer. PMID:33549114
Degree Adjusted Large-Scale Network Analysis Reveals Novel Putative Metabolic Disease Genes. PMID:33546175
Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia. PMID:33527899
Human pathways in animal models: possibilities and limitations. PMID:33524155
The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress. PMID:33523898
Structural similarity-based prediction of host factors associated with SARS-CoV-2 infection and pathogenesis. PMID:33506741
Intestinal mRNA expression profile and bioinformatics analysis in a methamphetamine-induced mouse model of inflammatory bowel disease. PMID:33490181
NLPEI: A Novel Self-Interacting Protein Prediction Model Based on Natural Language Processing and Evolutionary Information. PMID:33488064
Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection. PMID:33441564
Application of graphical lasso in estimating network structure in gene set. PMID:33437755
Combined RNA/tissue profiling identifies novel Cancer/testis genes. PMID:33426787
An Integrative Computational Approach for the Prediction of Human-Plasmodium Protein-Protein Interactions. PMID:33426052
Model systems for studying polyphosphate biology: a focus on microorganisms. PMID:33420907
Identification and Characterization of Plant-Interacting Targets of Tomato Spotted Wilt Virus Silencing Suppressor. PMID:33401462
Distinct p63 and p73 Protein Interactions Predict Specific Functions in mRNA Splicing and Polyploidy Control in Epithelia. PMID:33375680
Metric Labeling and Semimetric Embedding for Protein Annotation Prediction. PMID:33370163
PICKLE 3.0: Enriching the human Meta-database with the mouse protein interactome extended via mouse-human orthology. PMID:33367505
Dosage-sensitive molecular mechanisms are associated with the tissue-specificity of traits and diseases. PMID:33363699
Multi-resolution visualization and analysis of biomolecular networks through hierarchical community detection and web-based graphical tools. PMID:33351828
Mouse Embryonic Fibroblast Adipogenic Potential: A Comprehensive Transcriptome Analysis. PMID:33345692
SECAT: Quantifying Protein Complex Dynamics across Cell States by Network-Centric Analysis of SEC-SWATH-MS Profiles. PMID:33333029
TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) Interaction. PMID:33324648
Differential Co-Expression Analyses Allow the Identification of Critical Signalling Pathways Altered during Tumour Transformation and Progression. PMID:33322692
Protein Interaction Network Biology in Neuroscience. PMID:33314619
Suboptimal Global Transcriptional Response Increases the Harmful Effects of Loss-of-Function Mutations. PMID:33306797
Applications and advancements of FT-ICR-MS for interactome studies. PMID:33289940
Active Learning for Node Classification: An Evaluation. PMID:33286933
A Novel Proximity Biotinylation Assay Based on the Self-Associating Split GFP1-10/11. PMID:33276494
CovMulNet19, Integrating Proteins, Diseases, Drugs, and Symptoms: A Network Medicine Approach to COVID-19. PMID:33274348
Filamin A Orchestrates Cytoskeletal Structure, Cell Migration and Stem Cell Characteristics in Human Seminoma TCam-2 Cells. PMID:33266100
Drug2ways: Reasoning over causal paths in biological networks for drug discovery. PMID:33264280
Towards a unified open access dataset of molecular interactions. PMID:33262342
A ligand-based computational drug repurposing pipeline using KNIME and Programmatic Data Access: case studies for rare diseases and COVID-19. PMID:33250934
TRP Channels Regulation of Rho GTPases in Brain Context and Diseases. PMID:33240883
A thorough analysis of the contribution of experimental, derived and sequence-based predicted protein-protein interactions for functional annotation of proteins. PMID:33237964
The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets. PMID:33237311
PINA 3.0: mining cancer interactome. PMID:33231689
Inferring the molecular and phenotypic impact of amino acid variants with MutPred2. PMID:33219223
Predicted rat interactome database and gene set linkage analysis. PMID:33216897
Emerging Evidences for an Implication of the Neurodegeneration-Associated Protein TAU in Cancer. PMID:33207722
The IMEx coronavirus interactome: an evolving map of Coronaviridae-host molecular interactions. PMID:33206959
In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis. PMID:33200027
DPPN-SVM: Computational Identification of Mis-Localized Proteins in Cancers by Integrating Differential Gene Expressions With Dynamic Protein-Protein Interaction Networks. PMID:33193746
Virtual screening and network pharmacology-based synergistic mechanism identification of multiple components contained in Guanxin V against coronary artery disease. PMID:33187508
YQFC: a web tool to compare quantitative biological features between two yeast gene lists. PMID:33186464
A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming. PMID:33184234
LL-37-Induced Autophagy Contributed to the Elimination of Live Porphyromonas gingivalis Internalized in Keratinocytes. PMID:33178622
Amyotrophic Lateral Sclerosis Is Accompanied by Protein Derangements in the Olfactory Bulb-Tract Axis. PMID:33167591
A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19. PMID:33156843
Human Gene Functional Network-Informed Prediction of HIV-1 Host Dependency Factors. PMID:33144314
ACE2 Netlas: In-silico functional characterization and drug-gene interactions of ACE2 gene network to understand its potential involvement in COVID-19 susceptibility. PMID:33140059
BIKE regulates dengue virus infection and is a cellular target for broad-spectrum antivirals. PMID:33137362
iCSDB: an integrated database of CRISPR screens. PMID:33137185
Synthetic Lethality through the Lens of Medicinal Chemistry. PMID:33135887
TCONS_00012883 promotes proliferation and metastasis via DDX3/YY1/MMP1/PI3K-AKT axis in colorectal cancer. PMID:33135346
IHP-PING-generating integrated human protein-protein interaction networks on-the-fly. PMID:33129201
Plasma Proteomics Identify Biomarkers and Pathogenesis of COVID-19. PMID:33128875
FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts. PMID:33124732
Designing a Network Proximity-Based Drug Repurposing Strategy for COVID-19. PMID:33123533
In silico Method in CRISPR/Cas System: An Expedite and Powerful Booster. PMID:33123486
Virus-Host Protein-Protein Interactions between Human Papillomavirus 16 E6 A1 and D2/D3 Sub-Lineages: Variances and Similarities. PMID:33121134
Comprehensive Evaluation of Endocytosis-Associated Protein SCAMP3 in Hepatocellular Carcinoma. PMID:33116758
Roles of Farnesyl-Diphosphate Farnesyltransferase 1 in Tumour and Tumour Microenvironments. PMID:33113804
FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update. PMID:33104800
Evolution of Sequence-based Bioinformatics Tools for Protein-protein Interaction Prediction. PMID:33093807
Assessing the Direct Binding of Ark-Like E3 RING Ligases to Ubiquitin and Its Implication on Their Protein Interaction Network. PMID:33086510
Predicted functional interactome of Caenorhabditis elegans and a web tool for the functional interpretation of differentially expressed genes. PMID:33076954
The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions. PMID:33070389
Comparative Toxicogenomics Database (CTD): update 2021. PMID:33068428
A review of protein-protein interaction network alignment: From pathway comparison to global alignment. PMID:33033584
Serpin peptidase inhibitor clade A member 1-overexpression in gastric cancer promotes tumor progression in vitro and is associated with poor prognosis. PMID:33014156
Pseudo2GO: A Graph-Based Deep Learning Method for Pseudogene Function Prediction by Borrowing Information From Coding Genes. PMID:33014009
CRISP-view: a database of functional genetic screens spanning multiple phenotypes. PMID:33010154
In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm. PMID:33006999
Robust edge-based biomarker discovery improves prediction of breast cancer metastasis. PMID:32998692
PML Regulates the Epidermal Differentiation Complex and Skin Morphogenesis during Mouse Embryogenesis. PMID:32992884
DIGGER: exploring the functional role of alternative splicing in protein interactions. PMID:32976589
The effect of hybridization on transposable element accumulation in an undomesticated fungal species. PMID:32955438
Benchmarking orthology methods using phylogenetic patterns defined at the base of Eukaryotes. PMID:32935832
Potential impact on coagulopathy of gene variants of coagulation related proteins that interact with SARS-CoV-2. PMID:32935103
Comparative host-pathogen protein-protein interaction analysis of recent coronavirus outbreaks and important host targets identification. PMID:32914167
Comprehensive host-pathogen protein-protein interaction network analysis. PMID:32912135
A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation. PMID:32911434
Transcription Factors That Regulate the Pathogenesis of Ulcerative Colitis. PMID:32908909
Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer. PMID:32908313
GAB2 and GAB3 are expressed in a tumor stage-, grade- and histotype-dependent manner and are associated with shorter progression-free survival in ovarian cancer. PMID:32888136
RNA-binding and prion domains: the Yin and Yang of phase separation. PMID:32857852
Analysis of APPL1 Gene Polymorphisms in Patients with a Phenotype of Maturity Onset Diabetes of the Young. PMID:32854233
Determining the interaction status and evolutionary fate of duplicated homomeric proteins. PMID:32853212
Systems Biology Approaches to Understanding the Human Immune System. PMID:32849587
RNA-protein interaction mapping via MS2- or Cas13-based APEX targeting. PMID:32839320
SARS-CoV-2-human protein-protein interaction network. PMID:32838020
A Human IgSF Cell-Surface Interactome Reveals a Complex Network of Protein-Protein Interactions. PMID:32822567
Analytical Guidelines for co-fractionation Mass Spectrometry Obtained through Global Profiling of Gold Standard Saccharomyces cerevisiae Protein Complexes. PMID:32817346
NPF:network propagation for protein function prediction. PMID:32787776
Transcriptomic analysis delineates potential signature genes and miRNAs associated with the pathogenesis of asthma. PMID:32770056
FLUTE: Fast and reliable knowledge retrieval from biomedical literature. PMID:32761077
NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency. PMID:32744500
FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination. PMID:32719125
Piggybacking on Classical Import and Other Non-Classical Mechanisms of Nuclear Import Appear Highly Prevalent within the Human Proteome. PMID:32718019
Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins. PMID:32697195
Analyzing IDPs in Interactomes. PMID:32696395
Robustness of plant quantitative disease resistance is provided by a decentralized immune network. PMID:32669441
Seedling Chloroplast Responses Induced by N-Linolenoylethanolamine Require Intact G-Protein Complexes. PMID:32665332
Structural biology of DNA abasic site protection by SRAP proteins. PMID:32663791
Leveraging the Comparative Toxicogenomics Database to Fill in Knowledge Gaps for Environmental Health: A Test Case for Air Pollution-induced Cardiovascular Disease. PMID:32663284
Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling. PMID:32614325
Seq-ing answers: Current data integration approaches to uncover mechanisms of transcriptional regulation. PMID:32612756
Association study based on topological constraints of protein-protein interaction networks. PMID:32612246
Extensive signal integration by the phytohormone protein network. PMID:32612234
Genome-wide investigation of gene-cancer associations for the prediction of novel therapeutic targets in oncology. PMID:32612205
Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis. PMID:32603655
Phosphoproteome Response to Dithiothreitol Reveals Unique Versus Shared Features of Saccharomyces cerevisiae Stress Responses. PMID:32597660
Exploring whole-genome duplicate gene retention with complex genetic interaction analysis. PMID:32586993
Role of Anillin in Tumour: From a Prognostic Biomarker to a Novel Target. PMID:32560530
Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR. PMID:32542389
A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation. PMID:32494624
Identification and characterization of male reproduction-related genes in pig (Sus scrofa) using transcriptome analysis. PMID:32487021
Protein Network Studies on PCOS Biomarkers With S100A8, Druggability Assessment, and RNA Aptamer Designing to Control Its Cyst Migration Effect. PMID:32478041
dbPSP 2.0, an updated database of protein phosphorylation sites in prokaryotes. PMID:32472030
A Bayesian data fusion based approach for learning genome-wide transcriptional regulatory networks. PMID:32471360
piNET: a versatile web platform for downstream analysis and visualization of proteomics data. PMID:32469073
Pleiotropic Roles of Calmodulin in the Regulation of KRas and Rac1 GTPases: Functional Diversity in Health and Disease. PMID:32456244
Genome-Wide Analysis of the GRAS Gene Family in Barley (Hordeum vulgare L.). PMID:32423019
Mutation severity spectrum of rare alleles in the human genome is predictive of disease type. PMID:32413045
The multifaceted nature of αB-crystallin. PMID:32383140
Targeting ERK-Hippo Interplay in Cancer Therapy. PMID:32375238
Community curation in PomBase: enabling fission yeast experts to provide detailed, standardized, sharable annotation from research publications. PMID:32353878
Hepatitis B Virus Core Particles Containing a Conserved Region of the G Protein Combined with Interleukin-35 Protected Mice against Respiratory Syncytial Virus Infection without Vaccine-Enhanced Immunopathology. PMID:32321805
Fold-Change-Specific Enrichment Analysis (FSEA): Quantification of Transcriptional Response Magnitude for Functional Gene Groups. PMID:32316383
Structured reviews for data and knowledge-driven research. PMID:32283553
Bioinformatics Analysis for Multiple Gene Expression Profiles in Sepsis. PMID:32280132
Essential gene prediction in Drosophila melanogaster using machine learning approaches based on sequence and functional features. PMID:32257045
Sex-specific and shared expression profiles of vulnerability and resilience to trauma in brain and blood. PMID:32228684
Absence of Nuclear p16 Is a Diagnostic and Independent Prognostic Biomarker in Squamous Cell Carcinoma of the Cervix. PMID:32204550
Multi-level and lineage-specific interactomes of the Hox transcription factor Ubx contribute to its functional specificity. PMID:32170121
A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation. PMID:32163402
Genetic and Chemical-Genetic Interactions Map Biogenesis and Permeability Determinants of the Outer Membrane of Escherichia coli. PMID:32156814
Transcript profiling reveals potential regulators for oxidative stress response of a necrotrophic chickpea pathogen Ascochyta rabiei. PMID:32117678
RhoBTB Proteins Regulate the Hippo Pathway by Antagonizing Ubiquitination of LKB1. PMID:32111652
Genetic Modifiers and Rare Mendelian Disease. PMID:32106447
Predicted Drosophila Interactome Resource and web tool for functional interpretation of differentially expressed genes. PMID:32103267
Data libraries - the missing element for modeling biological systems. PMID:32100391
Diverse and dynamic roles of F-box proteins in plant biology. PMID:32072251
Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract. PMID:32066429
Exploration of databases and methods supporting drug repurposing: a comprehensive survey. PMID:32055842
Alpha-Synuclein Physiology and Pathology: A Perspective on Cellular Structures and Organelles. PMID:32038126
In Silico Strategies in Tuberculosis Drug Discovery. PMID:32033144
Genome-wide identification of cold responsive transcription factors in Brassica napus L. PMID:32028890
Unraveling the role of salt-sensitivity genes in obesity with integrated network biology and co-expression analysis. PMID:32027667
PIPE4: Fast PPI Predictor for Comprehensive Inter- and Cross-Species Interactomes. PMID:31996697
Open Data for Differential Network Analysis in Glioma. PMID:31952211
Domain-mediated interactions for protein subfamily identification. PMID:31937869
Structure of the BRK domain of the SWI/SNF chromatin remodeling complex subunit BRG1 reveals a potential role in protein-protein interactions. PMID:31909846
Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy. PMID:31907603
Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells. PMID:31901729
AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair. PMID:31900314
Transcription factor regulatory modules provide the molecular mechanisms for functional redundancy observed among transcription factors in yeast. PMID:31881824
Analysis of Differentially Expressed Genes in Coronary Artery Disease by Integrated Microarray Analysis. PMID:31881747
MASS SPECTROMETRY IN VIROLOGICAL SCIENCES. PMID:31876329
The Emerging Role of Cytidine Deaminase in Human Diseases: A New Opportunity for Therapy? PMID:31870623
Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways. PMID:31868589
Common Neurodegeneration-Associated Proteins Are Physiologically Expressed by Human B Lymphocytes and Are Interconnected via the Inflammation/Autophagy-Related Proteins TRAF6 and SQSTM1. PMID:31824497
Transcriptome Meta-Analysis Deciphers a Dysregulation in Immune Response-Associated Gene Signatures during Sepsis. PMID:31817302
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis. PMID:31806906
Sequence-Derived Markers of Drug Targets and Potentially Druggable Human Proteins. PMID:31803227
The Alliance of Genome Resources: Building a Modern Data Ecosystem for Model Organism Databases. PMID:31796553
TGFB1-Mediated Gliosis in Multiple Sclerosis Spinal Cords Is Favored by the Regionalized Expression of HOXA5 and the Age-Dependent Decline in Androgen Receptor Ligands. PMID:31779094
A single ChIP-seq dataset is sufficient for comprehensive analysis of motifs co-occurrence with MCOT package. PMID:31750523
Sudden unexpected death in asymptomatic infants due to PPA2 variants. PMID:31705601
The Monarch Initiative in 2019: an integrative data and analytic platform connecting phenotypes to genotypes across species. PMID:31701156
AppleMDO: A Multi-Dimensional Omics Database for Apple Co-Expression Networks and Chromatin States. PMID:31695717
Therapeutic target database 2020: enriched resource for facilitating research and early development of targeted therapeutics. PMID:31691823
SIGNOR 2.0, the SIGnaling Network Open Resource 2.0: 2019 update. PMID:31665520
DNA Replication Inhibitor Geminin and Retinoic Acid Signaling Participate in Complex Interactions Associated With Pluripotency. PMID:31659113
Bovine Genome Database: new annotation tools for a new reference genome. PMID:31647100
Integrated bioinformatics analysis reveals role of the LINC01093/miR-96-5p/ZFAND5/NF-κB signaling axis in hepatocellular carcinoma. PMID:31641376
Biological Network Approaches and Applications in Rare Disease Studies. PMID:31614842
VarSite: Disease variants and protein structure. PMID:31606900
Alliance of Genome Resources Portal: unified model organism research platform. PMID:31552413
Computer aided analysis of disease linked protein networks. PMID:31485137
Protein-Protein Interactions in Candida albicans. PMID:31440220
Network dynamics of the yeast methyltransferome. PMID:31403050
Hallmarks of ribosomopathies. PMID:31350888
Identification of important invasion and proliferation related genes in adrenocortical carcinoma. PMID:31321566
Ultra-soft X-ray system for imaging the early cellular responses to X-ray induced DNA damage. PMID:31318974
Comprehensive in vivo identification of the c-Myc mRNA protein interactome using HyPR-MS. PMID:31296583
Proteomics Approaches for Biomarker and Drug Target Discovery in ALS and FTD. PMID:31244593
Gene Information eXtension (GIX): effortless retrieval of gene product information on any website. PMID:31217594
A Robust Approach for Identification of Cancer Biomarkers and Candidate Drugs. PMID:31212673
To Embed or Not: Network Embedding as a Paradigm in Computational Biology. PMID:31118945
ResponseNet v.3: revealing signaling and regulatory pathways connecting your proteins and genes across human tissues. PMID:31114913
Cell contact and Nf2/Merlin-dependent regulation of TEAD palmitoylation and activity. PMID:31043565
Mining Featured Biomarkers Linked with Epithelial Ovarian CancerBased on Bioinformatics. PMID:30970615

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More detailed information about this field from each metasource.

crispr
metasource: Fairsharing.org
version: FAIRsharing.org: ORCS; BioGRID Open Repository of CRISPR Screens; DOI: https://doi.org/10.25504/FAIRsharing.lKaOme; Last edited: April 27, 2021, 7:46 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

cell line
metasource: Fairsharing.org
version: FAIRsharing.org: ORCS; BioGRID Open Repository of CRISPR Screens; DOI: https://doi.org/10.25504/FAIRsharing.lKaOme; Last edited: April 27, 2021, 7:46 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

gene
metasource: Fairsharing.org
version: FAIRsharing.org: ORCS; BioGRID Open Repository of CRISPR Screens; DOI: https://doi.org/10.25504/FAIRsharing.lKaOme; Last edited: April 27, 2021, 7:46 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

metasource: re3data.org
version: re3data.org: BioGRID ORCS; editing status 2019-10-23; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R31NJMNC last accessed: 2022-11-04

gene knockout
metasource: Fairsharing.org
version: FAIRsharing.org: ORCS; BioGRID Open Repository of CRISPR Screens; DOI: https://doi.org/10.25504/FAIRsharing.lKaOme; Last edited: April 27, 2021, 7:46 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

high throughput screening
metasource: Fairsharing.org
version: FAIRsharing.org: ORCS; BioGRID Open Repository of CRISPR Screens; DOI: https://doi.org/10.25504/FAIRsharing.lKaOme; Last edited: April 27, 2021, 7:46 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

phenotype
metasource: Fairsharing.org
version: FAIRsharing.org: ORCS; BioGRID Open Repository of CRISPR Screens; DOI: https://doi.org/10.25504/FAIRsharing.lKaOme; Last edited: April 27, 2021, 7:46 a.m.; Last accessed: Jan 03 2022 7:07 p.m.

drosophila melanogaster
metasource: re3data.org
version: re3data.org: BioGRID ORCS; editing status 2019-10-23; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R31NJMNC last accessed: 2022-11-04

enzyme
metasource: re3data.org
version: re3data.org: BioGRID ORCS; editing status 2019-10-23; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R31NJMNC last accessed: 2022-11-04

homo sapiens
metasource: re3data.org
version: re3data.org: BioGRID ORCS; editing status 2019-10-23; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R31NJMNC last accessed: 2022-11-04

mus musculus
metasource: re3data.org
version: re3data.org: BioGRID ORCS; editing status 2019-10-23; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R31NJMNC last accessed: 2022-11-04

protein
metasource: re3data.org
version: re3data.org: BioGRID ORCS; editing status 2019-10-23; re3data.org - Registry of Research Data Repositories. http://doi.org/10.17616/R31NJMNC last accessed: 2022-11-04

genetics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:31:37.594105

crispr cell line gene gene knockout high throughput screening phenotype drosophila melanogaster enzyme homo sapiens mus musculus protein genetics

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